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https://www.readbyqxmd.com/read/28338567/bevacizumab-therapy-for-pilomyxoid-astrocytoma
#1
Ryan D Metts, Walter Bartynski, Cynthia T Welsh, Stephen Kinsman, Amy-Lee Bredlau
Pilomyxoid astrocytoma is a rare tumor of the central nervous system generally found in young children near the hypothalamus. Herein, we report a 19-month-old female infant with a pilomyxoid astrocytoma, who underwent surgery as well as carboplatin and vincristine chemotherapy in an attempt to delay radiation therapy to the brain. Magnetic resonance imaging revealed that the tumor had increased in tumor volume on therapy. Chemotherapy with carboplatin and vincristine was stopped and bevacizumab therapy (10 mg/kg every other week) was initiated...
March 23, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28337175/effects-of-chronic-acth-excess-on-human-adrenal-cortex
#2
REVIEW
Xavier Bertagna
Chronic ACTH excess leads to chronic cortisol excess, without escape phenomenon, resulting in Cushing's syndrome. Excess adrenal androgens also occur: in females, they will overcompensate the gonadotrophic loss, inducing high testosterone; in males, they will not compensate it, inducing low testosterone. Chronic ACTH excess leads to chronic adrenal mineralocorticoid excess and low aldosterone levels: after an acute rise, aldosterone plasma levels resume low values after a few days when ACTH is prolonged. Two other mineralocorticoids in man, cortisol and 11 deoxycorticosterone (DOC), at the zona fasciculata, will not escape the long-term effect of chronic ACTH excess and their secretion rates will remain elevated in parallel...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28335100/is-the-reinitiation-of-antiplatelet-agents-safe-at-1-week-after-gastric-endoscopic-submucosal-dissection-assessment-of-bleeding-risk-using-the-forrest-classification
#3
Jong Yeul Lee, Chan Gyoo Kim, Soo-Jeong Cho, Young-Il Kim, Il Ju Choi
Background/Aims: Delayed bleeding after gastric endoscopic submucosal dissection (ESD) commonly occurs within 3 days, but it may also occur after 1 week following ESD, especially in antiplatelet agent users. We evaluated the risk of delayed bleeding in post-ESD ulcers using the Forrest classification. Methods: Registry data on the Forrest classification of post-ESD ulcers (n=371) at 1 week or 2 weeks after ESD were retrospectively evaluated. The Forrest classification was categorized into two groups: increased risk (Forrest Ia to IIc) or low risk (Forrest III)...
March 24, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28332031/how-do-energy-stores-and-changes-in-these-affect-departure-decisions-by-migratory-birds-a-critical-view-on-stopover-ecology-studies-and-some-future-perspectives
#4
REVIEW
Heiko Schmaljohann, Cas Eikenaar
In birds, accumulating energy is far slower than spending energy during flight. During migration, birds spend, therefore, most of the time at stopover refueling energy used during the previous flight. This elucidates why current energy stores and actual rate of accumulating energy are likely crucial factors influencing bird's decision when to resume migration in addition to other intrinsic (sex, age) and extrinsic (predation, weather) factors modulating the decision within the innate migration program. After first summarizing how energy stores and stopover durations are generally determined, we critically review that high-energy stores and low rates of accumulating energy were significantly related to high departure probabilities in several bird groups...
March 22, 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/28332018/seasonal-loss-and-resumption-of-circadian-rhythms-in-hibernating-arctic-ground-squirrels
#5
Cory T Williams, Maya Radonich, Brian M Barnes, C Loren Buck
Circadian clocks are near universal among organisms and play a key role in coordinating physiological and metabolic functions to anticipate or coincide with predictable daily changes in the physical and social environment. However, whether circadian rhythms persist and are functionally important during hibernation in all mammals is currently unclear. We examined whether circadian rhythms of body temperature (T b) persist during multi-day, steady-state torpor and investigated the association between timing of animal emergence, exposure to light, and resumption of activity and T b rhythms in free-living and captive male arctic ground squirrels...
March 22, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/28330336/postpartum-modern-contraceptive-use-and-associated-factors-in-northern-ethiopia
#6
Teklehaymanot Huluf Abraha, Alemayehu Shimeka Teferra, Abebaw Addis Gelagay
OBJECTIVES: Postpartum period is a critical period to address high unmet needs of family planning and to reduce the risks of closely spaced pregnancies. However, contraception during extended postpartum period has given less emphasis concerning contraceptive practice in Ethiopia. Therefore, this study was aimed to assess postpartum modern contraceptive use and associated factors among postpartum women in Northern Ethiopia. METHODS: A community based cross sectional study was done from March to April, 2015...
March 20, 2017: Epidemiology and Health
https://www.readbyqxmd.com/read/28327067/common-carotid-artery-ligation-to-minimize-blood-loss-during-oral-and-maxillofacial-surgery
#7
Alice E Goodman, Andrew R Goodman
Oral and maxillofacial surgery in veterinary medicine carries the risk of severe hemorrhage due to the great vascular supply of the head. Temporary hemostasis can be achieved with the application of pressure or hemostatic agents, but more definitive treatment may be needed to ensure bleeding will not resume once the patient is awake and normotensive. (1 , 2) Actively bleeding vessels encountered during maxillofacial surgery may be inaccessible, and vessels may recoil into bone, sometimes preventing definitive ligation...
September 2016: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28325458/chronic-subdural-hematoma-icu-management
#8
REVIEW
Jeremy T Ragland, Kiwon Lee
Patients with cSDH presenting with new or worsening neurological deficits, especially if they are debilitating and adversely affecting quality of life require urgent medical and surgical attention. Neurological and neurosurgical critical care team need to stabilize the patient by reversing any underlying coagulopathy states in order to prevent further hematoma expansion.In the event of brain herniation and presumed ICP elevation and CPP compromise, step-wise ICP management should be instituted promptly.Seizure prophylaxis treatment is reasonable...
April 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28323591/treatment-and-monitoring-of-central-serous-chorioretinopathy-in-pilots
#9
Ari Shinojima, Ryusaburo Mori, Kyoko Fujita, Mitsuko Yuzawa
BACKGROUND: Central serous chorioretinopathy (CSC), which has the characteristics of a serous retinal detachment (SRD) in the macular area, affects mostly men in the 30- to 50-yr age range. Some patients have persistent SRD, which may cause retinal thinning and photoreceptor impairment. CSC symptoms are gradual vision loss and/or metamorphopsia. Some commercial airline pilots are concerned about CSC symptoms, which can disqualify them from flying for months and can also reoccur. Thus, careful monitoring and treatment of CSC are critical for pilots, especially those with chronic or recurrent CSC...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28322552/one-step-fabrication-of-a-microfluidic-device-with-an-integrated-membrane-and-embedded-reagents-by-multimaterial-3d-printing
#10
Feng Li, Petr Smejkal, Niall P Macdonald, Rosanne M Guijt, Michael C Breadmore
One of the largest impediments in the development of microfluidic-based smart sensing systems is the manufacturability of integrated, complex devices. Here, we propose multimaterial 3D printing for the fabrication of such devices in a single step. A microfluidic device containing an integrated porous membrane and embedded liquid reagents was made by 3D printing and applied for the analysis of nitrate from soil. The manufacture of the integrated, sealed device was realised as a single print within 30 min. The body of the device was printed in transparent acrylonitrile butadiene styrene (ABS), and contained a 400 μm wide structure printed from a commercially available composite filament...
March 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28321807/laparoscopic-anterior-gastropexy-for-type-iii-iv-hiatal-hernia-in-elderly-patients
#11
Shigeyoshi Higashi, Kiyokazu Nakajima, Koji Tanaka, Yasuhiro Miyazaki, Tomoki Makino, Tsuyoshi Takahashi, Yukinori Kurokawa, Makoto Yamasaki, Shuji Takiguchi, Masaki Mori, Yuichiro Doki
INTRODUCTION: Large esophageal hiatal hernias occur most commonly in elderly patients with comorbidities, in whom even an elective surgery cannot be performed without high risks. Although fundoplication is recommended for esophageal hiatal hernia repair, we prefer not to limit our options to fundoplication, as obstruction is a frequent main complaint. We favor an anterior gastropexy approach instead to perform anti-reflux surgery and prevent recurrent protrusion and torsion of the incarcerated organ with minimal risk...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28319621/resolution-of-psoriatic-lesions-on-the-gingiva-and-hard-palate-following-administration-of-adalimumab-for-cutaneous-psoriasis
#12
John K Brooks, Justin W Kleinman, Charlotte E Modly, John R Basile
We report the case of a 51-year-old man who presented with an atypical inflammatory response of the gingiva and hard palate that was concomitant with widespread cutaneous psoriasis. The patient had discontinued taking adalimumab 6 months prior to presentation, having achieved satisfactory management of his cutaneous lesions; however, he resumed 2 days prior to presentation due to recurrent disease. A gingival biopsy was consistent with oral psoriasis. At a 2-month follow-up, dramatic resolution of oral involvement was evident and the cutaneous psoriatic plaques were greatly reduced in size...
February 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28318426/r%C3%A3-sum%C3%A3-s
#13
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Global Health Promotion
https://www.readbyqxmd.com/read/28315698/worldwide-demography-of-centenarians
#14
REVIEW
Jean-Marie Robine, Sarah Cubaynes
The global number of centenarians should strongly increase during the 21 st century. According to the Population Division of the United Nations it should reach more than 25 million people in 2100. To better understand the dynamics of the emergence and growth of the centenarian population, we focused on four European countries having long chronological series and high quality data about centenarians, Denmark, France, Sweden, and Switzerland, and Japan which has had the highest life expectancy at birth for several years...
March 15, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/28300600/ethanolic-extracts-of-inula-viscosa-salix-alba-and-quercus-calliprinos-negatively-affect-the-development-of-the-entomopathogenic-nematode-heterorhabditis-bacteriophora-a-model-to-compare-gastro-intestinal-nematodes-developmental-effect
#15
Velayudhan Satheeja Santhi, Liora Salame, Levana Dvash, Hussein Muklada, Hassan Azaizeh, Raghda Mreny, Safaa Awwad, Alex Markovics, Serge Yan Landau, Itamar Glazer
Heterorhabditis bacteriophora can represent a model system for herbal medication against gastro-intestinal strongylid parasites in determining the recovery and development due to their unique parasitic infectious cycle. The fact that plant extracts impair nematode development is known but their differential impact on stages of the life cycle of H. bacteriophora has never been investigated. We examined the developmental stages resumed from eggs, young juveniles (J1-3), infective juveniles (IJs), young and adult hermaphrodites of H...
March 11, 2017: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/28300049/type-i-monteggia-with-ipsilateral-fracture-of-distal-radius-epiphyseal-injury-a-rare-case-report
#16
Gaurav Mundada, Sohael Mohammed Khan, Shraddha K Singhania, Varun Gupta, Pradeep K Singh, Saherish Khan
Simultaneous Monteggia injuries of the elbow and ipsilateral fracture distal radius with epiphyseal injury both bone are a unique case. A unique case of a Type I Monteggia fracture equivalent with ipsilateral fracture distal radius with epiphyseal injury (Salter-Harris Type II) in a child is reported. We describe the management of this unique fracture and discuss the possible mechanism of injury. We have highlighted a rare combination of injuries. Early recognition and prompt surgical intervention can lead to a satisfactory outcome even in these complex injuries...
January 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28300048/cardiovascular-responses-to-millet-pounding-activity-among-women-in-a-rural-community-in-northeastern-nigeria
#17
Adetoyeje Y Oyeyemi, Fati Jajimaji, Adewale L Oyeyemi, Abdul-Hameed A Jabbo
BACKGROUND: Pounding food items in a wooden mortal is a common home chore in many communities in African and Asian countries. However, no empirical data exist on energy expenditure during this activity, and whether the activity can be considered a light, moderate, or vigorous intensity physical activity is unknown. PURPOSE: This study was aimed at gaining insights into energy expenditure during millet pounding through cardiovascular responses to millet pounding activity, and to explore possible differences in response between women who pound millet as their occupation (habitual millet pounders) and those who pound millet only for their own home cooking but not as a job (nonhabitual pounders)...
January 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28300047/knowledge-attitude-and-experience-of-cervical-cancer-and-screening-among-sub-saharan-african-female-students-in-a-uk-university
#18
Faith Sopuruchukwu Ogbonna
BACKGROUND: Cervical cancer is one of the major diseases that affect women of child bearing age. Its main cause is the human papilloma virus; although, other associated factors have been evidenced to increase its risk. Pap-smear screening and vaccination which has been shown to be successful in reducing the incidence and prevalence of the disease in developed countries, has been neglected in developing countries due to lack of knowledge, misconceptions, and cultural beliefs. MATERIALS AND METHODS: A cross-sectional study involving only female Sub-Saharan Africa (SSA) students in a UK university setting...
January 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28300046/final-year-nursing-students-in-nigeria-how-knowledgeable-and-prepared-are-they-to-offer-medical-care-to-patients-with-chronic-kidney-disease
#19
Chimezie Godswill Okwuonu, Hannah Sylvanus Kanu, Ojeh-Oziegbe Odigie
BACKGROUND: Nurses play an important role in the management of chronic kidney disease (CKD) patients at primary, secondary, and tertiary levels of care. In other to perform their functions, it is pertinent that they have a good understanding of kidney functions and CKD. We do not know if the current educational curriculum prepares them adequately for this role. AIM: To assess the knowledge level of kidney functions and diseases among final year nursing students in Abia State Nigeria...
January 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28300045/-nature-cures-an-alternative-herbal-formulation-as-a-denture-cleanser
#20
R Sushma, Tanuja Tanaji Sathe, Anand Farias, Pronob Kumar Sanyal, Shashi Kiran
BACKGROUND: Candida albicans is one of the microorganisms which harbor the oral cavity, especially in elderly. However, the incidence of existence of this increases in patients using removable dental prosthesis. There is therefore a need to test the anticandidal efficacy of these cost-effective, easily available products to be used as routine denture cleansers. AIM AND OBJECTIVES: (1) To evaluate antifungal properties of triphala churna on the heat cure denture base material...
January 2017: Annals of African Medicine
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