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Bolla trial

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https://www.readbyqxmd.com/read/27892626/withdrawn-root-canal-posts-for-the-restoration-of-root-filled-teeth
#1
REVIEW
Marc Bolla, Michele Muller-Bolla, Cybele Borg, Laurence Lupi-Pegurier, Olivier Laplanche, Eric Leforestier
BACKGROUND: The foundation for the reconstruction of endodontically-treated teeth can be provided by a metal or a non-metal post and core system but no guidelines exist for choosing one or the other in particular clinical cases. OBJECTIVES: To assess the effectiveness of different post and core systems for the restoration of endodontically-treated teeth. The primary objective of this review was to compare the clinical failure rates of the different types of posts...
November 28, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27733723/detection-of-occlusal-carious-lesion-using-the-soprolife-%C3%A2-camera-a-systematic-review
#2
Sophie Doméjean, Julie Rongier, Michéle Muller-Bolla
The aim of this systematic review was to assess the in vivo scientific evidence regarding the ability of a recently developed light fluorescence device, SoproLife(®) (Sopro-Acteon group, La Ciotat, France) in detecting occlusal carious lesions. The PubMed database was searched for in vivo trials that evaluated the validity of the SoproLife(®) camera for the detection of occlusal carious lesions. Among the 11 articles originally identified with the keyword "Soprolife," only three articles were included. The three included surveys used the International Caries Detection and Assessment System (ICDAS)-II criteria as gold standard for the assessment of SoproLife(®) compared or not to other detection devices (DIAGNOdent(®) and Spectra Caries Detection Aid(®))...
September 1, 2016: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/27532506/aesthetic-preformed-paediatric-crowns-systematic-review
#3
Elody Aiem, Violaine Smaïl-Faugeron, Michèle Muller-Bolla
BACKGROUND: Different aesthetic preformed crowns (APC) are proposed to restore decayed and damaged primary teeth because the stainless steel crowns (SSCs) do not satisfy parents concerned about aesthetic. AIM: The objective was to evaluate the clinical effectiveness of all types of APC for restoring primary teeth compared with conventional filling materials or other types of crowns. DESIGN: Relevant articles were searched in electronic databases of PubMed via MEDLINE and the Cochrane central register of controlled trials...
August 17, 2016: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/27527342/one-step-partial-or-complete-caries-removal-and-bonding-with-antibacterial-or-traditional-self-etch-adhesives-study-protocol-for-a-randomized-controlled-trial
#4
Cyril Villat, Jean-Pierre Attal, Nathalie Brulat, Franck Decup, Sophie Doméjean, Elisabeth Dursun, Hélène Fron-Chabouis, Bruno Jacquot, Michèle Muller Bolla, Nelly Plasse-Pradelle, Laurent Roche, Delphine Maucort-Boulch, Patrice Nony, Kerstin Gritsch, Pierre Millet, François Gueyffier, Brigitte Grosgogeat
BACKGROUND: Current concepts in conservative dentistry advocate minimally invasive dentistry and pulp vitality preservation. Moreover, complete removal of carious dentin in deep carious lesions often leads to pulp exposure and root canal treatment, despite the absence of irreversible pulp inflammation. For years, partial caries removal has been performed on primary teeth, but little evidence supports its effectiveness for permanent teeth. Furthermore, the recent development of new antibacterial adhesive systems could be interesting in the treatment of such lesions...
August 15, 2016: Trials
https://www.readbyqxmd.com/read/27377108/indirect-pulp-capping-versus-pulpotomy-for-treating-deep-carious-lesions-approaching-the-pulp-in-primary-teeth-a-systematic-review
#5
REVIEW
V Smaïl-Faugeron, A Porot, M Muller-Bolla, F Courson
AIM: To assess dental practice regarding the use of indirect pulp capping or pulpotomy in children with deep carious lesions approaching the pulp in primary teeth and to compare the efficacy of the two pulp treatments. METHODS: HASH(0x447b9d0) STUDY DESIGN: Systematic review. We searched the Cochrane Library, PubMed via MEDLINE, and EMBASE as well as the reference lists of included reports and ClinicalTrials.gov (for ongoing trials). Eligible studies were surveys of dental practice sent to dentists regarding the use of indirect pulp capping and pulpotomy in children with deep carious lesions approaching the pulp in primary teeth and any type of clinical study...
June 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27349618/effectiveness-of-school-based-dental-sealant-programs-among-children-from-low-income-backgrounds-a-pragmatic-randomized-clinical-trial-with-a-follow-up-of-3-years
#6
Michèle Muller-Bolla, Audrey Pierre, Laurence Lupi-Pégurier, Ana M Velly
AIM: A split-mouth randomized clinical trial was carried out to assess the effectiveness of a school-based dental sealant (SBDS) program for French children from low-income backgrounds within 3 years of follow-up. The secondary objectives were to determine the risk factors for the occurrence of new carious lesions (ICDAS 3-6) on first permanent molars, to evaluate the effectiveness of the program according to risk factors and to assess sealant retention. METHODS: The study included 276 6- to 7-year old pupils (457 pairs of first permanent molars) from Nice...
October 2016: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/27162801/efficacy-of-local-use-of-probiotics-as-an-adjunct-to-scaling-and-root-planing-in-chronic-periodontitis-and-halitosis-a-randomized-controlled-trial
#7
Soumya Penala, Butchibabu Kalakonda, Krishnajaneya Reddy Pathakota, Avula Jayakumar, Pradeep Koppolu, Bolla Vijaya Lakshmi, Ruchi Pandey, Ashank Mishra
OBJECTIVE: Periodontitis is known to have multifactorial etiology, involving interplay between environmental, host and microbial factors. The current treatment approaches are aimed at reducing the pathogenic microorganisms. Administration of beneficial bacteria (probiotics) has emerged as a promising concept in the prevention and treatment of periodontitis. Thus, the aim of the present study is to evaluate the efficacy of the local use of probiotics as an adjunct to scaling and root planing (SRP) in the treatment of patients with chronic periodontitis and halitosis...
April 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/26976418/short-androgen-suppression-and-radiation-dose-escalation-for-intermediate-and-high-risk-localized-prostate-cancer-results-of-eortc-trial-22991
#8
Michel Bolla, Philippe Maingon, Christian Carrie, Salvador Villa, Petros Kitsios, Philip M P Poortmans, Santhanam Sundar, Elzbieta M van der Steen-Banasik, John Armstrong, Jean-François Bosset, Fernanda G Herrera, Bradley Pieters, Annerie Slot, Amit Bahl, Rahamim Ben-Yosef, Dirk Boehmer, Christopher Scrase, Laurette Renard, Emad Shash, Corneel Coens, Alphonsus C M van den Bergh, Laurence Collette
PURPOSE: Up to 30% of patients who undergo radiation for intermediate- or high-risk localized prostate cancer relapse biochemically within 5 years. We assessed if biochemical disease-free survival (DFS) is improved by adding 6 months of androgen suppression (AS; two injections of every-3-months depot of luteinizing hormone-releasing hormone agonist) to primary radiotherapy (RT) for intermediate- or high-risk localized prostate cancer. PATIENTS AND METHODS: A total of 819 patients staged: (1) cT1b-c, with prostate-specific antigen (PSA) ≥ 10 ng/mL or Gleason ≥ 7, or (2) cT2a (International Union Against Cancer TNM 1997), with no involvement of pelvic lymph nodes and no clinical evidence of metastatic spread, with PSA ≤ 50 ng/mL, were centrally randomized 1:1 to either RT or RT plus AS started on day 1 of RT...
May 20, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/26163031/split-mouth-and-parallel-arm-trials-to-compare-pain-with-intraosseous-anaesthesia-delivered-by-the-computerised-quicksleeper-system-and-conventional-infiltration-anaesthesia-in-paediatric-oral-healthcare-protocol-for-a-randomised-controlled-trial
#9
RANDOMIZED CONTROLLED TRIAL
Violaine Smaïl-Faugeron, Michèle Muller-Bolla, Jean-Louis Sixou, Frédéric Courson
INTRODUCTION: Local anaesthesia is commonly used in paediatric oral healthcare. Infiltration anaesthesia is the most frequently used, but recent developments in anaesthesia techniques have introduced an alternative: intraosseous anaesthesia. We propose to perform a split-mouth and parallel-arm multicentre randomised controlled trial (RCT) comparing the pain caused by the insertion of the needle for the injection of conventional infiltration anaesthesia, and intraosseous anaesthesia by the computerised QuickSleeper system, in children and adolescents...
July 10, 2015: BMJ Open
https://www.readbyqxmd.com/read/25099759/pulp-treatment-for-extensive-decay-in-primary-teeth
#10
REVIEW
Violaine Smaïl-Faugeron, Frédéric Courson, Pierre Durieux, Michele Muller-Bolla, Anne-Marie Glenny, Helene Fron Chabouis
BACKGROUND: In children, dental caries is among the most prevalent chronic diseases worldwide. Pulp interventions are indicated for extensive tooth decay. Depending on the severity of the disease, three pulp treatment techniques are available: direct pulp capping, pulpotomy and pulpectomy. After treatment, the cavity is filled with a medicament.This is an update of a Cochrane review first published in 2003. The previous review found insufficient evidence regarding the relative efficacy of these interventions, combining one pulp treatment technique and one medicament...
2014: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/24820932/recruiting-long-term-survivors-of-european-organisation-for-research-and-treatment-of-cancer-phase-iii-clinical-trials-into-quality-of-life-studies-challenges-and-opportunities
#11
RANDOMIZED CONTROLLED TRIAL
Marieke van Leeuwen, Fabio Efficace, Sophie D Fosså, Michel Bolla, Ugo De Giorgi, Ronald de Wit, Bernhard Holzner, Lonneke V van de Poll-Franse, Hendrik van Poppel, Jeff White, Laurence Collette, Susanne Osanto, Neil K Aaronson
OBJECTIVES: In this pilot study we evaluated the feasibility of and methods for assessing the quality of life of long term survivors of European Organisation for Research and Treatment of Cancer (EORTC) phase III clinical trials. Here we report the results pertaining to the feasibility of conducting such research. METHODS: In this cross-sectional study, we recruited long-term, disease-free survivors from two mature EORTC clinical trials in testicular and prostate cancer from centres in Northern and Southern Europe, and the United Kingdom (UK)...
July 2014: European Journal of Cancer
https://www.readbyqxmd.com/read/24679462/commentary-on-postoperative-radiotherapy-after-radical-prostatectomy-for-high-risk-prostate-cancer-long-term-results-of-a-randomised-controlled-trial-eortc-trial-22911-bolla-m-van-poppel-h-tombal-b-vekemans-k-da-pozzo-l-de-reijke-tm-verbaeys-a-bosset-jf-van
#12
COMMENT
Mark A Ritter
BACKGROUND: We report the long-term results of a trial of immediate postoperative irradiation versus a wait-and-see policy in patients with prostate cancer extending beyond the prostate, to confirm whether previously reported progression-free survival was sustained. METHODS: This randomised, phase 3, controlled trial recruited patients aged 75 years or younger with untreated cT0-3 prostate cancer (WHO performance status 0 or 1) from 37 institutions across Europe...
April 2014: Urologic Oncology
https://www.readbyqxmd.com/read/24440473/fluorouracil-based-adjuvant-chemotherapy-after-preoperative-chemoradiotherapy-in-rectal-cancer-long-term-results-of-the-eortc-22921-randomised-study
#13
RANDOMIZED CONTROLLED TRIAL
Jean-François Bosset, Gilles Calais, Laurent Mineur, Philippe Maingon, Suzana Stojanovic-Rundic, René-Jean Bensadoun, Etienne Bardet, Alexander Beny, Jean-Claude Ollier, Michel Bolla, Dominique Marchal, Jean-Luc Van Laethem, Vincent Klein, Jordi Giralt, Pierre Clavère, Christoph Glanzmann, Patrice Cellier, Laurence Collette
BACKGROUND: EORTC trial 22921 examined the addition of preoperative or postoperative chemotherapy to preoperative radiotherapy in patients with rectal cancer. After a median follow-up of 5 years, chemotherapy-irrespective of timing-significantly improved local control. Adjuvant chemotherapy did not improve survival, but the Kaplan-Meier curves diverged, suggesting possible delayed benefit. Here, we report the updated long-term results. METHODS: We randomly assigned patients with clinical stage T3 or T4 resectable rectal cancer to receive preoperative radiotherapy with or without concomitant chemotherapy before surgery followed by either adjuvant chemotherapy or surveillance...
February 2014: Lancet Oncology
https://www.readbyqxmd.com/read/24207135/eau-guidelines-on-prostate-cancer-part-1-screening-diagnosis-and-local-treatment-with-curative-intent-update-2013
#14
Axel Heidenreich, Patrick J Bastian, Joaquim Bellmunt, Michel Bolla, Steven Joniau, Theodor van der Kwast, Malcolm Mason, Vsevolod Matveev, Thomas Wiegel, F Zattoni, Nicolas Mottet
CONTEXT: The most recent summary of the European Association of Urology (EAU) guidelines on prostate cancer (PCa) was published in 2011. OBJECTIVE: To present a summary of the 2013 version of the EAU guidelines on screening, diagnosis, and local treatment with curative intent of clinically organ-confined PCa. EVIDENCE ACQUISITION: A literature review of the new data emerging from 2011 to 2013 has been performed by the EAU PCa guideline group...
January 2014: European Urology
https://www.readbyqxmd.com/read/24046823/toothbrushing-methods-to-use-in-children-a-systematic-review
#15
REVIEW
Michèle Muller-Bolla, Frédéric Courson
PURPOSE: To identify the most effective methods of toothbrushing in children, assessed according to their ability to remove dental plaque. MATERIALS AND METHODS: After electronic research, randomised clinical studies in children which compared different toothbrushing techniques or different frequencies with the same technique were included. The evaluation criterion was plaque index. RESULTS: Six of 534 identified articles were included. Because the protocols differed, regrouping of data was not possible...
2013: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/23972524/early-salvage-radiotherapy-following-radical-prostatectomy
#16
REVIEW
David Pfister, Michel Bolla, Alberto Briganti, Peter Carroll, Cesare Cozzarini, Steven Joniau, Hein van Poppel, Mack Roach, Andrew Stephenson, Thomas Wiegel, Michael J Zelefsky
CONTEXT: Depending on the pathologic tumour stage, up to 60% of prostate cancer patients who undergo radical prostatectomy will develop biochemical relapse and require further local treatment. OBJECTIVES: We reviewed the results of early salvage radiation therapy (RT), defined as prostate-specific antigen (PSA) values prior to RT ≤ 0.5 ng/ml in the setting of lymph node-negative disease. EVIDENCE ACQUISITION: Ten retrospective studies, including one multicentre analysis, were used for this analysis...
June 2014: European Urology
https://www.readbyqxmd.com/read/23915463/words-of-wisdom-re-high-risk-prostate-cancer-treated-with-pelvic-radiotherapy-and-36-versus-18-months-of-androgen-blockade-results-of-a-phase-iii-randomized-study-abstract-3
#17
https://www.readbyqxmd.com/read/23707151/quality-assurance-of-the-eortc-22043-30041-trial-in-post-operative-radiotherapy-in-prostate-cancer-results-of-the-dummy-run-procedure
#18
Paul A Fenton, Coen Hurkmans, Akos Gulyban, Jorien van der Leer, Oscar Matzinger, Philip Poortmans, Laurence Collette, Michel Bolla
BACKGROUND AND PURPOSE: The EORTC 22043-30041 trial investigates the role of the addition of androgen suppression to post-operative radiotherapy in patients who have undergone radical prostatectomy. As part of the quality assurance of radiotherapy (QART) a Dummy Run (DR) procedure was performed. MATERIALS AND METHOD: The protocol included detailed and published delineation guidelines. Participating institutions digitally submitted radiotherapy treatment volumes and a treatment plan for a standard clinical case...
June 2013: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/23673512/high-risk-prostate-cancer-combination-of-high-dose-high-precision-radiotherapy-and-androgen-deprivation-therapy
#19
Michel Bolla, Camille Verry, Jean-Alexandre Long
PURPOSE OF REVIEW: High-risk prostate cancer (PCa) harbours a risk of local, regional and systemic relapse requiring the combination of a loco-regional treatment such as external beam radiotherapy for controlling the pelvic-confined disease, combined with an androgen deprivation therapy (ADT) to potentiate irradiation and to destroy the infraclinical androgen-dependent disease outside the irradiated volume. RECENT FINDINGS: Many phase III randomized trials issued from the Radiation Therapy Oncology Group (USA) and from the EORTC Radiation Oncology Group have paved the way for establishing the indications of this combined approach...
July 2013: Current Opinion in Urology
https://www.readbyqxmd.com/read/23300955/development-of-a-core-set-of-outcomes-for-randomized-controlled-trials-with-multiple-outcomes-example-of-pulp-treatments-of-primary-teeth-for-extensive-decay-in-children
#20
REVIEW
Violaine Smaïl-Faugeron, Hélène Fron Chabouis, Pierre Durieux, Jean-Pierre Attal, Michèle Muller-Bolla, Frédéric Courson
OBJECTIVES: Evidence-based comparisons of interventions can be challenging because of the diversity of outcomes in randomized controlled trials (RCTs). We aimed to describe outcomes in RCTs assessing pulp treatments for primary teeth and to develop a core set of component outcomes to be part of composite outcome defining the failure of a pulp treatment. METHODS: We systematically reviewed articles of RCTs comparing pulp treatments for primary molars published up to February 2012...
2013: PloS One
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