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https://www.readbyqxmd.com/read/27914766/histomorphological-changes-in-endometriosis-in-a-patient-treated-with-ulipristal-a-case-report
#1
J Bateman, O Bougie, S Singh, S Islam
BACKGROUND: Selective progesterone receptor modulators have shown efficacy in the treatment of endometriosis, however they are not currently licensed in Canada for this purpose. Their histomorphological effects have been well documented in the endometrium, but not in endometriosis. CASE REPORT: The patient presented with uterine fibroids and heavy menstrual bleeding, and was treated with ulipristal acetate over three 90-day courses. She eventually elected to undergo definitive surgical management...
October 25, 2016: Pathology, Research and Practice
https://www.readbyqxmd.com/read/27914116/so-it-is-so-it-shall-be-group-regularities-license-children-s-prescriptive-judgments
#2
Steven O Roberts, Susan A Gelman, Arnold K Ho
When do descriptive regularities (what characteristics individuals have) become prescriptive norms (what characteristics individuals should have)? We examined children's (4-13 years) and adults' use of group regularities to make prescriptive judgments, employing novel groups (Hibbles and Glerks) that engaged in morally neutral behaviors (e.g., eating different kinds of berries). Participants were introduced to conforming or non-conforming individuals (e.g., a Hibble who ate berries more typical of a Glerk)...
December 3, 2016: Cognitive Science
https://www.readbyqxmd.com/read/27913910/a-randomized-trial-of-displaying-paid-price-information-on-imaging-study-and-procedure-ordering-rates
#3
Alyna T Chien, Lisa Soleymani Lehmann, Laura A Hatfield, Kate E Koplan, Carter R Petty, Anna D Sinaiko, Meredith B Rosenthal, Thomas D Sequist
BACKGROUND: Prior studies have demonstrated how price transparency lowers the test-ordering rates of trainees in hospitals, and physician-targeted price transparency efforts have been viewed as a promising cost-controlling strategy. OBJECTIVE: To examine the effect of displaying paid-price information on test-ordering rates for common imaging studies and procedures within an accountable care organization (ACO). DESIGN: Block randomized controlled trial for 1 year...
December 2, 2016: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/27908638/using-the-acmge-milestones-as-a-handover-tool-from-medical-school-to-surgery-residency
#4
Lauren M Wancata, Helen Morgan, Gurjit Sandhu, Sally Santen, David T Hughes
OBJECTIVE: To map current medical school assessments for graduating students to the Accreditation Council for Graduate Medical Education (ACGME) milestones in general surgery, and to pass forward individual performance metrics on level 1 milestones to receiving residency programs. DESIGN: The study included 20 senior medical students who were accepted into surgery internship positions. Data from medical school performance assessments from the third-year surgery clerkship, fourth-year surgery rotations, fourth-year surgery boot camp, Clinical Competency Assessment Examination, and United States Medical Licensing Examination (USMLE) Step 1 and 2 examinations were used to map each student's competency assessments to the General Surgery Milestones based on a scoring system created and validated by independent assessors...
November 28, 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27907983/north-korean-refugee-doctors-preliminary-examination-scores
#5
Sung Uk Chae, Jeong Hee Yang, Joon Seop Hyun, June Hee Kim, Seok Hoon Kang
PURPOSE: Although there have been studies emphasizing the re-education of North Korean (NK) doctors for post-unification of the Korean Peninsula, study on the content and scope of such re-education has yet to be conducted. Researchers intended to set the content and scope of re-education by a comparative analysis for the scores of the preliminary examination, which is comparable to the Korean Medical Licensing Examination (KMLE). METHODS: The scores of the first and second preliminary exams were analyzed by subject using the Wilcoxon signed rank test...
December 2016: Korean Journal of Medical Education
https://www.readbyqxmd.com/read/27907190/are-exam-questions-known-in-advance-using-local-dependence-to-detect-cheating
#6
Stefan Zimmermann, Dietrich Klusmann, Wolfgang Hampe
Cheating is a common phenomenon in high stakes admission, licensing and university exams and threatens their validity. To detect if some exam questions had been affected by cheating, we simulated how data would look like if some test takers possessed item preknowledge: Responses to a small number of items were set to correct for 1-10% of test takers. Item difficulty, item discrimination, item fit, and local dependence were computed using an IRT 2PL model. Then changes in these item properties from the non-compromised to the compromised dataset were scrutinized for their sensitivity to item preknowledge...
2016: PloS One
https://www.readbyqxmd.com/read/27903297/variability-of-staffing-and-staff-mix-across-acute-care-units-in-alberta-canada
#7
Krishna Sharma, Stephanie E Hastings, Esther Suter, Judy Bloom
BACKGROUND: The health workforce has a crucial position in healthcare, and effective distribution of the workforce is one of the critical areas for healthcare improvement. This requires a proper understanding of the allocation of healthcare providers including staffing levels and staffing variability within a healthcare system. High variability may imply significant differences in outcomes and greater opportunity to better distribute staffing and improve patient outcomes. The objective of this study was to examine staffing variation across acute care units in a large and integrated healthcare system...
December 1, 2016: Human Resources for Health
https://www.readbyqxmd.com/read/27903144/parent-burden-in-accessing-outpatient-psychiatric-services-for-adolescent-depression-in-a-large-state-system
#8
Kaitlin P Gallo, S Serene Olin, Amy Storfer-Isser, Briannon C O'Connor, Emma D Whitmyre, Kimberly E Hoagwood, Sarah McCue Horwitz
OBJECTIVE: This study examined barriers facing parents who seek outpatient psychiatric care in a large state system for adolescents with depression. METHODS: A total of 264 outpatient facilities licensed to treat youths in New York were contacted by using a mystery shopper methodology. Callers tracked the number of call attempts, in-person appointments, and other steps required prior to seeing a psychiatrist. RESULTS: Fewer than two-thirds of parents made a psychiatry, therapy, or intake appointment...
December 1, 2016: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/27902759/seroprevalence-and-associated-factors-of-9-valent-human-papillomavirus-hpv-types-among-men-in-the-multinational-him-study
#9
Shams Rahman, Christine M Pierce Campbell, Dana E Rollison, Wei Wang, Tim Waterboer, Angelika Michel, Michael Pawlita, Luisa L Villa, Eduardo Lazcano Ponce, Amy R Borenstein, Anna R Giuliano
BACKGROUND: Human papillomavirus (HPV) is one of the most common sexually transmitted infections worldwide. Recently a 9-valent HPV (9vHPV) prophylactic vaccine was licensed. Seroprevalence prior to vaccine dissemination is needed for monitoring vaccine effectiveness over time. Few studies have assessed the seroprevalence of 9vHPV types in men. OBJECTIVES: To investigate the seroprevalence of 9vHPV vaccine types and associated risk factors among men residing in Brazil, Mexico, and the United States...
2016: PloS One
https://www.readbyqxmd.com/read/27902637/bilateral-congenital-torticollis-a-case-report-with-25-years-of-follow-up
#10
Lukasz Matuszewski, Damian Pietrzyk, Grzegorz Kandzierski, Michal Wilczynski
Unilateral congenital sternocleidomastoid muscle (SCM) contracture causing torticollis is well known. Although the unilateral muscular torticollis is quite often recognized, a bilateral contracture of SCM muscle is very rare. A review of the literature showed only three cases of bilateral congenital torticollis reported over the last two decades. We present a case report of a boy with congenital bilateral torticollis with 25 years of follow-up. Bilateral tenotomies of the right SCM were performed and the child was immobilized in Schanz's cervical orthosis...
November 29, 2016: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/27902529/perceived-exertion-during-exercise-is-associated-with-children-s-energy-intake
#11
S Nicole Fearnbach, Travis D Masterson, Haley A Schlechter, Eric Loken, Danielle S Downs, David Thivel, Kathleen L Keller
PURPOSE: To examine the individual-level factors that predict energy intake (EI) following imposed exercise (EX) and sedentary time (SED) in children. METHODS: Healthy-weight children ages 9-12 years (n = 20) reported to the laboratory for 1 baseline and 2 experimental visits (EX and SED) each separated by 1 week in a randomized crossover design. Percent body fat, weight (kg), and height (m) were used to calculate fat-mass index (FM index) and fat-free mass index (FFM index; kg/m)...
November 29, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27899831/evidence-of-criterion-validity-for-one-pharmacy-school-s-progress-examination-program
#12
Greg L Alston, Wes R Haltom
Objective. To provide evidence that the progress examination program accurately assesses student failure to demonstrate competence. Methods. A progress examination program aligned with each grade level was locally developed and administered annually to 289 PharmD students in the spring of their first year - fourth year. Correlations and linear regressions were performed to compare the examination scores to performance on national licensing examinations and cumulative didactic grade point average (GPA). Odds ratio analysis was run to determine the ability of the passing scores of the progress examination to identify students at increased risk of failing to graduate on time, earn a GPA below 3...
October 25, 2016: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/27898668/the-long-term-safety-public-health-impact-and-cost-effectiveness-of-routine-vaccination-with-a-recombinant-live-attenuated-dengue-vaccine-dengvaxia-a-model-comparison-study
#13
Stefan Flasche, Mark Jit, Isabel Rodríguez-Barraquer, Laurent Coudeville, Mario Recker, Katia Koelle, George Milne, Thomas J Hladish, T Alex Perkins, Derek A T Cummings, Ilaria Dorigatti, Daniel J Laydon, Guido España, Joel Kelso, Ira Longini, Jose Lourenco, Carl A B Pearson, Robert C Reiner, Luis Mier-Y-Terán-Romero, Kirsten Vannice, Neil Ferguson
BACKGROUND: Large Phase III trials across Asia and Latin America have recently demonstrated the efficacy of a recombinant, live-attenuated dengue vaccine (Dengvaxia) over the first 25 mo following vaccination. Subsequent data collected in the longer-term follow-up phase, however, have raised concerns about a potential increase in hospitalization risk of subsequent dengue infections, in particular among young, dengue-naïve vaccinees. We here report predictions from eight independent modelling groups on the long-term safety, public health impact, and cost-effectiveness of routine vaccination with Dengvaxia in a range of transmission settings, as characterised by seroprevalence levels among 9-y-olds (SP9)...
November 2016: PLoS Medicine
https://www.readbyqxmd.com/read/27894343/post-marketing-withdrawal-of-anti-obesity-medicinal-products-because-of-adverse-drug-reactions-a-systematic-review
#14
Igho J Onakpoya, Carl J Heneghan, Jeffrey K Aronson
BACKGROUND: We identified anti-obesity medications withdrawn since 1950 because of adverse drug reactions after regulatory approval, and examined the evidence used to support such withdrawals, investigated the mechanisms of the adverse reactions, and explored the trends over time. METHODS: We conducted searches in PubMed, the World Health Organization database of drugs, the websites of drug regulatory authorities, and selected full texts, and we hand searched references in retrieved documents...
November 29, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27890766/united-states-medical-licensing-exam-step-1-scores-directly-correlate-with-american-board-of-neurological-surgery-scores-a-single-institution-experience
#15
Daniel T Nagasawa, Joel S Beckett, Carlito Lagman, Lawrance K Chung, Benjamin Schmidt, Michael Safaee, Marvin Bergsneider, Neil Martin, Bilwaj Gaonkar, Luke Macyszyn, Isaac Yang
BACKGROUND: Neurosurgery residency is becoming an increasingly competitive match. The process of screening and ultimately ranking applicants is a multifactorial process that lacks uniformity across residency programs. A significant factor that is evaluated is the applicant's performance on the United States Licensing Examination (USMLE) Step 1. USMLE Step 1 scores are often used to project future success in residency and performance on specialty boards like the American Board of Neurological Surgery (ABNS) exam...
November 24, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27882593/can-colleagues-patients-and-supervisors-assessments-predict-successful-completion-of-postgraduate-medical-training
#16
Sathya Naidoo, Safiatu Lopes, Fiona Patterson, Helen M Mead, Sheona MacLeod
BACKGROUND: Workplace-based assessments (WPBAs) are widely used in postgraduate training programmes internationally. WPBAs can function as both an assessment and an educational tool. Although some WPBAs are a mandatory requirement of approved curricula (as in the UK), little previous research has explored the extent to which such assessments are associated with adverse outcomes in postgraduate training. The present study examines whether the assessment element of Multisource Feedback, Patient Satisfaction Questionnaire and Educational Supervisors Review ratings can indicate if a trainee is likely to experience difficulty in successfully completing their planned training programme (i...
November 23, 2016: Medical Education
https://www.readbyqxmd.com/read/27879175/identifying-talented-track-and-field-athletes-the-impact-of-relative-age-effect-on-selection-to-the-spanish-national-athletics-federation-training-camps
#17
Javier Brazo-Sayavera, María Asunción Martínez-Valencia, Lisa Müller, Georgios Andronikos, Russell J J Martindale
This study examined the impact of relative age effect (RAE) on selection to the Spanish National Athletics Federation (RFEA) training camps (TC) between 2006 and 2013. Overall, 1,334 selected athletes at U15 years (cadet) and U17 years (juvenile) were compared against 27,711 licensed but unselected athletes for the same age groups. The results highlighted the influential role of the RAE on selection to national level track and field training camp opportunities. Interestingly, this effect was mediated by age and gender, where effects were stronger for both males and younger athletes (U15), with no evidence of RAE for older (U17) female athletes...
November 23, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27875377/spinal-cord-stimulation-for-refractory-angina-pectoris-a-systematic-review-and-meta-analysis
#18
Xiaoxiao Pan, Hongguang Bao, Yanna Si, Chenjie Xu, Hao Chen, Xianzhong Gao, Xinyi Xie, Yajie Xu, Fan Sun, Lingqing Zeng
OBJECTIVES: Parasthesia free stimulation, such as high frequency and burst have been demonstrated as effective therapies for neuropathic pain. The aim of this meta-analysis was to evaluate the efficacy and safety of conventional spinal cord stimulation (SCS) in the treatment of refractory angina pectoris (RAP). METHODS: Relevant randomized controlled trial (RCT) studies that investigated SCS for patients with RAP were comprehensively searched in Medline, Pubmed, Embase, and Cochrane Library...
November 21, 2016: Clinical Journal of Pain
https://www.readbyqxmd.com/read/27873217/a-retrospective-evaluation-of-the-use-of-mass-spectrometry-in-fda-biologics-license-applications
#19
Sarah Rogstad, Anneliese Faustino, Ashley Ruth, David Keire, Michael Boyne, Jun Park
The characterization sections of biologics license applications (BLAs) approved by the United States Food and Drug Administration (FDA) between 2000 and 2015 were investigated to examine the extent of the use of mass spectrometry. Mass spectrometry was found to be integral to the characterization of these biotherapeutics. Of the 80 electronically submitted monoclonal antibody and protein biotherapeutic BLAs included in this study, 79 were found to use mass spectrometric workflows for protein or impurity characterization...
November 21, 2016: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/27865138/young-driver-risky-behaviour-and-predictors-of-crash-risk-in-australia-new-zealand-and-colombia-same-but-different
#20
Bridie Scott-Parker, Oscar Oviedo-Trespalacios
Young drivers remain overrepresented in road crashes around the world, with road injury the leading cause of death among adolescents. In addition, the majority of road traffic crashes, fatalities and injuries occur in low- and middle-income countries. All young drivers are at risk due to a breadth of age- and inexperience-related factors; however it is well recognised that young drivers may also intentionally engage in risky driving behaviours which increase their crash risk. The aim of this paper is to examine the self-reported risky driving behaviour of young drivers in Australia, New Zealand (high-income countries), and Colombia (middle-income country), and to explore the utility of a crash risk assessment model in these three countries...
November 16, 2016: Accident; Analysis and Prevention
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