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https://www.readbyqxmd.com/read/29031058/trimethoprim-degradation-by-fenton-and-fe-ii-activated-persulfate-processes
#1
Shizong Wang, Jianlong Wang
Trimethoprim is a pollutant ubiquitous in the environment due to its extensive application, and it cannot be effectively removed by conventional wastewater treatment processes. In this study, the Fenton and the Fe(II)-activated persulfate processes were employed to degrade trimethoprim in an aqueous solution. The results showed that the concentration of persulfate, H2O2 and Fe(II) a had significant influence on the degradation of trimethoprim in both processes. De-ionized water spiked with trimethoprim resulted in the complete degradation of trimethoprim (0...
October 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/29029338/to-include-or-not-to-include-the-impact-of-gene-filtering-on-species-tree-estimation-methods
#2
Erin K Molloy, Tandy Warnow
With the increasing availability of whole genome data, many species trees are being constructed from hundreds to thousands of loci. Although concatenation analysis using maximum likelihood is a standard approach for estimating species trees, it does not account for gene tree heterogeneity, which can occur due to many biological processes, such as incomplete lineage sorting. Coalescent species tree estimation methods, many of which are statistically consistent in the presence of incomplete lineage sorting, include Bayesian methods that co-estimate the gene trees and the species tree, summary methods that compute the species tree by combining estimated gene trees, and site-based methods that infer the species tree from site patterns in the alignments of different loci...
September 15, 2017: Systematic Biology
https://www.readbyqxmd.com/read/29029333/more-than-counting-an-intraindividual-variability-approach-to-categorical-repeated-measures
#3
Rachel E Koffer, Nilam Ram, David M Almeida
Objectives: Age-related differences in daily experiences are often described using summaries of categorical repeated measures, including typologies of stressors, activities, social partners, and coping strategies. This paper illustrates how an intraindividual variability (IIV) framework can be used to extract additional meaning from categorical IIV data. Method: Using 8-occasion categorical data on daily stressors from the National Study of Daily Experiences (N = 1,499, MAge = 46...
September 27, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29029296/the-british-society-for-rheumatology-guideline-for-the-management-of-systemic-lupus-erythematosus-in-adults-executive-summary
#4
Caroline Gordon, Maame-Boatemaa Amissah-Arthur, Mary Gayed, Sue Brown, Ian N Bruce, David D'Cruz, Benjamin Empson, Bridget Griffiths, David Jayne, Munther Khamashta, Liz Lightstone, Peter Norton, Yvonne Norton, Karen Schreiber, David Isenberg
No abstract text is available yet for this article.
October 6, 2017: Rheumatology
https://www.readbyqxmd.com/read/29029294/cardiovascular-events-in-anti-neutrophil-cytoplasmic-antibody-associated-vasculitis-a-meta-analysis-of-observational-studies
#5
Eline Houben, Erik L Penne, Alexandre E Voskuyl, Joost W van der Heijden, René H J Otten, Maarten Boers, Tiny Hoekstra
Objectives: Several chronic inflammatory diseases are associated with cardiovascular disease, but the risk in ANCA-associated vasculitis is poorly quantified. The aim of the present study was to review the evidence for an increased cardiovascular risk, including ischaemic heart disease, cerebrovascular accidents and peripheral arterial disease, in patients with ANCA-associated vasculitis. Methods: A comprehensive systematic review was conducted in accordance with guidelines of preferred reporting items for systematic reviews and meta-analyses...
September 18, 2017: Rheumatology
https://www.readbyqxmd.com/read/29029172/dnasp-6-dna-sequence-polymorphism-analysis-of-large-datasets
#6
Julio Rozas, Albert Ferrer-Mata, Juan Carlos Sánchez-DelBarrio, Sara Guirao-Rico, Pablo Librado, Sebastián E Ramos-Onsins, Alejandro Sánchez-Gracia
We present version 6 of the DnaSP (DNA Sequence Polymorphism) software, a new version of the popular tool for performing exhaustive population genetic analyses on multiple sequence alignments. This major upgrade incorporates novel functionalities to analyse large datasets, such as those generated by high-throughput sequencing (HTS) technologies. Among other features, DnaSP 6 implements: i) modules for reading and analysing data from genomic partitioning methods, such as RADseq or hybrid enrichment approaches, ii) faster methods scalable for HTS data, and iii) summary statistics for the analysis of multi-locus population genetics data...
September 18, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29029162/aberrant-global-and-jagged-mediated-notch-signaling-disrupts-segregation-between-wt1-expressing-and-steroidogenic-tissues-in-zebrafish
#7
Chih-Wei Chou, Jamie Lin, Yun-Jin Jiang, Yi-Wen Liu
Though the zebrafish interrenal tissue has been used as a model for steroidogenesis and genesis of the adrenal gland, its specification and morphogenesis is still largely unclear. In this study, we explored how the WT1-expressing cells are segregated from the SF-1-expressing steroidogenic cells in the zebrafish model. The interrenal tissue precursors expressing ff1b, the equivalent of mammalian SF-1, are derived from wt1-expressing pronephric primordia in the zebrafish embryo. Through histochemistry and in situ hybridization, we demonstrated that the size of functionally-differentiated interrenal tissue was significantly increased upon a global inhibition of the Notch signaling pathway, which was accompanied by a disrupted segregation between the wt1- and ff1b-expressing cells...
September 29, 2017: Endocrinology
https://www.readbyqxmd.com/read/29028981/tofacitinib-in-patients-with-ulcerative-colitis-health-related-quality-of-life-in-phase%C3%A2-3-randomized-controlled-induction-and-maintenance-studies
#8
Julian Panés, Séverine Vermeire, James O Lindsay, Bruce E Sands, Chinyu Su, Gary Friedman, Haiying Zhang, Aaron Yarlas, Martha Bayliss, Stephen Maher, Joseph C Cappelleri, Andrew G Bushmakin, David T Rubin
Background and Aims: Tofacitinib is an oral, small molecule JAK inhibitor that is being investigated for UC. We evaluated healthrelated quality of life [HRQoL] in tofacitinib UC Phase 3 studies. Methods: Patients ≥18 years old in OCTAVE Induction 1 [N=598] and 2 [N=541] with moderately to severely active UC were randomized [1:4] to placebo or tofacitinib 10mg twice daily [BID] for 8 weeks. Subsequently, OCTAVE Sustain re-randomized [1:1:1] clinical responders [N=593] from induction studies to placebo, tofacitinib 5 or 10mg BID for 52 weeks...
September 27, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29028803/scale-of-body-connection-a-multi-sample-construct-validation-study
#9
Cynthia J Price, Elaine Adams Thompson, Sunny Chieh Cheng
The Scale of Body Connection (SBC) was created to address the need for a self-report measure to examine body awareness and bodily dissociation in mind-body research. Developed in the U.S.A., it has been translated into many languages and tested for validity of scale translation. The burgeoning of mind-body research and the widespread use of the SBC scale underscored the need for critical assessment of the instrument's measurement properties. Thus, a broader evaluation of the SBC was designed using large samples from eight international, cross-sectional studies drawn from community (i...
2017: PloS One
https://www.readbyqxmd.com/read/29028791/is-diacerein-an-alternative-for-the-treatment-of-osteoarthritis
#10
Anselmo Alegría, Sebastián Irarrázaval
INTRODUCTION: Among the possibilities for the management of osteoarthritis, different pharmacological alternatives have been proposed, being diacerein one of them due to its anti-inflammatory effect. However, diacerein clinical utility is not clear. METHODS: To answer this question, we used Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others...
October 12, 2017: Medwave
https://www.readbyqxmd.com/read/29028753/can-economic-model-transparency-improve-provider-interpretation-of-cost-effectiveness-analysis-evaluating-tradeoffs-presented-by-the-second-panel-on-cost-effectiveness-in-health-and-medicine
#11
William V Padula, Robert Brett McQueen, Peter J Pronovost
The Second Panel on Cost-Effectiveness in Health and Medicine convened on December 7, 2016 at the National Academy of Medicine to disseminate their recommendations for conduct, methodological practices, and reporting of cost-effectiveness analyses (CEAs). Following its summary, panel proceedings included lengthy discussions including the field's struggle to disseminate findings efficiently through peer-reviewed literature to target audiences. With editors of several medical and outcomes research journals in attendance, there was consensus that findings of cost-effectiveness analyses do not effectively reach other researchers or health care providers...
November 2017: Medical Care
https://www.readbyqxmd.com/read/29028618/one-single-standard-substance-for-the-simultaneous-determination-of-17-triterpenes-in-ganoderma-lingzhi-and-its-related-species-using-high-performance-liquid-chromatography
#12
Wei Liu, Jingsong Zhang, Wei Han, Yanfang Liu, Jie Feng, Chuanhong Tang, Na Feng, Qingjiu Tang
Due to the difficulty and high cost for the preparation of triterpenes, one single standard for the simultaneous determination of multi-components (SSDMC) with high performance liquid chromatography (HPLC) is an advanced solution for multi-component analysis. Experiments were carried out to investigate the feasibility of SSDMC for the analysis of Ganoderma triterpenes, with external standard method (ESM) compared, and the samples of Ganoderma were classified by the content of Ganoderma triterpenes. The analysis was performed by using a Fortis Speed Core-C18 column (150mm×4...
October 6, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29028445/return-to-sport-specific-performance-after-primary-anterior-cruciate-ligament-reconstruction-a-systematic-review
#13
Nicholas G Mohtadi, Denise S Chan
BACKGROUND: Physicians counseling athletes on the prognosis of sport-specific performance outcomes after anterior cruciate ligament reconstruction (ACLR) depend on the published literature. However, critical appraisal of the validity and biases in these studies is required to understand how ACLR affects an athlete's ability to return to sport, the athlete's sport-specific performance, and his or her ability to achieve preinjury levels of performance. PURPOSE: This review identifies the published prognostic studies evaluating sport-specific performance outcomes after ACLR...
October 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29028363/summary-gliding-through-the-golden-years-gracefully
#14
A Vinik
No abstract text is available yet for this article.
September 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29028165/executive-summary-of-the-6th-meeting-of-the-who-expert-working-group-of-the-gisrs-for-surveillance-of-antiviral-susceptibility
#15
(no author information available yet)
No abstract text is available yet for this article.
October 13, 2017: Relevé épidémiologique Hebdomadaire
https://www.readbyqxmd.com/read/29028164/executive-summary-of-the-9th-meeting-of-the-who-working-group-rt-pcr-for-the-detection-and-subtyping-of-influenza-viruses
#16
(no author information available yet)
No abstract text is available yet for this article.
October 13, 2017: Relevé épidémiologique Hebdomadaire
https://www.readbyqxmd.com/read/29028138/2d-ruddlesden-popper-perovskites-for-optoelectronics
#17
REVIEW
Yani Chen, Yong Sun, Jiajun Peng, Junhui Tang, Kaibo Zheng, Ziqi Liang
Conventional 3D organic-inorganic halide perovskites have recently undergone unprecedented rapid development. Yet, their inherent instabilities over moisture, light, and heat remain a crucial challenge prior to the realization of commercialization. By contrast, the emerging 2D Ruddlesden-Popper-type perovskites have recently attracted increasing attention owing to their great environmental stability. However, the research of 2D perovskites is just in their infancy. In comparison to 3D analogues, they are natural quantum wells with a much larger exciton binding energy...
October 13, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29027898/surgery-versus-antibiotics-for-uncomplicated-appendicitis-which-would-a-medical-student-want
#18
Alison R Althans, Pierre Tamer, Justin T Brady, Emily Steinhagen, Vanessa P Ho
BACKGROUND: Recent data suggest that treatment of acute, uncomplicated appendicitis (AUA) with antibiotics is as effective as surgery. A 2015 study indicated that more than 50% of patients would choose antibiotic therapy. Medical students represent a unique population of potential patients with greater medical knowledge than the general public and possibly less bias than practicing physicians. Therefore, we aimed to evaluate what the MEDICAL STUDENT'S treatment choice for AUA would be and what factors influence these decisions...
October 13, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29027853/intraoperative-test-stimulation-versus-stereotactic-accuracy-as-a-surgical-end-point-a-comparison-of-essential-tremor-outcomes-after-ventral-intermediate-nucleus-deep-brain-stimulation
#19
Tsinsue Chen, Zaman Mirzadeh, Kristina M Chapple, Margaret Lambert, Virgilio G H Evidente, Guillermo Moguel-Cobos, Srivadee Oravivattanakul, Padma Mahant, Francisco A Ponce
OBJECTIVE Ventral intermediate nucleus deep brain stimulation (DBS) for essential tremor is traditionally performed with intraoperative test stimulation and conscious sedation, without general anesthesia (GA). Recently, the authors reported retrospective data on 17 patients undergoing DBS after induction of GA with standardized anatomical coordinates on T1-weighted MRI sequences used for indirect targeting. Here, they compare prospectively collected data from essential tremor patients undergoing DBS both with GA and without GA (non-GA)...
October 13, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29027830/occurrence-types-properties-and-interactions-of-phenolic-compounds-with-other-food-constituents-in-oil-bearing-plants
#20
Muhammad H Alu'datt, Taha Rababah, Mohammad N Alhamad, Ghaid J Al-Rabadi, Carole C Tranchant, Ali Almajwal, Stan Kubow, Inteaz Alli
Phenolic phytochemicals have become of interest due to their therapeutic potential, particularly with regards to their anti-cancer, anti-inflammatory, hypolipidemic, and hypoglycemic properties. An evolving area of research involving phenolics in foods and their products pertains to the functional, biological, and nutritional consequences resulting from the binding between certain phenolic compounds and the macronutrient and micronutrient constituents of foods. The goal of this review is to provide a summary of studies investigating endogenous phenolic interactions with major components in food systems, including carbohydrates, proteins, lipids, minerals and vitamins, with a focus on the phenolic compounds and nutrients in oil-bearing plants...
October 13, 2017: Critical Reviews in Food Science and Nutrition
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