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https://www.readbyqxmd.com/read/29238575/non-traumatic-isolated-medial-cuneiform-fracture-a-unique-mechanism-of-a-rare-injury
#1
Gabriella Paisan, Steven Magister, Andrew Bridgforth, Seth Yarboro
We report a case of a 23-year-old woman who sustained a stress fracture to the medial cuneiform. Isolated medial cuneiform fractures are extremely rare with less than 10 cases reported in the literature. The patient initially presented to an urgent care facility complaining of right midfoot pain that occurred while running. Radiographs obtained at the time showed no acute abnormality and the patient was told to resume normal activities. Several weeks later, she presented to urgent care again after exercising, this time unable to bear weight and with swelling and ecchymoses of the right foot...
2017: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29238470/the-effects-of-activated-omental-extract-on-nuclear-and-cytoplasmic-in-vitro-maturation-of-rat-oocytes
#2
Fakhroddin Mesbah, Aris Donic Pracha, Tahereh Talaei-Khozani, Soghra Bahmanpour
Objective: The role of growth factors, including vascular endothelial growth factor of activated omentum on mitosis is clearly known, though not on all the aspects of in vitro oocyte maturation. This study was designed to assess the effect of activated-omental extract (AOE) on in vitro maturation (IVM) of rat cumulus-oocyte complexes (COCs). Materials and Methods: In this experimental study, the COCs were incubated in Ham's F-10 supplemented with either 20% AOE, 20% fetal bovine serum (FBS) or serum-free media...
December 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29236085/performance-evaluation-of-bluetooth-low-energy-a-systematic-review
#3
REVIEW
Jacopo Tosi, Fabrizio Taffoni, Marco Santacatterina, Roberto Sannino, Domenico Formica
Small, compact and embedded sensors are a pervasive technology in everyday life for a wide number of applications (e.g., wearable devices, domotics, e-health systems, etc.). In this context, wireless transmission plays a key role, and among available solutions, Bluetooth Low Energy (BLE) is gaining more and more popularity. BLE merges together good performance, low-energy consumption and widespread diffusion. The aim of this work is to review the main methodologies adopted to investigate BLE performance. The first part of this review is an in-depth description of the protocol, highlighting the main characteristics and implementation details...
December 13, 2017: Sensors
https://www.readbyqxmd.com/read/29234107/bulky-lesion-bypass-requires-dpo4-binding-in-distinct-conformations
#4
Pramodha S Liyanage, Alice R Walker, Alfonso Brenlla, G Andrés Cisneros, Louis J Romano, David Rueda
Translesion DNA synthesis is an essential process that helps resume DNA replication at forks stalled near bulky adducts on the DNA. Benzo[a]pyrene (B[a]P) is a polycyclic aromatic hydrocarbon (PAH) that can be metabolically activated to benzo[a]pyrene diol epoxide (BPDE), which then can react with DNA to form carcinogenic DNA adducts. Here, we have used single-molecule florescence resonance energy transfer (smFRET) experiments, classical molecular dynamics simulations, and nucleotide incorporation assays to investigate the mechanism by which the model Y-family polymerase, Dpo4, bypasses a (+)-cis-B[a]P-N 2-dG adduct in DNA...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29231149/radiopharmaceuticals-labelled-with-copper-radionuclides-clinical-results-in-human-beings
#5
Giulia Anna Follacchio, Maria Silvia De Feo, Francesco Monteleone, Giuseppe De Vincentis, Mauro Liberatore
Positron emission tomography (PET) is an instrumental diagnostic modality based on the representation (by images or numeric parameters) of the spatial and temporal distribution of molecules labelled with positron-emitting radionuclides. PET makes it possible to study biochemical processes underlying the function of several organs, providing information otherwise achievable only with bioptic assessment. PET has been developed around the positron-emitting radioisotopes of biologically important elements such as carbon, oxygen and nitrogen (11C, 15O, 13N), which enable PET imaging to identify the biodistribution of a wide range of small molecules...
December 11, 2017: Current Radiopharmaceuticals
https://www.readbyqxmd.com/read/29228114/effects-of-exportin-1-on-nuclear-transport-and-meiotic-resumption-in-porcine-full-grown-and-growing-oocytes
#6
Asuka Onuma, Yoshie A Fujioka, Wataru Fujii, Koji Sugiura, Kunihiko Naito
Exportin 1 (XPO1) is a nuclear transport receptor involved in the nuclear export of majority proteins in somatic cells. In mammalian oocytes, however, only the presence of XPO1 has been reported at mRNA and protein levels, and the definitive functions of XPO1 and its effects on the meiotic maturation of oocytes have never been directly examined. In the present study, the expression state and the nuclear-export function of porcine XPO1 were analyzed in porcine oocytes. In addition, we investigated the effects of the overexpression and inhibition of XPO1 on meiotic regulation in full-grown and growing oocytes by mRNA injection and inhibitor treatment...
December 8, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29224458/corticosteroids-for-the-management-of-immune-related-adverse-events-in-patients-receiving-checkpoint-inhibitors
#7
Kiersten J Williams, Dennis W Grauer, David W Henry, Michelle L Rockey
Introduction Due to enhanced T-cell activity, immune checkpoint inhibitors cause immune-related adverse effects. Corticosteroids are the mainstay of immune-related adverse effect management but the optimal strategy has not been determined, putting patients at risk for steroid-related adverse effects and potentially decreased efficacy of immunotherapy. This study aims to characterize the use of corticosteroids for the management of immune-related adverse effect. Methods and materials A retrospective, single-center evaluation of patients receiving checkpoint inhibitors was conducted...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29222735/delayed-perforation-after-endoscopic-submucosal-dissection-treated-successfully-by-temporary-stent-placement
#8
Masami Omae, Magnus Konradsson, Francisco Baldaque-Silva
A 71-year-old male patient with a long-segment (C10M12) Barrett's esophagus harboring multifocal high-grade dysplasia was referred to our clinic. After a multidisciplinary team conference and the patient's informed consent, an endoscopic submucosal dissection (ESD) was performed with resection of 4/5 of the esophageal circumference along 12 cm, without any complications during or immediately after the procedure. In the day after the ESD, the patient presented suddenly with dyspnea and subcutaneous emphysema in the neck and chest...
December 8, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29222608/the-impact-of-subsidized-private-health-insurance-and-health-facility-upgrades-on-healthcare-utilization-and-spending-in-rural-nigeria
#9
Emily Gustafsson-Wright, Gosia Popławska, Zlata Tanović, Jacques van der Gaag
This paper analyzes the quantitative impact of an intervention that provides subsidized low-cost private health insurance together with health facility upgrades in Nigeria. The evaluation, which measures impact on healthcare utilization and spending, is based on a quasi-experimental design and utilizes three population-based household surveys over a 4-year period. After 4 years, the intervention increased healthcare use by 25.2 percentage points in the treatment area overall and by 17.7 percentage points among the insured...
December 8, 2017: International Journal of Health Economics and Management
https://www.readbyqxmd.com/read/29222031/evaluation-of-the-effect-of-mesotherapy-in-the-management-of-back-pain-in-police-working-dog
#10
João Ca Alves, Ana Mmp Dos Santos, Ângelo Dp Fernandes
OBJECTIVE: To evaluate the feasibility and effectiveness of mesotherapy in dogs compared with a positive control group. STUDY DESIGN: Experimental, randomized, blinded study. ANIMALS: Fifteen working police dogs with chronic back pain. METHODS: Animals were divided randomly into control (CG; n = 5) and treatment groups (TG; n = 10). A combination of 140 mg lidocaine, 15 mg dexamethasone and 20 mg thiocolchicoside was administered to group TG along with a 70-day course of a placebo, administered as if it was carprofen...
August 19, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29221300/comparison-of-continuous-compression-with-regular-ventilations-versus-30-2-compressions-ventilations-strategy-during-mechanical-cardiopulmonary-resuscitation-in-a-porcine-model-of-cardiac-arrest
#11
Zhengfei Yang, Qingyu Liu, Guanghui Zheng, Zhifeng Liu, Longyuan Jiang, Qing Lin, Rui Chen, Wanchun Tang
Background: A compression-ventilation (C:V) ratio of 30:2 is recommended for adult cardiopulmonary resuscitation (CPR) by the current American Heart Association (AHA) guidelines. However, continuous chest compression (CCC) is an alternative strategy for CPR that minimizes interruption especially when an advanced airway exists. In this study, we investigated the effects of 30:2 mechanical CPR when compared with CCC in combination with regular ventilation in a porcine model. Methods: Sixteen male domestic pigs weighing 39±2 kg were utilized...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29219885/displaced-clavicle-fractures-in-cyclists-return-to-athletic-activity-after-anteroinferior-plate-fixation
#12
Ven Denise J C van der, Tim K Timmers, Ivo A M J Broeders, Olden G D J van
BACKGROUND: One of the most commonly observed injuries in cycling is fracture of the clavicle. Nevertheless, there is limited literature available on clinical outcomes after plate fixation of clavicle fractures in cyclists, rehabilitation protocols, and the time to return to sports. PURPOSE: The aim of this study was to evaluate the functional outcome, complications, and return to athletic activity at short-term follow-up after surgical repair. STUDY DESIGN: Case series...
December 1, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29219536/infrared-quantum-information
#13
Daniel Carney, Laurent Chaurette, Dominik Neuenfeld, Gordon Walter Semenoff
We discuss information-theoretic properties of low-energy photons and gravitons in the S matrix. Given an incoming n-particle momentum eigenstate, we demonstrate that unobserved soft photons decohere nearly all outgoing momentum superpositions of charged particles, while the universality of gravity implies that soft gravitons decohere nearly all outgoing momentum superpositions of all the hard particles. Using this decoherence, we compute the entanglement entropy of the soft bosons and show that it is infrared-finite when the leading divergences are resummed in the manner of Bloch and Nordsieck...
November 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29219398/threshold-and-jet-radius-joint-resummation-for-single-inclusive-jet-production
#14
Xiaohui Liu, Sven-Olaf Moch, Felix Ringer
We present the first threshold and jet radius jointly resummed cross section for single-inclusive hadronic jet production. We work at next-to-leading logarithmic accuracy and our framework allows for a systematic extension beyond the currently achieved precision. Long-standing numerical issues are overcome by performing the resummation directly in momentum space within soft collinear effective theory. We present the first numerical results for the LHC and observe an improved description of the available data...
November 24, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29219281/impact-on-sexual-function-of-surgical-treatment-in-rectal-cancer
#15
Pedro Costa, João M Cardoso, Hugo Louro, Jorge Dias, Luís Costa, Raquel Rodrigues, Paulo Espiridião, Jorge Maciel, Luís Ferraz
INTRODUCTION: The development of new surgical techniques and medical devices, like therapeutical multimodal approaches has allowed for better outcomes on patients with rectal cancer (RCa). Owing to that, an increased awareness and investment towards better outcomes regarding patients' sexual and urinary function has been recently observed. AIM: Evaluate and characterize the sexual dysfunction of patients submitted to surgical treatment for RCa. MATERIALS AND METHODS: An observational retrospective study including all male patients who underwent a surgical treatment for RCa between January 2011 December 2014 (n=43) was performed, complemented with an inquiry questionnaire to every patient about its sexual habits and level of function before and after surgery...
December 11, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29218126/a-pilot-study-comparing-hysteroscopic-adhesiolysis-by-conventional-resectoscope-versus-mini-resectoscope
#16
Kallol Kumar Roy, Archana Lingampally, Yamini Kansal, Juhi Bharti, Sunesh Kumar, Perumal Vanamail, Seema Singhal, Jyoti Meena
Objectives: To compare the feasibility and efficacy of the mini-resectoscope with the conventional resectoscope in terms of the operative, menstrual, and reproductive outcome in hysteroscopic adhesiolysis in infertile women. Methods: We conducted a parallel prospective randomized study at All India Institute of Medical Sciences, New Delhi. A total of 60 patients underwent hysteroscopic adhesiolysis using either conventional resectoscope (n = 30) or mini-resectoscope (n = 30)...
November 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/29217685/scale-free-amplitude-modulation-of-neuronal-oscillations-tracks-comprehension-of-accelerated-speech
#17
Ana Filipa Teixeira Borges, Anne-Lise Giraud, Huibert D Mansvelder, Klaus Linkenkaer-Hansen
Speech comprehension is preserved up to a three-fold acceleration but rapidly deteriorates at higher speeds. Current models posit that perceptual resilience to accelerated speech is limited by the brain's ability to parse speech into syllabic units using delta/theta oscillations. Here, we ask whether the involvement of neuronal oscillations in processing accelerated speech also relates to their scale-free amplitude modulation as indexed by the strength of long-range temporal correlations (LRTC). We recorded magnetoencephalography (MEG) while 24 human subjects (12 females) listened to radio news uttered at different comprehensible rates, at a mostly unintelligible rate, and at this same speed interleaved with silence gaps...
December 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29214826/effects-of-a-sedentary-intervention-on-cognitive-function
#18
Meghan K Edwards, Paul D Loprinzi
PURPOSE: To examine the effects of a free-living, sedentary-inducing intervention on cognitive function. DESIGN: Randomized controlled, parallel group intervention. SETTING: University campus. PARTICIPANTS: Thirty-three young adults (n = 23 intervention; n = 10 control). MEASURES: The intervention group was asked to eliminate all exercise and minimize steps to ≤5000 steps/day for 1 week, whereas the control group was asked to continue normal physical activity (PA) levels for 1 week...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29214023/assessment-and-clinical-management-of-bone-disease-in-adults-with-eating-disorders-a-review
#19
REVIEW
Anne Drabkin, Micol S Rothman, Elizabeth Wassenaar, Margherita Mascolo, Philip S Mehler
Aim: To review current medical literature regarding the causes and clinical management options for low bone mineral density (BMD) in adult patients with eating disorders. Background: Low bone mineral density is a common complication of eating disorders with potentially lifelong debilitating consequences. Definitive, rigorous guidelines for screening, prevention and management are lacking. This article intends to provide a review of the literature to date and current options for prevention and treatment...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/29213286/survival-of-five-strains-of-shiga-toxigenic-escherichia-coli-in-a-sausage-fermentation-model-and-subsequent-sensitivity-to-stress-from-gastric-acid-and-intestinal-fluid
#20
Tone Mari Rode, Anette McLeod, Ingrid Måge, Even Heir, Lars Axelsson, Askild L Holck
The ability of foodborne pathogens to exhibit adaptive responses to stressful conditions in foods may enhance their survival when passing through the gastrointestinal system. We aimed to determine whether Escherichia coli surviving stresses encountered during a model dry-fermented sausage (DFS) production process exhibit enhanced tolerance and survival in an in vitro gastrointestinal model. Salami sausage batters spiked with five E. coli isolates, including enterohaemorrhagic E. coli strains isolated from different DFS outbreaks, were fermented in a model DFS process (20°C, 21 days)...
2017: International Journal of Microbiology
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