keyword
MENU ▼
Read by QxMD icon Read
search

WHI

keyword
https://www.readbyqxmd.com/read/28428186/features-of-alcohol-harm-reduction-advertisements-that-most-motivate-reduced-drinking-among-adults-an-advertisement-response-study
#1
Melanie A Wakefield, Emily Brennan, Kimberley Dunstone, Sarah J Durkin, Helen G Dixon, Simone Pettigrew, Michael D Slater
OBJECTIVES: To improve the effectiveness of alcohol harm reduction mass media campaigns, this study aimed to (1) identify existing advertisements (ads) with greatest potential to motivate reduced alcohol consumption, (2) assess consistency across audience subgroups in ad effectiveness and (3) identify ad features associated with effectiveness. DESIGN: Cross-sectional online ad response study with random assignment to view ads. PARTICIPANTS: 2174 Australian adult weekly drinkers recruited from an online panel...
April 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28421722/second-primary-cancer-risk-among-kidney-cancer-patients-in-korea-a-population-based-cohort-study
#2
Jae Young Joung, Whi-An Kwon, Jiwon Lim, Chang-Mo Oh, Kyu-Won Jung, Sung Han Kim, Ho Kyung Seo, Weon Seo Park, Jinsoo Chung, Kang Hyun Lee, Young-Joo Won
Purpose: Secondary primary cancers (SPCs) commonly arise in patients with renal cell carcinoma (RCC). We designed the present study to estimate the SPC incidence in Korean patients with RCC. Materials and Methods: The study cohort was population-based and consisted of 40,347 individuals from the Korean Central Cancer Registry who were diagnosed with primary renal cancer between 1993 and 2013. Standardized incidence ratios (SIRs) for SPCs were estimated for different ages at diagnosis, latencies, diagnostic periods, and treatments...
April 19, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28417334/sleep-quality-duration-and-breast-cancer-aggressiveness
#3
Allison Soucise, Caila Vaughn, Cheryl L Thompson, Amy E Millen, Jo L Freudenheim, Jean Wactawski-Wende, Amanda I Phipps, Lauren Hale, Lihong Qi, Heather M Ochs-Balcom
PURPOSE: Epidemiological studies suggest that short sleep duration and poor sleep quality may increase breast cancer risk. However, whether sleep is associated with breast tumor aggressiveness characteristics has largely been unexplored. METHODS: The study included 4171 non-Hispanic whites (NHW) and 235 African Americans (AA) diagnosed with incident, primary, invasive breast cancer in the Women's Health Initiative (WHI) Observational Study (1994-2013). We used logistic regression to examine the association of baseline sleep (sleep duration, sleep quality, WHI Insomnia Rating Scale) with tumor grade, stage, hormone receptor status, HER2 status...
April 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28401055/effect-of-the-baseline-vitamin-d-level-on-growth-outcome-in-pediatric-crohn-disease
#4
Eun Joo Lee, Jin Soo Moon, Jae Sung Ko, Hye Ran Yang, Ju Young Jang, Ju Whi Kim, Kyung Jae Lee
PURPOSE: Vitamin D deficiency is common in Crohn disease (CD). The aim of the study was to examine the prevalence of vitamin D deficiency and evaluate the association between vitamin D status and growth outcome in Korean pediatric CD patients. METHODS: In this retrospective study, 17 children younger than 18 years old diagnosed with CD were enrolled and their serum 25-hydroxy vitamin D (25[OH]D) was checked between 2011 and 2015. We categorized the patients into two groups, Group 1 and Group 2...
March 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/28393764/highly-luminescent-silica-coated-cds-cdse-cds-nanoparticles-with-strong-chemical-robustness-and-excellent-thermal-stability
#5
Nianfang Wang, Sungjun Koh, Byeong Guk Jeong, Dongkyu Lee, Whi Dong Kim, Kyoungwon Park, Min Ki Nam, Kangha Lee, Yewon Kim, Baek-Hee Lee, Kangtaek Lee, Wan Ki Bae, Doh C Lee
We present facile synthesis of bright CdS/CdSe/CdS@SiO2 nanoparticles with 72% of quantum yields (QYs) retaining ca 80% of the original QYs. The main innovative point is the utilization of the highly luminescent CdS/CdSe/CdS seed/spherical quantum well/shell (SQW) as silica coating seeds. The significance of inorganic semiconductor shell passivation and structure design of quantum dots (QDs) for obtaining bright QD@SiO2 is demonstrated by applying silica encapsulation via reverse microemulsion method to three kinds of QDs with different structure: CdSe core and 2 nm CdS shell (CdSe/CdS-thin); CdSe core and 6 nm CdS shell (CdSe/CdS-thick); and CdS core, CdSe intermediate shell and 5 nm CdS outer shell (CdS/CdSe/CdS-SQW)...
May 5, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28366425/osteoporosis-in-the-women-s-health-initiative-another-treatment-gap
#6
Maryam Sattari, Jane A Cauley, Cynthia Garvan, Karen C Johnson, Michael J LaMonte, Wenjun Li, Marian Limacher, Todd Manini, Gloria E Sarto, Shannon D Sullivan, Jean Wactawski-Wende, Rebecca J Beyth
BACKGROUND: Osteoporotic fractures are associated with high morbidity, mortality, and cost. METHODS: We performed a post hoc analysis of the Women's Health Initiative (WHI) clinical trials (CT) data to assess osteoporosis treatment and identify participant characteristics associated with utilization of osteoporosis medication(s) after new diagnoses of osteoporosis and/or fracture. Information from visits prior to and immediately subsequent to the first fracture event or osteoporosis diagnosis were evaluated for medication use...
March 30, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28341621/cancer-cachexia-induced-muscle-atrophy-evidence-for-alterations-in-micrornas-important-for-muscle-size
#7
David Edward Lee, Jacob L Brown, Megan E Rosa-Caldwell, Thomas A Blackwell, Richard A Perry, Lemuel A Brown, Bhuwan Khatri, Dongwon Seo, Walter Gay Bottje, Tyrone Anthony Washington, Michael P Wiggs, Byung-Whi Kong, Nicholas Perry Greene
Muscle atrophy is a hallmark of cancer cachexia resulting in impaired function and quality of life and cachexia is the immediate cause of death for 20-40% of cancer patients. Multiple microRNAs (miRNAs) have been identified as being involved in muscle development and atrophy, however less is known specifically on miRNAs in cancer cachexia. PURPOSE: The purpose of this investigation was to examine the miRNA profile of skeletal muscle atrophy induced by cancer cachexia to uncover potential miRNAs involved with this catabolic condition...
March 24, 2017: Physiological Genomics
https://www.readbyqxmd.com/read/28338878/risk-of-diabetes-after-hysterectomy-with-or-without-oophorectomy-in-postmenopausal-women
#8
Juhua Luo, JoAnn E Manson, Rachel Peragallo Urrutia, Michael Hendryx, Erin S LeBlanc, Karen L Margolis
The aim of this study was to determine the associations between hysterectomy, bilateral salpingo-oophorectomy (BSO), and incidence of diabetes in postmenopausal women participating in the Women's Health Initiative (WHI), a series of trials conducted in the United States, during the period 1993-1998. A total of 67,130 postmenopausal women aged 50-79 years were followed for a mean of 13.4 years. Among them, 7,430 cases of diabetes were diagnosed. Multivariable Cox proportional hazards models were used to assess the association between hysterectomy/oophorectomy status and diabetes incidence...
March 6, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28333333/why-aren-t-women-choosing-stem-academic-jobs-observations-from-a-small-group-discussion-at-the-2016-american-society-for-microbiology-annual-meeting
#9
Elizabeth M Adamowicz
This commentary summarizes a small-group discussion that recently occurred at the American Society for Microbiology annual general meeting, ASM Microbe, in Boston, Massachusetts, on 16-20 June 2016, on the topic 'why are so few women choosing to become academics?' Specifically, the discussion focused on asking what the actual and perceived barriers to academic STEM careers women face, and possible solutions to address them which would make women more likely to seek out academic careers. The conclusions reached suggest that, despite improvement in recent years, women and minorities still face complex barriers to STEM academic careers, and further research is needed to determine the best solutions to this problem...
March 1, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28330982/response-to-why-medical-professionals-have-no-moral-claim-to-conscientious-objection-accommodation-in-liberal-democracies-by-schuklenk-and-smalling
#10
Richard John Lyus
Bioethicists commenting on conscientious objection and abortion should consider the empirical data on abortion providers. Abortion providers do not fall neatly into groups of providers and objectors, and ambivalence is a key theme in their experience. Practical details of abortion services further upset the dichotomy. These empirical facts are important because they demonstrate that the way the issue is described in analytical bioethics does not reflect reality. Addressing conscientious objection as a barrier to patient access requires engaging with those who provide the service and those who are able to but do not...
April 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28324031/sex-steroid-hormones-and-fracture-in-a-multi-ethnic-cohort-of-women-the-women-s-health-initiative-study-whi
#11
Jane A Cauley, Michelle E Danielson, Guru Rajesh Jammy, Doug C Bauer, Rebecca Jackson, Jean Wactawski-Wende, Rowan T Chlebowski, Kristine E Ensrud, Robert Boudreau
CONTEXT: We hypothesize that endogenous sex steroids are associated with fracture risk independent of race/ethnicity. DESIGN AND SETTING: We performed a nested case-control study within the prospective Women's Health Initiative Observational Study (WHI-OS). Incident non-spine fractures were identified in 381 Black, 192 Hispanic, 112 Asian, and 46 Native American women over an average of 8.6 years. A random sample of 400 White women who experienced an incident fracture was chosen...
January 25, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28281363/the-evidence-base-for-hrt-what-can-we-believe
#12
REVIEW
R D Langer
Prior to the unexpected early termination of the Women's Health Initiative (WHI) trial of continuous conjugated equine estrogens (CEE) and medroxyprogesterone acetate (MPA), the prevailing view was that hormone replacement therapy (HRT) was a low-risk intervention with immediate value for symptom relief in recently menopausal women, and that it probably conferred long-term protection against the major chronic diseases that affect women after menopause. Rather than replicating prior studies, the WHI was designed to test whether the beneficial associations consistently seen in women starting HRT near menopause would be found in women well beyond menopause...
April 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28271007/terahertz-imaging-of-metastatic-lymph-nodes-using-spectroscopic-integration-technique
#13
Jae Yeon Park, Hyuck Jae Choi, Hwayeong Cheon, Seong Whi Cho, Seungkoo Lee, Joo-Hiuk Son
Terahertz (THz) imaging was used to differentiate the metastatic states of frozen lymph nodes (LNs) by using spectroscopic integration technique (SIT). The metastatic states were classified into three groups: healthy LNs, completely metastatic LNs, and partially metastatic LNs, which were obtained from three mice without infection and six mice infected with murine melanoma cells for 30 days and 15 days, respectively. Under histological examination, the healthy LNs and completely metastatic LNs were found to have a homogeneous cellular structure but the partially metastatic LNs had interfaces of the melanoma and healthy tissue...
February 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28254175/relationship-between-physical-activity-body-mass-index-and-risk-of-heart-failure
#14
Ambarish Pandey, Michael LaMonte, Liviu Klein, Colby Ayers, Bruce M Psaty, Charles B Eaton, Norrina B Allen, James A de Lemos, Mercedes Carnethon, Philip Greenland, Jarett D Berry
BACKGROUND: Lower leisure-time physical activity (LTPA) and higher body mass index (BMI) are independently associated with risk of heart failure (HF). However, it is unclear if this relationship is consistent for both heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF). OBJECTIVES: This study sought to quantify dose-response associations between LTPA, BMI, and the risk of different HF subtypes. METHODS: Individual-level data from 3 cohort studies (WHI [Women's Health Initiative], MESA [Multi-Ethnic Study of Atherosclerosis], and CHS [Cardiovascular Health Study]) were pooled and participants were stratified into guideline-recommended categories of LTPA and BMI...
March 7, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28244293/epidemiology-of-biliary-atresia-in-korea
#15
Kyung Jae Lee, Ju Whi Kim, Jin Soo Moon, Jae Sung Ko
Biliary atresia (BA) is the major cause of cholestasis and the leading indication for liver transplantation (LT). However, the incidence of BA in Korea has not been reported. The aim of this study was to investigate the incidence and clinical outcomes of BA in Korea. We used the Korean universal health insurance database and extracted data regarding BA patients younger than 18 years of age admitted between 2011 and 2015. The incidence of BA was calculated by dividing the number of BA patients by the number of live births...
April 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28235404/progesterone-signalling-in-broiler-skeletal-muscle-is-associated-with-divergent-feed-efficiency
#16
Walter Bottje, Byung-Whi Kong, Antonio Reverter, Ashley J Waardenberg, Kentu Lassiter, Nicholas J Hudson
BACKGROUND: We contrast the pectoralis muscle transcriptomes of broilers selected from within a single genetic line expressing divergent feed efficiency (FE) in an effort to improve our understanding of the mechanistic basis of FE. RESULTS: Application of a virtual muscle model to gene expression data pointed to a coordinated reduction in slow twitch muscle isoforms of the contractile apparatus (MYH15, TPM3, MYOZ2, TNNI1, MYL2, MYOM3, CSRP3, TNNT2), consistent with diminishment in associated slow machinery (myoglobin and phospholamban) in the high FE animals...
February 24, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/28231077/association-of-genetic-variation-in-the-tachykinin-receptor-3-locus-with-hot-flashes-and-night-sweats-in-the-women-s-health-initiative-study
#17
Carolyn J Crandall, JoAnn E Manson, Chancellor Hohensee, Steve Horvath, Jean Wactawski-Wende, Erin S LeBlanc, Mara Z Vitolins, Rami Nassir, Janet S Sinsheimer
OBJECTIVE: Vasomotor symptoms (VMS, ie, hot flashes or night sweats) are reported by many, but not all, women. The extent to which VMS are genetically determined is unknown. We evaluated the relationship of genetic variation and VMS. METHODS: In this observational study, we accessed data from three genome-wide association studies (GWAS) (SNP Health Association Resource cohort [SHARe], WHI Memory Study cohort [WHIMS+], and Genome-Wide Association Studies of Treatment Response in Randomized Clinical Trials [GARNET] studies, total n = 17,695) of European American, African American, and Hispanic American postmenopausal women aged 50 to 79 years at baseline in the Women's Health Initiative Study...
March 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28229477/-why-not-you-discourses-of-widening-access-on-uk-medical-school-websites
#18
Kirsty Alexander, Tania Fahey Palma, Sandra Nicholson, Jennifer Cleland
CONTEXT: In the UK, applications to medicine from those in lower socio-economic groups remain low despite significant investments of time, interest and resources in widening access (WA) to medicine. This suggests that medical schools' core messages about WA may be working to embed or further reinforce marginalisation, rather than to combat this. Our objective was to investigate how the value of WA is communicated by UK medical schools through their websites, and how this may create expectations regarding who is 'suitable' for medicine...
February 22, 2017: Medical Education
https://www.readbyqxmd.com/read/28229456/body-mass-index-waist-circumference-and-mortality-in-a-large-multiethnic-postmenopausal-cohort-results-from-the-women-s-health-initiative
#19
Zhao Chen, Yann C Klimentidis, Jennifer W Bea, Kacey C Ernst, Chengcheng Hu, Rebecca Jackson, Cynthia A Thomson
OBJECTIVES: To determine whether the relationship between anthropometric measurements of obesity and mortality varies according to age, race, and ethnicity in older women. DESIGN: Prospective cohort study of multiethnic postmenopausal women. SETTING: Women's Health Initiative (WHI) observational study and clinical trials in 40 clinics. PARTICIPANTS: Postmenopausal women aged 50-79 participating in WHI (N = 161,808). MEASUREMENTS: Baseline height, weight, and waist circumference (WC) were measured, and body mass index (BMI) was calculated based on height and weight...
February 23, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28194642/are-optimism-and-cynical-hostility-associated-with-smoking-cessation-in-older-women
#20
Ana M Progovac, Yue-Fang Chang, Chung-Chou H Chang, Karen A Matthews, Julie M Donohue, Michael F Scheier, Elizabeth B Habermann, Lewis H Kuller, Joseph S Goveas, Benjamin P Chapman, Paul R Duberstein, Catherine R Messina, Kathryn E Weaver, Nazmus Saquib, Robert B Wallace, Robert C Kaplan, Darren Calhoun, J Carson Smith, Hilary A Tindle
BACKGROUND: Optimism and cynical hostility independently predict morbidity and mortality in Women's Health Initiative (WHI) participants and are associated with current smoking. However, their association with smoking cessation in older women is unknown. PURPOSE: The purpose of this study is to test whether optimism (positive future expectations) or cynical hostility (mistrust of others) predicts smoking cessation in older women. METHODS: Self-reported smoking status was assessed at years 1, 3, and 6 after study entry for WHI baseline smokers who were not missing optimism or cynical hostility scores (n = 10,242)...
February 13, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
keyword
keyword
64994
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"