keyword
MENU ▼
Read by QxMD icon Read
search

panton valentine

keyword
https://www.readbyqxmd.com/read/29912846/dissemination-of-the-methicillin-resistance-staphylococcus-aureus-pediatric-clone-st5-t002-iv-pvl-as-a-major-cause-of-community-associated-staphylococcal-infections-in-bedouin-children-southern-israel
#1
Assaf Rokney, Moti Baum, Shalom Ben-Shimol, Orli Sagi, Einav Anuka, Vered Agmon, David Greenberg, Lea Valinsky, Dana Danino
INTRODUCTION: Pediatric community associated methicillin resistant Staphylococcus aureus (CA-MRSA) infections are emerging worldwide. High CA-MRSA carriage rates were previously described in healthy Bedouin children. We assessed demographic, clinical and molecular characteristics of pediatric MRSA infections in southern Israel. METHODS: The Soroka University Medical Center laboratory serves the entire population of southern Israel, divided into two ethnic groups, Bedouins and Jews...
June 15, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29894277/phenotypic-and-molecular-characterization-of-methicillin-resistant-staphylococcus-aureus-clones-carrying-the-panton-valentine-leukocidin-genes-disseminating-in-iranian-hospitals
#2
Mehdi Goudarzi, Masoumeh Navidinia, Elham Beiranvand, Hossein Goudarzi
The spread of Panton-Valentine leukocidin (PVL)-carrying Staphylococcus aureus strains in both hospital and the community is a significant worldwide problem. The aim of the study was to investigate the clonal dissemination pattern of PVL-producing S. aureus strains isolated from hospitalized patients in Tehran, Iran. In this cross-sectional study, 70 PVL-carrying S. aureus strains were recovered from 240 clinical specimens and characterized by antibiotic susceptibility testing, agr typing, SCCmec typing, spa typing, multilocus sequence typing, and virulence and adhesion gene profiling...
June 12, 2018: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29880792/carriage-of-critically-important-antimicrobial-resistant-bacteria-and-zoonotic-parasites-amongst-camp-dogs-in-remote-western-australian-indigenous-communities
#3
Bertha Rusdi, Tanya Laird, Rebecca Abraham, Amanda Ash, Ian D Robertson, Shewli Mukerji, Geoffrey W Coombs, Sam Abraham, Mark A O'Dea
Camp dogs in indigenous communities in the Western Australian Kimberley Region, share the domestic environment with humans and have the potential to act as carriers of, and sentinels for, a wide range of zoonotic agents, including intestinal parasites and antimicrobial resistant bacteria. In this study, we investigated the carriage of extended-spectrum-cephalosporin-resistant (ESC-resistant) Escherichia coli, methicillin-resistant Staphylococcus aureus (MRSA) and species of hookworm and Giardia among camp dogs in remote Western Australian Aboriginal communities...
June 7, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29871957/serious-life-threatening-multifocal-infection-in-a-child-caused-by-panton-valentine-leucocidin-producing-staphylococcus-aureus-pvl-mssa
#4
Neda Irenji, Suresh Kumar Gopala Pillai, Jennifer Susan West-Jones
Groin pain is a frequently occurring complaint in presentations to the Emergency Department. Muscular sprain is often a differential diagnosis, however serious conditions such as pyomyositis should not be ignored. This case report presents a child with atraumatic right groin pain, which was initially diagnosed as a muscular sprain. The patient later re-presented out of hours to the Emergency Department with what was found to be extensive pelvic abscesses. He was subsequently found to have bilateral pneumonia and later developed a pericardial effusion and osteomyelitis of the right iliac bone, sacroiliac joint and sacrum...
June 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29868142/evolutionary-particularities-in-a-case-of-severe-pneumonia-in-children-case-report
#5
Marcela Daniela Ionescu, Nicoleta Aurelia Popescu, Georgiana Balan, Veronica Marcu, Augustina Enculescu, Lorena Vatra, Marcel Oancea, Mihaela Balgradean
Necrotizing pneumonia remains an uncommon complication of pneumonia in children, but its incidence is increasing. Pneumococcal infection is the predominant cause of severe necrotizing pneumonia in children, but methicillin resistant Staphylococcus aureus (MRSA) and Panton-Valentine leukocidin (PVL) staphylococcal infections are also important. We present the case of a four-year-old girl,with an unremarkable medical history, who was admitted in our hospital with a history of high fever, productive cough and tachypnea lasting for 10 days, progressive worsening despite empirical oral antibiotic...
March 2018: Mædica
https://www.readbyqxmd.com/read/29867940/deciphering-the-pathological-role-of-staphylococcal-%C3%AE-toxin-and-panton-valentine-leukocidin-using-a-novel-ex-vivo-human-skin-model
#6
Reuben Olayinka Olaniyi, Laura Pancotto, Luca Grimaldi, Fabio Bagnoli
Staphylococcus aureus alpha-toxin and Panton-Valentine leukocidin (PVL) have been reported to play critical roles in different animal models of skin infection. These models, however, do not completely recapitulate the human disease due to the host specificity of these toxins as well as the intrinsic anatomical and immunological differences between animals and humans. Human skin explants represent a valid alternative to animal models for studying skin infections. Herein, we developed a human skin explant wound model to study the pathogenic role of alpha-toxin and PVL; inflammatory responses elicited by these toxins; and the neutralizing ability of antibodies to mitigate skin damage...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29804839/persistent-methicillin-resistant-staphylococcus-aureus-bacteremia-owing-to-placental-abscess
#7
Naomi Maeda, Hideharu Hagiya, Tsuyoshi Takiuchi, Shinsuke Kusakabe, Tetsuo Maeda, Keigo Kimura, Sayuri Iwai, Keisuke Kawasaki, Yumiko Hori, Eiichi Morii, Yuzuru Kanakura, Tadashi Kimura, Kazunori Tomono
Staphylococcus aureus as a pathogen in human gestational membranes, a rather rare phenomenon, has recently been the focus of several researches. S. aureus forms biofilms on these membranes and potentially causes chorioamnionitis in pregnant women. We report a case of persistent methicillin-resistant S. aureus (MRSA) bacteremia owing to placental infection, causing chorioamnionitis and preterm birth. A 29-year-old Japanese woman at the 27th gestational week was diagnosed with acute promyelocytic leukemia and underwent all-trans retinoic acid therapy...
May 24, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29769634/in-vitro-generation-of-panton-valentine-leukocidin-pvl-in-clinical-methicillin-resistant-staphylococcus-aureus-mrsa-and-its-correlation-with-pvl-variant-clonal-complex-infection-type
#8
Chuanling Zhang, Yuanyu Guo, Xu Chu
The amount of Panton-Valentine leukocidin (PVL) is diverse among Staphylococcus aureus isolates from different geographical regions, and its significance in some infections is disputed. However, data concerning this information in China are limited. Fifty-one lukSF-PV+ methicillin-resistant Staphylococcus aureus (MRSA) isolates gathered from varying infections were used for PVL production using enzyme-linked immunosorbent assay, and the quantity was analyzed in correlation with PVL isoform, genetic background of the isolate, and disease category...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29746375/prevalence-and-molecular-characterization-of-s-aureus-and-mrsa-on-children-s-playgrounds
#9
Dipendra Thapaliya, Jhalka Kadariya, Mike Capuano, Haleigh Rush, Clair Yee, Mark Oet, Sapana Lohani, Tara C Smith
BACKGROUND: Staphylococcus aureus is a major public health concern due to the emergence of virulent and drug resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA). Although numerous studies have been conducted to assess the environmental contamination of S. aureus in health-care and household settings, little is known about the prevalence and epidemiology of S. aureus, including MRSA, on environmental surfaces of children's playgrounds. This study investigated the prevalence and molecular epidemiology of S...
May 9, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29736038/human-cd45-is-an-f-component-specific-receptor-for-the-staphylococcal-toxin-panton-valentine-leukocidin
#10
Angelino T Tromp, Michiel Van Gent, Pauline Abrial, Amandine Martin, Joris P Jansen, Carla J C De Haas, Kok P M Van Kessel, Bart W Bardoel, Elisabeth Kruse, Emilie Bourdonnay, Michael Boettcher, Michael T McManus, Christopher J Day, Michael P Jennings, Gérard Lina, François Vandenesch, Jos A G Van Strijp, Robert Jan Lebbink, Pieter-Jan A Haas, Thomas Henry, András N Spaan
The staphylococcal bi-component leukocidins Panton-Valentine leukocidin (PVL) and γ-haemolysin CB (HlgCB) target human phagocytes. Binding of the toxins' S-components to human complement C5a receptor 1 (C5aR1) contributes to cellular tropism and human specificity of PVL and HlgCB. To investigate the role of both leukocidins during infection, we developed a human C5aR1 knock-in (hC5aR1KI ) mouse model. HlgCB, but unexpectedly not PVL, contributed to increased bacterial loads in tissues of hC5aR1KI mice. Compared to humans, murine hC5aR1KI neutrophils showed a reduced sensitivity to PVL, which was mediated by the toxin's F-component LukF-PV...
May 7, 2018: Nature Microbiology
https://www.readbyqxmd.com/read/29735835/methicillin-resistant-staphylococcus-aureus-intracranial-abscess-an-analytical-series-and-review-on-molecular-surgical-and-medical-aspects
#11
Veena Kumari Haradara Bahubali, Priya Vijayan, Vasundhra Bhandari, Nagarathna Siddaiah, Dwarakanath Srinivas
Purpose: Intracranial abscess caused by methicillin-resistant Staphylococcus aureus (MRSA) is rare and unexplored. The aim of the present study is to examine the prevalence, clinical and molecular characteristics, treatment options and outcome of MRSA intracranial abscess over a period of 6 years. Patientsand Methods: A total of 21 patients were included in this retrospective study. The demographic and clinical details of all the patients were collected. Molecular typing including staphylococcal cassette chromosome mec typing, spa typing and polymerase chain reaction of Panton-Valentine leucocidin toxin (PVL) gene for the latter 6 isolates was performed...
January 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29734665/pediatric-methicillin-resistant-staphylococcus-aureus-osteoarticular-infections
#12
REVIEW
Ashlesha Kaushik, Helen Kest
Osteoarticular infections (OSI) are a significant cause of hospitalizations and morbidity in young children. The pediatric patient with OSI presents unique challenges in diagnosis and management due to higher morbidity, effect on growth plate with associated long-lasting sequelae, and challenges in early identification and management. Methicillin-resistant Staphylococcus aureus (MRSA), first described in the 1960s, has evolved rapidly to emerge as a predominant cause of OSI in children, and therefore empiric treatment for OSI should include an antibiotic effective against MRSA...
May 4, 2018: Microorganisms
https://www.readbyqxmd.com/read/29685228/phenotypic-and-genotypic-characteristics-of-staphylococcus-aureus-isolates-from-zoo-and-wild-animals
#13
Andrea T Feßler, Patricia Thomas, Kristin Mühldorfer, Mirjam Grobbel, Julian Brombach, Inga Eichhorn, Stefan Monecke, Ralf Ehricht, Stefan Schwarz
Antimicrobial resistance of Staphylococcus aureus is a major problem in human and veterinary medicine. The aim of this study was to characterise S. aureus isolates from wild and zoo animals mainly associated with bacterial infections. In total, 23 S. aureus isolates, including nine from wild animals and 14 from zoo animals, were obtained during routine diagnostics. All isolates were subjected to multilocus sequence typing (MLST), spa typing, macrorestriction analysis with subsequent SmaI pulsed-field gelelectrophoresis (PFGE), antimicrobial susceptibility testing and S...
May 2018: Veterinary Microbiology
https://www.readbyqxmd.com/read/29667040/management-of-superficial-and-deep-seated-staphylococcus-aureus-skin-and-soft-tissue-infections-in-sub-saharan-africa-a-post-hoc-analysis-of-the-staphnet-cohort
#14
Abraham Alabi, Theckla Kazimoto, Marthe Lebughe, Delfino Vubil, Patrick Phaku, Inacio Mandomando, Winfried V Kern, Salim Abdulla, Alexander Mellmann, Lena Peitzmann, Markus Bischoff, Georg Peters, Mathias Herrmann, Martin P Grobusch, Frieder Schaumburg, Siegbert Rieg
PURPOSE: The incidence of Staphylococcus aureus skin and soft tissue infection (SSTI) is high in sub-Saharan Africa. This is fueled by a high prevalence of Panton-Valentine leukocidin (PVL), which can be associated with necrotizing disease. The aim was to describe the clinical presentation and the treatment of SSTI in the African setting and to identify challenges in the management. METHODS: Patients (n = 319) were recruited in DR Congo (n = 56, 17.6%), Gabon (n = 89, 27...
June 2018: Infection
https://www.readbyqxmd.com/read/29662467/multilocus-sequence-typing-and-virulence-associated-gene-profile-analysis-of-staphylococcus-aureus-isolates-from-retail-ready-to-eat-food-in-china
#15
Xiaojuan Yang, Shubo Yu, Qingping Wu, Jumei Zhang, Shi Wu, Dongli Rong
The aim of this study was to characterize the subtypes and virulence profiles of 69 Staphylococcus aureus isolates obtained from retail ready-to-eat food in China. The isolates were analyzed using multilocus sequence typing (MLST) and polymerase chain reaction (PCR) analysis of important virulence factor genes, including the staphylococcal enterotoxin (SE) genes ( sea , seb , sec , sed , see , seg , seh , sei , sej ), the exfoliative toxin genes ( eta and etb ), the toxic shock syndrome toxin-1 gene ( tst ), and the Panton-Valentine leucocidin-encoding gene ( pvl )...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29657423/prevalence-and-characterization-of-panton-valentine-leukocidin-positive-staphylococcus-aureus-in-bovine-milk-in-jabalpur-district-of-madhya-pradesh-india
#16
Neeraj Shrivastava, Varsha Sharma, Arpita Shrivastav, Anju Nayak, Ajay Kumar Rai
Aim: The study aimed to investigate the Panton-Valentine leukocidin (PVL)-positive Staphylococcus aureus in bovine milk due to its public health significance. Materials and Methods: A total of 400 milk samples of bovines taken from different dairy farms and outlets of Jabalpur were screened for the S. aureus and methicillin-resistant S. aureus (MRSA). The strains were tested for the PVL gene and antimicrobial sensitivity toward 10 different classes of antimicrobial agents...
March 2018: Veterinary World
https://www.readbyqxmd.com/read/29616014/routine-whole-genome-sequencing-for-outbreak-investigations-of-staphylococcus-aureus-in-a-national-reference-center
#17
Geraldine Durand, Fabien Javerliat, Michèle Bes, Jean-Baptiste Veyrieras, Ghislaine Guigon, Nathalie Mugnier, Stéphane Schicklin, Gaël Kaneko, Emmanuelle Santiago-Allexant, Coralie Bouchiat, Patrícia Martins-Simões, Frederic Laurent, Alex Van Belkum, François Vandenesch, Anne Tristan
The French National Reference Center for Staphylococci currently uses DNA arrays and spa typing for the initial epidemiological characterization of Staphylococcus aureus strains. We here describe the use of whole-genome sequencing (WGS) to investigate retrospectively four distinct and virulent S. aureus lineages [clonal complexes (CCs): CC1, CC5, CC8, CC30] involved in hospital and community outbreaks or sporadic infections in France. We used a WGS bioinformatics pipeline based on de novo assembly (reference-free approach), single nucleotide polymorphism analysis, and on the inclusion of epidemiological markers...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29609896/pediatric-case-of-fatal-necrotizing-pneumonia-due-to-panton-valentine-leukocidin-positive-methicillin-resistant-staphylococcus-aureus-in-spain
#18
Margarita Mosquera, Laura Montero, Francisco J Pérez-Lescure, Andrés Aragón
No abstract text is available yet for this article.
March 30, 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29571899/corrigendum-to-panton-valentine-leucocidin-pvl-staphylococcus-aureus-a-position-statement-from-the-international-society-of-chemotherapy-international-journal-of-antimicrobial-agents-51-1-2018-16-25
#19
Kordo Saeed, Ian Gould, Silvano Esposito, Nusreen Ahmad-Saeed, Salman Shaheer Ahmed, Emine Alp, Abhijit M Bal, Matteo Bassetti, Eric Bonnet, Monica Chan, Geoffrey Coombs, Stephanie J Dancer, Michael Z David, Giuseppe De Simone, Matthew Dryden, Luca Guardabassi, Leif G Hanitsch, Karolin Hijazi, Renate Kruger, Andie Lee, Rasmus Leistner, Pasquale Pagliano, Elda Righi, Sylke Schneider-Burrus, Robert Leo Skov, Pierre Tattevin, Willem VanWamel, Margreet C Vos, Andreas Voss
No abstract text is available yet for this article.
March 20, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29564245/characterization-of-resistance-to-selected-antibiotics-and-panton-valentine-leukocidin-positive-staphylococcus-aureus-in-a-healthy-student-population-at-a-malaysian-university
#20
Zarizal Suhaili, Putri 'Amira Rafee, Norhidayah Mat Azis, Chew Chieng Yeo, Syafinaz Amin Nordin, Abdul Rachman Abdul Rahim, Mazen M Jamil Al-Obaidi, Mohd Nasir Mohd Desa
Introduction: This study aims to assess the antimicrobial susceptibility profiles of Staphylococcus aureus strains isolated from university students and to determine the prevalence of constitutive and inducible clindamycin resistance, the latter being able to cause therapeutic failure due to false in vitro clindamycin susceptibility. Methods: S. aureus strains were isolated from the nasal swabs of 200 health sciences students of a Malaysian university. Twelve classes of antibiotics were used to evaluate the antimicrobial susceptibility profiles with the macrolide-lincosamide-streptogramin B (MLSB ) phenotype for inducible clindamycin resistance determined by the double-diffusion test (D-test)...
March 2018: Germs
keyword
keyword
64926
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"