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Reflective functioning

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https://www.readbyqxmd.com/read/29334490/differential-impact-of-local-and-regional-aortic-stiffness-on-left-ventricular-remodeling-a-cardiovascular-magnetic-resonance-study
#1
Thiago Quinaglia, Mourad Z Bensalah, Emilie Bollache, Nadjia Kachenoura, Gilles Soulat, Pierre Boutouyrie, Stéphane Laurent, Elie Mousseaux
BACKGROUND: Left ventricular (LV) remodeling and aortic stiffness have independent predictive value for all causes and cardiovascular mortality. Because elastic properties of the arterial wall vary along the aortic pathway, we hypothesized that local and regional aortic stiffness could differently impact on LV remodeling. METHODS AND RESULTS: Regional aortic stiffness was determined from carotid-femoral pulse wave velocity (cfPWV) measured by aplanation tonometry...
January 13, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29334356/p53-suppresses-mutagenic-rad52-and-pol%C3%AE-pathways-by-orchestrating-dna-replication-restart-homeostasis
#2
Sunetra Roy, Karl-Heinz Tomaszowski, Jessica W Luzwick, Soyoung Park, Jun Li, Maureen Murphy, Katharina Schlacher
Classically, p53 tumor suppressor acts in transcription, apoptosis, and cell cycle arrest. Yet, replication-mediated genomic instability is integral to oncogenesis, and p53 mutations promote tumor progression and drug-resistance. By delineating human and murine separation-of-function p53 alleles, we find that p53 null and gain-of-function (GOF) mutations exhibit defects in restart of stalled or damaged DNA replication forks driving genomic instability genetically separable from transcription activation. By assaying protein-DNA fork interactions in single cells, we unveil a p53-MLL3-enabled recruitment of MRE11 DNA replication restart nuclease...
January 15, 2018: ELife
https://www.readbyqxmd.com/read/29334192/digitalizing-self-assembled-chiral-superstructures-for-optical-vortex-processing
#3
Peng Chen, Ling-Ling Ma, Wei Duan, Ji Chen, Shi-Jun Ge, Zhi-Han Zhu, Ming-Jie Tang, Ran Xu, Wei Gao, Tao Li, Wei Hu, Yan-Qing Lu
Cholesteric liquid crystal (CLC) chiral superstructures exhibit unique features; that is, polychromatic and spin-determined phase modulation. Here, a concept for digitalized chiral superstructures is proposed, which further enables the arbitrary manipulation of reflective geometric phase and may significantly upgrade existing optical apparatus. By encoding a specifically designed binary pattern, an innovative CLC optical vortex (OV) processor is demonstrated. Up to 25 different OVs are extracted with equal efficiency over a wavelength range of 116 nm...
January 15, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29334155/response-selection-codes-in-neurophysiological-data-predict-conjoint-effects-of-controlled-and-automatic-processes-during-response-inhibition
#4
Witold X Chmielewski, Moritz Mückschel, Christian Beste
The inhibition of prepotent responses is a requirement for goal-directed behavior and several factors determine corresponding successful response inhibition processes. One factor relates to the degree of automaticity of pre-potent response tendencies and another factor relates to the degree of cognitive control that is exerted during response inhibition. However, both factors can conjointly modulate inhibitory control. Cognitive theoretical concepts suggest that codings of stimulus-response translations may underlie such conjoint effects...
January 15, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29334019/chemical-stabilization-of-polymers-implications-for-dermal-exposure-to-additives
#5
N Bartsch, M Girard, L Schneider, V Van De Weijgert, A Wilde, O Kappenstein, B Vieth, C Hutzler, A Luch
Technical benefits of additives in polymers stand in marked contrast to their associated health risks. Here, a multi-analyte method based on gas chromatography coupled to tandem mass spectrometry (GC-MS/MS) was developed to quantify polymer additives in complex matrices such as low-density polyethylene (LDPE) and isolated human skin layers after dermal exposure ex vivo. That way both technical aspects and dermal exposure were investigated. The effects of polymer additivation on the material were studied using the example of LDPE...
January 15, 2018: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/29333801/efficacy-of-the-regent-suit-based-rehabilitation-on-gait-emg-patterns-in-hemiparetic-subjects-a-pilot-study
#6
Luigi Iuppariello, Giovanni D'Addio, Maria Romano, Paolo Bifulco, Nicola Pappone, Bernardo Lanzillo, Mario Cesarelli
BACKGROUND: The recovery of the functional limb mobility of patients with cerebral damages can take great benefit of the role offered by proprioceptive rehabilitation. Recently have been developed a special Regent Suit (RS) for rehabilitative applications. Actually, there are preliminary studies which describes the effects of RS on gait recovery of stroke patients in acute stage, but none in chronic stage. Moreover, it is known that motor recovery does not always reflect improvements of the muscle activity and coactivity...
January 11, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29333060/optimising-human-community-sizes
#7
Robin I M Dunbar, Richard Sosis
We examine community longevity as a function of group size in three historical, small scale agricultural samples. Community sizes of 50, 150 and 500 are disproportionately more common than other sizes; they also have greater longevity. These values mirror the natural layerings in hunter-gatherer societies and contemporary personal networks. In addition, a religious ideology seems to play an important role in allowing larger communities to maintain greater cohesion for longer than a strictly secular ideology does...
January 2018: Evolution and Human Behavior: Official Journal of the Human Behavior and Evolution Society
https://www.readbyqxmd.com/read/29332921/early-diastolic-left-ventricular-relaxation-in-normal-neonates-is-influenced-by-ventricular-stiffness-and-longitudinal-systolic-function
#8
Yukako Homma, Yasunobu Hayabuchi, Tomomasa Terada, Miki Inoue, Kazuhiro Mori
Tissue Doppler velocity during early diastole (e') is one of the most feasible and reproducible echocardiographic assessments to reflect active relaxation of the left ventricle. Although several reports have described the mechanisms of temporal diastolic dysfunction in the early neonatal period, factors influencing diastolic function have not been determined. The purpose of this study was to elucidate factors significantly influencing e' in the early neonatal period.A total of 179 consecutive normal neonates underwent echocardiographic studies performed at 0 days and 5-10 days after birth...
January 15, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29332730/biomechanical-factors-associated-with-running-economy-and-performance-of-elite-kenyan-distance-runners-a-systematic-review
#9
REVIEW
Nassib Tawa, Quinette Louw
BACKGROUND: Running economy (RE) is a determinant of performance in endurance sports and is a complex multi-factorial measure which reflects the combined functioning of bio-mechanical, neuro-muscular, metabolic and cardio-respiratory factors some of which are hereditary or adapt to coaching. Kenyan distance runners have dominated major global events with their unmatched performance for decades and this phenomenon has prompted several investigations aimed at establishing possible factors associated with their performance...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29332310/advances-and-current-challenges-in-calcium-signaling
#10
REVIEW
Jörg Kudla, Dirk Becker, Erwin Grill, Rainer Hedrich, Michael Hippler, Ursula Kummer, Martin Parniske, Tina Romeis, Karin Schumacher
Content I. II. III. IV. V. VI. VII VIII IX X XI ORCID References SUMMARY: Temporally and spatially defined changes in Ca2+ concentration in distinct compartments of cells represent a universal information code in plants. Recently, it has become evident that Ca2+ signals not only govern intracellular regulation but also appear to contribute to long distance or even organismic signal propagation and physiological response regulation. Ca2+ signals are shaped by an intimate interplay of channels and transporters, and during past years important contributing individual components have been identified and characterized...
January 14, 2018: New Phytologist
https://www.readbyqxmd.com/read/29332091/the-association-among-default-mode-network-functional-connectivity-mentalization-and-psychopathology-in-a-nonclinical-sample-an-eloreta-study
#11
Benedetto Farina, Giacomo Della Marca, Giulia Maestoso, Noemi Amoroso, Enrico Maria Valenti, Giuseppe Alessio Carbone, Chiara Massullo, Anna Contardi, Claudio Imperatori
AIMS: We investigated default mode network (DMN) electroencephalography (EEG) functional connectivity differences between individuals with self-reported high mentalization capability and low psychopathological symptoms, versus participants with mentalization impairments and high psychopathological symptoms. METHODS: Forty-nine students (35 women) with a mean age of 22.92 ± 2.53 years were administered the Mentalization Questionnaire (MZQ) and the Symptom Checklist-90-Revised...
January 13, 2018: Psychopathology
https://www.readbyqxmd.com/read/29331931/resting-state-fmri-signals-in-offspring-of-parents-with-bipolar-disorder-at-the-high-risk-and-ultra-high-risk-stages-and-their-relations-with-cognitive-function
#12
Kangguang Lin, Robin Shao, Rui Lu, Kun Chen, Weicong Lu, Ting Li, Jiehua Kong, Kwok-Fai So, Guiyun Xu
BACKGROUND: Bipolar disorder (BD) has been associated with dysfunctional resting-state brain functioning. However, it is still not known whether the aberrant functioning occurs and predict cognitive functioning before illness onset. AIMS: We examined the resting-state regional and network dysfunctioning, and their correlates with neurocognitive performance, in the high-risk (HR) and ultra-high-risk (UHR) stages of bipolar disorder. METHODS: Using amplitude of low-frequency fluctuations (ALFF), region homogeneity (ReHo) and hypothesis-driven region-of-interest (ROI)-based connectivity, we examined resting-state fMRI data of 8- to 25-year-old healthy offspring (HR, n = 28) and offspring with subthreshold syndromes (UHR, n = 22) of a BD parent, and age-matched healthy controls without any personal or family psychopathology (HC, n = 46)...
January 8, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29331777/comparing-the-antifouling-effects-of-activated-carbon-and-tio2-in-ultrafiltration-membrane-development
#13
Qianyu Liu, Shaobin Huang, Yongqing Zhang, Shuaifei Zhao
We use activated carbon (AC) and titanium oxide (TiO2) nanomaterials as the additives to prepare four polyvinylidene fluoride (PVDF) based ultrafiltration membranes by nonsolvent induced phase separation. The surface properties (pore size, porosity, hydrophilicity and roughness) of the membranes are characterized by scanning electron microscopy, water contact angle measurement, and atomic force microscopy. The chemical properties of the membranes are evaluated by Fourier transform infrared spectroscopy with attenuated total reflection and X-ray diffraction...
January 6, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29331624/comprehensive-geriatric-assessment-in-the-older-adult-with-cancer-a-review
#14
REVIEW
Catalina Hernandez Torres, Tina Hsu
CONTEXT: The number of older adults with cancer is expected to increase rapidly in the upcoming decades. Aging is heterogeneous and chronological age is often not reflective of biological age. A comprehensive geriatric assessment (CGA) is an in-depth assessment of multiple domains of health that results in better assessment of a patient's overall health and fitness and allows directed intervention to improve patient outcomes. OBJECTIVE: To review the value of CGA for older adults with cancer, CGA composition and tools that can be utilized, and the feasibility of including CGA in oncologic practice...
January 10, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29331169/the-introduction-of-simple-cardiorespiratory-fitness-testing-in-overweight-obese-type-2-diabetics-a-pilot-study
#15
Ľubica Cibičková, David Karásek, Jiří Lukeš, Norbert Cibiček
BACKGROUND: Low level of cardiorespiratory fitness has been recognized as an important independent and modifiable risk factor of increased morbidity and mortality. However, in standard outpatient settings, patients are not routinely screened for fitness and advantages of such testing for the management of type 2 diabetes have not been defined. Aim To describe the toleration of a fast, simple and practicable fitness test (2-min step-in-place test) by overweight/obese type 2 diabetics and their performance indicated by 2-min step-in-place test score (STS)...
January 14, 2018: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29331152/functioning-before-and-after-a-major-depressive-episode-pre-existing-vulnerability-or-scar-a-prospective-three-wave-population-based-study
#16
E H Bos, M Ten Have, S van Dorsselaer, B F Jeronimus, R de Graaf, P de Jonge
BACKGROUND: The vulnerability hypothesis suggests that impairments after remission of depressive episodes reflect a pre-existing vulnerability, while the scar hypothesis proposes that depression leaves residual impairments that confer risk of subsequent episodes. We prospectively examined vulnerability and scar effects in mental and physical functioning in a representative Dutch population sample. METHODS: Three waves were used from the Netherlands Mental Health Survey and Incidence Study-2, a population-based study with a 6-years follow-up...
January 14, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29330959/non-destructive-determination-of-muscle-architectural-variables-through-the-use-of-dicect
#17
Edwin Dickinson, Heiko Stark, Kornelius Kupczik
The fascicular architecture of skeletal muscle dictates functional parameters such as force production and contractile velocity. Muscle microarchitecture is typically determined by means of manual dissection, a technique that is inherently destructive to specimens. Furthermore, fascicle lengths and pennation angles are commonly assessed at only a limited number of sampling sites per muscle. We present the results of a digital technique to non-destructively assess muscle architectural variables for three jaw-adductor muscles within a specimen of the cercopithecine primate Macaca fascicularis (crab-eating macaque)...
February 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29330918/leptosphaeria-maculans-avrlm9-a-new-player-in-the-game-of-hide-and-seek-with-avrlm4-7
#18
Kaveh Ghanbarnia, Lisong Ma, Nicholas J Larkan, Parham Haddadi, W G Dilantha Fernando, M Hossein Borhan
Blackleg disease of Brassica napus caused by Leptosphaeria maculans (Lm) is largely controlled by deploying race-specific resistance (R) genes. However, selection pressure exerted by R genes causes Lm to adapt and give rise to new virulent strains through mutation and deletion of effector genes. Therefore, knowledge of effector gene function is necessary for effective management of the disease. Here we report cloning of Lm effector AvrLm9 that is recognised by the resistance gene Rlm9 in B. napus cultivar Goéland...
January 13, 2018: Molecular Plant Pathology
https://www.readbyqxmd.com/read/29330681/verification-of-nonwords-the-baseword-frequency-effect-in-children-s-pseudohomophone-reading
#19
Simon P Tiffin-Richards, Sascha Schroeder
In this study, we investigated the baseword frequency effect in children and its implications for models of visual word recognition. The baseword frequency effect reflects the finding that response latencies in the lexical decision task to nonwords derived from high-frequency basewords (e.g., GREAN derived from GREEN) are shorter than for those derived from low-frequency basewords (e.g., SLEAT derived from SLEET). Importantly, the baseword frequency effect presents a challenge to current activation-based models of visual word recognition...
January 12, 2018: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/29330134/a-supplementary-functional-connectivity-microstate-attached-to-the-default-mode-network-in-depression-revealed-by-resting-state-magnetoencephalography
#20
Siqi Zhang, Shui Tian, Mohammad Ridwan Chattun, Hao Tang, Rui Yan, Kun Bi, Zhijian Yao, Qing Lu
Default mode network (DMN) has discernable involvement in the representation of negative, self-referential information in depression. Both increased and decreased resting-state functional connectivity between the anterior and posterior DMN have been observed in depression. These conflicting connectivity differences necessitated further exploration of the resting-state DMN dysfunction in depression. Hence, we investigated the time-varying dynamic interactions within the DMN via functional connectivity microstates in a sub-second level...
January 9, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
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