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https://www.readbyqxmd.com/read/29218310/non-invasive-hemodynamic-monitoring-for-hemodynamic-management-in-perioperative-medicine
#1
Julia Y Nicklas, Bernd Saugel
No abstract text is available yet for this article.
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29218264/role-of-pet-ct-for-precision-medicine-in-lung-cancer-perspective-of-the-society-of-nuclear-medicine-and-molecular-imaging
#2
Bennett S Greenspan
This article discusses the role of PET/CT in contributing to precision medicine in lung cancer, and provides the perspective of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) on this process. The mission and vision of SNMMI are listed, along with the guidance provided by SNMMI to promote best practice in precision medicine. Basic principles of PET/CT are presented. An overview of the use of PET/CT imaging in lung cancer is discussed. In lung cancer patients, PET/CT is vitally important for optimal patient management...
December 2017: Translational Lung Cancer Research
https://www.readbyqxmd.com/read/29217935/bronchoscopy-in-nigerian-clinical-practice-a-survey-of-medical-doctors-perception-use-and-associated-challenges
#3
Adekunle Olatayo Adeoti, Olufemi Olumuyiwa Desalu, Joseph Olusesan Fadare, Wemimo Alaofin, Cajetan Chigozie Onyedum
Background: Bronchoscopy is a vital diagnostic and therapeutic procedure in pulmonological practice. The aim of this study was to determine the perception, use and challenges encountered by Nigerian medical doctors involved in this procedure. Materials and Methods: A cross-sectional study was conducted among 250 medical doctors recruited from three major tertiary institutions in Nigeria between September 2013 and June 2014. A semi-structured questionnaire was self-administered to adult physicians, paediatricians, and surgeons as well as their trainees to obtain their perception, use and associated challenges in the use of bronchoscopy in clinical practice...
July 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29217149/mucous-membrane-pemphigoid-with-ocular-involvement-the-clinical-phenotype-and-its-relationship-to-direct-immunofluorescence-findings
#4
Hon Shing Ong, Jane F Setterfield, Darwin C Minassian, John K Dart
PURPOSE: This study explored the validity of the First International Consensus on Mucous Membrane Pemphigoid (MMP) guidance, which recommends that clinically indistinguishable patients, who have direct immunofluorescence (DIF)-negative biopsies, be excluded from a diagnosis of MMP. Misdiagnosis, or delayed diagnosis, of MMP with ocular involvement leads to the inappropriate use of topical therapy, the standard of care for causes of cicatrising conjunctivitis other than MMP, rather than systemic immunomodulatory therapy, resulting in irreversible clinical deterioration in patients with MMP...
December 4, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29216852/access-to-affordable-medicines-and-diagnostic-tests-for-asthma-and-copd-in-sub-saharan-africa-the-ugandan-perspective
#5
Davis Kibirige, Leaticia Kampiire, David Atuhe, Raymond Mwebaze, Winceslaus Katagira, Winters Muttamba, Rebecca Nantanda, William Worodria, Bruce Kirenga
BACKGROUND: Equitable access to affordable medicines and diagnostic tests is an integral component of optimal clinical care of patients with asthma and chronic obstructive pulmonary disease (COPD). In Uganda, we lack contemporary data about the availability, cost and affordability of medicines and diagnostic tests essential in asthma and COPD management. METHODS: Data on the availability, cost and affordability of 17 medicines and 2 diagnostic tests essential in asthma and COPD management were collected from 22 public hospitals, 23 private and 85 private pharmacies...
December 8, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29215655/observed-frequency-and-challenges-of-variant-reclassification-in-a-hereditary-cancer-clinic
#6
Sarah Macklin, Nisha Durand, Paldeep Atwal, Stephanie Hines
PurposeEfforts have been made by the American College of Medical Genetics and Genomics and the Association for Molecular Pathology to make variant classification more uniform, but many limitations remain. Reclassification of a variant of uncertain significance (VUS) is expected, but other more certain calls, like pathogenic or benign, can also be reclassified once additional information is gathered. Variant reclassification can create difficult circumstances for both patients and clinicians.MethodsRetrospective review of all variant reclassifications in genes associated with hereditary cancer syndromes at one clinic between September 2013 and February 2017 was completed...
December 7, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29215204/titanium-fiber-plates-for-bone-tissue-repair
#7
Takashi Takizawa, Noboru Nakayama, Hisao Haniu, Kaoru Aoki, Masanori Okamoto, Hiroki Nomura, Manabu Tanaka, Atsushi Sobajima, Kazushige Yoshida, Takayuki Kamanaka, Kumiko Ajima, Ayumu Oishi, Chika Kuroda, Haruka Ishida, Satomi Okano, Shinsuke Kobayashi, Hiroyuki Kato, Naoto Saito
Titanium plates are widely used in clinical settings because of their high bone affinity. However, owing to their high elastic modulus, these plates are not suitable for bone repair since their proximity to the bone surface for prolonged periods can cause stress shielding, leading to bone embrittlement. In contrast, titanium fiber plates prepared by molding titanium fibers into plates by simultaneously applying compression and shear stress at normal room temperature can have an elastic modulus similar to that of bone cortex, and stress shielding will not occur even when the plate lies flush against the bone's surface...
December 7, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29214870/advances-in-cell-free-protein-array-methods
#8
Xiaobo Yu, Brianne Petritis, Hu Duan, Danke Xu, Joshua LaBaer
Cell-free protein microarrays represent a special form of protein microarray which display proteins made fresh at the time of the experiment, avoiding storage and denaturation. They have been used increasingly in basic and translational research over the past decade to study protein-protein interactions, the pathogen-host relationship, post-translational modifications, and antibody biomarkers of different human diseases. Their role in the first blood-based diagnostic test for early stage breast cancer highlights their value in managing human health...
December 7, 2017: Expert Review of Proteomics
https://www.readbyqxmd.com/read/29214627/a-12-month-descriptive-analysis-of-emergency-intubations-at-brooke-army-medical-center-a-national-emergency-airway-registry-study
#9
Michael D April, Steven G Schauer, Calvin A Brown Rd, Patrick C Ng, Jessie Fernandez, Andrea E Fantegrossi, Joseph K Maddry, Shane Summers, Daniel J Sessions, Robert M Barnwell, Mark Antonacci
Emergency airway management is a critical skill for military healthcare providers. Our goal was to describe the Emergency Department (ED) intubations at Brooke Army Medical Center (BAMC) over a 12-month period. MATERIAL AND METHODS: Physicians performing endotracheal intubations in the BAMC ED complete data collection forms for each intubation event as part of the National Emergency Airway Registry, including patient demographics, intubation techniques, success and failure rates, adverse events, and patient disposition...
October 2017: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/29214621/sandfly-fever-in-afghanistan-a-sometimes-overlooked-disease-of-military-importance-a-case-series-and-review-of-the-literature
#10
John W Downs, Daniel T Flood, Nicholas H Orr, Jason A Constantineau, James W Caviness
Sandfly fever, sometimes known as pappataci fever or Phlebotomus fever, is a vector transmitted viral illness with a history of affecting naïve military formations that travel through or fight in areas in which the infection is endemic. We present a series of 4 hospitalized cases of sandfly fever (2 presumptive, 2 laboratory confirmed) that were admitted to a Role 3 hospital in Afghanistan for evaluation and treatment following medical evacuation from a forward area for marked fevers and malaise. Laboratory evaluation of these cases was significant for leukopenia and thrombocytopenia, consistent with historical descriptions of sandfly fever...
October 2017: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/29214395/pharmacological-management-of-hereditary-angioedema-with-c1-inhibitor-deficiency-in-pediatric-patients
#11
REVIEW
Henriette Farkas
Hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) is a form of bradykinin-mediated angioedema. It is a rare disorder with an onset during childhood in most instances. Therefore, familiarity with the options for the management of pediatric cases is indispensable. The recurrent angioedematous episodes do not respond to conventional treatments and may evolve into a life-threatening condition. In view of the recommendations adopted by international consensus in 2016, patient management and follow-up should be guided by an individualized strategy...
December 7, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/29214243/intracellular-investigation-on-the-differential-effects-of-4-polyphenols-on-mcf-7-breast-cancer-cells-by-raman-imaging
#12
A Mignolet, B R Wood, E Goormaghtigh
The past decades have seen significant interest in the study of polyphenolic compounds as potential therapeutic agents in medicine because they display a vast array of cellular effects beneficial to treat or manage a plethora of chronic diseases including inflammatory diseases, cardiovascular abnormalities and several types of cancer. These compounds act at different stages of carcinogenesis but deciphering their mode of action is a complex task. Live MCF-7 breast cancer cells were investigated using Raman imaging to evaluate the perturbations induced after incubating cells with four different polyphenols: EGCG, gallic acid, resveratrol and tannic acid...
December 7, 2017: Analyst
https://www.readbyqxmd.com/read/29214048/good-vaccination-practice-it-all-starts-with-a-good-vaccine-storage-temperature
#13
Frédéric Vangroenweghe
Background: Recent introduction of strategies to reduce antibiotic use in food animal production implies an increased use of vaccines in order to prevent the economic impact of several important diseases in swine. Good Vaccination Practice (GVP) is an overall approach on the swine farm aiming to obtain maximal efficacy of vaccination through good storage, preparation and finally correct application to the target animals. In order to have a better insight into GVP on swine farms and the vaccine storage conditions, a survey on vaccination practices was performed on a farmers' fair and temperatures in the vaccine storage refrigerators were measured during farm visits over a period of 1 year...
2017: Porcine Health Management
https://www.readbyqxmd.com/read/29214027/to-what-extent-do-prescribing-practices-for-hypertension-in-the-private-sector-in-zimbabwe-follow-the-national-treatment-guidelines-an-analysis-of-insurance-medical-claims
#14
Victor Basopo, Paschal N Mujasi
Background: Hypertension is the most prevalent cardiovascular disease in Zimbabwe. The prevalence of Hypertension in the country is above 30% regardless of the cut off used. Currently, majority of patients in Zimbabwe seek health care from the private sector due to limited government funding for the public health sector. However, Standard treatment guidelines for hypertension are only available in the public sector and are optional in the private sector. This study assesses compliance of private sector prescribing to Standard Treatment guidelines for hypertension...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/29212546/electronic-laboratory-medicine-ordering-with-evidence-based-order-sets-in-primary-care-elmo-study-protocol-for-a-cluster-randomised-trial
#15
Nicolas Delvaux, An De Sutter, Stijn Van de Velde, Dirk Ramaekers, Steffen Fieuws, Bert Aertgeerts
BACKGROUND: Laboratory testing is an important clinical act with a valuable role in screening, diagnosis, management and monitoring of diseases or therapies. However, inappropriate laboratory test ordering is frequent, burdening health care spending and negatively influencing quality of care. Inappropriate tests may also result in false-positive results and potentially cause excessive downstream activities. Clinical decision support systems (CDSSs) have shown promising results to influence the test-ordering behaviour of physicians and to improve appropriateness...
December 6, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29212079/plasma-et-1-concentrations-are-elevated-in-pregnant-women-with-hypertension-meta-analysis-of-clinical-studies
#16
Yong-Ping Lu, Ahmed Abdallah Hasan, Shufei Zeng, Berthold Hocher
BACKGROUND/AIMS: The ET system might be involved in the pathogenesis of hypertensive disorders during pregnancy. The objective is to analyse the impact of ET-1 in hypertensive pregnant women by a strict meta-analysis of published human clinical studies. METHODS: Based on the principle of Cochrane systematic reviews, Cohort studies in PubMed (Medline), Google Scholar and China Biological Medicine Database (CBM-disc) designed to identify the role of endothelin-1 (ET-1) in the pathophysiology of gestational hypertension and preeclampsia were screened...
November 28, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29211054/barriers-and-facilitators-for-information-exchange-during-over-the-counter-consultations-in-community-pharmacy-a-focus-group-study
#17
Liza J Seubert, Kerry Whitelaw, Fabienne Boeni, Laetitia Hattingh, Margaret C Watson, Rhonda M Clifford
Consumers are confident managing minor ailments through self-care, often self-medicating from a range of over-the-counter (OTC) medicines available from community pharmacies. To minimise risks, pharmacy personnel endeavour to engage in a consultation when consumers present with OTC enquiries however they find consumers resistant. The aim was to determine stakeholder perspectives regarding barriers and facilitators for information exchange during OTC consultations in community pharmacies and to understand the elicited themes in behavioural terms...
December 6, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29210973/manuka-honey-a-case-study-of-severe-atopic-eczematous-dermatitis-reaction-to-henna-tattoo
#18
Jeanine Harrison
Many mainstream medications were derived from plants and originally utilized in patient management well prior to the extensive research and testing processes of current pharmaceutical standards. The evolution of therapeutic management within the pharmaceutical and skin care industry often uses synthetic processing of products with less of a focus on the natural ingredients from which they were originally derived. However, more recently there has been a shift in pharmacological management to include the therapeutic use of more holistic medicines and practices and thus a broadening of the uses of nontraditional medical treatment options...
October 2017: Plastic Surgical Nursing
https://www.readbyqxmd.com/read/29210936/optical-coherence-tomography-and-histology-of-age-related-macular-degeneration-support-mitochondria-as-reflectivity-sources
#19
Katie M Litts, Yuhua Zhang, K Bailey Freund, Christine A Curcio
PURPOSE: Widespread adoption of optical coherence tomography has revolutionized the diagnosis and management of retinal disease. If the cellular and subcellular sources of reflectivity in optical coherence tomography can be identified, the value of this technology will be advanced even further toward precision medicine, mechanistic thinking, and molecular discovery. Four hyperreflective outer retinal bands are created by the exquisite arrangement of photoreceptors, Müller cells, retinal pigment epithelium, and Bruch membrane...
November 23, 2017: Retina
https://www.readbyqxmd.com/read/29210755/recruitment-of-dual-career-academic-medicine-couples
#20
Charles W Putnam, Judy DiMarco, Charles B Cairns
Today it is not uncommon to discover that a candidate for a faculty position has a partner or spouse who is also an academician, adding complexity to the recruitment process. Here, the authors address two practical obstacles to the recruitment of faculty who have an academic partner: dual recruitment and conflict-of-interest. The authors have found that tandem recruitment works best when suitable positions for both spouses are first identified so that recruitment can proceed synchronously. This approach decreases misperceptions of favoritism toward either's candidacy...
November 28, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
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