keyword
MENU ▼
Read by QxMD icon Read
search

Carlos

keyword
https://www.readbyqxmd.com/read/28109174/%C3%AE-%C3%AE-nac-cooperates-with-sam37-to-mediate-early-stages-of-mitochondrial-protein-import
#1
J Carlos Ponce-Rojas, M Clara Avendaño-Monsalve, A Roberto Yañez-Falcón, Fabiola Jaimes-Miranda, Erika Garay, Francisco Torres-Quiroz, Alexander DeLuna, Soledad Funes
The mitochondrial proteome is mostly composed of nuclear-encoded proteins. Such polypeptides are synthesized with signals that guide their intracellular transport to the surface of the organelle and later within the different mitochondrial sub-compartments until they reach their functional destination. It has been suggested that NAC - a cytosolic chaperone which recognizes nascent chains on translationally active ribosomes - has a role in the import of nuclear-encoded mitochondrial proteins. However, the molecular mechanisms that regulate the NAC-mediated co-translational import are still not clear...
January 21, 2017: FEBS Journal
https://www.readbyqxmd.com/read/28109054/intracoronary-optical-coherence-tomography-clinical-and-research-applications-and-intravascular-imaging-software-overview
#2
Erhan Tenekecioglu, Felipe N Albuquerque, Yohei Sotomi, Yaping Zeng, Pannipa Suwannasom, Hiroki Tateishi, Rafael Cavalcante, Yuki Ishibashi, Shimpei Nakatani, Mohammad Abdelghani, Jouke Dijkstra, Christos Bourantas, Carlos Collet, Antonios Karanasos, Maria Radu, Ancong Wang, Takashi Muramatsu, Ulf Landmesser, Takayuki Okamura, Evelyn Regar, Lorenz Räber, Giulio Guagliumi, Robert T Pyo, Yoshinobu Onuma, Patrick W Serruys
By providing valuable information about the coronary artery wall and lumen, intravascular imaging may aid in optimizing interventional procedure results and thereby could improve clinical outcomes following percutaneous coronary intervention (PCI). Intravascular optical coherence tomography (OCT) is a light-based technology with a tissue penetration of approximately 1 to 3 mm and provides near histological resolution. It has emerged as a technological breakthrough in intravascular imaging with multiple clinical and research applications...
January 21, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28109043/angiographic-assessment-of-aortic-regurgitation-by-video-densitometry-in-the-setting-of-tavi-echocardiographic-and-clinical-correlates
#3
Mohammad Abdelghani, Hiroki Tateishi, Yosuke Miyazaki, Rafael Cavalcante, Osama I I Soliman, Jan G Tijssen, Robbert J de Winter, Jan Baan, Yoshinobu Onuma, Carlos M Campos, Rogério S Leite, José A Mangione, Alexandre Abizaid, Pedro A Lemos, Fabio S de Brito, Patrick W Serruys
OBJECTIVES: We sought to investigate a new angiographic method for aortic regurgitation (AR) severity assessment in the setting of transcatheter aortic valve implantation (TAVI). BACKGROUND: AR after TAVI is common but challenging to quantitate, especially in the cath-lab. METHODS: In 228 patients, AR was quantitated before and after TAVI by echocardiography and by video-densitometric analysis of aortograms. Contrast time-density curves for the aortic root (the reference region) and the left ventricular outflow tract, LVOT were generated...
January 21, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28109003/eradication-of-hcv-and-non-liver-related-non-aids-related-events-in-hiv-hcv-coinfection
#4
Juan Berenguer, Elena Rodríguez-Castellano, Ana Carrero, Miguel A Von Wichmann, Marta Montero, María J Galindo, Josep Mallolas, Manuel Crespo, María J Téllez, Carmen Quereda, José Sanz, Carlos Barros, Cristina Tural, Ignacio Santos, Federico Pulido, Josep M Guardiola, Rafael Rubio, Enrique Ortega, María L Montes, Juan J Jusdado, Gabriel Gaspar, Herminia Esteban, José M Bellón, Juan González-García
: We assessed non-liver-related non-AIDS-related (NLR-NAR) events and mortality in a cohort of HIV/HCV-coinfected patients treated with interferon and ribavirin between 2000 and 2008. The censoring date was May 31, 2014. Cox regression analysis was performed to assess the adjusted hazard rate (HR) of overall death in responders and non-responders. Fine and Gray regression analysis was conducted to determine the adjusted sub-hazard rate (sHR) of NLR deaths and NLR-NAR events considering death as the competing risk...
January 21, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28108961/effects-of-negatively-and-positively-charged-ti-metal-surfaces-on-ceramic-coating-adhesion-and-cell-response
#5
Rodney Marcelo do Nascimento, Vanessa Rafaela de Carvalho, José Silvio Govone, Antônio Carlos Hernandes, Nilson Cristino da Cruz
This manuscript reports an evaluation of the effects of simple chemical-heat treatments on the deposition of different ceramic coatings, i.e., TiO2, CaTiO3 and CaP, on commercially pure titanium (cp-Ti) and Ti6Al4V and the influence of the coatings on cells interaction with the surfaces. The ceramic materials were prepared by the sol-gel method and the coating adhesion was analyzed by pull-off bending tests. The wettability of positively or negatively charged surfaces was characterized by contact angle measurements, which also enabled the calculation of the surface free energy through the polar-apolar liquids approach...
February 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28108886/phase-behaviour-in-complementary-dna-coated-gold-nanoparticles-and-fd-viruses-mixtures-a-numerical-study
#6
Massimiliano Chiappini, Erika Eiser, Francesco Sciortino
A new gel-forming colloidal system based on a binary mixture of fd-viruses and gold nanoparticles functionalized with complementary DNA single strands has been recently introduced. Upon quenching below the DNA melt temperature, such a system results in a highly porous gel state, that may be developed in a new functional material of tunable porosity. In order to shed light on the gelation mechanism, we introduce a model closely mimicking the experimental one and we explore via Monte Carlo simulations its equilibrium phase diagram...
January 2017: European Physical Journal. E, Soft Matter
https://www.readbyqxmd.com/read/28108819/preemptive-treatment-with-xonrid%C3%A2-a-medical-device-to-reduce-radiation-induced-dermatitis-in-head-and-neck-cancer-patients-receiving-curative-treatment-a-pilot-study
#7
Nicola Alessandro Iacovelli, Simona Naimo, Francesca Bonfantini, Anna Cavallo, Paolo Bossi, Carlo Fallai, Emanuele Pignoli, Salvatore Alfieri, Cristiana Bergamini, Federica Favales, Ester Orlandi
PURPOSE: The purpose of this study was to investigate efficacy, safety and tolerability of Xonrid®, a new medical device, in preventing radiation dermatitis associated with head and neck cancer (HNC) radiotherapy (RT). METHODS: In this monocentric, prospective pilot study, adult consecutive HNC patients who were planned to receive curative RT with or without chemotherapy were enrolled. Patients were instructed to apply Xonrid® on the irradiated area during treatment continuing until 2 weeks after the completion of RT or the development of severe skin toxicity...
January 20, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28108445/multi-rate-poisson-tree-processes-for-single-locus-species-delimitation-under-maximum-likelihood-and-markov-chain-monte-carlo
#8
P Kapli, S Lutteropp, J Zhang, K Kobert, P Pavlidis, A Stamatakis, T Flouri
MOTIVATION: In recent years, molecular species delimitation has become a routine approach for quantifying and classifying biodiversity. Barcoding methods are of particular importance in large-scale surveys as they promote fast species discovery and biodiversity estimates. Among those, distance-based methods are the most common choice as they scale well with large datasets; however, they are sensitive to similarity threshold parameters and they ignore evolutionary relationships. The recently introduced "Poisson Tree Processes" (PTP) method is a phylogeny-aware approach that does not rely on such thresholds...
January 19, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28108374/strategies-to-reduce-hospitalizations-of-children-with-medical-complexity-through-complex-care-expert-perspectives
#9
Ryan J Coller, Bergen B Nelson, Thomas S Klitzner, Adrianna A Saenz, Paul G Shekelle, Carlos F Lerner, Paul J Chung
OBJECTIVES: Interventions to reduce disproportionate hospital use among children with medical complexity (CMC) are needed. Our objective was to conduct a rigorous, structured process to develop intervention strategies aiming to reduce hospitalizations within a complex care program population. METHODS: A complex care medical home program used 1) semi-structured interviews of caregivers of CMC experiencing acute, unscheduled hospitalizations, and 2) literature review on preventing hospitalizations among CMC, to develop key drivers for lowering hospital utilization and link them with intervention strategies...
January 17, 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/28108337/cardiovascular-and-cerebrovascular-events-among-patients-receiving-omalizumab-pooled-analysis-of-patient-level-data-from-25-randomized-double-blind-placebo-controlled-clinical-trials
#10
Carlos Iribarren, Kenneth J Rothman, Mary S Bradley, Gillis Carrigan, Mark D Eisner, Hubert Chen
Among patients who participated in randomized clinical trials of omalizumab, no substantial overall increase in the risk of cardiovascular events was observed in the treatment arms compared with placebo. <29/35 words>.
January 17, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28108294/the-dimensional-reduction-method-for-identification-of-parameters-that-trade-off-due-to-similar-model-roles
#11
Shaun M Davidson, Paul D Docherty, Rua Murray
Parameter identification is an important and widely used process across the field of biomedical engineering. However, it is susceptible to a number of potential difficulties, such as parameter trade-off, causing premature convergence at non-optimal parameter values. The proposed Dimensional Reduction Method (DRM) addresses this issue by iteratively reducing the dimension of hyperplanes where trade off occurs, and running subsequent identification processes within these hyperplanes. The DRM was validated using clinical data to optimize 4 parameters of the widely used Bergman Minimal Model of glucose and insulin kinetics, as well as in-silico data to optimize 5 parameters of the Pulmonary Recruitment (PR) Model...
January 17, 2017: Mathematical Biosciences
https://www.readbyqxmd.com/read/28108228/a-preliminary-study-of-endocannabinoid-system-regulation-in-psychosis-distinct-alterations-of-cnr1-promoter-dna-methylation-in-patients-with-schizophrenia
#12
Claudio D'Addario, Vincenzo Micale, Martina Di Bartolomeo, Tibor Stark, Mariangela Pucci, Alexandra Sulcova, Mariacarlotta Palazzo, Zuzana Babinska, Laura Cremaschi, Filippo Drago, A Carlo Altamura, Mauro Maccarrone, Bernardo Dell'Osso
Compelling evidence supports the involvement of the endocannabinoid system (ECS) in psychosis vulnerability. We here evaluated the transcriptional regulation of ECS components in human peripheral blood mononuclear cells (PBMCs) obtained from subjects suffering from bipolar disorder, major depressive disorder and schizophrenia, focusing in particular on the effects of DNA methylation. We observed selective alterations of DNA methylation at the promoter of CNR1, the gene coding for the type-1 cannabinoid receptor, in schizophrenic patients (N=25) with no changes in any other disorder...
January 17, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28108211/user-centered-design-improves-the-usability-of-drug-drug-interaction-alerts-experimental-comparison-of-interfaces
#13
Daniel R Luna, Daniel A Rizzato Lede, Carlos M Otero, Marcelo R Risk, Fernán González Bernaldo de Quirós
Clinical Decision Support Systems can alert health professionals about drug interactions when they prescribe medications. The Hospital Italiano de Buenos Aires in Argentina developed an electronic health record with drug-drug interaction alerts, using traditional software engineering techniques and requirements. Despite enhancing the drug-drug interaction knowledge database, the alert override rate of this system was very high. We redesigned the alert system using user-centered design (UCD) and participatory design techniques to enhance the drug-drug interaction alert interface...
January 17, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28108178/reference-values-for-peak-exercise-cardiac-output-in-healthy-individuals
#14
Piergiuseppe Agostoni, Carlo Vignati, Piero Gentile, Costanza Boiti, Stefania Farina, Elisabetta Salvioni, Massimo Mapelli, Damiano Magrì, Stefania Paolillo, Nicoletta Corrieri, Gianfranco Sinagra, Gaia Cattadori
AIMS: Cardiac output (Q) is a key parameter in the assessment of cardiac function, its measurement being crucial for the diagnosis, treatment and prognostic evaluation of all heart diseases. Until recently, Q determination at peak exercise has been possible through invasive methods, so that normal values were obtained in studies based on small populations. METHODS AND RESULTS: Nowadays, peak Q can be measured noninvasively by means of inert gas rebreathing technique (IGR)...
January 17, 2017: Chest
https://www.readbyqxmd.com/read/28108113/current-understanding-of-the-hypothalamic-ghrelin-pathways-inducing-appetite-and-adiposity
#15
REVIEW
Omar Al Massadi, Miguel López, Matthias Tschöp, Carlos Diéguez, Ruben Nogueiras
Ghrelin is a multifaceted regulator of metabolism. Ghrelin regulates energy balance in the short term via induction of appetite and in the long term via increased body weight and adiposity. Recently, several central pathways modulating the metabolic actions of ghrelin were unmasked, and it was shown to act through different hypothalamic nuclei to induce feeding. Ghrelin also modulates glucose homeostasis, but the central mechanisms responsible for this action have not been studied in detail. Although ghrelin also acts through extrahypothalamic areas to promote feeding, this review specifically dissects hypothalamic control of ghrelin's orexigenic and adipogenic actions and presents current understanding of the intracellular ghrelin orexigenic pathways, including their dependence on other relevant systems implicated in energy balance...
January 17, 2017: Trends in Neurosciences
https://www.readbyqxmd.com/read/28108031/ifpa-meeting-2016-workshop-report-i-genomic-communication-bioinformatics-trophoblast-biology-and-transport-systems
#16
Christiane Albrecht, Julie C Baker, Cassidy Blundell, Shawn L Chavez, Lucia Carbone, Larry Chamley, Roberta L Hannibal, Nick Illsley, Peter Kurre, Louise C Laurent, Charles McKenzie, Diana Morales-Prieto, Priyadarshini Pantham, Alison Paquette, Katie Powell, Nathan Price, Balaji M Rao, Yoel Sadovsky, Carlos Salomon, Geetu Tuteja, Samantha Wilson, P F O'Tierney-Ginn
Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialized topics. At IFPA meeting 2016 there were twelve themed workshops, four of which are summarized in this report. These workshops covered innovative technologies applied to new and traditional areas of placental research: 1) genomic communication; 2) bioinformatics; 3) trophoblast biology and pathology; 4) placental transport systems.
January 11, 2017: Placenta
https://www.readbyqxmd.com/read/28108000/evaluating-and-modeling-the-effects-of-surface-sampling-factors-on-the-recovery-of-organic-chemical-attribution-signatures-using-the-accelerated-diffusion-sampler-and-solvent-extraction
#17
Kai-For Mo, Alejandro Heredia-Langner, Carlos G Fraga
In this study, an experimental design matrix was created and executed to test the effects of various real-world factors on the ability of (1) the accelerated diffusion sampler with solid phase micro-extraction (ADS-SPME) and (2) solvent extraction to capture organic chemical attribution signatures (CAS) from dimethyl methylphosphonate (DMMP) spiked onto painted wall board (PWB) surfaces. The DMMP CAS organic impurities sampled by ADS-SPME and solvent extraction were analyzed by gas chromatography/mass spectrometry (GC/MS)...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107940/incorporation-of-zeolitic-imidazolate-framework-zif-8-derived-nanoporous-carbons-in-methacrylate-polymeric-monoliths-for-capillary-electrochromatography
#18
Enrique Javier Carrasco-Correa, Andrea Martínez-Vilata, José Manuel Herrero-Martínez, José B Parra, Fernando Maya, Victor Cerdà, Carlos Palomino Cabello, Gemma Turnes Palomino, Frantisek Svec
A series of metal organic frameworks-derived nanoporous carbons originating from zeolitic imidazolate framework-8 (ZIF-8) crystals as precursors have been prepared via varying the preparation conditions. The ZIF-8-derived carbons were subsequently admixed in the methacrylate monomers containing polymerization mixtures and polymerized to obtain monolithic columns for capillary electrochromatography (CEC). The effect of particle size and content of the ZIF-8-derived carbon materials in the polymerization mixture on the performance of the hybrid monolithic columns was investigated in detail...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107771/a-prospective-study-of-maternal-fetal-and-neonatal-outcomes-in-the-setting-of-cesarean-section-in-low-and-middle-income-countries
#19
Margo S Harrison, Omrana Pasha, Sarah Saleem, Sumera Ali, Elwyn Chomba, Waldemar A Carlo, Ana L Garces, Nancy F Krebs, K Michael Hambidge, Shivaprasad S Goudar, Bhala Kodkany, Sangappa Dhaded, Richard J Derman, Archana Patel, Patricia L Hibberd, Fabian Esamai, Edward A Liechty, Janet L Moore, Dennis Wallace, Elizabeth M McClure, Menachem Miodovnik, Marion Koso-Thomas, Jose Belizan, Robert L Goldenberg
Cesarean section (CS) rates are increasing globally with an unclear effect on pregnancy outcomes. The study objective was to quantify maternal and perinatal morbidity and mortality in low- and middle-income countries associated with CS compared to vaginal delivery (VD) both within and across sites MATERIAL AND METHODS: A prospective population-based study including home and facility births in 337,153 women with a VD and 47,308 women with a CS from 2010 to 2015 was performed in Guatemala, India, Kenya, Pakistan, Zambia, and Democratic Republic of Congo...
January 20, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28107725/photo-release-of-nitrous-oxide-from-the-hyponitrite-ion-studied-by-infrared-spectroscopy-evidence-for-the-generation-of-a-cobalt-n2o-complex-experimental-and-dft-calculations
#20
M Elizabeth Chacón Villalba, Carlos A Franca, Jorge A Güida
The solid state photolysis of sodium, silver and thallium hyponitrite (M2N2O2, M=Na, Ag, Tl) salts and a binuclear complex of cobalt bridged by hyponitrite ([Co(NH3)5-N(O)-NO-Co(NH3)5](4+)) were studied by irradiation with visible and UV light in the electronic absorption region. The UV-visible spectra for free hyponitrite ion and binuclear complex of cobalt were interpreted in terms of Density Functional Theory calculations in order to explain photolysis behavior. The photolysis of each compound depends selectively on the irradiation wavelength...
January 10, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
keyword
keyword
65324
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"