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https://www.readbyqxmd.com/read/29023534/bewith-a-between-within-method-to-discover-relationships-between-cancer-modules-via-integrated-analysis-of-mutual-exclusivity-co-occurrence-and-functional-interactions
#1
Phuong Dao, Yoo-Ah Kim, Damian Wojtowicz, Sanna Madan, Roded Sharan, Teresa M Przytycka
The analysis of the mutational landscape of cancer, including mutual exclusivity and co-occurrence of mutations, has been instrumental in studying the disease. We hypothesized that exploring the interplay between co-occurrence, mutual exclusivity, and functional interactions between genes will further improve our understanding of the disease and help to uncover new relations between cancer driving genes and pathways. To this end, we designed a general framework, BeWith, for identifying modules with different combinations of mutation and interaction patterns...
October 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28720128/the-utility-of-mini-clinical-evaluation-exercise-mini-cex-in-undergraduate-and-postgraduate-medical-education-protocol-for-a-systematic-review
#2
Sara Mortaz Hejri, Mohammad Jalili, Mandana Shirazi, Rasoul Masoomi, Saharnaz Nedjat, John Norcini
BACKGROUND: One of the most frequently used assessment tools that measure the trainees' performance in workplace is the mini-Clinical Evaluation Exercise (mini-CEX), in which an expert observes and rates the actual performance of trainees. Several primary studies have evaluated the effectiveness of mini-CEX by assessing its educational and psychometric properties. The objective of this BEME review is to explore, analyze, and synthesize the evidence considering the utility of the mini-CEX for assessing undergraduate and postgraduate medical trainees...
July 18, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28562193/mentoring-relationships-between-senior-physicians-and-junior-doctors-and-or-medical-students-a-thematic-review
#3
Julia Huina Sng, Yiying Pei, Ying Pin Toh, Tan Ying Peh, Shirlyn Huishan Neo, Lalit Kumar Radha Krishna
INTRODUCTION: Mentoring relationships are pivotal to the outcome of the mentoring process. This thematic review seeks to study the key aspects of mentoring relationships between senior physicians and junior doctors and/or medical students to inform efforts to improve mentoring programs. METHODS: Literature search was performed on publications across PubMed, ERIC, Cochrane Database of Systematic Reviews, OVID and ScienceDirect databases between 1 January 2000 and 31 December 2015 by three independent reviewers...
May 31, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28485686/best-evidence-medical-education-beme-review-process-redesigned-for-methodological-rigor-shorter-timeline-and-author-support
#4
Janet Corral, Sara Mortaz Hejri, Susan van Schalkwyk, Morris Gordon
No abstract text is available yet for this article.
May 9, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28261392/geriatrics-curricula-for-internal-and-family-medicine-residents-assessing-study-quality-and-learning-outcomes
#5
REVIEW
Huai Yong Cheng, Molly Davis
BACKGROUND : Prior reviews of geriatrics curricula for internal medicine (IM) and family medicine (FM) residents have not evaluated study quality or assessed learning objectives or specific IM or FM competencies. OBJECTIVE : This review of geriatrics curricula for IM and FM residents seeks to answer 3 questions: (1) What types of learning outcomes were measured? (2) How were learning outcomes measured? and (3) What was the quality of the studies? METHODS : We evaluated geriatrics curricula that reported learning objectives or competencies, teaching methods, and learning outcomes, and those that used a comparative design...
February 2017: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/28129720/effective-methods-of-teaching-and-learning-in-anatomy-as-a-basic-science-a-beme-systematic-review-beme-guide-no-44
#6
REVIEW
C Dominique Losco, William D Grant, Anthony Armson, Amanda J Meyer, Bruce F Walker
BACKGROUND: Anatomy is a subject essential to medical practice, yet time committed to teaching is on the decline, and resources required to teach anatomy is costly, particularly dissection. Advances in technology are a potential solution to the problem, while maintaining the quality of teaching required for eventual clinical application. AIM: To identify methods used to teach anatomy, including those demonstrated to enhance knowledge acquisition and retention. METHODS: PubMed, CINAHL, ERIC, Academic OneFile, ProQuest, SAGE journals and Scopus were search from the earliest entry of each database to 31 August 2015...
March 2017: Medical Teacher
https://www.readbyqxmd.com/read/27626840/tools-for-structured-team-communication-in-pre-registration-health-professions-education-a-best-evidence-medical-education-beme-review-beme-guide-no-41
#7
REVIEW
Sharon Buckley, Lucy Ambrose, Elizabeth Anderson, Jamie J Coleman, Marianne Hensman, Christine Hirsch, James Hodson, David Morley, Sarah Pittaway, Jonathan Stewart
INTRODUCTION: Calls for the inclusion of standardized protocols for information exchange into pre-registration health professions curricula have accompanied their introduction into clinical practice. In order to help clinical educators respond to these calls, we have reviewed educational interventions for pre-registration students that incorporate one or more of these ?tools for structured communication?. METHODS: Searches of 10 databases (1990?2014) were supplemented by hand searches and by citation searches (to January 2015)...
October 2016: Medical Teacher
https://www.readbyqxmd.com/read/27626710/a-beme-best-evidence-in-medical-education-review-of-the-use-of-workplace-based-assessment-in-identifying-and-remediating-underperformance-among-postgraduate-medical-trainees-beme-guide-no-43
#8
REVIEW
Aileen Barrett, Rose Galvin, Yvonne Steinert, Albert Scherpbier, Ann O'Shaughnessy, Mary Horgan, Tanya Horsley
INTRODUCTION: The extent to which workplace-based assessment (WBA) can be used as a facilitator of change among trainee doctors has not been established; this is particularly important in the case of underperforming trainees. The aim of this review is to examine the use of WBA in identifying and remediating performance among this cohort. METHODS: Following publication of a review protocol a comprehensive search of eight databases took place to identify relevant articles published prior to November 2015...
December 2016: Medical Teacher
https://www.readbyqxmd.com/read/27602533/the-failure-to-fail-underperforming-trainees-in-health-professions-education-a-beme-systematic-review-beme-guide-no-42
#9
REVIEW
Monica Yepes-Rios, Nancy Dudek, Rita Duboyce, Jerri Curtis, Rhonda J Allard, Lara Varpio
BACKGROUND: Many clinical educators feel unprepared and/or unwilling to report unsatisfactory trainee performance. This systematic review consolidates knowledge from medical, nursing, and dental literature on the experiences and perceptions of evaluators or assessors with this failure to fail phenomenon. METHODS: We searched the English language literature in CINAHL, EMBASE, and MEDLINE from January 2005 to January 2015. Qualitative and quantitative studies were included...
November 2016: Medical Teacher
https://www.readbyqxmd.com/read/27420193/a-systematic-review-of-faculty-development-initiatives-designed-to-enhance-teaching-effectiveness-a-10-year-update-beme-guide-no-40
#10
REVIEW
Yvonne Steinert, Karen Mann, Brownell Anderson, Bonnie Maureen Barnett, Angel Centeno, Laura Naismith, David Prideaux, John Spencer, Ellen Tullo, Thomas Viggiano, Helena Ward, Diana Dolmans
BACKGROUND: This review, which focused on faculty development initiatives designed to improve teaching effectiveness, synthesized findings related to intervention types, study characteristics, individual and organizational outcomes, key features, and community building. METHODS: This review included 111 studies (between 2002 and 2012) that met the review criteria. FINDINGS: Overall satisfaction with faculty development programs was high. Participants reported increased confidence, enthusiasm, and awareness of effective educational practices...
August 2016: Medical Teacher
https://www.readbyqxmd.com/read/27146438/a-beme-systematic-review-of-the-effects-of-interprofessional-education-beme-guide-no-39
#11
REVIEW
Scott Reeves, Simon Fletcher, Hugh Barr, Ivan Birch, Sylvain Boet, Nigel Davies, Angus McFadyen, Josette Rivera, Simon Kitto
BACKGROUND: Interprofessional education (IPE) aims to bring together different professionals to learn with, from, and about one another in order to collaborate more effectively in the delivery of safe, high-quality care for patients/clients. Given its potential for improving collaboration and care delivery, there have been repeated calls for the wider-scale implementation of IPE across education and clinical settings. Increasingly, a range of IPE initiatives are being implemented and evaluated which are adding to the growth of evidence for this form of education...
July 2016: Medical Teacher
https://www.readbyqxmd.com/read/27145182/which-professional-non-technical-competencies-are-most-important-to-the-success-of-graduate-veterinarians-a-best-evidence-medical-education-beme-systematic-review-beme-guide-no-38
#12
REVIEW
Martin A Cake, Melinda A Bell, Julie C Williams, Fiona J L Brown, Marshall Dozier, Susan M Rhind, Sarah Baillie
BACKGROUND: Despite the growing prominence of professional (non-technical) competencies in veterinary education, the evidence to support their importance to veterinary graduates is unclear. AIM: To summarize current evidence within the veterinary literature for the importance of professional competencies to graduate success. METHODS: A systematic search of electronic databases was conducted (CAB Abstracts, Web of Science, PubMed, PsycINFO, ERIC, Australian and British Education Index, Dissertations & Theses) from 1988 to 2015 and limited to the veterinary discipline (veterinar* term required)...
June 2016: Medical Teacher
https://www.readbyqxmd.com/read/27050026/evidence-regarding-the-utility-of-multiple-mini-interview-mmi-for-selection-to-undergraduate-health-programs-a-beme-systematic-review-beme-guide-no-37
#13
Eliot L Rees, Ashley W Hawarden, Gordon Dent, Richard Hays, Joanna Bates, Andrew B Hassell
BACKGROUND: In the 11 years since its development at McMaster University Medical School, the multiple mini-interview (MMI) has become a popular selection tool. We aimed to systematically explore, analyze and synthesize the evidence regarding MMIs for selection to undergraduate health programs. METHODS: The review protocol was peer-reviewed and prospectively registered with the Best Evidence Medical Education (BEME) collaboration. Thirteen databases were searched through 34 terms and their Boolean combinations...
May 2016: Medical Teacher
https://www.readbyqxmd.com/read/26797774/efficacy-and-safety-of-betahistine-treatment-in-patients-with-meniere-s-disease-primary-results-of-a-long-term-multicentre-double-blind-randomised-placebo-controlled-dose-defining-trial-bemed-trial
#14
RANDOMIZED CONTROLLED TRIAL
Christine Adrion, Carolin Simone Fischer, Judith Wagner, Robert Gürkov, Ulrich Mansmann, Michael Strupp
STUDY QUESTION: What is the long term efficacy of betahistine dihydrochloride on the incidence of vertigo attacks in patients with Meniere's disease, compared with placebo? METHODS: The BEMED trial is a multicentre, double blind, randomised, placebo controlled, three arm, parallel group, phase III, dose defining superiority trial conducted in 14 German tertiary referral centres (for neurology or ear, nose, and throat). Adults aged 21-80 years (mean age 56 years) with definite unilateral or bilateral Meniere's disease were recruited from March 2008 to November 2012...
January 21, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/26652745/what-do-tomorrow-s-doctors-need-to-learn-about-ecosystems-a-beme-systematic-review-beme-guide-no-36
#15
REVIEW
Sarah Catherine Walpole, David Pearson, Jonathan Coad, Stefi Barna
BACKGROUND: Human health is fundamentally determined by the health of ecosystems. Guidance is lacking about how to address the topic of ecosystems within medical education. AIMS: To determine the nature of discussions around ecosystems in the educational, medical and medical education literature. To identify learning needs of tomorrow's doctors. METHODS: A narrative synthesis approach was used. Systematic searches were completed in 14 databases...
2016: Medical Teacher
https://www.readbyqxmd.com/read/26646982/a-critical-hybrid-realist-outcomes-systematic-review-of-relationships-between-medical-education-programmes-and-communities-beme-guide-no-35
#16
REVIEW
R H Ellaway, L O'Gorman, R Strasser, D C Marsh, L Graves, P Fink, C Cervin
BACKGROUND: The relationships between medical schools and communities have long inspired and troubled medical education programmes. Successive models of community-oriented, community-based and community-engaged medical education have promised much and delivered to varying degrees. A two-armed realist systematic review was undertaken to explore and synthesize the evidence on medical school-community relationships. METHOD: One arm used standard outcomes criteria (Kirkpatrick levels), the other a realist approach seeking out the underlying contexts, mechanisms and outcomes...
2016: Medical Teacher
https://www.readbyqxmd.com/read/26610023/building-capacity-for-education-research-among-clinical-educators-in-the-health-professions-a-beme-best-evidence-medical-education-systematic-review-of-the-outcomes-of-interventions-beme-guide-no-34
#17
REVIEW
Rabia Ahmed, Ameer Farooq, Dale Storie, Lisa Hartling, Anna Oswald
BACKGROUND/PURPOSE: There is a growing desire for health professions educators to generate high-quality education research; yet, few of them encounter the training to do so. In response, health professions faculties have increasingly been devoting resources to provide members with the skills necessary for education research. The form and impact of these efforts have not been reviewed, though such a synthesis could be useful for practice. The objectives of this systematic review were to (1) identify interventions aimed at building capacity for education research among health professions clinical educators and (2) review the outcomes of these interventions...
2016: Medical Teacher
https://www.readbyqxmd.com/read/26372112/dynamics-of-career-choice-among-students-in-undergraduate-medical-courses-a-beme-systematic-review-beme-guide-no-33
#18
REVIEW
Sophie J Querido, David Vergouw, Lode Wigersma, Ronald S Batenburg, Marlies E J De Rond, Olle T J Ten Cate
INTRODUCTION: Due to the lack of a theoretically embedded overview of the recent literature on medical career decision-making, this study provides an outline of these dynamics. Since differences in educational routes to the medical degree likely affect career choice dynamics, this study focuses on medical career decision-making in educational systems with a Western European curriculum structure. METHODS: A systematic search of electronic databases (Medline, Embase) was conducted from January 2008 to November 2014...
2016: Medical Teacher
https://www.readbyqxmd.com/read/26328766/best-evidence-medical-and-health-professional-education-beme-collaboration-a-moving-spotlight
#19
Morris Gordon, Madalena Folque Patricio
Early this year, a Massachusetts Institute of Technology professor of philosophy presented a new theory of time that caught our interest. One of the key concepts that Professor Skow presented is the "moving spotlight" theory. As Skow asserts, the experiences had a year ago or 10 years ago are still just as real, they're just "inaccessible" because they are now in a different part of spacetime. This was felt to be an elegant notion to inform this 'spotlight' piece on BEME ( www.bemecollaboration.org ).
2016: Medical Teacher
https://www.readbyqxmd.com/read/26243553/impact-of-family-medicine-clerkships-in-undergraduate-medical-education-a-systematic-review
#20
REVIEW
Eralda Turkeshi, Nele R Michels, Kristin Hendrickx, Roy Remmen
OBJECTIVE: Synthesise evidence about the impact of family medicine/general practice (FM) clerkships on undergraduate medical students, teaching general/family practitioners (FPs) and/or their patients. DATA SOURCES: Medline, ERIC, PsycINFO, EMBASE and Web of Knowledge searched from 21 November to 17 December 2013. Primary, empirical, quantitative or qualitative studies, since 1990, with abstracts included. No country restrictions. Full text languages: English, French, Spanish, German, Dutch or Italian...
2015: BMJ Open
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