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https://www.readbyqxmd.com/read/28641397/myocardial-scar-location-as-detected-by-cardiac-magnetic-resonance-is-associated-with-the-outcome-in-heart-failure-patients-undergoing-surgical-ventricular-reconstruction
#1
Serenella Castelvecchio, Giulia Careri, Federico Ambrogi, Antonia Camporeale, Lorenzo Menicanti, Francesco Secchi, Massimo Lombardi
OBJECTIVES: Post-infarction myocardial scar causes adverse left ventricular remodelling and negatively affects the prognosis. We sought to investigate whether scar extent and location obtained by cardiac magnetic resonance may affect the reverse remodelling and survival of heart failure patients undergoing surgical ventricular reconstruction. METHODS: From January 2011 to December 2015, 151 consecutive patients with previous myocardial infarction and left ventricular remodelling underwent surgical ventricular reconstruction at our Institution, of which 88 (58%) patients had a preoperative protocol-standardized late gadolinium enhancement (LGE)-cardiac magnetic resonance examination during the week before surgery...
June 21, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28632490/the-florence-statement-on-triclosan-and-triclocarban
#2
Rolf U Halden, Avery E Lindeman, Allison E Aiello, David Andrews, William A Arnold, Patricia Fair, Rebecca E Fuoco, Laura A Geer, Paula I Johnson, Rainer Lohmann, Kristopher McNeill, Victoria P Sacks, Ted Schettler, Roland Weber, R Thomas Zoeller, Arlene Blum
The Florence Statement on Triclosan and Triclocarban documents a consensus of more than 200 scientists and medical professionals on the hazards of and lack of demonstrated benefit from common uses of triclosan and triclocarban. These chemicals may be used in thousands of personal care and consumer products as well as in building materials. Based on extensive peer-reviewed research, this statement concludes that triclosan and triclocarban are environmentally persistent endocrine disruptors that bioaccumulate in and are toxic to aquatic and other organisms...
June 20, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28628421/high-grade-serous-ovarian-cancer-associations-between-brca-mutation-status-ct-imaging-phenotypes-and-clinical-outcomes
#3
Stephanie Nougaret, Yulia Lakhman, Mithat Gönen, Debra A Goldman, Maura Miccò, Melvin D'Anastasi, Sarah A Johnson, Krishna Juluru, Angela G Arnold, Ramon E Sosa, Robert A Soslow, Hebert Alberto Vargas, Hedvig Hricak, Noah D Kauff, Evis Sala
Purpose To investigate the associations between BRCA mutation status and computed tomography (CT) phenotypes of high-grade serous ovarian cancer (HGSOC) and to evaluate CT indicators of cytoreductive outcome and survival in patients with BRCA-mutant HGSOC and those with BRCA wild-type HGSOC. Materials and Methods This HIPAA-compliant, institutional review board-approved retrospective study included 108 patients (33 with BRCA mutant and 75 with BRCA wild-type HGSOC) who underwent CT before primary debulking...
June 16, 2017: Radiology
https://www.readbyqxmd.com/read/28626847/injury-intense-dust-exposure-and-chronic-disease-among-survivors-of-the-world-trade-center-terrorist-attacks-of-september-11-2001
#4
Howard E Alper, Shengchao Yu, Steven D Stellman, Robert M Brackbill
BACKGROUND: The World Trade Center attack of September 11, 2001 in New York City (9/11) exposed thousands of people to intense concentrations of hazardous materials that have resulted in reports of increased levels of asthma, heart disease, diabetes, and other chronic diseases along with psychological illnesses such as post-traumatic stress disorder (PTSD). Few studies have discriminated between health consequences of immediate (short-term or acute) intense exposures versus chronic residential or workplace exposures...
December 2017: Injury Epidemiology
https://www.readbyqxmd.com/read/28626123/significance-of-intratracheal-instillation-tests-for-the-screening-of-pulmonary-toxicity-of-nanomaterials
#5
Yasuo Morimoto, Hiroto Izumi, Yukiko Yoshiura, Yuri Fujisawa, Katsuhide Fujita
Inhalation tests are the gold standard test for the estimation of the pulmonary toxicity of respirable materials. Intratracheal instillation tests have been used widely, but they yield limited evidence of the harmful effects of respirable materials. We reviewed the effectiveness of intratracheal instillation tests for estimating the hazards of nanomaterials, mainly using research papers featuring intratracheal instillation and inhalation tests centered on a Japanese national project. Compared to inhalation tests, intratracheal instillation tests induced more acute inflammatory responses in the animal lung due to a bolus effect regardless of the toxicity of the nanomaterials...
2017: Journal of UOEH
https://www.readbyqxmd.com/read/28623725/a-new-route-to-the-stable-capture-and-final-immobilization-of-radioactive-cesium
#6
Jae Hwan Yang, Ahreum Han, Joo Young Yoon, Hwan-Seo Park, Yung-Zun Cho
Radioactive Cs released from damaged fuel materials in the event of nuclear accidents must be controlled to prevent the spreading of hazardous Cs into the environment. This study describes a simple and novel process to safely manage Cs gas by capturing it within ceramic filters and converting it into monolithic waste forms. The results of Cs trapping tests showed that CsAlSiO4 was a reaction product of gas-solid reactions between Cs gas and our ceramic filters. Monolithic waste forms were readily prepared from the Cs-trapping filters by the addition of a glass frit followed by thermal treatment at 1000°C for 3h...
June 8, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28618276/common-explosives-tnt-rdx-hmx-and-their-fate-in-the-environment-emphasizing-bioremediation
#7
REVIEW
Soumya Chatterjee, Utsab Deb, Sibnarayan Datta, Clemens Walther, Dharmendra K Gupta
Explosive materials are energetic substances, when released into the environment, contaminate by posing toxic hazards to environment and biota. Throughout the world, soils are contaminated by such contaminants either due to manufacturing operations, military activities, conflicts of different levels, open burning/open detonation (OB/OD), dumping of munitions etc. Among different forms of chemical explosives, 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), and octahydro-1,3,5,7-tetranitro- 1,3,5,7-tetrazocine (HMX) are most common...
June 4, 2017: Chemosphere
https://www.readbyqxmd.com/read/28611349/stromal-expression-of-vimentin-predicts-the-clinical-outcome-of-stage-ii-colorectal-cancer-for-high-risk-patients
#8
Li-Guo Liu, Xue-Bing Yan, Ru-Ting Xie, Zhi-Ming Jin, Yi Yang
BACKGROUND Increased expression of vimentin in tissue samples from patients with colorectal cancer (CRC) has been previously demonstrated, but its prognostic significance remains controversial, and the clinical significance for patients with stage II CRC is still unknown. The aim of this study was to evaluate the expression of vimentin in CRC and its potential prognostic significance. MATERIAL AND METHODS We analyzed vimentin expression in 203 CRC tissue samples from patients with stage II cancer using immunohistochemistry, and correlated the findings with clinicopathological patient features...
June 14, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28609661/the-use-of-pesticides-in-belgian-illicit-indoor-cannabis-plantations
#9
Eva Cuypers, Wouter Vanhove, Joachim Gotink, Arne Bonneure, Patrick Van Damme, Jan Tytgat
Cannabis (Cannabis spp.) use and cultivation continue to increase in many (European) countries. The illicit indoor cannabis plantations that supply Belgian and European cannabis markets create problems and concerns about health and safety of intervention staff, dismantling companies, the direct environment of cannabis plantations and, eventually, of cannabis users. Main risks may come from pesticide residues on plants, cultivation infrastructure and materials; left-over plant growth-promoting substances; mycotoxins from fungal pathogens on harvested plants; and/or high levels of cannabinoids in cannabis plant parts for consumption...
May 25, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28609230/evaluating-polymer-degradation-with-complex-mixtures-using-a-simplified-surface-area-method
#10
Kandace M Steele, Todd Pelham, Robert N Phalen
Chemical resistant gloves, designed to protect workers from chemical hazards, are made from a variety of polymer materials such as plastic, rubber, and synthetic rubber. One material does not provide protection against all chemicals, thus proper polymer selection is critical. Standardized testing, such as chemical degradation tests, are used to aid in the selection process. The current methods of degradation ratings based on changes in weight or tensile properties can be expensive and data often do not exist for complex chemical mixtures...
June 13, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28605826/inhibition-of-hazardous-compound-formation-in-muscle-foods-by-antioxidative-phytophenols
#11
REVIEW
Youling L Xiong
Individual and mixed herbal extracts, as well as plant spices, are widely used in the preparation of muscle foods to enhance the organoleptic attributes. Abundantly rich in phenolic compounds, many of the phytochemical extracts have been shown to possess strong radical-scavenging and metal ion-binding properties and hence exert antioxidant activity in meat products. Because of their antiradical nature, phenolic acids and flavonoids, such as tea catechins, caffeic acid, chlorogenic acid, and mixed polyphenols derived from rosemary, licorice, and other herbal materials, are capable of inhibiting the formation of harmful secondary products from oxidized lipids and proteins...
June 12, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28604801/high-blood-levels-of-lead-in-children-aged-6-36-months-in-kathmandu-valley-nepal-a-cross-sectional-study-of-associated-factors
#12
Meghnath Dhimal, Khem Bahadur Karki, Krishna Kumar Aryal, Bimala Dhimal, Hari Datt Joshi, Sajan Puri, Achyut Raj Pandey, Purushotam Dhakal, Arun Kumar Sharma, Ganendra Bhakta Raya, Imran Ansari, David A Groneberg, Ruth Müller, Ulrich Kuch
Young children are at greatest risk of exposure to lead and its effects. Although lead is one of the most widely used elements with known health hazard, there is little data on the blood lead level (BLL) of children in the Kathmandu Valley. Thus, this study aimed to assess factors associated with high BLL in children who were 6-36 months of age and resided in the Kathmandu Valley. In this hospital-based cross-sectional study 6-36 month-old children visiting the Paediatrics Outpatient Department of Tribhuvan University Teaching Hospital, Patan Hospital, and Siddhi Memorial Hospital were enrolled...
2017: PloS One
https://www.readbyqxmd.com/read/28604767/correlation-between-airborne-manganese-concentration-at-the-workstations-in-the-iron-foundry-and-manganese-concentration-in-workers-blood
#13
Seyedtaghi Mirmohammadi, Yosef Moghaddasi, Jamshid Yazdani, Razyeh Yousefinejad, Yahya Esfandyari, Mohsen Gorgani, Manijeh Habibpour
BACKGROUND: Manganese (Mn) used as raw material for melting process in the ferrous foundry is considered as hazardous neurotoxic substance because it accumulates in the central nervous system and may cause neurological disorders. The furnace-men and melting department workers are potentially exposed to manganese particles or fume in the workplace. The objective of the research has been to investigate the sources and levels of manganese exposure in the foundry by correlation of blood-manganese (B-Mn) and air-manganese (air-Mn) measurement...
June 12, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28600989/anisotropic-spherical-hexagon-cube-silver-nanoparticle-embedded-magnetic-carbon-nanosphere-as-platform-for-designing-of-tramadol-imprinted-polymer
#14
Santanu Patra, Ekta Roy, Retwik Parui, Rashmi Madhuri, Prashant K Sharma
Shape specific nanoparticles are getting a tremendous research interests due to their change in property with the shape. As far our knowledge, the impact of change in the shape of nanoparticle used as platform during synthesis of molecularly imprinted polymers (MIPs) has not been reported or tried. Herein, we have studied the effect of shape of silver nanoparticles (AgNPs) on the performance of MIPs. For this, different shaped (spherical, hexagon and cube) AgNPs were prepared by green-synthesis approach, modified with vinyl group, embedded into the shell of magnetic carbon nanoparticles and used as one of the functional monomer during tramadol imprinted polymer synthesis...
June 7, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28600872/anatomy-of-a-decision-ii-potential-effects-of-changes-to-tier-i-chemical-approaches-in-canadian-disposal-at-sea-program-sediment-assessment-protocols
#15
Sabine E Apitz, Suzanne Agius
The effects of possible changes to the Canadian two tiered assessment framework for dredged material based on outcomes of the 2006 Contaminated Dredged Material Management Decisions Workshop (CDMMD) are evaluated. Expanding on the "data mining" approach described in Apitz and Agius, 2013, which focused solely on chemical lines of evidence, the efficacy of Tier 1 approaches (increases to the number of chemical analytes, use of mean hazard quotients and the use of a screening bioassay) in predicting toxicity are evaluated...
June 10, 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/28599159/biosorption-of-metal-elements-by-exopolymer-nanofibrils-excreted-from-leptothrix-cells
#16
Tatsuki Kunoh, Makoto Nakanishi, Yoshihiro Kusano, Atsushi Itadani, Kota Ando, Syuji Matsumoto, Katsunori Tamura, Hitoshi Kunoh, Jun Takada
Leptothrix species, aquatic Fe-oxidizing bacteria, excrete nano-scaled exopolymer fibrils. Once excreted, the fibrils weave together and coalesce to form extracellular, microtubular, immature sheaths encasing catenulate cells of Leptothrix. The immature sheaths, composed of aggregated nanofibrils with a homogeneous-looking matrix, attract and bind aqueous-phase inorganics, especially Fe, P, and Si, to form seemingly solid, mature sheaths of a hybrid organic-inorganic nature. To verify our assumption that the organic skeleton of the sheaths might sorb a broad range of other metallic and nonmetallic elements, we examined the sorption potential of chemically and enzymatically prepared protein-free organic sheath remnants for 47 available elements...
May 4, 2017: Water Research
https://www.readbyqxmd.com/read/28595966/characterization-of-pkac%C3%AE-enzyme-kinetics-and-inhibition-in-an-hplc-assay-with-a-chromophoric-substrate
#17
Nicole M Luzi, Charles E Lyons, Darrell L Peterson, Keith C Ellis
Here we describe a convenient, inexpensive, and non-hazardous method for the measurement of the kinase activity of the catalytic subunit of cAMP-dependent protein kinase (PKACα). The assay is based on the separation of a substrate peptide labeled with a strong chromophore from the phosphorylated product peptide by high-performance liquid chromatograph (HPLC) and quantification of the product ratiometrically at a wavelength in the visual spectrum (Vis). The utility and reliability of the HPLC-Vis assay were demonstrated by characterizing the kinetic parameters (KM, Vmax) of the new Rh-MAB-Kemptide substrate, a commercially prepared TAMRA-Kemptide substrate, and ATP as well as the potency (IC50, Ki) of the known PKACα inhibitors H89 and PKI(5-24)...
June 5, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/28595804/techno-economic-feasibility-of-waste-biorefinery-using-slaughtering-waste-streams-as-starting-material-for-biopolyester-production
#18
Khurram Shahzad, Michael Narodoslawsky, Muhammad Sagir, Nadeem Ali, Shahid Ali, Muhammad Imtiaz Rashid, Iqbal Mohammad Ibrahim Ismail, Martin Koller
The utilization of industrial waste streams as input materials for bio-mediated production processes constitutes a current R&D objective not only to reduce process costs at the input side but in parallel, to minimize hazardous environmental emissions. In this context, the EU-funded project ANIMPOL elaborated a process for the production of polyhydroxyalkanoate (PHA) biopolymers starting from diverse waste streams of the animal processing industry. This article provides a detailed economic analysis of PHA production from this waste biorefinery concept, encompassing the utilization of low-quality biodiesel, offal material and meat and bone meal (MBM)...
June 5, 2017: Waste Management
https://www.readbyqxmd.com/read/28595153/preparation-and-characteristics-of-graphene-oxide-blending-pvdf-nanohybrid-membranes-and-their-applications-for-hazardous-dye-adsorption-and-rejection
#19
Zhenya Zhu, Lei Wang, Yawei Xu, Qingqing Li, Jialiang Jiang, Xudong Wang
Graphene oxide (GO) and lithium chloride (LiCl) were introduced into poly (vinylidene fluoride) (PVDF) membranes prepared using the immersion precipitation technique. The hydrophilicity, water flux, X-ray diffraction (XRD), zeta potential, SEM and AFM images of membranes were investigated. By adjusting the content of GO from 0wt% to 0.9 wt%, the water flux of PVDF/GO/LiCl nanohybrid membranes varied from 48.4L/m(2)h to 61.90L/m(2)h at 100kPa. Because of the synergistic effects of GO and LiCl particles, the surface free energy (|ΔGs|) of M3 (0...
May 23, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28593069/reproductive-toxic-chemicals-at-work-and-efforts-to-protect-workers-health-a-literature-review
#20
REVIEW
Kyung-Taek Rim
A huge number of chemicals are produced and used in the world, and some of them can have negative effects on the reproductive health of workers. To date, most chemicals and work environments have not been studied for their potential to have damaging effects on the workers' reproductive system. Because of the lack of information, many workers may not be aware that such problems can be related to occupational exposures. Newly industrialized countries such as Republic of Korea have rapidly amassed chemicals and other toxicants that pose health hazards, especially to the reproductive systems of workers...
June 2017: Safety and Health At Work
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