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https://www.readbyqxmd.com/read/27899120/violence-narratives-of-mexican-women-treated-in-mutual-aid-residential-centers-for-addiction-treatment
#1
Ignacio Lozano-Verduzco, Martha Romero-Mendoza, Rodrigo Marín-Navarrete
BACKGROUND: Violence against women is a social and public health issue in Mexico. The aim of this article is to explore violence among an understudied group of women, who attended Mutual-Aid Residential Centers for Addiction Treatment and experienced stigma both as women and addicts. These centers are particular kind of addiction treatment services that stem from 12-step philosophy, but that have been found to manipulate said philosophy and exercise extreme forms of psychological and physical violence...
November 30, 2016: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/27897471/use-of-risk-mitigation-practices-by-family-nurse-practitioners-prescribing-opioids-for-the-management-of-chronic-non-malignant-pain
#2
Sahil Chaudhary, Peggy Compton
BACKGROUND: Ongoing opioid analgesic use in patients suffering from chronic non-malignant pain (CNMP) has been associated with the development of opioid misuse, abuse, addiction, and overdose. To prevent these adverse outcomes, it is important that family nurse practitioners (FNPs) implement recommended risk mitigation practices (RMPs) when treating CNMP patients with opioids. METHODS: A national sample of 856 FNPs was invited to answer an online survey about their utilization of opioids and RMPs in treating CNMP...
November 29, 2016: Substance Abuse
https://www.readbyqxmd.com/read/27875549/the-synthetic-%C3%AE-nitrostyrene-derivative-cyt-rx20-inhibits-esophageal-tumor-growth-and-metastasis-via-pi3k-akt-and-stat3-pathways
#3
Wen-Chin Chiu, Yi-Chen Lee, Yu-Han Su, Yen-Yun Wang, Chun-Hao Tsai, Yi-An Hou, Chie-Hong Wang, Ying-Fong Huang, Chih-Jen Huang, Shah-Hwa Chou, Pei-Wen Hsieh, Shyng-Shiou F Yuan
The β-nitrostyrene family have been implicated for anti-cancer property. However, the pharmacological role of β-nitrostyrene in esophageal cancer remain unclear. Here, a β-nitrostyrene derivative, CYT-Rx20, was synthesized and assessed for its anti-cancer activities and underlying mechanism in esophageal cancer. CYT-Rx20 induced cytotoxicity in esophageal cancer cells by promoting apoptosis through activation of caspase cascade and poly(ADP-ribose) polymerase (PARP) cleavage. Besides, CYT-Rx20 inhibited esophageal cancer cell migration and invasion by regulating the expression of epithelial to mesenchymal transition (EMT) markers...
2016: PloS One
https://www.readbyqxmd.com/read/27855325/-not-human-dead-already-perceptions-and-experiences-of-drug-related-stigma-among-opioid-using-young-adults-from-the-former-soviet-union-living-in-the-u-s
#4
Alana Gunn, Honoria Guarino
BACKGROUND: Young people from the former Soviet Union (FSU) in the U.S. are engaging in opioid and injection drug use (IDU) in substantial numbers, paralleling nationwide trends. Yet opioid-using FSU immigrants face distinctive acculturation challenges, including perceived stigmatisation as drug users within their immigrant communities, which may exacerbate the negative health and psychosocial consequences of such use. METHODS: This qualitative study draws on semi-structured interviews with 26 FSU immigrant young adults (ages 18-29) living in New York City who reported opioid use in the past month and/or were currently in treatment for opioid use disorder...
November 14, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27846878/perceived-coercion-to-enter-treatment-among-involuntarily-and-voluntarily-admitted-patients-with-substance-use-disorders
#5
Anne Opsal, Øistein Kristensen, John Kåre Vederhus, Thomas Clausen
BACKGROUND: Perceived coercion is a sense of pressure related to the experience of being referred to treatment. The sense of pressure arises from the patient's internal perception of coercion. The sources of coercion may be the legal system, the family, the health system, or self-criticism (internal sources). Here, we studied patients diagnosed with substance use disorders that were involuntarily admitted to hospital, pursuant to a social services act. We sought to determine whether these patients perceived coercion differently than patients that were admitted voluntarily...
November 15, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27830625/substance-misuse
#6
(no author information available yet)
This literature review concerned the end of life care needs of patients with drug and alcohol addiction, particularly in the UK, and to identify existing good practice guidance. Three themes emerged: » The need to improve recognition of substance misuse in patients receiving palliative care, and to meet the challenges palliative care teams face when caring for patients who have current or past opiate, benzodiazepine or alcohol addictions. » A lack of UK literature addressing the end of life care needs of patients with drug and alcohol addiction...
November 10, 2016: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/27822137/axitinib-has-antiangiogenic-and-antitumorigenic-activity-in-myxoid-liposarcoma
#7
Lauren T Kerr, Jacqueline F Donoghue, Alexander L Wilding, Terrance G Johns
Myxoid liposarcoma is a rare form of soft-tissue sarcoma. Although most patients initially respond well to treatment, approximately 21% relapse, highlighting the need for alternative treatments. To identify novel treatment regimens and gain a better understanding of myxoid liposarcoma tumor biology, we screened various candidate and approved targeted therapeutics and chemotherapeutics against myxoid liposarcoma cell lines. Therapeutics that target angiogenesis showed antitumor activity. The small molecule inhibitor axitinib, which targets angiogenesis by inhibiting the VEGFR and PDGFR families and c-Kit, inhibited cell cycle progression and induced apoptosis in vitro, as well as having significant antitumor activity against MLS 1765 myxoid liposarcoma xenografts in mice...
2016: Sarcoma
https://www.readbyqxmd.com/read/27811289/challenges-in-engaging-parents-in-the-drug-and-alcohol-treatment-the-professionals-perspective
#8
Evdokia Misouridou, Danai Papadatou
Addiction treatment centers often fail to involve families in treatment. The aim of the present study was to explore the challenges that Greek mental health professionals encounter in their work with parents of drug and alcohol abusers. A qualitative study design was adopted, and five focus group discussions were conducted with 27 drug and alcohol professionals. The thematic analysis of their accounts revealed the key difficulties that professionals encounter in their collaboration with parents that included parental lack of involvement or over-engagement in treatment, unrealistic expectations, ambivalence or opposition to change, ethical dilemmas, and alliance issues, as well as collaboration challenges among therapists...
November 2, 2016: Qualitative Health Research
https://www.readbyqxmd.com/read/27803893/pathways-to-care-of-alcohol-dependent-patients-an-exploratory-study-from-a-tertiary-care-substance-use-disorder-treatment-center
#9
Yatan Pal Singh Balhara, Sathya Prakash, Rishab Gupta
BACKGROUND: No study from India has examined pathways to care in alcohol using population systematically. OBJECTIVES: The present study aimed to understand the pathways to care among alcohol-dependent individuals seeking help at a tertiary care center. PATIENTS AND METHODS: It was a cross-sectional, observational study. A total of 58 subjects diagnosed with alcohol- dependence syndrome as per DSM-IV-TR were included in the study. Pathways to care were assessed using the world health organization encounter form...
September 2016: International Journal of High Risk Behaviors & Addiction
https://www.readbyqxmd.com/read/27803891/a-qualitative-study-of-the-relationship-between-methamphetamine-abuse-and-sexual-dysfunction-in-male-substance-abusers
#10
Behrouz Dolatshahi, Ali Farhoudian, Mozhgan Falahatdoost, Mahmoud Tavakoli, Ebrahim Rezaie Dogahe
BACKGROUND: Increased prevalent use of methamphetamine is a global public challenge. Information on drug use can be helpful in preventing high-risk behavior related to drug abuse. OBJECTIVES: This study aims to investigate the sexual function changes related to methamphetamine use in the male clients of public and private addiction treatment centers. PATIENTS AND METHODS: In this qualitative study, 45 men (35 methamphetamine users, 5 family members of the users, and 5 psychiatrists or physicians who were famous for treating or researching addiction) are involved...
September 2016: International Journal of High Risk Behaviors & Addiction
https://www.readbyqxmd.com/read/27800208/family-based-intervention-program-for-parents-of-substance-abusing-youth-and-adolescents
#11
David Bisetto Pons, Remedios González Barrón, Álvaro Botella Guijarro
The use of drugs among adolescents/youth often results in a high degree of distress for the family members who live with them. This in turn can lead to a deterioration of mental (psychological) health, hindering any attempt to successfully cope with the situation. The goal of our research was to study the effect of the Community Reinforcement and Family Training (CRAFT) program on parents of adolescents/young adult drug users. Study volunteers (n = 50) were parents from Valencia (Spain) that were divided into two groups...
2016: Journal of Addiction
https://www.readbyqxmd.com/read/27783740/the-path-to-crack-addiction-perceptions-of-people-under-treatment
#12
Sheila Mara Pedrosa, Mary Lopes Reis, Daniela Tavares Gontijo, Sheila Araújo Teles, Marcelo Medeiros
Objective: the objective of this study was to understand the meaning of the harmful use of crack by people undergoing addiction treatment. Method: qualitative approach of social research on strategic modality was used. Field observation, preparation of field diary and focus groups, and data analysis through the method of interpreting meaning were carried out. Results: the results contributed to the construction of three thematic categories: "The discovery of crack and other drugs" that describes the experimentation with crack and other drugs; "The pain of the pleasure", key category that describes the moments after crack experimentation and that, many times, turns into addiction, which leads the person into a cycle of short periods of attempts at abstinence, relapse, and relentless consumption; and "Return to normal life"...
September 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27776680/medication-assisted-treatment-improves-child-permanency-outcomes-for-opioid-using-families-in-the-child-welfare-system
#13
Martin T Hall, Jordan Wilfong, Ruth A Huebner, Lynn Posze, Tina Willauer
Parents who use opioids and are involved in the child welfare system are less likely to retain custody of their children than parents who use other drugs. No previous studies have described medication-assisted treatment (MAT) utilization and child permanency outcomes for this population. The Sobriety Treatment and Recovery Team (START) model is a child welfare-based intervention focused on families with co-occurring substance use and child abuse / neglect issues. This study examined the prevalence and correlates of MAT utilization among parents in the START program with a history of opioid use, and compared child outcomes for families who received MAT services to those who did not...
December 2016: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/27766532/ehealth-intervention-for-problematic-internet-use-piu
#14
Lawrence T Lam, Mary K Lam
Excessive use of the Internet is considered a problematic behaviour by clinicians and researchers. Cognitive behaviour therapy (CBT) has been advocated for a long time as a treatment approach and has been extended to include family therapy in the recent years. As eTherapy (eHealth) has become an important component in the treatment of many mental health problems, it is prudent to explore the current status of the eHealth approach as an intervention option for this problem. This systematic review aims to examine the current development of online intervention programmes for this particular condition...
December 2016: Current Psychiatry Reports
https://www.readbyqxmd.com/read/27749976/adolescents-with-internet-gaming-disorder-igd-profiles-and-treatment-response
#15
María Martín-Fernández, Josep Lluís Matalí, Sara García-Sánchez, Marta Pardo, María Lleras, Carmina Castellano-Tejedor
Demand for treatment for problems related to the use of video games have increased significantly in adolescents. Most cases have a comorbid mental disorder that jeopardises both pathologies. The aim of this study is to describe profiles of adolescents with Internet Gaming Disorder (IGD) according to comorbidity and analyze treatment response at 3 and 6 months. A sample of 86 patients which consulted in the Addictive Behavior Unit of a hospital was assessed with diagnostic criteria for IGD, the interview K-SADS-PL for mental disorders and the Clinical Global Impression (CGI) to treatment progress...
September 29, 2016: Adicciones
https://www.readbyqxmd.com/read/27748296/use-of-family-cage-aid-questionnaire-to-screen-the-family-members-for-diagnosis-of-substance-dependence
#16
Debasish Basu, Abhishek Ghosh, Nandita Hazari, Preeti Parakh
BACKGROUND & OBJECTIVES: CAGE-AID questionnaire is a short, useful screening tool for substance dependence. Assessment of one family member for the screening of substance dependence in the family could be useful in clinical practice and research. In this study, we aimed to assess the validity of the Family CAGE-AID questionnaire for the diagnosis of substance dependence. METHODS: Cross-sectional assessments using CAGE-AID and Family CAGE-AID questionnaires were conducted both for the study participants (n = 210) and their family members...
June 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27747887/multi-family-therapy-with-a-reflecting-team-a-preliminary-study-on-efficacy-among-opiate-addicts-in-methadone-maintenance-treatment
#17
Miguel Garrido-Fernández, Juan A Marcos-Sierra, Ana López-Jiménez, Iñigo Ochoa de Alda
In this study, we evaluate the efficacy of multi-family therapy at reducing the addiction severity and at improving the psychological and family dynamics of opiate addicts receiving methadone treatment at a public treatment center. The study compares multi-family therapy with a reflecting team (MFT-RT) and a standard treatment following a methadone maintenance treatment program. The results show that multi-family therapy with a reflecting team effectively reduces the addiction severity in several of the areas evaluated and noted that this effect is superior to standard treatment...
October 17, 2016: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/27730727/impairment-of-opiate-mediated-behaviors-by-the-selective-trpv1-antagonist-sb366791
#18
Shi-Xun Ma, Seung-Hwan Kwon, Jee-Yeon Seo, Ji-Young Hwang, Sa-Ik Hong, Hyoung-Chun Kim, Seok-Yong Lee, Choon-Gon Jang
Transient receptor potential vanilloid type 1 (TRPV1), the archetypal member of the vanilloid TRP family, was initially identified as the receptor for capsaicin, the pungent ingredient in hot chili peppers. We previously demonstrated that TRPV1 in the dorsal striatum significantly contributes to morphine reward by using the conditioned place preference paradigm in mice; however, it is unknown whether TRPV1 has the same effect in other reward models. In this study, we investigated the role of TRPV1 in morphine reward by using a self-administration paradigm in rats...
October 11, 2016: Addiction Biology
https://www.readbyqxmd.com/read/27730106/impact-of-a-methadone-maintenance-program-on-an-aboriginal-community-a-qualitative-study
#19
Michel Landry, Nadia Veilleux, Julie-Eve Arseneault, Saneea Abboud, André Barrieau, Mathieu Bélanger
BACKGROUND: Methadone maintenance treatment programs implemented in Aboriginal communities have proven to be beneficial for the control of opioid addiction and its associated consequences, but the perceptions and opinions of different community members about these programs remain elusive. The goal of this study was to determine the perceptions of members of a First Nation community in New Brunswick, Canada, on the implementation of a methadone maintenance treatment program and its effects on the community...
July 2016: CMAJ Open
https://www.readbyqxmd.com/read/27729121/assessment-and-management-of-pain-in-pediatric-otolaryngology
#20
Maria Claudia Rodríguez, Perla Villamor, Tatiana Castillo
INTRODUCTION: Pain is a disease by itself and it's a public health concern of major implication in children, not just because of the emotional component of the child and his family, but also due to the potential morbidity and mortality involving it. A proper assessment of pain it's a challenge in the pediatric population, due to their lack of understanding and verbalization of hurt. Additionally, a satisfactory treatment of pediatric pain can be arduous due to a lack of clinical knowledge, insufficient pediatric research, and the fear to opioid side effects and addiction...
November 2016: International Journal of Pediatric Otorhinolaryngology
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