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Assessment short-term memory

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https://www.readbyqxmd.com/read/28088063/verbal-and-musical-short-term-memory-variety-of-auditory-disorders-after-stroke
#1
Catherine Hirel, Norbert Nighoghossian, Yohana Lévêque, Salem Hannoun, Lesly Fornoni, Sébastien Daligault, Patrick Bouchet, Julien Jung, Barbara Tillmann, Anne Caclin
Auditory cognitive deficits after stroke may concern language and/or music processing, resulting in aphasia and/or amusia. The aim of the present study was to assess the potential deficits of auditory short-term memory for verbal and musical material after stroke and their underlying cerebral correlates with a Voxel-based Lesion Symptom Mapping approach (VLSM). Patients with an ischemic stroke in the right (N=10) or left (N=10) middle cerebral artery territory and matched control participants (N=14) were tested with a detailed neuropsychological assessment including global cognitive functions, music perception and language tasks...
January 11, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28079014/predicting-cognitive-decline-across-four-decades-in-mutation-carriers-and-non-carriers-in-autosomal-dominant-alzheimer-s-disease
#2
Ove Almkvist, Elena Rodriguez-Vieitez, Steinunn Thordardottir, Kaarina Amberla, Karin Axelman, Hans Basun, Anne Kinhult-Ståhlbom, Lena Lilius, Anne Remes, Lars-Olof Wahlund, Matti Viitanen, Lars Lannfelt, Caroline Graff
OBJECTIVES: The aim of this study was to investigate cognitive performance including preclinical and clinical disease course in carriers and non-carriers of autosomal-dominant Alzheimer's disease (adAD) in relation to multiple predictors, that is, linear and non-linear estimates of years to expected clinical onset of disease, years of education and age. METHODS: Participants from five families with early-onset autosomal-dominant mutations (Swedish and Arctic APP, PSEN1 M146V, H163Y, and I143T) included 35 carriers (28 without dementia and 7 with) and 44 non-carriers...
January 12, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28074268/cognitive-deficits-in-patients-with-a-chronic-vestibular-failure
#3
Pauline Popp, Melanie Wulff, Kathrin Finke, Maxine Rühl, Thomas Brandt, Marianne Dieterich
Behavioral studies in rodents and humans have demonstrated deficits of spatial memory and orientation in bilateral vestibular failure (BVF). Our aim was to explore the functional consequences of chronic vestibular failure on different cognitive domains including spatial as well as non-spatial cognitive abilities. Sixteen patients with a unilateral vestibular failure (UVF), 18 patients with a BVF, and 17 healthy controls (HC) participated in the study. To assess the cognitive domains of short-term memory, executive function, processing speed and visuospatial abilities the following tests were used: Theory of Visual Attention (TVA), TAP Alertness and Visual Scanning, the Stroop Color-Word, and the Corsi Block Tapping Test...
January 10, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28073379/tau-passive-immunization-inhibits-not-only-tau-but-also-a%C3%AE-pathology
#4
Chun-Ling Dai, Yunn Chyn Tung, Fei Liu, Cheng-Xin Gong, Khalid Iqbal
BACKGROUND: Accumulation of hyperphosphorylated tau protein is a histopathological hallmark of Alzheimer's disease (AD) and related tauopathies. Currently, there is no effective treatment available for these progressive neurodegenerative diseases. In recent years, tau immunotherapy has shown great potential in animal models. We report the effect of immunization with tau antibodies 43D against tau 6-18 and 77E9 against tau 184-195 on tau and amyloid-β (Aβ) pathologies and cognition in triple-transgenic (3×Tg)-AD mice at mild to moderate stages of the disease...
January 10, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28069458/loganin-enhances-long-term-potentiation-and-recovers-scopolamine-induced-learning-and-memory-impairments
#5
Eun-Sang Hwang, Hyun-Bum Kim, Seok Lee, Min-Ji Kim, Sung-Ok Lee, Seung-Moo Han, Sungho Maeng, Ji-Ho Park
Although the incidence rate of dementia is rapidly growing in the aged population, therapeutic and preventive reagents are still suboptimal. Various model systems are used for the development of such reagents in which scopolamine is one of the favorable pharmacological tools widely applied. Loganin is a major iridoid glycoside obtained from Corni fructus (Cornusofficinaliset Zucc) and demonstrated to have anti-inflammatory, anti-tumor and osteoporosis prevention effects. It has also been found to attenuate Aβ-induced inflammatory reactions and ameliorate memory deficits induced by scopolamine...
January 6, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28069457/quercetin-prevents-chronic-unpredictable-stress-induced-behavioral-dysfunction-in-mice-by-alleviating-hippocampal-oxidative-and-inflammatory-stress
#6
Vineet Mehta, Arun Parashar, Malairaman Udayabanu
It is now evident that chronic stress is associated with anxiety, depression and cognitive dysfunction and very few studies have focused on identifying possible methods to prevent these stress-induced disorders. Previously, we identified abundance of quercetin in Urtica dioica extract, which efficiently attenuated stress related complications. Therefore, current study was designed to investigate the effect of quercetin on chronic unpredicted stress (CUS) induced behavioral dysfunction, oxidative stress and neuroinflammation in the mouse hippocampus...
January 7, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28068110/maternal-scaffolding-in-a-disadvantaged-global-context-the-influence-of-working-memory-and-cognitive-capacities
#7
Jelena Obradović, Ximena A Portilla, Nicole Tirado-Strayer, Saima Siyal, Muneera A Rasheed, Aisha K Yousafzai
The current study focuses on maternal cognitive capacities as determinants of parenting in a highly disadvantaged global context, where children's experiences at home are often the 1st and only opportunity for learning and intellectual growth. In a large sample of 1,291 biological mothers of preschool-aged children in rural Pakistan, we examined the unique association of maternal working memory skills (independent of related cognitive capacities) with cognitively stimulating parenting behaviors. Path analysis revealed that directly assessed working memory, short-term memory, and verbal intelligence independently predicted greater levels of observed maternal scaffolding behaviors...
January 9, 2017: Journal of Family Psychology: JFP
https://www.readbyqxmd.com/read/28067192/effect-of-retrieval-practice-on-short-term-and-long-term-retention-in-hiv-individuals
#8
Gunes Avci, Steven P Woods, Marizela Verduzco, David P Sheppard, James F Sumowski, Nancy D Chiaravalloti, John DeLuca
OBJECTIVES: Episodic memory deficits are both common and impactful among persons infected with HIV; however, we know little about how to improve such deficits in the laboratory or in real life. Retrieval practice, by which retrieval of newly learned material improves subsequent recall more than simple restudy, is a robust memory boosting strategy that is effective in both healthy and clinical populations. In this study, we investigated the benefits of retrieval practice in 52 people living with HIV and 21 seronegatives...
January 9, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28063392/differences-in-the-verbal-fluency-working-memory-and-executive-functions-in-alcoholics-short-term-vs-long-term-abstainers
#9
Katarzyna Nowakowska-Domagała, Karolina Jabłkowska-Górecka, Łukasz Mokros, Jacek Koprowicz, Tadeusz Pietras
The aim of the study was to assess differences in verbal fluency, working memory and executive functions in two subgroups of alcohol-dependent patients, those undergoing short-term abstinence (STA) and those undergoing long-term abstinence (LTA), and to compare the level of cognitive functions in patients after long-term abstinence with healthy subjects. The study group consisted of 106 alcohol-dependent patients (53 immediately after drinking at least 3 days and 53 after at least one-year abstinence). The control group comprised 53 subjects, whose age, sex and education levels matched those of the patients in the experimental group...
December 27, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28063244/single-sided-deafness-affects-language-and-auditory-development-a-case-control-study
#10
Anouk Sangen, Liesbeth Royackers, Christian Desloovere, Jan Wouters, Astrid van Wieringen
OBJECTIVES: To examine auditory, linguistic and cognitive outcomes of children with single sided deafness (SSD). An increasing body of research suggests that children with SSD lag behind with respect to their normal hearing (NH) peers. In the present study we tap into certain developmental skills. DESIGN: Case-control study. PARTICIPANTS: 21 children with SSD between 5 and 15 years of age participated. Per child with SSD two NH control children were matched on age and gender...
January 7, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28057534/altered-fronto-striatal-functions-in-the-gdi1-null-mouse-model-of-x-linked-intellectual-disability
#11
Lorenzo Morè, Basil Künnecke, Latefa Yekhlef, Andreas Bruns, Antonella Marte, Ernesto Fedele, Veronica Bianchi, Stefano Taverna, Silvia Gatti, Patrizia D'Adamo
RAB-GDP dissociation inhibitor 1 (GDI1) loss-of-function mutations are responsible for a form of non-specific X-linked Intellectual Disability (XLID) where the only clinical feature is cognitive impairment. GDI1 patients are impaired in specific aspects of executive functions and conditioned response, which are controlled by fronto-striatal circuitries. Previous molecular and behavioral characterization of the Gdi1-null mouse revealed alterations in the total number/distribution of hippocampal and cortical synaptic vesicles as well as hippocampal short-term synaptic plasticity, and memory deficits...
January 3, 2017: Neuroscience
https://www.readbyqxmd.com/read/28045968/the-bachd-rat-model-of-huntington-disease-shows-signs-of-fronto-striatal-dysfunction-in-two-operant-conditioning-tests-of-short-term-memory
#12
Erik Karl Håkan Clemensson, Laura Emily Clemensson, Olaf Riess, Huu Phuc Nguyen
The BACHD rat is a recently developed transgenic animal model of Huntington disease, a progressive neurodegenerative disorder characterized by extensive loss of striatal neurons. Cognitive impairments are common among patients, and characterization of similar deficits in animal models of the disease is therefore of interest. The present study assessed the BACHD rats' performance in the delayed alternation and the delayed non-matching to position test, two Skinner box-based tests of short-term memory function...
2017: PloS One
https://www.readbyqxmd.com/read/28045787/some-neurocognitive-correlates-of-noise-vocoded-speech-perception-in-children-with-normal-hearing-a-replication-and-extension-of-eisenberg-et-al-2002
#13
Adrienne S Roman, David B Pisoni, William G Kronenberger, Kathleen F Faulkner
OBJECTIVES: Noise-vocoded speech is a valuable research tool for testing experimental hypotheses about the effects of spectral degradation on speech recognition in adults with normal hearing (NH). However, very little research has utilized noise-vocoded speech with children with NH. Earlier studies with children with NH focused primarily on the amount of spectral information needed for speech recognition without assessing the contribution of neurocognitive processes to speech perception and spoken word recognition...
December 27, 2016: Ear and Hearing
https://www.readbyqxmd.com/read/28038797/brain-volume-and-cognitive-function-in-patients-with-revascularized-coronary-artery-disease
#14
Thomas H Ottens, Jeroen Hendrikse, Hendrik M Nathoe, Geert Jan Biessels, Diederik van Dijk
BACKGROUND: The pathogenesis of cognitive dysfunction in patients with CAD remains unclear. CAD is associated with brain atrophy and specific lesions. Detailed knowledge about the association of brain volume measured with MRI, and cognitive function in patients with CAD is lacking. We therefore investigated brain volume and cognitive function in patients with revascularized coronary artery disease (CAD), and controls without CAD. METHODS: Brain MRI scans and cognitive tests from patients with CAD were compared with data from control subjects without CAD...
December 21, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28038406/beta-hydroxy-beta-methylbutyrate-hmb-ameliorates-age-related-deficits-in-water-maze-performance-especially-in-male-rats
#15
Daniel G Kougias, Emily R Hankosky, Joshua M Gulley, Janice M Juraska
Beta-hydroxy-beta-methylbutyrate (HMB) is commonly supplemented to maintain muscle in elderly and clinical populations and has potential as a nootropic. Previously, we have shown that in both male and female rats, long-term HMB supplementation prevents age-related dendritic shrinkage within the medial prefrontal cortex (mPFC) and improves cognitive flexibility and working memory performance that are both age- and sex-specific. In this study, we further explore the cognitive effects by assessing visuospatial learning and memory with the Morris water maze...
December 27, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/28032373/meaningful-memory-in-acute-anorexia-nervosa-patients-comparing-recall-learning-and-recognition-of-semantically-related-and-semantically-unrelated-word-stimuli
#16
Valentin Terhoeven, Ursula Kallen, Katrin Ingenerf, Steffen Aschenbrenner, Matthias Weisbrod, Wolfgang Herzog, Timo Brockmeyer, Hans-Christoph Friederich, Christoph Nikendei
OBJECTIVE: It is unclear whether observed memory impairment in anorexia nervosa (AN) depends on the semantic structure (categorized words) of material to be encoded. We aimed to investigate the processing of semantically related information in AN. METHOD: Memory performance was assessed in a recall, learning, and recognition test in 27 adult women with AN (19 restricting, 8 binge-eating/purging subtype; average disease duration: 9.32 years) and 30 healthy controls using an extended version of the Rey Auditory Verbal Learning Test, applying semantically related and unrelated word stimuli...
December 29, 2016: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28012947/the-gsk-3-inhibitor-vp2-51-produces-antidepressant-effects-associated-with-adult-hippocampal-neurogenesis
#17
Paloma Pérez-Domper, Valle Palomo, Simona Gradari, Carmen Gil, María L de Ceballos, Ana Martínez, Jose Luis Trejo
Glycogen synthase kinase 3 (GSK-3) is a constitutively active kinase that has been implicated in the mechanism of action of mood stabilizers. According to the neurogenic hypothesis of depression, newborn neurons in the adult dentate gyrus are required for the antidepressant effects of certain agents. We demonstrate that administration of the GSK-3 inhibitor VP2.51 (2.5 mg/kg ip, for 3.5 weeks) increases cell proliferation (pH3(+) cells), as well as the short- and long-term survival of newborn neurons (assessed by the 24 h survival of BrdU(+) and DCX(+) neurons), while significantly increasing the commitment of cells to the granule neuron lineage (Prox1 immunoreactivity)...
December 22, 2016: Neuropharmacology
https://www.readbyqxmd.com/read/28011771/improving-protein-disorder-prediction-by-deep-bidirectional-long-short-term-memory-recurrent-neural-networks
#18
Jack Hanson, Yuedong Yang, Kuldip Paliwal, Yaoqi Zhou
MOTIVATION: Capturing long-range interactions between structural but not sequence neighbors of proteins is a long-standing challenging problem in bioinformatics. Recently, long short-term memory (LSTM) networks have significantly improved the accuracy of speech and image classification problems by remembering useful past information in long sequential events. Here, we have implemented deep bidirectional LSTM recurrent neural networks in the problem of protein intrinsic disorder prediction...
December 22, 2016: Bioinformatics
https://www.readbyqxmd.com/read/27996218/association-of-early-physical-activity-time-with-pain-activities-of-daily-living-and-progression-of-vertebral-body-collapse-in-patients-with-vertebral-compression-fractures-an-observational-study-at-single-institution
#19
Hideki Kataoka, Tatsunori Ikemoto, Ayana Yoshimura, Mihoko Shibuya, Kyo Goto, Jyunichirou Yamashita, Kaoru Morita, Jyunya Sakamoto, Jiro Nakano, Minoru Okita
BACKGROUND: Physical activity can reduce pain and improve the ability to perform daily activities in patients with acute low back pain (LBP) due to various non-specific causes. The association between physical activity during the early phase of acute vertebral compression fractures (VCFs) and rehabilitation outcomes is unknown. AIM: To investigate the effects of early physical activity time (EPAT) on pain following acute VCFs, recovery of the ability to perform activities of daily living (ADLs), and progression of fractured vertebral body collapse...
December 19, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27995604/exercise-therapy-for-chronic-fatigue-syndrome
#20
REVIEW
Lillebeth Larun, Kjetil G Brurberg, Jan Odgaard-Jensen, Jonathan R Price
BACKGROUND: Chronic fatigue syndrome (CFS) is characterised by persistent, medically unexplained fatigue, as well as symptoms such as musculoskeletal pain, sleep disturbance, headaches and impaired concentration and short-term memory. CFS presents as a common, debilitating and serious health problem. Treatment may include physical interventions, such as exercise therapy, which was last reviewed in 2004. OBJECTIVES: The objective of this review was to determine the effects of exercise therapy (ET) for patients with CFS as compared with any other intervention or control...
December 20, 2016: Cochrane Database of Systematic Reviews
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