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https://www.readbyqxmd.com/read/28343460/new-methods-of-morphometric-analyses-on-scyphozoan-jellyfish-statoliths-including-the-first-direct-evidence-for-statolith-growth-using-calcein-as-a-fluorescent-marker
#1
Ilka Sötje, Tamar Dishon, Frank Hoffmann, Sabine Holst
Statoliths are the only hard structures in the gelatinous bell of most scyphozoan medusae and investigations on these structures could promote investigations of the understudied population dynamics and phylogeny of jellyfish. We examined the statoliths of Aurelia aurita jellyfish of different ages by light microscopic and microtomographic measurements supplemented by scanning electron microscopy. The morphometric analyses confirmed that statolith numbers and sizes increase during jellyfish development and revealed that newly-formed statoliths had similar shapes that may change during statolith growth...
March 27, 2017: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/28335173/mid-term-results-of-femoro-popliteal-stenting-for-chronic-critical-ischemia
#2
Aurélia Bianchini, Damien Labbe, Hovan Chenorhokian, Céline Perot-Millet, David Massouille
No abstract text is available yet for this article.
January 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28335171/mid-term-results-of-femoro-popliteal-stenting-among-patients-presenting-early-atheromatous-lesions-of-the-lower-extremities
#3
Damien Labbe, Aurélia Bianchini, Céline Perot, Hélène Wattez, David Massouille
No abstract text is available yet for this article.
January 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28334824/annexin-a2-links-poor-myofiber-repair-with-inflammation-and-adipogenic-replacement-of-the-injured-muscle
#4
Aurelia Defour, Sushma Medikayala, Jack H Van der Meulen, Marshall W Hogarth, Nicholas Holdreith, Apostolos Malatras, William Duddy, Jessica Boehler, Kanneboyina Nagaraju, Jyoti K Jaiswal
Repair of skeletal muscle after sarcolemmal damage involves dysferlin and dysferlin-interacting proteins such as annexins. Mice and patient lacking dysferlin exhibit chronic muscle inflammation and adipogenic replacement of the myofibers. Here we show that similar to dysferlin, lack of annexin A2 (AnxA2) also results in poor myofiber repair and progressive muscle weakening with age. By longitudinal analysis of AnxA2-deficient muscle we find that poor myofiber repair due to the lack of AnxA2 does not result in chronic inflammation or adipogenic replacement of the myofibers...
February 21, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28329758/lactb-is-a-tumour-suppressor-that-modulates-lipid-metabolism-and-cell-state
#5
Zuzana Keckesova, Joana Liu Donaher, Jasmine De Cock, Elizaveta Freinkman, Susanne Lingrell, Daniel A Bachovchin, Brian Bierie, Verena Tischler, Aurelia Noske, Marian C Okondo, Ferenc Reinhardt, Prathapan Thiru, Todd R Golub, Jean E Vance, Robert A Weinberg
Post-mitotic, differentiated cells exhibit a variety of characteristics that contrast with those of actively growing neoplastic cells, such as the expression of cell-cycle inhibitors and differentiation factors. We hypothesized that the gene expression profiles of these differentiated cells could reveal the identities of genes that may function as tumour suppressors. Here we show, using in vitro and in vivo studies in mice and humans, that the mitochondrial protein LACTB potently inhibits the proliferation of breast cancer cells...
March 22, 2017: Nature
https://www.readbyqxmd.com/read/28327832/-frequency-of-metabolic-syndrome-in-residents-of-an-andean-region-in-peru
#6
Juana Aurelia Ninatanta-Ortiz, Luz Amparo Núñez-Zambrano, Segunda Aydeé García-Flores, Franco Romaní Romaní
Objectives.: To calculate the frequency of metabolic syndrome (MetS) and its associated characteristics in selected populations residing in the urban areas of two districts in the Cajamarca region. Materials and methods.: Cross-sectional study performed in 2014, obtaining randomized samples from three target study populations: high school students, university students, and schoolchildren mothers. In adults, MetS was defined by means of Third Adult Treatment Panel (ATP III) criteria, and in teenagers, the modified Cook criteria were used...
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28327577/metabolic-profiling-of-idh-mutation-and-malignant-progression-in-infiltrating-glioma
#7
Llewellyn E Jalbert, Adam Elkhaled, Joanna J Phillips, Evan Neill, Aurelia Williams, Jason C Crane, Marram P Olson, Annette M Molinaro, Mitchel S Berger, John Kurhanewicz, Sabrina M Ronen, Susan M Chang, Sarah J Nelson
Infiltrating low grade gliomas (LGGs) are heterogeneous in their behavior and the strategies used for clinical management are highly variable. A key factor in clinical decision-making is that patients with mutations in the isocitrate dehydrogenase 1 and 2 (IDH1/2) oncogenes are more likely to have a favorable outcome and be sensitive to treatment. Because of their relatively long overall median survival, more aggressive treatments are typically reserved for patients that have undergone malignant progression (MP) to an anaplastic glioma or secondary glioblastoma (GBM)...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28326893/psycholinguistic-norms-for-320-fixed-expressions-idioms-and-proverbs-in-french
#8
Patrick Bonin, Alain Méot, Jean-Michel Boucheix, Aurélia Bugaiska
We provide psycholinguistic norms for a new set of 160 French idiomatic expressions and 160 proverbs: knowledge, predictability, literality, compositionality, subjective and objective frequency, familiarity, age of acquisition (AoA), and length. Different analyses (reliability, descriptive statistics, correlations) performed on the norms are reported and discussed. The norms can be downloaded as supplemental material.
March 22, 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/28320345/effect-of-telephone-follow-up-on-repeated-suicide-attempt-in-patients-discharged-from-an-emergency-psychiatry-department-a-controlled-study
#9
Sophie Exbrayat, Clotilde Coudrot, Xavier Gourdon, Aurélia Gay, Jessica Sevos, Jacques Pellet, Béatrice Trombert-Paviot, Catherine Massoubre
BACKGROUND: Attempted suicide is a major public health problem, and the efficacies of current postvention protocols vary. We evaluated the effectiveness of telephone follow-up of patients referred to an emergency psychiatric unit for attempted suicide on any further attempt/s over the following year. METHOD: In a single-center, controlled study with intent to treat, we evaluated the efficacy of a protocol of telephone follow-up of 436 patients at 8, 30, and 60 days after they were treated for attempted suicide...
March 20, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28303748/do-animacy-effects-persist-in-memory-for-context
#10
Margaux Gelin, Patrick Bonin, Alain Méot, Aurélia Bugaiska
The adaptive view of human memory (Nairne, 2010) assumes that animates (e.g., rabbit) are remembered better than inanimates (e.g., glass) because animates are ultimately more important for fitness than inanimates. Previous studies provided evidence for this view by showing that animates were recalled or recognized better than inanimates (e.g., Nairne, VanArsdall, Pandeirada, Cogdill, & LeBreton, 2013), but they did not assess memory for contextual details (e.g., where animates vs. inanimates occurred). In this study, we tested recollection of spatial information (Study 1) and temporal information (Study 2) associated with animate versus inanimate words...
March 17, 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/28298967/magnetic-resonance-imaging-in-the-assessment-of-brain-involvement-in-alcoholic-and-nonalcoholic-wernicke-s-encephalopathy
#11
Gianvincenzo Sparacia, Andrea Anastasi, Claudia Speciale, Francesco Agnello, Aurelia Banco
AIM: To present the typical and atypical magnetic resonance (MR) imaging findings of alcoholic and non-alcoholic Wernicke's encephalopathy. METHODS: This study included 7 patients with Wernicke's encephalopathy (2 men, 5 women; mean age, 52.3 years) that underwent brain MR examination between January 2012 and March 2016 in a single institution. Three patients were alcoholics and 4 patients were non-alcoholics. MR protocol included a T2-weighted sequence, a fluid attenuation inversion recovery (FLAIR) sequence, a diffusion-weighted sequence (b = 0 and 1000 s/mm(2)), and a contrast-enhanced MR sequence...
February 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28291545/adding-bevacizumab-to-single-agent-chemotherapy-for-the-treatment-of-platinum-resistant-recurrent-ovarian-cancer-a-cost-effectiveness-analysis-of-the-aurelia-trial
#12
Weiya Z Wysham, Elisabeth M Schaffer, Theresa Coles, Dario R Roque, Stephanie B Wheeler, Kenneth H Kim
OBJECTIVE: AURELIA, a randomized phase III trial of adding bevacizumab (B) to single agent chemotherapy (CT) for the treatment of platinum-resistant recurrent ovarian cancer, demonstrated improved progression free survival (PFS) in the B+CT arm compared to CT alone. We aimed to evaluate the cost effectiveness of adding B to CT in the treatment of platinum-resistant recurrent ovarian cancer. METHODS: A decision tree model was constructed to evaluate the cost effectiveness of adding bevacizumab (B) to single agent chemotherapy (CT) based on the arms of the AURELIA trial...
March 10, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28285131/retrieval-under-stress-decreases-the-long-term-expression-of-a-human-declarative-memory-via-reconsolidation
#13
Pablo Nicolás Fernández Larrosa, Alejandro Ojea, Ignacio Ojea, Victor Alejandro Molina, María Aurelia Zorrilla-Zubilete, Alejandro Delorenzi
Acute stress impairs memory retrieval of several types of memories. An increase in glucocorticoids, several minutes after stressful events, is described as essential to the impairing retrieval-effects of stressors. Moreover, memory retrieval under stress can have long-term consequences. Through what process does the reactivated memory under stress, despite the disrupting retrieval effects, modify long-term memories? The reconsolidation hypothesis proposes that a previously consolidated memory reactivated by a reminder enters a vulnerability phase (labilization) during which it is transiently sensitive to modulation, followed by a re-stabilization phase...
March 8, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28284480/copy-number-variations-found-in-patients-with-a-corpus-callosum-abnormality-and-intellectual-disability
#14
Solveig Heide, Boris Keren, Thierry Billette de Villemeur, Sandra Chantot-Bastaraud, Christel Depienne, Caroline Nava, Cyril Mignot, Aurélia Jacquette, Eric Fonteneau, Elodie Lejeune, Corinne Mach, Isabelle Marey, Sandra Whalen, Didier Lacombe, Sophie Naudion, Caroline Rooryck, Annick Toutain, Cédric Le Caignec, Damien Haye, Laurence Olivier-Faivre, Alice Masurel-Paulet, Christel Thauvin-Robinet, Fabien Lesne, Anne Faudet, Dorothée Ville, Vincent des Portes, Damien Sanlaville, Jean-Pierre Siffroi, Marie-Laure Moutard, Delphine Héron
OBJECTIVE: To evaluate the role that chromosomal micro-rearrangements play in patients with both corpus callosum abnormality and intellectual disability, we analyzed copy number variations (CNVs) in patients with corpus callosum abnormality/intellectual disability STUDY DESIGN: We screened 149 patients with corpus callosum abnormality/intellectual disability using Illumina SNP arrays. RESULTS: In 20 patients (13%), we have identified at least 1 CNV that likely contributes to corpus callosum abnormality/intellectual disability phenotype...
March 8, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28279672/erratum-to-predominance-of-healthcare-associated-cases-among-episodes-of-community-onset-bacteraemia-due-to-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-international-journal-of-antimicrobial-agents-49-1-67-73
#15
Jean-Ralph Zahar, Philippe Lesprit, Stephane Ruckly, Aurelia Eden, Hitoto Hikombo, Louis Bernard, Stephan Harbarth, Jean-Francois Timsit, Christian Brun-Buisson
No abstract text is available yet for this article.
March 6, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28276434/extracellular-proteasome-osteopontin-circuit-regulates-cell-migration-with-implications-in-multiple-sclerosis
#16
Chiara Dianzani, Elena Bellavista, Juliane Liepe, Claudia Verderio, Morena Martucci, Aurelia Santoro, Annalisa Chiocchetti, Casimiro Luca Gigliotti, Elena Boggio, Benedetta Ferrara, Loredana Riganti, Christin Keller, Katharina Janek, Agathe Niewienda, Chiara Fenoglio, Melissa Sorosina, Roberto Cantello, Peter M Kloetzel, Michael P H Stumpf, Friedemann Paul, Klemens Ruprecht, Daniela Galimberti, Filippo Martinelli Boneschi, Cristoforo Comi, Umberto Dianzani, Michele Mishto
Osteopontin is a pleiotropic cytokine that is involved in several diseases including multiple sclerosis. Secreted osteopontin is cleaved by few known proteases, modulating its pro-inflammatory activities. Here we show by in vitro experiments that secreted osteopontin can be processed by extracellular proteasomes, thereby producing fragments with novel chemotactic activity. Furthermore, osteopontin reduces the release of proteasomes in the extracellular space. The latter phenomenon seems to occur in vivo in multiple sclerosis, where it reflects the remission/relapse alternation...
March 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28275108/maternal-high-fat-diet-in-mice-leads-to-innate-airway-hyperresponsiveness-in-the-adult-offspring
#17
Kelvin D MacDonald, Aurelia R Moran, Ashley J Scherman, Cindy T McEvoy, Astrid S Platteau
Maternal obesity prior to and during pregnancy has been associated with an increased incidence of childhood asthma. As diets rich in saturated fat are linked to obesity and inflammation, we created a murine model to investigate the effect of maternal high-fat diet (HFD) on adult offspring airway hyperreactivity (AHR), a cardinal feature of asthma. Balb/cByJ dams were fed a HFD (60% fat Calories) or normal-fat diet (NFD) (10% fat Calories) from 8 weeks prior to first breeding through their pregnancies. Pups were weaned to either a HFD or NFD (at 4 weeks of age)...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28265497/indomethacin-reproducibly-induces-metamorphosis-in-cassiopea-xamachana-scyphistomae
#18
Patricia Cabrales-Arellano, Tania Islas-Flores, Patricia E Thomé, Marco A Villanueva
Cassiopea xamachana jellyfish are an attractive model system to study metamorphosis and/or cnidarian-dinoflagellate symbiosis due to the ease of cultivation of their planula larvae and scyphistomae through their asexual cycle, in which the latter can bud new larvae and continue the cycle without differentiation into ephyrae. Then, a subsequent induction of metamorphosis and full differentiation into ephyrae is believed to occur when the symbionts are acquired by the scyphistomae. Although strobilation induction and differentiation into ephyrae can be accomplished in various ways, a controlled, reproducible metamorphosis induction has not been reported...
2017: PeerJ
https://www.readbyqxmd.com/read/28251922/early-stages-of-functional-diversification-in-the-rab-gtpase-gene-family-revealed-by-genomic-and-localization-studies-in-paramecium-species
#19
Lydia J Bright, Jean-Francois Gout, Michael Lynch
New gene functions arise within existing gene families as a result of gene duplication and subsequent diversification. To gain insight into the steps that lead to the functional diversification of paralogs, we tracked duplicate retention patterns, expression-level divergence, and subcellular markers of functional diversification in the Rab GTPase gene family in three Paramecium aurelia species. Following whole genome duplication, Rab GTPase duplicates are more highly retained than other genes in the genome, but appear to be diverging more rapidly in expression levels, consistent with early steps in functional diversification...
March 1, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28250714/the-effect-of-core-and-lanthanide-ion-dopants-in-sodium-fluoride-based-nanocrystals-on-phagocytic-activity-of-human-blood-leukocytes
#20
Bartlomiej Sojka, Aurelia Liskova, Miroslava Kuricova, Mateusz Banski, Jan Misiewicz, Maria Dusinska, Mira Horvathova, Silvia Ilavska, Michaela Szabova, Eva Rollerova, Artur Podhorodecki, Jana Tulinska
Sodium fluoride-based β-NaLnF4 nanoparticles (NPs) doped with lanthanide ions are promising materials for application as luminescent markers in bio-imaging. In this work, the effect of NPs doped with yttrium (Y), gadolinium (Gd), europium (Eu), thulium (Tm), ytterbium (Yb) and terbium (Tb) ions on phagocytic activity of monocytes and granulocytes and the respiratory burst was examined. The surface functionalization of <10-nm NPs was performed according to our variation of patent pending ligand exchange method that resulted in meso-2,3-dimercaptosuccinic acid (DMSA) molecules on their surface...
2017: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
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