keyword
https://read.qxmd.com/read/38648027/follicular-infundibular-tricholemmal-squamous-cell-carcinoma-a-new-who-entity-clinicopathological-features-in-103-cases-including-follow-up-and-implications-for-patient-management
#21
JOURNAL ARTICLE
Richard A Carr, James Wiggins, David N Slater
AIMS: Cutaneous follicular (infundibular-tricholemmal) squamous cell carcinoma (FSCC) is a new World Health Organization entity. We present the largest series of published cases, summarizing clinical data, diagnostic criteria, differential diagnosis, and implications for patient management. METHODS: Cases were identified from 2004 to 2011. Inclusion criteria included discrete attachment(s) of the tumor to the overlying epidermis via follicular infundibula, tricholemmal keratinization, and cellular pleomorphism...
April 23, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38647421/identifying-potential-cases-of-eating-disorders-in-an-acute-medical-hospital
#22
JOURNAL ARTICLE
Vivien Hui In Cheung, Lauren J Christie, Terri Maister, Devlin Higgins, David Williams, Nikki Woods, Melissa Armstrong, Susan Hart
OBJECTIVE: To identify patients presenting to an acute medical hospital with common signs and symptoms that occur in people with eating disorders (EDs), and determine by retrospective file audit if these are diagnosed cases of an ED. METHOD: The investigators screened electronic medical records of people 16 years and older for common signs and symptoms of an ED such as hypokalemia, in patients presenting to an acute hospital in Sydney, Australia from 2018 to 2020...
April 22, 2024: International Journal of Eating Disorders
https://read.qxmd.com/read/38646856/correcting-mucogingival-deformities-for-pescatarian-patients-a-clinical-case-study
#23
Hyung Jae Jung, Nadeem Karimbux, Irina F Dragan
AIM: This clinical case study is to highlight the improvement of periodontal health of mandibular canines using a soft tissue alternative of fish origin, a piscine graft. METHODS: A 37-year-old female patient was referred to a periodontal practice for evaluation of mucogingival deformities around teeth #22 and #27 that were also diagnosed with recession, lack of keratinized tissue (KT), and bilateral high frenum attachment. Multiple soft tissue treatment options were presented to the patient, including autogenous, allograft, or xenograftporcine or piscine...
April 22, 2024: Clinical Advances in Periodontics
https://read.qxmd.com/read/38646852/the-impact-of-three-learning-methods-on-dental-students-satisfaction-and-knowledge-acquisition
#24
JOURNAL ARTICLE
Sara M Toema, Nihal S Amer, Paul C Jones
OBJECTIVES: Health professionals' education presents unique challenges including clinical application of knowledge and interprofessional collaboration. Additionally, institutions suffer from faculty shortages while class sizes increase. Therefore, educators seek innovative andragogical techniques utilizing minimal resources. Several active learning methods have been introduced as a solution. The aim of this study is to assess the impact of lecture (LBL), case (CBL), and team (TBL) based learning on the students' satisfaction and knowledge attainment...
April 22, 2024: Journal of Dental Education
https://read.qxmd.com/read/38646821/evaluation-of-implicit-bias-training-in-continuing-medical-and-nursing-education-to-address-racial-bias-in-maternity-health-care-settings
#25
JOURNAL ARTICLE
Kathryn Mishkin, Chasmine Flax
OBJECTIVES: Implicit bias can affect clinical decisions that influence the care received by patients whose ancestors had been subjected to unfair medical and social practices. However, literature describing the effects of implicit bias training as part of continuing medical and nursing education is scarce. We conducted a longitudinal evaluation of a training for maternal health care clinical and nonclinical staff. METHODS: A total of 80 staff members at 2 clinical sites in Cleveland, Ohio, participated in the training and evaluation in 2020 and 2021...
April 22, 2024: Public Health Reports
https://read.qxmd.com/read/38646744/applicability-of-the-generalized-wind-profile-model-over-mountainous-forests
#26
JOURNAL ARTICLE
Yun-Chao Pang, Tian Gao, Xiu-Fen Li, Tong-Bin Zhao, Xing-Chang Wang, Rong-Ping Li, Feng-Yuan Yu, Sheng-Lin Qu, De-Xiong Teng, Jiao-Jun Zhu
The analytical equation based on Monin-Obukhov (M-O) similarity theory ( i.e. , wind profile equation) has been adopted since 1970s for using in the prediction of wind vertical profile over flat terrains, which is mature and accurate. However, its applicability over complex terrains remains unknown. This applicability signifies the accuracy of the estimations of aerodynamic parameters for the boundary layer of non-flat terrain, such as zero-displacement height ( d ) and aerodynamic roughness length ( z0 ), which will determine the accuracy of frequency correction and source area analysis in calculating carbon, water, and trace gas fluxes based on vorticity covariance method...
March 2024: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://read.qxmd.com/read/38646610/bioelectronic-modulation-of-carotid-sinus-nerve-to-treat-type-2-diabetes-current-knowledge-and-future-perspectives
#27
REVIEW
Silvia V Conde, Joana F Sacramento, Ciro Zinno, Alberto Mazzoni, Silvestro Micera, Maria P Guarino
Bioelectronic medicine are an emerging class of treatments aiming to modulate body nervous activity to correct pathological conditions and restore health. Recently, it was shown that the high frequency electrical neuromodulation of the carotid sinus nerve (CSN), a small branch of the glossopharyngeal nerve that connects the carotid body (CB) to the brain, restores metabolic function in type 2 diabetes (T2D) animal models highlighting its potential as a new therapeutic modality to treat metabolic diseases in humans...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38646270/robotic-archwire-bending-in-orthodontics-a-review-of-the-literature
#28
REVIEW
Babitha Merin George, Siddarth Arya, Shwetha G S, Keerthana Bharadwaj, Vaishnavi N S
Malocclusion is a widespread oral health issue that adversely affects individuals' health and well-being. Currently, fixed orthodontics is considered the most efficient treatment for correcting malocclusion, with archwire bending playing a key role in orthodontic treatment. Traditionally, orthodontists manually performed archwire bending using various handheld pliers and other mechanical tools, requiring a significant amount of time, precision, and specialized training yet being unable to guarantee appliance accuracy...
March 2024: Curēus
https://read.qxmd.com/read/38646236/information-sharing-in-neurosurgery-topics-among-pediatric-patients-and-loved-ones-within-the-reddit-community
#29
JOURNAL ARTICLE
Jocelyn To, Victoria J Horak, Donia Momen, Lekha Chirala, John Paul G Kolcun, Sandi Lam, Jeffrey Raskin
Introduction With crowd-sourced knowledge, patients arrive at their healthcare visits ready to play an active role. This exploratory study seeks to understand common concerns among patients and loved ones on Reddit, an anonymous internet forum. Ultimately, recognizing common concerns can aid providers in directing their conversations with patients. Methods Reddit posts in the "hot" tab of each subreddit were retroactively screened from September 1, 2022. Posts written within a five-year period were included...
March 2024: Curēus
https://read.qxmd.com/read/38646100/morphogenetic-theory-of-mental-and-cognitive-disorders-the-role-of-neurotrophic-and-guidance-molecules
#30
REVIEW
Alexandra Primak, Kirill Bozov, Kseniya Rubina, Stalik Dzhauari, Elena Neyfeld, Maria Illarionova, Ekaterina Semina, Dmitriy Sheleg, Vsevolod Tkachuk, Maxim Karagyaur
Mental illness and cognitive disorders represent a serious problem for the modern society. Many studies indicate that mental disorders are polygenic and that impaired brain development may lay the ground for their manifestation. Neural tissue development is a complex and multistage process that involves a large number of distant and contact molecules. In this review, we have considered the key steps of brain morphogenesis, and the major molecule families involved in these process. The review provides many indications of the important contribution of the brain development process and correct functioning of certain genes to human mental health...
2024: Frontiers in Molecular Neuroscience
https://read.qxmd.com/read/38646045/design-as-a-quality-improvement-strategy-the-case-for-design-expertise
#31
JOURNAL ARTICLE
Guillaume Lamé, Alexander Komashie, Carol Sinnott, Tom Bashford
Bad design in safety-critical environments like healthcare can lead to users being frustrated, excluded or injured. In contrast, good design can make it easier to use a service correctly, with impacts on both the safety and efficiency of healthcare delivery, as well as the experience of patients and staff. The participative dimension of design as an improvement strategy has recently gained traction in the healthcare quality improvement literature. However, the role of design expertise and professional design has been much less explored...
March 2024: Future Healthcare Journal
https://read.qxmd.com/read/38645441/erratum-addendum-validation-of-the-digital-health-literacy-assessment-among-the-university-students-in-china
#32
Limei Nie, Jiajia Zhao, Lutong Pan, Mingli Pang, Jieru Wang, Yue Zhou, Rui Chen, Hui Liu, Xixing Xu, Baochen Su, Fanlei Kong
[This corrects the article DOI: 10.3389/fpubh.2023.1294183.].
2024: Frontiers in Public Health
https://read.qxmd.com/read/38645174/placental-nanoparticle-mediated-igf1-gene-therapy-corrects-fetal-growth-restriction-in-a-guinea-pig-model
#33
Baylea N Davenport, Rebecca L Wilson, Alyssa A Williams, Helen N Jones
Fetal growth restriction (FGR) caused by placental insufficiency is a major contributor to neonatal morbidity and mortality. There is currently no in utero treatment for placental insufficiency or FGR. The placenta serves as the vital communication, supply, exchange, and defense organ for the developing fetus and offers an excellent opportunity for therapeutic interventions. Here we show efficacy of repeated treatments of trophoblast-specific human insulin-like 1 growth factor ( IGF1 ) gene therapy delivered in a non-viral, polymer nanoparticle to the placenta for the treatment of FGR...
April 10, 2024: bioRxiv
https://read.qxmd.com/read/38644958/value-and-limitations-of-urethrotech-catheterisation-device-to-manage-difficult-urethral-catheterisation-in-male-spinal-cord-injury-patients
#34
JOURNAL ARTICLE
Vaidyanathan Subramanian, Bakulesh Madhusudan Soni
METHODS: We used a Urethrotech catheterisation device in 57 male patients with spinal cord injury, in whom urethral catheterisation was unsuccessful or previous catheterisation was difficult. RESULTS: Urethrotech catheter could be inserted in 51 patients. No patient developed urinary tract infection. In one patient, the guidewire could not be introduced into the bladder, and a coude Foley catheter was inserted. In two patients, the guidewire was inserted into the bladder, but a 16 CH catheter could not be advanced over the guidewire...
2024: Medical Devices: Evidence and Research
https://read.qxmd.com/read/38644667/classification-and-stratification-in-pilonidal-sinus-disease-findings-from-the-pitstop-cohort
#35
JOURNAL ARTICLE
Matthew J Lee, Ellen Lee, Mike Bradburn, Daniel Hind, Emily B Strong, Farhat Din, Arkadiusz P Wysocki, Jon Lund, Christine Moffatt, Jonathan Morton, Asha Senapati, Helen Jones, Steven R Brown
AIM: Research in pilonidal disease faces several challenges, one of which is consistent and useful disease classification. The International Pilonidal Society (IPS) proposed a four-part classification in 2017. The aim of this work was to assess the validity and reliability of this tool using data from the PITSTOP cohort study. METHOD: Face validity was assessed by mapping the items/domains in the IPS tool against tools identified through a systematic review. Key concepts were defined as those appearing in more than two-thirds of published tools...
April 21, 2024: Colorectal Disease
https://read.qxmd.com/read/38644518/real-world-use-of-long-acting-cabotegravir-and-rilpivirine-12-month-results-of-the-injectable-antiretroviral-therapy-feasibility-study-jabs
#36
JOURNAL ARTICLE
M John, L Williams, G Nolan, M Bonnett, A Castley, D Nolan
OBJECTIVES: The inJectable Antiretroviral feasiBility Study (JABS) aimed to evaluate the implementation of long-acting regimens in a 'real world' Australian setting, with inclusion of participants with complex medical needs, social vulnerability and/or historical non-adherence. METHODS: JABS was a 12-month, single-centre, single-arm, open-label phase IV study of long-acting cabotegravir 600 mg plus rilpivirine 900 mg administered intramuscularly every 2 months to adults with treated HIV-1 infection...
April 21, 2024: HIV Medicine
https://read.qxmd.com/read/38644408/statistical-data-pre-processing-and-time-series-incorporation-for-high-efficacy-calibration-of-low-cost-no-2-sensor-using-machine-learning
#37
JOURNAL ARTICLE
Slawomir Koziel, Anna Pietrenko-Dabrowska, Marek Wojcikowski, Bogdan Pankiewicz
Air pollution stands as a significant modern-day challenge impacting life quality, the environment, and the economy. It comprises various pollutants like gases, particulate matter, biological molecules, and more, stemming from sources such as vehicle emissions, industrial operations, agriculture, and natural events. Nitrogen dioxide (NO2 ), among these harmful gases, is notably prevalent in densely populated urban regions. Given its adverse effects on health and the environment, accurate monitoring of NO2 levels becomes imperative for devising effective risk mitigation strategies...
April 21, 2024: Scientific Reports
https://read.qxmd.com/read/38644402/investigation-of-the-effectiveness-of-a-classification-method-based-on-improved-dae-feature-extraction-for-hepatitis-c-prediction
#38
JOURNAL ARTICLE
Lin Zhang, Jixin Wang, Rui Chang, Weigang Wang
Hepatitis C, a particularly dangerous form of viral hepatitis caused by hepatitis C virus (HCV) infection, is a major socio-economic and public health problem. Due to the rapid development of deep learning, it has become a common practice to apply deep learning to the healthcare industry to improve the effectiveness and accuracy of disease identification. In order to improve the effectiveness and accuracy of hepatitis C detection, this study proposes an improved denoising autoencoder (IDAE) and applies it to hepatitis C disease detection...
April 21, 2024: Scientific Reports
https://read.qxmd.com/read/38643704/milligram-scale-enantioresolution-of-promethazine-and-its-main-metabolites-determination-of-their-absolute-configuration-and-assessment-of-enantioselective-effects-on-human-sy-sy5y-cells
#39
JOURNAL ARTICLE
Maria Miguel Coelho, Inês Costa, Ana Carolina Ferreira de Albuquerque, Fernando Martins Dos Santos Junior, Bárbara Silva, Renata Silva, Carla Fernandes, Fernando Remião, Maria Elizabeth Tiritan
The misuse of pharmaceuticals has significantly increased in recent decades, becoming a major public health concern. The risks associated with medication misuse are particularly high in cases of overdose, especially when the active substances are chiral, as enantioselectivity plays an important role in toxicity. Promethazine (PMZ) is a chiral antihistamine marketed as a racemate and it is misused in "Purple Drank", a recreational drug beverage, that combines codeine and/or PMZ, with soda or alcohol leading to serious health consequences and fatalities in consumers around the world, particularly among teenagers...
April 15, 2024: Journal of Pharmaceutical and Biomedical Analysis
https://read.qxmd.com/read/38643662/assessment-of-knowledge-towards-first-aid-skills-of-epilepsy-among-undergraduate-health-students-in-riyadh-province-of-saudi-arabia-a-cross-sectional-study
#40
JOURNAL ARTICLE
Abdulrahman M Alshahrani, Naif Khalid Alsayed, Nemer Alotaibi, Mohammad Azhar Rashikh, Abdulrahman Talal Alghebaiwi, Faisal Faihan Alotaibi, Abdulaziz Faisal Alotaibi, Abdullah Mohammed Bin Hussain, Nawaf Mansour N Alotaibi, Mazen Saud Alotaibi
BACKGROUND: Applying proper first-aid measures to patients with seizure episodes plays a vital role in preventing the adverse consequences of seizures. Most previous data focused on teachers, healthcare providers and the general public. This study aimed to assess the knowledge of seizure first-aid measures among undergraduate health students. METHODS: This descriptive, cross-sectional study was conducted between May 16 and 31, 2023, with 493 undergraduate health students of Riyadh Province who answered online surveys...
April 20, 2024: Epilepsy & Behavior: E&B
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