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https://www.readbyqxmd.com/read/28930045/antibiotic-use-among-older-adults-on-an-acute-care-general-surgery-service
#1
André S Pollmann, Jon G Bailey, Philip J B Davis, Paul M Johnson
BACKGROUND: Antibiotics play an important role in the treatment of many surgical diseases that affect older adults, and the potential for inappropriate use of these drugs is high. Our objective was to describe antibiotic use among older adults admitted to an acute care surgical service at a tertiary care teaching hospital. METHODS: Detailed data regarding diagnosis, comorbidities, surgery and antibiotic use were retrospectively collected for patients 70 years and older admitted to an acute care surgical service...
October 1, 2017: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/28928930/sterile-abscess-mimicking-an-abdominal-tumor-8-years-after-laparoscopic-cholecystectomy
#2
Diganta Kakaty, Jlonca Gosztonyi, Chloe Anthamatten, Roland Zengaffinen
Spillage of gallstones (6-40%) are common during laparoscopic cholecystectomy. Development of intraperitoneal and perihepatic abscesses are relatively rare (<0.1%). However, it may pose a diagnostic dilemma mimicking intra-abdominal tumor due to their similar radiologic appearance. CASE REPORT: We present a 57-year-old woman with history of cholecystectomy 8 years prior who presented with a suspected diagnosis of incarcerated port site hernia with associated radiological evidence of an intra-abdominal tumor...
September 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28928424/genome-characterization-of-two-bile-isolated-vibrio-fluvialis-strains-an-insight-into-pathogenicity-and-bile-salt-adaption
#3
Beiwen Zheng, Xiawei Jiang, Hong Cheng, Lihua Guo, Jing Zhang, Hao Xu, Xiao Yu, Chen Huang, Jinru Ji, Chaoqun Ying, Youjun Feng, Yonghong Xiao, Lanjuan Li
Vibrio fluvialis is recognized as an emerging pathogen. However, not much is known about the mechanism of its pathogenesis, and its adaptation to a special niche such as the gall bladder. Here we describe two V. fluvialis strains that cause acute cholecystitis. It is noteworthy that both strains were susceptible to all antibiotics tested, which is in contrast to previous studies, suggesting substantial genetic diversity among V. fluvialis isolates. In agreement with their survival and growth in the gall bladder, the genomes of strains 12605 and 3663 contain a considerable number of genes that confer resistance to bile, including toxR, omp U, tolC, cmeABC, rlpB, yrbK, rpoS, damX and gltK...
September 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28916859/near-infrared-cholecystocholangiography-with-direct-intragallbladder-indocyanine-green-injection-preliminary-clinical-results
#4
Yu-Yin Liu, Chien-Hung Liao, Michele Diana, Shang-Yu Wang, Seong-Ho Kong, Chun-Nan Yeh, Bernard Dallemagne, Jacques Marescaux, Ta-Sen Yeh
BACKGROUND: Near-infrared (NIR) fluorescence cholangiography by systemic administration of indocyanine green (ICG) enhances the visualization of the biliary tree anatomy. However, the simultaneous enhancement of liver parenchyma can disturb the visualization of critical details. We herein proposed a new technique of NIR cholecystocholangiography by intragallbladder ICG injection to increase the safety during laparoscopic cholecystectomy. METHODS: A total of 46 patients scheduled for laparoscopic cholecystectomy for symptomatic lithiasis (n = 21) or cholecystitis (n = 25) were enrolled...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28914831/-technical-features-of-laparoscopic-cholecystectomy-in-patients-with-overweight-and-obesity
#5
I V Mikhin, А А Vorobiyov, M B Doronin, O A Kosivtsov, L A Ryaskov
AIM: To improve surgical treatment of patients with cholelithiasis and obesity by using of different technologies of laparoscopic cholecystectomy. MATERIAL AND METHODS: There were 88 (16.4%) patients with overweight and obesity among 538 patients who underwent laparoscopic cholecystectomy. Conventional laparoscopic cholecystectomy was performed in 33 (6.1%) cases, cholecystectomy through single laparoscopic access - in 12 (2.3%), cholecystectomy via single laparoscopic access with trocar support - in 43 (8...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28914830/-combined-forecasting-system-of-peritonitis-outcome
#6
N V Lebedev, A E Klimov, S B Agrba, E K Gaidukevich
AIM: To create a reliable system for assessing of severity and prediction of the outcome of peritonitis. MATERIAL AND METHODS: Critical analysis of the systems for peritonitis severity assessment is presented. The study included outcomes of 347 patients who admitted at the Department of Faculty Surgery of Peoples' Friendship University of Russia in 2015-2016. The cause of peritonitis were destructive forms of acute appendicitis, cholecystitis, perforated gastroduodenal ulcer, various perforation of small and large intestines (including tumor)...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28913619/bile-duct-obstruction-in-a-patient-treated-with-nivolumab-as-second-line-chemotherapy-for-advanced-non-small-cell-lung-cancer-a-case-report
#7
Jumpei Kashima, Yusuke Okuma, Ryoko Shimizuguchi, Kazuro Chiba
Immune checkpoint inhibitors (ICIs) are becoming a standard therapy for non-small-cell lung cancer in the advanced stage. As these ICIs become widely available in clinical practice, immune-related adverse effects will become more common. Here we report a patient with lung adenocarcinoma who was treated with nivolumab and developed obstruction because of biliary inflammation. A 63-year-old Japanese man having lung adenocarcinoma with pleural dissemination complained of epigastric pain on the fifth cycle of nivolumab...
September 14, 2017: Cancer Immunology, Immunotherapy: CII
https://www.readbyqxmd.com/read/28913118/the-course-and-outcomes-of-complicated-gallstone-disease-in-pregnancy-experience-of-a-tertiary-center
#8
Mehmet İlhan, Gülşah İlhan, Ali Fuat Kaan Gök, Kayıhan Günay, Cemalettin Ertekin
OBJECTIVE: To evaluate the course and outcomes of pregnant patients with complicated gallstone disease and to reveal the experience of a tertiary center. MATERIALS AND METHODS: The records of 92.567 patients were evaluated using searches for diagnoses with the terms of pregnant, pregnancy, gallstone, cholecystitis, cholangitis, choledocholithiasis, pancreatitis, and endoscopic retrograde cholangiopancreatography in pregnancy in the hospital database. Patients' age, week of gestation, parity, body mass index, definitive diagnosis, attack episodes, treatment modalities, and obstetric and neonatal complications were evaluated...
December 2016: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28912916/acute-liver-failure-in-a-patient-travelling-from-asia-the-other-face-of-the-coin-of-infectious-disease
#9
Balen Abdulrahman, Mohamed H Ahmed, John Ramage
We present a case of a 63-year-old male who had travelled from South India to United Kingdom (UK) visiting relatives. He had developed episodes of diarrhea, vomiting and fevers while travelling and on assessment in hospital, mild abdominal distension was noted with rapid deterioration to hypovolemic shock. Initial blood test showed a low platelet count with deranged liver function tests (LFTs). It was noted that during admission to intensive care unit (ICU), blood continued to ooze from a previous surgical laparoscopy wound, central and arterial line access sites...
August 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28906420/outcomes-of-consistent-conservative-management-for-acute-cholecystitis-followed-by-delayed-cholecystectomy
#10
Shohei Komatsu, Shinobu Tsuchida, Tomoyuki Wakahara, Nozomi Ueno, Akihiro Toyokawa, Akihiko Watanabe, Atsushi Sugahara, Hidekazu Mukai
OBJECTIVE: This study's objective was to assess outcomes of a totally conservative strategy for acute cholecystitis (AC) followed by delayed elective cholecystectomy. PATIENTS AND METHODS: Consecutive patients who underwent cholecystectomy for AC were divided into the Emergent and Elective cholecystectomy groups. Patients in the elective cholecystectomy group were divided into early, medium, and late groups according to time from symptoms onset. RESULTS: The success rate for conservative management reached 97...
September 12, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28905808/patient-with-metastatic-breast-cancer-presenting-as-acute-cholecystitis-with-one-year-survival-on-hormonotherapy
#11
Mateusz Zamkowski, Michał Kąkol, Wojciech Makarewicz, Jerzy Ropel, Maciej Bobowicz
Breast cancer has high metastatic potential with distant metastases involving mainly lungs, liver and bones. Less frequently it gives distant spread to other organs. Herein we would like to present a very rare case of an acute cholecystitis which turned out to be a metastatic breast cancer in previously healthy woman. A female patient, 64-years old, presented to the emergency department with symptoms of biliary colic and acute abdomen. During the emergency cholecystectomy, we diagnosed the gallbladder empyema with thickened wall...
August 31, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28900706/are-incidental-gallbladder-cancers-missed-with-a-selective-approach-of-gallbladder-histology-at-cholecystectomy
#12
Linda Lundgren, Carolina Muszynska, Axel Ros, Gunnar Persson, Oliver Gimm, Lars Valter, Bodil Andersson, Per Sandström
BACKGROUND: Incidental gallbladder cancer (IGBC) is an unexpected finding when a cholecystectomy is performed upon a benign indication, and the use of routine or selective histological analysis of gallbladder specimen is still debated. The aim of this study was to investigate whether the proportion of submitted gallbladder specimens for pathological investigation influences the proportion of IGBC found, and what possible factors preoperatively or perioperatively could influence the selection process...
September 12, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28892903/immunohistochemical-study-of-muc1-and-muc5ac-expression-in-gall-bladder-lesions
#13
Amit Bhoge, Siddhi Gaurish Sinai Khandeparkar, Avinash R Joshi, Bageshri Gogate, Maithili Mandar Kulkarni, Pallavi Bhayekar
INTRODUCTION: Immunohistochemical (IHC) markers of mucin family are associated with various Gallbladder Lesions (GBLs). AIM: To study the distribution of GBL with respect to age and sex as well as to analyse the IHC profile of MUC1 and MUC5AC in GBLs and attempt correlation with clinical and histopathological findings. MATERIALS AND METHODS: The present study was conducted over a period of six years. A technique of manual tissue array was employed for cases subjected to IHC using MUC1 and MUC5AC...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28888080/tg18-management-strategies-for-gallbladder-drainage-in-patients-with-acute-cholecystitis-updated-tokyo-guidelines-2018-with-videos
#14
Yasuhisa Mori, Takao Itoi, Todd H Baron, Tadahiro Takada, Steven M Strasberg, Henry A Pitt, Tomohiko Ukai, Satoru Shikata, Yoshinori Noguchi, Anthony Yuen Bun Teoh, Myung-Hwan Kim, Horacio J Asbun, Itaru Endo, Masamichi Yokoe, Fumihiko Miura, Kohji Okamoto, Kenji Suzuki, Akiko Umezawa, Yukio Iwashita, Taizo Hibi, Go Wakabayashi, Ho-Seong Han, Yoo-Seok Yoon, In-Seok Choi, Tsann-Long Hwang, Miin-Fu Chen, O James Garden, Harjit Singh, Kui-Hin Liau, Wayne Shih-Wei Huang, Dirk Joan Gouma, Giulio Belli, Christos Dervenis, Eduardo de Santibañes, Mariano Eduardo Giménez, John Albert Windsor, Wan Yee Lau, Daniel Cherqui, Palepu Jagannath, Avinash Nivritti Supe, Keng-Hao Liu, Cheng-Hsi Su, Daniel J Deziel, Xiao-Ping Chen, Sheung Tat Fan, Chen-Guo Ker, Eduard C Jonas, Robert Padbury, Shuntaro Mukai, Goro Honda, Atsushi Sugioka, Koji Asai, Ryota Higuchi, Keita Wada, Masahiro Yoshida, Toshihiko Mayumi, Koichi Hirata, Yoshinobu Sumiyama, Kazuo Inui, Masakazu Yamamoto
Since the publication of the Tokyo Guidelines in 2007 and their revision in 2013, appropriate management for acute cholecystitis has been more clearly established. Since the last revision, several manuscripts, especially for alternative endoscopic techniques, have been reported; therefore, additional evaluation and refinement of the 2013 Guidelines is required. We describe a standard drainage method for surgically high-risk patients with acute cholecystitis and the latest developed endoscopic gallbladder drainage techniques described in the updated Tokyo Guidelines 2018 (TG18)...
September 9, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28883294/potential-risk-factors-for-postoperative-complications-and-deaths-after-laparoscopic-cholecystectomy-in-the-elderly
#15
Manabu Sato, Koujin Endo, Akihiko Harada, Shinichi Yabuuchi
Laparoscopic cholecystectomy (LC) is performed for gallbladder stones and cholecystitis in a large number of elderly patients. However, the safety of LC in the elderly is questioned. The aim of this study was to investigate predictive factors for the incidence of postoperative complications and deaths after LC in patients aged 80 years and older. Data from 85 elderly patients who underwent LC between January 2005 and December 2015 were prospectively collected in a database at our hospital. The following factors were compared for the occurrence of postoperative complications and deaths:age, gender, Body Mass Index, laboratory date, severity grade of cholecystitis, comorbidity of choledocholithiasis, conversion to open cholecystectomy, early or delayed LC, amount of time from onset to LC, operative duration, blood loss, and the following scoring systems for predicting risk of surgery:ECOG-PS, ASA, SIRS, CONUT, POSSUM, SAS, E-PASS...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/28881393/outcomes-of-gallstone-disease-during-pregnancy-a-population-based-data-linkage-study
#16
Ibinabo Ibiebele, Margaret Schnitzler, Tanya Nippita, Jane B Ford
BACKGROUND: Gallstone disease is a leading indication for non-obstetric abdominal surgery during pregnancy. There are limited whole population data on maternal and neonatal outcomes. This population-based study aims to describe the outcomes of gallstone disease during pregnancy in an Australian setting. METHODS: Linked hospital, birth, and mortality data for all women with singleton pregnancies in New South Wales, Australia, 2001-2012 were analysed. Exposure of interest was gallstone disease (acute biliary pancreatitis, gallstones with/without cholecystitis)...
September 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28880815/effects-of-a-national-smoking-ban-on-hospital-admissions-for-cardiovascular-diseases-a-time-series-analysis-in-taiwan
#17
Yue-Nin Yang, Yu-Tung Huang, Chun-Yuh Yang
On January 11, 2009, a comprehensive smoking ban was implemented in Taiwan. The aim of this study was to evaluate the effect of this ban on hospital admissions for ischemic heart disease (IHD). Trends in the country-level monthly hospital admission rates for IHD were determined and frequency compared to other conditions such as control conditions cholecystitis, bowel obstruction, and appendicitis from January 1997 (1 year before the first phase of smoke-free laws was implemented) to December 2012 (3 years after the second phase of the ban)...
September 7, 2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28877816/synchronous-acute-appendicitis-and-acute-cholecystitis-a-discussion-of-a-century-s-worth-of-epidemiologic-basic-science-and-clinical-research-explicating-the-pathophysiology-of-a-likely-underrecognized-historical-condition
#18
Ehyal Shweiki, Thea P Price, Pankaj H Patel, George J Koenig, Alec C Beekley, David W Rittenhouse, Kris R Kaulback, Murray J Cohen
No abstract text is available yet for this article.
November 1, 2016: American Surgeon
https://www.readbyqxmd.com/read/28876646/incidental-gallbladder-cancer-the-first-report-from-sub-saharan-africa
#19
Z A Khan, M B Brand
BACKGROUND: Incidental gallbladder cancer (iGBC) is found in 0.3-1.5% of cholecystectomy specimens. GBC is uncommon with significant variation amongst geographical regions and ethnic groups. Less than 100 GBC's have been reported in sub Saharan Africa, hence the need for this national audit in South Africa. METHOD: National data was obtained from the South African NHLS for 2003-2015. 34 294 cholecystectomy specimens were included of which 239 were GBCs; 135 were iGBC...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28874618/cholecystectomy-in-emilia-romagna-region-italy-a-retrospective-cohort-study-based-on-a-large-administrative-database
#20
Fausto Catena, Rita Maria Melotti, Daniel Louis, Daniela Fortuna, Luca Ansaloni, Federico Coccolini, Salomone Di Saverio, Massimo Sartelli, Antonio Tarasconi, Gianluca Baiocchi, Nazario Portolani, Josephine Napoli, Belinda De Simone, Rodolfo Catena, Rossana De Palma
BACKGROUND: The aim of this study was to ascertain the variability and to identify a trend for the outcome of cholecystectomy surgery when used to treat cholelithiasis and acute cholecystitis. METHODS: This was a large retrospective cohort study following patients up to 11 years post surgery, based on administrative data collected from 2002 to 2012 in the Emilia-Romagna Region (Northern Italy) and comparing the effectiveness and efficiency of surgical activity (laparoscopic (LC) and open cholecystectomy (OC))...
2017: Annali Italiani di Chirurgia
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