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https://www.readbyqxmd.com/read/28178148/monitoring-the-hemostasis-with-rotation-thromboelastometry-in-patients-with-acute-stemi-on-dual-antiplatelet-therapy-first-experiences
#1
Matej Samoš, Lucia Stančiaková, Lukáš Duraj, František Kovář, Marián Fedor, Radoslava Šimonová, Tomáš Bolek, Peter Galajda, Ján Staško, Peter Kubisz, Marián Mokáň
Rotation thromboelastometry (ROTEM) is a viscoelastometric point-of-care-test for the complex evaluation of changes in hemostasis, performed in whole blood. However, no prospective study evaluating the efficacy of the antiplatelet therapy using ROTEM was performed.Fifty-six patients (34 men, 22 women, mean age 67.75 years, and age range 34-88 years) with acute ST-elevation myocardial infarction (STEMI), treated with dual antiplatelet therapy, undergoing urgent coronary angiography and percutaneous coronary intervention (PCI) of culprit coronary lesion were included...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28169119/reperfusion-therapy-of-myocardial-infarction-in-mexico-a-challenge-for-modern-cardiology
#2
Carlos Martínez-Sánchez, Alexandra Arias-Mendoza, Héctor González-Pacheco, Diego Araiza-Garaygordobil, Luis Alfonso Marroquín-Donday, Jorge Padilla-Ibarra, Carlos Sierra-Fernández, Alfredo Altamirano-Castillo, Amada Álvarez-Sangabriel, Francisco Javier Azar-Manzur, José Luis Briseño-de la Cruz, Salvador Mendoza-García, Yigal Piña-Reyna, Marco Antonio Martínez-Ríos
Mexico has been positioned as the country with the highest mortality attributed to myocardial infarction among the members of the Organization for Economic Cooperation and Development. This rate responds to multiple factors, including a low rate of reperfusion therapy and the absence of a coordinated system of care. Primary angioplasty is the reperfusion method recommended by the guidelines, but requires multiple conditions that are not reached at all times. Early pharmacological reperfusion of the culprit coronary artery and early coronary angiography (pharmacoinvasive strategy) can be the solution to the logistical problem that primary angioplasty rises...
February 3, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/28147338/clinical-characteristics-and-improvement-of-the-guideline-based-management-of-acute-myocardial-infarction-in-china-a-national-retrospective-analysis
#3
Lechen Wang, You Zhou, Cheng Qian, Yanggan Wang
OBJECTIVE: This study is to document the clinical characteristics and improvement in management of acute myocardial infarction (AMI) in Chinese population. RESULTS: This study included 64,654 patients (23,805 patients in 2011, 40,849 patients in 2013), of which STEMI and NSTEMI account for 85.09% and 14.91%, respectively. From 2011 to 2013, significant improvement has been achieved in the recanalization rate of PCI (96.01% vs. 98.63%, P < 0.001) and in-hospital deaths (4...
January 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28144818/practice-of-st-segment-elevation-myocardial-infarction-care-in-the-netherlands-during-four-snapshot-weeks-with-the-national-cardiovascular-database-registry-for-acute-coronary-syndrome
#4
N P G Hoedemaker, M E Ten Haaf, J C Maas, P Damman, Y Appelman, J G P Tijssen, R J de Winter, A W J van 't Hof
BACKGROUND: Clinical registries provide information on the process of care and patient outcomes, with the potential to improve the quality of patient care. A large Dutch national acute coronary syndrome (ACS) registry is currently lacking. Recently, we initiated the National Cardiovascular Database Registry (NCDR) for ACS in the Netherlands. The purpose of this study was to assess the NCDR ACS registry on feasibility and data completeness during a pilot phase of four snapshot weeks...
January 31, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/28127213/components-and-determinants-of-therapeutic-delay-in-patients-with-acute-st-elevation-myocardial-infarction-a-tertiary-care-hospital-based-study
#5
Jahangir Rashid Beig, Nisar A Tramboo, Kuldeep Kumar, Irfan Yaqoob, Imran Hafeez, Fayaz A Rather, Tariq R Shah, Hilal A Rather
BACKGROUND: Delayed reperfusion is associated with worse outcomes in ST-segment elevation myocardial infarction (STEMI). This study was conducted to assess the components and determinants of therapeutic delay in STEMI patients of our state. METHODS: This study included consecutive patients of STEMI admitted to the coronary care units of two tertiary care hospitals in Srinagar, between 2012 and 2015. Various components of treatment delay including the patient's decision to delay, referral delay, transportation delay, prehospital delay, and door-to-needle time were calculated...
January 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28111177/characteristics-and-survival-determinants-in-patients-after-out-of-hospital-cardiac-arrest-in-the-era-of-24-7-coronary-intervention-facilities
#6
Josef Kroupa, Jiri Knot, Jaroslav Ulman, Frantisek Bednar, Alena Dohnalova, Zuzana Motovska
BACKGROUND: Survival rates and outcomes after out-of-hospital cardiac arrest (OHCA) remain low despite investments of time and money. The goal of this analysis was to identify variables related to survival of patients transferred to our coronary care unit (CCU) after an OHCA. METHODS: 102 consecutive OHCA patients, mean age 64.6 (SD 13.3), 70.6% men, between January, 2011 and December, 2013, who were transferred to our tertiary care CCU, were studied. RESULTS: Cardiac-cause OHCA was present in 84 patients (82...
December 24, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28100880/significant-association-of-serum-adiponectin-and-creatine-kinase-mb-levels-in-st-segment-elevation-myocardial-infarction
#7
Tomoaki Natsukawa, Norikazu Maeda, Shiro Fukuda, Masaya Yamaoka, Yuya Fujishima, Hirofumi Nagao, Fumi Sato, Hitoshi Nishizawa, Hirotaka Sawano, Yasuyuki Hayashi, Tohru Funahashi, Tatsuro Kai, Iichiro Shimomura
AIMS: Adiponectin, an adipocyte-specific secretory protein, abundantly exists in the blood stream while its concentration paradoxically decreases in obesity. Hypoadiponectinemia is one of risks of cardiovascular diseases. However, impact of serum adiponectin concentration on acute ischemic myocardial damages has not been fully clarified. The present study investigated the association of serum adiponectin and creatine kinase (CK)-MB levels in subjects with ST-segment elevation myocardial infarction (STEMI)...
January 17, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28092977/hypertension-is-associated-with-increased-mortality-in-patients-with-ischaemic-heart-disease-after-revascularization-with-percutaneous-coronary-intervention-a-report-from-scaar
#8
Ott Saluveer, Björn Redfors, Oskar Angerås, Christian Dworeck, Inger Haraldsson, Charlotta Ljungman, Petur Petursson, Jacob Odenstedt, Dan Ioanes, Peter Lundgren, Sebastian Völz, Truls Råmunddal, Bert Andersson, Elmir Omerovic, Niklas Bergh
BACKGROUND: The prognostic role of hypertension on long-term survival after percutaneous coronary intervention (PCI) is limited and inconsistent. We hypothesize that hypertension increases long-term mortality after PCI. METHODS: We analyzed data from SCAAR (Swedish Coronary Angiography and Angioplasty Registry) for all consecutive patients admitted coronary care units in Sweden between January 1995 and May 2013 and who underwent PCI due to ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI)/unstable angina (UA) or stable angina pectoris...
January 16, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28077385/impact-of-sex-and-contact-to-device-time-on-clinical-outcomes-in-acute-st-segment-elevation-myocardial-infarction-findings-from-the-national-cardiovascular-data-registry
#9
Robert O Roswell, Jordan Kunkes, Anita Y Chen, Karen Chiswell, Sohah Iqbal, Matthew T Roe, Sripal Bangalore
BACKGROUND: Emergent myocardial reperfusion via primary percutaneous coronary intervention is optimal care for patients presenting with ST-segment elevation myocardial infarction (STEMI). Delays in such interventions are associated with increases in mortality. With the shift in focus to contact-to-device (C2D) time as a new perfusion metric, this study was designed to examine how sex affects C2D time and mortality in STEMI patients. METHODS AND RESULTS: Clinical data on male and female STEMI patients were extracted and analyzed from the National Cardiovascular Data Registry from July 1, 2008 to December 31, 2014...
January 11, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28065491/meta-analysis-of-randomized-trials-on-remote-ischemic-conditioning-during-primary-percutaneous-coronary-intervention-in-patients-with-st-segment-elevation-myocardial-infarction
#10
Ayman Elbadawi, Le Dung Ha, Ahmed S Abuzaid, Gabriele Crimi, Muhammad S Azzouz
Ischemia/reperfusion injury adversely affects the final infarct size (IS) after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI). Few studies have evaluated the role of remote ischemic conditioning (RIC) in reducing ischemia/reperfusion injury. However, the results of these studies were not consistent, and an overview of overall effectiveness of this technique in patients with STEMI is lacking. We conducted this meta-analysis to evaluate the available evidence in literature regarding the application of RIC in patients with STEMI who underwent primary PCI...
December 21, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28040285/diagnostic-performance-of-a-high-sensitive-troponin-t-assay-and-a-troponin-t-point-of-care-assay-in-the-clinical-routine-of-an-emergency-department-a-clinical-cohort-study
#11
Anna Slagman, Johannes von Recum, Martin Möckel, Fabian Holert, Dirk Meyer Zum Büschenfelde, Christian Müller, Julia Searle
BACKGROUND: A point of care test (POCT) for troponin T (TnT) in the Emergency Department (ED) was compared to a high-sensitivity TnT (hsTnT) central laboratory test (CLT) to determine the influence of test system and different cut-off values on the diagnostic performance in patients with suspected acute coronary syndrome (ACS) under routine conditions. METHODS: All patients with routine TnT testing in the ED were enrolled. Only internal medicine patients without STEMI and with both troponin values were analyzed...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28034683/predictors-of-late-reperfusion-in-stemi-patients-undergoing-primary-angioplasty-impact-of-the-place-of-first-medical-contact
#12
Antoni Carol Ruiz, Josep Masip Utset, Albert Ariza Solé
INTRODUCTION AND OBJECTIVES: The benefit of primary angioplasty may be reduced if there are delays to reperfusion. Identification of the variables associated with these delays could improve health care. METHODS: Analysis of the Codi Infart registry of Catalonia and of the time to angioplasty depending on the place of first medical contact. RESULTS: In 3832 patients analyzed, first medical contact took place in primary care centers in 18% and in hospitals without a catheterization laboratory in 37%...
December 26, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/27998831/selective-use-of-contemporary-drug-eluting-stents-in-primary-angioplasty-for-st-elevation-myocardial-infarction-pooled-analysis-of-comfortable-ami-and-examination
#13
Andreas Baumbach, Dik Heg, Lorenz Räber, Miodrag Ostoijc, Salvatore Brugaletta, Julian W Strange, Thomas W Johnson, Peter Juni, Thomas Engstrøm, Patrick W Serruys, Manel Sabate, Stephan Windecker
AIMS: Selective use of DES only in patients at higher risk of MACE is common practice, particularly in healthcare systems with a large premium payable for DES. We aimed to identify subgroups of patients in which the use of BMS in primary percutaneous coronary intervention (PPCI) for STEMI can still be justified. METHODS AND RESULTS: We performed a patient-level pooled analysis of COMFORTABLE AMI and EXAMINATION comparing contemporary DES with BMS in PPCI. A risk score was applied using three parameters: lesion length >15 mm, vessel size <3 mm, and diabetes mellitus...
January 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/27931556/non-physician-health-workers-for-improving-adherence-to-medications-and-healthy-lifestyle-following-acute-coronary-syndrome-24-month-follow-up-study
#14
Krishna Kumar Sharma, Rajeev Gupta, Mukul Mathur, Vishnu Natani, Sailesh Lodha, Sanjeeb Roy, Denis Xavier
OBJECTIVE: To evaluate usefulness of non-physician health workers (NPHW) to improve adherence to medications and lifestyles following acute coronary syndrome (ACS). METHODS: We randomized 100 patients at hospital discharge following ACS to NPHW intervention (n=50) or standard care (n=50) in an open label study. NPHW was trained for interventions to improve adherence to medicines - antiplatelets, β-blockers, renin-angiotensin system (RAS) blockers and statins and healthy lifestyles...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27931539/stemi-care-in-the-elderly-does-under-treatment-reflect-appropriate-clinical-judgment-or-therapeutic-nihilism
#15
EDITORIAL
Tanush Gupta
No abstract text is available yet for this article.
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27916154/cancer-history-portends-worse-acute-and-long-term-noncardiac-but-not-cardiac-mortality-after-primary-percutaneous-coronary-intervention-for-acute-st-segment-elevation-myocardial-infarction
#16
Feilong Wang, Rajiv Gulati, Ryan J Lennon, Bradley R Lewis, Jae Park, Gurpreet S Sandhu, R Scott Wright, Amir Lerman, Joerg Herrmann
OBJECTIVE: To define the effect of a history of cancer on in-hospital and long-term mortality after primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI). PATIENTS AND METHODS: In this retrospective cohort study of 2346 patients with STEMI enrolled in the Mayo Clinic PCI registry from November 1, 2000, through October 31, 2010, we identified 261 patients (11.1%) with a history of cancer. The in-hospital and long-term outcomes (median follow-up, 6...
December 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27896906/identifying-patients-for-safe-early-hospital-discharge-following-st-elevation-myocardial-infarction
#17
Musa A Sharkawi, Andreas Filippaios, Saurabh S Dani, Sachin P Shah, Nabila Riskalla, David M Venesy, Sherif B Labib, Frederic S Resnic
OBJECTIVES: To examine whether the CADILLAC risk score is an effective method of patient stratification for early discharge following ST elevation myocardial infarction (STEMI). BACKGROUND: Patients with STEMI are typically hospitalized to monitor for serious complications such as arrhythmias, heart failure, and reinfarction. Optimal length of stay is unclear. Whether low risk patients can be safely discharged before 72 hr of hospitalization is unclear. METHODS: Patients with STEMI who underwent successful PCI were retrospectively stratified using CADILLAC risk score to low risk (n = 123) and intermediate to high risk (n = 105)...
November 29, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27844422/intracoronary-eptifibatide-during-primary-percutaneous-coronary-intervention-in-early-versus-late-presenters-with-st-segment-elevation-myocardial-infarction-a-randomized-trial
#18
Ayman Elbadawi, Gerald Gasioch, Islam Y Elgendy, Ahmed N Mahmoud, Le Dung Ha, Haitham Al Ashry, Hend Shahin, Mohamed A Hamza, Ahmed S Abuzaid, Marwan Saad
INTRODUCTION: The role of intracoronary (IC) eptifibatide in primary percutaneous coronary intervention (PPCI) for ST segment elevation myocardial infarction (STEMI) and whether time of patient presentation affects this role are unclear. We sought to evaluate the benefit of IC eptifibatide use during primary PCI in early STEMI presenters compared to late STEMI presenters. METHODS: We included 70 patients who presented with STEMI and were eligible for PPCI. On the basis of symptom-to-door time, patients were classified into two arms: early (<3 h, n = 34) vs late (≥3 h, n = 36) presenters...
December 2016: Cardiology and Therapy
https://www.readbyqxmd.com/read/27820669/marijuana-use-in-acute-coronary-syndromes
#19
Eman I Draz, Mervat M Oreby, Eman A Elsheikh, Lamia A Khedr, Salwa A Atlam
BACKGROUND: Cannabis is one of the most widely used illicit substances worldwide, and it has the highest prevalence among drugs used in Egypt. OBJECTIVES: The aims were to evaluate whether the use of cannabis is a risk factor of acute coronary heart disease in low-risk, young males and to compare the cardiac pathological changes between cannabis exposed and non-exposed ischemic patients. METHODS: This was a cross-sectional study that was performed on 138 male patients, aged ≤ 40 years, with acute myocardial infarction who were admitted to the Cardiac Care Unit at the University Hospital...
November 7, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27818120/efficacy-and-safety-of-prehospital-administration-of-unfractionated-heparin-enoxaparin-or-bivalirudin-in-patients-undergoing-primary-percutaneous-coronary-intervention-for-st-segment-elevation-myocardial-infarction-insights-from-the-orbi-registry
#20
COMPARATIVE STUDY
Vincent Auffret, Guillaume Leurent, Dominique Boulmier, Marc Bedossa, Amer Zabalawi, Jean-Philippe Hacot, Isabelle Coudert, Emmanuelle Filippi, Philippe Castellant, Antoine Rialan, Gilles Rouault, Philippe Druelles, Bertrand Boulanger, Josiane Treuil, Bertrand Avez, Marielle Le Guellec, Martine Gilard, Hervé Le Breton
BACKGROUND: Despite numerous studies in recent years, the best anticoagulant option for primary percutaneous coronary intervention (PCI) remains a matter of debate. AIMS: To compare in-hospital outcomes after prehospital administration of low-dose unfractionated heparin (UFH)±glycoprotein IIb/IIIa inhibitors (GPIs), enoxaparin±GPIs, or bivalirudin in patients undergoing primary PCI for ST-segment elevation myocardial infarction (STEMI). METHODS: A total of 1720 patients (median age 62...
December 2016: Archives of Cardiovascular Diseases
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