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Osteoporosis elderly

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https://www.readbyqxmd.com/read/28634415/force-induced-increased-osteogenesis-enables-accelerated-orthodontic-tooth-movement-in-ovariectomized-rats
#1
Qinggang Dai, Siru Zhou, Peng Zhang, Xuhui Ma, Nayong Ha, Xiao Yang, Zhifeng Yu, Bing Fang, Lingyong Jiang
As the number of elderly orthodontic patients increases, the impact of postmenopausal osteoporosis on orthodontic tooth movement (OTM) has attracted a great deal of attention because OTM relies on alveolar bone remodeling. The question of whether OTM causes subsequent alveolar bone loss and is harmful to alveolar bone health under osteoporotic conditions remains to be answered. The present study aimed to clarify the influences of OTM on alveolar bone in osteoporotic rats. OTM was accelerated in ovariectomized (OVX) rats as a result of increased bone resorption in the pressure area...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28632666/change-in-calcaneal-bone-strength-in-long-term-care-residents-treated-with-low-intensity-pulsed-ultrasound
#2
Hiroyasu Okuizumi, Kiyoshi Koyano, Kazuya Kurosawa, Naoto Kamide, Ayako Soyano
OBJECTIVE: We examined the effect of low-intensity pulsed ultrasound (LIPUS) on bone strength in osteoporotic elderly residents. MATERIALS AND METHODS: This was a randomized controlled trial. Elderly residents with osteoporosis in a long-term care facility were treated with LIPUS (oscillation frequency 100 KHz) that involved treatment of the heel bone for 2 minutes a day. The selection of the treated heel was decided randomly with a personal computer. The heel bone mineral density before and after treatment was measured by calcaneal quantitative ultrasound (GE-1000 Express)...
July 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28630761/partial-proximal-tibia-fractures
#3
Michael J Raschke, Christoph Kittl, Christoph Domnick
Partial tibial plateau fractures may occur as a consequence of either valgus or varus trauma combined with a rotational and axial compression component.High-energy trauma may result in a more complex and multi-fragmented fracture pattern, which occurs predominantly in young people. Conversely, a low-energy mechanism may lead to a pure depression fracture in the older population with weaker bone density.Pre-operative classification of these fractures, by Müller AO, Schatzker or novel CT-based methods, helps to understand the fracture pattern and choose the surgical approach and treatment strategy in accordance with estimated bone mineral density and the individual history of each patient...
May 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28620304/pu-erh-tea-extract-ameliorates-ovariectomy-induced-osteoporosis-in-rats-and-suppresses-osteoclastogenesis-in-vitro
#4
Titi Liu, Shihua Ding, Dan Yin, Xiangdan Cuan, Chuanqi Xie, Huanhuan Xu, Xuanjun Wang, Jun Sheng
Background and Objective: Tea drinking is associated with positive effects on bone health and may protect against osteoporosis, especially in elderly women. Pu-erh tea has many beneficial effects on human health; however, whether Pu-erh tea has anti-osteoporotic potential remains unclear. Thus, we investigated the effects of Pu-erh tea extract (PTE) on ovariectomy-induced osteoporosis in rats and on osteoclastogenesis in vitro. Methods: Female Wistar rats were divided into six groups: the sham, model, and Xian-Ling-Gu-Bao capsule (XLGB) groups, and the low-, medium-, and high-dose PTE groups...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28593447/predictors-of-near-term-fracture-in-osteoporotic-women-aged-%C3%A2-65%C3%A2-years-based-on-data-from-the-study-of-osteoporotic-fractures
#5
D Weycker, J Edelsberg, R Barron, M Atwood, G Oster, D B Crittenden, A Grauer
Using data from the Study of Osteoporotic Fractures (SOF), several clinical characteristics predictive of near-term (1-year) risk of hip and non-vertebral fracture among elderly osteoporotic women were identified, and a subset of those for hip fracture was incorporated into a risk assessment tool. Additional research is needed to validate study findings. INTRODUCTION: While several risk factors are known to contribute to long-term fracture risk in women with osteoporosis, factors predicting fracture risk over a shorter time horizon, such as over a 1-year period, are less well-established...
June 7, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28592102/-assessment-of-comprehensive-nutritional-status-and-eating-behavior-among-311-middle-aged-and-aged-women-with-osteoporosis-in-chengdu
#6
R P Zhao, W Z Wang, G P Cheng, H J Zhang, F M Zhou, Y Y Li, C Wu, L Q Yang, G Zeng
Objective: To investigate the comprehensive nutritional status and diet behavior of middle aged and elderly women with osteoporosis, and thereby to explore the relationship between diet behavior and comprehensive nutritional status. Methods: 311 middle-aged and elderly women with osteoporosis in Chengdu were included in this study. Mini Nutritional Assessment (MNA) was applied to assess their comprehensive nutritional status. Information of social-demographic characteristics and diet behavior (about meals, snacks and water drinking, etc...
June 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28591341/the-effect-of-frax-on-the-prediction-of-osteoporotic-fractures-in-urban-middle-aged-and-elderly-healthy-chinese-adults
#7
Jun Wang, Xuejun Wang, Zhen Fang, Nanjia Lu, Liyuan Han
OBJECTIVE: We aimed to analyze the applicability of a fracture risk assessment tool for the prediction of osteoporotic fractures in middle-aged and elderly healthy Chinese adults. METHODS: A standard questionnaire was administered, and bone mineral density was measured in residents visiting the Dongliu Street Community Health Service Center. Paired t-tests were used to compare the FRAX-based probabilities of fractures estimated with and without consideration of bone mineral density...
May 2017: Clinics
https://www.readbyqxmd.com/read/28591176/moxibustion-treatment-for-primary-osteoporosis-a-systematic-review-of-randomized-controlled-trials
#8
Fanping Xu, Minghua Huang, Yi Jin, Qingzhe Kong, Zhongmin Lei, Xu Wei
Primary osteoporosis (POP) has a serious impact on quality of life for middle-aged and elderly, which particularly increase the risk of fracture. We conducted the systematic review to evaluate the effects of moxibustion for POP in randomized controlled trials (RCTs).Eight databases were searched from their inception to July 30, 2016. The RCTs reporting the moxibustion as a monotherapy or in combination with conventional therapy for POP were enrolled. The outcomes might be fracture incidence, quality of life, clinical symptoms, death attributed to osteoporosis, adverse effect, bone mineral density (BMD), and biochemical indicators...
2017: PloS One
https://www.readbyqxmd.com/read/28587540/intertan-nail-versus-proximal-femoral-nail-antirotation-asia-for-intertrochanteric-femur-fractures-in-elderly-patients-with-primary-osteoporosis
#9
Hui Zhang, Xianshang Zeng, Nan Zhang, Dan Zeng, Ping Xu, Lili Zhang, Deng Chen, Weiguang Yu, Xinchao Zhang
Objectives To compare the long-term functional and radiographic outcomes of the proximal femoral nail antirotation-Asia (PFNA-II) and INTERTAN nail (IT) in the management of intertrochanteric femoral fractures (IFFs) (AO/OTA Type 31A1.1-A2.3) in elderly patients with primary osteoporosis. Methods A retrospective comparative study was performed in our institution. From January 2009 to March 2012, 243 patients with osteoporosis (243 hips) with IFFs (AO/OTA Type 3.1A1.1-A2.3) underwent repair with either a PFNA-II or IT...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28587413/decreased-trabecular-bone-deterioration-of-proximal-tibiae-and-lumbar-vertebrae-in-postmenopausal-women-with-osteoarthritis
#10
Zhenhua Yin, Wei Wang, Jian Han, Ke Chen, Jianjun Ma
Osteoporosis and osteoarthritis (OA) are two common age-related skeletal disorders, which are associated with substantial morbidity and disability, particularly among elderly women. The present study was performed to investigate the trabecular bone deterioration of proximal tibiae and lumbar vertebrae in postmenopausal women with OA. The results demonstrated that the histomorphometric section of trabecular bone below the growth plate was markedly different between the healthy control and OA group. However, the loss of trabecular bone underneath the growth plate in the healthy control group was significantly worse than that of the OA group...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28567345/dementia-and-osteoporosis-in-a-geriatric-population-is-there-a-common-link
#11
Candice L Downey, Adam Young, Emily F Burton, Simon M Graham, Robert J Macfarlane, Eva-Maria Tsapakis, Eleftherios Tsiridis
AIM: To determine the existence of a common pathological link between dementia and osteoporosis through reviewing the current evidence base. METHODS: This paper reviews the current literature on osteoporosis and dementia in order to ascertain evidence of a common predisposing aetiology. A literature search of Ovid MED-LINE (1950 to June 2016) was conducted. The keywords "osteoporosis", "osteoporotic fracture", "dementia" and "Alzheimer's disease" (AD) were used to determine the theoretical links with the most significant evidence base behind them...
May 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28549357/-hip-osteosynthesis-with-im-nail-lateral-decubitus-without-fracture-table
#12
V H Aguirre-Rodríguez, G Inzunza-Enríquez, O Bibiano-Escalante, F J Martínez-Ruiz, F S Valero-González
BACKGROUND: Hip fractures have increased in the last decades, mainly in elderly patients with osteoporosis. The incidence becomes in some countries up to 250 thousand new cases per year, generating millions for health systems costs, so it should be considered a public health problem. They are treated in supine position, with a fracture table, through a lateral approach. However, it is important to know that there are other techniques, which can dispense a table of fractures and in a different position...
November 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28537325/association-of-protein-intake-with-bone-mineral-density-and-bone-mineral-content-among-elderly-women-the-ostpre-fracture-prevention-study
#13
M Isanejad, J Sirola, J Mursu, H Kröger, M Tuppurainen, A T Erkkilä
It has been hypothesized that high protein intakes are associated with lower bone mineral content (BMC). Previous studies yield conflicting results and thus far no studies have undertaken the interaction of body mass index (BMI) and physical activity with protein intakes in relation to BMC and bone mineral density (BMD). OBJECTIVE: To evaluate the associations of dietary total protein (TP), animal protein (AP) and plant protein (PP) intakes with BMC and BMD and their changes. We tested also the interactions of protein intake with, obesity (BMI ≤30 vs...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28536737/examining-the-treatment-gap-and-risk-of-subsequent-fractures-among-females-with-a-fragility-fracture-in-the-us-medicare-population
#14
A Keshishian, N Boytsov, R Burge, K Krohn, L Lombard, X Zhang, L Xie, O Baser
Our aim was to evaluate the gap in osteoporosis treatment and the impact of osteoporosis treatment on subsequent fragility fractures. We found osteoporosis medication use lowered risk of subsequent fractures by 21% and that black race, higher CCI scores, dementia, and kidney diseases reduced the likelihood of osteoporosis medication use. INTRODUCTION: The goal of this study was to evaluate the predictors of osteoporosis medication use and compare the risk of fragility fractures within 1 year of a fragility fracture between osteoporosis treated and untreated women...
May 23, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28534471/management-of-acetabular-fractures-in-the-geriatric-patient
#15
Marc Hanschen, Sebastian Pesch, Stefan Huber-Wagner, Peter Biberthaler
INTRODUCTION: Open reduction and internal fixation (ORIF) is standard care for most acetabular fractures. With increasing numbers of acetabular fractures in the elderly, the risk of revision surgery and conversion to total hip replacement (THR) is increasing. Alarmingly, about 20-25% of acetabular fractures in the elderly following ORIF needed revision and conversion to delayed THR. METHODS: Recently, prognostic factors have been identified, which correlate with an increased risk of worse outcomes following ORIF of acetabular fractures in the elderly patient...
2017: SICOT-J
https://www.readbyqxmd.com/read/28532056/stiff-porous-scaffolds-from-magnetized-alumina-particles-aligned-by-magnetic-freeze-casting
#16
Michael B Frank, Steven E Naleway, Tsuk Haroush, Chin-Hung Liu, Sze Hei Siu, Jerry Ng, Ivan Torres, Ali Ismail, Keyur Karandikar, Michael M Porter, Olivia A Graeve, Joanna McKittrick
Bone consists of a hard mineral phase and a compliant biopolymer phase resulting in a composite material that is both lightweight and strong. Osteoporosis that degrades spongy bone preferentially over time leads to bone brittleness in the elderly. A porous ceramic material that can mimic spongy bone for a one-time implant provides a potential solution for the future needs of an aging population. Scaffolds made by magnetic freeze casting resemble the aligned porosity of spongy bone. A magnetic field applied throughout freezing induces particle chaining and alignment of lamellae structures between growing ice crystals...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28523260/combination-therapy-of-raloxifene-and-alendronate-for-treatment-of-osteoporosis-in-elderly-women
#17
Mi Jung Um, Eun A Cho, Hyuk Jung
OBJECTIVES: To evaluate and compare the efficacy and safety of the combination of raloxifene and alendronate with those of monotherapies in elderly women with osteoporosis. METHODS: Sixty-two postmenopausal women (mean age 63.5 ± 0.5 years) attending gynecologic osteoporosis clinics with established osteoporosis were randomly allocated to one of four treatment groups and monitored for 3 years. All patients enrolled in this study, including those in the control group (n = 14), received 1...
April 2017: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/28511733/similarities-and-interactions-between-the-ageing-process-and-high-chronic-intake-of-added-sugars
#18
Eva Gatineau, Sergio Polakof, Dominique Dardevet, Laurent Mosoni
In our societies, the proportions of elderly people and of obese individuals are increasing. Both factors are associated with high health-related costs. During obesity, many authors suggest that it is a high chronic intake of added sugars (HCIAS) that triggers the shift towards pathology. However, the majority of studies were performed in young subjects and only a few were interested in the interaction with the ageing process. Our purpose was to discuss the metabolic effects of HCIAS, compare with the effects of ageing, and evaluate how deleterious the combined action of HCIAS and ageing could be...
May 17, 2017: Nutrition Research Reviews
https://www.readbyqxmd.com/read/28507975/charcot-fracture-in-the-calcaneus-after-total-knee-arthroplasty-a-case-report
#19
Hirokazu Takai, Katsuhiko Kiyota, Nobutake Nakane, Tomoki Takahashi
INTRODUCTION: Only a few reports have described calcaneus fractures after total knee arthroplasty (TKA). Therefore, in this report, we describe a case of calcaneal avulsion fracture that occurred 5 weeks after a TKA in a relatively young male patient with syphilis. CASE REPORT: A 63-year-old man with syphilis had Charcot joint of the right knee. The patient developed severe varus deformity and contracture and experienced severe pain in the knee. TKA was performed to alleviate the pain and improve the patient's gait...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28469357/healthcare-maintenance-in-elderly-patients-with-inflammatory-bowel-disease
#20
REVIEW
Manish P Shrestha, Joannie Ruel, Sasha Taleban
The increasing number of older patients (age ≥60 years) with inflammatory bowel disease (IBD) highlights the importance of healthcare maintenance in this vulnerable population. Older IBD patients are more susceptible and have higher rates of many disease- and treatment-related adverse effects. Compared to younger IBD patients, older patients are at increased risk for infection, malignancy, bone disease, eye disease, malnutrition and thrombotic complications. Preventive strategies in the elderly differ from those in younger adults and are imperative...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
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