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https://www.readbyqxmd.com/read/29684912/cementum-regeneration-using-stem-cells-in-the-dog-model-a-systematic-review
#1
REVIEW
Jacqueline Crossman, Maryam Elyasi, Tarek El-Bialy, Carlos Flores Mir
OBJECTIVE: Restoring lost tissues of the periodontium, such as cementum, is essential in reducing the risk of tooth loss due to periodontitis and/or severe root resorption. Stem cell therapy is a regenerative strategy in cementum regeneration. This systematic review aimed to analyze the effect of various stem cells and their transplantation method on cementum regeneration in the dog model. METHODS: Electronic databases were searched, in addition to performing hand searches and a gray literature search...
April 3, 2018: Archives of Oral Biology
https://www.readbyqxmd.com/read/29684844/consumer-acceptance-of-cultured-meat-a-systematic-review
#2
REVIEW
Christopher Bryant, Julie Barnett
Cultured meat grown in-vitro from animal cells is being developed as a way of addressing many of the ethical and environmental concerns associated with conventional meat production. As commercialisation of this technology appears increasingly feasible, there is growing interest in the research on consumer acceptance of cultured meat. We present a systematic review of the peer-reviewed literature, and synthesize and analyse the findings of 14 empirical studies. We highlight demographic variations in consumer acceptance, factors influencing acceptance, common consumer objections, perceived benefits, and areas of uncertainty...
April 12, 2018: Meat Science
https://www.readbyqxmd.com/read/29684790/is-there-evidence-to-use-kinematic-kinetic-measures-clinically-in-low-back-pain-patients-a-systematic-review
#3
REVIEW
Enrica Papi, Anthony M J Bull, Alison H McGregor
BACKGROUND: Currently, there is a widespread reliance on self-reported questionnaires to assess low back pain patients. However, it has been suggested that objective measures of low back pain patients' functional status should be used to aid clinical assessment. The aim of this study is to systematically review which kinematic /kinetic parameters have been used to assess low back pain patients against healthy controls and to propose clinical kinematic/kinetic measures. METHODS: PubMed, Embase and Scopus databases were searched for relevant studies...
April 11, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/29684747/the-possible-dna-damage-induced-by-environmental-organic-compounds-the-case-of-nonylphenol
#4
REVIEW
Zahra Noorimotlagh, Seyyed Abbas Mirzaee, Mehdi Ahmadi, Neemat Jaafarzadeh, Fakher Rahim
Human impact on the environment leads to the release of many pollutants that produce artificial compounds, which can have harmful effects on the body's endocrine system; these are known as endocrine disruptors (EDs). Nonylphenol (NP) is a chemical compound with a nonyl group that is attached to a phenol ring. NP-induced H2 AX is a sensitive genotoxic biomarker for detecting possible DNA damage; it also causes male infertility and carcinogenesis. We attempt to comprehensively review all the available evidence about the different ways with descriptive mechanisms for explaining the possible DNA damage that is induced by NP...
April 20, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29684702/prospective-environmental-risk-assessment-of-mixtures-in-wastewater-treatment-plant-effluents-theoretical-considerations-and-experimental-verification
#5
Anja Coors, Pia Vollmar, Frank Sacher, Christian Polleichtner, Enken Hassold, Daniela Gildemeister, Ute Kühnen
The aquatic environment is continually exposed to a complex mixture of chemicals, whereby effluents of wastewater treatment plants (WWTPs) are one key source. The aim of the present study was to investigate whether environmental risk assessments (ERAs) addressing individual substances are sufficiently protective for such coincidental mixtures. Based on a literature review of chemicals reported to occur in municipal WWTP effluents and mode-of-action considerations, four different types of mixtures were composed containing human pharmaceuticals, pesticides, and chemicals regulated under REACH...
April 14, 2018: Water Research
https://www.readbyqxmd.com/read/29684669/the-impact-of-associated-injuries-and-fracture-classifications-on-the-treatment-of-capitellum-and-trochlea-fractures-a-systematic-review-and-meta-analysis
#6
REVIEW
Shu-Kun He, Long Xu, Jin-Hai Guo, Jing-Ping Liao, Ting-Wu Qin, Fu-Guo Huang
BACKGROUND: Capitellum and trochlea fractures are truly rare and the treatment is not fully appreciated. So we evaluate the impact of associated injuries and fracture classifications on elbow functional outcomes after open reduction and internal fixation. MATERIALS AND METHODS: PubMed, Embase, Ovid Medline, and the Cochrane Library were searched from January 1, 1974 to January 1, 2017. All English literature with the treatment of capitellum and trochlea fractures by open reduction and internal fixation were included...
April 20, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29684634/interactive-electronic-decision-trees-for-the-integrated-primary-care-management-of-febrile-children-in-low-resource-settings-review-of-existing-tools
#7
REVIEW
Kristina Keitel, Valérie D'Acremont
BACKGROUND: The lack of effective, integrated diagnostic tools pose a major challenge to the primary care management of febrile childhood illnesses. These limitations are especially evident in low-resource settings and are often inappropriately compensated by antimicrobial over-prescription. Interactive electronic decision trees (IEDTs) have the potential to close these gaps: guiding antibiotic use and better identifying serious disease. AIMS: This narrative review summarizes existing IEDTs, to provide an overview of their degree of validation, as well as to identify gaps in current knowledge and prospects for future innovation...
April 20, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29684571/cryoballoon-best-practices-ii-practical-guide-to-procedural-monitoring-and-dosing-during-atrial-fibrillation-ablation-from-the-perspective-of-experienced-users
#8
Wilber Su, Arash Aryana, Rod Passman, Gurjit Singh, Robert Hokanson, Marcin Kowalski, Jason Andrade, Paul Wang
Since cryoballoon was evaluated in STOP-AF, over 350,000 patients with AF have been treated. Several studies have reported improved outcomes using the second-generation cryoballoon, and recent publications have evaluated modifications, refinements, and improvements to procedural techniques. Here, peer-reviewed manuscripts published since the first cryoballoon best practices review were summarized against the technical practices of physicians with a high-level of experience with the cryoballoon (average ≥6 years of experience in ≥900 cases)...
April 20, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29684528/oligomerization-and-cooperativity-in-gpcrs-from-the-perspective-of-the-angiotensin-at1-and-dopamine-d2-receptors
#9
REVIEW
Serdar Durdagi, Ismail Erol, Ramin Ekhteiari Salmas, Busecan Aksoydan, Isik Kantarcioglu
G Protein-Coupled Receptors (GPCRs) can form homodimer or constitute heterodimer/higher oligomeric clusters with other heptahelical GPCRs. In this article, multiscale molecular modeling approaches as well as experimental techniques which are used to study oligomerization of GPCRs are reviewed. In particular, the effect of dimerization/oligomerization to the ligand binding affinity of individual protomers and also on the efficacy of the oligomer are discussed by including diverse examples from the literature...
April 20, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29684521/the-hypoxic-peri-arteriolar-glioma-stem-cell-niche-an-integrated-concept-of-five-types-of-niches-in-human-glioblastoma
#10
REVIEW
Diana A Aderetti, Vashendriya V V Hira, Remco J Molenaar, Cornelis J F van Noorden
Glioblastoma is the most lethal primary brain tumor and poor survival of glioblastoma patients is attributed to the presence of glioma stem cells (GSCs). These therapy-resistant, quiescent and pluripotent cells reside in GSC niches, which are specific microenvironments that protect GSCs against radiotherapy and chemotherapy. We previously showed the existence of hypoxic peri-arteriolar GSC niches in glioblastoma tumor samples. However, other studies have described peri-vascular niches, peri-hypoxic niches, peri-immune niches and extracellular matrix niches of GSCs...
April 20, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29684517/nickel-related-adverse-reactions-in-the-treatment-of-cerebral-aneurysms-a-literature-review
#11
REVIEW
Anderson Chun On Tsang, Patrick Nicholson, Vitor Mendes Pereira
BACKGROUND: Nickel is the most common metal allergen and predominantly affects women. It is also the ubiquitous component in the alloys used to manufacture intracranial devices for aneurysm treatments, including aneurysm clips, self-expanding stents, flow-diverting stents and endosaccular occlusion devices. Adverse events related to nickel-allergy after deployment of such devices are uncommon but can be severe, resulting in dilemmas in the choice of treatment strategies and devices in managing nickel-sensitive patients with intracranial aneurysms...
April 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29684510/the-rodent-tibia-fracture-model-a-critical-review-and-comparison-with-the-complex-regional-pain-syndrome-literature
#12
REVIEW
Frank Birklein, Alaa Ibrahim, Tanja Schlereth, Wade S Kingery
Distal limb fracture is the most common cause of complex regional pain syndrome (CRPS), thus the rodent tibia fracture model (TFM) was developed to study CRPS pathogenesis. This comprehensive review summarizes the published TFM research and compares these experimental results with the CRPS literature. The TFM generated spontaneous and evoked pain behaviors, inflammatory symptoms (edema, warmth) and trophic changes (skin thickening, osteoporosis) resembling symptoms in early CRPS. Neuropeptides, inflammatory cytokines, and nerve growth factor (NGF) have been linked to pain behaviors, inflammation, and trophic changes in the TFM model and proliferating keratinocytes were identified as the primary source of cutaneous cytokines and NGF...
April 20, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29684403/white-matter-pathways-and-social-cognition
#13
REVIEW
Yin Wang, Athanasia Metoki, Kylie H Alm, Ingrid R Olson
There is a growing consensus that social cognition and behavior emerge from interactions across distributed regions of the "social brain". Researchers have traditionally focused their attention on functional response properties of these gray matter networks and neglected the vital role of white matter connections in establishing such networks and their functions. In this article, we conduct a comprehensive review of prior research on structural connectivity in social neuroscience and highlight the importance of this literature in clarifying brain mechanisms of social cognition...
April 20, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29684402/on-the-genesis-of-spatial-numerical-associations-evolutionary-and-cultural-factors-co-construct-the-mental-number-line
#14
REVIEW
Elizabeth Y Toomarian, Edward M Hubbard
Mapping numbers onto space is a common cognitive representation that has been explored in both behavioral and neuroimaging contexts. Empirical work probing the diverse nature of these spatial-numerical associations (SNAs) has led researchers to question 1) how the human brain links numbers with space, and 2) whether this link is biologically vs. culturally determined. We review the existing literature on the development of SNAs and situate that empirical work within cognitive and neuroscientific theoretical frameworks...
April 20, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29684307/osteochondroma-of-the-zygomatic-arch-a-case-report-and-review-of-the-literature
#15
R Patel, G Obeid
An osteochondroma, when reported in the maxillofacial region, is a benign neoplasm that involves the skull base, maxillary sinus, zygomatic arch, or mandible. Most commonly, the osteochondroma occurs in the coronoid process and the condyle. One rare subtype of osteochondroma reported in the literature, termed Jacob disease, arises from the coronoid process and interferes with the zygomatic arch. This report describes a unique case of an isolated osteochondroma arising from the zygomatic arch and interfering with the coronoid process, which was treated through surgical excision by an intraoral approach...
March 31, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29684250/electronic-medication-administration-records-in-long-term-care-facilities-a-scoping-review
#16
REVIEW
Andrew E C Fuller, Lisa M Guirguis, Cheryl A Sadowski, Mark J Makowsky
OBJECTIVES: To map the extent, range, and nature of research on the effectiveness, level of use, and perceptions about electronic medication administration records (eMARs) in long-term care facilities (LTCFs) and identify gaps in current knowledge and priority areas for future research. DESIGN: Scoping review of quantitative and qualitative literature. SETTING: Literature review. PARTICIPANTS: Original research relating to eMAR in LTCF was eligible for inclusion...
April 23, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29684249/standard-head-down-tilt-versus-modified-without-head-down-tilt-postural-drainage-in-infants-and-young-children-with-cystic-fibrosis
#17
REVIEW
Diana A Freitas, Gabriela Ss Chaves, Thayla A Santino, Cibele Td Ribeiro, Fernando Al Dias, Ricardo O Guerra, Karla Mpp Mendonça
BACKGROUND: Postural drainage is used primarily in infants with cystic fibrosis from diagnosis up to the moment when they are mature enough to actively participate in self-administered treatments. However, there is a risk of gastroesophageal reflux associated with this technique.This is an update of a review published in 2015. OBJECTIVES: To compare the effects of standard postural drainage (15º to 45º head-down tilt) with modified postural drainage (15º to 30º head-up tilt) with regard to gastroesophageal reflux in infants and young children up to six years old with cystic fibrosis in terms of safety and efficacy...
March 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29684233/secondary-prevention-strategies-for-nonmelanoma-skin-cancer
#18
REVIEW
Adriana T Lopez, Richard D Carvajal, Larisa Geskin
Skin cancer is the most commonly diagnosed cancer in the United States and has become a major public health problem that continues to grow. Despite numerous initiatives and increased public awareness of the dangers of skin cancer, the incidence of skin cancer continues to rise worldwide. This highlights the need for a critical review of existing skin cancer prevention strategies as a means to determine where targeted efforts may improve patient outcomes. In this article, we review the published literature and evaluate secondary prevention strategies for nonmelanoma skin cancer...
April 15, 2018: Oncology (Williston Park, NY)
https://www.readbyqxmd.com/read/29684218/what-is-the-evidence-for-a-role-for-diet-and-nutrition-in-osteoarthritis
#19
Sally Thomas, Heather Browne, Ali Mobasheri, Margaret P Rayman
As current treatment options in OA are very limited, OA patients would benefit greatly from some ability to self-manage their condition. Since diet may potentially affect OA, we reviewed the literature on the relationship between nutrition and OA risk or progression, aiming to provide guidance for clinicians. For overweight/obese patients, weight reduction, ideally incorporating exercise, is paramount. The association between metabolic syndrome, type-2 diabetes and OA risk or progression may partly explain the apparent benefit of dietary-lipid modification resulting from increased consumption of long-chain omega-3 fatty-acids from oily fish/fish oil supplements...
May 1, 2018: Rheumatology
https://www.readbyqxmd.com/read/29684135/on-the-usefulness-of-narratives-an-interdisciplinary-review-and-theoretical-model
#20
Victoria A Shaffer, Elizabeth S Focella, Andrew Hathaway, Laura D Scherer, Brian J Zikmund-Fisher
Background: How can we use stories from other people to promote better health experiences, improve judgments about health, and increase the quality of medical decisions without introducing bias, systematically persuading the listeners to change their attitudes, or altering behaviors in nonoptimal ways? More practically, should narratives be used in health education, promotion, or behavior change interventions? Method: In this article, we address these questions by conducting a narrative review of a diverse body of literature on narratives from several disciplines to gain a better understanding about what narratives do, including their role in communication, engagement, recall, persuasion, and health behavior change...
April 19, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
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