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https://www.readbyqxmd.com/read/28721006/incidence-of-outer-retinal-tubulation-in-eyes-with-choroidal-neovascularization-under-intravitreal-anti-vascular-endothelial-growth-factor-therapy-in-a-japanese-population
#1
Seiji Takagi, Michiko Mandai, Noriko Miyamoto, Akihiro Nishida, Yasuhiko Hirami, Hirofumi Uyama, Midori Yamamoto, Masayo Takahashi, Goji Tomita, Yasuo Kurimoto
PURPOSE: The purpose of this study was to investigate the occurrence of outer retinal tubulation (ORT) among patients with different types of choroidal neovascularization (CNV) over time. MATERIALS AND METHODS: In this retrospective chart review, disease type was classified as typical age-related macular degeneration (t-AMD), polypoidal choroidal vasculopathy (PCV), retinal angiomatous proliferation (RAP), or myopic CNV (mCNV). Spectral domain-optical coherence tomography (SD-OCT) images were evaluated for the appearance of ORT and subretinal fibrosis and fluid...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28698359/egfr-down-regulation-after-anti-egfr-therapy-predicts-the-anti-tumor-effect-in-colorectal-cancer
#2
Yasuyuki Okada, Tetsuo Kimura, Tadahiko Nakagawa, Koichi Okamoto, Akira Fukuya, Takahiro Goji, Shota Fujimoto, Masahiro Sogabe, Hiroshi Miyamoto, Naoki Muguruma, Yasushi Tsuji, Toshiya Okahisa, Tetsuji Takayama
Anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb) is reported to induce EGFR internalization in colorectal cancer (CRC) cells. However, the biological relevance of EGFR internalization with anti-EGFR mAb is unknown. Therefore, the relevance of EGFR downregulation with anti-EGFR mAb to anti-tumor activity in CRC cells was investigated. Quantification of EGFR on the cell surface before cetuximab treatment was assessed by flow cytometry, and its growth-inhibitory effects were measured by trypan blue-exclusion, in 10 RAS, BRAF wild-type CRC cell lines, but there was no significant correlation between EGFR number and its growth-inhibitory effect...
July 11, 2017: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/28685012/lycium-barbarum-reduces-abdominal-fat-and-improves-lipid-profile-and-antioxidant-status-in-patients-with-metabolic-syndrome
#3
Mayara Zagonel de Souza Zanchet, Geisson Marcos Nardi, Letícia de Oliveira Souza Bratti, Fabíola Branco Filippin-Monteiro, Claudriana Locatelli
Natural antioxidants present in fruits have attracted considerable interest due to their presumed safety and potential nutritional value. Even though antioxidant activities of many fruits have been reported, the effects of phytochemicals of goji berry (GB) in patients with metabolic syndrome have not been investigated. In this study, we examined anthropometric and biochemical parameters in patients with metabolic syndrome after the consumption of GB. The patients were divided into two groups, control (C) and supplemented (S), and followed up for 45 days...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28655659/fungal-chitosan-and-lycium-barbarum-extract-as-anti-listeria-and-quality-preservatives-in-minced-catfish
#4
Mohammed S Alsaggaf, Shaaban H Moussa, Nihal M Elguindy, Ahmed A Tayel
Listeria monocytogenes is a foodborne bacterial pathogen that causes serious health risks. Chitosan (Ch) is a bioactive polymer that could be effectively applied for foodstuffs biopreservation. Lycium barbarum (Goji berry) is ethnopharmaceutical fruit that have diverse health protecting benefits. Chitosan was produced from A. niger and employed with L. barbarum extract (LBE) as blends for Listeria control and quality biopreservation of African catfish mince (Clarias gariepinus). Chitosan could utterly control L...
June 24, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28646833/the-use-of-fruit-extracts-for-production-of-apple-chips-with-enhanced-antioxidant-activity
#5
Tomasz Tarko, Aleksandra Duda-Chodak, Dorota Semik-Szczurak
Background: Style and pace of life make consumers more willing to reach for snack products. This group of processed food includes, among others, fruit chips. Due to the increasing incidence of diseases associated with the excessive exposure to free radicals foods enriched with antioxidant compounds, eg. polyphenols, can be introduced into the sale. Objective: The aim of the study was to use the fruit extracts for the production of apple chips with enhanced antioxidant activity...
2017: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/28629290/functional-foods-how-functional-are-they-a-case-report-of-supplement-induced-psychosis
#6
Priyanka Yadav, Kyle Stigall, Hannah E Johnson, Abner O Rayapati, Nitin Chopra
There is rising evidence of patients' use of alternative and complementary medicine. The percentage of the U.S. population who used at least one dietary supplement increased from 42% in 1988-1994 to 53% in 2003-2006. We present a case of an Asian female in her 40s, with no previous psychiatric illness, who presented to the emergency room following a brief psychotic episode, during which she self-amputated the tips of her fingers, after using multivitamins and herbal supplements including ginseng, gui yuan rou (Chinese herb), astaxanthin, goji (Chinese fruit), selenium, saw palmetto, grape seed extract, citrus bioflavanoid, lutein (zeaxantin), resvexatrol, sun chlorella, spirulina powder, phytoceramides, phytoestrogen, glucosatrin, bromelain plus, and American bee pollen...
August 2016: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28618341/analytical-profiling-of-selected-antioxidants-and-total-antioxidant-capacity-of-goji-lycium-spp-berries
#7
Michele Protti, Isacco Gualandi, Roberto Mandrioli, Sergio Zappoli, Domenica Tonelli, Laura Mercolini
Goji berries and derived products represent a relevant source of micronutrients, most of which are natural antioxidants and contribute to the high nutritional quality of these fruits. Three brands of dried goji berries have been analysed by a multidisciplinary approach to get an insight into both their content of selected antioxidants and their antioxidant capacity (AC). The former goal has been achieved by developing a liquid chromatographic method coupled to mass spectrometry and combined to a fast solid phase extraction...
September 5, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28577950/association-of-mth1-expression-with-the-tumor-malignant-potential-and-poor-prognosis-in-patients-with-resected-lung-cancer
#8
Takatoshi Fujishita, Tatsuro Okamoto, Takaki Akamine, Shinkichi Takamori, Kazuki Takada, Masakazu Katsura, Goji Toyokawa, Fumihiro Shoji, Mototsugu Shimokawa, Yoshinao Oda, Yusaku Nakabeppu, Yoshihiko Maehara
OBJECTIVES: The oxidized purine nucleoside triphosphatase, mutT homolog 1 (MTH1), physiologically sanitizes 8-oxo-dGTP in the nucleotide pool. Previous studies indicated that MTH1 is associated with tumor proliferation and invasion in non-small cell lung cancer (NSCLC) cell lines; however, the role of MTH1 in patients with NSCLC remains unclear. MATERIALS AND METHODS: Two patient cohorts that underwent surgery for NSCLC in our institution were investigated retrospectively...
July 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28574988/the-differing-influence-of-several-factors-on-the-development-of-fatty-liver-with-elevation-of-liver-enzymes-between-genders-with-metabolic-syndrome-a-cross-sectional-study
#9
Masahiro Sogabe, Toshiya Okahisa, Masahiko Nakasono, Hiroshi Fukuno, Yoshihiko Miyamoto, Yasuyuki Okada, Jun Okazaki, Jinsei Miyoshi, Tetsu Tomonari, Tatsuya Taniguchi, Takahiro Goji, Shinji Kitamura, Hiroshi Miyamoto, Naoki Muguruma, Tetsuji Takayama
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is known to be strongly associated with obesity, visceral fat, metabolic syndrome (MS), lifestyle, and lifestyle-related diseases in both males and females. However, the prevalence of NAFLD, MS, and clinical backgrounds is different between males and females. OBJECTIVE: We conducted a cross-sectional study to examine the differing influence of lifestyle-related factors and visceral fat on fatty liver (FL) with elevation of liver enzymes between males and females with MS...
2017: PloS One
https://www.readbyqxmd.com/read/28447344/short-term-treatments-with-high-co2-and-low-o2-concentrations-on-quality-of-fresh-goji-berries-lycium-barbarum-l-during-cold-storage
#10
Mina Kafkaletou, Miltiadis V Christopoulos, Eleni Tsantili
BACKGROUND: Goji berries (Lycium barbarum L.) are functional fruits, but usually disposed to markets as dried. The aim, here, was to investigate the storability of fresh goji berries treated with high CO2 and low O2 concentrations before air storage at 1 °C for 21 d. RESULTS: Berries harvested without stems were exposed to air (controls) or treated for 2 d at 1 °C with the following controlled atmosphere (CA) treatments: 21% O2 + 0% CO2 (21 + 0), 5% O2 + 15% CO2 (5 + 15), 10% O2 + 10% CO2 (10 + 10) and 20% O2 + 20% CO2 (20 + 20)...
April 26, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28424747/association-between-optic-nerve-head-microcirculation-and-macular-ganglion-cell-complex-thickness-in-eyes-with-untreated-normal-tension-glaucoma-and-a-hemifield-defect
#11
Ayako Anraku, Kyoko Ishida, Nobuko Enomoto, Seiji Takagi, Hiroyuki Ito, Asuka Takeyama, Fumihiko Yagi, Goji Tomita
Purpose. We evaluated the association between optic nerve head (ONH) microcirculation and macular ganglion cell complex (mGCC) thickness in patients with untreated normal tension glaucoma (NTG) and a hemifield defect. Methods. The medical records of 47 patients with untreated NTG were retrospectively reviewed. Laser speckle flowgraphy was used to obtain mean blur rate (MBR), a relative measure of blood flow. Average total deviation (TD), mGCC, and the circumpapillary retinal nerve fiber layer (cpRNFL) thickness were also analyzed...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28420309/a-proton-magnetic-resonance-spectroscopic-study-in-autism-spectrum-disorder-using-a-3-tesla-clinical-magnetic-resonance-imaging-mri-system-the-anterior-cingulate-cortex-and-the-left-cerebellum
#12
Hiromichi Ito, Kenji Mori, Masafumi Harada, Sonoka Hisaoka, Yoshihiro Toda, Tatsuo Mori, Aya Goji, Yoko Abe, Masahito Miyazaki, Shoji Kagami
The pathophysiology of autism spectrum disorder (ASD) is not fully understood. We used proton magnetic resonance spectroscopy to investigate metabolite concentration ratios in the anterior cingulate cortex and left cerebellum in ASD. In the ACC and left cerebellum studies, the ASD group and intelligence quotient- and age-matched control group consisted of 112 and 114 subjects and 65 and 45 subjects, respectively. In the ASD group, γ-aminobutyric acid (GABA)+/ creatine/phosphocreatine (Cr) was significantly decreased in the anterior cingulate cortex, and glutamate (Glu)/Cr was significantly increased and GABA+/Cr was significantly decreased in the left cerebellum compared to those in the control group...
July 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28411517/pre-and-post-surgical-psychiatric-assessments-and-intervention-by-major-epilepsy-centers-in-japan-nationwide-survey
#13
Hiroko Goji, Toshihiko Fukuchi, Kousuke Kanemoto
BACKGROUND: Although psychiatric issues following epilepsy surgery are now widely recognized as a major problem, actual awareness of these issues by epilepsy centers remains to be elucidated. This is the first known report regarding the use of psychiatric assessments and interventions by epilepsy centers throughout Japan. PARTICIPANTS AND METHODS: At the beginning of 2016, we sent a questionnaire regarding psychiatric assessments performed before and after epilepsy surgery, psychiatric intervention after surgery, and future plans for dealing with psychiatric issues in relation to epilepsy surgery, which consisted of a total of 24 items, to all members of the Japan Epilepsy Center Association (JEPICA)...
May 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28407908/stability-of-goji-bioactives-during-extrusion-cooking-process
#14
Agnieszka Kosińska-Cagnazzo, Dimitri Bocquel, Isabelle Marmillod, Wilfried Andlauer
Due to the increasing popularity of goji berries, efforts are made to enlarge the offer of goji containing foods. In this study, rice flour based extrudates enriched with goji berries were investigated. The extrusion was performed using a twin screw extruder with constant feed moisture and screw speed. Raw mixtures as well as extruded products obtained were analysed in order to determine antioxidant activity and contents of rutin, zeaxanthin dipalmitate and 2-O-β-d-glucopyranosyl-l-ascorbic acid. The antioxidant activity of goji extrudates was boosted up to 20times compared to the extrudates without any addition...
September 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28407907/the-effects-of-postharvest-application-of-lecithin-to-improve-storage-potential-and-quality-of-fresh-goji-lycium-barbarum-l-berries
#15
Mushtaque Ahmed Jatoi, Slaven Jurić, Rajko Vidrih, Marko Vinceković, Marko Vuković, Tomislav Jemrić
To enhance storage life and post-storage quality of fresh goji berries, three treatments with lecithin (1, 5, 10g·L(-1)) and two storage times (8, 16days) were evaluated. The significant effects on the physiological and biochemical parameters were varied. 1g·L(-1) lecithin showed its main effects after 8days of storage by reduction in total weight loss and decay, SSC/TA ratio (also at 16days), and chlorophyll content and with highest scores of sensory attributes (also at 16days). 5g·L(-1) lecithin showed its main effects after 16days of storage: highest SSC, highest TA (also at 8days), highest TPC, only significant reduction in DPPH antioxidant activity, and highest total flavonoid content...
September 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28394267/calabrian-goji-vs-chinese-goji-a-comparative-study-on-biological-properties
#16
Mariarosa Ruffo, Ortensia Ilaria Parisi, Fabio Amone, Rocco Malivindi, Domenico Gorgoglione, Filomena De Biasio, Luca Scrivano, Vincenzo Pezzi, Francesco Puoci
Lycium barbarum (Goji) fruits are mainly cultivated in northwestern China and are well known for their beneficial and healthy effects. In this work, the biological and functional properties of Calabrian Goji extract, obtained from Goji berries cultivated in the Sibari Plain (in the Italian region of Calabria), were demonstrated. In order to evaluate the use of this extract as a food supplement for cognitive and mental disorders, the quantification of Carotenoids as Zeaxanthin equivalents was made. The antioxidant activity was investigated by evaluating the scavenging properties against 2,2'-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-Azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals and by performing the ORAC (Oxygen Radical Absorbance Capacity) assay...
April 10, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28347301/does-social-distinction-contribute-to-socioeconomic-inequalities-in-diet-the-case-of-superfoods-consumption
#17
Joost Oude Groeniger, Frank J van Lenthe, Mariëlle A Beenackers, Carlijn B M Kamphuis
BACKGROUND: The key mechanisms underlying socioeconomic inequalities in dietary intake are still poorly understood, hampering the development of interventions. An important, but sparsely mentioned mechanism is that of 'social distinction', whereby those in a higher socioeconomic position adopt dietary patterns by which they can distinguish themselves from lower socioeconomic groups. We investigated the importance of distinction as a mechanism, by testing the socioeconomic gradient in the consumption of so-called 'superfoods' and the contribution of a well-established indicator of distinction, cultural participation...
March 27, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28321069/cerebral-salt-wasting-syndrome-and-inappropriate-antidiuretic-hormone-syndrome-after-subarachnoid-hemorrhaging
#18
Hanako Nakajima, Hiroshi Okada, Kazuki Hirose, Toru Murakami, Yayoi Shiotsu, Mayuko Kadono, Mamoru Inoue, Goji Hasegawa
Hyponatremia is a common finding after subarachnoid hemorrhaging (SAH) and can be caused by either cerebral salt-wasting syndrome (CSWS) or syndrome of inappropriate antidiuretic hormone (SIADH). Distinguishing between these two entities can be difficult because they have similar manifestations, including hyponatremia, serum hypo-osmolality, and high urine osmolality. We herein report the case of a 60-year-old man who suffered from SAH complicated by hyponatremia. During his initial hospitalization, he was diagnosed with CSWS...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28270110/comparative-genomics-of-enterococcus-spp-isolated-from-bovine-feces
#19
Alicia G Beukers, Rahat Zaheer, Noriko Goji, Kingsley K Amoako, Alexandre V Chaves, Michael P Ward, Tim A McAllister
BACKGROUND: Enterococcus is ubiquitous in nature and is a commensal of both the bovine and human gastrointestinal (GI) tract. It is also associated with clinical infections in humans. Subtherapeutic administration of antibiotics to cattle selects for antibiotic resistant enterococci in the bovine GI tract. Antibiotic resistance genes (ARGs) may be present in enterococci following antibiotic use in cattle. If located on mobile genetic elements (MGEs) their dissemination between Enterococcus species and to pathogenic bacteria may be promoted, reducing the efficacy of antibiotics...
March 8, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28268000/speciation-analysis-and-bioaccessibility-evaluation-of-trace-elements-in-goji-berries-lycium-barbarum-l
#20
Justyna Wojcieszek, Piotr Kwiatkowski, Lena Ruzik
Goji berries (Lycium Barbarum, L.) are known for their nutritional potential as a great source of trace metals (e.g., copper, zinc and manganese) which are present in the form of highly bioaccessible compounds. In order to assess the bioaccessibility of trace elements and to identify compounds responsible for better bioaccessibility of copper and zinc, an in vitro simulation of gastrointestinal digestion was used in this study. The total content of trace metals was evaluated using sample digestion followed by inductively coupled plasma mass spectrometry...
April 7, 2017: Journal of Chromatography. A
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