keyword
MENU ▼
Read by QxMD icon Read
search

WHI

keyword
https://www.readbyqxmd.com/read/29774271/gatekeepers-for-infertility-treatment-views-of-art-providers-concerning-referrals-by-non-art-providers
#1
Robert Klitzman
Many patients who might benefit from treatment using assisted reproductive technology (ART) do not receive it, raising critical questions of why, and how best to overcome existing barriers. In-depth interviews of approximately 1 h each were conducted with 27 ART providers (17 physicians and 10 other healthcare providers). These interviewees suggest that non-ART providers may serve as gatekeepers in a complex system, involving not only individual-level, but also dyadic and institutional, processes and factors related to provider-patient relationships...
April 2018: Reproductive Biomedicine & Society Online
https://www.readbyqxmd.com/read/29772926/caring-for-children-24-7-the-experience-of-wellchild-nurses-and-the-families-for-whom-they-are-providing-care-and-support
#2
Mark Whiting
There is a growing population of children with complex health needs and disabilities who are being cared for at home by their parents 24 hours per day, 7 days per week. Community Children's Nursing Teams are a major source of support to these children. In 2006, the charity WellChild introduced the first WellChild Nurse (WCN) post specifically focused upon this group of children. In order to gain insight into how the WCN model was supporting this group of children throughout the 24-hour day, semi-structured interviews were undertaken with 12 WCNs and 10 parents of children with a range of long-term clinical care needs...
January 1, 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29763969/hormone-replacement-therapy-for-women-previously-treated-for-endometrial-cancer
#3
REVIEW
Katharine A Edey, Stuart Rundle, Martha Hickey
BACKGROUND: Endometrial cancer is the sixth most common cancer in women worldwide and most commonly occurs after the menopause (75%) (globocan.iarc.fr). About 319,000 new cases were diagnosed worldwide in 2012. Endometrial cancer is commonly considered as a potentially 'curable cancer,' as approximately 75% of cases are diagnosed before disease has spread outside the uterus (FIGO (International Federation of Gynecology and Obstetrics) stage I). The overall five-year survival for all stages is about 86%, and, if the cancer is confined to the uterus, the five-year survival rate may increase to 97%...
May 15, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29762199/physical-activity-modifies-genetic-susceptibility-to-obesity-in-postmenopausal-women
#4
Heather M Ochs-Balcom, Leah Preus, Jing Nie, Jean Wactawski-Wende, Linda Agyemang, Marian L Neuhouser, Lesley Tinker, Cheng Zheng, Rasa Kazlauskaite, Lihong Qi, Lara E Sucheston-Campbell
OBJECTIVE: We conducted a gene-environment interaction study to evaluate whether the association of body mass index (BMI) associated meta genome-wide association study single-nucleotide polymorphisms (SNPs) (as a genetic risk score) and BMI is modified by physical activity and age. METHODS: In 8,206 women of European ancestry from the Women's Health Initiative (WHI), we used linear regression to examine main effects of the 95 SNP BMI genetic risk score (GRS) and physical activity on BMI, and evaluated whether genetic associations are modified by physical activity (two-way interaction) and age (three-way interaction)...
May 14, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29761014/strain-specific-differential-expression-of-astrocytes-and-microglia-in-the-mouse-hippocampus
#5
Jong Whi Kim, Sung Min Nam, Dae Young Yoo, Hyo Young Jung, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoon
Introduction: Genetic background influences neurotransmitter expression and function of the hippocampus. Genetic background influences the phenotype of the hippocampus, but expression of neuroglia in hippocampus has not been well established dependent on various mouse strains. Objectives: In this study, we investigated the effects of genetic background on cell population of astrocytes and microglia in eight widely used inbred strains (C57BL/6J, A/J, BALB/c, C3H/HeJ, FVB, 129/SvJ, DBA/1, and DBA/2) and one outbred strain (ICR)...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29751750/prevalence-and-risk-factors-of-elevated-alanine-aminotransferase-among-korean-adolescents-2001-2014
#6
Ju Whi Kim, Kyung Jae Lee, Hye Ran Yang, Ju Young Chang, Jin Soo Moon, Young-Ho Khang, Jae Sung Ko
BACKGROUND: An elevated alanine aminotransferase (ALT) level is a surrogate marker of non-alcoholic fatty liver disease (NAFLD), the most common liver disorder in adolescents. The majority of previous NAFLD studies in adolescents were performed in selected obese populations or had a cross-sectional design without a time-trend analysis. The purpose of this study was to estimate the prevalence and time trends of elevated ALT levels in a general adolescent population and to identify factors associated with ALT elevation...
May 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29738414/estrogen-alone-therapy-and-invasive-breast-cancer-incidence-by-dose-formulation-and-route-of-delivery-findings-from-the-whi-observational-study
#7
Chrisandra Shufelt, C Noel Bairey Merz, Mary B Pettinger, Lydia Choi, Rowan Chlebowski, Carolyn J Crandall, Simin Liu, Dorothy Lane, Ross Prentice, JoAnn E Manson
OBJECTIVE: Research on the relationships between different hormone therapy doses, formulation and routes of delivery, and subsequent breast cancer incidence has been limited. This study directly compared different estrogen doses, formulations, and route of delivery of estrogen alone among women with a hysterectomy in relation to invasive breast cancer incidence. METHODS: The Women's Health Initiative Observational Study is a large multicenter prospective cohort study conducted at 40 US sites...
May 7, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29716899/risk-factor-burden-heart-failure-and-survival-in-women-of-different-ethnic-groups-insights-from-the-women-s-health-initiative
#8
Khadijah Breathett, Iris Leng, Randi E Foraker, William T Abraham, Laura Coker, Keith E Whitfield, Sally Shumaker, JoAnn E Manson, Charles B Eaton, Barbara V Howard, Nkechinyere Ijioma, Crystal W Cené, Lisa W Martin, Karen C Johnson, Liviu Klein
BACKGROUND: The higher risk of heart failure (HF) in African-American and Hispanic women compared with white women is related to the higher burden of risk factors (RFs) in minorities. However, it is unclear if there are differences in the association between the number of RFs for HF and the risk of development of HF and death within racial/ethnic groups. METHODS AND RESULTS: In the WHI (Women's Health Initiative; 1993-2010), African-American (n=11 996), white (n=18 479), and Hispanic (n=5096) women with 1, 2, or 3+ baseline RFs were compared with women with 0 RF within their respective racial/ethnic groups to assess risk of developing HF or all-cause mortality before and after HF, using survival analyses...
May 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29693946/a-case-of-sudden-shock-during-caesarean-section-in-whi-ch-amniotic-fluid-embolism-is-suspected
#9
Hiroo Shimono, Satoko Haraguchi, Yuko Minoda, Mari Beppu, Naomi Shinmura, Yuki Suzuki, Mikiko Higashi, Yuichi Kanmura
We report a case of sudden shock during caesarean section under combined spinal epidural anesthesia. The patient was a 29-year-old woman. During the operation vital signs had been almost stable until a female-baby was born. But after the delivery of the placenta, the patient developed an episode of coughing and dyspnea followed by unconsciousness and bradycardia. She was given adrenaline and intubated, appearing ventricular fibrillation on a EKG. Cardiopulmonary resuscitation was immediately started and sinus rhythm returned...
May 2017: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/29681054/factors-that-predict-neutropenia-in-korean-patients-with-advanced-urothelial-cancer-after-cisplatin-based-systemic-chemotherapy
#10
Whi-An Kwon, Tae Hoon Oh, Jea Whan Lee, Ill Young Seo, Seung Chol Park
PURPOSE: The aim of this study was to identify factors that can be used to predict severe neutropenia (grade 3 or higher) in patients with advanced urothelial cancer after cisplatin-based systemic chemotherapy. MATERIALS AND METHODS: The study examined 79 Korean patients with advanced urothelial cancer who were treated with several cycles of cisplatin-based systemic chemotherapy from May 2006 to May 2015. Risk factors for neutropenia (grade 3 or higher) and for the occurrence of neutropenia (grade 3 or higher) during the first cycle of chemotherapy were examined...
April 19, 2018: Urology Journal
https://www.readbyqxmd.com/read/29680852/possible-association-between-obesity-and-periodontitis-in-patients-with-down-syndrome
#11
E Culebras-Atienza, F-J Silvestre, J Silvestre-Rangil
BACKGROUND: The present study was carried out to evaluate the possible association between obesity and periodontitis in patients with DS, and to explore which measure of obesity is most closely correlated to periodontitis. MATERIAL AND METHODS: A prospective observational study was made to determine whether obesity is related to periodontal disease in patients with DS. The anthropometric variables were body height and weight, which were used to calculate BMI and stratify the patients into three categories: < 25(normal weight), 25-29...
April 22, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29644766/fear-of-recurrence-among-older-breast-ovarian-endometrial-and-colorectal-cancer-survivors-findings-from-the-whi-lilac-study
#12
Jessica L Krok-Schoen, Michelle J Naughton, Brittany M Bernardo, Gregory S Young, Electra D Paskett
OBJECTIVE: To examine the prevalence of and factors associated with fear of recurrence (FCR) following treatment for breast, ovarian, endometrial, and colorectal cancer among older women. METHODS: Participants were enrolled in the Women's Health Initiative WHI Life and Longevity After Cancer (LILAC) study. Descriptive statistics and multivariate logistic regression models were used to assess the association of demographic, clinical, and quality of life variables with survivors' FCR, dichotomized as <14 (low) or ≥14 (high) using the Cancer Worry Scale...
April 12, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29617712/oral-bisphosphonate-use-and-lung-cancer-incidence-among-postmenopausal-women
#13
M H Tao, S Chen, J L Freudenheim, J A Cauley, K C Johnson, X Mai, G E Sarto, H Wakelee, P Boffetta, J Wactawski-Wende
Background: Bisphosphonates are common medications for the treatment of osteoporosis in older populations. Several studies, including the Women's Health Initiative (WHI), have found inverse associations of bisphosphonate use with risk of breast and endometrial cancer, but little is known about its association with other common malignancies. The objective of this study was to evaluate the association of bisphosphonate use on the incidence of lung cancer in the WHI. Patients and methods: The association between oral bisphosphonate use and lung cancer risk was examined in 151,432 postmenopausal women enrolled into the WHI in 1993-1998...
March 29, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29611318/a-vision-for-a-microbcentric-future
#14
Ricardo Cavicchioli
Microbes are the most abundant lifeforms on the planet and perform functions critical for all other life to exist. Environmental 'omic' technologies provide the capacity to discover the 'what, how and why' of indigenous species. However, in order to accurately interpret this data, sound conceptual frameworks are required. Here I argue that our understanding of microbes will advances much more effectively if we adopt a microbcentric, and not anthropocentric view of the world.
April 2, 2018: Microbial Biotechnology
https://www.readbyqxmd.com/read/29608241/an-analysis-of-the-effect-of-statins-on-the-risk-of-non-hodgkin-s-lymphoma-in-the-women-s-health-initiative-cohort
#15
Pinkal Desai, Robert Wallace, Matthew L Anderson, Barbara V Howard, Roberta Ray, Chunyuan Wu, Monika Safford, Lisa W Martin, Nicolas Schlecht, Simin Liu, Dominic Cirillo, Allison Jay, JoAnn E Manson, Michael S Simon
Statins have been shown to induce a phosphoprotein signature that modifies MYC (myelocytomatosis viral oncogene) activation and to have anti-inflammatory activity that may impact the risk of Non-Hodgkin's lymphoma (NHL). We analyzed the relationship between statins and risk of NHL using data from the Women's Health Initiative (WHI). The study population included 161,563 postmenopausal women ages 50-79 years from which 712 cases of NHL were diagnosed after 10.8 years of follow-up. Information on statin use and other risk factors was collected by self- and interviewer-administered questionnaires...
April 2, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29545785/argr-of-streptomyces-coelicolor-is-a-pleiotropic-transcriptional-regulator-effect-on-the-transcriptome-antibiotic-production-and-differentiation-in-liquid-cultures
#16
Alma Botas, Rosario Pérez-Redondo, Antonio Rodríguez-García, Rubén Álvarez-Álvarez, Paula Yagüe, Angel Manteca, Paloma Liras
ArgR is a well-characterized transcriptional repressor controlling the expression of arginine and pyrimidine biosynthetic genes in bacteria. In this work, the biological role of Streptomyces coelicolor ArgR was analyzed by comparing the transcriptomes of S. coelicolor Δ argR and its parental strain, S. coelicolor M145, at five different times over a 66-h period. The effect of S. coelicolor ArgR was more widespread than that of the orthologous protein of Escherichia coli , affecting the expression of 1544 genes along the microarray time series...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29540343/genome-wide-dna-methylation-in-pre-diagnostic-blood-and-bladder-cancer-risk-in-the-women-s-health-initiative
#17
Kristina M Jordahl, Timothy W Randolph, Xiaoling Song, Cassandra L Sather, Lesley F Tinker, Amanda I Phipps, Karl T Kelsey, Emily White, Parveen Bhatti
BACKGROUND: Differential DNA methylation as measured in blood is a promising marker of bladder cancer susceptibility. However, previous studies have exclusively used post-diagnostic blood samples, meaning that observed associations may be markers of disease rather than susceptibility. METHODS: Genome-wide methylation was measured in pre-diagnostic blood samples, using the Illumina Infinium HumanMethylation450 Bead Array, among 440 bladder cancer cases with the transitional cell carcinoma (TCC) subtype and 440 matched cancer-free controls from the Women's Health Initiative (WHI) cohort...
March 14, 2018: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29532891/age-dependent-changes-in-vesicular-glutamate-transporter-1-and-2-expression-in-the-gerbil-hippocampus
#18
Hyo Young Jung, Dae Young Yoo, Joon Ha Park, Jong Whi Kim, Jin Young Chung, Dae Won Kim, Moo-Ho Won, Yeo Sung Yoon, In Koo Hwang
Glutamate is a major excitatory neurotransmitter that is stored in vesicles located in the presynaptic terminal. Glutamate is transported into vesicles via the vesicular glutamate transporter (VGLUT). In the present study, the age‑associated changes of the major VGLUTs, VGLUT1 and VGLUT2, in the hippocampus were investigated, based on immunohistochemistry and western blot analysis at postnatal month 1 (PM1; adolescent), PM6, PM12 (adult group), PM18 and PM24 (the aged groups). VGLUT1 immunoreactivity was primarily detected in the mossy fibers, Schaffer collaterals and stratum lacunosum‑moleculare...
March 8, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29522279/an-update-on-menopause-management
#19
REVIEW
Katherine Ward, Angela Deneris
Menopause-related symptoms frequently lead women to seek health care. Recommendations for prescribing hormone therapy have changed significantly since the publication of initial results from the Women's Health Initiative (WHI) study in 2002. The North American Menopause Society and the American College of Obstetricians and Gynecologists have newer guidelines based on long-term analyses of the WHI participants as well as emerging data from other clinical trials. Women with an intact uterus who are using systemic estrogen must also use a progestogen; however, there are 2 new selective estrogen receptor modulators on the market for use without a progestogen...
March 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29520604/estrogen-therapy-for-osteoporosis-in-the-modern-era
#20
REVIEW
V A Levin, X Jiang, R Kagan
Menopause predisposes women to osteoporosis due to declining estrogen levels. This results in a decrease in bone mineral density (BMD) and an increase in fractures. Osteoporotic fractures lead to substantial morbidity and mortality, and are considered one of the largest public health priorities by the World Health Organization (WHO). It is therefore essential for menopausal women to receive appropriate guidance for the prevention and management of osteoporosis. The Women's Health Initiative (WHI) randomized controlled trial first proved hormonal therapy (HT) reduces the incidence of all osteoporosis-related fractures in postmenopausal women...
May 2018: Osteoporosis International
keyword
keyword
64994
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"