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https://www.readbyqxmd.com/read/28209159/do-coursework-summative-assessments-predict-clinical-performance-a-systematic-review
#1
Rebecca Terry, Wayne Hing, Robin Orr, Nikki Milne
BACKGROUND: Two goals of summative assessment in health profession education programs are to ensure the robustness of high stakes decisions such as progression and licensing, and predict future performance. This systematic and critical review aims to investigate the ability of specific modes of summative assessment to predict the clinical performance of health profession education students. METHODS: PubMed, CINAHL, SPORTDiscus, ERIC and EMBASE databases were searched using key terms with articles collected subjected to dedicated inclusion criteria...
February 16, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28195947/alpha-msh-induces-vasodilatation-and-exerts-cardioprotection-via-the-heme-oxygenase-pathway-in-rat-hearts
#2
Miklos Vecsernyes, Miklos Szokol, Mariann Bombicz, Daniel Priksz, Rudolf Gesztelyi, Gabor Aron Fulop, Balazs Varga, Bela Juhasz, David Haines, Arpad Tosaki
Alpha-melanocyte-stimulating hormone (α-MSH) is a protein with known capacity for protection against cardiovascular ischemia-reperfusion (I/R) injury. The present investigation evaluates the capacity of α-MSH to mitigate I/R effects in an isolated working rat heart model and determine the dependency of these alterations on the activity of heme oxygenase-1 (HO-1, hsp-32), a heat shock protein that functions as a major antioxidant defense molecule. Healthy male Sprague-Dawley rats were used for all experiments...
February 13, 2017: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/28195849/detection-and-alterations-of-acetylcarnitine-in-human-skeletal-muscles-by-1h-mrs-at-7-t
#3
Radka Klepochová, Ladislav Valkovič, Martin Gajdošík, Thomas Hochwartner, Harald Tschan, Michael Krebs, Siegfried Trattnig, Martin Krššák
OBJECTIVES: The aims of this study were to detect the acetylcarnitine resonance line at 2.13 ppm in the human vastus lateralis and soleus muscles, assess T1 and T2 relaxation times, and investigate the diurnal and exercise-related changes in absolute concentration noninvasively, using proton magnetic resonance spectroscopy at 7 T. MATERIALS AND METHODS: All measurements were performed on a 7 T whole-body Magnetom MR system with a 28-channel knee coil. Five healthy, moderately trained volunteers participated in the assessment of the detectability, repeatability, and relaxation times of acetylcarnitine...
February 10, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28195026/from-academic-laboratory-to-the-market-disclosed-and-undisclosed-narratives-of-commercialization
#4
Adi Sapir, Amalya L Oliver
This paper examines how the Weizmann Institute of Science has been telling the story of the successful commercialization of a scientific invention, through its corporate communication channels, from the early 1970s to today. The paper aims to shed light on the transformation processes by which intellectual-property-based commercialization activities have become widely institutionalized in universities all over the world, and on the complexities, ambiguities and tensions surrounding this transition. We look at the story of the scientific invention of Copolymer-1 at the Weizmann Institute of Science and its licensing to Teva Pharmaceutical Industries, which subsequently developed the highly successful drug Copaxone for the treatment of multiple sclerosis...
February 2017: Social Studies of Science
https://www.readbyqxmd.com/read/28192872/premedical-anatomy-experience-and-student-performance-in-medical-gross-anatomy
#5
Peter Kondrashov, Dalton J McDaniel, Rebecca M Jordan
INTRODUCTION: Gross anatomy is considered one of the most important basic science courses in medical education, yet few medical schools require its completion prior to matriculation. The effect of taking anatomy courses before entering medical school on performance in medical gross anatomy has been previously studied with inconsistent results. MATERIALS AND METHODS: The effect of premedical anatomy coursework on performance in medical gross anatomy, overall medical school grade point average (GPA), and Comprehensive Osteopathic Medical Licensing Examination Level 1 (COMLEX 1) score was evaluated in 456 first-year osteopathic medical students along with a survey on its perceived benefits on success in medical gross anatomy course...
February 13, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28192101/transforming-gastroenterology-care-with-telemedicine
#6
REVIEW
Corey A Siegel
Healthcare is changing rapidly, so we must change with the times to develop more efficient, practical, cost-effective and, importantly, high-quality methods to care for patients. We teach medial students that optimal patient care requires face to face interactions, to collect information on patients' history, and the physical examination. However, management of many patients-especially those with chronic diseases-does not always require physical examination. Telemedicine offers an opportunity to take advantage of technology while leveraging the progressive push towards efficiency and value, but also requires the belief that excellent patient care is not always provided in person...
February 9, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28188433/the-clinical-effectiveness-of-ranibizumab-treat-and-extend-regimen-in-namd-systematic-review-and-network-meta-analysis
#7
REVIEW
Andriy Danyliv, Julie Glanville, Rachael McCool, Alberto Ferreira, Adrian Skelly, Ruth Pulikottil Jacob
INTRODUCTION: Neovascular age-related macular degeneration (nAMD) is a chronic eye condition that causes severe deterioration of vision and ultimately blindness. Two vascular endothelial growth factor inhibitors are approved for nAMD treatment in Europe: ranibizumab and aflibercept. The European license for ranibizumab was updated with an individualized "treat and extend" (T&E) regimen, which involves more proactive treatment based on changes in best corrected visual acuity (BCVA) and/or anatomical outcomes...
February 10, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28186618/study-of-individualization-and-bias-in-nursing-home-fall-prevention-practices
#8
Cathleen S Colón-Emeric, Kirsten Corazzini, Eleanor McConnell, Wei Pan, Mark Toles, Rasheeda Hall, Melissa Batchelor-Murphy, Tracey L Yap, Amber L Anderson, Andrew Burd, Ruth A Anderson
OBJECTIVES: Little is known about how nursing home staff use resident characteristics to individualize care delivery or whether care is affected by implicit bias. DESIGN: Randomized factorial clinical vignette survey. SETTING: Sixteen nursing homes in North Carolina. PARTICIPANTS: Nursing, rehabilitation, and social services staff (n = 433). MEASUREMENTS: Vignettes describing hypothetical residents were generated from a matrix of clinical and demographic characteristics...
February 10, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28174460/inter-and-intra-rater-agreement-of-static-posture-analysis-using-a-mobile-application
#9
David M Boland, Eric V Neufeld, Jack Ruddell, Brett A Dolezal, Christopher B Cooper
[Purpose] To determine the intra- and inter-rater agreement of a mobile application, PostureScreen Mobile(®) (PSM), that assesses static standing posture. [Subjects and Methods] Three examiners with different levels of experience of assessing posture, one licensed physical therapist and two untrained undergraduate students, performed repeated postural assessments of 10 subjects, fully clothed or minimally clothed, using PSM on two nonconsecutive days. Anterior and right lateral images were captured and seventeen landmarks were identified on them...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28173725/contrast-enhanced-ultrasound-using-sulfur-hexafluoride-is-safe-in-the-pediatric-setting
#10
Alvaro Torres, Seppo K Koskinen, Henrik Gjertsen, Björn Fischler
Background Contrast-enhanced ultrasound (CEUS) by using sulfur hexafluoride microbubbles is not licensed for use in children, but its off-label use is widespread. Purpose To outline our experience with the off-label use of CEUS in children, specifically with regards to safety. Material and Methods We retrieved all records of 10681 patients aged under 18 years who underwent abdominal ultrasound (US) January 2004 to December 2014. We then identified those who underwent an abdominal CEUS using sulfur hexafluoride microbubbles...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28169572/relation-of-adolescents-physical-activity-to-after-school-recreation-environment
#11
Christina M Thornton, Kelli L Cain, Terry L Conway, Jacqueline Kerr, Brian E Saelens, Lawrence D Frank, Karen Glanz, James F Sallis
BACKGROUND: The after-school period provides an opportune context for adolescent physical activity. This study examined how characteristics of after-school recreation environments related to adolescent physical activity. METHODS: Participants were 889 adolescents aged 12-17 (M = 14.1, SD = 1.4) from two US regions. Adolescents reported on whether their school offered after-school supervised physical activity, access to play areas/fields, and presence of sports facilities...
February 7, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28167421/self-reported-vs-state-recorded-motor-vehicle-collisions-among-older-community-dwelling-individuals
#12
B A Singletary, A N Do, J P Donnelly, C Huisingh, M T Mefford, R Modi, F L Mondesir, Y Ye, C Owsley, G McGwin
INTRODUCTION: Motor vehicle collisions (MVCs) continue to place an increased burden on both individuals and health care systems. Self-reported and state-recorded police reports are the most common methods for MVC evaluation in epidemiologic studies, with varying degrees of agreement of information when compared in previous studies. The objective of the current study is to address the differences in MVC reporting and provide a more robust measure of the agreement between self-reported and state-recorded MVCs in a community dwelling population of older adults...
February 3, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28166872/investigating-the-impact-of-static-roadside-advertising-on-drivers-situation-awareness
#13
Kristie L Young, Amanda N Stephens, David B Logan, Michael G Lenné
Roadside advertising has the potential to create a crash risk for drivers as it may distract attention from driving at critical times. In an on-road instrumented vehicle study, we examined if and how static advertising billboards affect drivers' situation awareness across different driving environments. Nineteen fully licensed drivers drove an instrumented vehicle around a 38 km urban test route comprising freeway, busy urban retail and arterial road sections. The route contained a number of static billboards...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28166175/using-twitter-to-identify-and-respond-to-food-poisoning-the-food-safety-stl-project
#14
Jenine K Harris, Jared B Hawkins, Leila Nguyen, Elaine O Nsoesie, Gaurav Tuli, Raed Mansour, John S Brownstein
CONTEXT: Foodborne illness affects 1 in 4 US residents each year. Few of those sickened seek medical care or report the illness to public health authorities, complicating prevention efforts. Citizens who report illness identify food establishments with more serious and critical violations than found by regular inspections. New media sources, including online restaurant reviews and social media postings, have the potential to improve reporting. OBJECTIVE: We implemented a Web-based Dashboard (HealthMap Foodborne Dashboard) to identify and respond to tweets about food poisoning from St Louis City residents...
February 3, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28166142/detection-and-viability-of-colorectal-liver-metastases-after-neoadjuvant-chemotherapy-a-multiparametric-pet-ct-mri-study
#15
Vincent Dunet, Nermin Halkic, John O Prior, Anass Anaye, Reto A Meuli, Christine Sempoux, Alban Denys, Sabine Schmidt
PURPOSE: The aim of this study was to compare combined gadolinium-ethoxybenzyl-diethylenetriamine-pentaacetic acid (Gd-EOB-DTPA)-enhanced and diffusion-weighted (DW) MRI with IV contrast-enhanced F-FDG PET/CT to detect and assess the viability of colorectal liver metastases (CLMs) after neoadjuvant chemotherapy (NAC). PATIENTS AND METHODS: After NAC, 45 patients with CLMs were prospectively enrolled and underwent combined Gd-EOB-DTPA-enhanced and DW-MRI and contrast-enhanced F-FDG PET/CT...
February 3, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28157766/effect-of-interaction-between-noise-and-a1166c-site-of-at1r-gene-polymorphism-on-essential-hypertension-in-an-iron-and-steel-enterprise-workers
#16
Junwang Tong, Ying Wang, Juxiang Yuan, Jingbo Yang, Zhaoyang Wang, Yao Zheng, Feng Chai, Xiangwen Li
OBJECTIVE: This study aimed to analyze the interaction of Angiotensin II type 1 receptor (AT1R) gene polymorphism and occupational noise on the occurrence of essential hypertension (EH) in steel and iron enterprise men workers. METHODS: A case control study of 935 iron and steel enterprise men workers was conducted, which included 312 cases of hypertension and 623 cases without hypertension. The noise at the workplace was assessed. Polymorphism of AT1R of the workers was examined using polymerase chain reaction - restriction fragment length polymorphism...
February 2, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28151838/retinal-blood-flow-after-intravitreal-bevacizumab-is-a-predictive-factor-for-outcomes-of-macular-edema-associated-with-central-retinal-vein-occlusion
#17
Makiko Matsumoto, Kiyoshi Suzuma, Yoshihisa Yamada, Eiko Tsuiki, Azusa Fujikawa, Takashi Kitaoka
PURPOSE: To investigate whether retinal blood flow levels after intravitreal bevacizumab (IVB) treatment are correlated with the outcomes of patients with macular edema secondary to central retinal vein occlusion. METHODS: This retrospective observational case study enrolled 44 cases nonischemic central retinal vein occlusion. In each patient, visual acuity, central retinal thickness, and mean blur rate, which was measured by laser speckle flowgraphy and represents retinal blood flow velocity, were examined...
February 1, 2017: Retina
https://www.readbyqxmd.com/read/28146041/outcome-based-and-participation-based-wellness-incentives-impacts-on-program-participation-and-achievement-of-health-improvement-targets
#18
Nathan A Barleen, Mary L Marzec, Nicholas L Boerger, Daniel P Moloney, Eric M Zimmerman, Jeff Dobro
OBJECTIVE: This study examined whether worksite wellness program participation or achievement of health improvement targets differed according to four incentive types (participation-based, hybrid, outcome-based, and no incentive). METHODS: The study included individuals who completed biometric health screenings in both 2013 and 2014 and had elevated metrics in 2013 (baseline year). Multivariate logistic regression modeling tested for differences in odds of participation and achievement of health improvement targets between incentive groups; controlling for demographics, employer characteristics, incentive amounts, and other factors...
January 31, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28146035/community-clinicians-and-the-veterans-choice-program-for-ptsd-care-understanding-provider-interest-during-early-implementation
#19
Erin P Finley, Polly H Noël, Michael Mader, Elizabeth Haro, Nancy Bernardy, Craig S Rosen, Mary Bollinger, Hector Garcia, Kathleen Sherrieb, Mary Jo V Pugh
BACKGROUND: In 2014, the Department of Veterans Affairs (VA) implemented the Veterans Choice Program (VCP) to provide reimbursement for community-based care to eligible veterans. Inadequate networks of participating providers may impact the utility of VCP for veterans with posttraumatic stress disorder (PTSD), a complex condition occurring at lower frequency among civilians. OBJECTIVES: To compare characteristics and attitudes of community-based primary care and mental health providers reporting interest or no interest in VCP participation during early implementation; and to examine perceptions and experiences of VCP among "early adopters...
January 31, 2017: Medical Care
https://www.readbyqxmd.com/read/28145975/repeatability-and-longitudinal-assessment-of-foveal-cone-structure-in-cngb3-associated-achromatopsia
#20
Christopher S Langlo, Laura R Erker, Maria Parker, Emily J Patterson, Brian P Higgins, Phyllis Summerfelt, Moataz M Razeen, Frederick T Collison, Gerald A Fishman, Christine N Kay, Jing Zhang, Richard G Weleber, Paul Yang, Mark E Pennesi, Byron L Lam, Jeffrey D Chulay, Alfredo Dubra, William W Hauswirth, David J Wilson, Joseph Carroll
PURPOSE: Congenital achromatopsia is an autosomal recessive disease causing substantial reduction or complete absence of cone function. Although believed to be a relatively stationary disorder, questions remain regarding the stability of cone structure over time. In this study, the authors sought to assess the repeatability of and examine longitudinal changes in measurements of central cone structure in patients with achromatopsia. METHODS: Forty-one subjects with CNGB3-associated achromatopsia were imaged over a period of between 6 and 26 months using optical coherence tomography and adaptive optics scanning light ophthalmoscopy...
January 31, 2017: Retina
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