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Aneurysmal subarachnoid hemorrhage

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https://www.readbyqxmd.com/read/29449516/-a-case-of-a-ruptured-cerebral-aneurysm-associated-with-microscopic-polyangiitis
#1
Toshihide Takahashi, Wataru Katayama, Yuji Kujiraoka, Tetsuya Yamamoto, Akira Matsumura
CASE: A 71-year-old woman was receiving dialysis for microscopic polyangiitis(MPA). She was transported to the emergency room after developing a headache and losing consciousness. She was in a coma and had dense left paralysis. Head computed tomography(CT)showed a subarachnoid hemorrhage. Head three-dimensional CT angiography showed an aneurysm proximal to the right M2(inferior trunk), which was considered as the source of bleeding. We performed an emergency aneurysm clipping surgery...
February 2018: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/29445965/traumatic-subarachnoid-hemorrhage-related-to-ophthalmic-artery-avulsion-a-case-report
#2
Alessandro Prior, Luca Allegretti, Ilaria Melloni, Marta Bovio, Francesco Laganà, Marco Ceraudo, Gianluigi Zona
We present a case of ophthalmic artery (OA) traumatic avulsion, leading to a post-traumatic subarachnoid hemorrhage (SAH) with ventricular blood invasion and hydrocephalus, mimicking an internal carotid aneurysm rupture. This is the third case of such an event reported in literature and the first without orbital fractures and optic nerve avulsion. Conservative treatment was sufficient for the avulsion, but surgery was needed for the coexisting eye luxation. Traumatic OA avulsion is a rare but possible event and should be suspected in case of basal cisterns SAH, evidence of orbital trauma and CT angiogram or angiographic absence of opacification of the OA...
February 14, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29445430/seizure-prophylaxis-in-the-immediate-post-hemorrhagic-period-in-patients-with-aneurysmal-subarachnoid-hemorrhage
#3
Thomas V Kodankandath, Salman Farooq, Wled Wazni, John-Andrew Cox, Christopher Southwood, Gregory Rozansky, Vijay Johnson, John R Lynch
Introduction: Seizures are a well-known complication of aneurysmal subarachnoid hemorrhage (aSAH) and occur most commonly in the immediate posthemorrhagic period. Most commonly used antiepileptic drugs (AEDs) for seizure prophylaxis in aSAH include phenytoin and levetiracetam. There is no reliable data available on the safety and efficacy of restricting AED prophylaxis only till the aneurysm is secured. Methods: We retrospectively chart reviewed patients admitted to our neurosciences intensive care unit (NICU) with aSAH during the past two years...
December 2017: Journal of Vascular and Interventional Neurology
https://www.readbyqxmd.com/read/29445328/hippocampal-atrophy-following-subarachnoid-hemorrhage-correlates-with-disruption-of-astrocyte-morphology-and-capillary-coverage-by-aqp4
#4
Maryam Anzabi, Maryam Ardalan, Nina K Iversen, Ali H Rafati, Brian Hansen, Leif Østergaard
Despite successful management of ruptured intracranial aneurysm following subarachnoid hemorrhage (SAH), delayed cerebral ischemia (DCI) remains the main cause of high mortality and morbidity in patients who survive the initial bleeding. Astrocytes play a key role in neurovascular coupling. Therefore, changes in the neurovascular unit including astrocytes following SAH may contribute to the development of DCI and long-term complications. In this study, we characterized morphological changes in hippocampal astrocytes following experimental SAH, with special emphasis on glia-vascular cross-talk and hippocampal volume changes...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29437934/morphological-characteristics-associated-with-the-rupture-risk-of-mirror-posterior-communicating-artery-aneurysms
#5
Guang-Xian Wang, Jun Liu, You-Qiang Chen, Li Wen, Ming-Guang Yang, Ming-Fu Gong, Dong Zhang
OBJECTIVE: Patient related clinical factors and intracranial aneurysms (IAs) at different locations may lead to statistical bias when investigating the rupture risk of IAs. Thus the purpose of this study was to identify the morphological parameters that are related to the rupture of mirror posterior communicating artery aneurysms (PComAAs). METHODS: Between August 2011 and July 2017, 68 patients with mirror PComAAs and aneurysmal subarachnoid hemorrhage were diagnosed by CT angiography at three medical centers...
February 2, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29435280/analysis-of-the-clinical-characteristics-of-hemorrhagic-moyamoya-disease-in-the-jilin-province-of-northeastern-china-a-single-center-study-of-212-cases
#6
Qinglian Li, Lai Qu, Yongjie Yuan, Baofeng Xu, Yunbao Guo, Kan Xu, Jinlu Yu
The present study aimed to investigate the clinical characteristics of hemorrhagic moyamoya disease (MMD) in Jilin province in northeast China. A total of 212 cases of hemorrhagic MMD were consecutively enrolled from the First Hospital of Jilin University in Changchun, China between January 2011 and January 2015. The patients' general clinical data, including age and gender characteristics, history of previous illnesses, hemorrhage type and onset symptoms, Hunt-Hess classification at admission, imaging characteristics, association with aneurysms, treatments and prognosis, were recorded and analyzed using SPSS 19...
February 2018: Biomedical Reports
https://www.readbyqxmd.com/read/29434767/simvastatin-inhibits-the-apoptosis-of-hippocampal-cells-in-a-mouse-model-of-alzheimer-s-disease
#7
Xiaoqin Hu, Chengwei Song, Ming Fang, Chengyan Li
Alzheimer's disease is associated with cognitive impairments that affect memory and executive functions. Simvastatin is a cholesterol-lowering statin drug that is used to control levels of cholesterol in the blood, particularly in cases of hypercholesterolemia, and may be used in the treatment of aneurysmal subarachnoid hemorrhage. Previous results have indicated that the apoptosis of hippocampal cells may serve a critical role in the progression of Alzheimer's disease. In the present study, it was determined whether Simvastatin inhibited the apoptosis of hippocampal cells in vitro and in vivo ...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29428981/factors-associated-with-clinical-and-radiological-status-on-admission-in-patients-with-aneurysmal-subarachnoid-hemorrhage
#8
Daniel W Zumofen, Michel Roethlisberger, Rita Achermann, Schatlo Bawarjan, Martin N Stienen, Christian Fung, Donato D'Alonzo, Nicolai Maldaner, Andrea Ferrari, Marco V Corniola, Daniel Schoeni, Johannes Goldberg, Daniele Valsecchi, Thomas Robert, Rodolfo Maduri, Martin Seule, Jan-Karl Burkhardt, Serge Marbacher, Philippe Bijlenga, Kristine A Blackham, Heiner C Bucher, Luigi Mariani, Raphael Guzman
Grading scales yield objective measure of the severity of aneurysmal subarachnoid hemorrhage and serve as to guide treatment decisions and for prognostication. The purpose of this cohort study was to determine what factors govern a patient's disease-specific admission scores in a representative Central European cohort. The Swiss Study of Subarachnoid Hemorrhage includes anonymized data from all tertiary referral centers serving subarachnoid hemorrhage patients in Switzerland. The 2009-2014 dataset was used to evaluate the impact of patient and aneurysm characteristics on the patients' status at admission using descriptive and multivariate regression analysis...
February 10, 2018: Neurosurgical Review
https://www.readbyqxmd.com/read/29425980/dose-dependent-effects-of-statins-for-patients-with-aneurysmal-subarachnoid-hemorrhage-meta-regression-analysis
#9
REVIEW
Minh-Son To, Shivesh Prakash, Santosh I Poonnoose, Shailesh Bihari
OBJECTIVE: The study utilizes meta-regression analysis to quantify the dose-dependent effects of statin pharmacotherapy on vasospasm, delayed ischemic neurologic deficits (DINDs) and mortality in aneurysmal subarachnoid hemorrhage (aSAH). METHODS: Prospective, retrospective observational studies and randomized controlled trials (RCTs) were retrieved by a systematic database search. Summary estimates were expressed as absolute risk (AR) for a given statin dose or control (placebo)...
February 6, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29424648/association-of-plasma-d-dimer-level-with-thromboembolic-events-after-endovascular-coil-treatment-of-ruptured-cerebral-aneurysms
#10
Hitoshi Fukuda, Akira Handa, Masaomi Koyanagi, Benjamin Lo, Sen Yamagata
OBJECTIVE Although endovascular therapy is favored for acutely ruptured intracranial aneurysms, hematological factors associated with acute subarachnoid hemorrhage (SAH) may predispose to procedure-related ischemic complications. The aim of this study was to evaluate whether an elevated level of plasma D-dimer, a parameter of hypercoagulation in patients with acute SAH, is correlated with increased incidence of thromboembolic events during endovascular coiling of ruptured aneurysms. METHODS The authors analyzed data from 103 cases of acutely ruptured aneurysms (in 103 patients) treated with endovascular coil embolization at a single institution...
February 9, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29422847/intraoperative-rupture-of-unruptured-cerebral-aneurysm-during-craniotomy-a-case-report
#11
Kenji Yoshiki, Kouichi Misaki, Iku Nambu, Issei Fukui, Masanao Mohri, Naoyuki Uchiyama, Mitsutoshi Nakada
An unruptured aneurysm was incidentally found in the right middle cerebral artery in a 67-year-old woman. During an attempt to turn the temporalis muscle for surgical clipping, systolic blood pressure suddenly increased. After opening the dura mater, we found a subarachnoid hemorrhage and severe brain swelling. We promptly expanded the craniotomy area to reach the aneurysm while pulling part of the frontal lobe to apply a clip. We retrospectively analyzed the aneurysm using computational fluid dynamics. Our analysis suggests that the rupture of the aneurysm occurred at a location with very low wall shear stress...
September 2017: Case Reports in Neurology
https://www.readbyqxmd.com/read/29422364/glioblastoma-arising-within-sites-of-encephalomalacia-from-cerebrovascular-insult-two-cases-and-a-review-of-the-literature
#12
Emily A Ferenczi, Altaf Saadi, Shamik Bhattacharyya, Aaron L Berkowitz
Glioblastoma is the most common primary parenchymal brain malignancy, with median survival of less than one year. While there are likely multiple predisposing genetic and environmental factors in glioblastoma formation, chronic inflammation resulting from non-traumatic vascular brain injury is one proposed risk factor for oncogenesis. Here, we report two instances of glioblastoma arising within areas of encephalomalacia caused by remote vascular insults (one following aneurysmal subarachnoid hemorrhage and one following ischemic infarction), review the literature associating glioblastoma with prior brain injury, and discuss potential mechanisms for malignant transformation in injured brain tissue...
February 5, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29421452/marriage-and-partnership-integrity-after-aneurysmal-sah-small-alterations-in-neurological-status-matter-most
#13
Daniel Schöni, Lara Lauber, Christian Fung, Johannes Goldberg, René Müri, Andreas Raabe, Thomas Nyffeler, Jürgen Beck
Common sequelae of subarachnoid hemorrhage (SAH) include somatic and/or cognitive impairment. This can cause emotional stress, social tensions, and difficulties in relationships. To test our hypothesis that more severe somatic and cognitive impairments increased the likelihood of disruption of a relationship after SAH, we assessed the integrity of marriage or partnership status in a well-evaluated subset of SAH patients.; Abbreviations: GOSE: extended Glasgow outcome scale;mRS: modified Rankin scale;SAH: subarachnoid hemorrhage...
February 5, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29420354/the-rise-and-fall-of-transcranial-doppler-ultrasonography-for-the-diagnosis-of-vasospasm-in-aneurysmal-subarachnoid-hemorrhage
#14
Réza Behrouz
No abstract text is available yet for this article.
February 7, 2018: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/29417227/risk-of-de-novo-aneurysm-formation-in-patients-with-unruptured-intracranial-aneurysms
#15
Enrico Giordan, Waleed Brinjikji, Roanna L Vine, Giuseppe Lanzino
BACKGROUND AND PURPOSE: The rate of de novo aneurysm formation in patients with unruptured aneurysm without history of subarachnoid hemorrhage is scarcely defined in literature. We report the incidence of de novo aneurysm formation in a large contemporary series of patients with unruptured intracranial aneurysm (UIA) undergoing serial neurovascular imaging. METHODS: Neurovascular imaging studies of 321 consecutive UIA patients with no prior history of subarachnoid hemorrhage, with at least 3 years of follow-up imaging, were reviewed by a neuroradiologist and a neurosurgeon...
February 7, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29414883/possible-role-of-inflammation-and-galectin-3-in-brain-injury-after-subarachnoid-hemorrhage
#16
REVIEW
Hirofumi Nishikawa, Hidenori Suzuki
Aneurysmal subarachnoid hemorrhage (SAH) is known as one of the most devastating diseases in the central nervous system. In the past few decades, research on SAH has focused on cerebral vasospasm to prevent post-SAH delayed cerebral ischemia (DCI) and to improve outcomes. However, increasing evidence has suggested that early brain injury (EBI) is an important mechanism contributing to DCI, cerebral vasospasm as well as poor outcomes. Though the mechanism of EBI is very complex, inflammation is thought to play a pivotal role in EBI...
February 7, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29414507/a-comparison-of-contrast-free-mra-at-3-0t-in-cases-of-intracranial-aneurysms-with-or-without-subarachnoid-hemorrhage
#17
Ruifang Yan, Bo Zhang, Long Wang, Qiang Li, Fengmei Zhou, Jipeng Ren, Zhansheng Zhai, Zheng Li, Hongkai Cui
PURPOSE: To determine the diagnostic accuracy of contrast-free MRA at 3.0T for detection of intracranial aneurysms in patients with subarachnoid hemorrhage. METHODS: 411 patients (183 with SAH and 228 with non-SAH) underwent MRA. Accuracy, sensitivity, specificity, positive predictive values (PPV), and negative predictive values (NPV) were measured and compared with DSA. RESULTS: Except for a slight difference in sensitivity in patient-based and aneurysm-based evaluations (P=0...
October 25, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29412162/diagnostic-performance-of-different-perfusion-algorithms-for-the-detection-of-angiographical-spasm
#18
Saif Afat, Carolin Brockmann, Omid Nikoubashman, Marguerite Muller, Kolja M Thierfelder, Wolfgang G Kunz, Ulrike Haberland, Marc A Brockmann, Konstantin Nikolaou, Martin Wiesmann, Ahmed E Othman
PURPOSE: To assess the diagnostic utility of different perfusion algorithms for the detection of angiographical arterial spasm. METHOD: During a 2-year period, 45 datasets from 29 patients (54.2±10,75y,20F) with suspected cerebral vasospasm after aneurysmal subarachnoid hemorrhage were included. Volume Perfusion CT (VPCT), Non-enhanced CT (NCT) and angiography were performed within 6hours post-ictus. Perfusion maps were generated using a maximum slope (MS) and a deconvolution-based approach (DC)...
February 2, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29410300/median-supraorbital-keyhole-approach-for-clipping-ruptured-distal-anterior-cerebral-artery-aneurysm-a-technical-report-with-review-of-literature
#19
Sivashanmugam Dhandapani, Sushant Kumar Sahoo
BACKGROUND: Minimally invasive approach to distal anterior cerebral artery (DACA) aneurysms could not gain much acceptance due to the difficulties associated with conventional frontal paramedian approach. The more proximal basal interhemispheric approach however necessitated extensive dissection of soft tissues. We describe a minimally invasive median supraorbital keyhole craniotomy with basal interhemispheric approach for clipping a ruptured DACA aneurysm. METHODS: A 62-year-old patient presented with subarachnoid hemorrhage...
February 1, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29410174/mortality-after-spontaneous-subarachnoid-hemorrhage-causality-and-validation-of-a-prediction-model
#20
Yasser B Abulhasan, Najayeb Alabdulraheem, Gabrielle Simoneau, Mark R Angle, Jeanne Teitelbaum
OBJECTIVE: To evaluate primary causes of death after spontaneous subarachnoid hemorrhage (SAH) and externally validate the HAIR score, a prognostication tool, in a single academic institution. METHODS: We reviewed all SAH patients admitted to our Neuro-ICU between 2010 and 2016. Univariate and multivariate logistic regressions were performed to identify predictors of in-hospital mortality. The HAIR score predictors were Hunt and Hess grade at treatment decision, age, intraventricular hemorrhage, and re-bleeding within 24 hours...
January 31, 2018: World Neurosurgery
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