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https://www.readbyqxmd.com/read/28532839/dry-ice-is-a-reliable-substrate-for-the-distribution-of-frozen-mouse-spermatozoa-a-multi-centric-study
#1
Marcello Raspa, Mo Guan, Renata Paoletti, Lluis Montoliu, Abdel Ayadi, Susan Marschall, Martin Fray, Ferdinando Scavizzi
Disseminating mouse stocks as frozen materials offers both ethical and logistical advantages over live animal shipment, minimizing the welfare issues and avoiding some of the complex custom regulations that are associated with live animal transportation. Embryo freezing in liquid nitrogen (LN2) at -196 °C has traditionally been the method of choice for archiving mouse lines. However, spermatozoa freezing is emerging as a more convenient alternative due to the application of innovative cryopreservation and recovery protocols...
July 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28532066/design-and-characterization-of-a-novel-nickel-free-cobalt-base-alloy-for-intravascular-stents
#2
Qiang Wang, Yibin Ren, M Babar Shahzad, Wei Zhang, Xumeng Pan, Song Zhang, Dan Zhang
Co-Cr-W-Ni alloy (L605) with high tensile strength is used in coronary stents. The thickness of individual strut of the stent is reduced which can decrease the stent restenosis rate. However, about 10% Ni element content in L605 is found to cause allergic reactions and pulmonary embolism, similar to the traditional 316L stainless steel. In this study, a novel nickel-free cobalt-base alloy Co-20Cr-12Fe-18Mn-2Mo-4W-N (wt%) was designed and fabricated in order to efficiently avoid the potential hazards of Ni element...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28531798/environmental-hazard-assessment-of-a-marine-mine-tailings-deposit-site-and-potential-implications-for-deep-sea-mining
#3
Nélia C Mestre, Thiago L Rocha, Miquel Canals, Cátia Cardoso, Roberto Danovaro, Antonio Dell'Anno, Cristina Gambi, Francesco Regoli, Anna Sanchez-Vidal, Maria João Bebianno
Portmán Bay is a heavily contaminated area resulting from decades of metal mine tailings disposal, and is considered a suitable shallow-water analogue to investigate the potential ecotoxicological impact of deep-sea mining. Resuspension plumes were artificially created by removing the top layer of the mine tailings deposit by bottom trawling. Mussels were deployed at three sites: i) off the mine tailings deposit area; ii) on the mine tailings deposit beyond the influence from the resuspension plumes; iii) under the influence of the artificially generated resuspension plumes...
May 18, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28529146/multiple-endpoints-to-evaluate-pristine-and-remediated-titanium-dioxide-nanoparticles-genotoxicity-in-lung-epithelial-a549-cells
#4
Andrea Stoccoro, Sebastiano Di Bucchianico, Fabio Coppedè, Jessica Ponti, Chiara Uboldi, Magda Blosi, Camilla Delpivo, Simona Ortelli, Anna Luisa Costa, Lucia Migliore
Titanium dioxide nanoparticles (TiO2 NP) are broadly used in a wide range of applications. Several studies have reported that TiO2 NP possess cytotoxic and genotoxic properties that could induce adverse health effects in humans. The FP7 Sanowork project was aimed to minimize occupational hazard and exposure to engineered nanomaterials (ENM), including TiO2 NP, through the surface modification in order to avoid possible adverse toxic effects for humans. In this study we investigated cytotoxicity, genotoxicity and epigenetic properties of TiO2 NP uncoated and coated with silica or citrate, as well as of the benchmark material P25...
May 18, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28528420/soil-or-dust-for-health-risk-assessment-studies-in-urban-environment
#5
M Gabarrón, A Faz, J A Acosta
To identify the best material (soil or dust) to be selected for health-risk assessment studies, road dust and urban soil from three cities with different population densities were collected, and size fractions were analysed for metal content (Pb, Zn, Cu, Cd, Cr, Co, and Ni). Results showed similar distribution of the size particles among cities, predominating fractions between 75 and 2000 μm in road dust and particles below 75 μm in soil. Metals were mainly bound to PM10 in both soil and road dust increasing the risk of adverse health effects, overall through inhalation exposure...
May 20, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28525808/characterization-of-post-disaster-environmental-management-for-hazardous-materials-incidents-lessons-learnt-from-the-tianjin-warehouse-explosion-china
#6
Hui Zhang, Huabo Duan, Jian Zuo, MingWei Song, Yukui Zhang, Bo Yang, Yongning Niu
Hazardous Materials Incidents (HMIs) have attracted a growing public concern worldwide. The health risks and environmental implications associated with HMIs are almost invariably severe, and underscore the urgency for sound management. Hazardous Materials Explosion incidents (HMEIs) belong to a category of extremely serious HMIs. Existing studies placed focuses predominately on the promptness and efficiency of emergency responses to HMIs and HMEIs. By contrast, post-disaster environmental management has been largely overlooked...
May 16, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28521282/the-possibility-of-using-c20-fullerene-and-graphene-as-semiconductor-segments-for-detection-and-destruction-of-cyanogen-chloride-chemical-agent
#7
Parvaneh Pakravan, Seyyed Amir Siadati
Detection of hazardous chemical species by changing the electrical conductivity of a semiconductor matter is a proposed and applied way for decreasing their subsequent unpleasant effects. Recently, many examples of using inorganic or organic materials, polymeric, and also nano-sized species as sensors were reported in which, in some cases, those matters were strongly affective and suitable. In this project, we have made an assessment on whether the graphene segment or C20 fullerene, able to sense the existence of cyanogen chloride NCCl? In order to gain trustable results, the possible reaction pathways along with the adsorption kinetics were investigated...
April 27, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28521168/ecotoxicity-testing-and-environmental-risk-assessment-of-iron-nanomaterials-for-sub-surface-remediation-recommendations-from-the-fp7-project-nanorem
#8
Rune Hjorth, Claire Coutris, Nhung H A Nguyen, Alena Sevcu, Juliàn Alberto Gallego-Urrea, Anders Baun, Erik J Joner
Nanoremediation with iron (Fe) nanomaterials opens new doors for treating contaminated soil and groundwater, but is also accompanied by new potential risks as large quantities of engineered nanomaterials are introduced into the environment. In this study, we have assessed the ecotoxicity of four engineered Fe nanomaterials, specifically, Nano-Goethite, Trap-Ox Fe-zeolites, Carbo-Iron(®) and FerMEG12, developed within the European FP7 project NanoRem for sub-surface remediation towards a test battery consisting of eight ecotoxicity tests on bacteria (V...
May 13, 2017: Chemosphere
https://www.readbyqxmd.com/read/28520742/experimental-outgassing-of-toxic-chemicals-to-simulate-the-characteristics-of-hazards-tainting-globally-shipped-products
#9
Lygia Therese Budnik, Nadine Austel, Sabrina Gadau, Stefan Kloth, Jens Schubert, Harald Jungnickel, Andreas Luch
Ambient monitoring analyses may identify potential new public health hazards such as residual levels of fumigants and industrial chemicals off gassing from products and goods shipped globally. We analyzed container air with gas chromatography coupled to mass spectrometry (TD-2D-GC-MS/FPD) and assessed whether the concentration of the volatiles benzene and 1,2-dichloroethane exceeded recommended exposure limits (REL). Products were taken from transport containers and analyzed for outgassing of volatiles. Furthermore, experimental outgassing was performed on packaging materials and textiles, to simulate the hazards tainting from globally shipped goods...
2017: PloS One
https://www.readbyqxmd.com/read/28520711/inhalational-chlorine-injuries-at-public-aquatic-venues-california-2008-2015
#10
Jason A Wilken, Michele DiMaggio, Matthew Kaufmann, Kevin O'Connor, Svetlana Smorodinsky, Christina Armatas, Tracy Barreau, Richard Kreutzer, Lino Ancheta
In June 2015, personnel from California's Contra Costa Health Services Environmental Health and Hazardous Materials (hazmat) divisions were alerted to a possible chemical release at a swimming pool in an outdoor municipal water park. Approximately 50 bathers were in the pool when symptoms began; 34 (68%) experienced vomiting, coughing, or eye irritation. Among these persons, 17 (50%) were treated at the scene by Contra Costa's Emergency Medical Services (EMS) and released, and 17 (50%) were transported to local emergency departments; five patients also were evaluated later at an emergency department or by a primary medical provider...
May 19, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28520704/adverse-events-associated-with-treatment-of-multidrug-resistant-tuberculosis-in-china-an-ambispective-cohort-study
#11
Yang Zhang, Shanshan Wu, Yinyin Xia, Ni Wang, Lin Zhou, Jing Wang, Renfei Fang, Feng Sun, Mingting Chen, Siyan Zhan
BACKGROUND Adverse events are under-appreciated negative consequences that are significant clinical problems for patients undergoing anti-MDR-TB treatment due to longer duration of treatment and more need for concurrent use of multiple second-line drugs. The aim of this study was to determine the incidence of adverse events and their impact on MDR-TB therapy and treatment outcome, and to identify possible drug-event pairs in China. MATERIAL AND METHODS An ambispective cohort study was conducted based on hospital medical records, which included a retrospective study that enrolled 751 MDR-TB patients receiving standardized regimen between May 2009 and July 2013, and a follow-up investigation of treatment outcome conducted in December 2016 in China...
May 18, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28512176/extractables-screening-of-polypropylene-resins-used-in-pharmaceutical-packaging-for-safety-hazards
#12
Dennis Jenke
Pharmaceutical products are packaged in containers so that they can be manufactured, distributed and used. Because extractables from such containers are precursors of leachable impurities in the product, extractables represent potential hazards to user safety. Polypropylene resins are frequently used as materials of construction for packaging of liquid parenteral drug products. Thus extractables profiling of polypropylene resins may be an effective means of hazard identification associated with the resin's safe use...
May 15, 2017: PDA Journal of Pharmaceutical Science and Technology
https://www.readbyqxmd.com/read/28510321/novel-zns-carbon-nanofibers-photocatalyst-for-degradation-of-rhodamine-6g-kinetics-tracking-of-operational-parameters-and-development-of-a-kinetics-model
#13
Ali Mehrizad, Parvin Gharbani
A novel nanocomposite in the role of photocatalyst was prepared by composition of zinc sulfide (ZnS) nanoparticles with carbon nanofibers (CNFs) and was characterized. The XRD, EDX, and FE-SEM analysis revealed that ZnS is successfully embedded in CNFs matrix. The DRS results indicated that supporting of ZnS by CNFs led to a decrease of the band gap energy. The photocatalytic degradation of a hazardous xanthine dye, Rhodamine 6 G (Rh-6G), by the prepared ZnS/CNFs composite was examined from the kinetics point of view...
May 16, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28510305/reactive-precipitation-of-anhydrous-alkali-sulfide-nanocrystals-with-concomitant-abatement-of-hydrogen-sulfide-and-co-generation-of-hydrogen
#14
Yongan Yang, Xuemin Li, Yangzhi Zhao, Alice Brennan, Miranda McCeig, Colin A Wolden
Anhydrous alkali sulfide (M2S, M = Li and Na) nanocrystals (NCs) are important materials central to the development of next generation cathodes and solid state electrolytes for advanced batteries, but not commercially available at present. This work reports an innovative method to directly synthesize M2S-NCs through alcohol-mediated reactions between alkali metals and hydrogen sulfide (H2S). In the first step, the alkali metal is complexed with alcohol in solution, forming metal alkoxide (ROM) and releasing hydrogen (H2)...
May 16, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28504242/simultaneous-microfluidic-spinning-of-multiple-strands-of-submicron-fiber-for-the-production-of-free-standing-porous-membranes-for-biological-application
#15
DoYeun Park, JiSoo Park, Heeyeong Jang, Jie Cheng, Soo-Hyun Kim, Sang-Hoon Lee
Microfibers produced using electrospinning and microfluidics-based technologies have been developed as a powerful tool in tissue engineering applications such as drug delivery and scaffolds. The applications of these fibers, however, have been limited because of the hazardous solvents used to make them, difficulties in controlling the pore sizes of their membrane forms, and downscaling the size of the fiber. Nevertheless, extending the use of these fibers such as the production of a free-standing porous membrane appropriate for cell-based research is highly needed for tissue engineering, organ-on-a-chip, and drug delivery research and applications...
May 15, 2017: Biofabrication
https://www.readbyqxmd.com/read/28498135/removal-of-toxic-congo-red-dye-from-water-employing-low-cost-coconut-residual-fiber
#16
K C Rani, Aduja Naik, Ram Saran Chaurasiya, K S M S Raghavarao
The coconut residual fiber (CRF) is the major byproduct obtained during production of virgin coconut oil. Its application as a biosorbent for adsorption of Congo red was investigated. The CRF was subjected to different pretreatments, namely, pressure cooking, hexane treatment, acid treatment and their combinations. The pretreatment of CRF with the combination of hexane, acid, and pressure cooking resulted in the highest degree of adsorption. The equilibrium data were analyzed and found to fit best to both Langmuir and Freundlich isotherms...
May 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28494737/lipid-nanoparticles-as-potential-gene-therapeutic-delivery-systems-for-oral-administration
#17
Golnar Dorraj, Juan José Carreras, Hugo Núñez, Issam Abushammala, Ana Melero
Gene therapy has experimented an increasing attention in the last decades, due to its enormous potential applications in the medical field. It can be defined as the use of genes or genetic material (DNA, RNA, oligonucleotides) to treat or prevent a disease state, generally a genetic-based one. Other applications, like treating viral, bacterial or parasite infections or development of vaccines are gaining also interest. Efficient gene therapy is mainly dependent on the ability of the highly labile genetic material to reach the therapeutic target...
May 10, 2017: Current Gene Therapy
https://www.readbyqxmd.com/read/28494628/probabilistic-risk-assessment-of-emerging-materials-case-study-of-titanium-dioxide-nanoparticles
#18
Michael P Tsang, Danail Hristozov, Alex Zabeo, Antti Joonas Koivisto, Alexander Christian Østerskov Jensen, Keld Alstrup Jensen, Chengfang Pang, Antonio Marcomini, Guido Sonnemann
The development and use of emerging technologies such as nanomaterials can provide both benefits and risks to society. Emerging materials may promise to bring many technological advantages but may not be well-characterized in terms of their production volumes, magnitude of emissions, behavior in the environment and effects on living organisms. This uncertainty can present challenges to scientists developing these materials and persons responsible for defining and measuring their adverse impacts. Human health risk assessment is a method of identifying the intrinsic hazard of and quantifying the dose-response relationship and exposure to a chemical, to finally determine the estimation of risk...
May 12, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/28494363/reductive-solidification-stabilization-of-chromate-in-municipal-solid-waste-incineration-fly-ash-by-ascorbic-acid-and-blast-furnace-slag
#19
Xian Zhou, Min Zhou, Xian Wu, Yi Han, Junjun Geng, Teng Wang, Sha Wan, Haobo Hou
Fly ash is a hazardous byproduct of municipal solid waste incineration (MSWI). Cementitious material that is based on ground-granulated blast furnace slag (GGBFS) has been tested and proposed as a binder to stabilize Pb, Cd, and Zn in MSWI fly ash (FA). Cr, however, still easily leaches from MSWI FA. Different reagents, such as ascorbic acid (VC), NaAlO2, and trisodium salt nonahydrate, were investigated as potential Cr stabilizers. The results of the toxicity characteristic leaching procedure (TCLP) showed that VC significantly improved the stabilization of Cr via the reduction of Cr(VI) to Cr(III)...
April 21, 2017: Chemosphere
https://www.readbyqxmd.com/read/28494311/bromination-of-petroleum-coke-for-elemental-mercury-capture
#20
Yi Xiao, Deepak Pudasainee, Rajender Gupta, Zhenghe Xu, Yongfa Diao
Activated carbon injection has been proven to be an effective control technology of mercury emission from coal-fired power plants. Petroleum coke is a waste by-product of petroleum refining with large quantities readily available around the world. Due to its high inherent sulfur content, petroleum coke is an attractive raw material for developing mercury capture sorbent, converting a waste material to a value-added product of important environmental applications. In this study, petroleum coke was brominated by chemical-mechanical bromination...
April 18, 2017: Journal of Hazardous Materials
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