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https://www.readbyqxmd.com/read/28428763/adhd-lifestyles-and-comorbidities-a-call-for-an-holistic-perspective-from-medical-to-societal-intervening-factors
#1
REVIEW
Simon Weissenberger, Radek Ptacek, Martina Klicperova-Baker, Andreja Erman, Katerina Schonova, Jiri Raboch, Michal Goetz
The review examines Attention Deficit Hyperactivity Disorder (ADHD in its Child and Adult form) and its various presentations (Hyperactive Impulsive, Inattentive, and Combined) with a particular focus on environmental (incl. social factors), lifestyles and comorbidities. It is argued that ADHD is best understood in a holistic and interactive context and a vast empirical literature is presented to illustrate the point: Environmental factors include stress in general as well as exposure to toxins (phthalates, bisphenol A)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28425778/meditation-awareness-training-for-the-treatment-of-workaholism-a-controlled-trial
#2
William Van Gordon, Edo Shonin, Thomas J Dunn, Javier Garcia-Campayo, Marcelo M P Demarzo, Mark D Griffiths
Background and aims Workaholism is a form of behavioral addiction that can lead to reduced life and job satisfaction, anxiety, depression, burnout, work-family conflict, and impaired productivity. Given the number of people affected, there is a need for more targeted workaholism treatments. Findings from previous case studies successfully utilizing second-generation mindfulness-based interventions (SG-MBIs) for treating behavioral addiction suggest that SG-MBIs may be suitable for treating workaholism. This study conducted a controlled trial to investigate the effects of an SG-MBI known as meditation awareness training (MAT) on workaholism...
April 20, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/28417948/erbb-family-signalling-a-paradigm-for-oncogene-addiction-and-personalized-oncology
#3
REVIEW
Nico Jacobi, Rita Seeboeck, Elisabeth Hofmann, Andreas Eger
ErbB family members represent important biomarkers and drug targets for modern precision therapy. They have gained considerable importance as paradigms for oncoprotein addiction and personalized medicine. This review summarizes the current understanding of ErbB proteins in cell signalling and cancer and describes the molecular rationale of prominent cases of ErbB oncoprotein addiction in different cancer types. In addition, we have highlighted experimental technologies for the development of innovative cancer cell models that accurately predicted clinical ErbB drug efficacies...
April 12, 2017: Cancers
https://www.readbyqxmd.com/read/28406661/lifetime-history-of-suicidal-ideation-and-attempts-among-incarcerated-women-in-israel
#4
Gila Chen, Keren Gueta
BACKGROUND: Evidence indicates that rates of death by suicide are higher among female inmates compared with male inmates and the general population. Despite the high rate of lifetime suicidality, little is known about the predictors of suicidality for these women. OBJECTIVE: The purpose was to examine sociodemographic, criminological, and psychological variables associated with a history of suicidal ideation and suicide attempts among incarcerated women. METHOD: This cross-sectional study investigated a history of suicidal ideation and suicide attempts in a sample of 46 Israeli incarcerated women...
April 13, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28402682/ibogaine-treatment-outcomes-for-opioid-dependence-from-a-twelve-month-follow-up-observational-study
#5
Geoffrey E Noller, Chris M Frampton, Berra Yazar-Klosinski
BACKGROUND: The psychoactive indole alkaloid ibogaine has been associated with encouraging treatment outcomes for opioid dependence. The legal status of ibogaine in New Zealand provides a unique opportunity to evaluate durability of treatment outcomes. OBJECTIVE: To examine longitudinal treatment effects over a 12-month period among individuals receiving legal ibogaine treatment for opioid dependence. METHOD: This observational study measured addiction severity as the primary outcome in 14 participants (50% female) over 12 months post-treatment using the Addiction Severity Index-Lite (ASI-Lite) following a single ibogaine treatment by either of two treatment providers...
April 12, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28399988/youth-social-behaviour-and-network-therapy-y-sbnt-adaptation-of-a-family-and-social-network-intervention-for-young-people-who-misuse-alcohol-and-drugs-a-randomised-controlled-feasibility-trial
#6
Judith Watson, Paul Toner, Ed Day, Donna Back, Louca-Mai Brady, Caroline Fairhurst, Charlotte Renwick, Lorna Templeton, Shabana Akhtar, Charlie Lloyd, Jinshuo Li, Kim Cocks, Sangeeta Ambegaokar, Steve Parrott, Paul McArdle, Eilish Gilvarry, Alex Copello
BACKGROUND: Family interventions appear to be effective at treating young people's substance misuse. However, implementation of family approaches in UK services is low. This study aimed to demonstrate the feasibility of recruiting young people to an intervention based on an adaptation of adult social behaviour and network therapy. It also sought to involve young people with experience of using substance misuse services in the research process. OBJECTIVES: To demonstrate the feasibility of recruiting young people to family and social network therapy and to explore ways in which young people with experience of using substance misuse services could be involved in a study of this nature...
March 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28379504/low-risk-of-producing-an-opioid-use-disorder-in-primary-care-by-prescribing-opioids-to-prescreened-patients-with-chronic-noncancer-pain
#7
Martin D Cheatle, Rollin M Gallagher, Charles P O'Brien
Objective. : To examine the risk of developing aberrant behaviors that might lead to a substance use disorder (addiction) when prescribing opioids for the relief of chronic noncancer pain in primary care settings. Design. : Longitudinal, prospective, descriptive design with repeated measures. Setting. : Private community-based internal medicine and family medicine clinics. Subjects. : Patients with chronic musculoskeletal pain...
March 31, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28378037/medical-disease-or-moral-defect-stigma-attribution-and-cultural-models-of-addiction-causality-in-a-university-population
#8
Nicole L Henderson, William W Dressler
This study examines the knowledge individuals use to make judgments about persons with substance use disorder. First, we show that there is a cultural model of addiction causality that is both shared and contested. Second, we examine how individuals' understanding of that model is associated with stigma attribution. Research was conducted among undergraduate students at the University of Alabama. College students in the 18-25 age range are especially at risk for developing substance use disorder, and they are, perhaps more than any other population group, intensely targeted by drug education...
April 4, 2017: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/28367351/predicting-inpatient-detoxification-outcome-of-alcohol-and-drug-dependent-patients-the-influence-of-sociodemographic-environment-motivation-impulsivity-and-medical-comorbidities
#9
Yvonne Sofin, Heidi Danker-Hopfe, Tina Gooren, Peter Neu
Aims. This prospective study aims to identify patient characteristics as predictors for treatment outcome during inpatient detoxification treatment for drug and alcohol dependent patients. Methods. A mixed gender sample of 832 consecutively admitted drug and alcohol dependent patients were interviewed by an experienced physician. The impact of a variety of factors concerning social environment, therapy motivation, impulsivity related variables, medical history, and addiction severity on treatment outcome was examined...
2017: Journal of Addiction
https://www.readbyqxmd.com/read/28364687/comorbidity-family-history-and-personality-traits-in-pathological-gamblers-compared-with-healthy-controls
#10
K Mann, T Lemenager, E Zois, S Hoffmann, H Nakovics, M Beutel, M Vogelgesang, K Wölfling, F Kiefer, M Fauth-Bühler
BACKGROUND: While DSM-5 classified pathological gambling as an addictive disorder, there is debate as to whether ICD-11 should follow suit. The debate hinges on scientific evidence such as neurobiological findings, family history of psychiatric disorders, psychiatric comorbidity, and personality variables. METHODS: In the "Baden-Württemberg Study of Pathological Gambling", we compared a group of 515 male pathological gamblers receiving treatment with 269 matched healthy controls...
December 23, 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28360785/determination-of-clinical-and-socio-demographical-differences-of-adolescents-applying-to-a-treatment-center-with-family-encouragement-or-the-decision-of-the-probation-office-and-determination-of-predictive-factors-in-maintaining-soberness-among-probation-cases
#11
Zeki Yüncü, Rezzan Aydin, Cahide Aydin, Burcu Özbaran, Sezen Köse
INTRODUCTION: This study has two objectives. The first objective of this study was the determination of some basic clinical and socio-demographical differences among the adolescents with substance abuse who apply to a treatment center with support from their family or by order of the probation office. The other objective of this study was the determination of the predictive factors in maintaining soberness among adolescents who successfully complete the probation treatment process. METHODS: The target population of this study is young adults under 19 years of age who apply to a substance addiction center for adolescents as a result of encouragement from their family or ordered by the Probation Office between 2005 and 2013...
June 2016: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28357191/psychiatric-co-morbidities-in-pregnant-women-with-opioid-use-disorders-prevalence-impact-and-implications-for-treatment
#12
REVIEW
Camila L Arnaudo, Barbara Andraka-Christou, Kacy Allgood
PURPOSE OF REVIEW: This review seeks to investigate three questions: What is the prevalence of comorbid psychiatric diagnoses among pregnant women with opioid use disorder (OUD)? How do comorbid psychiatric illnesses impact pregnant women with OUD? And how do comorbid psychiatric illnesses affect the ability of pregnant women with OUD to adhere to and complete OUD treatment? RECENT FINDINGS: Based on this literature review, 25-33% of pregnant women with OUD have a psychiatric comorbidity, with depression and anxiety being especially common...
2017: Current Addiction Reports
https://www.readbyqxmd.com/read/28340905/searching-objective-criteria-for-patient-assignment-in-addiction-treatment
#13
José J López-Goñi, Javier Fernández-Montalvo, Alfonso Arteaga, Sonia Esarte
The main aim of this study was to objectify the treatment assignment criteria used in a clinical centre for addiction treatment in Spain. A sample of 162 patients (87 inpatients and 75 outpatients) who sought treatment between 2010 and 2012 was assessed. Clinical characteristics (addiction severity, psychopathological symptoms, impulsiveness and maladjustment) of the two treatment groups (inpatient and outpatient) into which patients were assigned according to the clinical criteria of therapists were analysed to identify which variables were more relevant for patient placement...
May 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28339662/hiv-1-proteins-influence-novelty-seeking-behavior-and-alter-region-specific-transcriptional-responses-to-chronic-nicotine-treatment-in-hiv-1tg-rats
#14
Zhongli Yang, Tanseli Nesil, Taylor Wingo, Sulie L Chang, Ming D Li
Introduction: Clinical studies suggest that HIV-1-infected patients are more likely to use or abuse addictive drugs than is the general population. We hypothesized that HIV-1 proteins impact novelty-seeking behavior and enhance the transcriptional response to nicotine in genes implicated in both novelty-seeking behavior and drug addiction. Methods: We assessed the effects of HIV-1 proteins on novelty-seeking behavior by comparing baseline activity differences of HIV-1Tg and F344 control rats in the open-field test...
February 17, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28324807/parenting-self-efficacy-and-empowerment-among-expectant-mothers-with-substance-use-disorders
#15
Debra H Zand, Jessica L Chou, Kathy J Pierce, Lara B Pennington, Rosalie R Dickens, Jerri Michael, Donna McNamara, Taryn White
OBJECTIVE: to describe parenting self-efficacy and family empowerment among expectant mothers with substance use disorders. DESIGN: the study employed a quantitative cross-sectional design. PARTICIPANTS: participants were 71 pregnant women with substance use disorders entering a gender-specific, substance use disorder, residential treatment facility. MEASUREMENTS: measurement tools included: the demographic data form, the Parenting Sense of Competence Scale, the Addiction Severity Index, and the Family Empowerment Scale...
March 7, 2017: Midwifery
https://www.readbyqxmd.com/read/28296627/predictors-of-early-relapse-among-adolescent-crack-users
#16
Ronaldo Lopes-Rosa, Félix P Kessler, Thiago G Pianca, Luciano Guimarães, Pedro Ferronato, Esequiel Pagnussat, Helena Moura, Flavio Pechansky, Lisia von Diemen
Relapse is associated with a poor prognosis among drug users. Crack cocaine users are more prone to severe dependence because of the intensity of use. Additionally, initiating drug use during adolescence worsens users' prognosis due to the increased rates of impulsivity and other risk behaviors. This study aimed to identify the predictors of early relapse among adolescent crack users discharged from inpatient treatment. A cohort study was conducted with 89 psychiatric inpatients aged 12-17 years from two different hospitals in southern Brazil who met the criteria for crack abuse or dependence...
February 15, 2017: Journal of Addictive Diseases
https://www.readbyqxmd.com/read/28265714/a-short-history-of-the-5-ht2c-receptor-from-the-choroid-plexus-to-depression-obesity-and-addiction-treatment
#17
REVIEW
Jose M Palacios, Angel Pazos, Daniel Hoyer
This paper is a personal account on the discovery and characterization of the 5-HT2C receptor (first known as the 5-HT1C receptor) over 30 years ago and how it translated into a number of unsuspected features for a G protein-coupled receptor (GPCR) and a diversity of clinical applications. The 5-HT2C receptor is one of the most intriguing members of the GPCR superfamily. Initially referred to as 5-HT1CR, the 5-HT2CR was discovered while studying the pharmacological features and the distribution of [(3)H]mesulergine-labelled sites, primarily in the brain using radioligand binding and slice autoradiography...
March 7, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28236511/do-patient-characteristics-moderate-the-effect-of-extended-release-naltrexone-xr-ntx-for-opioid-use-disorder
#18
Peter D Friedmann, Donna Wilson, Edward V Nunes, Randall Hoskinson, Joshua D Lee, Michael Gordon, Sean M Murphy, Richard J Bonnie, Donna T Chen, Tamara Y Boney, Charles P O'Brien
BACKGROUND: Extended release naltrexone (XR-NTX) injected intramuscularly monthly has been shown to reduce relapse in persons with opioid use disorder. Baseline factors, including patients' demographics, comorbidities and lifestyle, may help identify patients who will benefit most or least from XR-NTX treatment. METHODS: Potential moderators of XR-NTX's effect were examined in the largest North American randomized open-label effectiveness trial of XR-NTX. Relapse status (Yes/No) at 6-month follow-up was regressed on treatment group (XR-NTX, N=153; or Treatment-as-Usual [TAU], N=155), baseline covariates, and their two-way interaction to identify moderator effects...
February 21, 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28224962/-gambling-in-elderly-patients
#19
Morgane Guillou Landreat, Jean-Yves Le Reste, Catherine Théréné-Mouden, Julie Caillon, Jennyfer Cholet, Marie Grall Bronnec
Behavioural addictions concern behaviour which generate pleasure (shopping, gambling, sex, etc.). Pathological gambling is the most common behavioural addiction in elderly people. It can be severely harmful causing psychological, financial and family problems and increasing the risk of suicide. Gambling addiction is underestimated in the elderly. Psychological, social and family support is important whatever the age, with treatment aiming to improve the person's quality of life, help them regain control of their gambling or stop altogether...
January 2017: Soins. Gérontologie
https://www.readbyqxmd.com/read/28178739/methamphetamine-consumption-during-pregnancy-effects-on-child-health
#20
Jürgen Dinger, Patricia Hinner, Jörg Reichert, Mario Rüdiger
Methamphetamine abuse during pregnancy represents an emerging health care problem. The consequences are not only of relevance to the pregnant women, but also their unborn child. It is associated with an increased risk of preeclampsia and hypertension, fetal demise, preterm delivery, and intrauterine growth restriction. The deleterious effects of prenatal methamphetamine exposure on the developing fetal brain may lead to long-term neuro-developmental and behavioral problems.Given the current evidence, abuse of methamphetamine during pregnancy must be of utmost concern to health care professionals and to policy-makers...
February 8, 2017: Pharmacopsychiatry
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