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https://www.readbyqxmd.com/read/28437237/proteomics-in-hypothermia-as-adjunctive-therapy-in-patients-with-st-segment-elevation-myocardial-infarction-a-chill-mi-substudy
#1
Moman A Mohammad, Marco Noc, Irene Lang, Michael Holzer, Peter Clemmensen, Ulf Jensen, Bernhard Metzler, David Erlinge
Cardiovascular and inflammatory biomarkers in therapeutic hypothermia have been studied in cardiac arrest, but data on patients with ST-segment elevation myocardial infarction (STEMI) treated with therapeutic hypothermia are currently unavailable. A multiplex proximity extension assay allowed us to measure 157 cardiovascular disease (CVD) and inflammatory disease-related biomarkers in patients from the international, multicenter, and randomized trial; CHILL-myocardial infarction (MI) and to explore the associations of cardiovascular and inflammatory biomarkers...
March 2, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28404560/statin-eligibility-and-outpatient-care-prior-to-st-segment-elevation-myocardial-infarction
#2
Michael D Miedema, Ross F Garberich, Lucas J Schnaidt, Erin Peterson, Craig Strauss, Scott Sharkey, Thomas Knickelbine, Marc C Newell, Timothy D Henry
BACKGROUND: The impact of the 2013 American College of Cardiology/American Heart Association cholesterol guidelines on statin eligibility in individuals otherwise destined to experience cardiovascular disease (CVD) events is unclear. METHODS AND RESULTS: We analyzed a prospective cohort of consecutive ST-segment elevation myocardial infarction (STEMI) patients from a regional STEMI system with data on patient demographics, low-density lipoprotein cholesterol levels, CVD risk factors, medication use, and outpatient visits over the 2 years prior to STEMI...
April 12, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28400120/impact-of-point-of-care-pre-procedure-creatinine-and-egfr-testing-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-primary-pci-the-pilot-statcreat-study
#3
Grigoris V Karamasis, James Hampton-Till, Firas Al-Janabi, Shah Mohdnazri, Michael Parker, Adam Ioannou, Rohan Jagathesan, Alagmir Kabir, Jeremy W Sayer, Nicholas M Robinson, Rajesh K Aggarwal, Gerald J Clesham, Reto A Gamma, Paul A Kelly, Kare H Tang, John R Davies, Thomas Keeble
BACKGROUND: Contrast-induced acute kidney injury (CI-AKI) is a recognised complication during primary PCI that affects short and long term prognosis. The aim of this study was to assess the impact of point-of-care (POC) pre-PPCI creatinine and eGFR testing in STEMI patients. METHODS: 160 STEMI patients (STATCREAT group) with pre-procedure POC testing of Cr and eGFR were compared with 294 consecutive retrospective STEMI patients (control group). Patients were further divided into subjects with or without pre-existing CKD...
April 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28400039/population-access-to-reperfusion-services-for-st-segment-elevation-myocardial-infarction-in-kerala-india
#4
Anoop Mathew, Jabir Abdullakutty, Placid Sebastian, Sunitha Viswanathan, Cibu Mathew, Venugopalan Nair, Padinhare P Mohanan, A George Koshy
BACKGROUND: Population access to timely reperfusion is a decisive factor in determining the success and acceptability of any regional system of ST-segment elevation myocardial infarction (STEMI) care. We sought to determine the proportion of population of the southern Indian state of Kerala having timely access to STEMI reperfusion. METHODS: We identified the STEMI reperfusion facilities available at all acute-care hospitals, in Kerala, by conducting a cross-sectional survey...
April 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28393591/presentation-management-and-mortality-after-a-first-mi-in-people-with-and-without-asthma-a-study-using-uk-minap-data
#5
Paulo Pinto, Kieran J Rothnie, Kelvin Lui, Adam Timmis, Liam Smeeth, Jennifer K Quint
Asthma has been associated with a higher incidence of myocardial infarction (MI), higher prevalence of MI risk factors and higher burden of cardiovascular diseases. However, detailed associations between the presentation and initial management at the time of MI and post-MI outcomes in people with asthma compared to the general population have not been studied. A total of 300,161 people were identified with a first MI over the period 2003-2013 in the Myocardial Ischaemia National Audit Project database, of whom 8922 (3%) had asthma...
January 1, 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28390745/effect-of-improved-door-to-balloon-time-on-clinical-outcomes-in-patients-with-st-segment-elevation-myocardial-infarction
#6
Wei-Chieh Lee, Hsiu-Yu Fang, Huang-Chung Chen, Shu-Kai Hsueh, Chien-Jen Chen, Cheng-Hsu Yang, Hon-Kan Yip, Chi-Ling Hang, Chiung-Jen Wu, Chih-Yuan Fang
OBJECTIVE: Few studies have focused on the effects of an improved door-to-balloon time on clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI). The aim of this study was to explore the effect of improving door-to-balloon time on prognosis and to identify major predictors of mortality. METHODS: From January 2005 to December 2014, 1751 patients experienced STEMI and received primary percutaneous intervention in our hospital. During a 10-year period, the patients were divided into two groups according to the time period...
March 23, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28390742/long-term-prognosis-of-atrial-fibrillation-in-st-elevation-myocardial-infarction-patients-undergoing-percutaneous-coronary-intervention
#7
Guy Topaz, Nir Flint, Arie Steinvil, Arik Finkelstein, Shmuel Banai, Gad Keren, Yacov Shacham, Lior Yankelson
BACKGROUND: Atrial fibrillation (AF) is a well-known complication in the setting of ST elevation myocardial infarction (STEMI). Data on the long-term prognostic implications of New-Onset AF (NOAF) complicating STEMI in the era of complete revascularization remains controversial. Our aim therefore was to evaluate the long-term prognosis of prior AF (pAF) and new-onset AF (NOAF) in STEMI patients undergoing percutaneous coronary intervention (PCI). METHODS: We studied 1657 consecutive STEMI patients hospitalized in the cardiac intensive care unit during 2008-2014...
March 16, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28384181/access-to-percutaneous-transluminal-coronary-angioplasty-and-30-day-mortality-in-patients-with-incident-stemi-differentials-by-educational-level-and-gender-over-11-years
#8
Laura Cacciani, Nera Agabiti, Anna Maria Bargagli, Marina Davoli
BACKGROUND: Socioeconomic status and gender are associated with access to cardiac procedures and mortality after AMI, also in countries with universal health care systems. Our objective was to evaluate the association and trends of educational level or gender and the following outcomes: 1) access to PTCA; 2) 30-day mortality. METHODS: We conducted an observational study based on 14,013 subjects aged 35-74 years, residing in Rome in 2001, and hospitalised for incident STEMI within 2012 in the Lazio region...
2017: PloS One
https://www.readbyqxmd.com/read/28367010/prehospital-delay-and-time-to-reperfusion-therapy-in-st-elevation-myocardial-infarction
#9
Linsha George, Lakshmi Ramamoorthy, Santhosh Satheesh, Rama Prakasha Saya, D K S Subrahmanyam
BACKGROUND: Despite efforts aimed at reducing the prehospital delay and treatment delay, a considerable proportion of patients with ST elevation myocardial infarction (STEMI) present late and receive the reperfusion therapy after unacceptably long time periods. This study aimed at finding out the patients' decision delay, prehospital delay, door-to-electrocardiography (ECG), door-to-needle, and door-to-primary percutaneous coronary intervention (PCI) times and their determinants among STEMI patients...
April 2017: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/28345538/current-trends-for-st-segment-elevation-myocardial-infarction-during-the-past-5-years-in-rural-areas-of-china-s-liaoning-province-a-multicenter-study
#10
Guang-Xiao Li, Bo Zhou, Guo-Xian Qi, Bo Zhang, Da-Ming Jiang, Gui-Mei Wu, Bing Ma, Peng Zhang, Qiong-Rui Zhao, Juan Li, Ying Li, Jing-Pu Shi
BACKGROUND: Since 2010, two versions of National Guidelines aimed at promoting the management of ST-segment elevation myocardial infarction (STEMI) have been formulated by the Chinese Society of Cardiology. However, little is known about the changes in clinical characteristics, management, and in-hospital outcomes in rural areas. METHODS: In the present multicenter, cross-sectional study, participants were enrolled from rural hospitals located in Liaoning province in Northeast China, during two different periods (from June 2009 to June 2010 and from January 2015 to December 2015)...
April 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28341086/recurrent-priapism-gone-wrong-st-elevation-myocardial-infarction-and-cardiogenic-shock-after-penile-corporal-phenylephrine-irrigation
#11
S Tyler Constantine, Anand Gopalsami, Gregg Helland
BACKGROUND: Recurrent priapism secondary to sickle cell trait in an African-American male has been reported in the literature. A common treatment for these low-flow priapism cases is aspiration and injection of the corpus cavernosum with a sympathomimetic agent. We report a rare complication not described previously in the literature of ST-elevation myocardial infarction (STEMI) and cardiogenic shock in a 29-year-old male with sickle cell trait undergoing a routine detumescence procedure...
March 21, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28320312/the-effect-of-an-electronic-cognitive-aid-on-the-management-of-st-elevation-myocardial-infarction-during-caesarean-section-a-prospective-randomised-simulation-study
#12
Michael St Pierre, Bjoern Luetcke, Dieter Strembski, Christopher Schmitt, Georg Breuer
BACKGROUND: Cognitive aids have come to be viewed as promising tools in the management of perioperative critical events. The majority of published simulation studies have focussed on perioperative crises that are characterised by time pressure, rare occurrence, or complex management steps (e.g., cardiac arrest emergencies, management of the difficult airway). At present, there is limited information on the usefulness of cognitive aids in critical situations with moderate time pressure and complexity...
March 20, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28296641/root-cause-analysis-of-deaths-in-st-segment-elevation-myocardial-infarctions-treated-with-primary-pci-what-can-we-do-better
#13
Fredy El Sakr, Mohamad Kenaan, Daniel Menees, Milan Seth, Hitinder S Gurm
OBJECTIVE: Recent data demonstrate that mortality of patients with ST-elevation myocardial infarction (STEMI) has not changed despite dramatic reduction in door-to-balloon times. Identifying potential areas in care that can be further optimized to decrease mortality remains a priority. METHODS: We performed a root cause analysis of all patients who died following primary percutaneous coronary intervention (PCI) during index hospitalization from 2008 to 2013 at the University of Michigan...
May 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28286090/surgical-revascularisation-in-the-early-phase-of-st-segment-elevation-myocardial-infarction-haemodynamic-status-is-more-important-than-the-timing-of-the-operation
#14
Vilem Rohn, Tomas Grus, Jan Belohlavek, Jan Horak
BACKGROUND: Surgical revascularisation in patients with acute myocardial infarction with ST-Segment Elevation (STEMI) is usually considered as a second choice when direct angioplasty/stent fails. However, improvements in surgical technique and postoperative care may justify coronary artery bypass grafting (CABG) in STEMI. METHODS: This was a retrospective analysis of prospectively gathered data of 135 patients with acute STEMI, treated with CABG in our department from February 2008 to December 2012...
February 28, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28283469/timely-reperfusion-in-stroke-and-myocardial-infarction-is-not-correlated-an-opportunity-for-better-coordination-of-acute-care
#15
Kori Sauser Zachrison, Deborah A Levine, Gregg C Fonarow, Deepak L Bhatt, Margueritte Cox, Phillip Schulte, Eric E Smith, Robert E Suter, Ying Xian, Lee H Schwamm
BACKGROUND: Timely reperfusion is critical in acute ischemic stroke (AIS) and ST-segment-elevation myocardial infarction (STEMI). The degree to which hospital performance is correlated on emergent STEMI and AIS care is unknown. Primary objective of this study was to determine whether there was a positive correlation between hospital performance on door-to-balloon (D2B) time for STEMI and door-to-needle (DTN) time for AIS, with and without controlling for patient and hospital differences...
March 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28273293/a-system-of-care-for-patients-with-st-segment-elevation-myocardial-infarction-in-india-the-tamil-nadu-st-segment-elevation-myocardial-infarction-program
#16
Thomas Alexander, Ajit S Mullasari, George Joseph, Kumaresan Kannan, Ganesh Veerasekar, Suma M Victor, Colby Ayers, Viji Samuel Thomson, Vijayakumar Subban, Justin Paul Gnanaraj, Jagat Narula, Dharam J Kumbhani, Brahmajee K Nallamothu
Importance: Challenges to improving ST-segment elevation myocardial infarction (STEMI) care are formidable in low- to middle-income countries because of several system-level factors. Objective: To examine access to reperfusion and percutaneous coronary intervention (PCI) during STEMI using a hub-and-spoke model. Design, Setting, and Participants: This multicenter, prospective, observational study of a quality improvement program studied 2420 patients 20 years or older with symptoms or signs consistent with STEMI at primary care clinics, small hospitals, and PCI hospitals in the southern state of Tamil Nadu in India...
March 8, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28256327/st-segment-elevation-myocardial-infarction-systems-of-care-an-urgent-need-for-policies-to-co-ordinate-care-in-order-to-decrease-in-hospital-mortality
#17
Ali Osama Malik, Oliver Abela, Gayle Allenback, Subodh Devabhaktuni, Calvin Lui, Aditi Singh, Jimmy Diep, Takashi Yamashita, Ji Won Yoo, Sanjay Malhotra, Chowdhury Ahsan
BACKGROUND: Regional trends for ST-segment elevation myocardial infarction (STEMI) treatment is not known in the state of Nevada. HYPOTHESIS: Great disparity exists for treatment for STEMI in different geographical areas of Nevada. There is a great potential to improve treatment and outcomes of STEMI patients in the State of Nevada. METHODS: Admissions to non-federal hospitals in the state of Nevada, using 2011 to 2013 discharge data from the Nevada State Inpatient Data Base (acquired from Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality), were analyzed...
February 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28256299/assessment-of-coronary-care-management-and-hospital-mortality-from-st-segment-elevation-myocardial-infarction-in-the-kazakhstan-population-data-from-2012-to-2015
#18
Zhanar Akimbaeva, Zhumagali Ismailov, Aikan A Akanov, Ričardas Radišauskas, Žilvinas Padaiga
OBJECTIVE: The aim of this study was to assess and evaluate factors related to coronary care management and hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) hospitalized in the Kazakhstan County and city hospitals in which percutaneous coronary intervention (PCI) was performed during the period of 2012-2015. MATERIALS AND METHODS: A total of 22,176 adult patients (18> years) with acute STEMI were hospitalized from January 2012 to December 2015...
February 20, 2017: Medicina
https://www.readbyqxmd.com/read/28242589/intravenous-beta-blocker-therapy-in-st-segment-elevation-myocardial-infarction-treated-with-primary-percutaneous-coronary-intervention-is-not-associated-with-benefit-regarding-short-term-mortality-a-swedish-nationwide-observational-study
#19
Moman A Mohammad, Pontus Andell, Sasha Koul, Liyew Desta, Tomas Jernberg, Elmir Omerovic, Jonas Spaak, Ole Fröbert, Jens Jensen, Thomas Engstrøm, Claes Hofman-Bang, Hans Persson, David Erlinge
AIMS: To investigate the impact of intravenous (IV) beta-blocker therapy on short-term mortality and other in-hospital events in patients with ST-segment elevation myocardial infarction (STEMI) treated with dual antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PCI). METHODS AND RESULTS: Using the nationwide Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART) registry, we identified all patients with STEMI undergoing PCI between 2006 and 2013...
February 28, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28216220/stemi-care-in-poland-and-the-united-states-both-have-some-distance-yet-to-travel
#20
EDITORIAL
Peter B Berger, Molly Perini, Lance B Becker
No abstract text is available yet for this article.
March 13, 2017: JACC. Cardiovascular Interventions
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