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Preventive nephrology

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https://www.readbyqxmd.com/read/29146140/patient-experiences-of-dietary-management-in-chronic-kidney-disease-a-focus-group-study
#1
Jaimon T Kelly, Katrina L Campbell, Tammy Hoffmann, Dianne P Reidlinger
OBJECTIVE: People with chronic kidney disease (CKD) contend with complex dietary recommendations. The challenge in practice is for clinicians to provide individualized support with the frequency and consistency required to sustain dietary changes. This study aimed to describe the experiences of patients with managing dietary recommendations, including their perspectives on the potential to use telehealth to support dietary management in CKD. DESIGN: Focus group study...
November 14, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29116680/emergency-department-utilization-among-kidney-transplant-recipients-in-the-united-states
#2
Brendan P Lovasik, Rebecca Zhang, Jason M Hockenberry, Justin D Schrager, Stephen O Pastan, Andrew B Adams, Sumit Mohan, Christian P Larsen, Rachel E Patzer
Patients with End Stage Renal Disease (ESRD) use the emergency department (ED) at a 6-fold higher rate than U.S. adults. No national studies have described ED utilization rates among kidney transplant (KTx) recipients, and the factors associated with higher ED utilization. We examined a cohort of 132,725 adult KTx recipients in the United States Renal Data System (2005-2013). ED visits, hospitalization, and outpatient nephrology visits were obtained from Medicare claims databases. Nearly half (46.1%) of KTx recipients had at least one ED visit (1...
November 8, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/29098756/reducing-the-risk-of-healthcare-associated-infections-through-lean-six-sigma-the-case-of-the-medicine-areas-at-the-federico-ii-university-hospital-in-naples-italy
#3
Giovanni Improta, Mario Cesarelli, Paolo Montuori, Liberatina Carmela Santillo, Maria Triassi
RATIONALE, AIMS, AND OBJECTIVES: Lean Six Sigma (LSS) has been recognized as an effective management tool for improving healthcare performance. Here, LSS was adopted to reduce the risk of healthcare-associated infections (HAIs), a critical quality parameter in the healthcare sector. METHODS: Lean Six Sigma was applied to the areas of clinical medicine (including general medicine, pulmonology, oncology, nephrology, cardiology, neurology, gastroenterology, rheumatology, and diabetology), and data regarding HAIs were collected for 28,000 patients hospitalized between January 2011 and December 2016...
November 3, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28981230/-diagnosis-and-treatment-of-nephrolithiasis-and-prevention-of-recurrences
#4
I Simon, F Legrand, J M Des Grottes, F Cotton, J Nortier, T Roumeguère
despite fluctuations, the prevalence of nephrolithiasis has significantly increased during the last decades in industrialized nations worldwide (1 to 15 %), which has a significant impact on the cost of healthcare. This increased prevalence is mainly explained by diet modifications. Environmental, metabolic and genetic factors may also influence the formation of kidney stones. As a consequence, the medical management of this disease is preferentially multidisciplinary and involves urologists, nephrologists, radiologists, biologists and dietitians...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28980667/thrombotic-microangiopathy-induced-by-interferon-beta-in-patients-with-multiple-sclerosis-three-cases-treated-with-eculizumab
#5
Marco Allinovi, Calogero Lino Cirami, Leonardo Caroti, Giulia Antognoli, Silvia Farsetti, Maria Pia Amato, Enrico Eugenio Minetti
BACKGROUND: Interferon-beta (IFN-beta) is one of the most widely prescribed medications for relapsing-remitting multiple sclerosis (RRMS). IFN-related thrombotic microangiopathy (TMA) is a rare but severe complication, with a fulminant clinical onset and a possibly life-threatening outcome that may occur years after a well-tolerated treatment with IFN. Most patients evolve rapidly to advanced chronic kidney disease and eventually to renal failure. METHODS: We performed a retrospective analysis of TMA cases diagnosed and managed in our Nephrology Department from 2010 to 2015, and performed a literature review of IFN-beta-induced TMA...
October 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28964571/fractures-in-patients-with-ckd-diagnosis-treatment-and-prevention-a-review-by-members-of-the-european-calcified-tissue-society-and-the-european-renal-association-of-nephrology-dialysis-and-transplantation
#6
REVIEW
Ana Pimentel, Pablo Ureña-Torres, M Carola Zillikens, Jordi Bover, Martine Cohen-Solal
Mineral and bone disease is omnipresent in patients with chronic kidney disease (CKD) and leads to a diverse range of clinical manifestations, including bone pain and fractures. The accumulation of traditional clinical risk factors, in addition to those related to CKD, enhances the risk of comorbidity and mortality. Despite significant advances in understanding bone disease in CKD, most clinical and biochemical targets used in clinical practice remain controversial, resulting in an undermanagement of bone fragility...
September 27, 2017: Kidney International
https://www.readbyqxmd.com/read/28963826/-italian-health-centers-and-web-marketing-strategy-necessary-improvements-even-in-nephrology
#7
Maria Rinaldi Miliani, Antonio Barracca, Giuseppe Quintaliani
The complete digitalization of the health system is an objective that Italy, from 2014, is pursuing with great difficulty, spurred by the many European initiatives dedicated to it. Despite the social and cultural background seems to be clearly ready for an application of the renewal strategies, e-Health and m-Health are struggling to get off the ground throughout the territory. The main difficulties are find at local level and don't spare any medical discipline, nephrology included. The characteristics of the official websites belonging to the local health centers demonstrate it...
September 28, 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28958905/-uro-and-nephrotoxic-effects-of-drugs-of-abuse-literature-review-and-pharmaco-epidemiological-survey-in-france-and-in-the-marseille-area
#8
Marion Gully, Élisabeth Frauger, Michel Spadari, Liselotte Pochard, Vanessa Pauly, Fanny Romain, Bertrand Gondouin, Marion Sallée, Julie Moussi-Frances, Stéphane Burtey, Bertrand Dussol, Laurent Daniel, Joëlle Micallef, Noémie Jourde-Chiche
A great diversification of drugs of abuse has been observed in recent years, both in the populations using them and in the types of drugs. Although dependency and psychiatric disorders associated with the abuse of these substances is well known, somatic complications, uro-nephrotoxicity in particular, are less recognized. We propose here an overview of the products used by drugs abusers in France, through the analysis of the national pharmaco-epidemiological study Observation des produits psychotropes illicites ou détournés de leur utilisation médicamenteuse (OPPIDUM)...
September 25, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28943270/investigation-of-nosocomial-pneumocystis-infections-usefulness-of-longitudinal-screening-of-epidemic-and-post-epidemic-pneumocystis-genotypes
#9
G Nevez, S Le Gal, N Noel, A Wynckel, A Huguenin, Y Le Govic, L Pougnet, M Virmaux, D Toubas, O Bajolet
BACKGROUND: Twenty-five patients, of whom 22 were renal transplant recipients, developed Pneumocystis jirovecii infections at the nephrology department of Reims University Hospital (France) from September 2008 to October 2009, whereas only four sporadic cases had been diagnosed in this department over the 14 previous years. AIM: This outbreak was investigated by analysing patient encounters and P. jirovecii types. METHODS: A transmission map was drawn up...
September 21, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28941764/kdoqi-us-commentary-on-the-2017-kdigo-clinical-practice-guideline-update-for-the-diagnosis-evaluation-prevention-and%C3%A2-treatment-of-chronic-kidney-disease-mineral-and-bone%C3%A2-disorder-ckd-mbd
#10
Tamara Isakova, Thomas L Nickolas, Michelle Denburg, Sri Yarlagadda, Daniel E Weiner, Orlando M Gutiérrez, Vinod Bansal, Sylvia E Rosas, Sagar Nigwekar, Jerry Yee, Holly Kramer
Chronic kidney disease-mineral and bone disorder (CKD-MBD) encompasses laboratory and bone abnormalities and vascular calcification and has deleterious effects on clinical outcomes. KDOQI (Kidney Disease Outcomes Quality Initiative), an initiative of the National Kidney Foundation, addressed this issue with the publication of a clinical practice guideline for bone metabolism and disease in CKD in 2003, and 2 years later, a new definition and classification scheme for CKD-MBD was developed following a KDIGO (Kidney Disease: Improving Global Outcomes) Controversies Conference...
September 20, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28941763/oral-anticoagulants-to-prevent-stroke-in-nonvalvular-atrial-fibrillation-in-patients-with-ckd-stage-5d-an-nkf-kdoqi-controversies-report
#11
Vinod K Bansal, Charles A Herzog, Mark J Sarnak, Michael J Choi, Ravindra Mehta, Bernard G Jaar, Michael V Rocco, Holly Kramer
Stroke risk may be more than 3-fold higher among patients with chronic kidney disease stage 5D (CKD-5D) compared to the general population, with the highest stroke rates noted among those 85 years and older. Atrial fibrillation (AF), a strong risk factor for stroke, is the most common arrhythmia and affects >7% of the population with CKD-5D. Warfarin use is widely acknowledged as an important intervention for stroke prevention with nonvalvular AF in the general population. However, use of oral anticoagulants for stroke prevention in patients with CKD-5D and nonvalvular AF continues to be debated by the nephrology community...
September 20, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28938511/-obesity-and-kidney-disease-renal-consequences-of-an-epidemic
#12
Helmut Schiffl, Susanne Maria Lang
Overweight and obesity are widespread in the German population, affecting not only adults but also a significant number of children and adolescents. The risk to develop chronic kidney disease is markedly increased in overweight or adipose children, adolescents and adults.Overweight and obesity induced risk factors have a direct impact on the development of chronic renal disease (obesity-associated focal segmental glomerulosclerosis). They accelerate the progression of coexistent nephropathies (diabetic or hypertensive nephropathy, primary glomerulonephritides) and are independent risk factors for the development of acute kidney injury in critically ill patients...
September 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28915908/advances-in-paediatrics-in-2016-current-practices-and-challenges-in-allergy-autoimmune-diseases-cardiology-endocrinology-gastroenterology-infectious-diseases-neonatology-nephrology-neurology-nutrition-pulmonology
#13
REVIEW
Carlo Caffarelli, Francesca Santamaria, Dora Di Mauro, Carla Mastrorilli, Silvia Montella, Sergio Bernasconi
This review reports main progresses in various pediatric issues published in Italian Journal of Pediatrics and in international journals in 2016. New insights in clinical features or complications of several disorders may be useful for our better understanding. They comprise severe asthma, changing features of lupus erythematosus from birth to adolescence, celiac disease, functional gastrointestinal disorders, Moebius syndrome, recurrent pneumonia. Risk factors for congenital heart defects, Kawasaki disease have been widely investigated...
September 16, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28915657/the-prevalence-subtypes-and-associated-factors-of-hyperuricemia-in-lupus-nephritis-patients-at-chronic-kidney-disease-stages-1-3
#14
Simeng Liu, Yijun Gong, Hong Ren, Wen Zhang, Xiaonong Chen, Tong Zhou, Xiao Li, Nan Chen
There is a high prevalence of hyperuricemia (HUA) in the chronic kidney disease (CKD) population. However, there's a dearth of research on HUA's prevalence, subtypes, early detection, and treatment strategies of HUA in lupus nephritis (LN) patients. The aim of this study is to address these knowledge gaps. LN patients presenting to the Department of Nephrology at Shanghai Rui Jin Hospital from January 2011 to January 2016 were recruited. The effective sample size was derived using the power analysis. The demographic, clinical and laboratory characteristics of the LN patients with HUA were compared with those of patients without HUA...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28877866/european-evidence-based-recommendations-for-the-diagnosis-and-treatment-of-childhood-onset-lupus-nephritis-the-share-initiative
#15
Noortje Groot, Nienke de Graeff, Stephen D Marks, Paul Brogan, Tadej Avcin, Brigitte Bader-Meunier, Pavla Dolezalova, Brian M Feldman, Isabelle Kone-Paut, Pekka Lahdenne, Liza McCann, Seza Özen, Clarissa A Pilkington, Angelo Ravelli, Annet van Royen-Kerkhof, Yosef Uziel, Bas J Vastert, Nico M Wulffraat, Michael W Beresford, Sylvia Kamphuis
Lupus nephritis (LN) occurs in 50%-60% of patients with childhood-onset systemic lupus erythematosus (cSLE), leading to significant morbidity. Timely recognition of renal involvement and appropriate treatment are essential to prevent renal damage. The Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) initiative aimed to generate diagnostic and management regimens for children and adolescents with rheumatic diseases including cSLE. Here, we provide evidence-based recommendations for diagnosis and treatment of childhood LN...
December 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28873969/clinical-practice-recommendations-for-native-vitamin-d-therapy-in-children-with-chronic-kidney-disease-stages-2-5-and-on-dialysis
#16
Rukshana Shroff, Mandy Wan, Evi V Nagler, Sevcan Bakkaloglu, Dagmar-C Fischer, Nicholas Bishop, Mario Cozzolino, Justine Bacchetta, Alberto Edefonti, Constantinos J Stefanidis, Johan Vande Walle, Dieter Haffner, Günter Klaus, Claus Peter Schmitt
Vitamin D deficiency is widely prevalent and often severe in children and adults with chronic kidney disease (CKD). Although native vitamin D {25-hydroxyvitamin D [25(OH)D]} is thought to have pleiotropic effects on many organ systems, its skeletal effects have been most widely studied. The 25(OH)D deficiency is causally linked with rickets and fractures in healthy children and those with CKD, contributing to the CKD-mineral and bone disorder (MBD) complex. There are few studies to provide evidence for vitamin D therapy or guidelines for its use in CKD...
July 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28869953/acute-kidney-injury-following-ingestion-of-henna-leaf-extract-a-case-report-from-myanmar
#17
Yi Yi Khine
Alternative medicine is gaining popularity worldwide. In Asia, particularly Southeast Asia, herbal medicine plays an important role in healthcare. A 34-year-old man from Yangon, Myanmar, was admitted to the medical ward of our hospital after ingesting a herbal remedy of boiled henna leaves (Dan Ywet in Burmese). He developed hemoglobinuria leading to acute kidney injury (AKI). The insult was severe, and he underwent 5 sessions of hemodialysis. His condition improved and within 7 weeks of injury, he made a full recovery...
2017: Blood Purification
https://www.readbyqxmd.com/read/28868291/rare-renal-diseases-can-be-used-as-tools-to-investigate-common-kidney-disorders
#18
REVIEW
Mariadelina Simeoni, Sara Damiano, Giovanna Capolongo, Francesco Trepiccione, Miriam Zacchia, Giorgio Fuiano, Giovambattista Capasso
BACKGROUND: The prevention and slowing of chronic kidney disease still represent major challenges in nephrology. To this end, a major contribution may come from the extensive knowledge on the molecular pathways involved in the pathogenesis of rare kidney diseases, since it is now possible to shed light on several aspects of these pathologies thanks to the introduction of new technologies, including next-generation sequencing. SUMMARY: In steroid-resistant nephrotic patients, a genetic background has been demonstrated in both children and adults; individualized mutations have been correlated with glomerular filtration barrier alterations...
July 2017: Kidney Diseases
https://www.readbyqxmd.com/read/28855226/antibiotics-for-performing-voiding-cystourethrogram-a-randomised-control-trial
#19
Rajiv Sinha, Subhasis Saha, Biplab Maji, Yincent Tse
OBJECTIVE: To assess whether antibiotic reduces voiding cystourethrogram (VCUG)-associated urinary tract infection (UTI). DESIGN: Open-labelled randomised controlled trial. SETTING: Tertiary paediatric nephrology centre. PATIENTS: 120 children (age 2 months-5 years) undergoing VCUG. INTERVENTIONS: Children were randomised into group A (antibiotic, n=72) or group B (no antibiotic, n=48) in 3:2 ratio...
August 30, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28845468/evolutionary-nephrology
#20
Robert L Chevalier
Progressive kidney disease follows nephron loss, hyperfiltration, and incomplete repair, a process described as "maladaptive." In the past 20 years, a new discipline has emerged that expands research horizons: evolutionary medicine. In contrast to physiologic (homeostatic) adaptation, evolutionary adaptation is the result of reproductive success that reflects natural selection. Evolutionary explanations for physiologically maladaptive responses can emerge from mismatch of the phenotype with environment or evolutionary tradeoffs...
May 2017: KI Reports
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