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https://www.readbyqxmd.com/read/28737619/revision-total-elbow-arthroplasty
#1
Miguel A Ramirez, Emilie V Cheung, Anand M Murthi
Despite recent technologic advances, total elbow arthroplasty has complication rates higher than that of total joint arthroplasty in other joints. With new antirheumatic treatments, the population receiving total elbow arthroplasty has shifted from patients with rheumatoid arthritis to those with posttraumatic arthritis, further compounding the high complication rate. The most common reasons for revision include infection, aseptic loosening, fracture, and component failure. Common mechanisms of total elbow arthroplasty failure include infection, aseptic loosening, fracture, component failure, and instability...
August 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28710527/assessment-of-surface-water-contamination-from-coalbed-methane-fracturing-derived-volatile-contaminants-in-sullivan-county-indiana-usa
#2
Nicholas Meszaros, Bikram Subedi, Tristan Stamets, Naima Shifa
There is a growing concern over the contamination of surface water and the associated environmental and public health consequences from the recent proliferation of hydraulic fracturing in the USA. Petroleum hydrocarbon-derived contaminants of concern [benzene, toluene, ethylbenzene, and xylenes (BTEX)] and various dissolved cations and anions were spatially determined in surface waters around 15 coalbed methane fracking wells in Sullivan County, IN, USA. At least one BTEX compound was detected in 69% of sampling sites (n = 13) and 23% of sampling sites were found to be contaminated with all of the BTEX compounds...
July 14, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28709676/fracture-load-of-complete-arch-implant-supported-prostheses-reinforced-with-nylon-silica-mesh-an-in%C3%A2-vitro-study
#3
Fernanda de Cássia Papaiz Gonçalves, Marina Amaral, Alexandre Luiz Souto Borges, Luiz Fernando Martins Gonçalves, Tarcisio José de Arruda Paes-Junior
STATEMENT OF PROBLEM: Complete-arch implant-supported prostheses without a framework have a high risk of failure: a straightforward and inexpensive reinforcement material, such as nylon mesh, could improve their longevity. PURPOSE: The purpose of this in vitro study was to evaluate a nylon-silica mesh compound on the fracture strength of acrylic resin and the fracture load of complete-arch implant-supported prostheses. MATERIAL AND METHODS: Twenty-four complete mandibular arch implant-supported prostheses were divided into 2 groups according to cantilever length (molar and premolar) and subdivided into another 2 subgroups according to the presence or absence of reinforcing mesh...
July 11, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28697484/organic-compounds-in-hydraulic-fracturing-fluids-and-wastewaters-a-review
#4
REVIEW
Jenna L Luek, Michael Gonsior
High volume hydraulic fracturing (HVHF) of shale to stimulate the release of natural gas produces a large quantity of wastewater in the form of flowback fluids and produced water. These wastewaters are highly variable in their composition and contain a mixture of fracturing fluid additives, geogenic inorganic and organic substances, and transformation products. The qualitative and quantitative analyses of organic compounds identified in HVHF fluids, flowback fluids, and produced waters are reviewed here to communicate knowledge gaps that exist in the composition of HVHF wastewaters...
July 5, 2017: Water Research
https://www.readbyqxmd.com/read/28691101/advancing-discontinuous-fiber-reinforced-composites-above-critical-length-for-replacing-current-dental-composites-and-amalgam
#5
Richard C Petersen
Clinicians have been aware that posterior dental particulate-filled composites (PFCs) have many placement disadvantages and indeed fail clinically at an average rate faster than amalgam alloys. Secondary caries is most commonly identified as the chief failure mechanism for both dental PFCs and amalgam. In terms of a solution, fiber-reinforced composites (FRCs) above critical length (Lc) can provide mechanical property safety factors with compound molding packing qualities to reduce many problems associated with dental PFCs...
February 2017: Journal of Nature and Science
https://www.readbyqxmd.com/read/28689769/osteoporosis-treatment-recent-developments-and-ongoing-challenges
#6
REVIEW
Sundeep Khosla, Lorenz C Hofbauer
Osteoporosis is an enormous and growing public health problem. Once considered an inevitable consequence of ageing, it is now eminently preventable and treatable. Ironically, despite tremendous therapeutic advances, there is an increasing treatment gap for patients at high fracture risk. In this Series paper, we trace the evolution of drug therapy for osteoporosis, which began in the 1940s with the demonstration by Fuller Albright that treatment with oestrogen could reverse the negative calcium balance that developed in women after menopause or oophorectomy...
July 6, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28689388/osteoblast-and-bacterial-culture-from-cryopreserved-skull-flap-after-craniectomy-laboratory-study
#7
Tack Geun Cho, Suk Hyung Kang, Yong Jun Cho, Hyuk Jai Choi, Jin Pyeong Jeon, Jin Seo Yang
OBJECTIVE: Cranioplasty using a cryopreserved skull flap is a wide spread practice. The most well-known complications of cranioplasty are postoperative surgical infections and bone flap resorption. In order to find biological evidence of cryopreserved cranioplasty, we investigated microorganism contamination of cryopreserved skulls and cultured osteoblasts from cryopreserved skulls. METHODS: Cryopreserved skull flaps of expired patients stored in a bone bank were used...
July 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28634473/toxic-effects-of-prodigiosin-secreted-by-hahella-sp-ka22-on-harmful-alga-phaeocystis-globosa
#8
Huajun Zhang, Hui Wang, Wei Zheng, Zhiyuan Yao, Yun Peng, Su Zhang, Zhong Hu, Zhen Tao, Tianling Zheng
Application of algicidal compounds secreted by bacteria is a promising and environmentally friendly strategy to control harmful algal blooms (HABs). Years ago prodigiosin was described as an efficient algicidal compound, but the details about the effect of prodigiosin on algal cells are still elusive. Prodigiosin shows high algicidal activity on Phaeocystis globosa, making it a potential algicide in HAB control. When P. globosa were treated with prodigiosin at 5 μg/mL, algae cells showed cytoplasmic hypervacuolization, chloroplast and nucleus rupture, flagella missing, and cell fracture, when observed by scanning electron microscope and transmission electron microscopy...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28622807/the-comparison-of-the-effects-of-a-novel-hydrogel-compound-and-traditional-hyaluronate-following-micro-fracture-procedure-in-a-rat-full-thickness-chondral-defect-model
#9
Yunus Emre Akman, Erhan Sukur, Ahmet Senel, Nur Ece Oztas Sukur, Canan Kelten Talu, Yusuf Ozturkmen
PURPOSE: The aim of this experimental study was to investigate the impact of HA-CS-NAG compound (hyaluronate, sodium chondroitin sulfate, N-acetyl-d-glucosamine) on the quality of repair tissue after micro-fracture and to compare it with HA (hyaluronat), in a rat full-thickness chondral defect model. METHODS: Full-thickness chondral defects were created in a non-weight bearing area by using a handle 2.7-mm drill bit, in the right knees of 33 Sprague-Dawley rats...
June 13, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28616231/lymph-node-transfer-for-refractory-infectious-sites-caused-by-trauma
#10
Makoto Mihara, Hisako Hara, Kazuki Kikuchi
OBJECTIVE: In this report, we placed focus on the immunological function of lymph nodes and performed lymph node transfer via a free flap to a site of refractory infection. CASE AND RESULTS: Case 1 describes a 34-year-old male suffering from compound fractures with severe crush injuries and burns in the right ankle joint. A 20 × 15 cm skin defect was observed around the right malleolus medialis, along with denuded tendons with bacterial infection. After conservative treatment, we transferred a lymph-node-containing free superficial circumflex iliac artery perforator flap to the region, with minimum debridement...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28606129/impairment-of-early-fracture-healing-by-skeletal-muscle-trauma-is-restored-by-fk506
#11
Brady J Hurtgen, Beth E P Henderson, Catherine L Ward, Stephen M Goldman, Koyal Garg, Todd O McKinley, Sarah M Greising, Joseph C Wenke, Benjamin T Corona
BACKGROUND: Heightened local inflammation due to muscle trauma or disease is associated with impaired bone regeneration. METHODS: We hypothesized that FK506, an FDA approved immunomodulatory compound with neurotrophic and osteogenic effects, will rescue the early phase of fracture healing which is impaired by concomitant muscle trauma in male (~4 months old) Lewis rats. FK506 (1 mg/kg; i.p.) or saline was administered systemically for 14 days after an endogenously healing tibia osteotomy was created and fixed with an intermedullary pin, and the overlying tibialis anterior (TA) muscle was either left uninjured or incurred volumetric muscle loss injury (6 mm full thickness biopsy from middle third of the muscle)...
June 12, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28600151/splenomegaly-myeloid-lineage-expansion-and-increased-osteoclastogenesis-in-osteogenesis-imperfecta-murine
#12
Brya G Matthews, Emilie Roeder, Xi Wang, Hector Leonardo Aguila, Sun-Kyeong Lee, Danka Grcevic, Ivo Kalajzic
Osteogenesis imperfecta (OI) is a disease caused by defects in type I collagen production that results in brittle bones. While the pathology is mainly caused by defects in the osteoblast lineage, there is also elevated bone resorption by osteoclasts resulting in high bone turnover in severe forms of the disease. Osteoclasts originate from hematopoietic myeloid cells, however changes in hematopoiesis have not been previously documented in OI. In this study, we evaluated hematopoietic lineage distribution and osteoclast progenitor cell frequency in bone marrow, spleen and peripheral blood of osteogenesis imperfecta murine (OIM) mice, a model of severe OI...
June 7, 2017: Bone
https://www.readbyqxmd.com/read/28593627/efficacy-and-safety-of-using-n-butyl-cyanoacrylate-in-fixation-of-cranial-following-trauma-and-other-pathologies
#13
Ahmed Sultan, Abbas Mohamed
Skull Bone fixation following different cranial surgeries is essential and should be rigid, simple and cheap. We describe our technique of cranial fixation using the adhesive cyanoacrylates. MATERIALS AND METHODS: At the end of cranial and intracranial surgeries the craniotomy flap and bone pieces are returned, realigned and fixed using Histoacryl® (N-Butyl Cyanoacrylate) glue. The glue is applied all around the flap in 360 degrees fashion. RESULT: The adhesive material was used in 24 cases after different surgeries involving the calvaria of the skull...
April 30, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28591666/characterization-of-the-chemicals-used-in-hydraulic-fracturing-fluids-for-wells-located-in-the-marcellus-shale-play
#14
Huan Chen, Kimberly E Carter
Hydraulic fracturing, coupled with the advances in horizontal drilling, has been used for recovering oil and natural gas from shale formations and has aided in increasing the production of these energy resources. The large volumes of hydraulic fracturing fluids used in this technology contain chemical additives, which may be toxic organics or produce toxic degradation byproducts. This paper investigated the chemicals introduced into the hydraulic fracturing fluids for completed wells located in Pennsylvania and West Virginia from data provided by the well operators...
June 4, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28579157/compound-mechanism-of-fatal-neck-injury-a-case-report-of-a-tiger-attack-in-a-zoo
#15
Łukasz Szleszkowski, Agata Thannhäuser, Tomasz Jurek
Fatal injuries caused by attacks by large wild cats are extremely rare in forensic medical practice in Europe. There are very few cases described in the forensic medical literature concerning incidents in zoos similar to the tiger attack on a 58-year-old male zoo employee that we present here. While preparing a runway for tigers, the man was attacked by a male Sumatran tiger. Another zoo employee was an eyewitness to the accident; in his testimony he described the sequence of events in detail. The autopsy showed the injuries typical of a tiger attack: traces of claws and canine teeth indicating that the victim of the attack was knocked down from behind, along with deep and extensive fatal wounds to the neck...
May 20, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28505102/bone-protective-effects-of-dried-plum-in-postmenopausal-women-efficacy-and-possible-mechanisms
#16
REVIEW
Bahram H Arjmandi, Sarah A Johnson, Shirin Pourafshar, Negin Navaei, Kelli S George, Shirin Hooshmand, Sheau C Chai, Neda S Akhavan
Osteoporosis is an age-related chronic disease characterized by a loss of bone mass and quality, and is associated with an increased risk of fragility fractures. Postmenopausal women are at the greatest risk of developing osteoporosis due to the cessation in ovarian hormone production, which causes accelerated bone loss. As the demographic shifts to a more aged population, a growing number of postmenopausal women will be afflicted with osteoporosis. Certain lifestyle factors, including nutrition and exercise, are known to reduce the risk of developing osteoporosis and therefore play an important role in bone health...
May 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28492130/osteogenesis-imperfecta-type-3-in-south-africa-causative-mutations-in-fkbp10
#17
Alvera Vorster, Peter Beighton, Manogari Chetty, Yasmeen Ganie, Bertram Henderson, Engela Honey, Piet Maré, David Thompson, Karen Fieggen, Denis Viljoen, Rajkumar Ramesar
BACKGROUND: A relatively high frequency of autosomal recessively inherited osteogenesis imperfecta (OI) type 3 (OI-3) is present in the indigenous black southern African population. Affected persons may be severely handicapped as a result of frequent fractures, progressive deformity of the tubular bones and spinal malalignment. OBJECTIVE: To delineate the molecular basis for the condition. METHODS: Molecular investigations were performed on 91 affected persons from seven diverse ethnolinguistic groups in this population...
April 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28470721/hox11-function-is-required-for-region-specific-fracture-repair
#18
Danielle R Rux, Jane Y Song, Kyriel M Pineault, Gurjit S Mandair, Ilea T Swinehart, Aleesa J Schlientz, Kayla N Garthus, Steve A Goldstein, Ken M Kozloff, Deneen M Wellik
The processes that govern fracture repair rely on many mechanisms that recapitulate embryonic skeletal development. Hox genes are transcription factors that perform critical patterning functions in regional domains along the axial and limb skeleton during development. Much less is known about roles for these genes in the adult skeleton. We recently reported that Hox11 genes, which function in zeugopod development (radius/ulna and tibia/fibula), are also expressed in the adult zeugopod skeleton exclusively in PDGFRα+/CD51+/LepR+ mesenchymal stem/stromal cells (MSCs)...
May 4, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28463993/periploca-forrestii-saponin-ameliorates-cia-via-suppressing-proinflammatory-cytokines-and-nuclear-factor-kappa-b-pathways
#19
Chunmei Bao, Yingqin Liu, Xin Sun, Congcong Xing, Luting Zeng, Guangchen Sun
OBJECTIVE: Periploca forrestii Schltr has been used as a Chinese folk medicine for the treatment of rheumatism, arthralgia and fractures. However, the anti-arthritic activity of Periploca forrestii saponin (PFS) and the active compound has still not been revealed. This study aimed to investigate the protective effects and mechanisms of PFS on collagen type II (CII) collagen-induced arthritis (CIA) mice. We sought to investigate whether PFS and Periplocin could regulate osteoclastogenesis, and if so, further investigation on its mechanism of action...
2017: PloS One
https://www.readbyqxmd.com/read/28443251/partial-heel-pad-avulsion-with-open-calcaneal-tuberosity-fracture-with-tendo-achilles-rupture-a-case-report
#20
Shameem Ahmed, Syed Ifthekar, R Pathan Rameez Ahmed Khan, Rahul Ranjan
INTRODUCTION: The management of heel pad avulsion injuries has been challenging because of the precarious blood supply. The difficulties get compounded when it is associated with tendo-achilles rupture and calcaneal fracture. Here, it is a description of a case with the above features managed with a unique technique. CASE REPORT: A 63-year-old woman presented to casualty with injury to right ankle after a road traffic accident. On clinical and radiological examination, there was avulsion of heel pad with calcaneal tuberosity fracture and tendo-achilles rupture...
September 2016: Journal of Orthopaedic Case Reports
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