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https://www.readbyqxmd.com/read/28640845/is-self-assessment-of-medical-abortion-using-a-low-sensitivity-pregnancy-test-combined-with-a-checklist-and-phone-text-messages-feasible-in-south-african-primary-healthcare-settings-a-randomized-trial
#1
Deborah Constant, Jane Harries, Kristen Daskilewicz, Landon Myer, Kristina Gemzell-Danielsson
OBJECTIVE: To evaluate feasibility of self-assessment of medical abortion outcome using a low-sensitivity urine pregnancy test, checklist and text messages. The study assessed whether accurate self-assessment required a demonstration of the low-sensitivity urine pregnancy test or if verbal instructions suffice. METHODS: This non-inferiority trial enrolled 525 adult women from six public sector abortion clinics. Eligible women were undergoing medical abortion at gestations within 63 days...
2017: PloS One
https://www.readbyqxmd.com/read/28640723/intravitreal-injections-service-a-patient-experience-evaluation
#2
Hani Hasan, Sarah Flockhart, Waseem Qureshi, Selina Khan, Shahina Ahmed, Nimish Shah
INTRODUCTION: This survey has been conducted following the introduction of nurse-led intravitreal injections clinics at the Great Western Hospital. A team of 5 nurses regularly carry out an average of 90 injections per week. METHODS: A series of 169 consecutive injection patients have been offered the study questionnaire between 28 January 2016 and 28 February 2016; patients with no previous experience with a nurse injector were excluded. RESULTS: 76...
June 22, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28636866/prevalence-and-risk-factors-of-chlamydia-trachomatis-neisseria-gonorrhoeae-trichomonas-vaginalis-and-other-sexually-transmissible-infections-among-women-attending-antenatal-clinics-in-three-provinces-in-papua-new-guinea-a-cross-sectional-survey
#3
Lisa M Vallely, Pamela Toliman, Claire Ryan, Glennis Rai, Johanna Wapling, Carolyn Tomado, Savarina Huliafi, Gloria Munnull, Patricia Rarau, Suparat Phuanukoonnon, Handan Wand, Peter Siba, Glen D L Mola, John M Kaldor, Andrew J Vallely
Background Papua New Guinea (PNG) is estimated to have among the highest prevalences of HIV and sexually transmissible infections (STIs) of any Asia-Pacific country, and one of the highest burdens of maternal syphilis globally. The prevalence of curable STIs, such as Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV), among pregnant women in PNG is relatively unknown. METHODS: A cross-sectional bio-behavioural survey to investigate the epidemiology of CT, NG, TV and other STIs among pregnant women in three provinces of PNG was undertaken...
October 2016: Sexual Health
https://www.readbyqxmd.com/read/28636186/views-of-general-practice-staff-about-the-use-of-a-patient-oriented-treatment-decision-aid-in-shared-decision-making-for-patients-with-type-2-diabetes-a-mixed-methods-study
#4
Anita Wildeboer, Esther du Pon, Jan Schuling, Flora M Haaijer-Ruskamp, Petra Denig
BACKGROUND: Decision aids can be used to support shared decision making (SDM). A patient-oriented treatment decision aid (DA) was developed for type 2 diabetes but its use by general practice staff appeared to be limited. OBJECTIVES: To explore views of practice staff towards SDM and the DA. DESIGN: A mixed-methods study within the Dutch PORTDA-diab trial. SETTING AND PARTICIPANTS: Included were 17 practices with staff members who were responsible for routine diabetes care and had worked with the DA, and 209 of their patients...
June 21, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28633525/use-of-dimethyl-pimelimidate-with-microfluidic-system-for-nucleic-acids-extraction-without-electricity
#5
Choong Eun Jin, Tae Yoon Lee, Bonhan Koo, Kyung-Chul Choi, Suhwan Chang, Se Yoon Park, Ji Yeun Kim, Sung-Han Kim, Yong Shin
The isolation of nucleic acids in the lab on a chip is crucial to achieve the maximal effectiveness of point-of-care testing for detection in clinical applications. Here, we report on the use of a simple and versatile single-channel microfluidic platform that combines dimethyl pimelimidate (DMP) for nucleic acids (both RNA and DNA) extraction without electricity using thin films system. The system is based on the adaption of DMP into non-chaotropic-based nucleic acids and the capture of reagents into a low-cost thin film platform for use as a microfluidic total analysis system, which can be utilized for sample processing in clinical diagnostics...
June 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28633405/addressing-the-key-communication-barriers-between-microbiology-laboratories-and-clinical-units-a-qualitative-study
#6
Brita Skodvin, Karina Aase, Anita Løvås Brekken, Esmita Charani, Paul Christoffer Lindemann, Ingrid Smith
Background: Many countries are on the brink of establishing antibiotic stewardship programmes in hospitals nationwide. In a previous study we found that communication between microbiology laboratories and clinical units is a barrier to implementing efficient antibiotic stewardship programmes in Norway. We have now addressed the key communication barriers between microbiology laboratories and clinical units from a laboratory point of view. Methods: Qualitative semi-structured interviews were conducted with 18 employees (managers, doctors and technicians) from six diverse Norwegian microbiological laboratories, representing all four regional health authorities...
June 13, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28632867/effect-of-an-internet-based-program-on-weight-loss-for-low-income-postpartum-women-a-randomized-clinical-trial
#7
Suzanne Phelan, Todd Hagobian, Anna Brannen, Karen E Hatley, Andrew Schaffner, Karen Muñoz-Christian, Deborah F Tate
Importance: Postpartum weight retention increases lifetime risk of obesity and related morbidity. Few effective interventions exist for multicultural, low-income women. Objective: To test whether an internet-based weight loss program in addition to the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC program) for low-income postpartum women could produce greater weight loss than the WIC program alone over 12 months. Design, Setting, and Participants: A 12-month, cluster randomized, assessor-blind, clinical trial enrolling 371 adult postpartum women at 12 clinics in WIC programs from the California central coast between July 2011 and May 2015 with data collection completed in May 2016...
June 20, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28632479/use-and-acceptability-of-salivary-hepatitis-c-virus-testing-in-an-english-young-offender-institution
#8
Sophie Candfield, Mannampallil I Samuel, David Ritchie, Candice McDonald, Michael Brady, Chris Taylor
People held in prison are at a high risk of having hepatitis C virus (HCV) and there is a public health drive in the UK to increase HCV testing in prisons and Young Offender Institutions (YOIs), with opt-out testing. There is an oral antibody test for HCV; this project aims to determine its acceptability in an English YOI setting. This project offered HCV oral point-of-care testing (POCT) using the OraQuick® test to 107 male young offenders attending a sexual health service at an English YOI, monitoring HCV positivity and evaluating acceptability...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28631963/tumor-penetrating-peptide-integrated-thermally-sensitive-liposomal-doxorubicin-enhances-efficacy-of-radiofrequency-ablation-in-liver-tumors
#9
Fei Yan, Song Wang, Wei Yang, S Nahum Goldberg, Hao Wu, Wan-Lu Duan, Zhi-Ting Deng, Hai-Bo Han, Hai-Rong Zheng
Purpose To investigate the role of a tumor-penetrating peptide (internalizing CRGDRGPDC [iRGD])-integrated thermally sensitive liposomal (TSL) doxorubicin (DOX) in combination with radiofrequency (RF) ablation of liver tumors in an animal model. Materials and Methods Approval from the institutional animal care and use committee was obtained. Characterization of iRGD-TSL-DOX was performed in vitro. Next, H22 liver adenocarcinomas were implanted in 138 mice in vivo. The DOX accumulation and cell apoptosis of iRGD-TSL-DOX and TSL-DOX with or without RF were evaluated (n = 5) at different time points after treatment with quantitative analysis or pathologic staining...
June 19, 2017: Radiology
https://www.readbyqxmd.com/read/28631534/measuring-well-being-in-israel-and-palestine
#10
Guido Veronese, Alessandro Pepe, Jamal Dagdouke, Loredana Addimando, Shaher Yagi
This work presents the psychometric properties of the Subjective Well-Being Assessment Scale in a sample of 423 participants composed of Israeli Arabs and Palestinians from the West Bank/Gaza Strip. Psychometric assessment of the instrument was based on confirmatory factor analysis. The convergent and discriminant validity of Subjective Well-Being Assessment Scale were also tested via administration of the General Health Questionnaire and the Positive and Negative Affect Scale. The results suggest that Subjective Well-Being Assessment Scale is valid, reliable, and solid from a psychometric point of view and provides an accurate assessment of respondents' well-being...
January 1, 2017: Psychological Reports
https://www.readbyqxmd.com/read/28630417/ultrarapid-measurement-of-diagnostic-antibodies-by-magnetic-capture-of-immune-complexes
#11
Peter D Burbelo, Sreenivasulu Gunti, Jason M Keller, Caryn G Morse, Steven G Deeks, Michail S Lionakis, Amit Kapoor, Qingxue Li, Jeffrey I Cohen, Abner L Notkins, Ilias Alevizos
Rapid point-of-care, antibody-based testing is not currently available for the diagnosis of most autoimmune and infectious diseases. Here we report a simple, robust and ultrafast fluid-phase immunocapture method for clinical measurements of antibody levels. This method employs neodymium magnetic sticks that capture protein A/G-coated paramagnetic beads bound to antibody-luciferase-labeled antigen complexes. We demonstrate the ability to effectively measure specific antibody levels in serum samples from patients with varied infectious or autoimmune disorders, and in the case of Sjögren's syndrome directly in saliva, requiring about a minute per assay...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28627860/the-world-health-organization-disability-assessment-schedule-2-0-can-predict-the-institutionalization-of-the-patients-with-stroke
#12
Hsiang-Yueh Hu, Wen-Chou Chi, Kwang-Hwa Chang, Chia-Feng Yen, Reuben Escorpizo, Hua-Fang Liao, Shih-Wei Huang, Tsan-Hon Liou
BACKGROUND: The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is a well-known questionnaire used to evaluate disability. We can not only evaluate disability but also obtain additional information by using the standardized WHODAS 2.0 scores. AIM: To predict the institutionalization of the patients with stroke by using the standardized WHODAS 2.0 scores. DESIGN: Observational study. SETTING: The data of 10,255 patients with stroke were acquired from the Data Bank of Persons with Disabilities (TDPD) in Taiwan...
June 19, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28627254/randomized-trial-of-a-lifestyle-physical-activity-intervention-for-breast-cancer-survivors-effects-on-transtheoretical-model-variables
#13
Stacie Scruggs, Scherezade K Mama, Cindy L Carmack, Tommy Douglas, Pamela Diamond, Karen Basen-Engquist
This study examined whether a physical activity intervention affects transtheoretical model (TTM) variables that facilitate exercise adoption in breast cancer survivors. Sixty sedentary breast cancer survivors were randomized to a 6-month lifestyle physical activity intervention or standard care. TTM variables that have been shown to facilitate exercise adoption and progress through the stages of change, including self-efficacy, decisional balance, and processes of change, were measured at baseline, 3 months, and 6 months...
June 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28627110/patient-preferences-for-healthcare-delivery-through-community-pharmacy-settings-in-the-usa-a-discrete-choice-study
#14
M Feehan, M Walsh, J Godin, D Sundwall, M A Munger
WHAT IS KNOWN AND OBJECTIVE: In order to improve public health, it is necessary to facilitate patients' easy access to affordable high-quality primary health care, and one enhanced approach to do so may be to provide primary healthcare services in the community pharmacy setting. Discrete choice experiments to evaluate patient demand for services in pharmacy are relatively limited and have been hampered by a focus on only a few service alternatives, most focusing on changes in more traditional pharmacy services...
June 18, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28625445/prospective-double-blind-randomized-placebo-controlled-clinical-trial-of-the-pectoral-nerves-pecs-block-type-ii
#15
Barbara Versyck, Geert-Jan van Geffen, Patrick Van Houwe
STUDY OBJECTIVE: The aim of this clinical trial was to test the hypothesis whether adding the pectoral nerves (Pecs) block type II to the anesthetic procedure reduces opioid consumption during and after breast surgery. DESIGN: A prospective randomized double blind placebo-controlled study. SETTING: A secondary hospital. PATIENTS: 140 breast cancer stage 1-3 patients undergoing mastectomy or tumorectomy with sentinel node or axillary node dissection...
August 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28625299/managing-major-obstetric-haemorrhage-pharmacotherapy-and-transfusion
#16
REVIEW
Rachel Collis, Emilia Guasch
Major obstetric haemorrhage is a leading cause of maternal mortality. A prescriptive approach to early recognition and management is critical to improving outcomes. Uterine atony is the primary cause of post-partum haemorrhage. First-line prevention and treatment include the administration of uterine tonic agents; other conservative measures include uterine cavity tamponade and uterine compression sutures. Interventional radiology procedures have been used for both prophylaxis and treatment, but a hysterectomy may be necessary if conservative measures fail...
March 2017: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/28625262/-predictive-value-of-sofa-score-combined-agi-grading-system-in-elderly-patients-with-sepsis-a-retrospective-analysis-with-91-patients
#17
Lingling Wang, Rui Chen, Zexun Mo, Jiahui Dong, Zhaokun Sun, Fei Xiao, Shaoting Hu, Richeng Xiong, Jie Sun, Zhou Yu, Zhenhui Guo
OBJECTIVE: To explore the predictive value of sequential organ failure assessment (SOFA) score combined the acute gastrointestinal injury (AGI) grading system in critical elderly patients with sepsis. METHODS: A retrospective analysis was conducted. Elderly patients with sepsis aged > 60 years admitted to medical intensive care unit (MICU) of General Hospital of Guangzhou Military Command from March 2014 to December 2015 and experiencing critical care over 48 hours were enrolled...
February 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28625261/-formulation-of-combined-predictive-indicators-using-logistic-regression-model-in-predicting-sepsis-and-prognosis
#18
Liwei Duan, Sheng Zhang, Zhaofen Lin
OBJECTIVE: To explore the method and performance of using multiple indices to diagnose sepsis and to predict the prognosis of severe ill patients. METHODS: Critically ill patients at first admission to intensive care unit (ICU) of Changzheng Hospital, Second Military Medical University, from January 2014 to September 2015 were enrolled if the following conditions were satisfied: (1) patients were 18-75 years old; (2) the length of ICU stay was more than 24 hours; (3) All records of the patients were available...
February 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28625260/-predictive-value-of-four-different-scoring-systems-for-septic-patient-s-outcome-a-retrospective-analysis-with-311-patients
#19
Shengbiao Wang, Tao Li, Yunfeng Li, Jianwen Zhang, Xingui Dai
OBJECTIVE: To study the predicting value of four different scoring systems such as the acute physiology and chronic health evaluation II (APACHE II) score, sequential organ failure assessment (SOFA) score, quick SOFA (qSOFA) score and systemic inflammatory response syndrome (SIRS) score for the prognosis of septic patients. METHODS: A retrospective analysis were conducted. Septic patients in intensive care unit (ICU) of the First People's Hospital of Chenzhou form July 1st, 2012 to June 30th, 2016 were enrolled...
February 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28625256/-comparison-of-effect-of-norepinephrine-and-terlipressin-on-patients-with-ards-combined-with-septic-shock-a-prospective-single-blind-randomized-controlled-trial
#20
Zhi Chen, Ping Zhou, Yuanhua Lu, Chunli Yang
OBJECTIVE: To approach the effect of different vasopressor on hemodynamics, volume responsiveness, fluid volume balance, renal function and prognosis in patients with acute respiratory distress syndrome (ARDS) complicated with septic shock. METHODS: A prospective single-blind randomized controlled trial was conducted. ARDS patients with septic shock admitted to the Department of Critical Care Medicine of Jiangxi Provincial People's Hospital from January 1st, 2015 to May 1st, 2016 were enrolled...
February 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
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