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Cholecystitis

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https://www.readbyqxmd.com/read/29340256/clinical-cholecystitis-in-the-absence-of-the-gallbladder
#1
Huda Naim, Syed Askari Hasan, Sameen Khalid, Aamer Abbass, Jason DSouza
The congenital absence of the gallbladder (CAG) is a rare condition with an incidence of 13-65 cases/ 100,000 in the general population. This occurs when the gallbladder and the cystic duct fail to bud from the common bile duct during the fifth week of gestation. Most commonly, the patients with congenital absence of the gallbladder are asymptomatic. When symptomatic, they present as biliary colic, dyspepsia, jaundice or very rarely as acute cholecystitis. We present a case of a 27-year-old female who presented with acute right upper quadrant abdominal pain...
November 10, 2017: Curēus
https://www.readbyqxmd.com/read/29334850/an-immunopathological-evaluation-of-the-porcine-cholecyst-matrix-as-a-muscle-repair-graft-in-a-male-rat-abdominal-wall-defect-model
#2
Dhanush Krishna Balakrishnan-Nair, Narayanan Divakaran Nair, Syam Kunnekkattu Venugopal, Vijayan Narayana Das, Sisilamma George, Mammen John Abraham, Saji Eassow, Malcolm Ronald Alison, Anoop Sainulabdeen, Thapasimuthu Vijayamma Anilkumar
With the increasing use of animal-based biomaterials for regenerative medical applications, the need for their safety assessment is paramount. A porcine cholecyst-derived scaffold (CDS), intended as a muscle repair graft, prepared by a nondetergent/enzymatic method was engrafted in a rat abdominal wall defect model. Host tissue-scaffold interface samples were collected 2, 8, and 16 weeks postimplantation and evaluated by histopathology, immunohistochemistry, and electron microscopy. The nature of the tissue reaction was compared with those induced by a jejunum-derived scaffold (JDS) prepared by the same method and a commercial-grade small intestinal submucosa (CSIS) scaffold...
January 1, 2018: Toxicologic Pathology
https://www.readbyqxmd.com/read/29334699/tokyo-guidelines-2018-updated-tokyo-guidelines-for-the-management-of-acute-cholangitis-acute-cholecystitis
#3
EDITORIAL
Tadahiro Takada
No abstract text is available yet for this article.
January 2018: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/29330979/early-versus-delayed-laparoscopic-cholecystectomy-for-acute-cholecystitis
#4
Sadaf Khalid, Zahid Iqbal, Afsar Ali Bhatti
BACKGROUND: Laparoscopic cholecystectomy is considered the gold standard for the management of acute cholecystitis but controversy surrounds the timings of the surgery. Studies are available favouring both early and delayed laparoscopic cholecystectomy. The objective of this study was to compare early versus delayed laparoscopic cholecystectomy for acute cholecystitis. METHODS: This quasi-experimental study included 180 patients irrespective of their age and sex presented at department of Surgery, Lahore General Hospital between January to December 2014 with a diagnosis of acute cholecystitis were assigned randomly to early laparoscopic cholecystectomy within 24 h of admission or to initial conservative treatment followed by delayed laparoscopic cholecystectomy, 6-12 weeks later...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29329599/gallbladder-ascariasis-in-kosovo-focus-on-ultrasound-and-conservative-therapy-a-case-series
#5
Vlora Ismaili-Jaha, Halim Toro, Lidvana Spahiu, Mehmedali Azemi, Teuta Hoxha-Kamberi, Muharrem Avdiu, Shqipe Spahiu-Konjusha, Luan Jaha
BACKGROUND: Ascaris lumbricoides is one of the most common intestinal infections in developing countries, including Kosovo. In contrast to migration to the bile duct, migration of the worm to the gallbladder, due to the narrow and tortuous nature of the cystic duct, is rare. When it does occur, it incites acalculous cholecystitis. CASE PRESENTATIONS: This case series describes a 16-month-old Albanian girl, a 22-month-old Albanian girl, a 4-year-old Albanian girl, and a 10-year-old Albanian boy...
January 13, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29325783/validation-of-the-aast-egs-acute-cholecystitis-grade-and-comparison-with-the-tokyo-guidelines
#6
Matthew Hernandez, Brittany Murphy, Johnathan M Aho, Nadeem N Haddad, Humza Saleem, Muhammad Zeb, David S Morris, Donald H Jenkins, Martin Zielinski
BACKGROUND: Acute cholecystitis presents with heterogeneous severity. The Tokyo Guidelines 2013 is a validated method to assess cholecystitis severity, but the variables are multifactorial. The American Association for the Surgery of Trauma (AAST) developed an anatomically based severity grading system for surgical diseases, including cholecystitis. Because the Tokyo Guidelines represent the gold standard to estimate acute cholecystitis severity, we wished to validate the AAST emergency general surgery scoring system and compare the performance of both systems for several patient outcomes...
January 8, 2018: Surgery
https://www.readbyqxmd.com/read/29320323/multimodality-imaging-including-dual-energy-ct-in-the-evaluation-of-gallbladder-disease
#7
Lisa Ratanaprasatporn, Jennifer W Uyeda, Jeremy R Wortman, Ian Richardson, Aaron D Sodickson
Imaging of the gallbladder has a key role in the examination of patients with abdominal pain-especially pain localized to the right upper quadrant. Pathologic conditions that affect the gallbladder include cholelithiasis and associated complications such as acute and chronic cholecystitis, choledocholithiasis, gallstone pancreatitis, and cancer. Modalities used to image the gallbladder include ultrasonography (US), computed tomography (CT), magnetic resonance (MR) imaging, and nuclear scintigraphy. US is the primary imaging modality used to evaluate entities suspected of being gallbladder disease, as it is both sensitive and specific for demonstrating gallstones, biliary duct dilatation, and inflammatory features...
January 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29319728/cholecystectomy-during-ceftriaxone-therapy-a-translational-study-with-a-new-rabbit-model
#8
Marcel Vasconcellos, Keren Cozer, Victor Senna Diniz, Wagner Baetas-da-Cruz, Manoel Luiz Ferreira, Paulo Cesar Silva, Alberto Schanaider
PURPOSE: To evaluate the actual incidence of both microlithiasis and acute cholecystitis during treatment with intravenous ceftriaxone in a new rabbit model. METHODS: New Zealand rabbits were treated with intravenous ceftriaxone or saline for 21 days. Ultrasound monitoring of the gallbladder was performed every seven days until the 21st day when histopathology, immunohistochemistry for proliferating cell nuclear antigen (PCNA), pro-caspase-3 and CD68, liver enzyme biochemistry, and chromatography analysis of the bile and sediments were also performed...
December 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29317948/colon-carcinoma-presenting-as-streptococcus-anginosus-bacteremia-and-liver-abscess
#9
Prashanth Rawla, Anantha R Vellipuram, Sathyajit S Bandaru, Jeffrey Pradeep Raj
A collection of dead white blood cells within the liver is called a liver abscess, and pyogenic liver abscess (PLA) is the most common type. PLA is commonly associated with biliary tract infections. However, in this case report, we present a rare cause of Streptococcus anginosus bacteremia and PLA which is associated with a carcinoma of the colon at the splenic flexure. The presentation mimicked a cholecystitis clinically, but the radio-imaging revealed a liver abscess. Blood cultures revealed an uncommon etiological agent, S...
December 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/29313288/mixed-adenoneuroendocrine-carcinoma-of-the-gallbladder
#10
Yi-Xin Lin, Qian-Bin Jia, Yi-Yun Fu, Nan-Sheng Cheng
Mixed adenoneuroendocrine carcinoma rarely occurs in the gallbladder. Most cases of cholecystic mixed adenoneuroendocrine carcinoma have been reported from Asia, North American, and Europe; however, there is scarce literature available on this tumor in other populations. Here, we report a case of mixed adenoneuroendocrine carcinoma in a Melanoderm woman who was initially suspected to have gallbladder cancer. No specific symptoms or abnormal blood test results were observed preoperatively. Magnetic resonance imaging revealed a 7-cm hypointense mass in the gallbladder fossa, which invaded the surrounding liver segments...
January 8, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29313126/an-observational-study-of-the-timing-of-surgery-use-of-laparoscopy-and-outcomes-for-acute-cholecystitis-in-the-usa-and-uk
#11
A C Murray, S Markar, H Mackenzie, O Baser, T Wiggins, A Askari, G Hanna, O Faiz, E Mayer, C Bicknell, A Darzi, R P Kiran
BACKGROUND: Evidence supports early laparoscopic cholecystectomy for acute cholecystitis. Differences in treatment patterns between the USA and UK, associated outcomes and resource utilization are not well understood. METHODS: In this retrospective, observational study using national administrative data, emergency patients admitted with acute cholecystitis were identified in England (Hospital Episode Statistics 1998-2012) and USA (National Inpatient Sample 1998-2011)...
January 8, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29312740/serum-metalloproteinase-2-and-tissue-inhibitor-of-metalloproteinase-2-in-lung-carcinoma-patients
#12
Magdalena Drzewiecka-Jędrzejczyk, Rafał Wlazeł, Monika Terlecka, Sławomir Jabłoński
Background: Assessment of serum extracellular matrix (ECM) metalloproteinase MMP-2 and tissue inhibitor of matrix metalloproteinase TIMP-2 concentrations in non-small cell lung carcinoma (NSCLC) patients considering TNM staging. Assessment of the prognostic value of MMP-2 and TIMP-2 concentrations in NSCLC patients. Methods: The study group consisted of 81 NSCLC patients (24 females and 57 males) aged 46 to 86 years (mean age of 67±8.2 years). The control group comprised 39 randomly selected patients (20 females and 19 males) aged 27 to 73 years (mean age of 47±15...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29307148/panparietal-cholesterolosis-xantho-granulomatous-cholecystitis-precursor
#13
Adriana Handra-Luca
No abstract text is available yet for this article.
March 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29305364/postsurgical-pyoderma-gangrenosum-after-an-autologous-stem-cell-transplantation-for-multiple-myeloma
#14
Maria Cecilia Borges Bittencourt, Marcelo Junqueira Atanazio, Erick Menezes Xavier, Silvia Figueiredo Costa
We report a man who underwent autologous stem cell transplantation (ASCT) for multiple myeloma. Two months after ASCT, he presented with necrotising cholecystitis due to gallbladder stones and was submitted to laparoscopic cholecystectomy. About a week later, he developed progressive skin ulcers at sites where trochanters had been inserted. Progressive enlargement and necrotic aspect of these ulcers took place despite debridement and large spectrum antibiotics. New ulcers developed at the site of enoxaparin injection at the right arm (pathergy phenomenon)...
January 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29303882/inflammation-based-prognostic-scores-predict-disease-severity-in-patients-with-acute-cholecystitis
#15
Noriko Sato, Akiyoshi Kinoshita, Nami Imai, Takafumi Akasu, Takeharu Yokota, Akira Iwaku, Kazuhiko Koike, Masayuki Saruta
BACKGROUND: Although several investigators have reported that inflammation-based prognostic scores can predict disease severity in patients with various inflammatory diseases, whether or not these scores are associated with disease severity in patients with acute cholecystitis (AC) has not yet been fully clarified. PATIENTS AND METHODS: Two hundred and sixty-two patients with AC were reviewed retrospectively. We evaluated the correlations between demographic or clinical variables, including the neutrophil-to-lymphocyte ratio (NLR), the Glasgow Prognostic Score (GPS), the modified Glasgow Prognostic Score (mGPS), and the C-reactive protein/albumin (CRP/Alb) ratio, as well as the disease severity grade on the basis of the revised Tokyo guidelines...
January 4, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29286615/epcam-based-flow-cytometric-detection-of-circulating-tumor-cells-in-gallbladder-carcinoma-cases
#16
Namrata Punit Awasthi, Swati Kumari, Azfar Neyaz, Sameer Gupta, Akash Agarwal, Ashish Singhal, Nuzhat Husain
Purpose: Liquid biopsy has entered the arena of cancer diagnostics in the past decade and detection of circulating tumor cells (CTC) is one diagnostic component. CTCs in gallbladder cancer (GBC) have hitherto not been comprehensively analysed. Methods and Results: The current study focused on the diagnostic role of CTCs in 27 cases of treatment-naive GBC and 6 normal controls as well as 6 cases of cholecystitis. An EasySep kit featuring negative immunomagnetic bead separation and flow cytometric detection of EpCAM positive and CD45 negative cells revealed CTCs in 25 of the 27 cases...
December 29, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29286503/population-morbidity-in-the-zaporizhzhia-nuclear-power-plant-observation-zone-as-an-integral-part-of-public-health
#17
I M Khomenko, N V Zakladna, N M Orlova
OBJECTIVE: To evaluate the health status of adult population living in the Ukrainian nuclear power industry obser vation zone on the example of Zaporizhzhia Nuclear Power Plant. MATERIALS AND METHODS: System review, analytic, sociological survey and statistical methods. RESULTS: There was established an increase in the incidence of digestive diseases among adult population in Nikopol of Dnipropetrovsk region, which is included in the Zaporizhzhia NPP observation zone...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/29256914/indications-of-cholecystectomy-in-gallstone-disease
#18
Mark P Lamberts
PURPOSE OF REVIEW: Recent studies showed new insights in the indication and timing of cholecystectomy in gallstone disease. This review will provide an overview. RECENT FINDINGS: Considerable variations in indication for gallbladder surgery have been noticed leading to a significant number of unnecessary cholecystectomies. As a consequence, up to 33% of patients with uncomplicated symptomatic gallstone disease have persistent abdominal pain after cholecystectomy...
December 18, 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/29255548/-first-experience-with-outpatient-laparoscopic-cholecystectomy-in-tunisia
#19
Haithem Zaafouri, Skander Mrad, Nizar Khedhiri, Dhafer Haddad, Ahmed Bouhafa, Anis Ben Maamer
Introduction: Laparoscopic cholecystectomy is the gold standard treatment for symptomatic gallstones. There is some debate as to whether it should be performed in outpatient surgery or in one-day surgery to improve patient safety. This study aimed to evaluate the impact of laparoscopic cholecystectomy performed in outpatient surgery versus one-day surgery on standards such as mortality, serious adverse events and quality of life. Methods: We conducted a cross-sectional descriptive study in the Department of General Surgery at the Habib Thameur Hospital over the period May 2009-February 2010...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29238153/risk-factors-for-open-conversion-in-minimally-invasive-cholecystectomy
#20
Antonio Gangemi, Richard Danilkowicz, Francesco Bianco, Mario Masrur, Pier Cristoforo Giulianotti
Background and Objectives: Open conversion (OC) occurs in 5 to 10% of laparoscopic cholecystectomies (LCs) and results in suboptimal outcomes. Herein, we report our experience with OC in cholecystectomy performed with the minimally invasive (MIS) approach. Methods: Data from 960 minimally invasive cholecystectomies performed in the University of Illinois at Chicago (UIC) Division of General, Minimally Invasive, and Robotic Surgery were retrospectively compiled. Patient demographics and outcomes were analyzed for the major indicators that may predispose to OC...
October 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
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