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https://www.readbyqxmd.com/read/28635643/a-multi-wavelength-opto-electronic-patch-sensor-to-effectively-detect-physiological-changes-against-human-skin-types
#1
Liangwen Yan, Sijung Hu, Abdullah Alzahrani, Samah Alharbi, Panagiotis Blanos
Different skin pigments among various ethnic group people have an impact on spectrometric illumination on skin surface. To effectively capture photoplethysmographic (PPG) signals, a multi-wavelength opto-electronic patch sensor (OEPS) together with a schematic architecture of electronics were developed to overcome the drawback of present PPG sensor. To perform a better in vivo physiological measurement against skin pigments, optimal illuminations in OEPS, whose wavelength is compatible with a specific skin type, were optimized to capture a reliable physiological sign of heart rate (HR)...
June 21, 2017: Biosensors
https://www.readbyqxmd.com/read/28634442/mild-traumatic-brain-injury-evokes-pyramidal-neuron-axon-initial-segment-plasticity-and-diffuse-presynaptic-inhibitory-terminal-loss
#2
Michal Vascak, Jianli Sun, Matthew Baer, Kimberle M Jacobs, John T Povlishock
The axon initial segment (AIS) is the site of action potential (AP) initiation, thus a crucial regulator of neuronal activity. In excitatory pyramidal neurons, the high density of voltage-gated sodium channels (NaV1.6) at the distal AIS regulates AP initiation. A surrogate AIS marker, ankyrin-G (ankG) is a structural protein regulating neuronal functional via clustering voltage-gated ion channels. In neuronal circuits, changes in presynaptic input can alter postsynaptic output via AIS structural-functional plasticity...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28634237/the-pseudomonas-aeruginosa-psl-polysaccharide-is-a-social-but-noncheatable-trait-in-biofilms
#3
Yasuhiko Irie, Aled E L Roberts, Kasper N Kragh, Vernita D Gordon, Jaime Hutchison, Rosalind J Allen, Gavin Melaugh, Thomas Bjarnsholt, Stuart A West, Stephen P Diggle
Extracellular polysaccharides are compounds secreted by microorganisms into the surrounding environment, and they are important for surface attachment and maintaining structural integrity within biofilms. The social nature of many extracellular polysaccharides remains unclear, and it has been suggested that they could function as either cooperative public goods or as traits that provide a competitive advantage. Here, we empirically tested the cooperative nature of the PSL polysaccharide, which is crucial for the formation of biofilms in Pseudomonas aeruginosa We show that (i) PSL is not metabolically costly to produce; (ii) PSL provides population-level benefits in biofilms, for both growth and antibiotic tolerance; (iii) the benefits of PSL production are social and are shared with other cells; (iv) the benefits of PSL production appear to be preferentially directed toward cells which produce PSL; (v) cells which do not produce PSL are unable to successfully exploit cells which produce PSL...
June 20, 2017: MBio
https://www.readbyqxmd.com/read/28627111/european-surveillance-system-on-contact-allergies-essca-results-with-the-european-baseline-series-2013-14
#4
W Uter, J C Amario-Hita, A Balato, B Ballmer-Weber, A Bauer, A Belloni Fortina, A Bircher, M M U Chowdhury, S M Cooper, A Dugonik, R Gallo, A Giménez-Arnau, J D Johansen, S M John, M Kieć-Świerczyńska, T Kmecl, B Kręcisz, F Larese Filon, V Mahler, M Pesonen, T Rustemeyer, A Sadowska-Przytocka, J Sánchez-Perez, S Schliemann, M L Schuttelaar, D Simon, R Spiewak, S Valiukeviciene, E Weisshaar, I R White, S M Wilkinson
BACKGROUND: Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, a consequence of introduction of new substances, new products or formulations, and regulatory intervention, the spectrum of contact sensitisation changes. OBJECTIVE: To evaluate the current spectrum of contact allergy to allergens present in the European baseline series (EBS) across Europe. METHODS: Retrospective analysis of data collected by the European Surveillance System on Contact Allergies (ESSCA, www...
June 19, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28621617/intrathoracic-meningocele-associated-with-neurofibromatosis-type-1-and-a-novel-technique-for-surgical-repair-case-report
#5
Paramita Das, Tarini Goyal, Matthew A Hunt
Neurofibromatosis Type 1 (NF1) is a neurocutaneous disorder that can have associated spinal abnormalities related to both bone and dural dysplasia. Thoracic meningoceles are one spine anomaly associated with NF1, although they are a fairly uncommon pathology. Surgical techniques to treat these meningoceles, usually undertaken only when the patient is symptomatic, are targeted at decreasing the size of the protrusion and improving lung capacity. Surgical interventions discussed in the literature include shunting the pseudomeningocele, primary repair with laminectomy, thoracoscopic plication, and reinforcement of the closure with cement, muscle, or fascia...
June 16, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28620577/population-structure-of-the-soft-tick-ornithodoros-maritimus-and-its-associated-infectious-agents-within-a-colony-of-its-seabird-host-larus-michahellis
#6
Marlene Dupraz, Céline Toty, Elodie Devillers, Thomas Blanchon, Eric Elguero, Marion Vittecoq, Sara Moutailler, Karen D McCoy
The epidemiology of vector-borne zoonoses depends on the movement of both hosts and vectors, which can differ greatly in intensity across spatial scales. Because of their life history traits and small size, vector dispersal may be frequent, but limited in distance. However, little information is available on vector movement patterns at local spatial scales, and particularly for ticks, transmitting the greatest diversity of recognized infectious agents. To test the degree to which ticks can disperse and disseminate pathogens at local scales, we investigated the temporal dynamics and population structure of the soft tick Ornithodoros maritimus within a colony of its seabird host, the Yellow-legged gull Larus michahellis...
August 2017: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/28620305/comparative-effects-of-chloride-channel-inhibitors-on-lrrc8-vrac-mediated-chloride-conductance
#7
Jonas Friard, Michel Tauc, Marc Cougnon, Vincent Compan, Christophe Duranton, Isabelle Rubera
Chloride channels play an essential role in a variety of physiological functions and in human diseases. Historically, the field of chloride channels has long been neglected owing to the lack of powerful selective pharmacological agents that are needed to overcome the technical challenge of characterizing the molecular identities of these channels. Recently, members of the LRRC8 family have been shown to be essential for generating the volume-regulated anion channel (VRAC) current, a chloride conductance that governs the regulatory volume decrease (RVD) process...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28620124/a-high-throughput-field-based-phenotyping-technology-for-tall-biomass-crops
#8
Maria G Salas Fernandez, Yin Bao, Lie Tang, Patrick S Schnable
Recent advances in "omics" technologies have not been accompanied by equally efficient, cost-effective and accurate phenotyping methods required to dissect the genetic architecture of complex traits. Even though high-throughput phenotyping platforms have been developed for controlled environments, field-based aerial and ground technologies have only been designed and deployed for short stature crops. Therefore, we developed and tested Phenobot 1.0, an auto-steered and self-propelled field-based high-throughput phenotyping platform for tall dense canopy crops, such as sorghum (Sorghum bicolor L...
June 15, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28618737/effects-of-artcure-diffusional-patch-application-on-pain-and-functional-status-in-lumbar-disc-herniation-patients-a-prospective-randomized-controlled-study
#9
Mahmut Uğurlu, Mehmet Atıf Erol Aksekili, Berat Meryem Alkan, Halil Kara, Ceyhun Çağlar
BACKGROUND/AIM: The aim of this study was to assess the efficacy of the Artcure Diffusional Patch, which contains a mixture of 6 herbal oils (oleum thymi, oleum limonis, oleum nigra, oleum rosmarini, oleum chamomilla, oleum lauriexpressum) and has a hypoosmolar lipid structure, in the conservative treatment of lumbar disc herniation patients and to show the advantages and/or possibility of using this as an alternative method to surgery. MATERIALS AND METHODS: Of the 120 patients enrolled, 79 clinically diagnosed patients were included in the study...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28618637/actin-growth-profile-in-clathrin-mediated-endocytosis
#10
D J Tweten, P V Bayly, A E Carlsson
Clathrin-mediated endocytosis in yeast is driven by a protein patch containing close to 100 different types of proteins. Among the proteins are 5000-10000 copies of polymerized actin, and successful endocytosis requires growth of the actin network. Since it is not known exactly how actin network growth drives endocytosis, we calculate the spatial distribution of actin growth required to generate the force that drives the process. First, we establish the force distribution that must be supplied by actin growth, by combining membrane-bending profiles obtained via electron microscopy with established theories of membrane mechanics...
May 2017: Physical Review. E
https://www.readbyqxmd.com/read/28617697/evaluation-of-the-temple-touch-pro-a-novel-noninvasive-core-temperature-monitoring-system
#11
Shmuel Evron, Avi Weissman, Vadim Toivis, Dana Baron Shahaf, Jing You, Daniel I Sessler, Tiberiu Ezri
BACKGROUND: The Temple Touch Pro (TTP) is a novel system that estimates core temperature from skin over the temporal artery. We tested the hypothesis that this noninvasive system estimates core temperature to an accuracy within 0.5°C. METHODS: Core temperature was continuously monitored in 50 adult and pediatric surgical patients by positioning the sensor patch of a TTP over one temporal artery. The sensor consists of a thermistor array near the skin surface, another set of thermistors above an insulator, and a second insulator between the upper unit and the environment...
July 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28617679/bendamustine-induced-acute-generalized-exanthematous-pustulosis-confirmed-by-patch-testing
#12
Ira Daniel Harber, Kristen V Adams, Kathleen Casamiquela, Stephen Helms, Brandon T Benson, Vince Herrin
No abstract text is available yet for this article.
June 14, 2017: Dermatitis
https://www.readbyqxmd.com/read/28615326/prenatal-nicotinic-exposure-prolongs-superior-laryngeal-c-fiber-mediated-apnea-and-bradycardia-through-enhancing-neuronal-trpv1-expression-and-excitation
#13
Xiuping Gao, Lei Zhao, Jianguo Zhuang, Na Zang, Fadi Xu
Maternal cigarette smoke, including prenatal nicotinic exposure (PNE), is responsible for sudden infant death syndrome (SIDS). The fatal events of SIDS are characterized by severe bradycardia and life-threatening apneas. Although activation of transient receptor potential vanilloid 1 (TRPV1) of superior laryngeal C-fibers (SLCFs) could induce bradycardia and apnea and has been implicated in SIDS pathogenesis, how PNE affects the SLCF-mediated cardiorespiratory responses remains unexplored. Here, we tested the hypothesis that PNE would aggravate the SLCF-mediated apnea and bradycardia via up-regulating TRPV1 expression and excitation of laryngeal C-neurons in the nodose/jugular (N/J) ganglia...
June 14, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28614106/positive-patch-test-reactions-to-essential-oils-in-consecutive-patients-results-from-north-america-and-central-europe
#14
Erin M Warshaw, Kathryn A Zug, Donald V Belsito, Joseph F Fowler, Joel G DeKoven, Denis Sasseville, Howard I Maibach, C G Toby Mathias, Vincent A DeLeo, James S Taylor, Anthony F Fransway, James G Marks, Melanie D Pratt, Matthew J Zirwas, Johannes Geier, Wolfgang Uter
BACKGROUND: Synthetic fragrances and natural essential oils (EOs) are used in perfumery and found in various cosmetics. Essential oils are also increasingly used to promote wellness. In previous studies, the sensitization potential of some EOs has been identified; however, the current prevalence of sensitivity is largely unknown. OBJECTIVES: The aim of this study was to determine frequency of positive patch-test reactions to EOs tested in the baseline series, along with 3 fragrance markers (FMs) (fragrance mix I, fragrance mix II, and Myroxylon pereirae), in consecutive patients in the US/Canadian North American Contact Dermatitis Group (NACDG) (2009-2014) and the central European, trinational Information Network of Departments of Dermatology (IVDK) (2010-2014)...
June 13, 2017: Dermatitis
https://www.readbyqxmd.com/read/28611994/common-allergens-identified-based-on-patch-test-results-in-patients-with-suspected-contact-dermatitis-of-the-scalp
#15
Nouf M Aleid, Raymond Fertig, Austin Maddy, Antonella Tosti
BACKGROUND: Contact dermatitis of the scalp is common and might be caused by many chemicals including metals, ingredients of shampoos and conditioners, dyes, or other hair treatments. Eliciting a careful history and patch tests are necessary to identify the responsible allergen and prevent relapses. OBJECTIVES: To identify allergens that may cause contact dermatitis of the scalp by reviewing patch test results. METHODS: We reviewed the records of 1,015 patients referred for patch testing at the Dermatology Department of the University of Miami...
March 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28611806/opportunities-and-constraints-in-characterizing-landscape-distribution-of-an-invasive-grass-from-very-high-resolution-multi-spectral-imagery
#16
Iryna Dronova, Erica N Spotswood, Katharine N Suding
Understanding spatial distributions of invasive plant species at early infestation stages is critical for assessing the dynamics and underlying factors of invasions. Recent progress in very high resolution remote sensing is facilitating this task by providing high spatial detail over whole-site extents that are prohibitive to comprehensive ground surveys. This study assessed the opportunities and constraints to characterize landscape distribution of the invasive grass medusahead (Elymus caput-medusae) in a ∼36...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28610919/neural-differentiation-of-human-embryonic-stem-cells-induced-by-the-transgene-mediated-overexpression-of-single-transcription-factors
#17
Misako Matsushita, Yuhki Nakatake, Itaru Arai, Keiji Ibata, Kazuhisa Kohda, Sravan K Goparaju, Miyako Murakami, Miki Sakota, Nana Chikazawa-Nohtomi, Shigeru B H Ko, Takanori Kanai, Michisuke Yuzaki, Minoru S H Ko
Pluripotent human embryonic stem cells (hESCs) can differentiate into multiple cell lineages, thus, providing one of the best platforms to study molecular mechanisms during cell differentiation. Recently, we have reported rapid and efficient differentiation of hESCs into functional neurons by introducing a cocktail of synthetic mRNAs encoding five transcription factors (TFs): NEUROG1, NEUROG2, NEUROG3, NEUROD1, and NEUROD2. Here we further tested a possibility that even single transcription factors, when expressed ectopically, can differentiate hESCs into neurons...
June 10, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28610718/echinacea-purpurea-derived-alkylamides-exhibit-potent-anti-inflammatory-effects-and-alleviate-clinical-symptoms-of-atopic-eczema
#18
Attila Oláh, Judit Szabó-Papp, Michael Soeberdt, Ulrich Knie, Stephan Dähnhardt-Pfeiffer, Christoph Abels, Tamás Bíró
BACKGROUND: Atopic eczema (AE) is a chronic inflammatory and pruritic skin disease. There is still an unmet need for topical anti-inflammatory and anti-pruritic substances exhibiting an excellent safety profile. The endocannabinoid system is known to regulate various aspects of cutaneous barrier and immune functions, thus targeting it may be a valid approach for alleviating the symptoms of AE. OBJECTIVE: To assess the putative efficacy of Echinacea purpurea-derived alkylamides (Ec...
May 27, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28607794/a-rare-case-of-vasculitis-patched-necrosis-of-cecum-due-to-beh%C3%A3-et-s-disease
#19
Ehsan Shahverdi, Mehdi Morshedi, Faraneh Oraei-Abbasian, Maryam Allahverdi Khani, Roya Khodayarnejad
Isolated cecal necrosis is a rare form of acute ischemic colitis and a rare cause of surgical abdomen. Behçet's disease is a multisystemic autoimmune condition which can induce vasculitis. This can result in cecal necrosis while disease involves colon vessels. We describe a patient with complicated Behçet's disease and ischemic colitis admitted to our hospital. Patient was a 62-year-old female with more accompanying diseases. Histopathologic findings confirmed the diagnosis of ischemic colitis and regarding patient's vision problem and skin lesions, rheumatologic tests were performed which were positive for HLAB5 and HLAB51 suggestive of Behçet's disease; the patient was improved with surgery...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28607193/hydrogen-embrittlement-the-game-changing-factor-in-the-applicability-of-nickel-alloys-in-oilfield-technology
#20
Helmuth Sarmiento Klapper, Jutta Klöwer, Olesya Gosheva
Precipitation hardenable (PH) nickel (Ni) alloys are often the most reliable engineering materials for demanding oilfield upstream and subsea applications especially in deep sour wells. Despite their superior corrosion resistance and mechanical properties over a broad range of temperatures, the applicability of PH Ni alloys has been questioned due to their susceptibility to hydrogen embrittlement (HE), as confirmed in documented failures of components in upstream applications. While extensive work has been done in recent years to develop testing methodologies for benchmarking PH Ni alloys in terms of their HE susceptibility, limited scientific research has been conducted to achieve improved foundational knowledge about the role of microstructural particularities in these alloys on their mechanical behaviour in environments promoting hydrogen uptake...
July 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
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