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Assessment psychosis

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https://www.readbyqxmd.com/read/29241089/association-of-psychosis-with-antiphospholipid-antibody-syndrome-a-systematic-review-of-clinical-studies
#1
Asma Hallab, Sadiq Naveed, Ahmed Altibi, Mariam Abdelkhalek, Huyen Thi Ngo, Thao Phuong Le, Kenji Hirayama, Nguyen Tien Huy
OBJECTIVE: In this systematic review, we reviewed the association between Antiphospholipid antibody syndrome (APS) and psychosis and focused on the prevalence, clinical presentation, immunologic and neurological workup, treatment options, and clinical outcomes. METHODOLOGY: We performed this systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)'s guidelines. We searched eight databases for potential articles and manually searched references and relevant articles of included studies...
November 16, 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29239292/ethnic-density-effects-for-adult-mental-health-systematic-review-and-meta-analysis-of-international-studies
#2
Laia Bécares, Michael E Dewey, Jayati Das-Munshi
BACKGROUND: Despite increased ethnic diversity in more economically developed countries it is unclear whether residential concentration of ethnic minority people (ethnic density) is detrimental or protective for mental health. This is the first systematic review and meta-analysis covering the international literature, assessing ethnic density associations with mental health outcomes. METHODS: We systematically searched Medline, PsychINFO, Sociological Abstracts, Web of Science from inception to 31 March 2016...
December 14, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29235890/low-density-lipoprotein-cholesterol-and-suicidal-behaviour-in-a-large-sample-of-first-episode-psychosis-patients
#3
Rosa Ayesa-Arriola, Manuel Canal Rivero, Manuel Delgado-Alvarado, Esther Setién-Suero, Jana González-Gómez, Javier Labad, Anthony S David, Benedicto Crespo-Facorro
OBJECTIVES: Our aims were to confirm the relationship between lipid and lipoprotein concentrations and suicidal behaviour in first episode psychosis (FEP) patients. METHODS: Suicidal behaviour was explored in a large FEP sample (N = 383). Baseline lipid profile was compared between those who attempted or completed suicide and those who not presented suicidal behaviour. RESULTS: Low-density lipoprotein cholesterol (LDL-c) (OR = 0.99, 95% CI= 0...
December 13, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/29235251/the-score-distribution-and-factor-structure-of-the-community-assessment-of-psychic-experiences-positive-scale-cape-p15-in-a-canadian-sample
#4
Mashal K Haque, Jill A Jacobson, Christopher R Bowie, Kevin G Munhall
AIM: Psychotic-like experiences (PLEs) share several risk factors with psychotic disorders and confer greater risk of developing a psychotic disorder. Thus, individuals with PLEs not only comprise a valuable population in which to study the aetiology and premorbid changes associated with psychosis, but also represent a high-risk population that could benefit from clinical monitoring or early intervention efforts. METHOD: We examined the score distribution and factor structure of the current 15-item Community Assessment of Psychic Experiences-Positive Scale (CAPE-P15) in a Canadian sample...
December 13, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29235240/gender-differences-in-first-self-perceived-signs-and-symptoms-in-patients-with-an-at-risk-mental-state-and-first-episode-psychosis
#5
Ulrike Heitz, Erich Studerus, Stephanie Menghini-Müller, Martina Papmeyer, Laura Egloff, Sarah Ittig, Astrid Navarra, Christina Andreou, Anita Riecher-Rössler
AIM: Gender differences in the current symptomatology of patients with psychotic disorders have previously been described in the literature. However, it has not yet been investigated whether gender differences exist in the very first self-perceived signs or symptoms of illness onset. The aim of this study was to investigate this aspect in at-risk mental state (ARMS) and first-episode psychosis (FEP) patients. METHODS: ARMS and FEP were recruited via the early detection of psychosis (FePsy) clinic Basel, Switzerland...
December 13, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29233195/intact-striatal-dopaminergic-modulation-of-reward-learning-and-daily-life-reward-oriented-behavior-in-first-degree-relatives-of-individuals-with-psychotic-disorder
#6
Zuzana Kasanova, Jenny Ceccarini, Michael J Frank, Thérèse van Amelsvoort, Jan Booij, Esther van Duin, Henrietta Steinhart, Thomas Vaessen, Alexander Heinzel, Felix Mottaghy, Inez Myin-Germeys
BACKGROUND: Abnormalities in reward learning in psychotic disorders have been proposed to be linked to dysregulated subcortical dopaminergic (DA) neurotransmission, which in turn is a suspected mechanism for predisposition to psychosis. We therefore explored the striatal dopaminergic modulation of reward processing and its behavioral correlates in individuals at familial risk for psychosis. METHODS: We performed a DA D2/3 receptor [18F]fallypride positron emission tomography scan during a probabilistic reinforcement learning task in 16 healthy first-degree relatives of patients with psychosis and 16 healthy volunteers, followed by a 6-day ecological momentary assessment study capturing reward-oriented behavior in the everyday life...
December 13, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29232966/sex-differences-in-the-relationship-between-prolactin-levels-and-impaired-processing-speed-in-early-psychosis
#7
Itziar Montalvo, Roser Nadal, Antonio Armario, Alfonso Gutiérrez-Zotes, Marta Creus, Ángel Cabezas, Montse Solé, Maria José Algora, Vanessa Sánchez-Gistau, Elisabet Vilella, Javier Labad
INTRODUCTION: Hyperprolactinaemia is commonly observed in people with psychotic disorders due to D2 receptor blockade by antipsychotic drugs, although it may also exist in drug-naïve patients with first-episode psychosis. Recent studies suggest that hyperprolactinaemia may have a negative impact on cognitive function in people with early psychosis. We aimed to explore whether there are sex differences in the association between prolactin levels and cognitive performance in early psychosis patients...
December 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29230968/attenuated-first-rank-symptoms-and-conversion-to-psychosis-in-a-clinical-high-risk-cohort
#8
Francesca M Crump, Leigh Arndt, Margaux Grivel, Guillermo Horga, Cheryl M Corcoran, Gary Brucato, Ragy R Girgis
AIM: We sought to examine attenuated first-rank symptoms (FRS) and subcomponents of the Unusual Thought Content (P.1.) section of the Structured Interview for Psychosis-Risk Syndromes (SIPS) to investigate the robust relationship between total P.1. and conversion. We hypothesized that attenuated FRS would drive the association and, additionally, be most predictive of a schizophrenia diagnosis. METHOD: We assessed 189 clinical high-risk participants. Two independent raters separately scored attenuated FRS and each subcomponent of P...
December 12, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29228174/cardiovascular-risk-in-early-psychosis-relationship-with-inflammation-and-clinical-features-6-months-after-diagnosis
#9
Molero M F Barcones, K S MacDowell, B García Bueno, M Bioque, L Gutiérrez-Galve, A González Pinto, M J Parellada, J Bobes, M Bernardo, A Lobo, J C Leza
Background: We aimed to investigate the state of cardiovascular risk/protection factors in early psychosis patients. Methods: 119 subjects were recruited during the first year after their first episode of psychosis (FEP). 85 of these subjects were followed during the next 6 months. Cardiovascular risk/protection factors were measured in plasma and co-variated by sociodemographic/clinical characteristics. Multiple linear regression models detected the change of each biological marker from baseline to follow-up in relation to clinical scales, antipsychotic medication and pro/anti-inflammatory mediators...
December 8, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29227894/substance-induced-psychotic-symptoms-in-borderline-personality-disorder-among-substance-use-disorder-samples-in-spain
#10
Carmen Barral, Laia Rodríguez-Cintas, Lara Grau-López, Constanza Daigre, Elena Ros-Cucurull, Natalia Calvo, Marc Ferrer, Carlos Roncero
Substance-induced psychosis (SIP) is frequent in substance use disorder patients. However, little is known about the presence of SIP in Borderline Personality Disorder (BPD) and what the risk factors for the development of SIP in this population would be. A sample of 91 BPD drug-dependent patients attending an outpatient substance use disorder unit was evaluated. Comorbidity with Axis I and II was assessed using SCID-I and SCID-II. Psychoactive drug related variables were registered as well as the presence of the ninth criterion of DSM-IV-TR as a code of psychotic symptoms...
December 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29226809/vitamin-d-supplementation-in-chronic-schizophrenia-patients-treated-with-clozapine-a-randomized-double-blind-placebo-controlled-clinical-trial
#11
Amir Krivoy, Roy Onn, Yael Vilner, Eldar Hochman, Shira Weizman, Amir Paz, Shmuel Hess, Roi Sagy, Shiri Kimhi-Nesher, Ehud Kalter, Tal Friedman, Zvi Friedman, Gil Bormant, Sharon Trommer, Avi Valevski, Abraham Weizman
BACKGROUND: While accumulating evidence suggests that vitamin D deficiency may be involved in the risk to develop schizophrenia and its outcome, there are no studies on vitamin D supplementation in this context. We sought to assess the effect of vitamin D supplementation on psychiatric, cognitive and metabolic parameters in chronic clozapine-treated schizophrenia patients. METHODS: This eight-week, randomized, double-blind, placebo-controlled clinical trial, recruited schizophrenia patients who had been maintained on clozapine treatment for at least 18weeks and had low levels of vitamin D (<75nmol/l) and total PANSS scores >70 (to ascertain the presence of residual symptoms)...
December 2, 2017: EBioMedicine
https://www.readbyqxmd.com/read/29224570/mapping-the-evidence-on-pharmacological-interventions-for-non-affective-psychosis-in-humanitarian-non-specialised-settings-a-unhcr-clinical-guidance
#12
Giovanni Ostuzzi, Corrado Barbui, Charlotte Hanlon, Sudipto Chatterjee, Julian Eaton, Lynne Jones, Derrick Silove, Peter Ventevogel
BACKGROUND: Populations exposed to humanitarian emergencies are particularly vulnerable to mental health problems, including new onset, relapse and deterioration of psychotic disorders. Inadequate care for this group may lead to human rights abuses and even premature death. The WHO Mental Health Gap Action Programme Intervention Guide (mhGAP-IG), and its adaptation for humanitarian settings (mhGAP-HIG), provides guidance for management of mental health conditions by non-specialised healthcare professionals...
December 11, 2017: BMC Medicine
https://www.readbyqxmd.com/read/29224181/social-cognition-and-aggression-in-methamphetamine-dependence-with-and-without-a-history-of-psychosis
#13
Anne Uhlmann, Jonathan C Ipser, Don Wilson, Dan J Stein
In substance use and psychotic disorders, socially problematic behaviours, such as high aggression may, in part, be explained by deficits in social cognition skills, like the detection of emotions or intentions in others. The aim of this study was to assess the magnitude of social cognition impairment and its association with aggression in individuals with methamphetamine (MA) dependence, methamphetamine-associated psychosis (MAP), and healthy controls (CTRL). A total of 20 MAP participants, 21 MA-dependent participants without psychosis, and 21 CTRL participants performed a facial morphing emotion recognition task (ERT) across four basic emotions (anger, fear, happiness and sadness) and the reading the mind in the eyes task (RMET), and completed the aggression questionnaire...
December 9, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29221470/potential-diagnostic-markers-of-olanzapine-efficiency-for-acute-psychosis-a-focus-on-peripheral-biogenic-amines
#14
A E Taraskina, R F Nasyrova, A M Zabotina, D N Sosin, К А Sosina, E E Ershov, M N Grunina, E M Krupitsky
BACKGROUND: Biomarkers are now widely used in many fields of medicine, and the identification of biomarkers that predict antipsychotic efficacy and adverse reactions is a growing area of psychiatric research. Monoamine molecules of the peripheral bloodstream are possible prospective biomarkers based on a growing body of evidence indicating that they may reflect specific changes in neurotransmitters in the brain. The aim of this study was to detect peripheral biogenic amine indicators of patients with acute psychosis and to test the correlations between the biological measures studied and the psychopathological status of the patients...
December 8, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29220783/a-study-to-compare-the-differences-between-genders-in-psychiatric-comorbidities-in-individuals-with-psychoses
#15
Praveen Das, Priya Sreedaran, Ashok Mv
BACKGROUND: Psychiatric comorbidities worsen the outcome and increase severity of suffering in psychotic disorders. Gender differences have also been found to impact the severity and outcome in psychoses. In this background, this study attempted to compare psychiatric comorbidity between genders. AIMS AND OBJECTIVES: The aim was to compare psychiatric co-morbidity between men and women with psychotic disorders. METHODOLOGY: A descriptive cross sectional study design was used...
November 29, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29219171/benzodiazepines-for-psychosis-induced-aggression-or-agitation
#16
REVIEW
Hadar Zaman, Stephanie J Sampson, Alison Ls Beck, Tarang Sharma, Fiona J Clay, Styliani Spyridi, Sai Zhao, Donna Gillies
BACKGROUND: Acute psychotic illness, especially when associated with agitated or violent behaviour, can require urgent pharmacological tranquillisation or sedation. In several countries, clinicians often use benzodiazepines (either alone or in combination with antipsychotics) for this outcome. OBJECTIVES: To examine whether benzodiazepines, alone or in combination with other pharmacological agents, is an effective treatment for psychosis-induced aggression or agitation when compared with placebo, other pharmacological agents (alone or in combination) or non-pharmacological approaches...
December 8, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29218852/psychotic-conversion-of-individuals-at-ultra-high-risk-for-psychosis-the-potential-roles-of-schizotypy-and-basic-symptoms
#17
Minji Bang, Jin Young Park, Kyung Ran Kim, Su Young Lee, Yun Young Song, Jee In Kang, Eun Lee, Suk Kyoon An
AIM: To improve strategies for the early identification of individuals at a heightened risk for the development of psychosis, we investigated the relationships and interactions between 3 psychosis-proneness dimensions for the development of schizophrenia spectrum psychosis: schizotypy, basic symptoms and the ultra-high risk (UHR) criteria. METHODS: Seventy-seven UHR individuals and 79 healthy controls were assessed for schizotypy and basic symptoms using self-report questionnaires at baseline...
December 8, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29215397/keratoconus-and-personality-a-review
#18
Mark J Mannis, Jennifer J Ling, Ralph Kyrillos, Melissa Barnett
PURPOSE: To assess the existing literature on the subject of keratoconus and personality and to propose a theory that might account for the perceived personality changes associated with this condition. METHODS: A literature search was conducted in the PubMed database using the term "keratoconus" in combination with keywords such as personality, psychiatry, psychology, anxiety, depression, or psychosis. A total of 15 articles pertaining to personality and psychiatric disorders in keratoconus were retained and reviewed...
December 5, 2017: Cornea
https://www.readbyqxmd.com/read/29215319/examining-the-potential-preventative-effects-of-minocycline-prescribed-for-acne-on-the-incidence-of-severe-mental-illnesses-a-historical-cohort-study
#19
Maria Herrero-Zazo, Ruth Brauer, Fiona Gaughran, Louise M Howard, David Taylor, David J Barlow
BACKGROUND: Animal studies suggest that the antibiotic and microglial activation inhibitor, minocycline, is likely to have a protective effect against the emergence of psychosis but evidence from human studies is lacking. The aim of this study is to examine the effects of exposure to minocycline during adolescence on the later incidence of severe mental illness (SMI). METHODS: A historical cohort study using electronic primary care data was conducted to assess the association between exposure to minocycline during adolescence and incidence of SMI...
December 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29211039/association-of-social-support-and-medication-adherence-in-chinese-patients-with-type-2-diabetes-mellitus
#20
Linni Gu, Shaomin Wu, Shuliang Zhao, Huixuan Zhou, Shengfa Zhang, Min Gao, Zhiyong Qu, Weijun Zhang, Donghua Tian
The prevalence of diabetes is steadily increasing in China. When diabetes is uncontrolled, it generates dire consequences for health and well-being. Numerous studies have shown that health outcomes were associated with social support and medication adherence. Previous study confirmed that social support was associated with medication adherence in patients with heart failure, HIV diseases, and first-episode psychosis. However, the relationship between social support and medication adherence in patients with type 2 diabetes mellitus (T2DM) is remains unclear...
December 6, 2017: International Journal of Environmental Research and Public Health
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