Frederic Lamoth, Marcio Nucci, Ana Fernandez-Cruz, Elie Azoulay, Fanny Lanternier, Jens Bremerich, Hermann Einsele, Elizabeth Johnson, Thomas Lehrnbecher, Toine Mercier, Luciana Porto, Paul E Verweij, Lewis White, Johan Maertens, Alexandre Alanio
The (1→3)-β-D-glucan (BDG) is a component of the fungal cell wall that can be detected in serum and used as an adjunctive tool for the diagnosis of invasive mold infections (IMI) in patients with hematologic cancer or other immunosuppressive conditions. However, its use is limited by modest sensitivity/specificity, inability to differentiate between fungal pathogens and lack of detection of mucormycosis. Data about BDG performance for other relevant IMI, such as invasive fusariosis (IF) and invasive scedosporiosis/lomentosporiosis (IS) are scarce...
June 28, 2023: Medical Mycology