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https://www.readbyqxmd.com/read/29244126/silent-cerebral-small-vessel-disease-twice-as-prevalent-in-middle-aged-well-controlled-cart-treated-hiv-infected-individuals-than-hiv-uninfected-individuals
#1
Antoine Moulignier, Julien Savatovsky, Lambert Assoumou, François-Xavier Lescure, Cédric Lamirel, Ophelia Godin, Nadia Valin, Roland Tubiana, Ana Canestri, Pascal Roux, Jean-Claude Sadik, Laurence Salomon, Marie Abrivard, Christine Katlama, Yazdan Yazdanpanah, Gilles Pialoux, Pierre-Marie Girard, Dominique Costagliola
Background: Silent cerebral small-vessel disease (CSVD) is defined as white matter hyperintensities, silent brain infarction or microbleeds. CSVD is responsible for future vascular events, cognitive impairment, frailty and shorter survival. CSVD prevalence among middle-aged persons living with well-controlled HIV infection (PLHIVs) is unknown. Methods: ANRS EP51 MicroBREAK (NCT02082574) is a cross-sectional study with prospective enrollment of treated PLHIVs, ≥50 years old with viral load controlled for ≥12 months, and frequency age- and sex-matched HIV-uninfected controls (HUCs)...
December 13, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29243867/factors-for-incomplete-adherence-to-antiretroviral-therapy-including-drug-refill-and-clinic-visits-among-older-adults-living-with-hiv-cross-sectional-study-in-south-africa
#2
Abbie Barry, Nathan Ford, Ziad El-Khatib
OBJECTIVES: To assess adherence outcomes to antiretroviral therapy (ART) of recipients ≥50 years in Soweto, South Africa. METHODS: This was a secondary data analysis for a cross-sectional study at two HIV clinics in Soweto. Data on ART adherence and covariates were gathered through structured interviews with HIV 878 persons living with HIV (PLHIV) receiving ART. Logistic regression analysis was used to assess associations. RESULTS: PLHIV ≥50 years (n=103) were more likely to miss clinic visits during the last six months than PLHIV aged 25 - 49 years (OR 2...
December 15, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29243537/migration-and-health-at-older-age-in-rural-malawi
#3
Jacob Kendall, Philip Anglewicz
The connection between migration and health has long been established, but relatively little is known about this relationship for older persons, particularly in sub-Saharan Africa (SSA). In this paper, we examine migration selection with regards to health status among older individuals in Malawi, by testing whether older migrants differ from non-migrants in health status before migration. To do so, we use data from the Malawi Longitudinal Study of Families and Health, a longitudinal panel dataset that includes a relatively large number of individuals at older ages...
December 15, 2017: Global Public Health
https://www.readbyqxmd.com/read/29243012/use-of-a-unique-farmers-market-program-targeting-lower-income-community-members
#4
Brittany Lawrence, Anna E Greer, Anne Marie Zimeri, Daphne C Hernandez, SangNam Ahn, Shaakira Jones, Matthew Lee Smith
We examined use of a farmers' market that leverages community partnerships to provide free produce to lower-income persons. Participants (n = 422) were asked to complete a questionnaire and given an ID number, which was used to track market use from 2014 to 2015. Chi square tests were used to examine associations between 2014/2015 market use and reasons for market use, financial support received, and how attendees had learned about the market. Ordinal regression was used to identify household characteristics associated with increased market attendance...
December 14, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/29242840/the-mid-childhood-and-adolescent-antecedents-of-women-s-external-locus-of-control-orientation
#5
Jean Golding, Steven Gregory, Yasmin Iles-Caven, Stephen Nowicki
Background: External locus of control orientation (ELOC) is a powerful predictor of adverse consequences in regard to health, educational attainment, inter-personal relationships and well-being. Although many cross-sectional studies have been carried out, relatively little is known about antecedent factors influencing the development of ELOC. Methods: Over 12,000 pregnant women who enrolled in the Avon Longitudinal Study of Parents and Children (ALSPAC) in south-west England, had completed a brief version of the Adult Nowicki-Strickland Internal-External LOC scale, together with detailed questions concerning their own parents and childhood...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/29242282/patient-reported-comorbidity-and-survival-in-older-adults-with-cancer
#6
Grant R Williams, Allison M Deal, Jennifer L Lund, YunKyung Chang, Hyman B Muss, Mackenzi Pergolotti, Emily J Guerard, Shlomit Strulov Shachar, Yue Wang, Kelly Kenzik, Hanna K Sanoff
BACKGROUND: Our ability to optimize the care of older adults with cancer and comorbid illnesses is insufficient because most clinical trials lack systematic measurement. The primary purpose of this study was to evaluate the association between patient-reported comorbidity and all-cause mortality using various comorbidity scoring algorithms. MATERIALS AND METHODS: The Carolina Senior Registry was linked with the North Carolina Central Cancer Registry to obtain mortality data...
December 14, 2017: Oncologist
https://www.readbyqxmd.com/read/29241996/fracture-related-mortality-in-southern-sweden-a-multiple-cause-of-death-analysis-1998-2014
#7
Aliasghar A Kiadaliri, Björn E Rosengren, Martin Englund
PURPOSE: To assess fracture-related mortality among adults (aged ≥20years) in southern Sweden using multiple causes of death approach. METHODS: All death certificates (n=201 488) in adults recorded in the region of Skåne from 1998 to 2014 were examined. We identified fracture-related deaths and computed mortality rates by sex, age group, and fracture site. Temporal trends were evaluated using joinpoint regression and associated causes were identified by age- and sex-adjusted observed/expected ratios...
December 9, 2017: Injury
https://www.readbyqxmd.com/read/29241886/pcsk9-inhibitors-show-value-for-patients-and-the-us-health-care-system
#8
Wei-Han Cheng, Étienne Gaudette, Dana P Goldman
BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors were approved by the US Food and Drug Administration (FDA) as cholesterol-lowering therapies for patients with familial hypercholesterolemia or atherosclerotic cardiovascular disease. OBJECTIVES: To estimate the long-term health and economic value of PCSK9 inhibitors for Americans (51 years and older). METHODS: We conducted simulations using the Future Elderly Model, an established dynamic microsimulation model to project the lifetime outcomes for the US population aged 51 years and older...
December 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29241884/the-use-of-decomposition-methods-in-real-world-treatment-benefits-evaluation-for-patients-with-type-2-diabetes-initiating-different-injectable-therapies-findings-from-the-initiator-study
#9
Lee Brekke, Erin Buysman, Michael Grabner, Xuehua Ke, Lin Xie, Onur Baser, Wenhui Wei
BACKGROUND: Determining characteristics of patients likely to benefit from a particular treatment could help physicians set personalized targets. OBJECTIVES: To use decomposition methodology on real-world data to identify the relative contributions of treatment effects and patients' baseline characteristics. METHODS: Decomposition analyses were performed on data from the Initiation of New Injectable Treatment Introduced after Antidiabetic Therapy with Oral-only Regimens (INITIATOR) study, a real-world study of patients with type 2 diabetes started on insulin glargine (GLA) or liraglutide (LIRA)...
December 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29241528/the-care-dependency-of-patients-after-laparoscopic-abdominal-surgery-and-associated-factors-in-china
#10
Guangyan Li, Xiangfeng Wang, Lei Liu, Weidong Tong
PURPOSE: The outcome after laparoscopic surgery is dependent on self-care behaviors. Whether or not the patients after laparoscopic abdominal surgery in China are care-dependent is still unclear. Thus, the studies try to analyze influence factors of care dependence on patients with laparoscopic abdominal surgery, to provide reference for personalized care for the patient. METHODS: In our study, two hundreds and forty-two cases were selected and investigated by using the exercise of self-care agency scale and care dependency scale...
December 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/29241502/recruitment-and-retention-of-a-challenging-population-lessons-learned-and-design-implications
#11
Denise Soltow Hershey, Sarah L Hession
PURPOSE: The purpose of this article is share the lessons learned from recruiting and retaining adults with type 2 diabetes and solid tumor cancer into a longitudinal study exploring the relationship among chemotherapy, glycemic control, and symptoms. DESIGN/METHODS: Twelve-week longitudinal study, recruited thirty-four adults 21years or older with pre-existing type 2 diabetes and a solid tumor cancer, from three community based cancer centers who were eligible to receive outpatient chemotherapy...
December 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/29240950/what-did-you-do-today-variability-in-daily-activities-is-related-to-variability-in-daily-cognitive-performance
#12
Allison A M Bielak, Jacqueline Mogle, Martin J Sliwinski
Objectives: Are the activities we do each day related to fluctuations in our daily cognitive performance? Positive longitudinal associations between cognitive, physical, and social activities and cognitive ability in adulthood are well established. However little is known about how this relationship may operate at the daily level. Methods: Community-dwelling participants 60-90 years of age (M = 69.41; n = 146) reported their activity participation and completed cognitive tests online for 7 consecutive days...
December 12, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29240910/genetic-predisposition-to-obesity-and-medicare-expenditures
#13
George L Wehby, Benjamin W Domingue, Fred Ullrich, Fredric D Wolinsky
Background: The relationship between obesity and health expenditures is not well understood. We examined the relationship between genetic predisposition to obesity measured by a polygenic risk score for body mass index (BMI) and Medicare expenditures. Methods: Biennial interview data from the Health and Retirement Survey for a nationally representative sample of older adults enrolled in fee-for-service Medicare were obtained from 1991 through 2010 and linked to Medicare claims for the same period and to Genome-Wide Association Study (GWAS) data...
December 12, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29240531/enhancing-dignity-for-older-inpatients-the-photograph-next-to-the-bed-study
#14
Ruth E Hubbard, Melissa Bak, Jacqueline Watts, David Shum, Angelica Lynch, Nancye M Peel
OBJECTIVES: Older inpatients compromised by illness and cognitive decline may be stripped of physical and cultural identifiers, making them vulnerable to erosion of dignity. This study explored the experiences of patients, carers and clinical staff in response to a simple intervention that could enhance the dignity of care for older inpatients. METHODS: All patients in a rehabilitation ward were encouraged to have a photograph of themselves next to their bed. Of those who participated, focus groups were recruited for patients, family members and staff to explore their reflections...
November 16, 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/29239799/occupational-determinants-of-successful-aging-in-older-physicians
#15
Chanaka Wijeratne, Carmelle Peisah, Joanne Earl, Georgina Luscombe
OBJECTIVES: Demographic, physical and psychological associations of successful aging (SA) have been evaluated, but occupational factors have not. Nor has SA been evaluated in a specific occupational group. The aims of this study were to examine the occupational associations of SA in older physicians, and to explore the concept of occupational SA. METHODS: Physicians aged 55+ years completed self-ratings of occupational and personal SA on a 10-point visual analogue scale (VAS; 1 being "least successful" and 10 "most successful")...
November 24, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29239637/discrete-emotion-regulation-strategy-repertoires-and-parasympathetic-physiology-characterize-psychopathology-symptoms-in-childhood
#16
Laura E Quiñones-Camacho, Elizabeth L Davis
Certain psychopathologies are often linked to dysregulation of specific emotions (e.g., anxiety is associated with dysregulation of fear), but few studies have examined how regulatory repertoires for specific emotions (e.g., the strategies a person uses to regulate fear) relate to psychopathology, and fewer still have examined this in childhood. A total of 106 7- to 11-year-olds (M = 9.37 years; SD = 1.30; 44% girls) participated in a multimethod investigation of emotion regulation and psychopathology. Parents reported on family characteristics and children's symptoms...
December 14, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/29239051/coronary-and-carotid-atherosclerosis-in-asymptomatic-male-marathon-runners
#17
Christof Burgstahler, Hans Cipowicz, Christoph Thomas, Christoph Schabel, Stefanie Mangold, Dominik Ketelsen, Claus D Claussen, Andreas M Niess, Ilias Tsiflikas
The aim of the study was to evaluate the diagnostic accuracy of carotid ultrasound (CU) to predict coronary atherosclerosis in asymptomatic male marathon runners. A total of 49 male marathon runners older than 45 years(mean age 53.3±7.2 years, range 45-74 years) received CU and cardiac CT angiography(CTA) including calcium scoring(CS). Results of CU and CTA were classified binary: 1. Absence of atherosclerosis and 2. presence of atherosclerosis. The extend of atherosclerosis was not primary end-point of the study...
December 14, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29238968/immigrants-coping-with-transnational-deaths-and-bereavement-the-influence-of-migratory-loss-and-anticipatory-grief
#18
Olena Nesteruk
This study examines immigrants' experiences of bereavement and coping with the deaths of family members in a transnational context. Data were collected through in-depth personal interviews with middle-aged and older immigrants from different countries of origin, who have been living in the United States for a majority of their adult lives. Thematic analysis of participants' narratives showed that immigrants' geographic distance from family complicated caregiving circumstances and rituals surrounding burial, and impacted the grieving process...
December 14, 2017: Family Process
https://www.readbyqxmd.com/read/29238963/life-expectancy-after-the-first-suicide-attempt
#19
J Jokinen, M Talbäck, M Feychting, A Ahlbom, R Ljung
OBJECTIVE: To assess excess mortality among suicide attempters compared to the general population. METHOD: Remaining life expectancy was calculated for a nationwide cohort of all 187 894 persons 18 years or older hospitalised for the first time attempted suicide in Sweden in 1971-2010. RESULTS: Life expectancy was shortened throughout the lifespan for both men and women debuting with suicide attempt. The reduction in life expectancy for men debuting with a suicide attempt at 20 years of age was 18 years while the reduction for men debuting at 50 years of age was 10 years...
December 14, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29237477/the-impact-of-glaucoma-on-quality-of-life-in-ethiopia-a-case-control-study
#20
Fisseha A Ayele, Banchamelak Zeraye, Yared Assefa, Kbrom Legesse, Telake Azale, Matthew J Burton
BACKGROUND: Glaucoma is a chronic disease characterized by irreversible optic nerve damage and visual field loss that leads to visual impairment and blindness; ultimately limiting personal independence and compromising overall quality of life of affected individuals. There is paucity of information on how glaucoma affects the quality of life of patients in low and middle-income countries where resources for both diagnosis and treatment of such conditions are limited. In this study we investigate the impact of glaucoma on quality of life in Ethiopian patients...
December 13, 2017: BMC Ophthalmology
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