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https://www.readbyqxmd.com/read/29344985/probing-the-microscopic-environment-of-23-na-ions-in-brain-tissue-by-mri-on-the-accuracy-of-different-sampling-schemes-for-the-determination-of-rapid-biexponential-t2-decay-at-low-signal-to-noise-ratio
#1
Jonathan M Lommen, Sebastian Flassbeck, Nicolas G R Behl, Sebastian Niesporek, Peter Bachert, Mark E Ladd, Armin M Nagel
PURPOSE: To investigate and to reduce influences on the determination of the short and long apparent transverse relaxation times ( T2,s*, T2,l*) of 23 Na in vivo with respect to signal sampling. METHODS: The accuracy of T2* determination was analyzed in simulations for five different sampling schemes. The influence of noise in the parameter fit was investigated for three different models. A dedicated sampling scheme was developed for brain parenchyma by numerically optimizing the parameter estimation...
January 17, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29344847/the-effect-of-surgical-management-of-endometrioma-on-the-ivf-icsi-outcomes-when-compared-with-no-treatment-a-systematic-review-and-meta-analysis
#2
M Nickkho-Amiry, R Savant, K Majumder, E Edi-O'sagie, M Akhtar
OBJECTIVE: To assess the impact of surgical management of endometrioma on the outcome of assisted reproduction treatment (ART). DESIGN: A systematic review and meta-analysis. SETTING: Department of reproductive medicine at teaching university hospital, UK. PATIENTS: Subfertile women with endometrioma undergoing ART. INTERVENTIONS: Surgical removal of endometrioma or expectant management. MAIN OUTCOME MEASURES: Clinical pregnancy rate, pregnancy rate, live birth rate, number of oocytes retrieved and number of embryos available and ovarian response to gonadotrophins...
January 17, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29342070/an-evaluation-of-industry-relationships-among-contributors-to-aaos-clinical-practice-guidelines-and-appropriate-use-criteria
#3
Jake X Checketts, Courtney Cook, Matt Vassar
BACKGROUND: A long-standing relationship between orthopaedic surgeons and industry has made financial conflicts of interest a concerning issue. Research supports that financial conflicts of interest can influence both medical research and clinical practice. Financial conflicts of interest may also influence clinical practice guideline recommendations and their corresponding appropriate use criteria. Because of the influential nature of these guidelines, it is imperative that care be taken to minimize bias during guideline development...
January 17, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29338857/obstetric-complications-after-frozen-versus-fresh-embryo-transfer-in-women-with-polycystic-ovary-syndrome-results-from-a-randomized-trial
#4
Bo Zhang, Daimin Wei, Richard S Legro, Yuhua Shi, Jing Li, Lin Zhang, Yan Hong, Gang Sun, Ting Zhang, Weiping Li, Zi-Jiang Chen
OBJECTIVE: To evaluate the effect of frozen embryo transfer on maternal and neonatal complications of singleton and twin pregnancies compared with fresh embryo transfer in women with polycystic ovary syndrome (PCOS). DESIGN: A secondary analysis of a multicenter, randomized, controlled trial comparing live birth after frozen vs. fresh embryo transfer (FreFro-PCOS). SETTING: Reproductive medicine centers. PATIENT(S): A total of 1,508 patients with a diagnosis of PCOS who were undergoing IVF were enrolled...
January 12, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29327382/retrospective-analysis-of-forward-and-reverse-abo-typing-discrepancies-among-patients-and-blood-donors-in-a-tertiary-care-hospital
#5
R N Makroo, B Kakkar, S Agrawal, M Chowdhry, B Prakash, P Karna
OBJECTIVE: The aim of our study was to determine the incidence and causes of ABO typing discrepancies among patients and blood donors at our centre. BACKGROUND: An accurate interpretation of the ABO blood group of an individual is of utmost importance to ensure patient safety and good transfusion practices. METHODS: A retrospective observational study was carried out in the Department of Transfusion Medicine in our hospital from March 2013 to December 2015...
January 12, 2018: Transfusion Medicine
https://www.readbyqxmd.com/read/29325555/the-readiness-of-hospital-pharmacists-in-kuwait-to-practise-evidence-based-medicine-a-cross-sectional-study
#6
Ali Jasem Buabbas, Fatemah Mohammad Alsaleh, Hamza Mohamad Al-Shawaf, Ali Abdullah, Abdullah Almajran
BACKGROUND: The evolving role of pharmacists in providing pharmaceutical care, as part of the healthcare team, challenges them to acquire up-to-date knowledge of medicines to make the best clinical decisions. The volume of medical literature is on the increase, and it is important to utilise these resources to optimise patients' therapeutic outcomes. This study aimed at assessing the readiness of government hospital pharmacists in practising evidence-based medicine (EBM) in Kuwait in regards to their attitude, knowledge and skills, as well as the perceived barriers and facilitators...
January 11, 2018: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/29323538/clinical-characteristics-and-outcomes-of-traditional-chinese-medicine-induced-liver-injury-a-systematic-review
#7
Ran Wang, Xingshun Qi, Eric Yoshida, Nahum Mendez-Sanchez, Rolf Teschke, Mingyu Sun, Xu Liu, Chunping Su, Jiao Deng, Han Deng, Feifei Hou, Xiaozhong Guo
BACKGROUNDS: Traditional Chinese medicine (TCM) is becoming increasingly popular and related adverse events are often ignored or underestimated. AIMS: This systematic review aimed to evaluate the clinical characteristics and outcomes of TCM-induced liver injury (TCM-ILI) and to estimate the proportion of TCM-ILI in all drug-induced liver injuries (DILI). METHODS: China National Knowledge Infrastructure, Wanfang, VIP, PubMed, and Embase databases were searched...
January 11, 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29322473/pharmaceutical-care-and-health-related-quality-of-life-outcomes-over-the-past-25%C3%A2-years-have-we-measured-dimensions-that-really-matter
#8
REVIEW
Mohammed A Mohammed, Rebekah J Moles, Timothy F Chen
Background Several measures of Health-Related Quality of Life (HRQoL) have been used to evaluate Pharmaceutical Care (PC) interventions in the past decades. However, their suitability for evaluation of PC services has not been comprehensively evaluated. Aim of the review The aim of this review was to perform content analysis of HRQoL measures used in PC studies to gain an insight into their suitability for evaluation of PC services. Method PC studies evaluating HRQoL as a primary or secondary outcomes were retrieved based on a literature search of articles published from 1990 to 2015, on Medline, Embase, International Pharmaceutical Abstracts, Global Health, PsycInfo, Web of Science, Cinahl, HealthStar, Cochrane Library, AUSThealth, Australian Medical Index, and Current content...
January 10, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29321555/fourier-transform-infrared-microscopy-enables-guidance-of-automated-mass-spectrometry-imaging-to-predefined-tissue-morphologies
#9
Jan-Hinrich Rabe, Denis A Sammour, Sandra Schulz, Bogdan Munteanu, Martina Ott, Katharina Ochs, Peter Hohenberger, Alexander Marx, Michael Platten, Christiane A Opitz, Daniel S Ory, Carsten Hopf
Multimodal imaging combines complementary platforms for spatially resolved tissue analysis that are poised for application in life science and personalized medicine. Unlike established clinical in vivo multimodality imaging, automated workflows for in-depth multimodal molecular ex vivo tissue analysis that combine the speed and ease of spectroscopic imaging with molecular details provided by mass spectrometry imaging (MSI) are lagging behind. Here, we present an integrated approach that utilizes non-destructive Fourier transform infrared (FTIR) microscopy and matrix assisted laser desorption/ionization (MALDI) MSI for analysing single-slide tissue specimen...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29321113/top-cited-publications-on-point-of-care-ultrasound-the-evolution-of-research-trends
#10
Shao-Feng Liao, Pai-Jung Chen, Chung-Hsien Chaou, Ching-Hsing Lee
STUDY OBJECTIVES: Point-of-care ultrasound (POCUS) has been a rapidly growing and broadly used modality in recent decades. The purpose of this study was to determine how POCUS is incorporated into clinical medicine by analyzing trends of use in the published literature. METHODS: POCUS-related publications were retrieved from the Web of Science (WoS) database. The search results were ranked according to the number of times an article was cited during three time frames and average annual number of citations...
January 6, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29318825/-design-and-implementation-of-chinese-materia-medica-resources-survey-results-display-system
#11
Hui Wang, Xiao-Bo Zhang, Xiao-Guang Ge, Yan Jin, Ling Wang, Yan-Ping Zhao, Zhi-Xian Jing, Lan-Ping Guo, Lu-Qi Huang
From the beginning of the fourth national census of traditional Chinese medicine resources in 2011, a large amount of data have been collected and compiled, including wild medicinal plant resource data, cultivation of medicinal plant information, traditional knowledge, and specimen information. The traditional paper-based recording method is inconvenient for query and application. The B/S architecture, JavaWeb framework and SOA are used to design and develop the fourth national census results display platform...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29317005/a-quantitative-systematic-review-and-meta-analysis-of-the-effectiveness-of-oral-cholera-vaccine-as-a-reactive-measure-in-cholera-outbreaks
#12
Patricia Schwerdtle, Coretta-Kings Onekon, Katrina Recoche
Introduction The efficacy of oral cholera vaccines (OCVs) in laboratory conditions has been established, and the World Health Organization (WHO; Geneva, Switzerland) has recommended their preventative use in high-risk settings. The WHO recommendation has not been fully operationalized, nor has it been extended to apply to the reactive use of OCVs in real field epidemic conditions due to concerns about potential resource diversion, feasibility, cost, and acceptability. The purpose of this study is to assess and synthesize existing evidence of OCV effectiveness when used reactively in real field conditions...
January 10, 2018: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29316880/structure-formats-of-randomised-controlled-trial-abstracts-a-cross-sectional-analysis-of-their-current-usage-and-association-with-methodology-reporting
#13
Fang Hua, Tanya Walsh, Anne-Marie Glenny, Helen Worthington
BACKGROUND: The reporting of randomised controlled trial (RCT) abstracts is of vital importance. The primary objective of this study was to investigate the association between structure format and RCT abstracts' quality of methodology reporting, informed by the current requirement and usage of structure formats by leading general medical/internal medicine journals (secondary objective). METHODS: A two-part cross-sectional study. First, through hand searches, we identified all RCTs published in the top-50 high-impact general medical/internal medicine journals during July-December 2015 (n = 370), and retrieved the 'instructions to authors' of these journals...
January 10, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29301223/thinking-in-pharmacy-practice-a-study-of-community-pharmacists-clinical-reasoning-in-medication-supply-using-the-think-aloud-method
#14
Hayley Croft, Conor Gilligan, Rohan Rasiah, Tracy Levett-Jones, Jennifer Schneider
Medication review and supply by pharmacists involves both cognitive and technical skills related to the safety and appropriateness of prescribed medicines. The cognitive ability of pharmacists to recall, synthesise and memorise information is a critical aspect of safe and optimal medicines use, yet few studies have investigated the clinical reasoning and decision-making processes pharmacists use when supplying prescribed medicines. The objective of this study was to examine the patterns and processes of pharmacists' clinical reasoning and to identify the information sources used, when making decisions about the safety and appropriateness of prescribed medicines...
December 31, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29299903/delayed-ejaculation-pathophysiology-diagnosis-and-treatment
#15
REVIEW
Ibrahim A Abdel-Hamid, Omar I Ali
Delayed ejaculation (DE) is a poorly defined and uncommon form of male sexual dysfunction, characterized by a marked delay in ejaculation or an inability to achieve ejaculation. It is often quite concerning to patients and their partners, and sometimes frustrates couples' attempts to conceive. This article aims to review the pathophysiology of DE and anejaculation (AE), to explore our current understanding of the diagnosis, and to present the treatment options for this condition. Electronic databases were searched from 1966 to October 2017, including PubMed (MEDLINE) and Embase...
January 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29291006/the-application-of-precis-2-ratings-in-randomized-controlled-trials-of-chinese-herbal-medicine
#16
Liming Lu, Li Zhou, Jing Dong, Yu Xiang, Zehuai Wen
This study tests the feasibility of applying the pragmatic-explanatory continuum indicator summary (version "PRECIS-2") tool to randomized controlled trials of Chinese herbal medicine. A search was conducted to identify potentially eligible randomized controlled trials. Using the PRECIS-2 tool, assessment of trials was performed independently by 2 evaluators using a scale of 1-5 for each criterion (1 = maximal efficacy, 5 = maximal effectiveness). A total of 7,166 reports were retrieved from databases and 159 were included in the full text...
December 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/29286412/basic-research-in-plasma-medicine-a-throughput-approach-from-liquids-to-cells
#17
Sander Bekeschus, Anke Schmidt, Felix Niessner, Torsten Gerling, Klaus-Dieter Weltmann, Kristian Wende
In plasma medicine, ionized gases with temperatures close to that of vertebrate systems are applied to cells and tissues. Cold plasmas generate reactive species known to redox regulate biological processes in health and disease. Pre-clinical and clinical evidence points to beneficial effects of plasma treatment in the healing of chronic ulcer of the skin. Other emerging topics, such as plasma cancer treatment, are receiving increasing attention. Plasma medical research requires interdisciplinary expertise in physics, chemistry, and biomedicine...
November 17, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29275156/aripiprazole-use-during-pregnancy-peripartum-and-lactation-a-systematic-literature-search-and-review-to-inform-clinical-practice
#18
REVIEW
A Cuomo, A Goracci, A Fagiolini
BACKGROUND: Aripiprazole is used relatively frequently in women with bipolar disorder or schizophrenia in childbearing years, owing to its efficacy and relatively favorable side effect profile. As is the case for other psychotropic medications, for ethical reasons, no prospective randomized placebo controlled trial to assess aripiprazole safety during pregnancy has ever been conducted. However, animal data are available and the amount of exposure and outcome data for human fetuses and infants has recently increased, providing published prospective safety data in relatively large numbers of pregnant women treated with aripiprazole...
December 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29259640/effectiveness-and-safety-of-the-combination-of-the-traditional-chinese-medicine-prescription-jade-screen-and-desloratadine-in-the-treatment-of-chronic-urticaria-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#19
REVIEW
Shao-Fei Yuan, Jing-Zhi Guan, Yong Hao, Jian-Yuan Chai, Feng-Li Gao, Su-Qin Shi, Jian-Xin Wang, Jin He, Ji-Hai Shi
Objective: The aim of this study is to systematically evaluate the clinical efficacy and safety of the traditional Chinese medicine prescription Jade Screen combined with desloratadine in the treatment of chronic urticaria. Methods: Two researchers independently conducted literature searches. The extracted data were analyzed using Rev Man 5.2.3 software. The established retrieval time range of the various databases was up to 15 March, 2017. Results: Sixteen randomized controlled trials were included in this study...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29258915/cinnamon-a-promising-prospect-towards-alzheimer-s-disease
#20
REVIEW
Saeideh Momtaz, Shokoufeh Hassani, Fazlullah Khan, Mojtaba Ziaee, Mohammad Abdollahi
Over the last decades, an exponential increase of efforts concerning the treatment of Alzheimer's disease (AD) has been practiced. Phytochemicals preparations have a millenary background to combat various pathological conditions. Various cinnamon species and their biologically active ingredients have renewed the interest towards the treatment of patients with mild-to-moderate AD through the inhibition of tau protein aggregation and prevention of the formation and accumulation of amyloid-β peptides into the neurotoxic oligomeric inclusions, both of which are considered to be the AD trademarks...
December 16, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
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