keyword
MENU ▼
Read by QxMD icon Read
search

ventilatory muscle

keyword
https://www.readbyqxmd.com/read/29327943/phenotyping-pharyngeal-pathophysiology-using-polysomnography-in-patients-with-obstructive-sleep-apnea
#1
Scott A Sands, Bradley A Edwards, Philip I Terrill, Luigi Taranto-Montemurro, Ali Azarbarzin, Melania Marques, Lauren Hess, David P White, Andrew Wellman
RATIONALE: Therapies for obstructive sleep apnea (OSA) could be administered based on a patient's own phenotypic causes ("traits") if a clinically-applicable approach were available. Here we present a novel approach to quantify two key contributors to OSA-pharyngeal collapsibility and compensatory muscle responsiveness-that is applicable to diagnostic polysomnography. METHODS: Based on physiological definitions, pharyngeal collapsibility determines the ventilation at normal (eupneic) ventilatory drive during sleep, and pharyngeal compensation determines the rise in ventilation accompanying a rising ventilatory drive...
January 12, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29327178/clinical-impact-and-risk-factors-for-skeletal-muscle-loss-after-complete-resection-of-early-non-small-cell-lung-cancer
#2
Shinkichi Takamori, Gouji Toyokawa, Tatsuro Okamoto, Mototsugu Shimokawa, Fumihiko Kinoshita, Yuka Kozuma, Taichi Matsubara, Naoki Haratake, Takaki Akamine, Kazuki Takada, Masakazu Katsura, Fumihiko Hirai, Fumihiro Shoji, Tetsuzo Tagawa, Yoshinao Oda, Hiroshi Honda, Yoshihiko Maehara
BACKGROUND: A relationship between sarcopenia diagnosed by skeletal muscle area (SMA) and poor prognosis in cancer patients has recently been reported. This study aimed to clarify the clinical significance of postoperatively decreased SMA in patients with early non-small cell lung cancer (NSCLC). METHODS: This study selected 101 patients with pathologic stage 1 NSCLC who had undergone pre- and postoperative (~ 1 year) computed tomography scans and lobectomy between 2005 and 2010 at Kyushu University Hospital...
January 11, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29284165/lactate-threshold-as-a-measure-of-aerobic-metabolism-in-resistance-exercise
#3
Raúl Domínguez, José Luis Maté-Muñoz, Noemí Serra-Paya, Manuel Vicente Garnacho-Castaño
In resistance training, load intensity is usually calculated as the percentage of a maximum repetition (1RM) or maximum number of possible repetitions (% of 1RM). Some studies have proposed a lactate threshold (LT) intensity as an optimal approach for concurrent training of cardiorespiratory endurance and muscle strength, as well as an alternative in resistance training. The objective of the present study was to analyze the results obtained in research evaluating the use of LT in resistance training. A keyword and search tree strategy identified 14 relevant articles in the Dialnet, Elsevier, Medline, Pubmed, Scopus and Web of Science databases...
December 28, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29240004/synchronizing-gait-with-cardiac-cycle-phase-alters-heart-rate-response-during-running
#4
Keren Constantini, Abigail S L Stickford, Jeffery L Bleich, Paul D Mannheimer, Benjamin D Levine, Robert F Chapman
Timing foot strike to occur in synchrony with cardiac diastole may reduce left ventricular afterload and promote coronary and skeletal muscle perfusion. PURPOSE: To assess heart rate (HR) and metabolic responses to running when foot strikes are timed to occur exclusively during 1) the systolic phase of the cardiac cycle, or 2) the diastolic phase. METHODS: Ten elite male distance runners performed a testing session on a treadmill at 4.72 m[BULLET OPERATOR]s while matching their steps to an auditory tone and wearing a chest strap that transmitted accelerometer and ECG signals...
December 12, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29239779/gender-differences-in-residual-effect-of-prior-drop-jumps-on-oxygen-uptake-during-heavy-cycling-exercise
#5
Neringa Baranauskienė, Sandra Kilikevičienė, Loreta Stasiulė, Genuvaitė Civinskienė, Arvydas Stasiulis
BACKGROUND AND OBJECTIVE: Unaccustomed eccentric or eccentric-concentric exercise leaves us stiff and sore the next day and can cause muscle damage. The data about the residual effect of prior eccentric-concentric exercises on oxygen uptake (VO2) during constant cycling exercise in women or the data about differences of such effect between genders are scarce. Therefore, the aim of this study was to assess differences of the residual effect of PDJ on VO2 during HCE and indirect muscle damage parameters between women and men...
November 1, 2017: Medicina
https://www.readbyqxmd.com/read/29234684/changes-in-the-diaphragm-lipid-content-after-administration-of-streptozotocin-and-high-fat-diet-regime
#6
Bartlomiej Lukaszuk, Agnieszka Miklosz, Malgorzata Zendzian-Piotrowska, Beata Wojcik, Jan Gorski, Adrian Chabowski
The diaphragm is a dome-shaped skeletal muscle indispensable for breathing. Its activity contributes up to 70% of the total ventilatory function at rest. In comparison to other skeletal muscles, it is distinguished by an oxidative phenotype and uninterrupted cyclic contraction pattern. Surprisingly, the research regarding diaphragm diabetic phenotype particularly in the light of lipid-induced insulin resistance is virtually nonexistent. Male Wistar rats were randomly allocated into 3 groups: control, streptozotocin-induced (STZ) type-1 diabetes, and rodents fed with high-fat diet (HFD)...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29227735/effect-of-8-weeks-of-concurrent-plyometric-and-running-training-on-spatiotemporal-and-physiological-variables-of-novice-runners
#7
Josué Gómez-Molina, Ana Ogueta-Alday, Jesus Camara, Christopher Stickley, Juan García-López
Concurrent plyometric and running training has the potential to improve running economy (RE) and performance through increasing muscle strength and power, but the possible effect on spatiotemporal parameters of running has not been studied yet. The aim of this study was to compare the effect of 8 weeks of concurrent plyometric and running training on spatiotemporal parameters and physiological variables of novice runners. Twenty-five male participants were randomly assigned into two training groups; running group (RG) (n = 11) and running + plyometric group (RPG) (n = 14)...
December 11, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/29209502/monitoring-diaphragm-function-in-a-patient-with-myasthenia-gravis-electrical-activity-of-the-diaphragm-vs-maximal-inspiratory-pressure
#8
Yukiko Koyama, Takeshi Yoshida, Akinori Uchiyama, Yuji Fujino
Background: Maximal inspiratory pressure (MIP) is used to assess respiratory muscle strength of patients with myasthenia gravis (MG) requiring ventilatory support. Electrical activity of the diaphragm (E-di) has been used to guide weaning. Case presentation: The MIP and tidal volume/ΔE-di (the patient-to-ventilator breath contribution) were monitored in a 12-year-old girl with MG requiring ventilator support. The same ventilatory settings were maintained until extubation...
2017: Journal of Intensive Care
https://www.readbyqxmd.com/read/29184292/cardiopulmonary-rehabilitation-program-impact-on-prognostic-markers-in-selected-patients-with-resting-and-exercise-induced-ventilatory-inefficiency-a-clinical-trial
#9
Sherin Hassan M Mehani, Heba Ahmed A Abdeen
[Purpose] Ventilatory limitation is a common problem in patients with chronic heart failure and pulmonary hypertension. Excess ventilation may arise from augmented ventilatory drive, over activity of chemoreceptors and muscle ergoreceptors, or premature onset of lactic acidosis. Exertional dyspnea can cause limitations in the activities of daily living and as a result, reduced quality of life for these patients. The aim of the present study was to evaluate the effect of cardiopulmonary rehabilitation program on ventilatory efficiency for these patients...
October 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29160099/safety-of-intradiaphragmatic-delivery-of-adeno-associated-virus-mediated-alpha-glucosidase-raav1-cmv-hgaa-gene-therapy-in-children-affected-by-pompe-disease
#10
Manuela Corti, Cristina Liberati, Barbara K Smith, Lee Ann Lawson, Ibrahim S Tuna, Thomas J Conlon, Kirsten E Erger, Saleem Islam, Roland Herzog, David D Fuller, Shelley Collins, Barry J Byrne
We conducted a first in human trial of diaphragmatic gene therapy (AAV1-CMV-GAA) to treat respiratory and neural dysfunction in early-onset Pompe disease. The primary objective of this study was to assess the safety of rAAV1-CMV-hGAA vector delivered to the diaphragm muscle of Pompe disease subjects with ventilatory insufficiency. Safety was assessed by measurement of change in serum chemistries and hematology, urinalysis, and immune response to GAA and AAV as well as change in level of health. Our data demonstrate that the AAV treatment was safe and there were no adverse events related to the study agent...
November 21, 2017: Human Gene Therapy. Clinical Development
https://www.readbyqxmd.com/read/29155335/exercise-testing-in-patients-with-diaphragm-paresis
#11
Tristan Bonnevie, Francis-Edouard Gravier, Agathe Ducrocq, David Debeaumont, Catherine Viacroze, Antoine Cuvelier, Jean-François Muir, Catherine Tardif
PURPOSE: Diaphragm paresis (DP) is characterized by abnormalities of respiratory muscle function. However, the impact of DP on exercise capacity is not well known. This study was performed to assess exercise tolerance in patients with DP and to determine whether inspiratory muscle function was related to exercise capacity, ventilatory pattern and cardiovascular function during exercise. METHODS: This retrospective study included patients with DP who underwent both diaphragmatic force measurements, and cardiopulmonary exercise testing (CPET)...
November 16, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29141527/decreases-in-mixed-venous-blood-o2-saturation-in-cardiac-surgery-patients-following-extubation
#12
Jeffrey Williams, Anna McLean, Jalil Ahari, Arun Jose, Georges Al-Helou, Italo Ibi, Farzad Najam Md, Guillermo Gutierrez
BACKGROUND: Decreases in mixed venous O2 saturation (SvO2) have been reported to occur in postcardiac surgery patients during weaning from mechanical ventilation. Our aim was to establish whether the physiological mechanism responsible for this phenomenon was a decrease in systemic O2 delivery (DO2) or an increase in global O2 consumption ([Formula: see text]O2). METHODS: We studied 21 mechanically ventilated, postoperative cardiac patients for 30 minutes before and 60 minutes after extubation...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29129228/preoperative-low-muscle-mass-has-a-strong-negative-effect-on-pulmonary-function-in-patients-undergoing-living-donor-liver-transplantation
#13
Hisaya Shirai, Toshimi Kaido, Yuhei Hamaguchi, Siyuan Yao, Atsushi Kobayashi, Shinya Okumura, Naoko Kamo, Shintaro Yagi, Hideaki Okajima, Shinji Uemoto
OBJECTIVE: This study investigated the effect of preoperative sarcopenia on cardiopulmonary function in patients undergoing living donor liver transplantation (LDLT). METHODS: A retrospective analysis was performed of 207 patients who underwent LDLT between January 2008 and April 2015. The quantity and quality of skeletal muscle were evaluated by the psoas muscle mass index (PMI) and intramuscular adipose tissue content (IMAC), respectively, using preoperative computed tomography imaging...
January 2018: Nutrition
https://www.readbyqxmd.com/read/29124630/effectiveness-of-inspiratory-muscle-training-on-sleep-and-functional-capacity-to-exercise-in-obstructive-sleep-apnea-a-randomized-controlled-trial
#14
Adília Karoline Ferreira Souza, Armèle Dornelas de Andrade, Ana Irene Carlos de Medeiros, Maria Inês Remígio de Aguiar, Taciano Dias de Souza Rocha, Rodrigo Pinto Pedrosa, Anna Myrna Jaguaribe de Lima
PURPOSE: The aim of this study was to evaluate the effectiveness of inspiratory muscle training (IMT) on sleep and functional capacity to exercise in subjects with obstructive sleep apnea (OSA). METHODS: This is a controlled, randomized, double-blind study conducted in 16 OSA patients divided into two groups: training (IMT: n = 8) and placebo-IMT (P-IMT: n = 8). IMT was conducted during 12 weeks with a moderate load (50-60% of maximal inspiratory pressure-MIP), while P-IMT used a load < 20% of MPI...
November 9, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29119278/development-of-endothermy-in-birds-patterns-and-mechanisms
#15
REVIEW
Edwin R Price, Edward M Dzialowski
Endothermy is a conspicuous and important adaptation in birds. Even though juvenile and adult birds are endothermic and maintain a constant, high body temperature by means of internal heat production, they begin life expressing an ectothermic phenotype. Depending on where a species falls along a continuum of maturity at hatching, from precocial to altricial, they begin to express endothermic traits either close to the time of hatching or as nestlings over a period of 1-3 weeks. Developing endothermy requires attaining a high basal metabolic rate and associated aerobic scope to produce sufficient internal heat, insulation to retain the internally produced heat, and a thermostat that "turns on" heat production in response to cooling ambient temperatures...
November 8, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/29095316/genome-wide-association-study-for-genetic-variants-related-with-maximal-voluntary-ventilation-reveals-two-novel-genomic-signals-associated-with-lung-function
#16
Yujin Suh, Chaeyoung Lee
Genome-wide association studies (GWAS) for spirometry parameters have been limited to forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and their ratio. This study examined to identify genetic variants associated with maximal voluntary ventilation (MVV), an important spirometry parameter presenting inspiratory muscle strength.A total of 8842 Korean subjects participated in the Korean Association REsource Consortium were used to identify nucleotide variants associated with MVV and other spirometry parameters through a GWAS...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29077984/neurally-adjusted-ventilatory-assist-compared-to-other-forms-of-triggered-ventilation-for-neonatal-respiratory-support
#17
REVIEW
Thomas E Rossor, Katie A Hunt, Sandeep Shetty, Anne Greenough
BACKGROUND: Effective synchronisation of infant respiratory effort with mechanical ventilation may allow adequate gas exchange to occur at lower peak airway pressures, potentially reducing barotrauma and volutrauma and development of air leaks and bronchopulmonary dysplasia. During neurally adjusted ventilatory assist ventilation (NAVA), respiratory support is initiated upon detection of an electrical signal from the diaphragm muscle, and pressure is provided in proportion to and synchronous with electrical activity of the diaphragm (EADi)...
October 27, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29077639/short-trail-running-race-beyond-the-classic-model-for-endurance-running-performance
#18
Sabine Ehrström, Marcus P Tartaruga, Christopher S Easthope, Jeanick Brisswalter, Jean-Benoit Morin, Fabrice Vercruyssen
PURPOSE: To examine the extent to which the classical physiological variables of endurance running performance [VO2max, %VO2max at ventilatory threshold (VT), and running economy (RE)], but also muscle strength factors contribute to short trail running (TR) performance. METHODS: A homogeneous group of nine highly-trained trail runners performed an official TR race (27-km) and laboratory-based sessions to determine VO2max, %VO2max at VT, level RE (RE0%) and RE on a +10% slope (RE+10%), voluntary concentric and eccentric knee extension torques (MVCCon and MVCEcc, respectively), local endurance assessed by a fatigue index (FI) and a time to exhaustion at 87...
October 26, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29060280/an-ic-based-controllable-stimulator-for-respiratory-muscle-stimulation-investigations
#19
Jonathan Castelli, Florian Kolbl, Ricardo Siu, Gilles N'Kaoua, Yannick Bornat, Ashwin Mangalore, Brian Hillen, James J Abbas, Sylvie Renaud, Ranu Jung, Noelle Lewis
Functional Electrical Stimulation can be used to restore motor functions loss consecutive to spinal cord injury, such as respiratory deficiency due to paralysis of ventilatory muscles. This paper presents a fully configurable IC-centered stimulator designed to investigate muscle stimulation paradigms. It provides 8 current stimulation channels with high-voltage compliance and real-time operation capabilities, to enable a wide range of FES applications. The stimulator can be used in a standalone mode, or within a closed-loop setup...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29040646/statins-affect-skeletal-muscle-performance-evidence-for-disturbances-in-energy-metabolism
#20
Neeltje A E Allard, Tom J J Schirris, Rebecca J Verheggen, Frans G M Russel, Richard J Rodenburg, Jan A M Smeitink, Paul D Thompson, Maria T E Hopman, Silvie Timmers
Context: Statin myopathy is linked to disturbances in mitochondrial function and exercise intolerance. Objectives: To determine whether differences exist in exercise performance, muscle function and mitochondrial oxidative capacity and content between symptomatic and asymptomatic statin users, and non-statin using controls. Design: Cross-sectional study. Setting: Department of Physiology of the Radboud University Medical Center...
October 9, 2017: Journal of Clinical Endocrinology and Metabolism
keyword
keyword
65031
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"