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Tinea infections

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https://www.readbyqxmd.com/read/29649923/diffuse-dermatophytosis-occurring-on-dimethyl-fumarate-therapy
#1
Jeffrey I Greenstein
BACKGROUND: Opportunistic infections have occurred during dimethyl fumarate (DMF) therapy. OBJECTIVE: Diffuse skin dermatophytosis which occurred during DMF therapy in the setting of lymphopenia is described. METHODS AND RESULTS: The clinical course, the lymphocyte subset profile, and dermatologic evaluations were reviewed. In both instances, there was no other cause of lymphopenia or immune suppression, and it is likely that the tinea infections are associated with DMF therapy...
April 1, 2018: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29644192/is-antifungal-resistance-a-cause-for-treatment-failure-in-dermatophytosis-a-study-focused-on-tinea-corporis-and-cruris-from-a-tertiary-centre
#2
Kabir Sardana, Ravinder Kaur, Pooja Arora, Ritu Goyal, Sneha Ghunawat
Background: Dermatophytoses are one of the most common skin diseases that have been largely simple to treat. However, in recent years, these infections have become recalcitrant to treatment which can possibly be due to antifungal resistance. Aim: To analyze the resistance pattern of patients with recalcitrant dermatophytoses. Materials and Methods: A cross-sectional evaluation was undertaken of 40 consecutive patients with recalcitrant tinea corporis/cruris/both who had taken systemic antifungal treatment and did not respond completely to therapy or had recurrent lesion within 1 month of stopping the therapy...
March 2018: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29601494/the-burden-of-serious-fungal-infections-in-cameroon
#3
Christine E Mandengue, David W Denning
Fungal infections are frequent in Cameroon, and invasive fungal infections are sometimes detected, usually in HIV-infected patients. For these reasons, we have estimated the burden of fungal infections. Using published literature and population estimates for the at-risk group, we used deterministic modelling to derive national incidence and prevalence estimates for the most serious fungal diseases. HIV infection is common and an estimated 120,000 have CD4 counts <200 × 10⁶/mL and commonly present with opportunistic infection...
March 30, 2018: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29600810/tinea-pedis-acquired-in-mosques
#4
REVIEW
Stefano Veraldi, Luigi Esposito, Alberto Gorani
Interdigital tinea pedis is a mycotic infection of the feet which occurs mainly in adult males. The transmission is due to repeated contacts with the soil. In Italy, Trichophyton rubrum, T. mentagrophytes (including T. mentagrophytes var. interdigitale) and Epidermophyton floccosum are the most frequently involved species. Interdigital tinea pedis is characterized clinically by maceration, erythema, vesicles, scales, crusts, erosions and ulcers located at the 2nd , 3rd and 4th interdigital folds. Interdigital tinea pedis may be asymptomatic; however, when erosions and ulcers occur, the patients may complain of pruritus, burning sensation and pain...
March 30, 2018: Mycoses
https://www.readbyqxmd.com/read/29577447/high-terbinafine-resistance-in-trichophyton-interdigitale-isolates-in-delhi-india-harbouring-mutations-in-the-squalene-epoxidase-sqle-gene
#5
Ashutosh Singh, Aradhana Masih, Ananta Khurana, Pradeep Kumar Singh, Meenakshi Gupta, Ferry Hagen, Jacques F Meis, Anuradha Chowdhary
In the last few years infections caused by dermatophytes along with a concomitant increase in the number of difficult to treat cases has increasingly been recognized indicating that dermatophytosis remains a challenging public health problem. The majority of infections are caused by Trichophyton rubrum and T. mentagrophytes complex. Terbinafine, an allylamine antifungal used orally and topically is considered to be a first-line drug in the therapy of dermatophyte infections. Terbinafine resistance has been predominately attributed to point mutations in the squalene epoxidase (SQLE) target gene a key enzyme in the ergosterol biosynthetic pathway leading to single amino acid substitutions...
March 25, 2018: Mycoses
https://www.readbyqxmd.com/read/29573445/emergence-of-african-species-of-dermatophytes-in-tinea-capitis-a-17-year-experience-in-a-montreal-pediatric-hospital
#6
Danielle Marcoux, Julie Dang, Hedwige Auguste, Catherine McCuaig, Julie Powell, Afshin Hatami, Catherine Maari, Jean-Baptiste Le Meur
BACKGROUND/OBJECTIVES: An increase in dermatophyte infections caused by African species is reported in countries receiving African immigrants. Our goal was to determine the epidemiologic and clinical characteristics of tinea capitis in children infected with African species of dermatophytes in Montreal, Canada. METHODS: Demographic and clinical data from medical records of children infected with African species of dermatophytes were retrieved retrospectively (2000-2016) at Sainte-Justine University Hospital Center...
March 24, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29570867/an-outbreak-of-microsporum-canis-infection-at-a-military-base-associated-with-stray-cat-exposure-and-person-to-person-transmission
#7
Tal Brosh-Nissimov, Ronen Ben-Ami, Nadav Astman, Alex Malin, Yaron Baruch, Inbal Galor
BACKGROUND: Tinea corporis caused by Microsporum canis is usually associated with exposure to animals, but outbreaks with anthropophilic transmission were described. A large outbreak in a military base was investigated. OBJECTIVES: To investigate the outbreak's source and risk factors for infection in order to contain and eliminate it. PATIENTS/METHODS: All staff-members at the base were interviewed and examined. A case-control analysis of symptomatic patients was used to elucidate risk factors...
March 23, 2018: Mycoses
https://www.readbyqxmd.com/read/29557619/-tinea-capitis-by-microsporum-gypseum-an-infrequent-species
#8
Lidia García-Agudo, Jorge J Espinosa-Ruiz
Tinea capitis is considered the most frequent dermatophyte infection in children. The etiological agents vary from time to time and by geographical area, although they normally are zoophilic dermatophytes and in the last years also anthropophilic species. We report a clinical case of inflammatory tinea capitis in a 6-year-old child caused by Microsporum gypseum, a geophilic fungus pathogenic to humans and animals. The sources of human infection are soil, cats, dogs and small mammals. This species is less frequent as a cause of dermatophytosis in humans, described mainly in tinea corporis and rarely in tinea capitis...
April 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29552686/tinea-unguium-onychomycosis-caused-by-dermatophytes-a-ten-year-retrospective-study-2005-2014-in-a-tertiary-hospital-in-singapore
#9
Shiu Ming Pang, Jonathan Yi Yu Pang, Stephanie Fook-Chong, Ai Ling Tan
INTRODUCTION: Tinea unguium is a common nail infection. We conducted a retrospective ten-year study of the patient demographics and species distribution of dermatophytes causing tinea unguium in a tertiary hospital from Singapore. METHODS: Results of fungal nail cultures were retrieved from our hospital's microbiology department. Samples from nail scrapings and clippings were inoculated onto agar plates (Sabouraud dextrose agar with chloramphenicol and Mycosel agar)...
March 19, 2018: Singapore Medical Journal
https://www.readbyqxmd.com/read/29534500/burden-of-severe-fungal-infections-in-burkina-faso
#10
Sanata Bamba, Adama Zida, Ibrahim Sangaré, Mamoudou Cissé, David W Denning, Christophe Hennequin
Because of the limited access to more powerful diagnostic tools, there is a paucity of data regarding the burden of fungal infections in Burkina Faso. The aim of this study was to estimate the incidence and prevalence of serious fungal infections in this sub-Saharan country. We primarily used the national demographic data and performed a PubMed search to retrieve all published papers on fungal infections from Burkina Faso and its surrounding West African countries. Considering the prevalence of HIV infection (0...
March 11, 2018: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29484004/psoriasiform-dermatophytosis-in-a-bulgarian-child
#11
Anastasiya Atanasova Chokoeva, Uwe Wollina, Torello Lotti, Georgi Konstantinov Maximov, Ilia Lozev, Georgi Tchernev
Although tinea capitis is the most common fungal infection in children, significant changes have been reported in its epidemiology worldwide, as a result from certain geographic, climatic and cultural differences in one hand, as well as the changes in its etiologic pattern. The clinical manifestation of the infection and the stage of inflammation vary from mild desquamation to severe suppurative indurated plaques in kerion - like the pattern, depending on the nature of the etiologic agent and the host-immune response...
January 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29468277/-tinea-faciei-caused-by-nannizzia-persicolor-an-underdiagnosed-dermatophyte
#12
M Metzner, T Schwarz, J Brasch
We report on a tinea faciei caused by Nannizzia (N.) persicolor. The 4‑year-old boy had probably been infected by a guinea pig. Unambiguous infections caused by N. persicolor are rarely seen in Germany; however, this zoophilic and geophilic dermatophyte may only be rarely identified due to its resemblance to Trichophyton (T.) mentagrophytes. Therefore, the diagnostic attributes of N. persicolor and its differentiation from T. mentagrophytes are described. Particularly in case of contact with rodents, N...
February 21, 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29462232/treatment-of-signs-and-symptoms-pruritus-of-interdigital-tinea-pedis-with-econazole-nitrate-foam-1
#13
Lauren K Hoffman, Isabelle Raymond, Leon Kircik
BACKGROUND: Tinea pedis is the most common dermatophyte infection. Treatment is critical to alleviate pruritic symptoms, to reduce the risk for secondary bacterial infection, and to limit the spread of infection to other body sites or other individuals. The objective of this study was to compare the abilities of econazole nitrate topical foam, 1% and ketoconazole cream (2%) to reduce pruritus, thus improving quality of life, and to determine patient preference for the foam product versus the cream product in patients with interdigital tinea pedis...
February 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29459592/current-trends-of-using-systemic-antifungal-drugs-and-their-comparative-efficacy-in-tinea-corporis-and-tinea-cruris-in-outpatient-department-of-dermatology-in-a-tertiary-level-hospital
#14
T Sultana, S K Saha, M Hossain, S Ajmeri, M Sarker, M Sultana, A K Nandi, P K Das
Tinea corporis & cruris are one of the earliest known fungal infection and are very common throughout the world. Although tinea corporis and tinea cruris does not cause mortality but causes morbidity and poses a major health problem. This study was conducted to evaluate the Comparative Efficacy of Terbinafine and Fluconazole in the Treatment of Tinea corporis and Tinea cruris. This cross sectional comparative type of analytical study was carried out at the department of Pharmacology & Therapeutics with collaboration of Dermatology and Venereology in Mymensingh Medical College Hospital, Mymensingh, Bangladesh from January 2016 to December 2016...
January 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29447400/prevalence-and-clinical-correlation-of-superficial-fungal-foot-infection-in-thai-naval-rating-cadets
#15
Punyawee Ongsri, Sumanas Bunyaratavej, Charussri Leeyaphan, Penvadee Pattanaprichakul, Pattachee Ongmahutmongkol, Chulaluk Komoltri, Kanokvalai Kulthanan
Background: Superficial fungal foot infection is one of the most important dermatological diseases currently affecting military personnel. Many Thai naval rating cadets are found to suffer from superficial fungal foot infections and their sequels. Objective: To investigate prevalence, potent risk factors, responding pathogens and clinical correlation of superficial fungal foot infection in Thai naval rating cadets training in Naval rating school, Sattahip, Thailand...
February 13, 2018: Military Medicine
https://www.readbyqxmd.com/read/29439839/characterizing-the-clinical-isolates-of-dermatophytes-in-hamadan-city-central-west-of-iran-using-pcr-rlfp-method
#16
S Farokhipor, S A Ghiasian, H Nazeri, M Kord, M Didehdar
OBJECTIVE: Dermatophytosis is one of the most common mycotic infections, which considered as a public health problem in the major of countries. This study evaluated the molecular epidemiology of dermatophytosis in patients referred to Farshchian hospital in Hamadan city with PCR-RFLP method. MATERIALS AND METHODS: Four hundred and five specimens from clinically suspected patients of dermatophytosis were collected and analyzed by direct microscopic and culture. The isolates were identified by PCR-RFLP method using the MvaI restriction enzyme...
February 11, 2018: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/29437818/tinea-of-vellus-hair-a-diagnostic-and-therapeutic-challenge
#17
Thanadon Eksomtramage, Kumpol Aiempanakit
Tinea infection is a common superficial fungal infection of the skin, hair and nails. Tinea of vellus hair is a rare form of dermatophytosis that is difficult to diagnose and treat. Herein, the authors report the case of a patient who had an itchy rash on the cheek. Microscopic and mycological studies confirmed the diagnosis of tinea of vellus hair. The patient was treated with systemic antifungal therapy with clinical improvement. This report aims to describe an infrequent subtype of common disease and review clinical clues, tools for diagnosis as well as treatment plans...
February 8, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29433854/-dermatophytosis-due-to-trichophyton-violaceum-at-the-parasitology-mycology-laboratory-of-the-military-hospital-of-meknes-about-twelve-cases
#18
REVIEW
G Zoulati, R Y Maïga, M El Haouri, M Er-Rami
INTRODUCTION: Trichophyton violaceum is an anthropophilic dermatophyte, common in Mediterranean and African countries, which causes particularly trichophytic tinea in school-aged children. The objective of this work is to study the clinical and epidemiological profile of T. violaceum infections. MATERIAL AND METHODS: This is a descriptive retrospective study of a series of twelve cases of T. violaceum dermatophytosis diagnosed among patients referred to our laboratory for suspicion of dermatomycosis during a period from January 2011 to December 2016...
February 9, 2018: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/29388537/blad-containing-oligomer-a-novel-fungicide-used-in-crop-protection-as-an-alternative-treatment-for-tinea-pedis-and-tinea-versicolor
#19
Alexandra Carreira, João Boavida Ferreira, Iliana Pereira, João Ferreira, Paulo Filipe, Ricardo Boavida Ferreira, Sara Monteiro
PURPOSE: The lack of novel antifungal drugs and the increasing incidence and severity of fungal infections are major concerns worldwide. Herein, we tested the activity of the Blad-containing oligomer (BCO), a new antifungal molecule already in use for agriculture, on Malassezia spp. and dermatophytes, the causal agents of human tinea versicolor and tinea pedis. Given the lack of a standard method for Malassezia susceptibility testing and the plethora of published methods, we also developed an improved method for this genus...
February 2018: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29380297/epidemiology-of-fungal-infections-in-china
#20
REVIEW
Min Chen, Yuan Xu, Nan Hong, Yali Yang, Wenzhi Lei, Lin Du, Jingjun Zhao, Xia Lei, Lin Xiong, Langqi Cai, Hui Xu, Weihua Pan, Wanqing Liao
With the increasing number of immunocompromised hosts, the epidemiological characteristics of fungal infections have undergone enormous changes worldwide, including in China. In this paper, we reviewed the existing data on mycosis across China to summarize available epidemiological profiles. We found that the general incidence of superficial fungal infections in China has been stable, but the incidence of tinea capitis has decreased and the transmission route has changed. By contrast, the overall incidence of invasive fungal infections has continued to rise...
February 2018: Frontiers of Medicine
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