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https://www.readbyqxmd.com/read/28227604/non-invasive-heart-rate-monitoring-system-using-giant-magneto-resistance-sensor
#1
Kubera Kalyan, Vinit Kumar Chugh, C S Anoop, Kubera Kalyan, Vinit Kumar Chugh, C S Anoop, Vinit Kumar Chugh, Kubera Kalyan, C S Anoop
A simple heart rate (HR) monitoring system designed and developed using the Giant Magneto-Resistance (GMR) sensor is presented in this paper. The GMR sensor is placed on the wrist of the human and it provides the magneto-plethysmographic signal. This signal is processed by the simple analog and digital instrumentation stages to render the heart rate indication. A prototype of the system has been built and test results on 26 volunteers have been reported. The error in HR estimation of the system is merely 1 beat per minute...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226986/feasibility-study-of-a-giant-magneto-resistance-based-respiration-rate-monitor
#2
Vinit Kumar Chugh, Kubera Kalyan, C S Anoop, Vinit Kumar Chugh, Kubera Kalyan, C S Anoop, Kubera Kalyan, C S Anoop
This paper reports a simple and reliable electronic technique for the estimation of respiration rate (RR). Giant Magneto-Resistance (GMR) based sensors are employed to extract a plethysmograph signal from the subject. This signal is filtered and processed further through simple signal processing stages to obtain RR indication. The feasibility of the system has been studied on a prototype built and associated experimentation on 20 volunteers. The developed system provided clean plethysmographic signals, whose relevant features are shown to possess a relation with RR...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226651/comparison-of-pulse-rate-variability-and-heart-rate-variability-for-high-frequency-content-estimation
#3
R Logier, J De Jonckheere, A Dassonneville, M Jeanne, R Logier, J De Jonckheere, A Dassonneville, M Jeanne, A Dassonneville, J De Jonckheere, R Logier, M Jeanne
Heart Rate Variability (HRV) analysis can be of precious help in most of clinical situations because it is able to quantify the Autonomic Nervous System (ANS) activity. The HRV high frequency (HF) content, related to the parasympathetic tone, reflects the ANS response to an external stimulus responsible of pain, stress or various emotions. We have previously developed the Analgesia Nociception Index (ANI), based on HRV high frequency content estimation, which quantifies continuously the vagal tone in order to guide analgesic drug administration during general anesthesia...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222636/change-in-pulse-transit-time-in-the-lower-extremity-after-lumbar-sympathetic-ganglion-block-an-early-indicator-of-successful-block
#4
Eun-Young Joo, Yu Gyeong Kong, Jonghyuk Lee, Hyun-Seok Cho, Sung-Hoon Kim, Jeong Hun Suh
Objective To investigate the change in pulse transit time (PTT)-time between the electrocardiographic R wave and the highest point of the corresponding plethysmographic wave-after lumbar sympathetic ganglion block (LSGB) and evaluate PTT as an indicator of successful LSGB. Methods Sixteen cases of sympathetically mediated lower extremity neuropathic pain treated with LSGB were studied. Correlations between the changes in PTT and temperature were used to identify the cutoff point indicating successful LSGB. Results PTT rate of change at 5 min relative to the baseline PTT (dPTT5/PTT0) significantly correlated positively with the temperature change at 20 min (correlation coefficient 0...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28220077/noninvasive-assessment-of-the-effect-of-position-and-exercise-on-pulse-arrival-to-peripheral-vascular-beds-in-healthy-volunteers
#5
Yurie Obata, Qi J Ong, J T Magruder, Helen Grichkevitch, Dan E Berkowitz, Daniel Nyhan, Jochen Steppan, Viachaslau Barodka
Background: The effects of position and exercise on pulse wave distribution across a healthy, compliant arterial tree are not fully understood. We studied the effects of exercise and position on the pattern of pulse arrival times (PATs) in healthy volunteers. Moreover, we compared the pulse arrival time ratios to the respective distance ratios between different locations. Methods: Thirteen young healthy volunteers were studied, using an electrocardiogram and plethysmograph to simultaneously record pulse wave arrival at the ear lobe, index finger and big toe...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28153424/seizure-associated-central-apnea-in-a-rat-model-evidence-for-resetting-the-respiratory-rhythm-and-activation-of-the-diving-reflex
#6
S M Villiere, K Nakase, R Kollmar, J Silverman, K Sundaram, M Stewart
Respiratory derangements, including irregular, tachypnic breathing and central or obstructive apnea can be consequences of seizure activity in epilepsy patients and animal models. Periods of seizure-associated central apnea, defined as periods >1s with rapid onset and offset of no airflow during plethysmography, suggest that seizures spread to brainstem respiratory regions to disrupt breathing. We sought to characterize seizure-associated central apneic episodes as an indicator of seizure impact on the respiratory rhythm in rats anesthetized with urethane and given parenteral kainic acid to induce recurring seizures...
January 31, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28092917/is-fat-mass-accretion-of-late-preterm-infants-associated-with-insulin-resistance
#7
Nadia Liotto, Maria Lorella Giannì, Francesca Taroni, Paola Roggero, Chiara Cristiana Condello, Anna Orsi, Camilla Menis, Riccardo Bonfanti, Fabio Mosca
BACKGROUND: Late preterm infants show a major fat mass accretion from birth to term. The contribution of preterm birth to the development of the metabolic syndrome is still under investigation. OBJECTIVES: To evaluate body composition changes in late preterm infants during the first 3 months and to investigate their insulin sensitivity and resistance. METHODS: We conducted an observational, longitudinal study. A total of 216 late preterm infants underwent body composition assessment using an air displacement plethysmograph at term and at 3 months of corrected age...
January 17, 2017: Neonatology
https://www.readbyqxmd.com/read/28009638/the-effect-of-head-rotation-on-efficiency-of-face-mask-ventilation-in-anaesthetised-apnoeic-adults-a-prospective-randomised-crossover-study
#8
Taiga Itagaki, Jun Oto, Sara M Burns, Yandong Jiang, Robert M Kacmarek, Jeremi R Mountjoy
BACKGROUND: Upper airway obstruction occurs commonly after induction of general anaesthesia. It is the major cause of difficult mask ventilation. OBJECTIVES: The aim of this study was to determine whether head rotation improves the efficiency of mask ventilation of anaesthetised apnoeic adults. DESIGN: A prospective crossover study. SETTING: Single university teaching hospital. PATIENTS: Forty patients, aged 18 to 75 years with a BMI 18...
December 22, 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/27998692/squill-oxymel-a-traditional-formulation-from-drimia-maritima-l-stearn-as-an-add-on-treatment-in-patients-with-moderate-to-severe-persistent-asthma-a-pilot-triple-blind-randomized-clinical-trial
#9
Fatemeh Nejatbakhsh, Hossein Karegar-Borzi, Gholamreza Amin, Alireza Eslaminejad, Mostafa Hosseini, Mahbubeh Bozorgi, Mehrnaz Asadi Gharabaghi
ETHNOPHARMACOLOGICAL RELEVANCE: In Traditional Iranian Medicine (TIM), Squill (Drimia maritima (L.) Stearn) Oxymel was utilized in the treatment of asthma. Squill has been reported to exert anti-inflammatory, anti-oxidant, anti-cholinergic, and mucus secretion modulating effects. OBJECTIVE: This study aimed to make a preliminary evaluation of the efficacy and safety of an add-on Squill Oxymel treatment in patients with moderate to severe persistent asthma. METHODS: In a 6-week, triple-blind, randomized, placebo-controlled trial, 60 patients with stable moderate to severe persistent asthma were randomly allocated to receive either 10ml syrup of Squill Oxymel, simple oxymel, or a placebo 2 times a day, as an add-on to their routine treatment (inhaled corticosteroids and β2 agonists)...
January 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27989888/trpv4-antagonist-gsk2193874-does-not-modulate-cough-response-to-osmotic-stimuli
#10
Tomas Buday, Lea Kovacikova, Robert Ruzinak, Jana Plevkova
Osmolarity changes of airway superficial fluid are associated with cough and are used in research. TRPV4 is calcium channel initially described as osmosensor. In the airways, it can play role in increasing cough reflex sensitivity. The aim of our study was to test whether cough to osmotic stimuli is mediated via TRPV4 channel. Cough response was measured in 12 male guinea pigs by inhalation of saline, distilled water, hypertonic solution and citric acid for 10min in whole-body plethysmograph. Data were obtained in naïve animals and after pre-treatment with selective TRPV4 antagonist GSK2193874 in doses 300μg/kg (GSK300) and 900μg/kg (GSK900)...
February 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/27855687/diagnostic-accuracy-of-methacholine-challenge-tests-assessing-airway-hyperreactivity-in-asthmatic-patients-a-multifunctional-approach
#11
Richard Kraemer, Hans-Jürgen Smith, Thomas Sigrist, Gabi Giger, Roland Keller, Martin Frey
BACKGROUND: There are few studies comparing diagnostic accuracy of different lung function parameters evaluating dose-response characteristics of methacholine (MCH) challenge tests (MCT) as quantitative outcome of airway hyperreactivity (AHR) in asthmatic patients. The aim of this retrospectively analysis of our database (Clinic Barmelweid, Switzerland) was, to assess diagnostic accuracy of several lung function parameters quantitating AHR by dose-response characteristics. METHODS: Changes in effective specific airway conductance (sGeff) as estimate of the degree of bronchial obstruction were compared with concomitantly measured forced expiratory volume in 1 s (FEV1) and forced expiratory flows at 50% forced vital capacity (FEF50)...
November 17, 2016: Respiratory Research
https://www.readbyqxmd.com/read/27793099/severe-respiratory-changes-at-end-stage-in-a-fus-induced-disease-state-in-adult-rats
#12
Kasey L Jackson, Hemangini A Dhaibar, Robert D Dayton, Sergio G Cananzi, William G Mayhan, Edward Glasscock, Ronald L Klein
BACKGROUND: Fused in sarcoma (FUS) is an RNA-binding protein associated with the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration. ALS manifests in patients as a progressive paralysis which leads to respiratory dysfunction and failure, the primary cause of death in ALS. We expressed human FUS in rats to determine if FUS would induce ALS relevant respiratory changes to serve as an early stage disease indicator. The FUS expression was initiated in adult rats by way of an intravenously administered adeno-associated virus vector serotype 9 (AAV9) providing an adult onset model...
October 28, 2016: BMC Neuroscience
https://www.readbyqxmd.com/read/27776389/arterial-stiffness-in-patients-taking-second-generation-antipsychotics
#13
Ebru Fındıklı, Mustafa Gökçe, Vedat Nacitarhan, Mehmet Akif Camkurt, Hüseyin Avni Fındıklı, Selçuk Kardaş, Merve Coşgun Şahin, Mehmet Fatih Karaaslan
Objective: That treatment with second-generation antipsychotics (SGAs) causes metabolic side effects and atherosclerosis in patients with schizophrenia and bipolar disorder (BD) is well-known. Increased arterial stiffness is an important marker of arteriosclerosis and has been identified as an independent risk factor for cardiovascular diseases. We measured pulse wave velocity (PWV) as a marker of arteriosclerosis in patients with schizophrenia and BD who use SGAs. Methods: Patients and controls were collected from our psychiatry outpatient clinics or family medicine...
November 30, 2016: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27766656/comparison-of-arousal-and-preference-assessment-outcomes-for-sex-offenders-with-intellectual-disabilities
#14
Jorge R Reyes, Timothy R Vollmer, Astrid Hall
We compared outcomes of arousal and preference assessments for five adult male alleged sexual offenders with intellectual disabilities. Arousal assessments involved the use of the penile plethysmograph to measure changes in penile circumference to both deviant (males and females under the age of 18) and nondeviant (males and females over the age of 18) video clips. Paired-stimulus preference assessments were arranged to present still images from the video clips used in the arousal assessments. Results showed correspondence between the assessments for four out of the five participants...
October 20, 2016: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/27765750/ebselen-does-not-improve-oxidative-stress-and-vascular-function-in-patients-with-diabetes-a-randomized-crossover-trial
#15
Joshua A Beckman, Allison B Goldfine, Jane A Leopold, Mark A Creager
Oxidative stress is a key driver of vascular dysfunction in diabetes mellitus. Ebselen is a glutathione peroxidase mimetic. A single-site, randomized, double-masked, placebo-controlled, crossover trial was carried out in 26 patients with type 1 or type 2 diabetes to evaluate effects of high-dose ebselen (150 mg po twice daily) administration on oxidative stress and endothelium-dependent vasodilation. Treatment periods were in random order of 4 wk duration, with a 4-wk washout between treatments. Measures of oxidative stress included nitrotyrosine, plasma 8-isoprostanes, and the ratio of reduced to oxidized glutathione...
December 1, 2016: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/27756649/c57bl-6j-mouse-apolipoprotein-a2-gene-is-deterministic-for-apnea
#16
Carl B Gillombardo, Rebecca Darrah, Thomas E Dick, Michael Moore, Nathan Kong, Michael J Decker, Fang Han, Motoo Yamauchi, Mathias Dutschmann, Sausan Azzam, Kingman P Strohl
RATIONALE: Brainstem apolipoprotein AII (apoa2) mRNA expression correlates with apnea in breathing present in the adult C57Bl/6J (B6) sleep apnea model. OBJECTIVES: To test the hypothesis that the B6 apoa2 gene contributes to the trait, we performed plethysmographic testing in apoa2 knock out (KO: -/-) mice, an in situ brainstem-spinal cord preparation comparing KO to WT (+/+) mice, and B6xDBA recombinant inbred strains (RISs). MEASUREMENTS AND MAIN RESULTS: Apoa2 WT do, but KO and heterozygote (+/-) mice do not exhibit apnea during post-hypoxic breathing, measured in vivo...
January 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/27741074/using-pleth-variability-as-a-triage-tool-for-children-with-obstructive-airway-disease-in-a-pediatric-emergency-department
#17
Ariel Brandwein, Kavita Patel, Myriam Kline, Peter Silver, Sandeep Gangadharan
OBJECTIVES: Patients with obstructive airway disease have varying degrees of pulsus paradoxus that correlate with illness severity. Pulsus paradoxus can be measured using plethysmography. We investigated whether plethysmograph (pleth) variability on admission to the pediatric emergency department (ED) could predict patient disposition. We hypothesized that patients with a larger pleth variability would have a higher likelihood of being admitted to a general pediatrics unit or the intensive care unit (ICU)...
October 6, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27702883/internal-carotid-artery-blood-flow-in-healthy-awake-subjects-is-reduced-by-simulated-hypovolemia-and-noninvasive-mechanical-ventilation
#18
Maria Skytioti, Signe Søvik, Maja Elstad
Intact cerebral blood flow (CBF) is essential for cerebral metabolism and function, whereas hypoperfusion in relation to hypovolemia and hypocapnia can lead to severe cerebral damage. This study was designed to assess internal carotid artery blood flow (ICA-BF) during simulated hypovolemia and noninvasive positive pressure ventilation (PPV) in young healthy humans. Beat-by-beat blood velocity (ICA and aorta) were measured by Doppler ultrasound during normovolemia and simulated hypovolemia (lower body negative pressure), with or without PPV in 15 awake subjects...
October 2016: Physiological Reports
https://www.readbyqxmd.com/read/27687456/comparison-of-esophageal-doppler-and-plethysmographic-variability-index-to-guide-intraoperative-fluid-therapy-for-low-risk-patients-undergoing-colorectal-surgery
#19
Samantha R Warnakulasuriya, Simon J Davies, R Jonathan T Wilson, David R A Yates
STUDY OBJECTIVE: This study aims to investigate if there is equivalence in volumes of fluid administered when intravenous fluid therapy is guided by Pleth Variability Index (PVI) compared to the established technology of esophageal Doppler in low-risk patients undergoing major colorectal surgery. DESIGN: Randomized controlled trial. SETTING: Operating room. PATIENTS: Forty low-risk patients undergoing elective colorectal surgery...
November 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27679859/angiotensin-type-2-at-2-receptor-activation-reduces-renal-fibrosis-in-cyclosporine-nephropathy-evidence-for-blood-pressure-independent-effect
#20
Giovanna Castoldi, Cira R T di Gioia, Raffaella Carletti, Francesca Roma, Gianpaolo Zerbini, Andrea Stella
Compound 21 (C21), selective agonist of AT2 receptors, shows antinflammatory effects in hypertension and nephroprotection in diabetes. The aim of this study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized mainly by tubulo-interstitial fibrosis. Ten days before and during the experimental periods, low-salt diet was administered to Sprague Dawley rats. Cyclosporine-A (15mg/kg/day, i.p.) and cyclosporine-A plus C21 (0.3 mg/kg /day, i.p) were administered for 1 and 4 weeks...
September 27, 2016: Bioscience Reports
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