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https://www.readbyqxmd.com/read/28549446/-gnparser-a-powerful-parser-for-scientific-names-based-on-parsing-expression-grammar
#1
Dmitry Y Mozzherin, Alexander A Myltsev, David J Patterson
BACKGROUND: Scientific names in biology act as universal links. They allow us to cross-reference information about organisms globally. However variations in spelling of scientific names greatly diminish their ability to interconnect data. Such variations may include abbreviations, annotations, misspellings, etc. Authorship is a part of a scientific name and may also differ significantly. To match all possible variations of a name we need to divide them into their elements and classify each element according to its role...
May 26, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28546869/smoking-alcohol-and-drug-use-in-youth-and-adults-with-attention-deficit-hyperactivity-disorder
#2
Sydney Osland, Lauren Hirsch, Tamara Pringsheim
BACKGROUND: Previous research suggests a relationship between attention-deficit hyperactivity disorder (ADHD) and smoking, alcohol and illicit drug use, however most studies have focused on adolescents or young adults, or clinically ascertained samples. AIMS: To analyse population-based data on the relationship between ADHD and at-risk health behaviours in adolescents and adults. METHOD: Data were derived from a Statistics Canada population-based health survey...
May 2017: BJPsych Open
https://www.readbyqxmd.com/read/28545551/identifying-and-reducing-disparities-in-successful-addiction-treatment-completion-testing-the-role-of-medicaid-payment-acceptance
#3
Erick G Guerrero, Bryan R Garner, Benjamin Cook, Yinfei Kong, William A Vega, Lillian Gelberg
BACKGROUND: Medicaid has become the largest payer of substance use disorder treatment and may enhance access to quality care and reduce disparities. We tested whether treatment programs' acceptance of Medicaid payments was associated with reduced disparities between Mexican Americans and non-Latino Whites. METHODS: We analyzed client and program data from 122 publicly funded treatment programs in 2010 and 112 programs in 2013. These data were merged with information regarding 15,412 adult clients from both periods, of whom we selected only Mexican Americans (n = 7130, 46...
May 25, 2017: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/28542194/using-g6pd-tests-to-enable-the-safe-treatment-of-plasmodium-vivax-infections-with-primaquine-on-the-thailand-myanmar-border-a-cost-effectiveness-analysis
#4
Angela Devine, Minnie Parmiter, Cindy S Chu, Germana Bancone, François Nosten, Ric N Price, Yoel Lubell, Shunmay Yeung
BACKGROUND: Primaquine is the only licensed antimalarial for the radical cure of Plasmodium vivax infections. Many countries, however, do not administer primaquine due to fear of hemolysis in those with glucose-6-phosphate dehydrogenase (G6PD) deficiency. In other settings, primaquine is given without G6PD testing, putting patients at risk of hemolysis. New rapid diagnostic tests (RDTs) offer the opportunity to screen for G6PD deficiency prior to treatment with primaquine. Here we assessed the cost-effectiveness of using G6PD RDTs on the Thailand-Myanmar border and provide the model as an online tool for use in other settings...
May 24, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28541960/clinical-features-of-treated-and-untreated-type-1-idiopathic-macular-telangiectasia-without-the-occurrence-of-secondary-choroidal-neovascularization-followed-for-2-years-in-japanese-patients
#5
Rie Osaka, Chieko Shiragami, Aoi Ono, Mamoru Kobayashi, Yukari Takasago, Ayana Yamashita, Akitaka Tsujikawa
PURPOSE: To evaluate the clinical features of Type 1 idiopathic macular telangiectasia (IMT) followed up for 2 years. METHODS: Forty-nine patients with unilateral Type 1 IMT were examined. Thirty-one IMT eyes were treated with direct laser photocoagulation and/or intravitreal bevacizumab; the remaining 18 eyes, with good vision or slight macular edema, were untreated. Changes in best-corrected visual acuity and central retinal thickness between baseline and 24 months after the initial visit were examined...
May 24, 2017: Retina
https://www.readbyqxmd.com/read/28538024/effects-of-vilazodone-on-suicidal-ideation-and-behavior-in-adults-with-major-depressive-disorder-or-generalized-anxiety-disorder-post-hoc-analysis-of-randomized-double-blind-placebo-controlled-trials
#6
Michael E Thase, John Edwards, Suresh Durgam, Changzheng Chen, Cheng-Tao Chang, Maju Mathews, Carl P Gommoll
Treatment-emergent suicidal ideation and behavior are ongoing concerns with antidepressants. Vilazodone, currently approved for the treatment of major depressive disorder (MDD) in adults, has also been evaluated in generalized anxiety disorder (GAD). Post-hoc analyses of vilazodone trials were carried out to examine its effects on suicidal ideation and behavior in adults with MDD or GAD. Data were pooled from vilazodone trials in MDD (four studies) and GAD (three studies). The incidence of suicide-related events was analyzed on the basis of treatment-emergent adverse event reporting and Columbia-Suicide Severity Rating Scale (C-SSRS) monitoring...
May 19, 2017: International Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28535773/nurses-who-work-in-rural-and-remote-communities-in-canada-a-national-survey
#7
Martha L P MacLeod, Norma J Stewart, Judith C Kulig, Penny Anguish, Mary Ellen Andrews, Davina Banner, Leana Garraway, Neil Hanlon, Chandima Karunanayake, Kelley Kilpatrick, Irene Koren, Julie Kosteniuk, Ruth Martin-Misener, Nadine Mix, Pertice Moffitt, Janna Olynick, Kelly Penz, Larine Sluggett, Linda Van Pelt, Erin Wilson, Lela Zimmer
BACKGROUND: In Canada, as in other parts of the world, there is geographic maldistribution of the nursing workforce, and insufficient attention is paid to the strengths and needs of those providing care in rural and remote settings. In order to inform workforce planning, a national study, Nursing Practice in Rural and Remote Canada II, was conducted with the rural and remote regulated nursing workforce (registered nurses, nurse practitioners, licensed or registered practical nurses, and registered psychiatric nurses) with the intent of informing policy and planning about improving nursing services and access to care...
May 23, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28535713/the-relationship-between-shiftwork-and-violence-against-nurses-a-case-control-study
#8
Steve Sun, Susan Goodwin Gerberich, Andrew D Ryan
This study investigated the potential relationship between shiftwork and work-related physical assault (PA) against nurses who are at high risk of violence globally. Nurses (6,300), randomly selected from the licensing database and working in Minnesota, were surveyed regarding PA experiences. Through a nested case-control study, nurses who reported a PA in the previous 12 months and controls who were randomly selected from their assault-free working months, respectively, identified exposures experienced during the month prior to the assault month (cases) and the random non-PA months (controls)...
May 1, 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28533743/neonatal-hypoxia-ischaemia-mechanisms-models-and-therapeutic-challenges
#9
REVIEW
Lancelot J Millar, Lei Shi, Anna Hoerder-Suabedissen, Zoltán Molnár
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in human neonates, and is often associated with persistent motor, sensory, and cognitive impairment. Improved intensive care technology has increased survival without preventing neurological disorder, increasing morbidity throughout the adult population. Early preventative or neuroprotective interventions have the potential to rescue brain development in neonates, yet only one therapeutic intervention is currently licensed for use in developed countries...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28523743/applying-lessons-from-social-psychology-to-transform-the-culture-of-error-disclosure
#10
Jason Han, Denise LaMarra, Neha Vapiwala
CONTEXT: The ability to carry out prompt and effective error disclosure has been described in the literature as an essential skill among physicians that can lead to improved patient satisfaction, staff well-being and hospital outcomes. However, few studies have addressed the social psychology principles that may influence physician behaviour. METHODS: The authors provide an overview of recent administrative measures designed to encourage physicians to disclose error, but note that deliberate practice, buttressed with lessons from social psychology, is needed to implement further productive behavioural changes...
May 18, 2017: Medical Education
https://www.readbyqxmd.com/read/28509723/determinants-of-retinal-microvascular-features-and-their-relationships-in-two-european-populations
#11
Mirna Kirin, Reka Nagy, Thomas J MacGillivray, Ozren Polašek, Caroline Hayward, Igor Rudan, Harry Campbell, Sarah Wild, Alan F Wright, James F Wilson, Veronique Vitart
OBJECTIVES: To examine factors influencing retinal vasculature in two environmentally contrasted, cross-sectional studies of adult participants of European descent and to estimate the extent and specificity of genetic contributions to each retinal vasculature feature. METHODS: Retinal images from 1088 participants in the Orkney Complex Disease Study and 387 in the CROATIA-Korčula study, taken using the same nonmydriatic camera system and graded by the same person, were evaluated...
May 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28508222/lassa-virus-reverse-genetics
#12
Luis Martínez-Sobrido, Slobodan Paessler, Juan Carlos de la Torre
The Old World (OW) arenavirus Lassa (LASV ) is estimated to infect several hundred thousand people yearly in West Africa, resulting in high numbers of Lassa fever (LF), a viral hemorrhagic fever (HF) disease associated with high morbidity and mortality. To date, no licensed vaccines are available to LASV infections, and anti-LASV drug therapy is limited to an off-label use of ribavirin (Rib) that is only partially effective. The development of reverse genetics has provided investigators with a novel and powerful approach for the investigation of the molecular, cell biology, and pathogenesis of LASV...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28507771/association-between-suicidal-symptoms-and-repeat-suicidal-behaviour-within-a-sample-of-hospital-treated-suicide-attempters
#13
Derek P de Beurs, Claudia D van Borkulo, Rory C O'Connor
BACKGROUND: Suicidal behaviour is the end result of the complex relation between many factors which are biological, psychological and environmental in nature. Network analysis is a novel method that may help us better understand the complex association between different factors. AIMS: To examine the relationship between suicidal symptoms as assessed by the Beck Scale for Suicide Ideation and future suicidal behaviour in patients admitted to hospital following a suicide attempt, using network analysis...
May 2017: BJPsych Open
https://www.readbyqxmd.com/read/28507768/in-patient-suicide-selection-of-people-at-risk-failure-of-protection-and-the-possibility-of-causation
#14
Matthew Michael Large, Daniel Thomas Chung, Michael Davidson, Mark Weiser, Christopher James Ryan
BACKGROUND: Being a current psychiatric in-patient is one of the strongest statistical risk factors for suicide. It is usually assumed that this strong association is not causal but is a result of the combination of the selection of high-risk patients for admission and the imperfect protection from suicide afforded by psychiatric wards. Logically, a third factor, which is causal, might play a role in the association. It has recently been suggested that adverse experiences in psychiatric units such as trauma, stigma and loss of social role might precipitate some in-patient suicides...
May 2017: BJPsych Open
https://www.readbyqxmd.com/read/28505244/the-influence-of-maternally-derived-antibody-and-infant-age-at-vaccination-on-infant-vaccine-responses-an-individual-participant-meta-analysis
#15
Merryn Voysey, Dominic F Kelly, Thomas R Fanshawe, Manish Sadarangani, Katherine L O'Brien, Rafael Perera, Andrew J Pollard
Importance: The design of infant immunization schedules requires an understanding of the factors that determine the immune response to each vaccine antigen. Data Sources: Deidentified individual participant data from GlaxoSmithKline clinical trials were obtained through Clinical Study Data Request. The data were requested on January 2, 2015, and final data were received on April 11, 2016. Study Selection: Immunogenicity trials of licensed or unlicensed vaccines administered to infants were included if antibody concentrations in infants were measured prior to the first dose of vaccine...
May 15, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28504192/correlates-of-protection-for-enteric-vaccines
#16
Jan Holmgren, Umesh D Parashar, Stanley Plotkin, Jacques Louis, Su-Peing Ng, Eric Desauziers, Valentina Picot, Mitra Saadatian-Elahi
An immunological Correlate of Protection (CoP) is an immune response that is statistically interrelated with protection. Identification of CoPs for enteric vaccines would help design studies to improve vaccine performance of licensed vaccines in low income settings, and would facilitate the testing of future vaccines in development that might be more affordable. CoPs are lacking today for most existing and investigational enteric vaccines. In order to share the latest information on CoPs for enteric vaccines and to discuss novel approaches to correlate mucosal immune responses in humans with protection, the Foundation Mérieux organized an international conference of experts where potential CoPs for vaccines were examined using case-studies for both bacterial and viral enteric pathogens...
May 11, 2017: Vaccine
https://www.readbyqxmd.com/read/28501676/does-the-implementation-of-evidence-based-and-culturally-competent-practices-reduce-disparities-in-addiction-treatment-outcomes
#17
Erick G Guerrero, Bryan R Garner, Benjamin Cook, Yinfei Kong
RATIONALE: Research is limited on the extent to which implementation of evidence-based and culturally responsive practices reduces outcome disparities in substance use disorder treatment. We examined the role of contingency management treatment (CMT), medication-assisted treatment (MAT), and culturally competent practices on Mexican Americans' rate of successful completion of treatment. METHODS: We analyzed a concatenated dataset from 153 publicly funded substance use disorder treatment programs in Los Angeles County, California, in 2011 and 2013...
May 9, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28500447/-certification-guidelines-and-qualification-courses
#18
REVIEW
R Loose, M Wucherer
German regulations require a license for using ionizing radiation in medicine. This license-called "Fachkunde"-varies for different medical procedures such as CT, fluoroscopy, radiography, or mammography. The required frequencies and training times also vary for different medical disciplines such as radiology, cardiology, vascular surgery, traumatology, nuclear medicine, and radiotherapy, among others. The quality criteria for a specific license require a minimum training time under supervision and a minimum frequency of a wide range of procedures...
May 12, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28495813/trends-in-the-supply-of-california-s-emergency-departments-and-inpatient-services-2005-2014-a-retrospective-analysis
#19
Jessica L Chow, Matthew J Niedzwiecki, Renee Y Hsia
OBJECTIVES: Given increasing demand for emergency care, there is growing concern over the availability of emergency department (ED) and inpatient resources. Existing studies of ED bed supply are dated and often overlook hospital capacity beyond ED settings. We described recent statewide trends in the capacity of ED and inpatient hospital services from 2005 to 2014. DESIGN: Retrospective analysis. SETTING: Using California hospital data, we examined the absolute and per admission changes in ED beds and inpatient beds in all hospitals from 2005 to 2014...
May 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28494890/the-predictive-value-of-pre-recruitment-achievement-on-resident-performance-in-anesthesiology
#20
Fei Chen, Harendra Arora, Susan M Martinelli, Emily Teeter, David Mayer, David A Zvara, Anthony Passannante, Kathleen A Smith
STUDY OBJECTIVE: Selecting candidates for residency positions is challenging and there is little research on the correlation between commonly used selection criteria and subsequent performance in anesthesiology. This study examined the association between the selection measures and post-recruitment performance in residency. DESIGN: Retrospective review of archival data. SETTING: Anesthesiology residency program at a large academic anesthesiology department...
June 2017: Journal of Clinical Anesthesia
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