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Food allergy in asia

Linglin Fu, Jinbao Wang, Saiqiao Ni, Chong Wang, Yanbo Wang
Chinese shrimp (Penaeus chinensis) is widely cultured and consumed in Asia, but is also a major food allergen locally. Though to be the foundation of preventing and treating allergy, the allergenic epitopes of major allergens tropomyosin (TM) and arginine kinase (AK) in Penaeus chinensis have not been identified. Here, we applied Immunoinfo-CB (immunoinformatics coupled with competitive-binding strategy) to address the point. Potential allergenic epitopes of TM and AK were predicted by multiple immunoinformatics tools, followed by validating with inhibitory dot-blot assay, indirect competition ELISA and mast cell degranulation assay...
February 26, 2018: Journal of Agricultural and Food Chemistry
Ying-Yang Xu, Jia Yin
Yam (Dioscorea opposita) is commonly consumed in East Asia, but allergic reaction to this plant food is rare. To date, there is no report of anaphylactic reaction after ingestion of cooked yam. We described 3 cases with anaphylaxis after eating boiled yam and 1 present with oral allergy syndrome as well. Basophil activation test in patients showed positive reactivity to boiled yam extract. In immunoblotting, a 30-kDa protein was recognized by all patients' sera and a 17-kDa band was detected by 1 patient. N-terminal amino acid revealed the 30-kDa IgE reacted band was DB3S, dioscorin in Dioscorea tuber...
January 2018: Asia Pacific Allergy
Mari Sasaki, Rachel L Peters, Jennifer J Koplin, Michael J Field, Vicki McWilliam, Susan M Sawyer, Peter J Vuillermin, Angela Pezic, Lyle C Gurrin, Jo A Douglass, Mimi L K Tang, Shyamali C Dharmage, Katrina J Allen
BACKGROUND: Despite the rising rates of anaphylaxis in older children and adolescents, risk factors for food allergy among this age group are understudied. OBJECTIVE: The objective of this study was to investigate the risk factors for current adolescent food allergy using a population-based sample. METHODS: The SchoolNuts study was a questionnaire survey among 10- to 14-year-old adolescents and their parents, followed by clinic evaluation including oral food challenge when food allergy was suspected from questionnaire response...
January 31, 2018: Journal of Allergy and Clinical Immunology in Practice
Chinreddy Subramanyam Reddy, Seong Cheol Kim, Mok Hur, Yeon Bok Kim, Chun Geon Park, Woo Moon Lee, Jae Ki Jang, Sung Cheol Koo
Angelica gigas Nakai (AGN) is a crucial oriental medicinal herb that grows especially in Korea and the Far-East countries. It contains chemically active compounds like pyranocoumarins, polyacetylenes and essential oils, which might be useful for treatment of several chronic diseases. It has been used for centuries as a traditional medicine in Southeast Asia, but in Western countries is used as a functional food and a major ingredient of several herbal products. The genus Angelica is also known as 'female ginseng' due to its critical therapeutic role in female afflictions, such as gynecological problems...
December 7, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
T Ruethers, M Raith, M F Sharp, M Koeberl, J N Stephen, R Nugraha, T T K Le, S Quirce, H X M Nguyen, S D Kamath, S S Mehr, D E Campbell, C R Bridges, A C Taki, I Swoboda, A L Lopata
BACKGROUND: Fish is a well-recognized cause of food allergy and anaphylaxis. The evolutionary and taxonomic diversity of the various consumed fish species pose a challenge in the identification and characterization of the major fish allergens critical for reliable diagnostics. Globally, fish is a rising cause of food allergy complicated by a large under-investigated variety of species as well as increasing global tourism and trade. This is the first comprehensive study on allergen profiles of heat-processed fish from Vietnam...
November 28, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
Joan H Dunlop, Corinne A Keet
Understanding the epidemiology of food allergy is complicated by the difficulty of identifying it on a large scale. The prevalence of food allergy is higher in younger age groups and decreases with age. Allergy to peanut and egg seems to be more common in Northern Europe, the United States, Canada and Australia compared with Southern Europe, Eastern Europe and Asia, whereas shellfish and fish allergies may be more common in Asia. The rate of transient unrecognized food allergy may be high and variable recognition of food allergy may explain some of the differences seen in food allergy prevalence...
February 2018: Immunology and Allergy Clinics of North America
J G Burkhardt, A Chapa-Rodriguez, S L Bahna
"Gluten sensitivity" has become commonplace among the public. Wheat allergy (WA) and celiac disease (CD) are well-defined entities, but are becoming a fraction of individuals following a gluten-free diet (GFD). Wheat allergy has a prevalence of <0.5%. Wheat, specifically its omega-5 gliadin fraction, is the most common allergen implicated in food-dependent, exercise-induced anaphylaxis. CD is a non-IgE hypersensitivity to certain cereal proteins: gluten in wheat, secalin in rye, hordein in barley, and to a lesser extent avenin in oat...
November 13, 2017: Allergy
Elizabeth Huiwen Tham, Lynette Pei-Chi Shek, Hugo Ps Van Bever, Pakit Vichyanond, Motohiro Ebisawa, Gary Wk Wong, Bee Wah Lee
Emerging evidence for the early introduction of allergenic foods for the prevention of food allergies, such as peanut allergy in Western populations, has led to the recent publication of guidelines in the USA and Europe recommending early peanut introduction for high-risk infants with severe eczema or egg allergy. Peanut allergy is, however, much less prevalent in Asia compared to the West. Varying patterns of food allergy are seen even within Asian countries-such as a predominance of wheat allergy in Japan and Thailand and shellfish allergy in Singapore and the Philippines...
February 2018: Pediatric Allergy and Immunology
Jordan Leroy, Marjorie Cornu, Anne Sophie Deleplancque, SĂ©verine Loridant, Emmanuel Dutoit, Boualem Sendid
We describe a case of imported cutaneous gnathostomiasis in a Thai patient living in France. Gnathostomiasis is a zoonosis of food origin. The disease is endemic in Southeast Asia and Latin America. However, over the past 30 years, an increasing number of imported cases has been described in Europe and America. The disease is rare in Western Europe and the majority of cases described had a cutaneous clinical presentation. The disease may sometimes be confused with allergy, leading to a delay in diagnosis. Visceral symptoms are rare but may follow severe attacks...
October 16, 2017: Travel Medicine and Infectious Disease
Noriyuki Yanagida, Sakura Sato, Kyohei Takahashi, Ken-Ichi Nagakura, Kiyotake Ogura, Tomoyuki Asaumi, Motohiro Ebisawa
BACKGROUND: Buckwheat (BW) is a common cause of life-threatening allergy in Asia. Few have examined oral food challenges (OFCs) using BW. We here describe the OFC outcomes for the diagnosis or confirmation of tolerance acquisition and clarify risk factors for positive OFCs. METHODS: Between July 2005 and March 2014, we retrospectively reviewed data from children who underwent OFCs using 3,072 mg of BW protein at Sagamihara National Hospital. Children were suspected of having BW allergy because of positive results for BW-specific IgE or because they had been previously diagnosed with BW allergy owing to immediate reactions to BW...
2017: International Archives of Allergy and Immunology
Sinjira Somanunt, Sasawan Chinratanapisit, Punchama Pacharn, Nualanong Visitsunthorn, Orathai Jirapongsananuruk
BACKGROUND: Atopic dermatitis (AD) is the first manifestation of Atopic March. The natural history of AD and predictive factors for Atopic March have not been widely studied in Asia. OBJECTIVE: To study the natural history and associated factors of disease remission and risk of respiratory allergy in Thai children with AD. METHOD: Medical records of AD patients attending Allergy clinic at Siriraj hospital from 2004-2014 were reviewed. Patients were further followed-up to obtain current symptoms and treatment...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
Schweta R Arakali, Todd D Green, Chitra Dinakar
OBJECTIVE: To evaluate the published medical literature on the prevalence and types of food allergies in South Asia. DATA SOURCES: A PubMed search was performed using the keywords India and food allergy, Asia and food allergy, and South Asia and food allergy for any period. Articles cited in selected studies were reviewed for their appropriateness of inclusion into this review. STUDY SELECTIONS: Publications were included that were original research and fit the topic of food allergy and South Asia...
January 2017: Annals of Allergy, Asthma & Immunology
Harriet Moonesinghe, Heather Mackenzie, Carina Venter, Sally Kilburn, Paul Turner, Kellyn Weir, Taraneh Dean
BACKGROUND: Accurate information on the prevalence of food allergy facilitates a more evidence-based approach to planning of allergy services and can identify important geographic variations. OBJECTIVE: To conduct a systematic review to assess the age-specific prevalence of fish and shellfish allergy worldwide. METHODS: Searches were conducted using Web of Science and PubMed. Population-based cross-sectional studies and cohort studies that examined the prevalence of fish and shellfish allergy (IgE mediated and non-IgE mediated) at an identifiable point in time were eligible for inclusion in the study...
September 2016: Annals of Allergy, Asthma & Immunology
Scott P Commins
The syndrome of delayed allergic reactions to the carbohydrate galactose-alpha-1,3-galactose ("alpha-gal") has become increasingly recognized in allergy and immunology clinics regionally throughout the southeastern USA. Due to the increasing awareness of this unique food allergy, cases have been identified in the northeastern and central USA as well as in Central and South America, Europe, Asia, Scandinavia, and Australia. Clinically, alpha-gal allergy is characterized by reactions to non-primate mammalian meat (e...
September 2016: Current Allergy and Asthma Reports
Kyoung Yong Jeong, Mina Son, June Yong Lee, Kyung Hee Park, Jae-Hyun Lee, Jung-Won Park
Boiled silkworm pupa is a traditional food in Asia, and patients with silkworm pupa food allergy are common in these regions. Still now only one allergen from silkworm, arginine kinase, has been identified. The purpose of this study was to identify novel food allergens in silkworm pupa by analyzing a protein extract after heat treatment. Heat treated extracts were examined by proteomic analysis. A 27-kDa glycoprotein was identified, expressed in Escherichia coli, and purified. IgE reactivity of the recombinant protein was investigated by ELISA...
January 2016: Journal of Korean Medical Science
Lydia Wong, Chiung Hui Huang, Bee Wah Lee
Crustacean shellfish allergy is an important cause of food allergy and anaphylaxis in Asia. The major allergen in shellfish allergy is tropomyosin, a pan-allergen that is also found in house dust mites and cockroaches. Tropomyosins from house dust mites (HDMs) have a high sequence homology to shellfish tropomyosins, and cross-reactivity between HDM and shrimp tropomyosins has been demonstrated. Exposure to inhaled tropomyosins from house dust mites has been postulated to be the primary sensitizer for shellfish allergy, in a reaction analogous to the oral allergy (inhalant-food) syndrome...
March 2016: Allergy, Asthma & Immunology Research
Xiangjie Zhao, Lin Li, Zheshi Kuang, Guoqing Luo, Bing Li
This study explored food allergy caused by eating silkworm (Bombyx mori L.) pupae, a traditionally accepted food and animal feed in East and Southeast Asia, and identified two new allergens by proteomic and immunological methods. Proteins isolated from silkworm pupae were separated by two-dimensional gel electrophoresis (2-DE); pooled sera from patients allergic to silkworm pupa proteins were used to detect immunoglobulin E (IgE)-binding proteins by western blotting, and allergens specific for silkworm pupa consumption-caused allergy were visualised with the ECL reagents...
2015: Central-European Journal of Immunology
Theresa N H Leung, K L Hon
Eczema or atopic dermatitis is a common childhood atopic disease associated with chronicity and impaired quality of life. As there is no cure for the disease, treatment relies on topical and systemic anti-allergic or immunomodulating therapies. Topical corticosteroid, macrolide immunosuppressants, and oral immunomodulating drugs for recalcitrant disease have been the mainstay of therapy. Management of atopic dermatitis must consider the individual symptomatic variability of the disease. Basic therapy is focused on patient/family education, hydrating topical treatment, and avoidance of specific and non-specific provocative factors...
June 2015: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
Jong Hyun Choi, Jae Kyoem Sim, Jee Youn Oh, Gyu-Young Hur, Kyung Hoon Min, Sung Yong Lee, Jae Jeong Shim, Kyung Ho Kang
Mulberry (Morus spp.) is a widespread deciduous tree and its fruit is commonly eaten in Korea and eastern Asia. Some reports demonstrate that mulberry fruit is a food allergen in the Mediterranean area. However, there has been no report of systemic allergic reactions after ingesting mulberry fruit in Korea. An 18-year-old boy with a mulberry fruit allergy visited our allergy clinic. He had experienced generalized urticaria, chest tightness, breathing difficulty, and abdominal cramping after ingesting mulberry fruit...
March 2015: Allergy, Asthma & Immunology Research
Vera Stejskal
BACKGROUND: The multiple symptoms of chronic fatigue syndrome (CFS) and fibromyalgia resemble those described in patients suffering from autoimmune/inflammatory syndrome induced by adjuvants (ASIA). It has been suggested that chronic metal-induced inflammation might play a role both in CFS and fibromyalgia as well as in ASIA. Humans are exposed to metals mainly through the release of metal ions from corroding dental restorations and orthopedic implants, food, vaccines and jewelry. Metals readily bind to sulphur and other groups in the mitochondria, enzymes and cell proteins...
December 2014: Israel Medical Association Journal: IMAJ
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