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Osteoporosis elderly

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https://www.readbyqxmd.com/read/29774416/restoration-of-proximal-periprosthetic-bone-loss-by-denosumab-in-cementless-total-hip-arthroplasty
#1
Satoshi Nagoya, Kenji Tateda, Shunichiro Okazaki, Ima Kosukegawa, Junya Shimizu, Toshihiko Yamashita
Denosumab contributed to the restoration of proximal periprosthetic bone loss around the femoral stem that were measured using a DEXA, especially in zone 7, at 1 year after cementless THA in elderly osteoporotic patients. INTRODUCTION: Although bone quality is an important issue in elderly osteoporotic patients who underwent total hip arthroplasty (THA) with a cementless stem, periprosthetic bone mineral density (BMD) in the proximal femur has been reported to be decreased by 15-40% postoperatively...
May 17, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29774199/malignant-metastasis-misdiagnosed-as-osteoporotic-compression-fracture-a-case-report
#2
Seul Gi Kim, Chang Il Ju, Hui Sun Wang, Seok Won Kim
In cases of vertebral collapse after a trivial injury in elderly patients with severe osteoporosis, it can be a diagnostic challenge to determine whether the cause is a benign compression fracture or malignant metastasis. A 78-year-old male patient was referred to the emergency department for the evaluation of weakness of the left lower limb. He had undergone percutaneous vertebroplasty four months earlier after being diagnosed with L3 osteoporotic compression fracture. He was treated with foraminotomy at the L3-4 level after being diagnosed with foraminal stenosis two months earlier at a spine clinic...
April 2018: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29764380/osteoporosis-diabetes-and-hypertension-are-major-risk-factors-for-mortality-in-older-adults-an-intermediate-report-on-a-prospective-survey-of-1467-community-dwelling-elderly-healthy-pensioners-in-switzerland
#3
Jean-Pierre Gutzwiller, Jean-Pierre Richterich, Zeno Stanga, Urs E Nydegger, Lorenz Risch, Martin Risch
BACKGROUND: Osteoporosis is an important morbidity factor for ageing populations in developed countries. However, compared to the amount of information available on diabetes and cardiovascular disease, little is known about the direct impact of osteoporosis on general mortality in older age. METHODS: We obtained data from a prospective population-based cohort of pensioners from the SENIORLAB study who were subjectively healthy. The inclusion criteria were an age of at least 60 years and Swiss residence...
May 15, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29751644/protective-effects-of-selected-botanical-agents-on-bone
#4
REVIEW
James Jam Jolly, Kok-Yong Chin, Ekram Alias, Kien Hui Chua, Ima Nirwana Soelaiman
Osteoporosis is a serious health problem affecting more than 200 million elderly people worldwide. The early symptoms of this disease are hardly detectable. It causes progressive bone loss, which ultimately renders the patients susceptible to fractures. Osteoporosis must be prevented because the associated fragility fractures result in high morbidity, mortality, and healthcare costs. Many plants used in herbal medicine contain bioactive compounds possessing skeletal protective effects. This paper explores the anti-osteoporotic properties of selected herbal plants, including their actions on osteoblasts (bone forming cells), osteoclasts (bone resorbing cells), and bone remodelling...
May 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29748140/bone-microarchitecture-of-the-tibial-plateau-in-skeletal-health-and-osteoporosis
#5
Matthias Krause, Jan Hubert, Simon Deymann, Alexander Hapfelmeier, Birgit Wulff, Andreas Petersik, Klaus Püschel, Michael Amling, Thelonius Hawellek, Karl-Heinz Frosch
BACKGROUND: Impaired bone structure poses a challenge for the treatment of osteoporotic tibial plateau fractures. As knowledge of region-specific structural bone alterations is a prerequisite to achieving successful long-term fixation, the aim of the current study was to characterize tibial plateau bone structure in patients with osteoporosis and the elderly. METHODS: Histomorphometric parameters were assessed by high-resolution peripheral quantitative computed tomography (HR-pQCT) in 21 proximal tibiae from females with postmenopausal osteoporosis (mean age: 84...
May 7, 2018: Knee
https://www.readbyqxmd.com/read/29746627/higher-dietary-glycemic-index-and-glycemic-load-values-increase-the-risk-of-osteoporotic-fracture-in-the-prevenci%C3%A3-n-con-dieta-mediterr%C3%A3-nea-predimed-reus-trial
#6
Jesús Francisco García-Gavilán, Mònica Bulló, Lucia Camacho-Barcia, Nuria Rosique-Esteban, Pablo Hernández-Alonso, Josep Basora, Miguel Angel Martínez-González, Ramón Estruch, Montserrat Fitó, Jordi Salas-Salvadó
Background: High glucose and insulin concentrations seem to have a negative impact on bone health. However, the relation between the dietary glycemic index (DGI) and the dietary glycemic load (DGL), which has proved to be effective at modulating blood glucose concentrations after carbohydrate consumption, has yet to be explored in relation to bone health. Objective: The aim of the study was to examine the associations between the DGI or DGL and the risk of osteoporotic-related fractures in an elderly Mediterranean population...
May 9, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29740667/benefits-and-safety-of-dietary-protein-for-bone-health-an-expert-consensus-paper-endorsed-by-the-european-society-for-clinical-and-economical-aspects-of-osteopororosis-osteoarthritis-and-musculoskeletal-diseases-and-by-the-international-osteoporosis-foundation
#7
REVIEW
R Rizzoli, E Biver, J-P Bonjour, V Coxam, D Goltzman, J A Kanis, J Lappe, L Rejnmark, S Sahni, C Weaver, H Weiler, J-Y Reginster
A summary of systematic reviews and meta-analyses addressing the benefits and risks of dietary protein intakes for bone health in adults suggests that dietary protein levels even above the current RDA may be beneficial in reducing bone loss and hip fracture risk, provided calcium intakes are adequate. Several systematic reviews and meta-analyses have addressed the benefits and risks of dietary protein intakes for bone health in adults. This narrative review of the literature summarizes and synthesizes recent systematic reviews and meta-analyses and highlights key messages...
May 8, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29738597/fall-risk-assessment-metrics-for-elderly-patients-with-hip-fractures
#8
Christos Th Vottis, Evanthia Mitsiokapa, Vasilios G Igoumenou, Panayiotis D Megaloikonomos, Ioannis P Galanopoulos, George Georgoudis, Panayiotis Koulouvaris, Panayiotis J Papagelopoulos, Andreas F Mavrogenis
The most common surgery performed by orthopedic surgeons likely involves that for hip fractures. The incidence of hip fractures is anticipated to rise in the coming decades. Hip fractures most commonly occur in elderly women with osteoporosis after a fall from standing position. In an effort to reduce the incidence, improve the postoperative care, and accelerate the rehabilitation of hip fractures, it is important to evaluate the fall risk of these patients, as it is an objective indication of their level of physical activity...
May 8, 2018: Orthopedics
https://www.readbyqxmd.com/read/29737744/-clinical-analysis-of-adult-spontaneous-cerebrospinal-fluid-rhinorrhea
#9
Zheng Jie Zhu, Lan Cheng, Jun Yang, Qi Huang, Guo Zhen Meng, Rong Ping Cao
OBJECTIVES: To discuss the clinical characteristics, diagnosis and treatment of adult spontaneous cerebrospinal fluid rhinorrhea (CSFR). METHODS: A retrospective study was conducted on 18 patients of CSFR. Nasal secretion was collected for biochemical analysis. Imaging examination was done for identification of the bony defect in skull base. RESULTS: In all cases, the glucose concentration of nasal secretion were more than 1.7 mmol/L, and the β-2 transferrin detected by immunoelectrophoresis technique were positive...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29735964/effect-of-thunder-fire-moxibustion-on-pain-quality-of-life-and-tension-of-multifidus-in-patients-with-primary-osteoporosis-a-randomized-controlled-trial
#10
Dao-Ming Xu, Huaning Xu, Jing Liu, Tong Wang, Wenzhong Wu, Lanying Liu, Qianmo Tian, Hanjun Li, Lili Zhang, Yana Cao
BACKGROUND Primary osteoporosis is a common disease among postmenopausal women and the elderly; low back pain is the most typical clinical manifestation an is the primary reason for a clinic visit, and directly affects patients' quality of life. Anti-osteoporosis medications have undesirable side effects, and many kinds of special traditional Chinese moxibustion methods have been widely used in the clinical treatment of osteoporosis low back pain. The purpose of this study was to observe whether thunder-fire moxibustion therapy, compared to calcium supplements alone, can ease osteoporosis low back pain, improve quality of life, and reduce tension of the multifidus...
May 8, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29732540/retraction-sunlight-exposure-is-important-for-preventing-hip-fractures-in-patients-with-alzheimer-s-disease-parkinson-s-disease-or-stroke-by-j-iwamoto-t-takeda-and-h-matsumoto
#11
(no author information available yet)
The above article from Acta Neurologica Scandinavica, published online on 18 June 2011 in Wiley Online Library (http://wileyonlinelibrary.com) and in Volume 125, pp. 279-284, has been retracted by agreement between the authors, the Journal Editor-in-Chief Elinor Ben-Menachem and John Wiley & Sons Ltd. The Retraction has been agreed due to extensive duplication of previously published material on the part of Dr Sato, who has acknowledged full responsibility. Dr. Iwamoto would like to note the following information related to this retraction: Dr...
June 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29727228/osteosarcopenia
#12
James Paintin, Cyrus Cooper, Elaine Dennison
Osteosarcopenia is a newly described syndrome that describes the co-existence of osteoporosis and sarcopenia, two chronic musculoskeletal conditions associated with ageing. Osteoporosis, a condition of low bone mass and micro-architectural deterioration of bone, and sarcopenia, the loss of muscle mass, strength and function, often co-exist in a frail subset of the elderly population, leading to significantly worsened outcomes than seen in either condition alone. These include a greater risk of falls, fractures and institutionalization, and significant socioeconomic costs...
May 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/29721240/mexican-patients-with-hiv-have-a-high-prevalence-of-vertebral-fractures
#13
José Antonio Mata-Marín, Carla I Arroyo-Anduiza, María de Los Ángeles Berrospe-Silva, Alberto Chaparro-Sánchez, Ana Gil-Avila, Jesús Gaytán-Martínez
Low bone mineral density (BMD) and fragility fractures are common in individuals infected with HIV, who are undergoing antiretroviral therapy (ART). In high-income countries, dual energy X-ray absorptiometrry is typically used to evaluate osteopenia or osteoporosis in HIV infected individuals. However, this technology is unavailable in low andmiddle income countries, so a different approach is needed. The aim of this study was to use X-ray scans of the spine to determine the prevalence of and associated risk factors for vertebral fractures in HIVinfected patients in a tertiary-care hospital in Mexico...
March 29, 2018: Infectious Disease Reports
https://www.readbyqxmd.com/read/29705875/association-between-metabolic-syndrome-and-osteoporosis-in-taiwanese-middle-aged-and-elderly-participants
#14
Hsin-Hui Lin, Chun-Yuan Huang, Lee-Ching Hwang
This study examined the association between metabolic syndrome and osteoporosis among middle-aged and elderly Taiwanese participants. After controlling for body mass index, age, liver and renal functions, and nutrition and exercise statuses, we found no significant association between MS and osteoporosis in either gender. PURPOSE: The term metabolic syndrome (MS) encompasses different abnormalities with independent effects on bone metabolism, which has led to inconsistencies in the association between MS and osteoporosis...
April 28, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29705535/associations-of-myeloid-hematological-diseases-of-the-elderly-with-osteoporosis-a-longitudinal-analysis-of-routine-health-care-data
#15
Thomas Datzmann, Freya Trautmann, Falko Tesch, Anna Mies, Lorenz C Hofbauer, Uwe Platzbecker, Jochen Schmitt
BACKGROUND: Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) are hematological stem cell diseases mainly of the elderly. Studies indicate a close relationship between bone metabolism and hematopoietic stem cells within the osteo-hematopoietic niche. However, it remains unclear how the disturbed interaction within the osteo-hematopoietic niche affects bone homeostasis in MDS and AML patients. METHODS: We utilized data of a large German statutory health insurance of approximately 2 million persons living in the German federal state of Saxony...
April 21, 2018: Leukemia Research
https://www.readbyqxmd.com/read/29705177/the-impact-of-exercise-and-vitamin-d-supplementation-on-physical-function-in-community-dwelling-elderly-individuals-a-randomized-trial
#16
Kana Aoki, Mayumi Sakuma, Naoto Endo
BACKGROUND: We investigated the impact of exercise and vitamin D supplementation on physical function and locomotor dysfunction in community-dwelling elderly individuals. METHODS: In total, 148 community-dwelling elderly individuals (aged ≥60 years) who were not taking osteoporosis medications participated in a 24-week intervention. The participants were randomly divided into an exercise group, vitamin D group, and exercise and vitamin D group. The participants and outcome-assessing staff were not blinded to group assignment...
April 25, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29704640/homocysteine-levels-are-associated-with-bone-resorption-in-pre-frail-and-frail-spanish-women-the-toledo-study-for-healthy-aging
#17
Nuria Álvarez-Sánchez, Ana Isabel Álvarez-Ríos, Juan Miguel Guerrero, Francisco José García-García, Leocadio Rodríguez-Mañas, Ivan Cruz-Chamorro, Patricia Judith Lardone, Antonio Carrillo-Vico
BACKGROUND: Homocysteine (Hcy) high levels are associated with fractures, bone resorption and an early onset of osteoporosis in elderly persons; a relationship between Hcy and bone formation has also been suggested but is still controversial. Frailty, an independent predictor of fractures and decreased bone mineral density is associated with altered bone metabolism in women. However, no previous works have studied the relationship among frailty, Hcy levels and bone turnover. METHODS: We studied the association among Hcy, osteoporosis and N-terminal propeptide of type I procollagen (PINP), C-terminal telopeptide of type I collagen (β-CTX), parathyroid hormone (PTH), calcium and 25-hydroxyvitamin D (25(OH)D) in 631 Spanish women between the ages of 65-78 from the Toledo Study for Healthy Aging (TSHA) cohort, who were classified as highly functional (robust subjects) or non-robust (pre-frail or frail subjects) according to Fried's criteria...
April 25, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29703028/osteoporosis-and-fracture-after-gastrectomy-for-stomach-cancer-a-nationwide-claims-study
#18
Gi Hyeon Seo, Hae Yeon Kang, Eun Kyung Choe
This study was planned to evaluate the incidence and risk factors of osteoporosis and fracture after gastrectomy for stomach cancer using a nationwide claims database in South Korea.Data from 41,512 patients (50-79 years) who underwent gastrectomy for stomach cancer from 2008 to 2010 with at least 5 years of follow-up were obtained from the Health Insurance Review and Assessment Service database. Patients diagnosed with osteoporosis and prescribed bisphosphonate or raloxifene or who experienced osteoporotic fractures after gastrectomy were operationally defined as osteoporosis...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29700604/fragility-fractures-of-the-sacrum-occur-in-elderly-patients-with-severe-loss-of-sacral-bone-mass
#19
Daniel Wagner, Alexander Hofmann, Lukas Kamer, Takeshi Sawaguchi, R Geoff Richards, Hansrudi Noser, Dominik Gruszka, Pol M Rommens
INTRODUCTION: Patients suffering from osteoporosis-associated fragility fractures of the sacrum (FFS; also termed sacral insufficiency fractures) are increasingly observed. They have typical fracture patterns with fracture lines located in the sacral ala. When treating these patients operatively, iliosacral screw loosening is not uncommon. We aimed to study the sacral bone mass in patients presenting with a FFS using 3D statistical models. MATERIALS AND METHODS: 3D models of averaged Hounsfield units (HU) were generated based on CT scans from 13 patients with a unilateral FFS (mean age 79...
April 26, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29696936/relationship-of-calcification-in-the-carotid-or-coronary-arteries-and-osteoporosis-in-the-elderly
#20
Jie Zhu, Feng Guo, Jie Zhang, Chunli Mu
BACKGROUND: To investigate the correlation between senile osteoporosis and calcified plaques in the arteries and to study the common potential risk factors for loss of bone mass and calcified plaques in the arteries. METHODS: Eligible patients (≥60 years old) who received treatment in our hospital from January 2016 to December2016 were included in this study. Bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry (DXA). Multivariate regression model was used to analyze the correlation of osteoporosis and loss of bone mass with the risk of calcified plaques in the carotid and coronary arteries...
April 24, 2018: Minerva Medica
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