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https://www.readbyqxmd.com/read/28742545/reductions-in-readmission-rates-are-associated-with-modest-improvements-in-patient-reported-health-gains-following-hip-and-knee-replacement-in-england
#1
Rocco Friebel, Kumar Dharmarajan, Harlan M Krumholz, Adam Steventon
BACKGROUND: Although many hospital readmission reduction initiatives have been introduced globally, health care systems ultimately aim to improve patients' health and well-being. We examined whether the hospitals that report greater success in reducing readmissions also see greater improvements in patient-reported outcomes. RESEARCH DESIGN: We examined hospital groups (Trusts) that provided hip replacement or knee replacement surgery in England between April 2010 and February 2013...
July 24, 2017: Medical Care
https://www.readbyqxmd.com/read/28737530/ultrasound-characteristics-of-clinically-dislocated-but-reducible-hips-with-ddh
#2
Brendan Striano, Emily K Schaeffer, Travis H Matheney, Vidayadhar V Upasani, Charles T Price, Kishore Mulpuri, Wudbhav N Sankar
BACKGROUND: Although ultrasound (US) is frequently used in diagnosis and management of infantile developmental dysplasia of the hip, precise ultrasonographic parameters of what constitutes a dislocation, subluxation etc remain poorly defined. The purpose of this study was (1) to describe the ultrasonographic characteristics of a large cohort of clinically dislocated but reducible hips and (2) to begin to develop ultrasonographic definitions for what constitutes a hip dislocation. METHODS: A retrospective review of prospectively collected data from an international multicenter study group on developmental dysplasia of the hip was conducted on all patients under 6 months of age with hip(s) that were dislocated at rest but reducible based on initial physical examination (ie, Ortolani positive)...
July 21, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28737528/genetic-variants-of-increased-waist-circumference-in-psychosis
#3
Dzana S Hukic, Urban Ösby, Eric Olsson, Agneta Hilding, Claes-Göran Östenson, Harvest F Gu, Ewa Ehrenborg, Gunnar Edman, Martin Schalling, Catharina Lavebratt, Louise Frisén
OBJECTIVE: We examined whether established metabolic risk genetic variants in the population confer a risk for increased waist circumference in patients with schizophrenia spectrum disorders and also an association with schizophrenia spectrum disorders irrespective of waist circumference. PATIENTS AND METHODS: We analyzed the association in (i) a case-case model in which patients with schizophrenia spectrum disorder with increased waist circumference (≥80 cm for women and ≥94 cm for men) (n=534) were compared with patients with normal waist circumference (<80 cm for women; <94 cm for men) (n=124), and in (ii) a case-control model in which schizophrenia spectrum disorder patients with increased waist circumference or irrespective of waist circumference were compared with population-derived controls (n=494) adjusted for age, sex, fasting glucose, smoking, and family history of diabetes...
July 21, 2017: Psychiatric Genetics
https://www.readbyqxmd.com/read/28736588/the-regulation-of-the-practice-of-acupuncture-by-physicians-in-the-united-states
#4
Katerina Lin, Cynthia Tung
Introduction: The landscape of acupuncture regulation has greatly evolved since the National Institutes of Health Consensus Statement in 1997. In recent decades, acupuncture treatment has become increasingly integrated with conventional medical care. Healthcare practitioners often utilize acupuncture as an adjunctive therapy to help alleviate symptoms of many conditions, such as nausea and pain. The popularity of this complementary and alternative modality has elevated the importance and urgency for states to regulate its practice and safety...
June 1, 2017: Medical Acupuncture
https://www.readbyqxmd.com/read/28731932/investing-in-physicians-is-investing-in-patients-enhancing-patient-safety-through-physician-health-and-well-being-research
#5
Elizabeth Brooks, Doris C Gundersen, Michael H Gendel
Keeping medical practitioners healthy is an important consideration for workforce satisfaction and retention, as well as public safety. However, there is limited evidence demonstrating how to best care for this group. The absence of data is related to the lack of available funding in this area of research. Supporting investigations that examine physician health often "fall through the cracks" of traditional funding opportunities, landing somewhere between patient safety and workforce development priorities...
July 20, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28726342/social-workers-perceptions-of-barriers-to-interpersonal-therapy-implementation-for-treating-postpartum-depression-in-a-primary-care-setting-in-israel
#6
Rena Bina, Adi Barak, Barbara Posmontier, Saralee Glasser, Tali Cinamon
Research on evidence-based practice (EBP) implementation in social work often neglects to include evaluation of application barriers. This qualitative study examined social workers' perspectives of provider- and organisational-related barriers to implementing a brief eight-session interpersonal therapy (IPT) intervention, a time-limited EBP that addresses reducing depressive symptoms and improving interpersonal functioning. Implementation took place in a primary care setting in Israel and was aimed at treating women who have postpartum depression (PPD) symptoms...
July 20, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28720452/socioeconomic-predictors-of-human-papillomavirus-vaccination-in-danish-men-a-nationwide-study
#7
Signe Bollerup, Birgitte Baldur-Felskov, Christian Dehlendorff, Susanne K Kjaer
BACKGROUND: The quadrivalent human papillomavirus vaccine was licensed in Denmark in 2006. Unlike women, men are not offered human papillomavirus vaccination free of charge but can have it at their own expense. We investigated human papillomavirus vaccine uptake by men in Denmark and the socioeconomic factors that may predict human papillomavirus vaccination. METHODS: Using the Civil Registration System, we identified all boys and men aged 9-26 years in 2006-2013 and their mothers...
June 2017: Papillomavirus Research
https://www.readbyqxmd.com/read/28714452/predict-moral-distress-using-workplace-stress-stress-of-conscience-mediated-by-coping-using-roy-adaptation-model-a-path-analysis
#8
Muder Alkrisat
BACKGROUND: Moral distress can be predisposed when nurses are exposed to ambiguous moral situations. PURPOSE: Is to test a conceptual model based on Roy adaptation model (RAM) to examine the relationship among workplace stress, conscience stress, and moral distress mediated by coping. DESIGN: A correlational, cross sectional. RESULTS: Data were collected from 199 licensed nurses. The findings indicated that workplace stress was related negatively to coping processes (β = -...
December 1, 2016: Journal of Nursing Measurement
https://www.readbyqxmd.com/read/28713586/formal-thought-disorder-in-people-at-ultra-high-risk-of-psychosis
#9
Arsime Demjaha, Sara Weinstein, Daniel Stahl, Fern Day, Lucia Valmaggia, Grazia Rutigliano, Andrea De Micheli, Paolo Fusar-Poli, Philip McGuire
BACKGROUND: Formal thought disorder is a cardinal feature of psychosis. However, the extent to which formal thought disorder is evident in ultra-high-risk individuals and whether it is linked to the progression to psychosis remains unclear. AIMS: Examine the severity of formal thought disorder in ultra-high-risk participants and its association with future psychosis. METHOD: The Thought and Language Index (TLI) was used to assess 24 ultra-high-risk participants, 16 people with first-episode psychosis and 13 healthy controls...
July 2017: BJPsych Open
https://www.readbyqxmd.com/read/28713585/associations-of-centrally-acting-ace-inhibitors-with-cognitive-decline-and-survival-in-alzheimer-s-disease
#10
Karim Fazal, Gayan Perera, Mizanur Khondoker, Robert Howard, Robert Stewart
BACKGROUND: Cognitive improvement has been reported in patients receiving centrally acting angiotensin-converting enzyme inhibitors (C-ACEIs). AIMS: To compare cognitive decline and survival after diagnosis of Alzheimer's disease between people receiving C-ACEIs, non-centrally acting angiotensin-converting enzyme inhibitors (NC-ACEIs), and neither. METHOD: Routine Mini-Mental State Examination (MMSE) scores were extracted in 5260 patients receiving acetylcholinesterase inhibitors and analysed against C-/NC-ACEI exposure at the time of Alzheimer's disease diagnosis...
July 2017: BJPsych Open
https://www.readbyqxmd.com/read/28705248/prevention-of-feline-leishmaniosis-with-an-imidacloprid-10-flumethrin-4-5-polymer-matrix-collar
#11
Emanuele Brianti, Luigi Falsone, Ettore Napoli, Gabriella Gaglio, Salvatore Giannetto, Maria Grazia Pennisi, Vito Priolo, Maria Stefania Latrofa, Viviana Domenica Tarallo, Fabrizio Solari Basano, Roberto Nazzari, Katrin Deuster, Matthias Pollmeier, Laura Gulotta, Vito Colella, Filipe Dantas-Torres, Gioia Capelli, Domenico Otranto
BACKGROUND: Leishmaniosis caused by Leishmania infantum is one of the most important vector-borne diseases affecting animals and humans worldwide. Dogs are considered main reservoirs of the zoonotic forms, though in the last years the role of cats as reservoirs has been increasingly investigated. Feline leishmaniosis (FeL) occurs in endemic areas and no specific preventive measures have been investigated so far. In this study the efficacy of a 10% imidacloprid/4.5% flumethrin polymer matrix collar, licensed for tick and flea prevention, has been assessed against FeL in a longitudinal study on 204 privately owned cats from the Aeolian islands (Sicily), an area highly endemic for the disease...
July 14, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28704247/comparison-of-registered-and-reported-outcomes-in-randomized-clinical-trials-published-in-anesthesiology-journals
#12
Philip M Jones, Jeffrey T Y Chow, Miguel F Arango, Jason A Fridfinnson, Nan Gai, Kevin Lam, Timothy P Turkstra
BACKGROUND: Randomized clinical trials (RCTs) provide high-quality evidence for clinical decision-making. Trial registration is one of the many tools used to improve the reporting of RCTs by reducing publication bias and selective outcome reporting bias. The purpose of our study is to examine whether RCTs published in the top 6 general anesthesiology journals were adequately registered and whether the reported primary and secondary outcomes corresponded to the originally registered outcomes...
July 10, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28702848/organic-solvent-exposure-and-depressive-symptoms-among-licensed-pesticide-applicators-in-the-agricultural-health-study
#13
Miriam Siegel, Sarah E Starks, Wayne T Sanderson, Freya Kamel, Jane A Hoppin, Fred Gerr
PURPOSE: Although organic solvents are often used in agricultural operations, neurotoxic effects of solvent exposure have not been extensively studied among farmers. The current analysis examined associations between questionnaire-based metrics of organic solvent exposure and depressive symptoms among farmers. METHODS: Results from 692 male Agricultural Health Study participants were analyzed. Solvent type and exposure duration were assessed by questionnaire. An "ever-use" variable and years of use categories were constructed for exposure to gasoline, paint/lacquer thinner, petroleum distillates, and any solvent...
July 12, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28700529/rheumatologists-modestly-more-likely-to-counsel-smokers-in-visits-without-rheumatoid-arthritis-control-an-observational-study
#14
Andrew P Vreede, Heather M Johnson, Megan Piper, Daniel J Panyard, Joanna C Wong, Christie M Bartels
BACKGROUND: Among patients with rheumatoid arthritis (RA), smoking increases risk of severe RA and pulmonary and cardiovascular disease. Despite this, little is known about smoking cessation counseling by rheumatologists. OBJECTIVES: We examined predictors of tobacco counseling in RA patients who smoke including the effect of perceived RA control. We hypothesized that patients with controlled RA would receive more counseling according to the competing demands model, which explains that preventive care gaps occur as a result of competing provider, patient, and clinic factors...
August 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28700406/the-use-of-multistate-models-to-examine-associations-of-stress-and-adherence-with-transitions-among-hiv-care-states-observed-in-a-clinical-hiv-cohort
#15
Sandra Blitz, Tony Antoniou, Ann Burchell, Sharon Walmsley, Lucia Light, Sandra Gardner, Sean Rourke, Curtis Cooper, Claire Kendall, Mona Loutfy, Anita Rachlis, Wendy Wobeser, Anita Benoit, Janet Raboud
BACKGROUND: The "cascade of care" is a framework for quantifying the trajectory of people with HIV along the continuum of HIV care. We extended this framework to recognize that individuals may transition back and forth between states of care and to identify factors associated with movement among states of care over time, with particular focus on stress, depression and adherence. METHODS: The Ontario HIV Treatment Network Cohort Study is a multisite HIV clinical cohort...
July 3, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28700366/sex-differences-in-cannabis-use-disorder-diagnosis-involved-hospitalizations-in-the-united-states
#16
He Zhu, Li-Tzy Wu
OBJECTIVES: The study examined sex differences in trend and clinical characteristics of cannabis use disorder (CUD) diagnosis involved hospitalizations among adult patients. METHODS: We analyzed hospitalization data from the 2007-2011 Nationwide Inpatient Samples for patients aged 18-64 years (N = 15,114,930). Descriptive statistics were used to characterize demographic variables and to compare the proportions of CUD diagnosis and comorbid patterns between male and female hospitalizations...
July 11, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28700265/safety-and-immunogenicity-of-a-quadrivalent-influenza-vaccine-in-adults-65%C3%A2-years-of-age-and-older
#17
David P Greenberg, Corwin A Robertson, H Keipp Talbot, Michael D Decker
Frequent mismatches between the predominant circulating B strain lineage and the B strain lineage in trivalent influenza vaccines have resulted in missed opportunities to prevent influenza illness. Quadrivalent influenza vaccines containing B strains from each of the two lineages have been developed for improved prevention of influenza B infections. Here, we describe the results of a phase III, randomized, double-blind, active-controlled, multicenter trial examining the safety and immunogenicity of a split-virion inactivated quadrivalent influenza vaccine (IIV4) in 675 adults ≥ 65 years of age (NCT01218646)...
July 12, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28696997/number-of-offspring-and-cardiovascular-disease-risk-in-men-and-women-the-role-of-shared-lifestyle-characteristics
#18
Maria C Magnus, Stamatina Iliodromiti, Debbie A Lawlor, Janet M Catov, Scott M Nelson, Abigail Fraser
BACKGROUND: Previous studies of the number of offspring and cardiovascular disease (CVD) report conflicting findings. We re-examined this association in both sexes to clarify the role of the cardiometabolic changes that women experience during pregnancy versus shared lifestyle characteristics. METHODS: We studied 180,626 women and 133,259 men participating in the UK Biobank cohort who were free of CVD at baseline. CVD events were obtained from hospital and death registers...
July 10, 2017: Epidemiology
https://www.readbyqxmd.com/read/28695562/medical-use-of-cannabis-in-switzerland-analysis-of-approved-exceptional-licences
#19
Gablu Kilcher, Marcel Zwahlen, Christopher Ritter, Lukas Fenner, Matthias Egger
AIMS OF THE STUDY: In recent years, the Swiss Federal Office of Public Health (FOPH) granted exceptional licenses for the medical use of cannabinoids, typically for 6 months with possible extensions. A systematic review of cannabinoids for medical use commissioned by the FOPH supports the use of cannabinoids for the treatment of chronic pain and spasticity. However, little is known about the patients treated with cannabinoids. We aimed to study medical uses of cannabinoids as part of the FOPH's programme of exceptional licenses...
July 11, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28694193/mutant-analysis-of-cdt1-s-function-in-suppressing-nascent-strand-elongation-during-dna-replication-in-xenopus-egg-extracts
#20
Yuta Nakazaki, Takashi Tsuyama, Yutaro Azuma, Mikiko Takahashi, Shusuke Tada
The initiation of DNA replication is strictly regulated by multiple mechanisms to ensure precise duplication of chromosomes. In higher eukaryotes, activity of the Cdt1 protein is temporally regulated during the cell cycle, and deregulation of Cdt1 induces DNA re-replication. In previous studies, we showed that excess Cdt1 inhibits DNA replication by suppressing progression of replication forks in Xenopus egg extracts. Here, we investigated the functional regions of Cdt1 that are required for the inhibition of DNA replication...
July 8, 2017: Biochemical and Biophysical Research Communications
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