keyword
MENU ▼
Read by QxMD icon Read
search

plant hypoxia

keyword
https://www.readbyqxmd.com/read/28332493/plant-cysteine-oxidases-are-dioxygenases-that-directly-enable-arginyl-transferase-catalysed-arginylation-of-n-end-rule-targets
#1
Mark D White, Maria Klecker, Richard J Hopkinson, Daan A Weits, Carolin Mueller, Christin Naumann, Rebecca O'Neill, James Wickens, Jiayu Yang, Jonathan C Brooks-Bartlett, Elspeth F Garman, Tom N Grossmann, Nico Dissmeyer, Emily Flashman
Crop yield loss due to flooding is a threat to food security. Submergence-induced hypoxia in plants results in stabilization of group VII ETHYLENE RESPONSE FACTORs (ERF-VIIs), which aid survival under these adverse conditions. ERF-VII stability is controlled by the N-end rule pathway, which proposes that ERF-VII N-terminal cysteine oxidation in normoxia enables arginylation followed by proteasomal degradation. The PLANT CYSTEINE OXIDASEs (PCOs) have been identified as catalysts of this oxidation. ERF-VII stabilization in hypoxia presumably arises from reduced PCO activity...
March 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28280927/cuticle-ultrastructure-cuticular-lipid-composition-and-gene-expression-in-hypoxia-stressed-arabidopsis-stems-and-leaves
#2
Hyojin Kim, Dongsu Choi, Mi Chung Suh
An increased permeability of the cuticle is closely associated with downregulation of genes involved in cuticular lipid synthesis in hypoxia-stressed Arabidopsis and may allow plants to cope with oxygen deficiency. The hydrophobic cuticle layer consisting of cutin polyester and cuticular wax is the first barrier to protect the aerial parts of land plants from environmental stresses. In the present study, we investigated the role of cuticle membrane in Arabidopsis responses to oxygen deficiency. TEM analysis showed that the epidermal cells of hypoxia-treated Arabidopsis stems and leaves possessed a thinner electron-translucent cuticle proper and a more electron-dense cuticular layer...
March 9, 2017: Plant Cell Reports
https://www.readbyqxmd.com/read/28259984/attenuation-of-prostaglandin-e1%C3%A2-induced-osteoprotegerin-synthesis-in-osteoblasts-by-normoxic-hif-inducers
#3
Gen Kuroyanagi, Haruhiko Tokuda, Naohiro Yamamoto, Shingo Kainuma, Kazuhiko Fujita, Reou Ohguchi, Rie Matsushima-Nishiwaki, Osamu Kozawa, Takanobu Otsuka
Mimosine, which is a natural plant amino acid present in the Leucaena genus, is able to induce hypoxia‑inducible factors (HIFs). Previous evidence has indicated that HIF regulates angiogenesis‑osteogenesis coupling in bone metabolism, and it has previously been reported that mimosine inhibits prostaglandin (PG)F2α‑induced osteoprotegerin (OPG) synthesis without affecting interleukin‑6 (IL‑6) production in osteoblast‑like MC3T3‑E1 cells. In addition, PGE1 has been demonstrated to induce OPG synthesis via activation of p38 mitogen‑activated protein (MAP) kinase and stress‑activated protein kinase/c‑Jun N‑terminal kinase (SAPK/JNK) in these cells, and PGE1 stimulates IL‑6 production via the activation of protein kinase A...
February 8, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28192241/molecular-cloning-mrna-expression-and-characterization-of-membrane-bound-hemoglobin-in-oriental-river-prawn-macrobrachium-nipponense
#4
Shengming Sun, Fujun Xuan, Hongtuo Fu, Jian Zhu, Xianping Ge, Xugan Wu
Most hemoglobins are respiratory proteins and are ubiquitous in animals, bacteria, fungi, protists, and plants. In this study, we describe a membrane-bound hemoglobin in the oriental river prawn Macrobrachium nipponense (MnHb), which also expresses hemocyanin. MnHb cDNA was cloned using the rapid amplification of cDNA ends (RACE) approach, which afforded a 1201bp gene encoding a 193 amino acid polypeptide. Bioinformatic evaluation suggested MnHb is membrane anchored by N-myristoylation, and immunofluorescence confirmed its location in the membrane of chief cells in the gill...
February 10, 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/28163970/garcinia-subelliptica-merr-fukugi-a-multipurpose-coastal-tree-with-promising-medicinal-properties
#5
REVIEW
Tomomi Inoue, Mami Kainuma, Karin Baba, Nozomi Oshiro, Norimi Kimura, Eric Wei Chiang Chan
In this short review, the current knowledge on the botany, ecology, uses, and medicinal properties of the multipurpose Garcinia subelliptica (Fukugi) is updated. As yet, there are no reviews on this indigenous and heritage coastal tree species of the Ryukyu Islands in Japan, which has ethnocultural, ecological, and pharmacological significance. Planted by the Okinawan people some 300 years ago, Fukugi trees serve as windbreaks and accord protection against the destructive typhoons. The species has become a popular ornamental tree, and its bark has been used for dyeing fabrics...
January 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28120710/the-role-of-universal-stress-proteins-in-bacterial-infections
#6
Andrew O Connor, Siobhán McClean
Universal stress proteins are ubiquitously expressed in bacteria, archaea and plants and other eukaryotes. A general property of USPs is their role in adaptation of bacteria to oxidative stress, high temperature, low pH and/or hypoxia. There is increasing evidence that these proteins facilitate the adaption of bacterial pathogens to the human host environment, thereby facilitating colonisation and pathogenicity. USPs in Mycobacterium tuberculosis are well studied and may play a role in latency of tuberculosis...
January 24, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28110268/metabolic-and-physiological-adjustment-of-suaeda-maritima-to-combined-salinity-and-hypoxia
#7
Jan H Behr, Alain Bouchereau, Solenne Berardocco, Charlotte E Seal, Timothy J Flowers, Christian Zörb
BACKGROUND AND AIMS: Suaeda maritima is a halophyte commonly found on coastal wetlands in the intertidal zone. Due to its habitat S. maritima has evolved tolerance to high salt concentrations and hypoxic conditions in the soil caused by periodic flooding. In the present work, the adaptive mechanisms of S. maritima to salinity combined with hypoxia were investigated on a physiological and metabolic level. METHODS: To compare the adaptive mechanisms to deficient, optimal and stressful salt concentrations, S...
January 20, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28107563/are-commercial-sweet-cherry-rootstocks-adapted-to-climate-change-short-term-waterlogging-and-co2-effects-on-sweet-cherry-cv-burlat
#8
Margarita Pérez-Jiménez, María Hernández-Munuera, M Carmen Piñero, Gregorio López-Ortega, Francisco M Del Amor
High CO2 is able to ameliorate some negative effects due to climate change and intensify others. This study involves the sweet cherry (Prunus avium) cultivar 'Burlat' grafted on the 'Mariana 2624', 'Adara' and 'LC 52' rootstocks. In a climate chamber at two CO2 concentrations: ambient (400 µmol mol(-1) ) and elevated (800 µmol mol(-1) ), the plants were submitted to waterlogging for seven days, followed by seven days of recovery after drainage. Waterlogging drastically decreased the rate of photosynthesis, significantly endangering plant survival, particularly for the 'LC 52' and 'Adara' rootstocks...
January 20, 2017: Plant, Cell & Environment
https://www.readbyqxmd.com/read/28104392/scutellarein-antagonizes-the-tumorigenesis-by-modulating-cytokine-vegf-mediated-neoangiogenesis-and-dff-40-actuated-nucleosomal-degradation
#9
Prabhu Thirusangu, V Vigneshwaran, B R Vijay Avin, H Rakesh, H M Vikas, B T Prabhakar
Neoplastic cells often reside in distinctive tumor hypoxia armed with a series of adaptive responses including oxidative stress, defective apoptotic machinery and neoangiogenesis, through that further confer cell survival improvement. Plants still acts as reservoir of natural chemicals to provide newer active pharmacophores. Scutellarein is flavones which has wide range of pharmacophoral effects. In our current research, scutellarein employed for targeting oxidative stress mediated tumor angiogenesis and apoptotic nuclear fragmentation...
February 26, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28087771/genome-wide-convergence-during-evolution-of-mangroves-from-woody-plants
#10
Shaohua Xu, Ziwen He, Zixiao Guo, Zhang Zhang, Gerald J Wyckoff, Anthony Greenberg, Chung-I Wu, Suhua Shi
When living organisms independently invade a new environment, the evolution of similar phenotypic traits is often observed. An interesting but contentious issue is whether the underlying molecular biology also converges in the new habitat. Independent invasions of tropical intertidal zones by woody plants, collectively referred to as mangrove trees, represent some dramatic examples. The high salinity, hypoxia and other stressors in the new habitat might have affected both genomic features and protein structures...
January 12, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28079178/significance-of-oxygen-transport-through-aquaporins
#11
Janusz J Zwiazek, Hao Xu, Xiangfeng Tan, Alfonso Navarro-Ródenas, Asunción Morte
Aquaporins are membrane integral proteins responsible for the transmembrane transport of water and other small neutral molecules. Despite their well-acknowledged importance in water transport, their significance in gas transport processes remains unclear. Growing evidence points to the involvement of plant aquaporins in CO2 delivery for photosynthesis. The role of these channel proteins in the transport of O2 and other gases may also be more important than previously envisioned. In this study, we examined O2 permeability of various human, plant, and fungal aquaporins by co-expressing heterologous aquaporin and myoglobin in yeast...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28072536/role-of-ionic-strength-and-ph-in-modulating-thermodynamic-profiles-associated-with-co-escape-from-rice-nonsymbiotic-hemoglobin-1
#12
David Butcher, Sophie Bernad, Valerie Derrien, Pierre Sebban, Jaroslava Miksovska
Type 1 nonsymbiotic hemoglobins are found in a wide variety of land plants and exhibit very high affinities for exogenous gaseous ligands. These proteins are presumed to have a role in protecting plant cells from oxidative stress under etiolated/hypoxic conditions through NO dioxygenase activity. In this study we have employed photoacoustic calorimetry, time-resolved absorption spectroscopy, and classical molecular dynamics simulations in order to elucidate thermodynamics, kinetics, and ligand migration pathways upon CO photodissociation from WT and a H73L mutant of type 1 nonsymbiotic hemoglobin from Oryza sativa (rice)...
January 19, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28068279/identifying-predictors-of-central-sleep-apnea-cheyne-stokes-breathing-in-chronic-heart-failure-a-pathophysiological-approach
#13
Aneliya I Draganova, Kiril V Terziyski, Stefan S Kostianev
Chronic heart failure (CHF) is a major health problem associated with increased mortality, despite modern treatment options. Central sleep apnea (CSA)/Cheyne-Stokes breathing (CSB) is a common and yet largely under-diagnosed co-morbidity, adding significantly to the poor prognosis in CHF because of a number of acute and chronic effects, including intermittent hypoxia, sympathetic overactivation, disturbed sleep architecture and impaired physical tolerance. It is characterized by repetitive periods of crescendo-decrescendo ventilatory pattern, alternating with central apneas and hypopneas...
December 1, 2016: Folia Medica
https://www.readbyqxmd.com/read/28029095/sumoylation-of-nav1-2-channels-mediates-the-early-response-to-acute-hypoxia-in-central-neurons
#14
Leigh D Plant, Jeremy D Marks, Steve An Goldstein
The mechanism for the earliest response of central neurons to hypoxia-an increase in voltage-gated sodium current (INa)-has been unknown. Here, we show that hypoxia activates the Small Ubiquitin-like Modifier (SUMO) pathway in rat cerebellar granule neurons (CGN) and that SUMOylation of NaV1.2 channels increases INa. The time-course for SUMOylation of single NaV1.2 channels at the cell surface and changes in INa coincide, and both are prevented by mutation of NaV1.2-Lys38 or application of a deSUMOylating enzyme...
December 28, 2016: ELife
https://www.readbyqxmd.com/read/28010170/are-avoidance-and-acclimation-responses-during-hypoxic-stress-modulated-by-distinct-cell-specific-mechanisms
#15
Mohamed M Mira, Eman A El-Khateeb, Hannan I SayedAhmed, Robert D Hill, Claudio Stasolla
Plants respond to hypoxic stress through either acclimation to the stress or avoidance of it, as they do to most environmental stresses. The hypothesis that has general consensus among the community is that ethylene response factors (ERFs) are central elements that control both types of responses to hypoxia. Recent studies suggest that this may not be the case for all cells experiencing hypoxic stress. Mature maize root cells undergoing hypoxic stress were found to undergo acclimation and avoidance mechanisms involving ERFs, whereas meristematic root cells and cells still undergoing differentiation acclimated to the response without the involvement of ethylene synthesis or ERFs...
January 2, 2017: Plant Signaling & Behavior
https://www.readbyqxmd.com/read/27995331/erf73-hre1-is-involved-in-h2o2-production-via-hypoxia-inducible-rboh-gene-expression-in-hypoxia-signaling
#16
Chin-Ying Yang, Yi-Chun Huang, Shang-Ling Ou
Hypoxia deprives cells of energy and induces severe physical damage in embryophytes. Under hypoxia, the equilibrium between ethylene and H2O2 affects the response of the transcription factor AtERF73/HRE1. To evaluate the role of AtERF73/HRE1 during hypoxia signaling, we used three independent AtERF73/HRE1 knockout lines to detect H2O2 accumulation. The results revealed that under hypoxia, H2O2 accumulation in the AtERF73/HRE1 knockout lines decreased, indicating that AtERF73/HRE1 uses a negative feedback regulation mechanism to influence the production of H2O2 induced through hypoxia signal transduction...
December 19, 2016: Protoplasma
https://www.readbyqxmd.com/read/27994500/resveratrol-alleviate-hypoxic-pulmonary-hypertension-via-anti-inflammation-and-anti-oxidant-pathways-in-rats
#17
Dunquan Xu, Yan Li, Bo Zhang, Yanxia Wang, Yi Liu, Ying Luo, Wen Niu, Mingqing Dong, Manling Liu, Haiying Dong, Pengtao Zhao, Zhichao Li
Resveratrol, a plant-derived polyphenolic compound and a phytoestrogen, was shown to possess multiple protective effects including anti-inflammatory response and anti-oxidative stress. Hypoxic pulmonary hypertension (HPH) is a progressive disease characterized by sustained vascular resistance and marked pulmonary vascular remodeling. The exact mechanisms of HPH are still unclear, but inflammatory response and oxidative stress was demonstrated to participate in the progression of HPH. The present study was designed to investigate the effects of resveratrol on HPH development...
2016: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/27991916/the-hif-phf8-ar-axis-promotes-prostate-cancer-progression
#18
D Tong, Q Liu, G Liu, W Yuan, L Wang, Y Guo, W Lan, D Zhang, S Dong, Y Wang, H Xiao, J Mu, C Mao, J Wong, J Jiang
Recent studies provide strong evidence that the androgen receptor (AR) signaling pathway remains active in castration-resistant prostate cancer (CRPC). However, the underlying mechanisms are not well understood. In this study, we demonstrate that plant homeo domain finger protein 8 (PHF8 )interacts with and functions as an essential histone demethylase activity-dependent AR coactivator. Furthermore, we demonstrate that the expression of PHF8 is induced by hypoxia in various prostate cancer cell lines. Knockdown of either hypoxia-inducible factor HIF2α or HIF1α almost completely abolished hypoxia-induced PHF8 expression...
December 19, 2016: Oncogenesis
https://www.readbyqxmd.com/read/27986423/learning-to-breathe-developmental-phase-transitions-in-oxygen-status
#19
REVIEW
Michael J Considine, Pedro Diaz-Vivancos, Pavel Kerchev, Santiago Signorelli, Patricia Agudelo-Romero, Daniel J Gibbs, Christine H Foyer
Plants are developmentally disposed to significant changes in oxygen availability, but our understanding of the importance of hypoxia is almost entirely limited to stress biology. Differential patterns of the abundance of oxygen, nitric oxide ((•)NO), and reactive oxygen species (ROS), as well as of redox potential, occur in organs and meristems, and examples are emerging in the literature of mechanistic relationships of these to development. We describe here the convergence of these cues in meristematic and reproductive tissues, and discuss the evidence for regulated hypoxic niches within which oxygen-, ROS-, (•)NO-, and redox-dependent signalling curate developmental transitions in plants...
February 2017: Trends in Plant Science
https://www.readbyqxmd.com/read/27956097/binding-studies-and-biological-evaluation-of-%C3%AE-carotene-as-a-potential-inhibitor-of-human-calcium-calmodulin-dependent-protein-kinase-iv
#20
Huma Naz, Parvez Khan, Mohd Tarique, Safikur Rahman, Abha Meena, Shahzaib Ahamad, Suaib Luqman, Asimul Islam, Faizan Ahmad, Md Imtaiyaz Hassan
Human calcium/calmodulin-dependent protein kinase IV (CAMKIV), a member of Ser/Thr kinase family, is associated with cancer, cerebral hypoxia and neurodegenerative diseases. β-carotene is a colored organic compound, abundant in plants and fruits and is used in cancer prevention. Here, we report a strong binding affinity of β-carotene with CAMKIV using molecular docking, fluorescence binding and isothermal titration calorimetry methods. Furthermore, β-carotene also reduces the enzyme activity of CAMKIV moderately as observed during ATPase assay...
December 9, 2016: International Journal of Biological Macromolecules
keyword
keyword
65066
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"