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Calcification

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https://www.readbyqxmd.com/read/29792740/colloid-adenocarcinoma-of-the-lung-ct-and-pet-ct-findings-in-seven-patients
#1
Han Kyul Kim, Joungho Han, Teri J Franks, Kyung Soo Lee, Tae Jung Kim, Joon Young Choi, Jaeil Zo
OBJECTIVE: We aimed to assess CT and 18 F-FDG PET/CT findings of colloid adenocarcinoma of the lung in seven patients. MATERIALS AND METHODS: From 2010 to 2017, seven patients with surgically proven colloid adenocarcinoma of the lung were identified. CT (both enhanced and unenhanced) and PET/CT findings were analyzed, and the imaging features were compared with histopathologic reports. Clinical and demographic features were also analyzed. RESULTS: In all cases except one, tumors showed low attenuation on unenhanced CT scans, ranging in attenuation from -16...
May 24, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29792302/blood-pressure-patterns-and-subsequent-coronary-artery-calcification-in-women-who-delivered-preterm-births
#2
Janet M Catov, Gabrielle G Snyder, Abigail Fraser, Cora E Lewis, Kiang Liu, Andrew D Althouse, Marnie Bertolet, Erica P Gunderson
Women who delivered preterm infants have excess cardiovascular disease, but vascular pathways linking these conditions are not understood. We considered that higher blood pressure over 25 years among women with preterm delivery may be associated with coronary artery calcification (CAC). The CARDIA study (Coronary Artery Risk Development in Young Adults) enrolled 1049 black and white women with births between 1985 and 2010 (n=272 ever preterm [<37 weeks]; n=777 all term births [≥37 weeks]). Latent mixture modeling identified blood pressure trajectories across 20 years, and these were related to CAC at years 20 and 25...
May 23, 2018: Hypertension
https://www.readbyqxmd.com/read/29792135/modified-ldl-immune-complexes-and-cardiovascular-disease
#3
Maria F Lopes-Virella, Gabriel Virella
Modified forms of LDL, both spontaneously formed in the organism or prepared in the laboratory, are immunogenic. As a consequence, antigen-antibody complexes (immune complexes, IC) formed in vivo can be measured in the peripheral blood, and their levels are strong predictors of cardiovascular disease (CVD). It has been possible to generate antibodies that recognize different LDL modifications, allowing the analysis of circulating IC constitution. Clinical studies showed that the antigenic constitution of the IC has a modulating effect on the development of CVD...
May 23, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29791971/predictors-of-treatment-success-after-collagenase-clostridium-histolyticum-injection-for-peyronie-s-disease-development-of-a-nomogram-from-a-multicentre-single-arm-non-placebo-controlled-clinical-study
#4
Andrea Cocci, Giorgio Ivan Russo, Alberto Briganti, Andrea Salonia, Giovanni Cacciamani, Marco Capece, Marco Falcone, Massimiliano Timpano, Gianmartin Cito, Paolo Verze, Bruno Giammusso, Giuseppe Morgia, Vincenzo Mirone, Andrea Minervini, Mauro Gacci, Tommaso Cai, Sergio Serni, Marco Carini, Gianluca Giubilei, Nicola Mondaini
OBJECTIVE: To build-up a nomogram able to predict treatment success after Collagenase clostridium histolyticum (CCH) for Peyronie's disease (PD). MATERIAL AND METHODS: From November 2016 to November 2017, we enrolled 135 patients with PD in a multicentre single-arm prospective study. All patients enrolled had a treatment with CCH. Success of therapy was defined as a penile curvature decrease of at least 20 degrees from baseline curvature. Treatment satisfaction was assessed using a scale from 1 to 10 and high satisfaction was arbitral defined as a score ≥8...
May 23, 2018: BJU International
https://www.readbyqxmd.com/read/29791933/infantile-basal-ganglia-stroke-after-mild-head-trauma-associated-with-mineralizing-angiopathy-of-lenticulostriate-arteries-an-under-recognized-entity
#5
Sandra P Toelle, Tamara Avetisyan, Nune Kuyumjyan, Biayna Sukhudyan, Eugen Boltshauser, Annette Hackenberg
Basal ganglia infarction in young children, mostly after mild head trauma, has been repeatedly reported. The pathogenesis and the risk factors are not fully understood. Lenticulostriate vasculopathy, usually referred to as basal ganglia calcification, is discussed as one of them. We describe five young (7-13 months old on presentation) male children who suffered from hemiparesis due to ischemic stroke of the basal ganglia, four of them after minor head trauma. All of them had calcification in the basal ganglia visible on computed tomography or cranial ultrasound but not on magnetic resonance imaging...
May 23, 2018: Neuropediatrics
https://www.readbyqxmd.com/read/29791638/assessment-of-ulceration-risk-in-diabetic-individuals
#6
Luz Marina Alfonso Dutra, Maria Rita Carvalho Garbi Novaes, Manuela Costa Melo, Danyelle Lorrane Carneiro Veloso, Dayane Leticia Faustino, Leila Maria Sales Sousa
OBJECTIVE: To identify the risk factors for foot ulceration through the tracing of diabetic peripheral neuropathy and peripheral arterial disease in individuals with type I and II diabetes, who were assisted in reference centers of the Federal District, Brazil. METHOD: a cross-sectional and analytical study, with the assessment of 117 individuals in outpatient clinics of the Federal District. Continuous variables were compared through Mann-Whitney test, and categorized variables, through Chi-square test for univariate analysis and Logistics regression test for multivariate analysis...
2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29791561/lymph-node-calcifications
#7
Edson Marchiori, Bruno Hochhegger, Gláucia Zanetti
No abstract text is available yet for this article.
April 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/29791200/evaluation-of-mandibular-odontogenic-keratocyst-and-ameloblastoma-by-panoramic-radiograph-and-computed-tomography
#8
Daniel Berretta Moreira Alves, Fabrício Mesquita Tuji, Fábio Abreu Alves, André Caroli Rocha, Alan Roger Dos Santos-Silva, Pablo Agustin Vargas, Márcio Ajudarte Lopes
OBJECTIVE: The purpose of this study was to describe and compare the main imagenological features of mandibular ameloblastomas and odontogenic keratocyst (OKC) using panoramic radiograph (PR) and computed tomography (CT). METHODS: The sample consisted of 9 cases of ameloblastomas and 9 cases of OKC. PR and CT images were analyzed according to shape, internal structure, borders, associated unerupted tooth, root resorption, expansion and perforation of cortical bones...
May 23, 2018: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29790720/recanalization-of-ctos-with-soundbitetm-active-wire
#9
Marianne Brodmann, Eric Thérasse, Andrew Benko, Louis-Philippe Riel, Steven Dion, Philippe Généreux, Martin Brouillette
BACKGROUND: The aim of this study was to examine the safety and efficacy of the SoundBite™ Crossing System for the recanalization of infrainguinal chronic total occlusion (CTO) lesions. CTOs are frequent among patients with severe claudication or critical limb ischemia. Failure to recanalize CTOs remains common and is associated with poor prognosis. The SoundBite™ Crossing System (SoundBite Medical Solutions Inc., Montreal, Canada) is a newly developed device that uses a 0.018-inch wire (SoundBite™ Active Wire) to deliver acoustic shock waves to the distal tip of a steerable guidewire to facilitate directed penetration of the proximal cap and crossing of the occlusion...
May 23, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29790252/should-we-still-be-utilizing-warfarin-in-the-type-2-diabetic-patient
#10
REVIEW
David S H Bell, Edison Goncalves
The frequency of non-valvular atrial fibrillation is increased by 40% in type 2 diabetic subjects and the thromboembolic risk associated with atrial fibrillation is increased by 79% compared with the non-diabetic individual with atrial fibrillation. Warfarin, the traditional anticoagulant used to prevent thromboembolism, is non-specific and affects several proteins outside the coagulation system. By decreasing the levels of matrix Gla protein there is an increase in coronary and renal artery calcification which has the potential to increase cardiovascular events and accelerate decline in renal function...
May 22, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29788540/unusual-presentation-of-calcific-tendinitis-of-the-iliopsoas-tendon-in-a-28-year-old-female
#11
Sonia Henry, Timothy Small, David Cottle
No abstract text is available yet for this article.
May 22, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29788425/patients-with-advanced-chronic-kidney-disease-and-vascular-calcification-have-a-large-hydrodynamic-radius-of-secondary-calciprotein-particles
#12
Wei Chen, Viktoriya Anokhina, Gregory Dieudonne, Matthew K Abramowitz, Randeep Kashyap, Chen Yan, Tong Tong Wu, Karen L de Mesy Bentley, Benjamin L Miller, David A Bushinsky
Background: The size of secondary calciprotein particles (CPP2) and the speed of transformation (T50) from primary calciprotein particles (CPP1) to CPP2 in serum may be associated with vascular calcification (VC) in patients with chronic kidney disease (CKD). Methods: We developed a high throughput, microplate-based assay using dynamic light scattering (DLS) to measure the transformation of CPP1 to CPP2, hydrodynamic radius (Rh) of CPP1 and CPP2, T50 and aggregation of CPP2...
May 16, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29788226/circulating-dp-ucmgp-is-associated-with-kidney-dysfunction-and-arterial-stiffness
#13
Houry Puzantian, Scott R Akers, Garrett Oldland, Khuzaima Javaid, Rachana Miller, Yueya Ge, Bilal Ansari, Jonathan Lee, Arpita Suri, Zeba Hasmath, Raymond Townsend, Julio A Chirinos
Background: Large artery stiffening is increased in advanced CKD, but likely develops progressively in earlier stages of CKD. Active matrix Gla-Protein (MGP) is a potent vitamin-K dependent inhibitor of vascular calcification. A recent animal model demonstrated intrinsic abnormalities in vitamin K metabolism even in early CKD, but whether early human CKD is associated with vascular vitamin K deficiency is unknown. Methods: We enrolled 137 adults without HF with varying degrees of renal function: normal eGFR (>90 mL/min; n=59), mildly reduced eGFR (stage 2 CKD: eGFR = 60-89 mL/min; n=53) or at least moderately reduced eGFR (stage 3-5 CKD; eGFR<60 ml/min; n=25)...
May 17, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29788044/clinical-and-haemodynamic-outcomes-of-balloon-expandable-transcatheter-mitral-valve-implantation-a-7-year-experience
#14
Marina Urena, Eric Brochet, Milena Lecomte, Caroline Kerneis, Jose Luis Carrasco, Walid Ghodbane, Jérémie Abtan, Soleiman Alkhoder, Richard Raffoul, Bernard Iung, Patrick Nataf, Alec Vahanian, Dominique Himbert
Aims: We analysed the early and long-term clinical and haemodynamic outcomes of balloon-expandable transcatheter mitral valve implantation (TMVI) in an experienced centre. Methods and results: All patients undergoing TMVI from July 2010 to July 2017 in our centre were prospectively included. Indication for TMVI relied on the judgement of the local heart team. Patients were followed at 1 month, 1 year, and yearly thereafter. A total of 91 patients underwent TMVI...
May 19, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29787872/development-of-a-preoperative-simulation-technique-for-carotid-endarterectomy-in-patients-with-contrast-contraindications
#15
Shunsuke Nomura, Motohiro Hayashi, Tatsuya Ishikawa, Koji Yamaguchi, Takakazu Kawamata
OBJECTIVE: Vascular and osteological parameters, such as the heights of the carotid bifurcation and distal end of the plaque, are important preoperative considerations for patients undergoing carotid stenosis procedures such as carotid endarterectomy. However, for patients with contrast contraindications such as allergies or nephropathies, three-dimensional computed tomography angiography (3D-CTA) is unavailable, and preoperative evaluation remains challenging. In the present study, we aimed to develop a preoperative simulation for use in patients with contrast-contraindicated carotid stenosis...
May 19, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29787363/nonepithelial-neoplasms-of-the-pancreas-part-2-malignant-tumors-and-tumors-of-uncertain-malignant-potential
#16
Maria A Manning, Edina E Paal, Amogh Srivastava, Koenraad J Mortele
Almost all neoplasms of the pancreas are derived from pancreatic epithelial components, including the most common pancreatic mass, primary pancreatic ductal adenocarcinoma (PDAC). Nonepithelial neoplasms comprise only 1%-2% of all pancreatic neoplasms. Although some may arise directly from intrapancreatic elements, many originate from mesenchymal, hematopoietic, or neural elements in the retroperitoneal peripancreatic space and grow into the pancreas. Once these tumors reach a certain size, it can be challenging to identify their origin...
May 25, 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29786701/lutembacher-syndrome-with-mitral-valve-calcification-in-a-31-year-old-male
#17
Arsalan Majeed Adam, Ansab Godil, Muhammad Saad Ali Mallick, Fahad Khan, Ather Hasan Rizvi, Inam-Ul-Haq Muhammad Makhdoom
Lutembacher syndrome is characterized by a congenital ostium secundum atrial septal defect and an acquired mitral valve stenosis. We present a similar case in a 31-year old male who came in with orthopnoea, central cyanosis and pedal oedema. Examination revealed cardiac murmurs in tricuspid and apical regions. Chest x-ray showed signs of pulmonary congestion and ventricular enlargement. Electrocardiogaphy (ECG) revealed right axis deviation and right bundle branch block along with atrial fibrillation and Transthoracic Echocardiography (TTE) showed abnormal valves (mitral stenosis with calcification and tricuspid regurgitation) and dilated cardiac chambers...
February 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/29786640/vitamin-d-in-vascular-calcification-a-double-edged-sword
#18
REVIEW
Jeffrey Wang, Jimmy J Zhou, Graham R Robertson, Vincent W Lee
Vascular calcification (VC) as a manifestation of perturbed mineral balance, is associated with aging, diabetes and kidney dysfunction, as well as poorer patient outcomes. Due to the current limited understanding of the pathophysiology of vascular calcification, the development of effective preventative and therapeutic strategies remains a significant clinical challenge. Recent evidence suggests that traditional risk factors for cardiovascular disease, such as left ventricular hypertrophy and dyslipidaemia, fail to account for clinical observations of vascular calcification...
May 22, 2018: Nutrients
https://www.readbyqxmd.com/read/29786482/human-epidermal-growth-factor-2-positive-breast-cancer-with-mammographic-microcalcification-relationship-to-pathologic-complete-response-after-neoadjuvant-chemotherapy
#19
Fayyaz A K Mazari, Nisha Sharma, David Dodwell, Kieran Horgan
Purpose To determine the relationship between the presence or absence of mammographic calcifications in human epidermal growth factor receptor 2 (HER2)-positive breast cancers and pathologic complete response (pCR) to neoadjuvant chemotherapy and to determine other tumor and clinical characteristics that may be predictive of such a response. Materials and Methods A database of all patients with HER2-positive breast cancer who underwent neoadjuvant chemotherapy between 2007 and 2015 was retrospectively reviewed...
May 16, 2018: Radiology
https://www.readbyqxmd.com/read/29786466/mineralo-organic-nanoparticles-in-health-and-disease-an-overview-of-recent-findings
#20
Jan Martel, Cheng-Yeu Wu, Hsin-Hsin Peng, John D Young
We observed earlier that mineralo-organic nanoparticles form in human body fluids when the concentrations of calcium, carbonate and phosphate exceed saturation. The particles have been shown to represent mineral precursors in developing bones and teeth as well as in ectopic calcification and kidney stones. Recent studies suggest that the mineral particles may also be involved in other physiological processes, including immune tolerance against the gut microbiota and food antigens. We review here the involvement of mineralo-organic nanoparticles in physiological and pathological processes and discuss recent findings that reveal novel and unexpected roles for these particles in the human body...
May 22, 2018: Nanomedicine
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