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https://www.readbyqxmd.com/read/28730223/histopathological-diagnosis-and-its-correlations-with-anatomoclinical-features-surgical-approach-and-postoperative-prognosis-in-sacral-tumors
#1
Oana Ilona David, Corina Veronica Lupaşcu-Ursulescu, Cristian Dumitru Lupaşcu, Aurelia Mihaela Sandu, Victor Dan Eugen Strâmbu, Daniel Alin Cristian, Ştefan Iulian Bedereag, Irina Alexandra Calangea, Elena Violeta Radu, IonuŢ Simion Coman, Vlad Andrei Porojan, Valentin Titus Grigorean
INTRODUCTION: Sacral tumors encompass numerous histopathological types. They represent an uncommon pathology and, when diagnosed, they are often in advanced stage of the disease, becoming a therapeutic challenge. The correct treatment of a sacral tumor should be established by a multidisciplinary team that will assess the exact anatomical, imagistic and histopathological characteristic of the tumors thus choosing an optimal surgical approach while taking into consideration the risk of recurrence...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28729530/achieving-ultrahigh-triboelectric-charge-density-for-efficient-energy-harvesting
#2
Jie Wang, Changsheng Wu, Yejing Dai, Zhihao Zhao, Aurelia Wang, Tiejun Zhang, Zhong Lin Wang
With its light weight, low cost and high efficiency even at low operation frequency, the triboelectric nanogenerator is considered a potential solution for self-powered sensor networks and large-scale renewable blue energy. As an energy harvester, its output power density and efficiency are dictated by the triboelectric charge density. Here we report a method for increasing the triboelectric charge density by coupling surface polarization from triboelectrification and hysteretic dielectric polarization from ferroelectric material in vacuum (P ~ 10(-6) torr)...
July 20, 2017: Nature Communications
https://www.readbyqxmd.com/read/28717662/clinical-and-molecular-characterization-of-cystinuria-in-a-french-cohort-relevance-of-assessing-large-scale-rearrangements-and-splicing-variants
#3
Pascaline Gaildrat, Said Lebbah, Abdellah Tebani, Bénédicte Sudrié-Arnaud, Isabelle Tostivint, Guillaume Bollee, Hélène Tubeuf, Thomas Charles, Aurelia Bertholet-Thomas, Alice Goldenberg, Frederic Barbey, Alexandra Martins, Pascale Saugier-Veber, Thierry Frébourg, Bertrand Knebelmann, Soumeya Bekri
BACKGROUND: Cystinuria is an autosomal recessive disorder of dibasic amino acid transport in the kidney and the intestine leading to increased urinary cystine excretion and nephrolithiasis. Two genes, SLC3A1 and SLC7A9, coding respectively for rBAT and b0,+AT, account for the genetic basis of cystinuria. METHODS: This study reports the clinical and molecular characterization of a French cohort including 112 cystinuria patients and 25 relatives from 99 families. Molecular screening was performed using sequencing and Quantitative Multiplex PCR of Short Fluorescent Fragments analyses...
July 2017: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/28709699/strategy-to-identify-subjects-with-diabetes-mellitus-more-suitable-for-selective-echocardiographic-screening-the-david-berg-study
#4
Mauro Gori, Paolo Canova, Alice Calabrese, Giovanni Cioffi, Roberto Trevisan, Renata De Maria, Aurelia Grosu, Attilio Iacovoni, Alessandra Fontana, Paola Ferrari, Stephen J Greene, Mihai Gheorghiade, Gianfranco Parati, Antonello Gavazzi, Michele Senni
BACKGROUND: Despite the burden of pre-clinical heart failure (HF) among diabetes mellitus (DM) patients, routine screening echocardiography is not currently recommended. We prospectively assessed risk prediction for HF/death of a screening strategy combining clinical data, electrocardiogram, NTproBNP, and echocardiogram, aiming to identify DM patients more suitable for selective echocardiography. METHODS: Among 4047 screened subjects aged≥55/≤80years, the DAVID-Berg Study prospectively enrolled 623 outpatients with DM, or hypertension, or known cardiovascular disease but with no HF history/symptoms...
June 28, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28705104/asymptomatic-giant-right-atrial-appendage-aneurysm-a-7-year-follow-up
#5
Martin Chaumont, Aurélia David-Cojocariu, Kaies Akkari, Dominique Schulze, Philippe Unger
No abstract text is available yet for this article.
July 14, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28702015/inhibition-of-the-rumen-ciliate-entodinium-caudatum-by-antibiotics
#6
Tansol Park, Tea Meulia, Jeffrey L Firkins, Zhongtang Yu
Axenic cultures of free-living aerobic ciliates, such as Tetrahymena thermophila and Paramecium aurelia, have been established and routinely used in laboratory research, greatly facilitating, or enabling characterization of their metabolism, physiology, and ecology. Ruminal protozoa are anaerobic ciliates, and they play important roles in feed digestion and fermentation. Although, repeatedly attempted, no laboratory-maintainable axenic culture of ruminal ciliates has been established. When axenic ciliate cultures are developed, antibiotics are required to eliminate the accompanying bacteria...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28700435/ifitm1-outperforms-cd10-in-differentiating-low-grade-endometrial-stromal-sarcomas-from-smooth-muscle-neoplasms-of-the-uterus
#7
Aurelia Busca, Previn Gulavita, Carlos Parra-Herran, Shahidul Islam
Distinguishing between uterine neoplasms of smooth muscle and endometrial stromal origin is a frequent diagnostic challenge. We investigated the staining pattern of interferon-induced transmembrane protein-1 (IFITM1), a novel endometrial stromal marker, in endometrial and smooth muscle uterine neoplasms and compared it with CD10 in its ability to differentiate between these two groups. Immunohistochemistry for IFITM1 and CD10 was performed in 20 cases of smooth muscle neoplasms (10 cases leiomyoma, 10 cases leiomyosarcoma), 14 cases of endometrial stromal sarcoma (ESS) (12 cases of low grade and 2 cases of high grade) and 12 cases of carcinosarcoma...
July 11, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28693355/postsorafenib-systemic-treatments-for-hepatocellular-carcinoma-questions-and-opportunities-after-the-regorafenib-trial
#8
Francesco Tovoli, Stefania De Lorenzo, Maria Aurelia Barbera, Ingrid Garajova, Giorgio Frega, Andrea Palloni, Maria Abbondanza Pantaleo, Guido Biasco, Giovanni Brandi
The search for systemic therapies for hepatocellular carcinoma has been characterized by difficulties and failures. Despite recent progresses, many issues are still to be settled. In particular, the development of drugs inhibiting different neoplastic pathways remains a priority for patients intolerant or resistant to antiangiogenic drugs. This task may be daunting, as previous failures extensively demonstrated. We aimed to identify the future perspective of postsorafenib trials analyzing the strengths and the critical points of past and currently undergoing studies, in the light of the most recent evidences in the field...
July 11, 2017: Future Oncology
https://www.readbyqxmd.com/read/28690584/decompression-in-chiari-malformation-clinical-ocular-motor-cerebellar-and-vestibular-outcome
#9
Nicolina Goldschagg, Katharina Feil, Franziska Ihl, Siegbert Krafczyk, Mathias Kunz, Jörg Christian Tonn, Michael Strupp, Aurelia Peraud
BACKGROUND: Treatment of Chiari malformation can include suboccipital decompression with resection of one cerebellar tonsil. Its effects on ocular motor and cerebellar function have not yet been systematically examined. OBJECTIVE: To investigate whether decompression, including resection of one cerebellar tonsil, leads to ocular motor, vestibular, or cerebellar deficits. PATIENTS AND METHODS: Ten patients with Chiari malformation type 1 were systematically examined before and after (1 week and 3 months) suboccipital decompression with unilateral tonsillectomy...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28689295/inhibitory-rtms-applied-on-somatosensory-cortex-in-wilson-s-disease-patients-with-hand-dystonia
#10
Pierre Lozeron, Aurélia Poujois, Elodie Meppiel, Sana Masmoudi, Thierry Peron Magnan, Eric Vicaut, Emmanuel Houdart, Jean-Pierre Guichard, Jean-Marc Trocello, France Woimant, Nathalie Kubis
Hand dystonia is a common complication of Wilson's disease (WD), responsible for handwriting difficulties and disability. Alteration of sensorimotor integration and overactivity of the somatosensory cortex have been demonstrated in dystonia. This study investigated the immediate after effect of an inhibitory repetitive transcranial magnetic stimulation (rTMS) applied over the somatosensory cortex on the writing function in WD patients with hand dystonia. We performed a pilot prospective randomized double-blind sham-controlled crossover rTMS study...
July 8, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28673276/worldwide-view-of-nephropathic-cystinosis-results-from-a-survey-from-30-countries
#11
Aurélia Bertholet-Thomas, Julien Berthiller, Velibor Tasic, Behrouz Kassai, Hasan Otukesh, Marcella Greco, Jochen Ehrich, Rejane de Paula Bernardes, Georges Deschênes, Sally-Ann Hulton, Michel Fischbach, Kenza Soulami, Bassam Saeed, Ehsan Valavi, Carlos Jose Cobenas, Bülent Hacihamdioglu, Gabrielle Weiler, Pierre Cochat, Justine Bacchetta
BACKGROUND: Nephropathic cystinosis is a rare inherited metabolic disorder leading to progressive renal failure and extra-renal comorbidity. The prognosis relies on early adherence to cysteamine treatment and symptomatic therapies. Developing nations [DiN] experience many challenges for management of cystinosis. The aim of this study was to assess the management characteristics in DiN compared with developed nations [DeN]. METHODS: A questionnaire was sent between April 2010 and May 2011 to 87 members of the International Pediatric Nephrology Association, in 50 countries...
July 3, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28670906/feasibility-and-acceptability-of-a-mediterranean-style-diet-intervention-to-reduce-cardiovascular-risk-for-low-income-hispanic-american-women
#12
Yaniré Estrada Del Campo, Laura Cubillos, Maihan B Vu, Aurelia Aguirre, Daniel S Reuland, Thomas C Keyserling
OBJECTIVE: Evidence for the cardioprotective effects of a Mediterranean-style (Med-style) diet is strong, however few Med-style dietary interventions have been developed for and tested among Hispanic Americans (HAs), especially younger HAs of reproductive age whose dietary habits may strongly influence dietary intake for all family members. DESIGN: We adapted a previously tested and evidence-informed lifestyle intervention to reduce CVD risk and evaluated its feasibility, acceptability, and effects on self-reported lifestyle behaviors in this study enrolling low-income HA women attending a Title X family planning clinic in eastern North Carolina...
July 1, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28665853/review-of-surgical-education-and-health-care-reform-defining-the-role-and-value-of-trainees-in-an-evolving-medical-landscape-by-fayanju-om-aggarwal-r-baucom-rb-ferrone-cr-massaro-d-terhune-kp-in-ann-surg-265-459-460-2017
#13
https://www.readbyqxmd.com/read/28665844/review-of-mastery-of-care-toward-communitarian-regulation-by-pronovost-p-and-higgins-rs-in-ann-surg-265-271-272-2017
#14
Kristina P Marsack, Aurelia T Perdanasari, Larry H Hollier
No abstract text is available yet for this article.
June 29, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28664868/observations-on-non-random-distribution-of-spores-of-henneguya-spp-cnidaria-myxosporea-myxobolidae-within-plasmodia
#15
Jorge C Eiras, Manuel Cruz, Cristina Cruz, Aurelia Saraiva, Edson A Adriano, Csaba Szekely, Kalman Molnar
Species of the cnidarian genus Henneguya Thélohan, 1892 (Myxosporea: Myxobolidae) are histozoic parasites commonly found in freshwater and, more rarely, in marine fish. The development of these parasites in fish tissues includes the formation of plasmodia within which occurs the sporogony originating spores with two caudal processes, which are usually randomly distributed within the plasmodia. In this report the authors present some cases of non-random distribution of the spores of six species of Henneguya within their plasmodia...
June 20, 2017: Folia Parasitologica
https://www.readbyqxmd.com/read/28651633/improved-methods-and-resources-for-paramecium-genomics-transcription-units-gene-annotation-and-gene-expression
#16
Olivier Arnaiz, Erwin Van Dijk, Mireille Bétermier, Maoussi Lhuillier-Akakpo, Augustin de Vanssay, Sandra Duharcourt, Erika Sallet, Jérôme Gouzy, Linda Sperling
BACKGROUND: The 15 sibling species of the Paramecium aurelia cryptic species complex emerged after a whole genome duplication that occurred tens of millions of years ago. Given extensive knowledge of the genetics and epigenetics of Paramecium acquired over the last century, this species complex offers a uniquely powerful system to investigate the consequences of whole genome duplication in a unicellular eukaryote as well as the genetic and epigenetic mechanisms that drive speciation. High quality Paramecium gene models are important for research using this system...
June 26, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28649426/conserved-and-species-specific-molecular-denominators-in-mammalian-skeletal-muscle-aging
#17
Evi M Mercken, Miriam Capri, Bethany A Carboneau, Maria Conte, Juliana Heidler, Aurelia Santoro, Alejandro Martin-Montalvo, Marta Gonzalez-Freire, Husam Khraiwesh, José A González-Reyes, Ruin Moaddel, Yongqing Zhang, Kevin G Becker, José M Villalba, Julie A Mattison, Ilka Wittig, Claudio Franceschi, Rafael de Cabo
Aging is a complex phenomenon involving functional decline in multiple physiological systems. We undertook a comparative analysis of skeletal muscle from four different species, i.e. mice, rats, rhesus monkeys, and humans, at three different representative stages during their lifespan (young, middle, and old) to identify pathways that modulate function and healthspan. Gene expression profiling and computational analysis revealed that pathway complexity increases from mice to humans, and as mammals age, there is predominantly an upregulation of pathways in all species...
2017: NPJ Aging and Mechanisms of Disease
https://www.readbyqxmd.com/read/28648494/characteristics-and-prevalence-of-wilson-s-disease-a-2013-observational-population-based-study-in-france
#18
Aurélia Poujois, France Woimant, Solène Samson, Pascal Chaine, Nadège Girardot-Tinant, Philippe Tuppin
BACKGROUND AND AIMS: Only a few epidemiological studies on the incidence and prevalence of Wilson's disease (WD) have been performed to date, and the results vary widely according to the reports. The aim of the study was to investigate the prevalence, ambulatory care and treatments of patients with WD in France. METHODS: Among the 58 million general health scheme beneficiaries (86% of the French population), people managed for WD in 2013 were identified using hospitalisation diagnosis in 2011-2013 or specific long-term disease status with a 100% reimbursement for specific healthcare in 2013...
June 22, 2017: Clinics and Research in Hepatology and Gastroenterology
https://www.readbyqxmd.com/read/28648188/-the-humanistic-partnership-model-in-health-care
#19
REVIEW
Dan Lecocq, Hélène Lefebvre, André Néron, Chantal Van Cutsem, Aurélia Bustillo, Martine Laloux
The humanistic partnership model in health care has been jointly developed by nursing professionals and partner patients. In line with the evolution of our society and nursing thinking, it provides a new implementation of the discipline's core concepts and invites professionals and partner patients to "move together towards" a co-constructed future which is recorded in the patient's life project.
June 2017: Soins; la Revue de Référence Infirmière
https://www.readbyqxmd.com/read/28641483/good-performance-of-platinum-based-chemotherapy-for-high-grade-gastroenteropancreatic-and-unknown-primary-neuroendocrine-neoplasms
#20
Giovanni Brandi, Marco Paragona, Davide Campana, Nicole Brighi, Arrigo Bondi, Maria Abbondanza Pantaleo, Jody Corbelli, Maria Aurelia Barbera, Guido Biasco
To evaluate efficacy and safety of platinum and etoposide combination in the treatment of advanced gastroenteropancreatic (GEP) and unknown primary (CUP) neuroendocrine carcinomas (NEC), we analysed the records of 21 consecutive patients treated with this regimen from 1999 to 2012. Objective responses were obtained in 11 patients (52%) and disease stability (DS) in 5 (24%). Median progression-free survival (PFS) was 7 months (95% CI, 5.33-8.66). Median overall survival (OS) was 16 months (95% CI, 14.97-17...
June 22, 2017: Journal of Chemotherapy
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