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ischemic cardiopathy

Simona Lattanzi, Claudia Cagnetti, Alessandra Pulcini, Marco Morelli, Simone Maffei, Leandro Provinciali, Mauro Silvestrini
BACKGROUND: The Embolic Stroke of Undetermined Source (ESUS) is a recently developed clinical construct which describes stroke patients for whom the embolic source remains undetermined despite recommended investigations. The aim of the study was to characterize the ESUS population according to the abnormality in the P-wave terminal force in lead V1 (PTFV1). METHODS: We retrospectively identified consecutive patients hospitalized for acute ischemic stroke who met the ESUS diagnostic criteria...
April 15, 2017: Journal of the Neurological Sciences
Shadi Yaghi, Richard A Bernstein, Rod Passman, Peter M Okin, Karen L Furie
BACKGROUND: Cryptogenic stroke accounts for 30% to 40% of ischemic stroke. It is essential to determine the possible culprit because this will improve secondary stroke prevention strategies. METHODS: We performed a narrative nonsystematic review of the literature that included randomized trials, exploratory comparative studies, and case series on cryptogenic stroke. RESULTS: There are several possible mechanisms implicated in cryptogenic stroke, including occult paroxysmal atrial fibrillation, patent foramen ovale, aortic arch atherosclerosis, atrial cardiopathy, and substenotic atherosclerosis...
February 3, 2017: Circulation Research
Jean-Thomas Vilquin, Jessy Etienne
Heart failure is a major concern for public health systems, and several approaches of cellular therapy are being investigated with the goal of improving the function of these failing hearts. Many cell types have been used (skeletal myoblasts, hematopoietic, endothelial or mesenchymal progenitors, cardiac cells…), most often in the indication of post-ischemic heart failure rather than in the indication of genetic dilated cardiomyopathy. It is easier, indeed, to target a restricted area than the whole myocardium...
November 2016: Médecine Sciences: M/S
H Gutiérrez-Leonard, E Martínez-Lara, A E Fierro-Macías, V M Mena-Burciaga, M D Ronquillo-Sánchez, E Floriano-Sánchez, N Cárdenas-Rodríguez
BACKGROUND: Cardiovascular disease is the leading cause of death in the Western world, and a major cause of this disease is atherosclerosis. Research has demonstrated that pregnancy-associated plasma protein A (PAPP-A) plays a role in cardiovascular disease, as evidenced by the association between PAPP-A and severity of heart damage. AIM: The aim of this work was to investigate the correlation between PAPP-A concentrations in coronary and peripheral blood and certain clinicopathological factors and antioxidant enzyme activities in patients diagnosed with coronary artery disease...
October 11, 2016: Irish Journal of Medical Science
Massimo Sandrini, Valerio Vizzardi, Francesca Valerio, Sara Ravera, Luigi Manili, Roberto Zubani, Bernardo J A Lucca, Giovanni Cancarini
INTRODUCTION: Incremental dialysis consists in prescribing a dialysis dose aimed towards maintaining total solute clearance (renal + dialysis) near the targets set by guidelines. Incremental peritoneal dialysis (incrPD) is defined as one or two dwell-times per day on CAPD, whereas standard peritoneal dialysis (stPD) consists in three-four dwell-times per day. PATIENTS AND METHODS: Single-centre cohort study. Enrollement period: January 2002-December 2007; end of follow up (FU): December 2012...
December 2016: Journal of Nephrology
David Sacerdoti, Paola Pesce, Marco Di Pascoli, Massimo Bolognesi
Epoxygenase-dependent metabolites of arachidonc acid, EETs and the heme-oxygenase (HO)-1/carbon monoxide/bilverdin system share similarities in their activity and mediators. They control endothelial function, dilating small arterial vessels, decrease blood pressure, protect the heart from ischemic and hypertensive cardiopathy, control renal circulation and function, promote angiogenesis and organ regeneration, oppose oxidative stress and inflammation, improve diabetes and obesity, have protective effects on the liver, and participate in portal hypertension...
September 2016: Prostaglandins & Other Lipid Mediators
Peter M Okin, Hooman Kamel, Sverre E Kjeldsen, Richard B Devereux
BACKGROUND: Recent findings in population-based studies suggest that abnormal P wave terminal force in lead V1 (PTFV1), a marker of left atrial abnormalities such as fibrosis, dilatation and elevated filling pressures, is associated with incident ischemic stroke, even in the absence of atrial fibrillation. However, whether PTFV1 predicts incident stroke in hypertensive patients during blood pressure lowering has not been examined. METHODS: Risk of incident stroke was examined in relation to abnormal PTFV1 on a baseline ECG in 7778 hypertensive patients with ECG left ventricular hypertrophy, no history of atrial fibrillation, in sinus rhythm on their baseline ECG with no incident atrial fibrillation during follow-up, who were randomly assigned to losartan-based or atenolol-based treatment...
September 2016: Journal of Hypertension
Sergio Papagni, Carmen Bonifati, Filippo Dagostino, Angelo Marco Murgo
Drug-induced liver injury is a frequent cause of acute liver failure. It may cause clinical manifestations ranging from simple alteration of the common liver function tests until more severe manifestations including encephalopathy, coagulopathy, and in many cases progressive multi-organ dysfunction. The condition, therefore, may be associated with higher morbidity and mortality as well as higher consumption of economic resources. In this paper, we present the case of a 71-year-old patient treated with hemodialysis, diabetic, with ischemic cardiopathy and severe peripheral vascular disease...
January 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
Eva Giralt-Steinhauer, Elisa Cuadrado-Godia, Carolina Soriano-Tárraga, Ángel Ois, Jordi Jiménez-Conde, Ana Rodríguez-Campello, Alejandra Gómez-González, Elena Muiño-Acuña, Isaac Subirana-Cachinero, Jaume Roquer
INTRODUCTION: The aims of this study are to describe the incidence of paroxysmal atrial fibrillation (pAF) in patients with ischemic stroke (IS) or transient ischemic attack (TIA), and to create a risk prediction model, using immediately available clinical data associated with new pAF diagnosis. METHODS: We analyzed data from the BASICMAR stroke register, with 5 inclusion criteria: (1) diagnosis of IS/TIA; (2) no history of AF or structural cardiopathy; (3) stroke unit (SU) monitoring after normal electrocardiogram in the emergency room; (4) complete etiologic study; and (5) 3-month follow-up...
2015: European Neurology
Guillermo A Keller, Paulino A Alvarez, Marcelo L Ponte, Waldo H Belloso, Claudia Bagnes, Cecilia Sparanochia, Claudio D Gonzalez, M Cecilia Villa Etchegoyen, Roberto A Diez, Guillermo Di Girolamo
OBJECTIVE: The actual prevalence of drug induced QTc prolongation in clinical practice is unknown. Our objective was to determine the occurrence and characteristics of drug-induced QT prolongation in several common clinical practices. Additionally, a subgroup of patients treated with dextropropoxyphene of particular interest for the regulatory authority was analysed. RESEARCH DESIGN AND METHODS: Medical history and comorbidities predisposing to QT interval prolongation were registered for 1270 patient requiring medical assistance that involved drug administration...
2016: Current Drug Safety
Shadi Yaghi, Amelia K Boehme, Rebecca Hazan, Eldad A Hod, Alberto Canaan, Howard F Andrews, Hooman Kamel, Randolph S Marshall, Mitchell S V Elkind
BACKGROUND: There is increasing evidence that left atrial dysfunction or cardiopathy is associated with ischemic stroke risk independently of atrial fibrillation. We aimed to determine the prevalence of atrial cardiopathy biomarkers in patients with cryptogenic stroke. METHODS: We included consecutive patients with ischemic stroke enrolled in the New York Columbia Collaborative Specialized Program of Translational Research in Acute Stroke registry between December 1, 2008, and April 30, 2012...
January 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
M Matura-Bedouhene, A Maatouk, F Moulin, E Welter, O Morel, E Perdriolle-Galet
Heart diseases complicate 1 to 3% of pregnancies and are the leading cause of indirect maternal deaths. Prior ischaemic heart event in pregnant patients is increasing. Most knowledge is based on few reports and there are no French nor international recommendations about the specific management of these patients. The specificity of the management of these patients during pregnancy, delivery and post-partum depends on the severity of the prior cardiac event and its consequences. This will be illustrated by the report of four recent cases managed in our hospital...
April 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
Qiming Dai, Jing Lu, Benwen Wang, Genshan Ma
This study aimed to investigate the clinical feasibility and effects of percutaneous renal sympathetic nerve radiofrequency ablation in patients with heart failure. A total of 20 patients with heart failure were enrolled, aged from 47 to 75 years (63±10 years). They were divided into the standard therapy (n = 10), and renal nerve radiofrequency ablation groups (n = 10). There were 15 males and 5 female patients, including 8 ischemic cardiomyopathy, 8 dilated cardiomyopathy, and 8 hypertensive cardiopathy. All of the patients met the criteria of New York Heart Association classes III-IV cardiac function...
2015: International Journal of Clinical and Experimental Medicine
D Maione, A Fg Cicero, S Bacchelli, E R Cosentino, D Degli Esposti, D N Manners, E R Rinaldi, M Rosticci, R Senaldi, E Ambrosioni, C Borghi
To propose a test to evaluate endothelial function, based on VO(2) on-transition kinetics in sub-anaerobic threshold (AT) constant load exercise, we tested healthy subjects and patients with ischemic-hypertensive cardiopathy by two cardiopulmonary tests on a cycle ergometer endowed with an electric motor to overcome initial inertia: a pre-test and, after at least 24 h, one 6 min constant load exercise at 90 % AT. We measured net phase 3 VO(2)-on kinetics and, by phase 2 time constant (tau), valued endothelial dysfunction...
2015: Physiological Research
Andreas Scherr, Bruno Seifert, Martin Kuster, Anja Meyer, Karl-Olov Fagerstroem, Michael Tamm, Daiana Stolz
BACKGROUND: Concerns about postcessational weight gain might hamper rather than encourage smokers to quit smoking. METHODS: We conducted a comprehensive multi-institutional smoking cessation program for health care and industrial workers (n = 654) employed at University Hospital Basel (Switzerland) and two local health industry companies (Novartis International AG, F. Hoffmann-La Roche AG). The program contained counselling with an option of pharmacological support...
2015: BMC Public Health
Hooman Kamel, Peter M Okin, W T Longstreth, Mitchell S V Elkind, Elsayed Z Soliman
Atrial fibrillation (AF) has long been associated with a heightened risk of ischemic stroke and systemic thromboembolism, but recent data require a re-evaluation of our understanding of the nature of this relationship. New findings about the temporal connection between AF and stroke, alongside evidence linking markers of left atrial abnormalities with stroke in the absence of apparent AF, suggest that left atrial thromboembolism may occur even without AF. These observations undermine the hypothesis that the dysrhythmia that defines AF is necessary and sufficient to cause thromboembolism...
May 2015: Future Cardiology
Juan Carlos Regueiro Lopez, Enrique Gomez Gomez, Alberto Alonso Carrillo, Roque Cano Castineira, Maria Jose Requena Tapia
OBJECTIVE: To review the technique and outcome of perineal urethrostomy or urethral perineostomy and to identify factors related to the procedure failure. MATERIAL AND METHODS: We studied 17 patients who underwent perineal urethrostomy between 2009-2013 in a single hospital. Success was defined as no need for additional surgical treatment or urethral dilatation. We reviewed the clinical data related to age, weight, previous urethral surgery, diabetes, hypertension, ischemic cardiopathy, lichen sclerosus and other causes and studied their association with the procedure failure (univariate analysis)...
January 2015: International Braz J Urol: Official Journal of the Brazilian Society of Urology
C Marcu
No abstract text is available yet for this article.
January 1982: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
Giusto Viglino, Loris Neri, Mauro Feola
INTRODUCTION: Peritoneal ultrafiltration (PUF) is proposed in the long-term treatment of congestive heart insufficiency. However, the data in literature available at present do not allow for conclusive meta-analysis. OBJECTIVE/MATERIALS AND METHODS: A systematic review of the literature (MEDLINE-EMBASE, 01/01/2003-31/12/2013, studies with ≥4 patients, adults, non-ESRD) to highlight which patients PUF has been used in, how and with what results. RESULTS: Consideration was given to 14 papers for a total of 471 patients...
February 2015: Journal of Nephrology
José Angel González-Pliego, Daniel Hernández-Gordillo, Edgar Castañeda-Barragán, Leopoldo García-Lamas, César Manuel Guzmán-Sánchez
The purpose of this review is to analyse the relation between obstructive sleep apnea and coronary disease. We present epidemiological data on the respiratory disorder and its association with ischemic cardiopathy, as well as common cardiovascular risk factors, physiopathological interactions between both conditions, clinical evolution and impact of treatment on prognosis.
January 2015: Archivos de Cardiología de México
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