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https://www.readbyqxmd.com/read/28074227/heavy-metals-in-liver-and-brain-of-waterfowl-from-the-evros-delta-greece
#1
Maria Aloupi, Asimina Karagianni, Savas Kazantzidis, Triantaphyllos Akriotis
The concentrations of six heavy metals (cadmium [Cd], chromium [Cr], copper [Cu], manganese [Mn], lead [Pb], and zinc [Zn]) were determined in liver and brain of nine species of waterfowl from the Evros Delta, one of the most important wetlands in Greece, to assess metal contamination and potential risk to waterfowl. Significant differences among species were found for hepatic Cr, Cu, Pb, and Zn; the highest levels of all metals were found in liver of mute swans. Cd increased significantly with age in both organs of wigeon; some differences were also observed between males and females of the same species...
January 10, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28047649/su-g-jep1-04-characterization-of-a-high-definition-optical-patient-surface-tracking-system-across-five-installations
#2
T Smith, A Ayan, E Cochran, J Woollard, N Gupta
PURPOSE: To assess the performance of Varian's real-time, Optical Surface Monitoring System (OSMS) by measuring relative regular and irregular surface detection accuracy in 6 degrees of motion (6DoM), across multiple installations. METHODS: Varian's Intracranial SRS Package includes OSMS, which utilizes 3 HD camera/projector pods to map a patient surface, track intra-fraction motion, and gate the treatment beam if motion exceeds a threshold. To evaluate motion-detection accuracy of OSMS, we recorded shifts of a cube-shaped phantom on a single Varian TrueBeam linear accelerator as known displacements were performed incrementally across 6DoM...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28025746/gender-specific-differences-in-baseline-peak-and-delta-serum-creatinine-the-nacseld-experience
#3
Jacqueline G O'Leary, Florence Wong, K Rajender Reddy, Guadalupe Garcia-Tsao, Patrick S Kamath, Scott W Biggins, Michael B Fallon, Ram M Subramanian, B Maliakkal, Leroy Thacker, Jasmohan S Bajaj
BACKGROUND: Women have lower serum creatinine values than men for similar renal function. AIMS: We aimed to determine the differential effect of baseline, peak, and delta creatinine between genders on outcomes in infected hospitalized cirrhotic patients. METHODS: North American Consortium for the Study of End-Stage Liver Disease is a 15-center consortium of tertiary care hepatology centers prospectively enrolling infected cirrhotic inpatients...
December 26, 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27965144/mapping-of-schistosoma-mansoni-in-the-nile-delta-egypt-assessment-of-the-prevalence-by-the-circulating-cathodic-antigen-urine-assay
#4
Ayat A Haggag, Amal Rabiee, Khaled M Abd Elaziz, Albis F Gabrielli, Rehab Abdel Hay, Reda M R Ramzy
In line with WHO recommendations on elimination of schistosomiasis, accurate identification of all areas of residual transmission is a key step to design and implement measures aimed at interrupting transmission in low-endemic settings. To this purpose, we assessed the prevalence of active S. mansoni infection in five pilot governorates in the Nile Delta of Egypt by examining schoolchildren (6-15 years) using the Urine-Circulating Cathodic Antigen (Urine-CCA) cassette test; we also carried out the standard Kato-Katz (KK) thick smear, the monitoring and evaluation tool employed by Egypt's national schistosomiasis control programme...
December 11, 2016: Acta Tropica
https://www.readbyqxmd.com/read/27942006/ground-squirrel-shooting-and-potential-lead-exposure-in-breeding-avian-scavengers
#5
Garth Herring, Collin A Eagles-Smith, Mason T Wagner
Recreational ground squirrel shooting is a popular activity throughout the western United States and serves as a tool for managing ground squirrel populations in agricultural regions. Belding's ground squirrels (Spermophilus beldingi) are routinely shot in California, Nevada, and Oregon across habitats that overlap with breeding avian scavengers. Ground squirrels shot with lead (Pb)-based bullets may pose a risk to avian scavengers if they consume carcasses containing Pb fragments. To assess the potential risk to breeding avian scavengers we developed a model to estimate the number, mass, and distribution of Pb fragments in shot ground squirrels using radiographic images...
2016: PloS One
https://www.readbyqxmd.com/read/27888117/testing-assumptions-in-human-pain-models-psychophysical-differences-between-first-and-second-pain
#6
Nathanial R Eckert, Charles J Vierck, Corey B Simon, Yenisel Cruz-Almeida, Roger B Fillingim, Joseph L Riley
: Acute pain arises from activation of myelinated (A delta) and unmyelinated (C) nociceptive afferents, leading to first (A-fiber) or second (C-fiber) pain sensations. The current study sought to investigate first and second pain within glabrous and hairy skin sites in human upper limbs. Fifty healthy adults (25 male/25 female, 18-30 years old, mean = 20.5 ± 1.4 years) participated in a psychophysical study investigating electronically rated, thermal first and second pain sensations within the glabrous skin at the palm and hairy skin of the forearm...
November 22, 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27883985/a-systematic-review-of-passive-exposure-to-cannabis
#7
REVIEW
Aurélie Berthet, Mariangela De Cesare, Bernard Favrat, Frank Sporkert, Marc Augsburger, Aurélien Thomas, Christian Giroud
Passive exposure to cannabis smoke may induce effects on behavior and psychomotor skills, and have legal consequences, including the risk of being falsely considered as a cannabis user. This can become a concern, especially in occupational contexts or when driving vehicles. In order to enable a differentiation between a passive and an active exposure to cannabis and to limit the likeliness to be detected positive following passive exposure, this review identified specific biomarkers of passive exposure in urine, blood, oral fluid, hair, and sebum...
December 2016: Forensic Science International
https://www.readbyqxmd.com/read/27880976/a-novel-quantitative-microarray-antibody-capture-q-mac-assay-identifies-an-extremely-high-hdv-prevalence-amongst-hbv-infected-mongolians
#8
Xiaohua Chen, Odgerel Oidovsambuu, Ping Liu, Rosslyn Grosely, Menashe Elazar, Virginia D Winn, Benjamin Fram, Zhang Boa, Hongjie Dai, Bekhbold Dashtseren, Dahgwahdorj Yagaanbuyant, Zulkhuu Genden, Naranbaatar Dashdorj, Andreas Bungert, Naranjargal Dashdorj, Jeffrey S Glenn
: Hepatitis delta virus (HDV) causes the most severe form of human viral hepatitis. HDV requires a hepatitis B virus (HBV) co-infection to provide HDV with HBV surface antigen envelope proteins. The net effect of HDV is to make the underlying HBV disease worse, including higher rates of hepatocellular carcinoma (HCC). Accurate assessments of current HDV prevalence have been hampered by the lack of readily available and reliable quantitative assays, combined with the absence of an FDA-approved therapy...
November 23, 2016: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/27822694/occurrence-sources-and-risk-assessment-of-ocps-in-surface-sediments-from-urban-rural-and-reclamation-affected-rivers-of-the-pearl-river-delta-china
#9
Wei Wang, Junhong Bai, Min Xi, Qingqing Zhao, Guangliang Zhang, Xiaojun Wen, Rong Xiao
Sediments were collected to a depth of 20 cm from urban, rural, and reclamation-affected rivers in the Pearl River Delta of China. In total, 16 organochlorine pesticides (OCPs) were analyzed in all sediment samples, and the occurrence, possible sources, toxicity, and health risks of OCPs were evaluated to compare the contamination characteristics of OCPs in sediments among the three types of rivers. The results showed that concentrations of Σ16OCPs in sediments from the three rivers followed the order urban river > reclamation-affected river > rural river, with a mean value of 247...
November 8, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27821135/comparisons-of-volumetric-modulated-arc-therapy-vmat-quality-assurance-qa-systems-sensitivity-analysis-to-machine-errors
#10
Bin Liang, Bo Liu, Fugen Zhou, Fang-Fang Yin, Qiuwen Wu
BACKGROUND: In volumetric modulated arc therapy (VMAT), gantry angles, dose rate and the MLC positions vary with the radiation delivery. The quality assurance (QA) system should be able to catch the planning and machine errors. The aim of this study was to investigate the sensitivity of three VMAT QA systems to machine errors. METHODS: Several types of potential linac machine errors unique to VMAT delivery were simulated in sinusoidal function of gantry angle, including gantry angle itself, MLC position and linac output...
November 7, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27790156/locomotor-muscle-fatigue-does-not-alter-oxygen-uptake-kinetics-during-high-intensity-exercise
#11
James G Hopker, Giuseppe Caporaso, Andrea Azzalin, Roger Carpenter, Samuele M Marcora
The [Formula: see text] slow component ([Formula: see text]) that develops during high-intensity aerobic exercise is thought to be strongly associated with locomotor muscle fatigue. We sought to experimentally test this hypothesis by pre-fatiguing the locomotor muscles used during subsequent high-intensity cycling exercise. Over two separate visits, eight healthy male participants were asked to either perform a non-metabolically stressful 100 intermittent drop-jumps protocol (pre-fatigue condition) or rest for 33 min (control condition) according to a random and counterbalanced order...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27776309/serious-injury-prediction-algorithm-based-on-large-scale-data-and-under-triage-control
#12
Tetsuya Nishimoto, Kosuke Mukaigawa, Shigeru Tominaga, Nils Lubbe, Toru Kiuchi, Tomokazu Motomura, Hisashi Matsumoto
The present study was undertaken to construct an algorithm for an advanced automatic collision notification system based on national traffic accident data compiled by Japanese police. While US research into the development of a serious-injury prediction algorithm is based on a logistic regression algorithm using the National Automotive Sampling System/Crashworthiness Data System, the present injury prediction algorithm was based on comprehensive police data covering all accidents that occurred across Japan...
January 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/27764759/6-methoxyflavanone-attenuates-mechanical-allodynia-and-vulvodynia-in-the-streptozotocin-induced-diabetic-neuropathic-pain
#13
Shehla Akbar, Fazal Subhan, Nasiara Karim, Muhammad Shahid, Nisar Ahmad, Gowhar Ali, Wajahat Mahmood, Khwaja Fawad
BACKGROUND: Diabetic neuropathy is the most prevalent, persistent and debilitating complication of diabetes mellitus often coupled with vulvodynia that may present as an isolated symptom or as a part of constellation of other neuropathic abnormalities. OBJECTIVE: Flavonoids have selective affinity for GABA receptors and 6-methoxyflavanone (6-MeOF) is a positive allosteric modulator of GABA responses at human recombinant GABAA receptors. GABAergic and opioidergic system inhibition have been shown to facilitate neuropathic pain...
December 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27763967/functional-mri-correlates-of-resting-state-temporal-theta-and-delta-eeg-rhythms
#14
Rohit A Marawar, Hsiang J Yeh, Christopher J Carnabatu, John M Stern
PURPOSE: The EEG rhythms demonstrate changes in frequency and power with spontaneous changes in behavioral state that do not have well-understood metabolic correlates within the brain. To investigate this question and compare the temporal lobe theta and delta rhythms, resting-state functional MRI was obtained with simultaneous EEG. METHODS: Simultaneous EEG-functional MRI was recorded from 14 healthy sleep-deprived subjects in awake and drowsy states. Scalp electrodes corresponding to bilateral temporal lobes were used to calculate delta and theta band power...
January 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/27755804/quantification-of-epidermal-growth-factor-receptor-egfr-mutation-may-be-a-predictor-of-egfr-tyrosine-kinase-inhibitor-treatment-response
#15
Ha Young Park, Hyung Joo Oh, Ki-Hyun Kim, Tae-Ok Kim, Cheol-Kyu Park, Hong-Jun Shin, Jung-Hwan Lim, Yong-Soo Kwon, In-Jae Oh, Yu-Il Kim, Sung-Chul Lim, Young-Chul Kim, Yoo-Duk Choi
BACKGROUND: Epidermal growth factor receptor (EGFR) gene mutation is a reliable predictive factor for response to EGFR-tyrosine kinase inhibitors (TKIs). The quantified EGFR value may also predict response and survival within an EGFR mutated group. METHODS: We conducted a retrospective study of 836 lung cancer patients. The patient sample was divided into two groups based on the mean delta cycle threshold (∆Ct) value. EGFR mutation tests using peptide nucleic acid (PNA)-mediated clamping polymerase chain reaction (PCR) were performed...
November 2016: Thoracic Cancer
https://www.readbyqxmd.com/read/27682401/glucosylation-mediated-rolling-circle-amplification-combined-with-a-qpcr-assay-for-the-detection-of-5-hydroxymethylcytosine
#16
Di Liu, Chao Zhao, Hailin Wang
The detection of 5-hydroxymethylcytosine (5hmC), a newly recognized epigenetic mark, is essential to its functional study. Here, an efficient and simple two-step-amplification method to detect 5hmC mediated by glucosylation is reported, which combines rolling circle amplification (RCA) and a quantitative polymerase chain reaction (qPCR). In the first step RCA, the glucosylated 5hmC (5ghmC), but not 5hmC, 5-methylcytosine (5mC) or cytosine (C) bases, could directly and specifically inhibit the activity of phi29 DNA polymerase, resulting in less RCA product compared to that using C-/5mC-/5hmC-containing templates...
2016: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/27676319/risk-assessment-in-high-and-low-meld-liver-transplantation
#17
A Schlegel, M Linecker, P Kron, G Györi, M L De Oliveira, B Müllhaupt, P-A Clavien, P Dutkowski
Allocation of liver grafts triggers emotional debates, as those patients, not receiving an organ, are prone to death. We analyzed a high-Model of End-stage Liver Disease (MELD) cohort (laboratory MELD score ≥30, n = 100, median laboratory MELD score of 35; interquartile range 31-37) of liver transplant recipients at our center during the past 10 years and compared results with a low-MELD group, matched by propensity scoring for donor age, recipient age, and cold ischemia time. End points of our study were cumulative posttransplantation morbidity, cost, and survival...
September 27, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/27660608/distribution-of-response-time-cortical-and-cardiac-correlates-during-emotional-interference-in-persons-with-subclinical-psychotic-symptoms
#18
Lisa K B Holper, Alekandra Aleksandrowicz, Mario Müller, Vladeta Ajdacic-Gross, Helene Haker, Andreas J Fallgatter, Florence Hagenmuller, Wolfram Kawohl, Wulf Rössler
A psychosis phenotype can be observed below the threshold of clinical detection. The study aimed to investigate whether subclinical psychotic symptoms are associated with deficits in controlling emotional interference, and whether cortical brain and cardiac correlates of these deficits can be detected using functional near-infrared spectroscopy (fNIRS). A data set derived from a community sample was obtained from the Zurich Program for Sustainable Development of Mental Health Services. 174 subjects (mean age 29...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27593955/application-of-ssod-pi-and-pi-ssod-event-based-controllers-to-greenhouse-climatic-control
#19
A Pawlowski, M Beschi, J L Guzmán, A Visioli, M Berenguel, S Dormido
In this work, an application of the Symmetric Send-On-Delta (SSOD) event-based controllers to the inside air temperature control of the greenhouse production process is presented. The control technique analysis is split into two stages. The first stage is devoted to determine the proper controller parameters and to check the influence of the Send-On-Delta (SOD) threshold value through simulation study. At the second stage, experimental tests on the real greenhouse facilities are performed. The obtained results show that the analyzed control techniques handle the control task with desired accuracy and performance...
September 1, 2016: ISA Transactions
https://www.readbyqxmd.com/read/27508390/bacterial-loads-measured-by-the-xpert-mtb-rif-assay-as-markers-of-culture-conversion-and-bacteriological-cure-in-pulmonary-tb
#20
Shubhada Shenai, Katharina Ronacher, Stefanus Malherbe, Kim Stanley, Magdalena Kriel, Jill Winter, Thomas Peppard, Charles E Barry, Jing Wang, Lori E Dodd, Laura E Via, Clifton E Barry, Gerhard Walzl, David Alland
INTRODUCTION: Biomarkers are needed to monitor tuberculosis (TB) treatment and predict treatment outcomes. We evaluated the Xpert MTB/RIF (Xpert) assay as a biomarker for TB treatment during and at the end of the 24 weeks therapy. METHODS: Sputum from 108 HIV-negative, culture-positive pulmonary TB patients was analyzed using Xpert at time points before and during anti-TB therapy. Results were compared against culture. Direct Xpert cycle-threshold (Ct), a change in the Ct (delta Ct), or a novel "percent closing of baseline Ct deficit" (percent closing) were evaluated as classifiers of same-day and end-of-treatment culture and therapeutic outcomes...
2016: PloS One
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