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https://www.readbyqxmd.com/read/28231590/endotypes-in-chronic-rhinosinusitis-biomarkers-based-on-a-mechanistic-insight-for-targeted-treatment
#1
Martin Wagenmann, Kathrin Scheckenbach, Adam M Chaker
Chronic rhinosinusitis is an umbrella term for several phenotypes and mechanistically distinct inflammatory diseases of the nose and the paranasal sinuses affecting around 11% of the population in Europe and the USA. Approximately 20% of the patients present with uncontrolled disease despite adequate treatment, and revision surgery is common. While a clinical characterization alone does not improve treatment results, novel but expensive biologics have increasingly become available, but they require a better understanding of the mechanism...
February 24, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28231348/association-between-bone-graft-volume-and-maxillary-sinus-membrane-elevation-height
#2
Tetsuya Sonoda, Takehiro Harada, Nobuyuki Yamamichi, Alberto Monje, Hom-Lay Wang
PURPOSE: Maxillary sinus augmentation via crestal approach has been advocated as an alternative approach for sinus membrane elevation. Presently, no study has examined the relationship between the amount of bone grafting material placed and the final sinus membrane elevation height. Therefore, the present study was aimed at investigating the extent of sinus membrane elevation height depending on the amount of bone grafting material inserted as well as three-dimensionally assessing the likelihood of membrane perforation during membrane elevation...
February 23, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28230603/computed-tomography-evaluation-of-nasal-bone-and-nasal-pyramid-in-the-turkish-population
#3
Hatice Kaplanoglu, Hüseyin Coskun, Ugur Toprak
OBJECTIVE: To classify shapes of the nasal bones in the Turkish population and comparatively evaluate the sizes of nasal bone and piriform apertures. METHODS: Two- and three-dimensional paranasal sinus computed tomography images of 363 patients were evaluated. Upper, intermediate, and inferior thickness of bilateral nasal bones and thickness of medial and lateral osteotomy line were measured. The shapes of the nasal bones were classified. RESULTS: The mean thickness of nasal bone in the study participants was 1...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28230588/how-to-expose-the-entire-sella-floor-with-minimal-manipulation-during-an-endoscopic-endonasal-transsphenoidal-approach
#4
Do Hyun Kim, Yong-Kil Hong, Sin-Soo Jeun, Yong Jin Park, Soo Whan Kim, Jin Hee Cho, Boo-Young Kim, Sung Won Kim
OBJECTIVE: A method of opening the posterior ethmoid air cells with minimal manipulation is important for adequate exposure of the sella floor and minimal nasal morbidity. METHODS: Between February 2009 and August 2016, 373 patients with skull-base tumors underwent surgery via endoscopic endonasal transsphenoidal approach with the 2-nostrils/4-hands technique using this technique. RESULTS: A linear incision was made laterally toward one-third of the superior turbinate along the superior border of the sphenoid sinus ostium...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28228944/semi-closed-surgical-technique-for-treatment-of-pilonidal-sinus-disease
#5
Georgios Sahsamanis, Stavros Samaras, Georgios Mitsopoulos, Titos Deverakis, Georgios Dimitrakopoulos, Dionysios Pinialidis
INTRODUCTION: Pilonidal sinus disease (PSD) is a highly debatable disorder regarding its surgical management, despite an assortment of surgical techniques described in the medical literature. The aim of this report is to provide an alternate semi-closed surgical method for treatment of PSD, with early recovery and a satisfactory cosmetic result. METHODS: In this retrospective study, 34 patients underwent surgical treatment for primary PSD; 32 male and 2 female. Patients were suffering from primary PSD, with the cyst located in the gluteal midline...
March 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28227158/interventional-placement-of-thin-coil-shaped-implants-powered-wirelessly-for-monitoring-vital-signals-and-controlling-abnormal-activities-by-electro-stimulation
#6
Hidetoshi Ohta, Masanobu Honda, Makoto Takamiya, Hidetoshi Ohta, Masanobu Honda, Makoto Takamiya, Masanobu Honda, Hidetoshi Ohta, Makoto Takamiya
Various types of implants are being commonly used for monitoring vital signals and controlling the critically ill patient's condition such as arrhythmia, sick sinus syndrome, etc. For implanting these medical devices under the skin, surgery is inevitable. These days many patients are more willing to accept interventional therapies that are less invasive, especially inserting a catheter into a blood vessel or endoscopy through a natural orifice. To be able to use interventional therapy for implanting medical devices, they will need to be small enough to fit them through a catheter or the forceps channel of an endoscope...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225836/analysis-of-immune-cell-populations-in-atrial-myocardium-of-patients-with-atrial-fibrillation-or-sinus-rhythm
#7
Natalia Smorodinova, Martin Bláha, Vojtěch Melenovský, Karolína Rozsívalová, Jaromír Přidal, Mária Ďurišová, Jan Pirk, Josef Kautzner, Tomáš Kučera
BACKGROUND: Atrial fibrillation (AF) is the most common arrhythmia and despite obvious clinical importance remains its pathogenesis only partially explained. A relation between inflammation and AF has been suggested by findings of increased inflammatory markers in AF patients. OBJECTIVE: The goal of this study was to characterize morphologically and functionally CD45-positive inflammatory cell populations in atrial myocardium of patients with AF as compared to sinus rhythm (SR)...
2017: PloS One
https://www.readbyqxmd.com/read/28219183/-how-to-predict-the-outcome-of-endoscopic-sinus-surgery-in-patients-with-chronic-sinusitis-with-nasal-polyps
#8
C S Wang, L Zhang
No abstract text is available yet for this article.
February 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28219166/-the-value-of-sinonasal-ct-scan-in-diagnosing-of-eosinophilic-chronic-rhinosinusitis-with-nasal-polyps
#9
Y F Meng, H F Lou, C S Wang, L Zhang
Objective: To compare the value of sinonasal CT scan with other clinical parameters in the pre-diagnosis of eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP). Methods: From January to May of 2016, One hundred and fifty consecutive CRSwNP patients (90 eCRSwNP and 60 non-eosinophilic CRSwNP) undergoing endoscopic functional sinus surgery in Beijing Tongren Hospital were recruited in this study. Preoperative CT scan, skin prick test (SPT) and oral fractional exhaled nitric oxide (FeNO) measurements were performed in each patient and full blood count with differential analysis was performed within 1 week before surgery...
February 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28218486/determinants-and-outcomes-of-upfront-surgery-versus-medical-therapy-for-chronic-rhinosinusitis-in-cystic-fibrosis
#10
Noel Ayoub, Andrew Thamboo, Al-Rahim Habib, Jayakar V Nayak, Peter H Hwang
BACKGROUND: The indications for surgical management of chronic rhinosinusitis (CRS) in patients with cystic fibrosis (CF) are poorly defined. In this study we compare outcomes of medical versus surgical treatment and examine trends associated with the transition from medical to surgical therapy in CF patients. METHODS: One hundred thirty-six patients with CF referred to a tertiary rhinology practice were retrospectively divided into 3 cohorts: Medical, Upfront Surgery, or Crossover, if they converted from medical to surgical management...
February 20, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28217380/parasagittal-meningiomas-our-surgical-experience-and-the-reconstruction-technique-of-the-superior-sagittal-sinus
#11
Alessandro Ricci, Hambra Di Vitantonio, Danilo De Paulis, Mattia Del Maestro, Massimo Gallieni, Soheila Raysi Dechcordi, Sara Marzi, Renato Juan Galzio
BACKGROUND: The radical resection of parasagittal meningiomas without complications and recurrences is the goal of the neurosurgeon. Nowadays, different managements are proposed. This study describes our surgical technique during the lesional excision and the reconstruction of the superior sagittal sinus (SSS). METHODS: The total removal (Simpson I and II) of parasagittal meningiomas (WHO grade I and II) was obtained in 75 patients from September 2000 to January 2010...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28215205/effectiveness-of-extensive-sinus-surgery-with-post-operative-medical-management-for-chronic-rhinosinusitis
#12
A J Wood, L Zhou, S Wilkinson, R G Douglas
OBJECTIVE: To prospectively assess treatment outcomes of chronic rhinosinusitis patients undergoing functional endoscopic sinus surgery and post-operative medical treatment over a prolonged follow-up period. METHODS: Patients undergoing functional endoscopic sinus surgery in the tertiary referral practice of a single surgeon were studied prospectively. Symptoms were scored by patients pre-operatively and over a minimum follow-up period of 12 months. RESULTS: The study comprised 200 non-consecutive patients...
February 20, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28214914/the-impact-of-bitter-taste-receptor-genetics-on-culturable-bacteria-in-chronic-rhinosinusitis
#13
D I Rom, J M Christensen, R Alvarado, R Sacks, R J Harvey
BACKGROUND: Extra-oral bitter taste receptors have been associated with innate bacterial defence mechanisms. Genetic variation in T2R38 functionality has been shown to be associated with susceptibility to upper respiratory tract infections and chronic rhinosinusitis (CRS). We sought to independently assess the influence of bitter taste receptor genotype on the presence of culturable bacteria in the sinuses. METHODOLOGY: A cross-sectional analysis of patients with CRS undergoing surgery was performed...
February 19, 2017: Rhinology
https://www.readbyqxmd.com/read/28213639/prechiasmatic-sulcus-and-optic-strut-an-anatomic-study-in-dry-skulls
#14
Vasiliki Kanellopoulou, Evgenia Efthymiou, Vasiliki Thanopoulou, Dimitra Kozompoli, Dimitrios Mytilinaios, Maria Piagkou, Elizabeth O Johnson
BACKGROUND: Although safe surgical access to the cavernous sinus is related to understanding the anatomical and ethnic variants of the prechiasmatic sulcus and the optic strut, there remains a paucity of studies of the morphology and the bony relationships in the region. The present study provides a systematic morphological and morphometric analysis of the sulcal region and the optic strut anatomy and their relations in a Greek population. METHODS: The interoptic distance, length of planum sphenoidale, sulcal length and sulcal angle was determined in 96 Greek adult dry skulls...
February 17, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28213192/trans-frontal-sinus-subcranial-approach-to-olfactory-groove-meningiomas-surgical-results-clinical-and-functional-outcome-in-a-consecutive-series-of-21-patients
#15
Lina Raffaella Barzaghi, Alfio Spina, Filippo Gagliardi, Nicola Boari, Pietro Mortini
BACKGROUND: The trans-frontal-sinus-subcranial approach (TFSSA) allows for direct exposure and removal of olfactory groove meningiomas (OGMs), without any brain retraction. Compared to other skull base approaches (like fronto-orbito-basal, transbasal, subcranial, fronto-orbito-zygomatic and one-and-half approach), it could offer the same advantages but it is less invasive. OBJECT: We report the results in a series of 21 consecutive patients harboring OGMs and operated through TFSSA, in order to propose a viable alternative approach...
February 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28212886/primary-ameloblastoma-of-the-temporal-bone
#16
Andro Košec, Jakov Ajduk, Mihael Ries, Robert Trotić
Ameloblastoma is a locally aggressive tumor derived from odontogenic epithelium. Although benign, its clinical behavior can often exhibit malignant characteristics. It is marked by slow and persistent growth with infiltration of adjacent tissues. Almost 70% occur in the mandible in patients older than 30 years. Recurrence of ameloblastoma from inadequate treatment is frequent. Because of its slow growth, recurrences can present decades after primary surgery. A primary ameloblastoma in an area outside the mandibular, maxillary, and infratemporal fossa regions has not been described in detail to date, with only 1 possible case mentioned in the literature...
January 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28212455/retrospective-analysis-of-dental-implants-placed-between-2012-and-2014-indications-risk-factors-and-early-survival
#17
Koenraad Grisar, Deepti Sinha, Joseph Schoenaers, Titiaan Dormaar, Constantinus Politis
PURPOSE: The aim of this study was to review the indications for implant placement, early outcomes, and associated risk factors. MATERIALS AND METHODS: A retrospective cohort study design was used. The study was composed of a group of 509 consecutive patients, which represented the total number of patients treated from 2012 to 2014 in the Department of Oral and Maxillofacial Surgery, University Hospitals Leuven, Belgium. The authors analyzed the indications for implant placement and the potential risk factors for early implant failure...
February 17, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28212129/endoscopic-removal-of-a-dental-implant-from-maxillary-sinus
#18
Serkan Dundar, Turgut Karlidag, Erol Keles
The displacement of a dental implant into the maxillary sinus during surgery or after a period of use is a complication defined in the dental implant clinical practice. This complication arises primarily from inadequate bone height and peri-implant infection. Specifically, foreign objects in the maxillary sinus can cause sinusitis via impaired mucociliary flow and foreign body reactions, so they must be removed. Caldwell-Luc, transnasal, and intraoral endoscopic sinus surgeries have all been used to remove such foreign bodies and lesions from maxillary sinuses...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28212125/functional-endoscopic-surgery-after-facial-trauma
#19
Marzia Petrocelli, Carolina Sbordone, Giovanni Salzano, Francesco Maria Cassandro, Giuseppe Chiarella, Alfonso Scarpa, Antonio Romano, Giorgio Iaconetta, Luigi Califano, Ettore Cassandro
The present study describes 3 patients of previous facial trauma who have subsequently been treated with functional endoscopic sinus surgery. The authors want pay attention on the possible correlation between facial trauma and sinusitis. Such fractures can be the cause of onset of paranasal sinusitis or of worsening of a previous sinusitis. The correlation between these 2 pathologies could be due to the fact that facial fractures concern the anatomic structures of paranasal sinuses. The damage to these structures during the facial trauma and tissue regeneration after injury or surgical treatment subverts the anatomy and function of the sinuses in a basically compromised situation...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28207598/newly-formed-bone-induced-by-recombinant-human-bone-morphogenetic-protein-2-a-histological-observation
#20
Azumi Hirata, Takaaki Ueno, Peter K Moy
PURPOSE: To observe, histologically, bone induced by recombinant human bone morphogenetic protein-2 (rhBMP-2) in onlay grafted and sinus lifted alveolaris. MATERIAL AND METHODS: Eighteen patients were treated with rhBMP-2 at concentration 1.5 mg/mL with an absorbable collagen sponge (ACS). The treated bone was harvested with small trephine bur at 5 or 7 months after surgery for the micro Computer Scanning (CT) and light microscopic observation. RESULTS: Micro CT showed clearly 3-dimensional trabecular bone structure...
February 14, 2017: Implant Dentistry
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