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Assessment psychosis

M Canal-Rivero, J D López-Moríñigo, E Setién-Suero, M Ruiz-Veguilla, J L Ayuso-Mateos, R Ayesa-Arriola, B Crespo-Facorro
BACKGROUND: Suicide has been recognised as one of the major causes of premature death in psychosis. However, predicting suicidal behaviour (SB) is still challenging in the clinical setting and the association of neurocognition with SB in psychosis remains poorly understood. This study aimed to investigate the role of neurocognitive performance as predictor of SB. Also, we sought to explore differences in the evolution of clinical and neurocognitive functioning between participants with/without history of suicide attempts (SA) over follow-up period...
June 18, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
Robin Martin, Marie Rose Moro, Laelia Benoit
AIM: A background of migration is an established risk factor for psychosis. At the same time, over the last 25 years, many countries have developed specialized services for the assessment and care of people with early psychosis. Evaluation of these services often focuses on the duration of untreated psychosis (DUP). METHODS: We conducted a systematic review with an electronic search of key words in 3 databases to determine the extent to which studies measuring DUP consider transcultural variables, including migration status, national origin, ethnicity and language...
June 21, 2018: Early Intervention in Psychiatry
Emma M Parrish, Nancy S Kim, Kristen A Woodberry, Michelle Friedman-Yakoobian
AIM: Schizophrenia is a highly stigmatized disorder. Identification of youth at high risk for psychosis has the potential for improved outcomes. However, identifying youth at risk could subject them to increased public stigma. Using an experimental vignette design, this study examined relative levels of public stigma elicited by the labels "schizophrenia," "clinical high risk (CHR)," "attenuated psychotic symptoms syndrome (APSS)," a label implying normative adolescent development ("a bad breakup"), and a no-label control condition...
June 21, 2018: Early Intervention in Psychiatry
Taciana C C Ragazzi, Rosana Shuhama, Paulo R Menezes, Cristina M Del-Ben
AIM: Epidemiological data have provided evidence that psychotic-like experiences (PLEs) can occur in the general population, not necessarily accompanied by the impairment and suffering observed in formal psychiatric diagnoses. According to the psychosis continuum hypothesis, PLEs would be subject to the same risk factors as frank psychosis. The aim of this review was to summarize observational studies that evaluated cannabis use as a risk factor for PLEs as determined by the Community Assessment of Psychic Experiences in non-clinical samples...
June 21, 2018: Early Intervention in Psychiatry
Nicoline Hemager, Kerstin J Plessen, Anne Thorup, Camilla Christiani, Ditte Ellersgaard, Katrine Søborg Spang, Birgitte Klee Burton, Maja Gregersen, Anne Søndergaard, Aja Neergaard Greve, Ditte Lou Gantriis, Gry Poulsen, Larry J Seidman, Ole Mors, Merete Nordentoft, Jens Richardt Møllegaard Jepsen
Importance: Children at familial high risk of schizophrenia spectrum disorders (FHR-SZ) or bipolar disorder (FHR-BP) exhibit neurocognitive impairments. Large studies of neurocognition in young children at familial high risk at the same age are important to differentiate the pathophysiology and developmental trajectory of these 2 groups. Objective: To characterize neurocognitive functions in 7-year-old children with FHR-SZ or FHR-BP and a control population. Design, Setting, and Participants: This multisite population-based cohort study collected data from January 1, 2013, to January 31, 2016, in the first wave of the Danish High Risk and Resilience Study VIA 7 at 2 university hospital research sites in Copenhagen and Aarhus using Danish registries...
June 20, 2018: JAMA Psychiatry
Mark van der Gaag, Liesbeth Eurelings-Bontekoe, Helga Ising, David van den Berg
AIMS: Childhood adversities combined with unsafe parenting may disturb personality development. This study investigated whether psychotic personality organization as defined by Kernberg and assessed with de Dutch Short Form of the MMPI (DSFM) is more prevalent in ultrahigh risk (UHR) for psychosis compared with non-psychotic psychiatric control patients (NPPC). METHODS: A total of 73 UHR and 119 NPPC patients were assessed with the DSFM and the Comprehensive Assessment of at Risk Mental States (CAARMS)...
June 19, 2018: Early Intervention in Psychiatry
Asiel Yair Adan Sanchez, Elizabeth McMillan, Amit Bhaduri, Nancy Pehlivan, Katherine Monson, Paul Badcock, Katherine Thompson, Eoin Killackey, Andrew Chanen, Brian O'Donoghue
AIM: This study aimed to determine the prevalence of high-risk sexual behaviours, sequelae and associated factors in young people attending a youth mental health service. METHODS: The study design was a cross-sectional survey of 103 young people aged between 15-25 years carried out across four specialist mental health clinics. A questionnaire on the sexual health of secondary level students was adapted for this study. Mental health symptomatology was assessed through the Brief Psychiatric Rating Scale (BPRS)...
June 19, 2018: Early Intervention in Psychiatry
Lasse M Giil, Dag Aarsland, Kristoffer Hellton, Anders Lund, Harald Heidecke, Kai Schulze-Forster, Gabriela Riemekasten, Audun Osland Vik-Mo, Einar K Kristoffersen, Christian A Vedeler, Jan Erik Nordrehaug
BACKGROUND: Endogenous antibodies to signaling molecules and receptors (Abs) are associated with Alzheimer's disease (AD). OBJECTIVES: To investigate the association of 33 Abs to dopaminergic, serotoninergic, muscarinic, adrenergic, vascular, and immune receptors with cognitive, neuropsychiatric, and mortality outcomes. METHODS: Ninety-one patients with mild AD were followed annually for 5 years with the Mini-Mental State Examination (MMSE) and the Neuropsychiatric Inventory (NPI; composite outcomes: "psychosis" (item 1 + 2), "mood" (item 4 + 5 + 7), and "agitation" (item 3 + 8 + 9))...
June 9, 2018: Journal of Alzheimer's Disease: JAD
R David Hayward, Mary M Fessler, Joseph Buck, Richard D Fessler
INTRODUCTION: Studies have shown an increased risk of traumatic brain injury (TBI) for individuals who suffer an initial TBI. The current study hypothesized that individuals with recurrent neurotrauma would originate from populations considered 'vulnerable', i.e. low income and/or with psychiatric comorbidities. METHODS: Data from the Michigan State Inpatient Database from 2006 to 2014 for the Detroit metropolitan area enlisted a study population of 50 744 patients with neurotrauma...
June 18, 2018: Brain Injury: [BI]
Benjamin Walter Jack Spencer, Tania Gergel, Matthew Hotopf, Gareth S Owen
BACKGROUND: Consent to research with decision-making capacity for research (DMC-R) is normally a requirement for study participation. Although the symptoms of schizophrenia and related psychoses are known to affect decision-making capacity for treatment (DMC-T), we know little about their effect on DMC-R.AimsWe aimed to determine if DMC-R differs from DMC-T in proportion and associated symptoms in an in-patient sample of people with schizophrenia and related psychoses. METHOD: Cross-sectional study of psychiatric in-patients admitted for assessment and/or treatment of schizophrenia and related psychoses...
June 18, 2018: British Journal of Psychiatry: the Journal of Mental Science
Raeana E Newberry, Derek J Dean, Madison D Sayyah, Vijay A Mittal
BACKGROUND: Exercise has increasingly been proposed as a healthful intervention prior to and after the onset of psychosis. There is some evidence to suggest that youth at clinical high risk (CHR) for psychosis are less physically active and report more barriers to engaging in exercise; however, there has been relatively limited empirical work documenting this phenomenon, and to date, relationships between physical activity, barriers, and clinical phenomenology have been unclear. METHODS: CHR (N = 51) and healthy control (N = 37) participants completed a structured clinical interview assessing attenuated psychotic symptoms and substance use, and an exercise survey that assessed current exercise practices, perceived physical fitness, and barriers related to engaging in exercise...
June 13, 2018: Schizophrenia Research
Frances Dark, Meredith Harris, Victoria Gore-Jones, Ellie Newman, Harvey Whiteford
BACKGROUND: To evaluate the planned implementation of group based Cognitive Remediation therapy (CR) and Social Cognitive Interaction Training (SCIT) into routine psychosis care in a mental health service in Australia. METHOD: The study was conducted over 3 years in a mental health service in a metropolitan city in Australia. Participants were 22 program facilitators and 128 patients attending the programs. Implementation outcomes were assessed using administrative data, staff surveys and program audits...
June 15, 2018: BMC Health Services Research
Thomas Vaessen, Zuzana Kasanova, Dennis Hernaus, Johan Lataster, Dina Collip, Martine van Nierop, Inez Myin-Germeys
OBJECTIVE: Results from experimental studies suggest that psychosis and psychosis liability are associated with increased cortisol levels and blunted cortisol reactivity, and that use of antipsychotics may reduce these aberrations. Here, we report on overall cortisol, diurnal slope, and cortisol stress reactivity in everyday life in psychosis and psychosis liability using the experience sampling method (ESM). METHODS: Our sample consisted of individuals diagnosed with psychotic disorder currently on (MPD; n = 53) or off antipsychotic medication (NMPD; n = 20), first-degree relatives of psychotic patients (REL; n = 47), and healthy volunteers (HV; n = 67)...
June 7, 2018: Psychoneuroendocrinology
Christine Mohn, Anna-Karin Olsson, Lars Helldin
Dysfunctional affectivity is common in schizophrenia spectrum disorders (SSD), and may influence quality of life, illness progression and treatment effects. This study describes Positive (PA) and Negative (NA) affect and their relationship to demographic and clinical variables in 135 individuals with SSD. Affect dimensions were assessed by the Positive and Negative Affect Schedule (PANAS). Stepwise regression analyses with affects as dependent variables and demographic and clinical factors as independent variables were performed...
June 2, 2018: Psychiatry Research
Ann Faerden, Siv Hege Lyngstad, Carmen Simonsen, Petter Andreas Ringen, Oleg Papsuev, Ingrid Dieset, Ole A Andreassen, Ingrid Agartz, Stephen R Marder, Ingrid Melle
Negative symptoms have traditionally been assessed based on clinicians' observations. The subjective experience of negative symptoms in people with psychosis may bring new insight. The Apathy Evaluation Scale (AES) is commonly used to study apathy in psychosis and has corresponding self-rated (AES-S) and clinician-rated (AES-C) versions. The aim of the present study was to determine the validity and reliability of the AES-S by investigating its concordance with the AES-C. Eighty-four first-episode (FEP) patients completed the shortened 12-item AES-S and AES-C at baseline (T1) and 12 months (T2)...
May 31, 2018: Psychiatry Research
Hyoun S Kim, Briana D Cassetta, David C Hodgins, Daniel S McGrath, Lianne M Tomfohr-Madsen, Hermano Tavares
OBJECTIVE: While it has been shown that disordered gamblers with psychosis are at increased risk for comorbid psychopathology, it is unclear whether this dual-diagnosis population is also at greater risk of problematic engagement with comorbid addictive behaviors. METHODS: We tested for association between disordered gambling with psychosis and comorbid addictive behaviors in a sample of 349 treatment-seeking disordered gamblers. RESULTS: Twenty-five (7...
June 11, 2018: Revista Brasileira de Psiquiatria
Shengyu Zhang, Qiang Hu, Tao Tang, Chao Liu, Chengchong Li, Yin-Yin Zang, Wei-Xiong Cai
BACKGROUND Using regional homogeneity (ReHo) blood oxygen level-dependent functional MR (BOLD-fMRI), we investigated the structural and functional alterations of brain regions among patients with methamphetamine-associated psychosis (MAP). MATERIAL AND METHODS This retrospective study included 17 MAP patients, 16 schizophrenia (SCZ) patients, and 18 healthy controls. Informed consent was obtained from all patients before the clinical assessment, the severity of clinical symptoms was evaluated prior to the fMRI scanning, and then images were acquired and preprocessed after each participant received 6-min fRMI scanning...
June 13, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Kiyokazu Atake, Tomoyuki Nakamura, Nobuhisa Ueda, Hikaru Hori, Asuka Katsuki, Reiji Yoshimura
Background: Cognitive impairment in schizophrenia can result in considerable difficulty in performing functions of daily life or social rehabilitation. Cognitive impairment in schizophrenia is related to various factors, such as the psychotic severity, aging, medication, and brain-derived neurotrophic factor (BDNF). To date, however, no studies investigating the impact of these factors on cognitive functioning in chronic schizophrenia patients have been performed. Objective: The aim of this study is to identify those factors that influence the cognitive functioning in patients with chronic schizophrenia...
2018: Frontiers in Psychiatry
C Harvey, J Lewis, J Farhall
AIMS: Clinical Practice Guidelines (CPGs) recommend evidence-based psychosocial interventions (EBPIs) to improve consumer recovery; however, availability appears limited. We describe receipt of six EBPIs, reported by people with psychoses, and associations with service and consumer characteristics, including indicators of need (eligibility) and benefit (suitability). METHODS: Participants in the 2010 Australian national survey of psychosis (n = 1825) were interviewed to assess demographic, functional, mental and physical health characteristics and service use in the previous year...
June 12, 2018: Epidemiology and Psychiatric Sciences
Mhairi McDonald, Eleni Christoforidou, Nicola Van Rijsbergen, Ruchika Gajwani, Joachim Gross, Andrew I Gumley, Stephen M Lawrie, Matthias Schwannauer, Frauke Schultze-Lutter, Peter J Uhlhaas
Introduction: Identification of participants at clinical high-risk (CHR) for the development of psychosis is an important objective of current preventive efforts in mental health research. However, the utility of using web-based screening approaches to detect CHR participants at the population level has not been investigated. Methods: We tested a web-based screening approach to identify CHR individuals. Potential participants were invited to a website via e-mail invitations, flyers, and invitation letters involving both the general population and mental health services...
June 8, 2018: Schizophrenia Bulletin
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