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https://www.readbyqxmd.com/read/29679534/determinants-of-reverse-remodeling-of-the-left-atrium-following-transaortic-myectomy
#1
Anita Nguyen, Hartzell V Schaff, Rick A Nishimura, Joseph A Dearani, Jeffrey B Geske, Brian D Lahr, Steve R Ommen
BACKGROUND: In patients with hypertrophic cardiomyopathy (HCM), enlargement of the left atrium (LA) is associated with increased morbidity and mortality due to risk of atrial fibrillation (AF), stroke, and heart failure. In this study, we investigated whether LA reverse remodeling occurs following septal myectomy. METHODS: Between March 2007 and July 2015, 656 patients underwent myectomy at our institution and had pre- and postoperative transthoracic echocardiographic (TTE) recording of LA volume index (LAVI)...
April 18, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29667903/posterior-mitral-leaflet-plication-for-hypertrophic-obstructive-cardiomyopathy
#2
Praveen Kerala Varma, Neethu Krishna, Hisham Ahamed, Sujatha Madassery
Anomalies of the mitral valve apparatus in hypertrophic cardiomyopathy are an important cause of systolic anterior motion. Patients with significant residual obstruction due to systolic anterior motion after myectomy and anterior mitral leaflet plication may end up having mitral valve replacement. We describe the case of a 52-year-old man who underwent posterior mitral leaflet plication to correct residual systolic anterior motion after anterior mitral leaflet plication.
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29655822/clinical-spectrum-and-management-of-heart-failure-in-hypertrophic-cardiomyopathy
#3
REVIEW
Barry J Maron, Ethan J Rowin, James E Udelson, Martin S Maron
Heart failure (HF), characterized by excessive exertional dyspnea, is a common complication within the broad clinical spectrum of hypertrophic cardiomyopathy (HCM). HF has become an increasingly prominent management issue with the reduction in sudden deaths due to use of implantable defibrillators in this disease. Exertional dyspnea ranges in severity from mild to severe (New York Heart Association functional classes II to IV) and not uncommonly becomes refractory to medical management, leading to progressive disability, but largely in the absence of pulmonary congestion and volume overload requiring hospitalization...
April 5, 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/29628474/preoperative-simulation-using-ct-virtual-endoscopy-for-minimally-invasive-surgery-of-hypertrophic-obstructive-cardiomyopathy
#4
Toshinori Totsugawa, Masatoshi Tsunoda, Nobuyuki Kagiyama, Yuki Otsuki, Hidenori Yoshitaka, Taichi Sakaguchi
Transaortic septal myectomy is a procedure that involves a learning curve for surgeons because the bulging interventricular septum usually interferes with the visualization of the deep parts of the left ventricular chamber. In this case report, we demonstrate computed tomography virtual endoscopy for preoperative simulation, which enabled us to clearly image the relationship among the bulging septum, the expected myectomy area, and the structures deep in the left ventricle, such as the papillary muscle and abnormal muscular bundles, which are hidden by the hypertrophic septum, thus preventing visualization...
April 6, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29607159/application-of-3d-printing-in-the-surgical-planning-of-hypertrophic-obstructive-cardiomyopathy-and-physician-patient-communication-a-preliminary-study
#5
Hong-Chang Guo, Yang Wang, Jiang Dai, Chang-Wei Ren, Jin-Hua Li, Yong-Qiang Lai
Background: The aim of this study was to evaluate the effect of 3-dimensional (3D) printing in treatment of hypertrophic obstructive cardiomyopathy (HOCM) and its roles in doctor-patient communication. Methods: 3D-printed models were constructed preoperatively and postoperatively in seven HOCM patients received surgical treatment. Based on multi-slice computed tomography (CT) images, regions of disorder were segmented using the Mimics 19.0 software (Materialise, Leuven, Belgium)...
February 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29602755/pathoanatomic-findings-and-treatment-during-hypertrophic-obstructive-cardiomyopathy-surgery-the-role-of-mitral-valve
#6
Giuseppe M Raffa, Giuseppe Romano, Marco Turrisi, Marco Morsolini, Giovanni Gentile, Sergio Sciacca, Alessandro Armaro, Vincenzo Stringi, Gabriella Mattiucci, Serena Magro, Fabiola Cosentino, Francesco Clemenza, Michele Pilato
BACKGROUND: To assess the role of the mitral valve apparatus (leaflets, chordae and papillary muscles, PM) in left ventricle outflow tract (LVOT) obstruction, and results of the surgical treatment for hypertrophic obstructive cardiomyopathy (HOCM). METHODS: Twenty-eight consecutive patients (58±11years, 53% female) undergoing HOCM surgery from 2007 to 2016 at our institute were retrospectively reviewed. Endpoints included the involvement of the mitral valve in LVOT obstruction, mortality, and changes in clinical and echocardiographic characteristics after HOCM surgery...
February 14, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29571985/serotonin-syndrome-following-septal-myectomy-in-association-with-fentanyl-and-methylene-blue-a-case-report
#7
Lindsay Haacker, MaryJo Maliekel, Christina E Hantsch Bardsley, Ryan Bergren, Edwin Meresh, Angelos Halaris
No abstract text is available yet for this article.
February 13, 2018: Psychosomatics
https://www.readbyqxmd.com/read/29569368/optimal-reconstruction-of-left-ventricular-outflow-tract-obstruction-before-surgical-myectomy-in-a-case-with-hypertrophic-obstructive-cardiomyopathy
#8
Hiroyuki Toh, Shumpei Mori, Shinsuke Shimoyama, Yu Izawa, Shun Yokota, Yuto Shinkura, Ryo Takeshige, Akira Nagasawa, Fumitaka Soga, Hidekazu Tanaka, Toshiro Shinke, Koki Yokawa, Takashi Matsueda, Yutaka Okita, Ken-Ichi Hirata
We present optimally reconstructed three-dimensional computed tomography images of left ventricular outflow obstruction, comprehensive left ventriculography, and comparable intraoperative transesophageal echocardiography, as well as serial operative pictures, to facilitate the understanding of live-heart anatomy of hypertrophic obstructive cardiomyopathy. As shown in this case, detailed morphological analysis around the left ventricular outflow tract using preoperative computed tomography would be feasible and useful...
March 22, 2018: Echocardiography
https://www.readbyqxmd.com/read/29549506/minimally-invasive-trans-mitral-septal-myectomy-for-diffuse-type-hypertrophic-obstructive-cardiomyopathy
#9
Taichi Sakaguchi, Toshinori Totsugawa, Kentaro Tamura, Arudo Hiraoka, Genta Chikazawa, Hidenori Yoshitaka
OBJECTIVE: Despite excellent long-term results reported for a trans-aortic septal myectomy for hypertrophic obstructive cardiomyopathy (HOCM), surgery for patients with diffuse hypertrophy is very challenging. In addition, a left ventricular outflow obstruction is often aggravated by an abnormal mitral valve and subvalvular apparatus. METHODS: We performed video-assisted minimally invasive trans-mitral septal myectomy procedures in 3 patients with diffuse-type HOCM, who were highly symptomatic despite maximal medical therapy...
March 16, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29548833/clinical-and-ocular-motor-complications-of-extraocular-muscle-extirpation-for-infantile-nystagmus-syndrome
#10
Louis F Dell'Osso, Richard W Hertle, Jonathan B Jacobs
PURPOSE: To describe the effects of extraocular muscle extirpation performed after previous eye muscle surgery in a 20-year-old woman with infantile nystagmus syndrome (INS) for whom we have 19 years of follow-up data. METHODS: Clinical examinations were performed. Eye movement data analysis was carried out using the eXpanded Nystagmus Acuity Function (NAFX) and longest foveation domain (LFD). RESULTS: The patient re-presented to the authors at age 20, 2 years after bilateral anterior myectomy of the horizontal rectus muscles, bilateral anterior nasal transposition of the inferior oblique muscle, and bilateral superior oblique recessions...
March 13, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29524602/surgical-approaches-to-hypertrophic-obstructive-cardiomyopathy
#11
Zachary Solomon, Catalina Breton, Ethan J Rowin, Barry J Maron, Martin S Maron, Frederick Y Chen, Hassan Rastegar
Left ventricular outflow tract obstruction secondary to hypertrophic obstructive cardiomyopathy remains a challenging entity facing clinicians. Despite the success of invasive therapies, some clinicians remain hesitant due to early results with unacceptable morbidity and mortality rates. However, current literature strongly suggests improved short and long-term outcomes with extended septal myectomy and alcohol septal ablation compared to patients not undergoing such interventions. This review evaluates hypertrophic obstructive cardiomyopathy treatment with a focus on short and long-term outcomes, perioperative complications, and major tenets of surgical intervention...
March 7, 2018: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29502589/intraoperative-two-and-three-dimensional-transesophageal-echocardiography-in-combined-myectomy-mitral-operations-for-hypertrophic-cardiomyopathy
#12
REVIEW
Robert G Nampiaparampil, Daniel G Swistel, Michael Schlame, Muhamed Saric, Mark V Sherrid
Transesophageal echocardiography is essential in guiding the surgical approach for patients with obstructive hypertrophic cardiomyopathy. Septal hypertrophy, elongated mitral valve leaflets, and abnormalities of the subvalvular apparatus are prominent features, all of which may contribute to left ventricular outflow tract obstruction. Surgery aims to alleviate the obstruction via an extended myectomy, often with an intervention on the mitral valve and subvalvular apparatus. The goal of intraoperative echocardiography is to assess the anatomic pathology and pathophysiology in order to achieve a safe intraoperative course and a successful repair...
March 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29496436/myectomy-and-la-to-lv-conduit-for-severe-calcific-mitral-stenosis-and-hypertrophic-cardiomyopathy
#13
Zahara Meghji, Anita Nguyen, Jeffrey B Geske, Hartzell V Schaff
Severe calcific mitral valve stenosis can rarely occur concomitantly with obstructive hypertrophic cardiomyopathy. In these patients, surgical decalcification of the stenotic mitral valve followed by mitral valve replacement carries significant operative risk and may result in paravalvular leakage, atrioventricular groove disruption, and excessive bleeding. We report the first 2 cases of obstructive hypertrophic cardiomyopathy with severe calcific mitral valve stenosis successfully treated with concomitant transaortic septal myectomy and bypass of the stenotic mitral valve using a valved left atrium to left ventricular conduit...
February 26, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29490994/long-term-outcomes-of-hypertrophic-cardiomyopathy-diagnosed-during-childhood-results-from-a-national-population-based-study
#14
Peta M A Alexander, Alan W Nugent, Piers E F Daubeney, Katherine J Lee, Lynn A Sleeper, Tibor Schuster, Christian Turner, Andrew M Davis, Chris Semsarian, Steven D Colan, Terry Robertson, James Ramsay, Robert Justo, Gary F Sholler, Ingrid King, Robert G Weintraub
Background -Late survival and symptomatic status of children with hypertrophic cardiomyopathy (HCM) have not been well defined. We examined long-term outcomes for pediatric HCM. Methods -The National Australian Childhood Cardiomyopathy Study is a longitudinal population-based cohort study of children (0-10 years) diagnosed with cardiomyopathy between 1987 and 1996. The primary study end-point was time to death or cardiac transplantation. Results -There were 80 patients with HCM with median age at diagnosis of 0...
February 28, 2018: Circulation
https://www.readbyqxmd.com/read/29483385/comparison-of-clinical-effects-between-percutaneous-transluminal-septal-myocardial-ablation-and-modified-morrow-septal-myectomy-on-patients-with-hypertrophic-cardiomyopathy
#15
Hong-Chang Guo, Jin-Hua Li, Teng-Yong Jiang, Chang-Wei Ren, Jiang Dai, Yu-Jie Zhou, Yong-Qiang Lai
Background: Percutaneous transluminal septal myocardial ablation (PTSMA) and modified Morrow septal myectomy (MMSM) are two invasive strategies used to relieve obstruction in patients with hypertrophic cardiomyopathy (HCM). This study aimed to determine the clinical outcome of these two strategies. Methods: From January 2011 to January 2015, 226 patients with HCM were treated, 68 by PTSMA and 158 by MMSM. Both ultrasonic cardiograms and heart functional class were recorded before, after operations and in the follow-up...
March 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29453593/risk-marker-profiles-in-patients-treated-with-percutaneous-septal-ablation-for-symptomatic-hypertrophic-obstructive-cardiomyopathy
#16
Amelie Burghardt, Frank van Buuren, Zisis Dimitriadis, Tim Grübbel, Hubert Seggewiss, Smita Scholtz, Dieter Horstkotte, Lothar Faber
BACKGROUND AND STUDY OBJECTIVE: Different studies have shown a good long-term survival with improvement of symptoms and hemodynamics after percutaneous septal ablation (PTSMA), similar to myectomy considered to be the therapeutic "gold standard" for symptomatic hypertrophic obstructive cardiomyopathy (HOCM). Furthermore, desobliteration of left ventricular (LV) outflow may modify features of the disease considered to be risk-relevant, such as magnitude of LV hypertrophy, outflow gradient, and left atrial (LA) size...
February 16, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29453001/transmitral-septal-myectomy-for-hypertrophic-obstructive-cardiomyopathy
#17
Brody Wehman, Mehrdad Ghoreishi, Nathaniel Foster, Libin Wang, Michael N D'Ambra, Nathan Maassel, Sam Maghami, Rachael Quinn, Murtaza Dawood, Stacy Fisher, James S Gammie
BACKGROUND: Intrinsic abnormalities of the mitral valve are common in patients with hypertrophic cardiomyopathy and may need to be addressed at operation. METHODS: Consecutive patients undergoing transmitral septal myectomy were retrospectively reviewed. The ventricular septum was exposed through a left atriotomy, and the anterior leaflet of the mitral valve was detached from its annulus. An extended myectomy was performed to the base of the papillary muscles. After myectomy, the anterior leaflet was reattached and concomitant mitral valve repair or replacement was performed...
February 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29450766/septal-myectomy-for-hypertrophic-cardiomyopathy-important-surgical-knowledge-and-technical-tips-in-the-era-of-increasing-alcohol-septal-ablation
#18
REVIEW
Yuting P Chiang, Yuichi J Shimada, Jonathan Ginns, Shepard D Weiner, Hiroo Takayama
Hypertrophic cardiomyopathy (HCM) is the most commonly inherited cardiac disease-recent studies suggest a prevalence as high as 1 in 200. For symptomatic patients with obstructive HCM who are refractory to medical therapy, septal reduction is indicated. Septal myectomy (SM) is considered the gold standard septal reduction technique. However, due to a shortage of surgeons who are experienced in this technique, alcohol septal ablation (ASA) has overtaken SM as the most commonly performed procedure for obstructive HCM...
February 15, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29444294/prognosis-of-adult-obstructive-hypertrophic-cardiomyopathy-patients-with-different-morphological-types-after-surgical-myectomy
#19
Bing Tang, Yunhu Song, Hao Cui, Keshan Ji, Qinjun Yu, Changsheng Zhu, Shihua Zhao, Shuiyun Wang
OBJECTIVES: This study aims to assess the impact of morphological type on the prognosis of obstructive hypertrophic cardiomyopathy patients who underwent myectomy. METHODS: We recruited 469 obstructive hypertrophic cardiomyopathy patients refractory to medicinal treatment who have undergone surgical myectomy at a nationwide referral centre. All patients were divided into 3 groups based on the morphological classification of left ventricular hypertrophy and were followed up by telephone every year...
February 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29438530/hypertrophic-obstructive-cardiomyopathy-what-when-why-for-whom
#20
Carlos A Mestres, Thomas Bartel, Antonio Sorgente, Silvana Müller, Christiane Gruner, Joseph Dearani, Eduard Quintana
Hypertrophic cardiomyopathy is the most common genetic cardiovascular disorder and is associated with symptoms of heart failure and increased risk of sudden cardiac death. The most common condition is obstruction of the left ventricular outflow tract. Surgical septal myectomy and alcohol septal ablation are the 2 accepted modes of septal reduction therapy and are indicated when there are advanced symptoms and a peak left ventricular outflow gradient ≥50 mmHg. Advantages of alcohol septal ablation are limited groin approach, reduction of obstruction of the left ventricular outflow tract and functional improvement, but there are higher chances for intracardiac device implantation and residual obstruction...
February 9, 2018: European Journal of Cardio-thoracic Surgery
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