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https://www.readbyqxmd.com/read/29223603/factors-predicting-quality-of-life-and-societal-participation-after-survival-of-a-cardiac-arrest-a-prognostic-longitudinal-cohort-study
#1
Daan Verberne, Veronique Moulaert, Jeanine Verbunt, Caroline van Heugten
AIM: For those patients who suffer unfavourable outcome after survival of cardiac arrest, it is important to know whether this can be predicted at an early stage. Support can subsequently be provided. This study aimed to identify early prognostic factors of quality of life (QOL) and societal participation at one year post-cardiac arrest. METHODS: The design was a prospective longitudinal cohort study following cardiac arrest survivors up to one year. Prognostic personal, injury-related, function-related and subjective outcome factors were selected and entered into a hierarchical regression model to assess whether they were predictive of QOL and societal participation at one year post-cardiac arrest...
December 6, 2017: Resuscitation
https://www.readbyqxmd.com/read/29223602/prognostic-significance-of-shockable-and-non-shockable-cardiac-arrest-in-st-segment-elevation-myocardial-infarction-patients-undergoing-primary-angioplasty
#2
Nevio Taglieri, Francesco Saia, Maria Letizia Bacchi Reggiani, Gabriele Ghetti, Antonio Giulio Bruno, Claudia Rosetti, Matteo Bruno, Anna Corsini, Paola Battistini, Gianluca Lanati, Maria Teresa Di Dio, Diego Della Riva, Miriam Compagnone, Cinzia Marrozzini, Claudio Rapezzi
OBJECTIVE: To determine, in patients with ST-segment Elevation Myocardial Infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI), the prognostic weight of cardiac arrest (CA) according to the type of rhythm (shockable vs. non-shockable). METHODS: We prospectively enrolled 3278 consecutive STEMI patients undergoing PPCI. Multivariable Cox regression was used to establish the relation to 1-year cardiac mortality of both type of CA. In patients suffering from CA we identified predictors of both poor neurological outcome (cerebral performance categories 3-5) and cardiac mortality at 1year...
December 6, 2017: Resuscitation
https://www.readbyqxmd.com/read/29223525/case-series-of-rare-thymoma-metastases-to-the-spine-and-complete-literature-review
#3
Rebecca L Achey, Bryan S Lee, Swetha Sundar, Edward C Benzel, Ajit A Krishnaney
BACKGROUND: We report a series of three cases of metastatic thymoma to the spine with spinal cord compression. An extensive literature review of thymic metastases to the spine was completed in order to provide a comprehensive appraisal of current prognostic indicators and potential treatment algorithms to help guide clinicians in treatment management. CASE DESCRIPTIONS: Between 2000 and 2017, three patients were diagnosed with thymic metastases to the spine at our institution...
December 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29220331/regenerative-potential-of-secretome-from-dental-stem-cells-a-systematic-review-of-preclinical-studies
#4
Suleiman Alhaji Muhammad, Norshariza Nordin, Sharida Fakurazi
Injury to tissues is a major clinical challenge due to the limited regenerative capacity of endogenous cells. Stem cell therapy is evolving rapidly as an alternative for tissue regeneration. However, increasing evidence suggests that the regenerative ability of stem cells is mainly mediated by paracrine actions of secretome that are generally secreted by the cells. We aimed to systematically evaluate the efficacy of dental stem cell (DSC)-conditioned medium in in vivo animal models of various tissue defects...
December 8, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/29218822/european-academy-of-neurology-european-stroke-organisation-consensus-statement-and-practical-guidance-for-pre-hospital-management-of-stroke
#5
A Kobayashi, A Czlonkowska, G A Ford, A C Fonseca, G J Luijckx, J Korv, N Pérez de la Ossa, C Price, D Russell, A Tsiskaridze, M Messmer-Wullen, J De Keyser
Reduction of delay between onset and hospital arrival and adequate pre-hospital care of persons with acute stroke are important for improving chances of a favorable outcome. The objective is to recommend evidence-based practices for the management of patients with suspected stroke in the pre-hospital setting. The GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology was used to define the key clinical questions. An expert panel then reviewed the literature, established the quality of the evidence, and made recommendations...
December 7, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29218262/neurologic-outcomes-following-care-in-the-pediatric-intensive-care-unit
#6
Sherrill D Caprarola, Sapna R Kudchadkar, Melania M Bembea
Purpose of review: With increasing survival of children requiring admission to pediatric intensive care units (PICU), neurodevelopmental outcomes of these patients are an area of increased attention. Our goal was to systematically review recently published literature on neurologic outcomes of PICU patients. Recent Findings: Decline in neurofunctional status occurs in 3%-20% of children requiring PICU care. This proportion varies based on primary diagnosis and severity of illness, with children admitted for primary neurologic diagnosis, children who suffer cardiac arrest or who require invasive interventions during the PICU admission, having worse outcomes...
September 2017: Current Treatment Options in Pediatrics
https://www.readbyqxmd.com/read/29217485/developmental-origins-of-adult-health-and-disease-the-metabolic-role-of-bdnf-from-early-life-to-adulthood
#7
REVIEW
Despina D Briana, Ariadne Malamitsi-Puchner
Accumulating evidence suggests that the origins of adult disease may occur during fetal life. Thus, the concept of "developmental programming" has been introduced and supported by epidemiological and experimental data. This concept supports the idea that the nutritional and hormonal status during pregnancy could interfere in metabolism control. The mechanisms responsible for this "developmental programming" remain poorly documented. Current research indicates that neurotrophins and particularly brain-derived neurotrophic factor (BDNF) may play a crucial role in this process...
December 4, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29214598/evaluation-of-a-wireless-portable-wearable-multi-parameter-vital-signs-monitor-in-hospitalized-neurological-and-neurosurgical-patients
#8
Robert S Weller, Kristina L Foard, Timothy N Harwood
Unrecognized changes in patients' vital signs can result in preventable deaths in hospitalized patients. Few publications or studies instituting routine patient monitoring have described implementation and the setting of alarm parameters for vital signs. We wanted to determine if continuous multi-parameter patient monitoring can be accomplished with an alarm rate that is acceptable to hospital floor nurses and to compare the rate of patient deterioration events to those observed with routine vital sign monitoring...
December 6, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29214122/peripheral-nerve-sheath-tumors-of-the-upper-extremity-and-hand-in-patients-with-neurofibromatosis-type-1-topography-of-tumors-and-evaluation-of-surgical-treatment-in-62-patients
#9
Reinhard E Friedrich, Caroline Diekmeier
Objective: Neurofibromatosis type 1 (NF1) is an autosomal dominant tumor predisposition syndrome with a tendency to develop peripheral nerve sheath tumors (PNST). Plexiform neurofibromas (PNF) are detected in a high proportion of affected patients. The tumors can lead to severe disfigurement and are classified as precancerous. This study examines the surgical procedures that have been performed on large PNST of the upper limb and hand, and investigates whether a specific distribution pattern of the tumors can be detected in surgically treated cases...
2017: GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW
https://www.readbyqxmd.com/read/29213515/rehabilitation-in-severe-memory-deficit-a-case-study
#10
Nariana Mattos Figueiredo Sousa
The term amnesia refers to a pathological state of mind in which memory and learning are affected to a greater extent than other cognitive functions in a patient without altered level of consciousness. The aim of the current study was to describe a case of severe amnesia in a patient during neurological rehabilitation and to report the importance of preserved cognitive functions to compensate for the mnemonic deficit. VJA presented a clinical condition suggestive of encephalopathy due to caloric-protein malnutrition following several abdominal surgical procedures for complicated choledocholithiasis...
April 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29213212/implementation-and-feasibility-of-the-stroke-nursing-guideline-in-the-care-of-patients-with-stroke-a-mixed-methods-study
#11
Ingibjörg Bjartmarz, Helga Jónsdóttir, Thóra B Hafsteinsdóttir
Background: Nurses often have difficulties with using interdisciplinary stroke guidelines for patients with stroke as they do not focus sufficiently on nursing. Therefore, the Stroke Nursing Guideline (SNG) was developed and implemented. The aim of this study was to determine the implementation and feasibility of the SNG in terms of changes in documentation and use of the guideline in the care of stroke patients on Neurological and Rehabilitation wards, barriers and facilitators, and nurses' and auxiliary nurses' view of the implementation...
2017: BMC Nursing
https://www.readbyqxmd.com/read/29210906/temperature-management-for-out-of-hospital-cardiac-arrest
#12
Patrick J Coppler, Cameron Dezfulian, Jonathan Elmer, Jon C Rittenberger
More than 300,000 Americans suffer a cardiac arrest outside of the hospital each year and even among those who are successfully resuscitated and survive to hospital admission, outcomes remain poor. Temperature management (previously known as therapeutic hypothermia) is the only intervention that has been reproducibly demonstrated to ameliorate the neurologic injury that follows cardiac arrest. The results of a recent large randomized controlled trial have highlighted the uncertainty about temperature management strategies following cardiac arrest...
December 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/29210354/neurocysticercosis-among-people-living-nearby-pigs-heavily-infected-with-cysticercosis-in-rural-endemic-peru
#13
Brian T Garvey, Luz M Moyano, Viterbo Ayvar, Silvia Rodriguez, Robert H Gilman, Armando E Gonzalez, Hector H Garcia, Seth E O'Neal, For The Cysticercosis Working Group In Peru
Neurocysticercosis causes substantial neurologic morbidity in endemic regions around the world. In this cross-sectional study, we describe the frequency of neurocysticercosis among a presumed high-risk group of people in an endemic community in northern Peru. Participants who screened positive on a nine-question seizure survey were evaluated clinically to diagnose epilepsy using International League Against Epilepsy criteria. Those with epilepsy were offered a noncontrast computerized tomography (CT) of the head...
December 4, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29209539/proposing-development-and-utility-of-a-mobility-composite-measure-in-patients-with-a-neurologic-disorder
#14
Chad Swank, Sattam Almutairi, Ann Medley
Background: Outcome measures typically assess single domains making holistic assessment difficult. Our purpose was to develop a mobility composite measure (MCM) based on four commonly used outcome measures and compare this composite score to the individual measures in patients with neurologic disorders. Methods: We retrospectively reviewed 148 medical records for inclusion of primary neurologic diagnosis and scoring for 5 times sit-to-stand test (5TSST), 10-meter walk test (10MWT), 2-minute walk test (2MWT), and activities-specific balance confidence (ABC) scale...
2017: Rehabilitation Research and Practice
https://www.readbyqxmd.com/read/29209163/voluntary-ambulation-by-upper-limb-triggered-hal%C3%A2-in-patients-with-complete-quadri-paraplegia-due-to-chronic-spinal-cord-injury
#15
Yukiyo Shimizu, Hideki Kadone, Shigeki Kubota, Kenji Suzuki, Tetsuya Abe, Tomoyuki Ueno, Yuichiro Soma, Yoshiyuki Sankai, Yasushi Hada, Masashi Yamazaki
Patients with complete paraplegia after spinal cord injury (SCI) are unable to stand or walk on their own. Standing exercise decreases the risk of decubitus ulcers, osteoporosis, and joint deformities in patients with SCI. Conventional gait training for complete paraplegia requires excessive upper limb usage for weight bearing and is difficult in cases of complete quadriplegia. The purpose of this study was to describe voluntary ambulation triggered by upper limb activity using the Hybrid Assistive Limb® (HAL) in patients with complete quadri/paraplegia after chronic SCI...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29208017/a-multisession-evaluation-of-an-adaptive-competitive-arm-rehabilitation-game
#16
Maja Goršič, Imre Cikajlo, Nika Goljar, Domen Novak
BACKGROUND: People with neurological injuries such as stroke should exercise frequently and intensely to regain their motor abilities, but are generally hindered by lack of motivation. One way to increase motivation in rehabilitation is through competitive exercises, but such exercises have only been tested in single brief sessions and usually did not adapt difficulty to the patient's abilities. METHODS: We designed a competitive arm rehabilitation game for two players that dynamically adapts its difficulty to both players' abilities...
December 6, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29204485/arthroprosthetic-cobaltism-associated-with-cardiomyopathy
#17
Ryan S Charette, Alexander L Neuwirth, Charles L Nelson
Systemic cobaltism related to metal-on-metal total hip arthroplasty has been published in case reports and series with effects on the cardiac, neurologic, endocrine, and immunologic systems. This case report presents a 46-year-old male who underwent bilateral metal-on-metal total hip arthroplasty and subsequently developed cardiomyopathy requiring left ventricular assist device implantation. Intervention with bilateral revision to non-cobalt-containing implants resulted in improved cardiac function. This case report will alert clinicians to the presentation of this rare but devastating complication while also displaying improvement following revision total hip arthroplasty...
December 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/29204193/management-and-outcome-analysis-of-pediatric-unstable-thoracolumbar-spine-injury-large-surgical-series-with-literature-review
#18
REVIEW
Guru Dutta Satyarthee, M Sangani, Sumit Sinha, Deepak Agrawal
Pediatric thoracolumbar spine fractures are considered rare injuries with paucity of publication across the globe. Further, spine injuries in children are comparatively rarer, and pediatric spine differs from adults, both biomechanically and anatomically; so, adult spine management strategy cannot be applied to pediatric cases, and exact guidelines for management of pediatric spinal injury is lacking. The current study is undertaken to study epidemiology, surgical management, and outcome of pediatric dorsolumbar unstable spine injury...
July 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29204183/evaluation-of-outcomes-for-psychosis-and-epilepsy-treatment-delivered-by-primary-health-care-workers-in-nepal-a-cohort-study
#19
M J D Jordans, L Aldridge, N P Luitel, F Baingana, B A Kohrt
Background: Most evaluations of task-shifting have focused on common mental disorders. Much less work has been done on severe mental neurological and substance use (MNS) disorders, such as chronic psychosis and epilepsy. Given the high burden associated with severe MNS and the lack of mental health professionals in low and middle income countries, evaluations on the impact of task-shifting for these disorders are important. Methods: In a rural district of Nepal, a community mental health program, based on World Health Organization's Mental Health Gap Action Programme guidelines, was evaluated using a cohort study design...
2017: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/29203503/multicentre-prospective-randomised-single-blind-controlled-study-protocol-of-the-effect-of-an-additional-parent-administered-sensorimotor-stimulation-on-neurological-development-of-preterm-infants-primebrain
#20
Karine Pelc, Irit Daniel, Bernard Wenderickx, Bernard Dan
INTRODUCTION: Preterm and very low birthweight infants are at increased risk for neurodevelopmental disorders, including cerebral palsy, sensory impairment and intellectual disability. Several early intervention approaches have been designed in the hope of optimising neurological development in this context. It seems important that the intervention takes into account parental mental health, focuses on parent-child interactions and lasts sufficiently long. This study aims to evaluate the effects of a stimulation programme administered by parents until 6 months post-term on motor and neurophysiological development of infants born preterm...
December 3, 2017: BMJ Open
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