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Myopericytoma

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https://www.readbyqxmd.com/read/29678425/myopericytoma-of-the-base-of-the-finger-radiological-and-pathological-description-of-a-rare-benign-entity
#1
Laurent Van Camp, Jean Goubau, Ivo Van den Berghe, Koen Mermuys
A previously healthy 46-year-old woman presented with a mass lesion between the bases of the fourth and fifth fingers of the right hand. The mass had grown progressively over 2 years and started to cause practical difficulties in everyday life. Imaging depicted a hypervascular and well-circumscribed soft tissue tumor with imaging characteristics of a sarcoma. The lesion was treated surgically. The final diagnosis of the specimen upon pathology was a myopericytoma, a benign smooth-muscle cell neoplasm. Myopericytoma is a rare disease entity; however, it is important because it can mimic more ominous conditions...
April 17, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29552265/myopericytoma-myopericytomatosis-of-the-lower-extremity-in-two-young-patients-a-recently-designated-rare-soft-tissue-neoplasm
#2
Katherine Peters, Jamie T Caracciolo, Evita Henderson-Jackson, Odion Binitie
Myopericytomas are rare, slow-growing benign perivascular tumors most commonly arising within the superficial subcutaneous soft tissues of the lower extremity. They represent one of several related perivascular tumors of myoid lineage with similar morphology and shared immunohistochemical profile including positive staining for smooth muscle actin. Histologically, myopericytoma exhibit concentric, perivascular proliferation of spindled myoid cells with bland elongated nuclei and associated blood vessels. A solitary well-demarcated nodule or mass is typically referred to as myopericytoma, whereas an infiltrative multinodular lesion has more recently been termed myopericytomatosis...
February 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29530746/myopericytoma-of-the-lip-a-case-report-of-this-rare-lesion
#3
Eric Strayer, Roger Throndson, Cecilia Clement, Keith McDaniel
Myopericytomas are rare benign tumors that show a distinctive, concentric perivascular proliferation of oval to spindle-shaped myoid-appearing cells that are predominantly arranged concentrically around thin-walled vascular channels. These lesions are similar in histologic appearance to hemangiopericytomas, myofibromas, and glomus tumors. The myopericytoma is usually found in the distal extremities, but a handful of reports have shown the lesion to be present in the oral cavity. A review of the literature to date shows only 4 other reported cases of myopericytomas occurring in the lips...
February 19, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29510931/pleural-myopericytoma-a-rare-neoplasm-in-a-difficult-location
#4
Kevin Hodges, Youran Zou, Andrew Everett, Sudish Murthy, Usman Ahmad
No abstract text is available yet for this article.
February 10, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29367374/intracranial-myopericytoma-a-tumour-in-a-rare-location
#5
Rui Caetano Oliveira, Ricardo Velasco, Gonçalo Roque Santos, Olinda Rebelo
A 49-year-old female with history of headache, nausea and vomiting with some weeks of evolution, without neurological symptoms. Radiology revealed an expansive lesion near the inferior vermix and cerebellar tonsils, with heterogeneous gadolinium uptake and mass effect on the fourth ventricle, representing a probable extraventricular origin for the lesion. Pathological examination showed a proliferation of oval/spindle cell proliferation with eosinophil cytoplasm and small and monotonous nuclei, without mitoses...
January 23, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29245316/primary-malignant-myopericytoma-with-cancer-cachexia-report-of-the-first-case-and-review-of-literature
#6
REVIEW
Wenjuan Chen, Le Han, Hailin Pang, Lian Duan, Zheng Zhao
RATIONALE: Malignant myopericytoma is extremely rare, with a few cases described in the English literature. PATIENT CONCERNS: This novel study aimed to report a case of malignant myopericytoma with cancer cachexia arising in the left armpit. Also, it presented a review of the English literature regarding primary malignant myopericytoma, aiming to clarify the clinical features and potentially curative treatment. A 56-year-old male presented with an ulcerated and smelly mass involving her left armpit...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29244665/osseous-myopericytoma-simulating-a-giant-cell-tumor-of-bone-a-case-report
#7
Eric Bellinger, Ivy John, Daniel Zaccarini, Timothy A Damron
CASE: Myopericytoma is a benign perivascular myoid neoplasm that typically presents in the dermal and subcutaneous soft tissues of the distal aspect of the extremities. These types of tumor form a clinicopathological spectrum with myofibromas, angiopericytomas, angioleiomyomas, and glomus tumors. Intraosseous myopericytomas are exceptionally rare, and to our knowledge, no cases of myopericytoma involving long bones previously have been described. We present a case of myopericytoma occurring in the distal aspect of the femur of a 36-year-old man...
April 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29121378/myopericytoma-of-the-neck-originating-in-the-middle-scalene-muscle-a-case-report
#8
Mark B Chaskes, John W Bishop, Matthew Bobinski, D Gregory Farwell
We report a case of myopericytoma of the neck. A 23-year-old woman noticed a small, nontender mass in her left supraclavicular fossa. The mass had grown over a period of 5 months, prompting her to seek evaluation. On examination, no motor or sensory deficits were present. Imaging suggested that a mass had originated in the middle scalene muscle. Computed-tomography-guided core needle biopsy demonstrated a spindle-cell neoplasm with smooth-muscle differentiation. Complete surgical excision was performed. Histopathologic and immunohistochemical evaluations of the tissue sample suggested a myopericytoma...
October 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29050639/myopericytoma-of-the-tongue-base-a-case-report
#9
Stefano Rubino, Rita De Berardinis, Daniele Colombo, Alessandro De Padova
No abstract text is available yet for this article.
October 16, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28762232/morphofunctional-basis-of-the-different-types-of-angiogenesis-and-formation-of-postnatal-angiogenesis-related-secondary-structures
#10
REVIEW
L Díaz-Flores, R Gutiérrez, M P García-Suárez, F J Sáez, E Gutiérrez, F Valladares, J L Carrasco, L Díaz-Flores, J F Madrid
We review the morpho-functional basis of the different types of angiogenesis and report our observations, including the formation of angiogenesis-related secondary structures. First of all, we consider the following issues: a) conceptual differences between angiogenesis and vasculogenesis, b) incidence of angiogenesis in pre- and postnatal life, c) regions of vascular tree with angiogenic capacity, d) cells (endothelial cells, pericytes, CD34+ adventitial stromal cells of the microvasculature and inflammatory cells) and extracellular matrix components involved in angiogenesis, e) events associated with angiogenesis, f) different types of angiogenesis, including sprouting and intussusceptive angiogenesis, and other angiogenic or vascularization forms arising from endothelial precursor cells (postnatal vasculogenesis), vasculogenesis mimicry, vessel co-option and piecemeal angiogenesis...
December 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/28549043/traumatic-facial-myopericytoma-a-differential-to-consider
#11
Rachel E Aliotta, Patrick Veerkamp, Paul Durand, Melissa Piliang, Raymond Isakov
Myopericytoma is a slow-growing, benign soft tissue neoplasm that arises from perivascular smooth muscle cells. This tumor is a rare entity itself, but it is only scarcely mentioned in the literature occurring secondary to trauma. The authors report a 21-year-old male patient who presented with a pulsatile mass in the medial canthal area where he had experienced previous trauma from a car accident 1-year prior. The mass was excised and histopathology revealed myopericytoma. This clinical report adds to the limited body of evidence supporting trauma as an etiology for this rare tumor...
June 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28505006/myopericytomatosis-clinicopathologic-analysis-of-11-cases-with-molecular-identification-of-recurrent-pdgfrb-alterations-in-myopericytomatosis-and-myopericytoma
#12
Yin P Hung, Christopher D M Fletcher
Myopericytoma is a benign tumor of concentrically distributed perivascular myoid cells. Its molecular basis and relationship with myofibroma/myofibromatosis and other pericytic tumors are not fully understood. In our consultation/surgical files of over 1000 myopericytic lesions, we identified 11 cases with diffuse dermal/subcutaneous involvement by microscopic myopericytomatous nodules, a phenomenon we have termed myopericytomatosis. Myopericytomatosis affected mostly adults (female:male=8:3; median age, 37 y; range, 9 to 63 y) in the lower extremities (foot/ankle, 5; calf, 3; knee, 1; thigh, 1; neck, 1) over months to 25 years, ranging from 1...
August 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28442859/digital-myopericytoma-a-case-report-and-systematic-literature-review
#13
Alexander Morzycki, Nadim Joukhadar, Amanda Murphy, Jason Williams
A myopericytoma (MP) is an exceedingly rare perivascular tumor of unknown etiology. Given their potential for mimicry and malignancy, MP tumors pose a unique challenge for surgeons and may be overlooked on differential diagnosis. We present a case report of an otherwise healthy 33-year-old right-hand dominant male who presented to our outpatient clinic with a 2-month history of painless swelling and erythema of the pulp of his left index finger. Subsequent plain film X-ray showed near-complete bony destruction of his distal phalanx...
April 2017: Journal of Hand and Microsurgery
https://www.readbyqxmd.com/read/28438616/pericytic-tumors-of-the-kidney-a-clinicopathologic-analysis-of-17-cases
#14
MULTICENTER STUDY
Deepika Sirohi, Steven C Smith, Jonathan I Epstein, Bonnie L Balzer, Jeffry P Simko, Dana Balitzer, Jamal Benhamida, Oleksandr N Kryvenko, Nilesh S Gupta, Swetha Paluru, Isabela Werneck da Cunha, Daniel N Leal, Sean R Williamson, Mariza de Peralta-Venturina, Mahul B Amin
The pericytic (perivascular myoid cell) family of tumors is a distinctive group of mesenchymal neoplasms encountered in superficial sites and only rarely seen in viscera. The pericytic family subtends a spectrum of lesions, namely, glomus tumors and variants; myopericytoma, including myofibroma; and angioleiomyoma. In light of the contemporary classification of pericytic lesions, we identified and reviewed 17 cases of renal pericytic tumors from the files of 6 referral centers. These tumors presented over an age range of 17 to 76 years (mean 46...
June 2017: Human Pathology
https://www.readbyqxmd.com/read/28248815/recurrent-srf-rela-fusions-define-a-novel-subset-of-cellular-myofibroma-myopericytoma-a-potential-diagnostic-pitfall-with-sarcomas-with-myogenic-differentiation
#15
Cristina R Antonescu, Yun-Shao Sung, Lei Zhang, Narasimhan P Agaram, Christopher D Fletcher
Cellular myofibroblastic tumors other than desmoid-type fibromatosis are often diagnostically challenging due to their relative rarity, lack of known genetic abnormalities, and expression of muscle markers which may be confused with sarcomas with myogenic differentiation. In this study we investigate the molecular alterations of a group of cellular myofibroblastic lesions with in the myofibroma and myopericytoma spectrum for better subclassification. Two index cases were studied by paired-end RNA sequencing for potential fusion gene discovery...
May 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28219756/atrial-angioleiomyoma-with-myopericytoma-like-features-a-case-report
#16
Hussein Nassereddine, Aurélie Cazes, Constance Verdonk, Benjamin Assous, Raphael Dautry, Patrick Nataf, Michel Wassef, Lydia Deschamps
A 66-year-old female patient was referred to our hospital for resection of a right atrial mass. Four months earlier, she had suffered an acute cerebrovascular accident due to occlusion of the sylvian segment of the right middle cerebral artery from atheromatous tight stenosis in the right internal carotid artery. Later, investigations with transthoracic and transesophageal echocardiography revealed a 3.4-cm right atrial mass that was resected surgically. Microscopic evaluation revealed a well-circumscribed nodular tumor, located within the interatrial septum, and corresponding to an angioleiomyoma (ALM)...
May 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28219370/myopericytoma-occurrence-in-the-liver-and-stomach-space-imaging-performance
#17
Zhihua Chen, Wenjie Liang
BACKGROUND: Myopericytoma is a rare and usually benign tumor, which is even rarer if it occurs in the liver and stomach space. Previous reports of myopericytoma were mostly related to its pathological manifestations, while imaging reports were rare. Here, we report the computed tomography (CT), computed tomography angiography (CTA) and magnetic resonance imaging (MRI) performance for one deep myopericytoma. CASE PRESENTATION: In this study, one deep myopericytoma in the liver and stomach space is reported...
February 20, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28214470/myopericytoma-in-urinary-bladder-a-case-report
#18
Takahiro Nagai, Toshio Kamimura, Kaoru Itou, Masato Fujii, Hiromasa Tsukino, Shoichiro Mukai, Yutaka Akiyama, Hiroaki Kataoka, Toshiyuki Kamoto
BACKGROUND: Myopericytoma is reported to occur mainly in the skin and superficial soft tissue of the extremities. In contrast, occurrence in the urinary bladder is extremely rare. CASE PRESENTATION: We describe a 75-year-old Japanese man who developed a submucosal tumor at the right trigone of his bladder that led to interference with the discharge of right ureteral calculus. No invasive growth was observed by magnetic resonance imaging. Transurethral resection was successfully performed; histopathological analysis revealed perivascular proliferation of spindle-shaped to oval-shaped, cytologically bland tumor cells with eosinophilic cytoplasm...
February 19, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28088345/phenotypic-characterization-of-perivascular-myoid-cell-neoplasms-using-myosin-1b-a-newly-identified-human-pericyte-marker
#19
COMPARATIVE STUDY
Shiori Meguro, Taisuke Akamatsu, Sayomi Matsushima, Isao Kosugi, Hideya Kawasaki, Yoshifumi Arai, Satoshi Baba, Takashi Tsuchida, Yoji Shido, Takafumi Suda, Toshihide Iwashita
Our aims were to identify pericyte-specific markers for the analysis of formalin-fixed, paraffin-embedded human tissue samples, and to characterize perivascular myoid cell neoplasms phenotypically. Previously identified pericyte markers failed to distinguish pericytes from other cellular types, such as vascular smooth muscle cells (vSMCs) and fibroblasts, in immunohistochemistry analysis. However, we compared gene expression profiles between pericytes, vSMCs, and fibroblasts, and performed human skin vasculature immunohistochemistry analysis, which led to the identification of myosin 1B (MYO1B) as a novel pericyte marker...
April 2017: Human Pathology
https://www.readbyqxmd.com/read/27832007/myopericytoma-of-the-internal-auditory-canal
#20
Jacob B Hunter, Brendan P O'Connell, Woon N Chow, Kyle D Weaver, Justin M Cates, George B Wanna
No abstract text is available yet for this article.
February 2017: Otology & Neurotology
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