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Kasım Demir

Ahmet Bal, Yucel Gonul, Omer Hazman, Ahmet Kocak, Mehmet Fatih Bozkurt, Sezgin Yilmaz, Serdar Kokulu, Oya Oruc, Kasim Demir
BACKGROUND: The aim of this study was to investigate the possible protective effect of interleukin 18-binding protein (IL-18BP) on ischemia-reperfusion (I/R)-induced liver injury in experimental rat models. Liver is one of the most affected organs from I/R process. IL-18 is an important proinflammatory cytokine, which may induce some events such as production of reactive oxygen substances and release of various cytokines. IL-18BP acts as an inhibitor of IL-18. The relationship between IL-18 and IL-18BP has an important place in inflammatory process...
March 2016: Journal of Surgical Research
Akif Acay, Kasim Demir, Gulsah Asik, Havva Tunay, Gursel Acarturk
OBJECTIVE: To examine the occurrence frequency of auto-antibodies and autoimmune diseases in patients with chronic hepatitis B or C. METHODS: A total of 67 patients diagnosed with chronic hepatitis B and 77 patients diagnosed with chronic hepatitis C infection based on HBs Ag, Anti HCV, HBe Ag, Anti HBe Ag, HBV DNA, HCV RNA, liver ultrasound, and liver biopsy results as well as 48 healthy individuals were included in this study. ANA, anti dsDNA, anti LKM, Anti-SMA, AMA, C-ANCA, P-ANCA, anti-SSA, anti-SSB, anti-Scl-70, anti Jo-1, anti-U1snRNP, anti-centromere, anti-Jo-1, anti tpo, and anti tg were studied in all individuals in each study group...
January 2015: Pakistan Journal of Medical Sciences Quarterly
Akif Acay, Memnune Sena Ulu, Ahmet Ahsen, Gulay Ozkececi, Kasim Demir, Ufuk Ozuguz, Seref Yuksel, Gursel Acarturk
BACKGROUND AND OBJECTIVE: Numerous inflammatory and innate immune pathways are involved in atherogenesis. We aimed to investigate the atherogenic index and other lipid parameters in individuals with familial Mediterranean fever (FMF), as a predictor of atherosclerosis. MATERIALS AND METHODS: A total of 60 patients with FMF and 60 healthy age- and sex-matched controls were included in this study. The patients with acute infection, chronic metabolic and rheumatic diseases, use of drugs other than colchicine and smoking history were excluded...
2014: Medicina
Sena Memnune Ulu, Ahmet Ahsen, Önder Akcı, Fatima Yaman, Kasım Demir, Gökhan Yaman, Şeref Yüksel, Gürsel Acartürk
OBJECTIVE: The lack of nocturnal decline in blood pressure (BP) is associated with an increase in cardiovascular events. Restless leg syndrome (RLS) is an uncomfortable feeling in which the patient wants to budge the legs with ache in the legs. RLS also increases the hypertension and cardiovascular risk. In this study, we aimed to evaluate the relationship between dipping and non-dipping blood pressure patterns with RLS and its severity. METHODS: Two hundred patients who had 24-hour ambulatory blood pressure monitoring (ABPM) were enrolled into this cross-sectional study...
April 2015: Anatolian Journal of Cardiology
Mahmut Sunnetcioglu, Sevdegul Karadas, Mehmet Aslan, Mehmet Resat Ceylan, Halit Demir, Mehmet Resit Oncu, Mustafa Kasım Karahocagil, Aysel Sunnetcioglu, Cenk Aypak
BACKGROUND: Adenosine deaminase (ADA) activity has been discovered in several inflammatory conditions; however, there are no data associated with cutaneous anthrax. The aim of this study was to investigate serum ADA activity in patients with cutaneous anthrax. MATERIAL AND METHODS: Sixteen patients with cutaneous anthrax and 17 healthy controls were enrolled. We measured ADA activity; peripheral blood leukocyte, lymphocyte, neutrophil, and monocyte counts; erythrocyte sedimentation rate; and C reactive protein levels...
2014: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Sena Memnune Ulu, Mustafa Dogan, Ahmet Ahsen, Abdullah Altug, Kasım Demir, Gürsel Acartürk, Sibel Inan
INTRODUCTION: Diabetic retinopathy (DR) is the most common complication and cause of visual impairment in diabetes patients. The pathogenesis is not fully understood, but several studies have suggested that inflammation plays an important role. The neutrophil-to-lymphocyte ratio (NLR) was defined as a novel potential marker to determine inflammation. We aimed to evaluate the relationship between DR and inflammation by using NLR. PATIENTS AND METHODS: The study was included 58 patients diagnosed with type 2 diabetes mellitus...
November 2013: Diabetes Technology & Therapeutics
Ahmet Ahsen, Memnune Sena Ulu, Seref Yuksel, Kasım Demir, Mukremin Uysal, Mujgan Erdogan, Gursel Acarturk
Familial Mediterranean fever (FMF), which is an autosomal recessive disease, is characterised by recurrent febrile episodes in association with peritonitis, pleuritis and arthritis and has ongoing subclinical inflammation during attack-free period. In this study, we aimed to investigate the relationship between FMF with neutrophil-to-lymphocyte ratio (NLR), which is determined in many chronic inflammations as a new potential inflammatory mediator. We included 62 patients and 41 healthy subjects who were similar in terms of age and sex...
December 2013: Inflammation
Cengiz Demir, Mustafa Kasim Karahocagil, Ramazan Esen, Murat Atmaca, Hayriye Gönüllü, Hayrettin Akdeniz
BACKGROUND: Brucellosis can mimic various multisytem diseases, showing wide clinical polymorphism that frequently leads to misdiagnosis and treatment delay, further increasing the complication rates. In this study, we aimed to examine bone marrow biopsy findings in brucellosis cases presenting with hematologic abnormalities. METHODS: Forty-eight brucellosis cases were prospectively investigated. Complaints and physical examination findings of patients were recorded...
June 2012: Chinese Medical Journal
Dicle Hazirolan, Gulten Sungur, Necati Demir, Remzi Kasim, Sunay Duman
PURPOSE: To describe the clinical features of an atypical form of viral retinitis in immunocompetent patients. METHODS: This was a retrospective noncomparative case series. The charts of 8 patients diagnosed with and treated for focal posterior viral retinitis were reviewed. Clinical and demographic features were evaluated. All the patients had extensive laboratory tests, fundus fluorescein angiography, optical coherence tomography of macula, and polymerase chain reaction of vitreous...
September 2010: European Journal of Ophthalmology
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