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https://www.readbyqxmd.com/read/28107257/perceived-stress-as-a-risk-factor-for-dyspepsia-a-register-based-cohort-study
#1
Ulrik Deding, Christian Torp-Pedersen, Henrik Bøggild
OBJECTIVE: Dyspepsia is a common condition and has a huge impact on quality of life and working capacity, but its causes are not well understood. An association between stress and dyspepsia has been debated for decades, but the issue has not been resolved. We examined the 3-year risk of redeeming a proton-pump inhibitor or an H2-receptor antagonist as a proxy of dyspepsia according to the level of perceived stress. PARTICIPANTS AND METHODS: Perceived stress was measured in a general health survey of 16 124 Danes aged older than 16 years of age in 2010 using Cohen's Perceived Stress Scale...
January 19, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28107251/internet-delivered-self-management-support-for-improving-coronary-heart-disease-and-self-management-related-outcomes-a-systematic-review
#2
Jorge Palacios, Geraldine A Lee, Maria Duaso, Abigail Clifton, Ian J Norman, Derek Richards, Elizabeth Alexandra Barley
INTRODUCTION: Coronary heart disease (CHD) is associated with significant morbidity and mortality, including mental health comorbidity, which is associated with poor outcomes. Self-management is key, but there is limited access to self-management support. Internet-delivered interventions may increase access. OBJECTIVE: The aim of this study was to conduct a systematic review to (1) determine the effectiveness of Internet-delivered CHD self-management support for improving CHD, mood, and self-management related outcomes and (2) identify and describe essential components for effectiveness...
January 20, 2017: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28106709/systemic-pharmacokinetics-and-pharmacodynamics-of-intravitreal-aflibercept-bevacizumab-and-ranibizumab
#3
Robert L Avery, Alessandro A Castellarin, Nathan C Steinle, Dilsher S Dhoot, Dante J Pieramici, Robert See, Stephen Couvillion, Maʼan A Nasir, Melvin D Rabena, Mauricio Maia, Sherri Van Everen, Kha Le, William D Hanley
PURPOSE: To evaluate the systemic pharmacokinetics (PKs) of aflibercept, bevacizumab, and ranibizumab in patients with neovascular age-related macular degeneration (AMD), diabetic macular edema (DME), or retinal vein occlusion (RVO). METHODS: Prospective, open-label, nonrandomized clinical trial of patients with AMD, DME, or RVO who were antivascular endothelial growth factor (VEGF) naïve or had not received anti-VEGF for ≥4 months. Patients received 3 monthly intravitreal injections of aflibercept 2...
January 18, 2017: Retina
https://www.readbyqxmd.com/read/28099402/transplant-center-volume-and-the-risk-of-pancreas-allograft-failure
#4
Tarek Alhamad, Andrew F Malone, Daniel C Brennan, Robert J Stratta, Su-Hsin Chang, Jason R Wellen, Timothy A Horwedel, Krista L Lentine
BACKGROUND: Successful pancreas transplantation requires surgical expertise and multidisciplinary medical management. The impact of transplant center volume on pancreas allograft survival remains unclear. METHODS: We examined Organ Procurement and Transplantation Network (OPTN) data on 11,568 simultaneous pancreas-kidney (SPK) and 4308 solitary pancreas (pancreas transplant alone and pancreas after kidney) transplants between 2000 and 2013. RESULTS: Average annual transplant center volume was categorized by tertiles into low, medium and high volume, respectively, as follows: 1-6 (n=3,861), 7-13 (n=3,891), and 14-34 (n=3,888) for SPK, and 1-3 (n=1,417), 4-10 (n=1,518), and 11-33 (n=1,377) for solitary pancreas transplants...
January 17, 2017: Transplantation
https://www.readbyqxmd.com/read/28099286/multicenter-study-validating-accuracy-of-a-continuous-respiratory-rate-measurement-derived-from-pulse-oximetry-a-comparison-with-capnography
#5
Sergio D Bergese, Michael L Mestek, Scott D Kelley, Robert McIntyre, Alberto A Uribe, Rakesh Sethi, James N Watson, Paul S Addison
BACKGROUND: Intermittent measurement of respiratory rate via observation is routine in many patient care settings. This approach has several inherent limitations that diminish the clinical utility of these measurements because it is intermittent, susceptible to human error, and requires clinical resources. As an alternative, a software application that derives continuous respiratory rate measurement from a standard pulse oximeter has been developed. We sought to determine the performance characteristics of this new technology by comparison with clinician-reviewed capnography waveforms in both healthy subjects and hospitalized patients in a low-acuity care setting...
January 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28098483/academic-performance-on-first-year-medical-school-exams-how-well-does-it-predict-later-performance-on-knowledge-based-and-clinical-assessments
#6
Edward Krupat, Stephen R Pelletier, Jules L Dienstag
Number of appearances in the bottom quartile of 1st-year medical school exams were used to represent the extent to which students were having academic difficulties. Medical educators have long expressed a desire to have indicators of medical student performance that have strong predictive validity. Predictors traditionally used fell into 4 general categories: demographic (e.g., gender), other background factors (e.g., college major), performance/aptitude (e.g., medical college admission test scores), and noncognitive factors (e...
January 18, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28095808/associations-between-access-to-alcohol-outlets-and-alcohol-intake-and-depressive-symptoms-in-women-from-socioeconomically-disadvantaged-neighbourhoods-in-australia
#7
Karen E Lamb, Lukar E Thornton, Megan Teychenne, Catherine Milte, Ester Cerin, Kylie Ball
BACKGROUND: This study examined associations between alcohol outlet access and alcohol intake, depressive symptoms score and risk of depression among women residing in disadvantaged neighbourhoods in Victoria, Australia. METHODS: Data on depressive symptoms, alcohol intake and socio-demographic characteristics were obtained from a sample of 995 adult women from Victoria, Australia who were surveyed as part of the Resilience in Eating and Activity Despite Inequality (READI) study...
January 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28095431/hair-measurements-of-cortisol-dhea-and-dhea-to-cortisol-ratio-as-biomarkers-of-chronic-stress-among-people-living-with-hiv-in-china-known-group-validation
#8
Shan Qiao, Xiaoming Li, Samuele Zilioli, Zheng Chen, Huihua Deng, Juxian Pan, Weigui Guo
BACKGROUND: Existing literature suggests that endocrine measures, including the steroid hormones of cortisol and Dehydroepiandrosterone (DHEA), as well as the DHEA to cortisol ratio in the human hair can be used as promising biomarkers of chronic stress among humans. However, data are limited regarding the validity of these measures as biomarkers of chronic stress among people living with HIV (PLWH), whose endocrine system or hypothalamic pituitary adrenal (HPA) axis may be affected by HIV infection and/or antiretroviral therapy (ART) medications...
2017: PloS One
https://www.readbyqxmd.com/read/28095034/self-reported-driving-under-the-influence-of-alcohol-and-cannabis-among-ontario-students-associations-with-graduated-licensing-risk-taking-and-substance-abuse
#9
Steven Cook, Danielle Shank, Tara Bruno, Nigel E Turner, Robert E Mann
OBJECTIVE: This paper describes the patterns of self-reported driving under the influence of alcohol (DUIA) and driving under the influence of cannabis (DUIC) among licenced Ontario students in 2009, and examines their associations with graduated licencing, risk taking, and substance use problems for understanding DUIA and DUIC behaviours. Ontario's graduated licencing system requires new drivers to hold a G1 license for a minimum of 8 months, and a G2 licence for a minimum of 12 months before a full and unrestricted G license can be obtained...
January 17, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28078788/violence-involvement-among-nightlife-patrons-the-relative-role-of-demographics-and-substance-use
#10
Trond Nordfjaern
The nightlife setting is a risk context for violence involvement that ultimately may cause severe injuries and fatalities. Few studies have examined associations between alcohol and illicit substance use with physical violence involvement among nightlife patrons. The aim of the current study was to investigate the relative role of demographics and substance use characteristics for nightlife violence involvement among Norwegian nightlife patrons. A cross-sectional self-completion survey was conducted outside 12 licensed premises in Oslo (n = 1099, response rate = 76%) and each respondent's BAC level was measured by a breathalyzer and registered on the questionnaire...
January 12, 2017: Aggressive Behavior
https://www.readbyqxmd.com/read/28077453/state-regulatory-approaches-for-dementia-care-in-residential-care-and-assisted-living
#11
Paula C Carder
PURPOSE: This policy study analyzed states' residential care and assisted living (RC/AL) regulations for dementia care requirements. Estimates suggest that at least half of RC/AL residents have dementia, and 22% of settings provide or specialize in dementia care. Residents with dementia might benefit from regulations that account for specific behaviors and needs associated with dementia, making states' RC/AL regulations address dementia care an important policy topic. DESIGN AND METHODS: This study examined RC/AL regulations in all 50 states and the District of Columbia for regulatory requirements on five topics important to the quality of life of RC/AL residents with dementia: pre-admission assessment, consumer disclosure, staffing types and levels, administrator training, and physical environment...
January 10, 2017: Gerontologist
https://www.readbyqxmd.com/read/28077126/what-do-we-know-about-the-effects-of-exposure-to-low-alcohol-and-equivalent-product-labelling-on-the-amounts-of-alcohol-food-and-tobacco-people-select-and-consume-a-systematic-review
#12
Ian Shemilt, Vivien Hendry, Theresa M Marteau
BACKGROUND: Explicit labelling of lower strength alcohol products could reduce alcohol consumption by attracting more people to buy and drink such products instead of higher strength ones. Alternatively, it may lead to more consumption due to a 'self-licensing' mechanism. Equivalent labelling of food or tobacco (for example "Low fat" or "Low tar") could influence consumption of those products by similar mechanisms. This systematic review examined the effects of 'Low alcohol' and equivalent labelling of alcohol, food and tobacco products on selection, consumption, and perceptions of products among adults...
January 12, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28077034/written-reflection-in-assessment-and-appraisal-gp-and-gp-trainee-views
#13
Pamela Curtis, Gordon Taylor, Ruth Riley, Tom Pelly, Michael Harris
BACKGROUND: In the UK, evidence of written reflection is part of licensing and revalidation for general practitioners (GPs). However, there is little evidence of specific benefits compared to other forms of reflective practice. AIM: To seek GPs' and general practice (GP) trainees' views on the role of written reflection in learning and assessment. DESIGN AND SETTING: An online survey of 1005 GPs and GP trainees (GPTs) in the UK. METHOD: An anonymous questionnaire containing 38 attitudinal items was administered...
January 12, 2017: Education for Primary Care
https://www.readbyqxmd.com/read/28072594/genetics-consultation-rates-following-a-diagnosis-of-high-grade-serous-ovarian-carcinoma-in-the-canadian-province-of-ontario
#14
Jacob McGee, Karen Panabaker, Sean Leonard, Peter Ainsworth, Laurie Elit, Salimah Z Shariff
OBJECTIVE: In 2001, the province of Ontario expanded cancer genetic testing eligibility to include all women with high-grade serous ovarian carcinoma (HGSC) of the ovary, fallopian tube, and peritoneum. The aim of this study was to determine the proportion of women who attended genetics counseling for consideration of BRCA1/2 gene analysis. We also sought to examine if regional differences in consultation rate exist across administrative health regions in the province of Ontario. METHODS: We identified all women with a pathological diagnosis of HGSC in the province of Ontario between 1997 until 2011...
January 9, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28069887/mandatory-physician-reporting-of-at-risk-drivers-the-older-driver-example
#15
Yll Agimi, Steven M Albert, Ada O Youk, Patricia I Documet, Claudia A Steiner
PURPOSE OF THE STUDY: In a number of states, physicians are mandated by state law to report at-risk drivers to licensing authorities. Often these patients are older adult drivers who may exhibit unsafe driving behaviors, have functional/cognitive impairments, or are diagnosed with conditions such as Alzheimer's disease and/or seizure disorders. The hypothesis that mandatory physician reporting laws reduce the rate of crash-related hospitalizations among older adult drivers was tested...
January 9, 2017: Gerontologist
https://www.readbyqxmd.com/read/28068123/coreference-and-antecedent-representation-across-languages
#16
Sol Lago, Shayne Sloggett, Zoe Schlueter, Wing Yee Chow, Alexander Williams, Ellen Lau, Colin Phillips
Previous studies have shown that speakers of languages such as German, Spanish, and French reactivate the syntactic gender of the antecedent of a pronoun to license gender agreement. As syntactic gender is assumed to be stored in the lexicon, this has motivated the claim that pronouns in these languages reactivate the lexical entry of their antecedent noun. In contrast, in languages without syntactic gender such as English, lexical retrieval might be unnecessary. We used eye-tracking while reading to examine whether antecedent retrieval involves rapid semantic and phonological reactivation...
January 9, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28067757/family-medicine-physicians-with-substance-use-disorder-a-5-year-outcome-study
#17
John S Rose, Michael D Campbell, Peter Yellowlees, Gregory E Skipper, Robert L DuPont
OBJECTIVES: There is little published evidence on how well family medicine physicians (FMPs) with substance use disorder (SUD) perform in Physician Health Programs (PHPs). We examined outcomes for FMP compared with non-FMP physicians. METHODS: This study utilized data from a 5-year, longitudinal, cohort study involving 904 physicians with diagnoses of SUD consecutively admitted to one of 16 state PHPs between 1995 and 2001. We compared 175 FMPs to 687 other physicians...
January 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28067754/moderate-renal-failure-accentuates-t1-signal-enhancement-in-the-deep-cerebellar-nuclei-of-gadodiamide-treated-rats
#18
Marlène Rasschaert, Jean-Marc Idée, Philippe Robert, Nathalie Fretellier, Véronique Vives, Xavier Violas, Sébastien Ballet, Claire Corot
OBJECTIVES: The purpose of this preclinical study was to investigate whether moderate chronic kidney disease is a factor in potentiating gadolinium (Gd) uptake in the brain. MATERIALS AND METHODS: A comparative study was performed on renally impaired (subtotal nephrectomy) rats versus rats with normal renal function. The animals received 4 daily injections of 0.6 mmol Gd/kg a week for 5 weeks (cumulative dose of 12 mmol Gd/kg) of gadodiamide or saline solution. The MR signal enhancement in the deep cerebellar nuclei was monitored by weekly magnetic resonance imaging examinations...
November 28, 2016: Investigative Radiology
https://www.readbyqxmd.com/read/28063848/challenges-with-implementing-a-patient-centered-medical-home-model-for-women-veterans
#19
Emmeline Chuang, Julian Brunner, Selene Mak, Alison B Hamilton, Ismelda Canelo, Jill Darling, Lisa V Rubenstein, Elizabeth M Yano
BACKGROUND: The Veterans Health Administration (VA) Patient Aligned Care Team (PACT) initiative aims to ensure that all patients receive care consistent with medical home principles. Women veterans' unique care needs and minority status within the VA pose challenges to delivery of equitable, comprehensive primary care for this population. Currently, little is known about whether and/or how PACT should be tailored to better meet women veteran needs. METHODS: In 2014, we conducted semistructured interviews with 73 primary care providers and staff to examine facilitators and barriers encountered in providing PACT-principled care to women veterans...
January 4, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28060237/a-comparison-of-matched-and-unmatched-orthopaedic-surgery-residency-applicants-from-2006-to-2014-data-from-the-national-resident-matching-program
#20
John B Schrock, Matthew J Kraeutler, Michael R Dayton, Eric C McCarty
BACKGROUND: The Association of American Medical Colleges publishes residency match data and reports through the National Resident Matching Program (NRMP) every year. The purpose of this study was to analyze trends in orthopaedic surgery residency matching data and characteristics of successful applicants to counsel medical students with regard to their chances of matching. METHODS: The annual reports of the NRMP were searched annually from 2006 to 2014 to determine the number of orthopaedic surgery residency positions available, the number of applicants, and the match rate among applicants...
January 4, 2017: Journal of Bone and Joint Surgery. American Volume
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