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Pathological gambling

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https://www.readbyqxmd.com/read/29353301/the-efficacy-of-motivational-intervention-and-cognitive-behavioral-therapy-for-pathological-gambling
#1
Anna Garcia-Caballero, Marina Torrens-Lluch, Isabel Ramírez-Gendrau, Gemma Garrido, Vicenç Vallès, Núria Aragay
The aim of the current study is to determine the effectiveness of an individual psychological intervention based on the motivational interview and cognitive-behavioral therapy for the treatment of pathological gambling. A sample of 18 participants, diagnosed of pathological gambling and without any other associated comorbidity, were assessed, attended at the publicly-funded Gambling and Behavioral Addictions Unit (Consorci Sanitari de Terrassa). Median age was 46 years (SD = 12). All the patients achieved abstinence and completed follow-up...
January 15, 2018: Adicciones
https://www.readbyqxmd.com/read/29345864/naltrexone-and-disulfiram-treatment-response-in-veterans-with-alcohol-dependence-and-co-occurring-problem-gambling-features
#2
Jon E Grant, Marc N Potenza, Shane W Kraus, Ismene L Petrakis
BACKGROUND: Disordered gambling behavior frequently co-occurs with alcohol dependence and other psychiatric conditions. Using data from a previously published trial, we conducted secondary analyses to examine the influence of problem-gambling features on treatment outcome for alcohol dependence or co-occurring psychopathology assessed via DSM-IV criteria. METHODS: Two hundred fifty-four patients with alcohol dependence and co-occurring psychiatric disorders were treated for 12 weeks in an outpatient medication study conducted at 3 Veterans Administration outpatient clinics from October 1998 to March 2002...
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29339820/histone-variant-macroh2a1-plays-an-isoform-specific-role-in-suppressing-epithelial-mesenchymal-transition
#3
Dayle Q Hodge, Jihong Cui, Matthew J Gamble, Wenjun Guo
Epithelial-Mesenchymal Transition (EMT) is a biological program that plays key roles in various developmental and pathological processes. Although much work has been done on signaling pathways and transcription factors regulating EMT, the epigenetic regulation of EMT remains not well understood. Histone variants have been recognized as a key group of epigenetic regulators. Among them, macroH2A1 is involved in stem cell reprogramming and cancer progression. We postulated that macroH2A1 may play a role in EMT, a process involving reprogramming of cellular states...
January 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29297862/estimate-of-the-prevalence-of-subjects-with-gambling-related-problems-requiring-treatment-a-study-in-northern-italy
#4
Raimondo Maria Pavarin, Corrado Zenesini, Angelo Fioritti
This study analyzes the data related to subjects who for the first time turned to a hospital or to a Public Treatment Service Dedicated to Drug Addicts or to a Community Mental Health Center for problems related to pathological gambling in the metropolitan area of Bologna (Northern Italy) in the period 2000/2015. The aims were to describe characteristics and problems of pathological gamblers (PGs), and to estimate the prevalence of PGs using the capture-recapture method. Four hundred and ninety-five residents were identified, with an estimate of 1570 PGs and a prevalence of 1...
October 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/29280397/measures-of-behavioral-function-predict-duration-of-video-game-play-utilization-of-the-video-game-functional-assessment-revised
#5
Frank D Buono, Mark D Griffiths, Matthew E Sprong, Daniel P Lloyd, Ryan M Sullivan, Thomas D Upton
Background Internet gaming disorder (IGD) was introduced in the DSM-5 as a way of identifying and diagnosing problematic video game play. However, the use of the diagnosis is constrained, as it shares criteria with other addictive orders (e.g., pathological gambling). Aims Further work is required to better understand IGD. One potential avenue of investigation is IGD's relationship to the primary reinforcing behavioral functions. This study explores the relationship between duration of video game play and the reinforcing behavioral functions that may motivate or maintain video gaming...
December 1, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29238309/who-seeks-treatment-when-medicine-opens-the-door-to-pathological-gambling-patients-psychiatric-comorbidity-and-heavy-predominance-of-online-gambling
#6
Anders Håkansson, Emma Mårdhed, Mats Zaar
Background: Few studies have assessed treatment-seeking behavior and patient characteristics in pathological gambling focusing on psychiatric comorbidity, particularly in a setting of heavy exposure to online gambling. This study aimed to address patient characteristics in a novel health care-based treatment modality for pathological gambling, including potential associations between gambling types, psychiatric comorbidity, and gender. Methods: All patients undergoing structured assessment between January 2016 and April 2017 were included (N = 106), and patient records were reviewed for cooccurring psychiatric disorders and types of problem games...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29226267/orbitofrontal-cortex-activity-and-connectivity-predict-future-depression-symptoms-in-adolescence
#7
Jingwen Jin, Ananth Narayanan, Greg Perlman, Katherine Luking, Christine DeLorenzo, Greg Hajcak, Daniel N Klein, Roman Kotov, Aprajita Mohanty
Background: Major depressive disorder is a leading cause of disability worldwide; however, little is known about pathological mechanisms involved in its development. Research in adolescent depression has focused on reward sensitivity and striatal mechanisms implementing it. The contribution of loss sensitivity to future depression, as well as the orbitofrontal cortex (OFC) mechanisms critical for processing losses and rewards, remain unexplored. Furthermore, it is unclear whether OFC functioning interacts with familial history in predicting future depression...
October 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29189190/role-of-repetitive-transcranial-magnetic-stimulation-rtms-in-treatment-of-addiction-and-related-disorders-a-systematic-review
#8
Ramkrishna Makani, Basant Pradhan, Umang Shah, Tapan Parikh
BACKGROUND: Addiction and related disorders are devastating with their tremendous social, psychological, and physical consequences for which development of optimally effective treatments are long overdue. Repetitive transcranial magnetic stimulation (rTMS) is relatively safe and is becoming an emerging therapeutic tool for these conditions. METHODS: This systematic review was conducted using PubMed, PsycINFO, PsychiatryOnline and Cochrane Library ranging from year 2001 to 2017...
November 29, 2017: Current Drug Abuse Reviews
https://www.readbyqxmd.com/read/29176580/reduced-loss-aversion-in-pathological-gambling-and-alcohol-dependence-is-associated-with-differential-alterations-in-amygdala-and-prefrontal-functioning
#9
Alexander Genauck, Saskia Quester, Torsten Wüstenberg, Chantal Mörsen, Andreas Heinz, Nina Romanczuk-Seiferth
Diagnostic criteria for pathological gambling and alcohol dependence (AD) include repeated addictive behavior despite severe negative consequences. However, the concept of loss aversion (LA) as a facet of value-based decision making has not yet been used to directly compare these disorders. We hypothesized reduced LA in pathological gamblers (PG) and AD patients, correlation of LA with disorder severity, and reduced loss-related modulation of brain activity. 19 PG subjects, 15 AD patients and 17 healthy controls (HC) engaged in a LA task in a functional magnetic resonance imaging setting...
November 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29157488/l%C3%A2-hypophyse-et-ses-traitements-comment-peuvent-ils-influer-sur-le-comportement-the-pituitary-and-its-treatments-how-can-they-influence-behaviour
#10
C Mouly, F Borson-Chazot, P Caron
Behaviour may be influenced by pituitary hormones or treatments. Dopamine agonist (DA) indicated in prolactinomas treatment can cause side effects, and especially impulse control disorders. In the context of prolactinomas treatment, impulse control disorders (ICD) have been reported like gambling, compulsive shopping, but mostly hypersexuality. These ICD can occur with low AD doses, and seem to be independent of type of molecule and psychiatric medical history. The main pathophysiologic hypothesis is a dysregulation of dopaminergic pathway involved in reward system...
October 2017: Annales D'endocrinologie
https://www.readbyqxmd.com/read/29134496/an-analysis-of-treatment-seeking-behavior-in-individuals-with-gambling-disorder
#11
Michael D Harries, Sarah A Redden, Jon E Grant
Gambling disorder affects approximately 1.1-3.5% of the population, with the rates being higher in young adults. Despite this high prevalence, little is known regarding which pathological gamblers decide to seek treatment. This study sought to examine the differences in three groups of pathological gamblers: those who did not seek treatment (n = 94), those who sought therapy (n = 106) and those who sought medication therapy (n = 680). All subjects were assessed on a variety of measures including demographics, family history, gambling history, comorbid psychiatric disorders and an assortment of clinical variables such as the Quality of Life Inventory, Hamilton Depression and Anxiety Rating Scales, Yale Brown Obsessive Compulsive Scale for Pathologic Gambling (PG-YBOCS), Barratt Impulsiveness Scale, Eysenck Impulsiveness Questionnaire and select cognitive tasks...
November 13, 2017: Journal of Gambling Studies
https://www.readbyqxmd.com/read/29110644/the-protective-role-of-religiosity-against-problem-gambling-findings-from-a-five-year-prospective-study
#12
Seema Mutti-Packer, David C Hodgins, Robert J Williams, Barna Konkolÿ Thege
BACKGROUND: Little research has examined the potential protective influence of religiosity against problem gambling; a common addictive behavior, and one with a host of associated negative health and social outcomes. The aims of this study were to examine (1) the potential longitudinal association between religiosity and problem gambling among adults and (2) the potential moderating role of gender on this association. METHODS: Data were from five waves of the Quinte Longitudinal Study (QLS), between 2006 and 2010...
November 6, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29105942/the-prevalence-incidence-and-gender-and-age-specific-incidence-of-problem-gambling-results-of-the-swedish-longitudinal-gambling-study-swelogs
#13
Max Abbott, Ulla Romild, Rachel Volberg
AIMS: To estimate the prevalence, incidence, and gender and age-specific incidence of problem gambling in the Swedish adult population. DESIGN: Longitudinal cohort study with linkage to register data. SETTING: Sweden. PARTICIPANTS: Stratified random sample aged 16-84 at baseline (n = 8,165) re-assessed a year later (n = 6,021). MEASUREMENTS: Problem gambling (lifetime and past 12 months) was measured by the South Oaks Gambling Screen-Revised (SOGS-R)...
November 4, 2017: Addiction
https://www.readbyqxmd.com/read/29098673/biochemical-diagnosis-in-substance-and-non-substance-addiction
#14
Wenwen Shen, Huifeng Liu, Xiaohu Xie, Haixiong Liu, Wenhua Zhou
An optimal biochemical marker for addiction would be some easily traced molecules in body specimens, which indicates indulgent addictive behaviors, or susceptibility to certain addictive stimuli. In this chapter, we discussed existing literature about possible biomarkers, and classified them into three categories: origin forms and metabolites of substances, markers from biochemical responses to certain addiction, and genetic and epigenetic biomarkers suggesting susceptibility to addiction. In every category, we examined studies concerning certain type of addiction one by one, with focuses mainly on opiates, psychostimulants, and pathological gambling...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29098672/similarities-and-differences-in-diagnostic-scales
#15
Bin Xuan, Peng Li, Liping Yang, Mingzhu Li, Jing Zhou
A scale plays an important role as a diagnostic tool in discriminating between addicts and non-addicts. At the beginning of this chapter, we have briefly introduced the development of substance and non-substance addiction scales, which not only include alcohol addiction, nicotine addiction and pathological gambling, but also the disputed exercise and sex addiction. While it was found that almost all addiction scales contain items relating to social impairment, preoccupation, withdrawal, and tolerance, the variability is more pronounced with non-substance addiction scales...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29098669/similarities-and-differences-in-neuroimaging
#16
Yan-Kun Sun, Yan Sun, Xiao Lin, Lin Lu, Jie Shi
Addiction is a chronically relapsing disease characterized by drug intoxication, craving, bingeing, and withdrawal with loss of control. An increasing number of studies have indicated that non-substance addiction, like internet addiction and pathological gambling, share clinical, phenomenological, and biological features with substance addiction. With the development of imaging technology in the past three decades, neuroimaging studies have provided information on the neurobiological effects, and revealed neurochemical and functional changes in the brains of both drug-addicted and non-substance addicted subjects...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29098668/similarities-and-differences-in-genetics
#17
Yang Zhang, Yan Sun, Jie Liang, Lin Lu, Jie Shi
Similar symptomatology manifestations and high co-morbidity in substance and non-substance addictions suggest that there may be a common pathogenesis between them. Associated with impulse control and emotional processing, the monoamine neurotransmitter system genes are suggested to be related to both substance and non-substance addictions, such as dopamine (DA) system, 5-hydroxytryptamine/serotonin (5-HT) system, the endogenous opioid system and so on. Here we reviewed the similarities and differences in genetics between classic substance addiction and common types of non-substance addiction, e...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29098666/definition-of-substance-and-non-substance-addiction
#18
Zhiling Zou, Huijun Wang, Federico d'Oleire Uquillas, Xiaomei Wang, Jianrui Ding, Hong Chen
Substance addiction (or drug addiction) is a neuropsychiatric disorder characterized by a recurring desire to continue taking the drug despite harmful consequences. Non-substance addiction (or behavioral addiction) covers pathological gambling, food addiction, internet addiction, and mobile phone addiction. Their definition is similar to drug addiction but they differ from each other in specific domains. This review aims to provide a brief overview of past and current definitions of substance and non-substance addiction, and also touches on the topic of diagnosing drug addiction and non-drug addiction, ultimately aiming to further the understanding of the key concepts needed for a foundation to study the biological and psychological underpinnings of addiction disorders...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29094622/long-term-effects-of-internet-supported-cognitive-behaviour-therapy
#19
Gerhard Andersson, Alexander Rozental, Roz Shafran, Per Carlbring
Internet-supported and therapist-guided cognitive behaviour therapy (ICBT) is effective for a range of problems in the short run, but less is known about the long-term effects with follow-ups of two years or longer. Areas covered: This paper reviews studies in which the long-term effects of guided ICBT were investigated. Following literature searches in PubMed and other sources meta-analytic statistics were calculated for 14 studies involving a total of 902 participants, and an average follow-up period of three years...
November 2, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/29091825/stress-moderates-the-relationships-between-problem-gambling-severity-and-specific-psychopathologies
#20
Silvia Ronzitti, Shane W Kraus, Rani A Hoff, Marc N Potenza
The purpose of this study was to examine the extent to which stress moderated the relationships between problem-gambling severity and psychopathologies. We analyzed Wave-1 data from 41,869 participants of the National Epidemiologic Survey of Alcohol and Related Conditions (NESARC). Logistic regression showed that as compared to a non-gambling (NG) group, individuals at-risk gambling (ARG) and problem gambling (PPG) demonstrated higher odds of multiple Axis-I and Axis-II disorders in both high- and low-stress groups...
October 22, 2017: Psychiatry Research
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