keyword
MENU ▼
Read by QxMD icon Read
search

Nailfold capillary

keyword
https://www.readbyqxmd.com/read/29151520/dropped-head-syndrome-and-the-presence-of-rimmed-vacuoles-in-a-muscle-biopsy-in-scleroderma-polymyositis-overlap-syndrome-associated-with-anti-ku-antibody
#1
Yoshida Takeshi, Yoshida Mai, Mitsuyo Kinjo, Jonosono Manabu, Higuchi Itsuro
A 66-year-old woman with a history of interstitial lung disease presented with a 3-month history of dropped head syndrome (DHS), followed by camptocormia and extremity weakness. A clinical examination revealed Raynaud phenomenon, arthralgia, distal skin sclerosis, and microbleeds in the nailfold capillaries. An anti-Ku antibody test was positive. A muscle biopsy revealed inflammatory myopathy with rimmed vacuoles (RVs). The diagnosis of scleroderma-polymyositis (SSc-PM) overlap syndrome was made. RVs on a muscle biopsy in a patient with inflammatory myositis involving axial muscles may be seen either in inclusion body myositis or SSc-PM overlap syndrome...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29068146/chronic-inflammation-predicts-long-term-mortality-in-patients-with-raynaud-s-phenomenon
#2
M Mueller, M E Gschwandtner, J Gamper, G-A Giurgea, H P Kiener, T Perkmann, R Koppensteiner, O Schlager
BACKGROUND: Subclinical chronic inflammation could be the driving force behind the recently revealed association between abnormal nailfold capillaries as well as autoantibodies and long-term mortality in patients with incipient Raynaud's phenomenon. Whether laboratory markers that reflect a chronic inflammatory process are directly related to mortality in Raynaud's phenomenon is not known. METHODS: In total, 2958 patients with incipient Raynaud's phenomenon without previously known connective tissue disease (CTD) were enrolled...
October 25, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29037322/improvement-of-nailfold-capillary-microangiopathy-after-immunosuppressant-therapy-in-a-child-with-clinically-amyopathic-juvenile-dermatomyositis
#3
Lúcia Maria Arruda Campos, Adriana M E Sallum, Cintia Z Camargo, Luís Eduardo C Andrade, Cristiane Kayser
No abstract text is available yet for this article.
September 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/29018976/capillary-loss-on-nailfold-capillary-microscopy-is-associated-with-mortality-in-systemic-sclerosis
#4
Thais Rohde Pavan, Markus Bredemeier, Vanessa Hax, Karina Gatz Capobianco, Rafael da Silva Mendonça Chakr, Ricardo Machado Xavier
The objective of this study is to test the association of the severity of nailfold capillaroscopy (NFC) abnormalities with mortality in systemic sclerosis (SSc). One hundred and seventy SSc patients underwent an extensive evaluation (including high-resolution computed tomography, pulmonary function tests, and Doppler echocardiography) at baseline following a standard protocol. Capillary loss on NFC was evaluated using the avascular score (AS, ranging from 0 to 3), and the mean number of ectasias, megacapillaries, and hemorrhages per finger was also recorded...
October 10, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28957564/reproducibility-of-the-scleroderma-pattern-assessed-by-wide-field-capillaroscopy-in-subjects-suffering-from-raynaud-s-phenomenon
#5
MULTICENTER STUDY
Carine Boulon, Sophie Blaise, Isabelle Lazareth, Claire Le Hello, Marc-Antoine Pistorius, Bernard Imbert, Marion Mangin, Pierre Sintes, Patricia Senet, Joëlle Decamps-Le Chevoir, Laurent Tribout, Patrick Carpentier, Joël Constans
Objectives: The aim of this work was to study inter- and intra-observer agreement for the diagnosis of scleroderma pattern by wide-field capillaroscopy. Methods: Images were taken from 50 patients known to have SSc and 50 controls consulting for RP who did not have SSc. These images were rated simultaneously by 11 experienced vascular medicine physicians as scleroderma pattern or not. Two weeks later, 7 of the 11 observers again rated the same images. Results: Inter-observer agreement was almost perfect between the 11 observers (κ 0...
October 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28898558/combination-of-capillaroscopic-and-ultrasonographic-evaluations-in-systemic-sclerosis-results-of-a-cross-sectional-study
#6
Alain Lescoat, Guillaume Coiffier, Marine de Carlan, Catherine Droitcourt, Alice Ballerie, Cazalets Claire, Aleth Perdriger, Jégo Patrick
OBJECTIVES: To compare microvascular damages on nailfold capillaroscopy (NC) with macrovascular manifestations evaluated by hand power doppler ultrasonography (PDUS) in Systemic Sclerosis (SSc) patients, and to assess the associations of these damages with the main digital manifestations of the disease: digital ulcers (DU), acro-osteolysis and Calcinosis. METHODS: NC, hand X-Rays and PDUS were systematically performed in 64 unselected SSc patients. PDUS evaluation with assessment of ulnar artery occlusion (UAO) and finger pulp blood flow (FPBF) was performed blinded for the results of X-Rays and NC...
September 12, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28805016/microvascular-abnormalities-assessed-by-nailfold-capillaroscopy-in-juvenile-dermatomyositis-after-medium-to-long-term-follow-up
#7
Zoltan Barth, Birgit N Witczak, Berit Flatø, Akos Koller, Ivar Sjaastad, Helga Sanner
OBJECTIVE: In juvenile dermatomyositis (JDM), microvascular abnormalities measured by nailfold capillaroscopy (NFC) are common early in disease course. We aimed to compare the presence of NFC abnormalities in patients with medium- to longstanding JDM with that of controls, and to explore associations between NFC abnormalities and disease activity and other disease characteristics. METHODS: Fifty-eight JDM patients clinically examined median 16.8 (2-38) years after disease onset were compared with matched controls...
August 13, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28745214/nailfold-capillaroscopy-of-fingers-and-toes-variations-of-normal
#8
Sevdalina Lambova, Ulf Müller-Ladner
INTRODUCTION: Nailfold capillaroscopy is the only method for morphological assessment of nutritive capillaries. The literature data about capillaroscopic findings of toes in healthy individuals are scarce. THE AIM OF THE STUDY: To evaluate and compare the capillaroscopic findings of fingers and toes in healthy subjects. MATERIALS AND METHODS: 22 healthy individuals were included in the study. Capillaroscopic examination was performed with videocapillaroscope Videocap 3...
July 26, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28683299/effectiveness-and-feasibility-of-nailfold-microcirculation-test-to-screen-for-diabetic-peripheral-neuropathy
#9
Guotao Hu, Fanglong Zhai, Feifei Mo, Li He, Weiya Shen, Hailan Wang
AIMS: The nailfold microcirculation index (MI) is a non-invasive, objective, and highly sensitive blood capillary detection method. This study evaluated the diagnostic efficiency of the nailfold MI relative to the more subjective vibration perception threshold (VPT) examination for early diagnostic screening of diabetic peripheral neuropathy (DPN). METHODS: From February 2015 to February 2016, 227 diabetes mellitus patients and 39 healthy individuals were enrolled...
June 13, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28641551/nailfold-capillaroscopy-within-and-beyond-the-scope-of-connective-tissue-diseases
#10
Sevdalina Lambova, Ulf Müller-Ladner
Nailfold capillaroscopy is a noninvasive instrumental method for morphological analysis of the nutritive capillaries in the nailfold area. In rheumatology, it is a method of choice among instrumental modalities for differentiation of primary and secondary Raynaud's phenomenon (RP) in rheumatic diseases. RP is a common diagnostic problem in rheumatology. Defining the proper diagnosis is a prerequisite for administration of the appropriate treatment. Thus, nailfold capillaroscopic examination is of crucial importance for the every-day practice of the rheumatologists and is currently gaining increasing attention...
June 14, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28641550/bier-spots-report-of-two-cases-and-review-of-the-literature
#11
Hristo Dobrev, Desislava Nocheva
Bier spots are asymptomatic white anemic macules with irregular shape located on the upper limbs and less often on the lower limbs and trunkus. They are observed predominantly in youg males and may be idiopathic or associated with other conditions. We report two cases with Bier spots in which videodermatoscopy and nailfold capillaroscopy were performed. Patient 1 was a 34-year-old otherwise healthy male who presented with white spots on his upper limbs for 10 years. Dermoscopy revealed marked narrowing of skin capillaries within the borders of white macules whereas capillaroscopy pattern was normal...
June 14, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28619664/nailfold-capillaroscopic-changes-in-patients-with-idiopathic-pulmonary-arterial-hypertension-and-systemic-sclerosis-related-pulmonary-arterial-hypertension
#12
A Corrado, M Correale, N Mansueto, I Monaco, A Carriero, A Mele, R Colia, M Di Biase, F P Cantatore
Pulmonary arterial hypertension (PAH) represents one of the main clinical expressions of the vascular changes in systemic sclerosis (SSc). Lung microvascular changes can play a role in the pathogenesis of idiopathic PAH (IPAH) also. The aim of this study is to investigate the presence of capillaroscopic abnormalities in patients with IPAH and to evaluate the differences in capillary nailfold changes between patients with IPAH and patients with SSc with and without PAH. METHODS: 39 SSc patients (19 with PAH - SSc-PAH and 20 without - SSc-noPAH), 21 subjects with IPAH and 20 healthy subjects were recruited...
June 12, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28610600/the-cumulative-number-of-micro-haemorrhages-and-micro-thromboses-in-nailfold-videocapillaroscopy-is-a-good-indicator-of-disease-activity-in-systemic-sclerosis-a-validation-study-of-the-nemo-score
#13
Romina Andracco, Rosaria Irace, Eleonora Zaccara, Serena Vettori, Wanda Maglione, Antonella Riccardi, Francesca Pignataro, Roberta Ferrara, Domenico Sambataro, Gianluca Sambataro, Claudio Vitali, Gabriele Valentini, Nicoletta Del Papa
BACKGROUND: Some abnormalities in nailfold videocapillaroscopy (NVC), such as the presence of micro-haemorrhages (MHEs), micro-thromboses (MTs), giant capillaries (GCs) and reduction in the number of capillaries (nCs), suggest a disease activity (DA) phase in systemic sclerosis (SSc). In a previous paper, we showed that the number of micro-haemorrhages and micro-thromboses (the so-called NEMO score) was the NVC feature more closely associated with DA. The present study was aimed at validating the NEMO score as a measure of DA in patients with SSc...
June 13, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28578493/nailfold-videocapillaroscopy-results-in-patients-with-rheumatoid-arthritis
#14
Sinem Sag, Mustafa Serdar Sag, Ibrahim Tekeoglu, Ayhan Kamanli, Kemal Nas, Yıldıray Aydın
We aimed to analyse the nailfold capillaryscopy findings morphologically and examine their relationship with disease activity and demographic characteristics in patients with rheumatoid arthritis. In accordance with the 2010 ACR/EULAR classification criteria, 201 patients diagnosed with Romatoiad artrit (RA) and 50 healthy controls were included. We analysed capillaroscopic abnormalities such asmegacapillaries, haemorrhages, ramifications and avascular areas in patients affected with rheumatoid arthritis. The findings in our study are as follows: in 45...
June 4, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28514969/endothelial-progenitor-cell-number-is-not-decreased-in-34-children-with-juvenile-dermatomyositis-a-pilot-study
#15
Dong Xu, Akadia Kacha-Ochana, Gabrielle A Morgan, Chiang-Ching Huang, Lauren M Pachman
OBJECTIVE: A pilot study to determine endothelial progenitor cells (EPC) number in children with Juvenile Dermatomyositis (JDM). METHODS: After obtaining informed consent, the EPC number from 34 fasting children with definite/probable JDM at various stages of therapy-initially untreated, active disease on medication and clinically inactive, off medication-was compared with 13 healthy fasting pediatric controls. The EPC number was determined by fluorescence activated cell sorting (FACS), CD34(+)/VEGFR2(+)/CD45dim(-), and assessed in conjunction with clinical variables: disease activity scores (DAS), duration of untreated disease (DUD), TNF-α allelic polymorphism (A/G) at the promoter region of -308, number of nailfold capillary end row loop (ERL) and von Willebrand factor antigen (vWF:Ag)...
May 17, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28495471/quantitative-outcome-measures-for-systemic-sclerosis-related-microangiopathy-reliability-of-image-acquisition-in-nailfold-capillaroscopy
#16
Graham Dinsdale, Tonia Moore, Neil O'Leary, Michael Berks, Christopher Roberts, Joanne Manning, John Allen, Marina Anderson, Maurizio Cutolo, Roger Hesselstrand, Kevin Howell, Carmen Pizzorni, Vanessa Smith, Alberto Sulli, Marie Wildt, Christopher Taylor, Andrea Murray, Ariane L Herrick
BACKGROUND: Nailfold capillaroscopic parameters hold increasing promise as outcome measures for clinical trials in systemic sclerosis (SSc). Their inclusion as outcomes would often naturally require capillaroscopy images to be captured at several time points during any one study. Our objective was to assess repeatability of image acquisition (which has been little studied), as well as of measurement. METHOD: 41 patients (26 with SSc, 15 with primary Raynaud's phenomenon) and 10 healthy controls returned for repeat high-magnification (300×) videocapillaroscopy mosaic imaging of 10 digits one week after initial imaging (as part of a larger study of reliability)...
May 8, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28466674/nailfold-scleroderma-like-capillary-abnormalities-in-werner-syndrome-adult-progeria
#17
Francesca Ingegnoli, Chiara Crotti
No abstract text is available yet for this article.
March 1, 2017: Vascular Medicine
https://www.readbyqxmd.com/read/28414021/elliptical-broken-line-method-for-calculating-capillary-density-in-nailfold-capillaroscopy-proposal-and-evaluation
#18
Abdolamir Karbalaie, Farhad Abtahi, Alimohammad Fatemi, Mahnaz Etehadtavakol, Zahra Emrani, Björn-Erik Erlandsson
Nailfold capillaroscopy is a practical method for identifying and obtaining morphological changes in capillaries which might reveal relevant information about diseases and health. Capillaroscopy is harmless, and seems simple and repeatable. However, there is lack of established guidelines and instructions for acquisition as well as the interpretation of the obtained images; which might lead to various ambiguities. In addition, assessment and interpretation of the acquired images are very subjective. In an attempt to overcome some of these problems, in this study a new modified technique for assessment of nailfold capillary density is introduced...
April 14, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28386138/nailfold-digital-capillaroscopic-findings-in-patients-with-diffuse-and-limited-cutaneous-systemic-sclerosis
#19
Saeedeh Shenavandeh, Mahyar Yousefipour Haghighi, Mohammad Ali Nazarinia
BACKGROUND: Systemic sclerosis (SSc) is a chronic disease with microvascular damage. Nailfold capillaroscopy is a non-invasive method used for evaluating capillaries in SSc. Its findings could be related to the internal organ involvement and SSc course. In this study, we aimed to determine the association of the capillaroscopic patterns of nailfold capillaries with the disease subtypes of SSc, disease duration, and clinical manifestations. MATERIAL AND METHODS: Seventy patients with SSc (15 cases with diffuse cutaneous SSc [DcSSc] and 55 patients with limited SSc [LcSSc]) were studied...
2017: Reumatologia
https://www.readbyqxmd.com/read/28342234/critical-contribution-of-the-interleukin-6-signal-transducer-and-activator-of-transcription-3-axis-to-vasculopathy-associated-with-systemic-sclerosis
#20
Takashi Taniguchi, Yoshihide Asano, Takemichi Fukasawa, Ayumi Yoshizaki, Shinichi Sato
Reflecting the critical role of interleukin (IL)-6 in systemic sclerosis (SSc), tocilizumab, an anti-IL-6 receptor antibody, is currently under a global phase III trial against skin sclerosis of this disease. We here demonstrate that the IL-6/signal transducer and activator of transcription 3 axis is broadly activated in various cell types in the lesional skin of SSc patients irrespective of disease subtypes, especially in endothelial cells. Importantly, 12 monthly infusions of tocilizumab improved nailfold capillary changes as well as skin sclerosis in a patient with diffuse cutaneous SSc...
March 24, 2017: Journal of Dermatology
keyword
keyword
65289
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"