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https://www.readbyqxmd.com/read/28813964/brain-computer-interface-combining-eye-saccade-two-electrode-eeg-signals-and-voice-cues-to-improve-the-maneuverability-of-wheelchair
#1
Ker-Jiun Wang, Lan Zhang, Bo Luan, Hsiao-Wei Tung, Quanfeng Liu, Jiacheng Wei, Mingui Sun, Zhi-Hong Mao
Brain-computer interfaces (BCIs) largely augment human capabilities by translating brain wave signals into feasible commands to operate external devices. However, many issues face the development of BCIs such as the low classification accuracy of brain signals and the tedious human-learning procedures. To solve these problems, we propose to use signals associated with eye saccades and blinks to control a BCI interface. By extracting existing physiological eye signals, the user does not need to adapt his/her brain waves to the device...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813938/online-sparse-gaussian-process-based-human-motion-intent-learning-for-an-electrically-actuated-lower-extremity-exoskeleton
#2
Yi Long, Zhi-Jiang Du, Chao-Feng Chen, Wei Dong, Wei-Dong Wang
The most important step for lower extremity exoskeleton is to infer human motion intent (HMI), which contributes to achieve human exoskeleton collaboration. Since the user is in the control loop, the relationship between human robot interaction (HRI) information and HMI is nonlinear and complicated, which is difficult to be modeled by using mathematical approaches. The nonlinear approximation can be learned by using machine learning approaches. Gaussian Process (GP) regression is suitable for high-dimensional and small-sample nonlinear regression problems...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813886/exploratory-design-of-a-compliant-mechanism-for-a-dynamic-hand-orthosis-lessons-learned
#3
Ronald A Bos, Dick H Plettenburg, Just L Herder
This study does not describe a success-story. Instead, it describes an exploratory process and the lessons learned while designing a compliant mechanism for a dynamic hand orthosis. Tools from engineering optimization and rapid prototyping techniques were used, with the goal to design a mechanism to compensate for hypertonic or contracted finger muscles. Results show that the mechanism did not reach its design constraints, mostly because it could not provide for the necessary stiffness and compliance at the same time...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813804/leap-motion-evaluation-for-assessment-of-upper-limb-motor-skills-in-parkinson-s-disease
#4
A H Butt, E Rovini, C Dolciotti, P Bongioanni, G De Petris, F Cavallo
The main goal of this study is to investigate the potential of the Leap Motion Controller (LMC) for the objective assessment of motor dysfunctioning in patients with Parkinson's disease (PwPD). The most relevant clinical signs in Parkinson's Disease (PD), such as slowness of movements, frequency variation, amplitude variation, and speed, were extracted from the recorded LMC data. Data were clinically quantified using the LMC software development kit (SDK). In this study, 16 PwPD subjects and 12 control healthy subjects were involved...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813792/there-is-plenty-of-room-for-motor-learning-at-the-bottom-of-the-fugl-meyer-acquisition-of-a-novel-bimanual-wheelchair-skill-after-chronic-stroke-using-an-unmasking-technology
#5
Yasemin Sarigul-Klijn, Joan Lobo-Prat, Brendan W Smith, Sage Thayer, Daniel Zondervan, Vicky Chan, Oliver Stoller, David J Reinkensmeyer
Many people with a stroke have a severely paretic arm, and it is often assumed that they are unable to learn novel, skilled behaviors that incorporate use of that arm. Here, we show that a group of people with chronic stroke (n = 5, upper extremity Fugl-Meyer scores: 31, 30, 26, 22, 8) learned to use their impaired arm to propel a novel, yoked-clutch lever drive wheelchair. Over six daily training sessions, each involving about 134 training movements with their "useless" arm, the users gradually achieved a 3-fold increase in wheelchair speed on average, with a 4-6 fold increase for three of the participants...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813537/metabolite-patterns-predicting-sex-and-age-in-participants-of-the-karlsruhe-metabolomics-and-nutrition-karmen-study
#6
Manuela J Rist, Alexander Roth, Lara Frommherz, Christoph H Weinert, Ralf Krüger, Benedikt Merz, Diana Bunzel, Carina Mack, Björn Egert, Achim Bub, Benjamin Görling, Pavleta Tzvetkova, Burkhard Luy, Ingrid Hoffmann, Sabine E Kulling, Bernhard Watzl
Physiological and functional parameters, such as body composition, or physical fitness are known to differ between men and women and to change with age. The goal of this study was to investigate how sex and age-related physiological conditions are reflected in the metabolome of healthy humans and whether sex and age can be predicted based on the plasma and urine metabolite profiles. In the cross-sectional KarMeN (Karlsruhe Metabolomics and Nutrition) study 301 healthy men and women aged 18-80 years were recruited...
2017: PloS One
https://www.readbyqxmd.com/read/28813352/optimizing-motivation-and-attention-for-motor-performance-and-learning
#7
REVIEW
Rebecca Lewthwaite, Gabriele Wulf
We review three lines of recent research at an intersection of motor learning and sport psychology as they relate to motor skill acquisition: enhanced expectancies, autonomy support, and external attentional focus. Findings within these lines of research have been integrated into a new theory, the OPTIMAL (Optimizing Performance through Intrinsic Motivation and Attention for Learning) theory (i.e., OPTIMAL theory, Wulf and Lewthwaite, 2016), and have been applied in motor skill acquisition and performance. Implications range from more effective skill development in children and novice performers to athletes and performers in many fields, including clinical rehabilitation...
August 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28812307/the-development-of-perceptual-averaging-learning-what-to-do-not-just-how-to-do-it
#8
Pete R Jones, Tessa M Dekker
The mature visual system condenses complex scenes into simple summary statistics (e.g., average size, location, orientation, etc.). However, children, often perform poorly on perceptual averaging tasks. Children's difficulties are typically thought to represent the suboptimal implementation of an adult-like strategy. This paper examines another possibility: that children actually make decisions in a qualitatively different way to adults (optimal implementation of a non-ideal strategy). Ninety children (6-7, 8-9, 10-11 years) and 30 adults were asked to locate the middle of randomly generated dot-clouds...
August 15, 2017: Developmental Science
https://www.readbyqxmd.com/read/28812274/oxytocin-and-anxiety-disorders
#9
Michael G Gottschalk, Katharina Domschke
In the present chapter, we review the literature focusing on oxytocin (OT)-centered research in anxiety spectrum conditions, comprising separation anxiety disorder, specific phobias, social anxiety disorder (SAD), panic disorder, generalized anxiety disorder, and anxiety-related endophenotypes (e.g., trust behavior, behavioral inhibition, neuroticism, and state/trait anxiety). OT receptor gene (OXTR) polymorphisms have been implicated in gene-environment interactions with attachment style and childhood maltreatment and to influence clinical outcomes, including SAD intensity and limbic responsiveness...
August 16, 2017: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/28812154/robotic-versus-laparoscopic-versus-open-colorectal-surgery-towards-defining-criteria-to-the-right-choice
#10
Matthew Zelhart, Andreas M Kaiser
OBJECTIVE: Analysis of various parameters related to the patient, the disease, and the needed surgical maneuvers to develop guidance for preoperative selection of the appropriate and the best approach for a given patient. Rapid advances in minimally invasive surgical technology are fascinating and challenging alike. It can be difficult for surgeons to keep up with new modalities that come on to the market place and to assess their true value, i.e., distinguish between fashionable trends versus scientific evidence...
August 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28811737/learning-and-developing-individual-exercise-skills-l-a-d-i-e-s-for-a-better-life-a-church-based-physical-activity-intervention-baseline-participant-characteristics
#11
Melicia C Whitt-Glover, Moses V Goldmon, Ziya Gizlice, Daniel P Heil, Njeri Karanja
OBJECTIVE: Physical activity (PA) is beneficial for health, yet most African American women do not achieve recommended levels. Successful, sustainable strategies could help to address disparities in health outcomes associated with low levels of PA. The Learning and Developing Individual Exercise Skills (L.A.D.I.E.S.) for a Better Life study compared a faith-based and a secular intervention for increasing PA with a self-guided control group. DESIGN SETTING AND PARTICIPANTS: This cluster randomized, controlled trial was conducted from 2010 - 2011 in African American churches (n=31) in suburban North Carolina...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/28811732/exposure-to-and-use-of-electronic-cigarettes-does-language-matter
#12
Paul Wada, Chun Nok Lam, Elizabeth Burner, Sophie Terp, Michael Menchine, Sanjay Arora
OBJECTIVES: To determine whether patients who are English proficient become aware of e-cigarettes through different marketing tactics and have dissimilar patterns of use than patients who are non-English speaking. DESIGN: This was a cross-sectional study surveying adult English- and Spanish-speaking patients. ANOVA and chi-squared tests were used to examine differences between groups. SETTING: A large public, safety-net hospital in Los Angeles County, California...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/28811341/the-u-s-culture-collection-network-responding-to-the-requirements-of-the-nagoya-protocol-on-access-and-benefit-sharing
#13
REVIEW
Kevin McCluskey, Katharine B Barker, Hazel A Barton, Kyria Boundy-Mills, Daniel R Brown, Jonathan A Coddington, Kevin Cook, Philippe Desmeth, David Geiser, Jessie A Glaeser, Stephanie Greene, Seogchan Kang, Michael W Lomas, Ulrich Melcher, Scott E Miller, David R Nobles, Kristina J Owens, Jerome H Reichman, Manuela da Silva, John Wertz, Cale Whitworth, David Smith
The U.S. Culture Collection Network held a meeting to share information about how culture collections are responding to the requirements of the recently enacted Nagoya Protocol on Access to Genetic Resources and the Fair and Equitable Sharing of Benefits Arising from their Utilization to the Convention on Biological Diversity (CBD). The meeting included representatives of many culture collections and other biological collections, the U.S. Department of State, U.S. Department of Agriculture, Secretariat of the CBD, interested scientific societies, and collection groups, including Scientific Collections International and the Global Genome Biodiversity Network...
August 15, 2017: MBio
https://www.readbyqxmd.com/read/28811227/the-chemotherapeutic-agent-paclitaxel-selectively-impairs-reversal-learning-while-sparing-prior-learning-new-learning-and-episodic-memory
#14
Danielle Panoz-Brown, Lawrence M Carey, Alexandra E Smith, Meredith Gentry, Christina M Sluka, Hannah E Corbin, Jie-En Wu, Andrea G Hohmann, Jonathon D Crystal
Chemotherapy is widely used to treat patients with systemic cancer. The efficacy of cancer therapies is frequently undermined by adverse side effects that have a negative impact on the quality of life of cancer survivors. Cancer patients who receive chemotherapy often experience chemotherapy-induced cognitive impairment across a variety of domains including memory, learning, and attention. In the current study, the impact of paclitaxel, a taxane derived chemotherapeutic agent, on episodic memory, prior learning, new learning, and reversal learning were evaluated in rats...
August 12, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28811178/acute-%C3%AE-9-tetrahydrocannabinol-administration-in-female-rats-attenuates-immediate-responses-following-losses-but-not-multi-trial-reinforcement-learning-from-wins
#15
Scott A Wong, Sienna H Randolph, Victorita E Ivan, Aaron J Gruber
Δ-9-tetrahydrocannabinol (THC) is the main psychoactive component of marijuana and has potent effects on decision-making, including a proposed reduction in cognitive flexibility. We demonstrate here that acute THC administration differentially affects some of the processes that contribute to cognitive flexibility. Specifically, THC reduces lose-shift responding in which female rats tend to immediately shift choice responses away from options that result in reward omission on the previous trial. THC, however, did not impair the ability of rats to flexibly bias responses toward feeders with higher probability of reward in a reversal task...
August 12, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28810969/a-review-of-the-effectiveness-of-a-combat-and-operational-stress-control-restoration-center-in-afghanistan
#16
Jason L Judkins, Devvon L Bradley
BACKGROUND: The management of Combat and Operational Stress Reactions (COSR) within an operational environment is a multidimensional process. The aim is to help prevent behavioral health problems, preserve combat power, and increase return to duty rates for combat stress related casualties. In some COSR cases, enhanced services are required and the Combat and Operational Stress Control (COSC) Clinic refers Service Members (SMs) to the Freedom Restoration Clinic (FRC). The purpose was to describe a deployed restoration center in Afghanistan and examine the long-term effectiveness of those services...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810112/patient-and-physician-perceptions-of-genetic-testing-in-primary-care
#17
Samuel A Evenson, H Eugene Hoyme, Jan E Haugen-Rogers, Eric A Larson, Susan E Puumala
INTRODUCTION: The convergence of biomedical informatics and translational genomics is changing the way we practice. Primary care will play a pivotal role in this transformation. We therefore sought to assess general knowledge about genetic testing among outpatient internal medicine providers, and the patients that they serve across a five state region in the Midwest. METHODS: One thousand take-home paper surveys were created and distributed to internal medicine patients at 13 Midwestern clinics...
November 2016: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28809716/structured-weak-semantic-space-construction-for-visual-categorization
#18
Chunjie Zhang, Jian Cheng, Qi Tian
Visual features have been widely used for image representation and categorization. However, visual features are often inconsistent with human perception. Besides, constructing explicit semantic space is still an open problem. To alleviate these two problems, in this paper, we propose to construct structured weak semantic space for image representation. Exemplar classifier is first trained to separate each training image from other images for weak semantic space construction. However, each exemplar classifier separates one training image from other images, and it only has limited semantic separability...
August 11, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28809673/heterogeneous-face-attribute-estimation-a-deep-multi-task-learning-approach
#19
Hu Han, Anil K Jain, Shiguang Shan, Xilin Chen
Face attribute estimation has many potential applications in video surveillance, face retrieval, and social media. While a number of methods have been proposed for face attribute estimation, most of them did not explicitly consider the attribute correlation and heterogeneity (e.g., ordinal vs. nominal and holistic vs. local) during feature representation learning. In this paper, we present a Deep Multi-Task Learning (DMTL) approach to jointly estimate multiple heterogeneous attributes from a single face image...
August 10, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28808833/long-acting-ionically-paired-embonate-based-nanocrystals-of-donepezil-for-the-treatment-of-alzheimer-s-disease-a-proof-of-concept-study
#20
Naresh Mittapelly, Maharshi Thalla, Gitu Pandey, Venkatesh Teja Banala, Shweta Sharma, Abhishek Arya, Sandeep Mishra, Kalyan Mitra, Shubha Shukla, Prabhat Ranjan Mishra
PURPOSE: The aim of the present study was to prepare a patient friendly long acting donepezil (D) nanocrystals (NCs) formulation, with a high payload for i.m administration. As the native D hydrochloride salt has high aqueous solubility it is necessary to increase its hydrophobicity prior to the NCs formation. METHODS: D was ionically paired with embonic acid (E) in aqueous media and was successfully characterized using techniques like DSC, PXRD, FT-IR, NMR etc...
August 14, 2017: Pharmaceutical Research
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