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https://www.readbyqxmd.com/read/28551932/-hormone-replacement-therapy-after-gynecological-malignancies
#1
REVIEW
Nadav Michaan, Dan Grisaru
Treatment of gynecological malignancies can cause an abrupt onset of menopausal symptoms along with associated long term morbidity. Hormone replacement therapy (HRT) is the most effective treatment to alleviate these symptoms but the safety of HRT among gynecologic oncology patients remains controversial. We conducted a review of the published literature on the risk of recurrent disease among gynecologic cancer patients using HRT. Our research revealed a shortage of prospective, randomized trials on this important subject...
March 2017: Harefuah
https://www.readbyqxmd.com/read/28551864/highlights-from-the-scientific-and-educational-abstracts-presented-at-the-aser-2016-annual-scientific-meeting-and-postgraduate-course
#2
Morris Hayim, Sudheer Balakrishnan
The annual meeting of the American Society of Radiology (ASER) took place in San Francisco, California on September 14 through September 17, 2016. Attendees represented the USA as well as international emergency radiology communities, including those from academic, private practice, and teleradiology settings. There were several "members in training" in attendance as well. The meeting again featured the "Trauma Head to Toe" 2-day didactic course, highlighting various important topics on imaging of traumatic injuries...
May 27, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28551724/the-rate-of-adherence-to-urate-lowering-therapy-and-associated-factors-in-chinese-gout-patients-a-cross-sectional-study
#3
Rulan Yin, Haixia Cao, Ting Fu, Qiuxiang Zhang, Lijuan Zhang, Liren Li, Zhifeng Gu
The aim of this study was to assess adherence rate and predictors of non-adherence with urate-lowering therapy (ULT) in Chinese gout patients. A cross-sectional study was administered to 125 gout patients using the Compliance Questionnaire on Rheumatology (CQR) for adherence to ULT. Patients were asked to complete the Treatment Satisfaction Questionnaire for Medication version II, Health Assessment Questionnaire, Confidence in Gout Treatment Questionnaire, Gout Knowledge Questionnaire, Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, and 36-Item Short Form Health Survey...
May 27, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28551706/oral-administration-of-ethanolamine-glycerophospholipid-containing-a-high-level-of-plasmalogen-improves-memory-impairment-in-amyloid-%C3%AE-infused-rats
#4
Shinji Yamashita, Michio Hashimoto, Abdul Md Haque, Kiyotaka Nakagawa, Mikio Kinoshita, Osamu Shido, Teruo Miyazawa
Ethanolamine plasmalogen (PlsEtn), a major phospholipid in neuronal membranes [60-90 mol% of ethanolamine glycerophospholipid (EtnGpl)], is specifically decreased in brains from patients with Alzheimer's disease (AD). The present study investigated how PlsEtn administration affects cognitive deficits and lipid composition in an animal model of AD. AD model rats were infused with amyloid-β (Aβ) into the cerebral ventricle and divided into three groups. Control, Egg, and Ascidian groups were then orally administered vehicle, egg yolk EtnGpl (260 μmol as EtnGpl/kg BW/day; 10 μmol as PlsEtn/kg BW/day), or ascidian viscera EtnGpl (260 μmol as EtnGpl/kg BW/day; 209 μmol as PlsEtn/kg BW/day), respectively...
May 27, 2017: Lipids
https://www.readbyqxmd.com/read/28551694/-association-of-the-meaning-of-life-with-satisfaction-the-occurrence-of-subjective-complaints-and-the-family-s-economic-status-in-the-population-of-lower-secondary-school-students
#5
Dorota Zawadzka, Magdalena Stalmach, Anna Oblacińska, Izabela Tabak
INTRODUCTION: Feeling of meaning in life is extremely crucial factor of mental health. The lack of it can result in various disorders. Many authors, especially those connected with current of humanistic psychology underline the teenagers' life sense. THE AIM: The aim of the paper was to examine the level of satisfaction with life, the frequency of psychosomatic complaints by junior high school students as well as the estimation of economical status of family and the analysis of meaning in life with above mentioned factors...
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/28551671/sarcoidosis-under-dendritic-cell-vaccination-immunotherapy-in-long-term-responding-patients-with-metastatic-melanoma
#6
Ugur Uslu, Michael Erdmann, Stefan Schliep, Jan Dörrie, Niels Schaft, Gerold Schuler, Beatrice Schuler-Thurner
Sarcoidosis, a chronic inflammatory disorder, results from increased immune responses. Its development can be triggered in patients under immunotherapy, as activation of the immune system in these patients is desired. Since 1997, 249 patients with metastasized cutaneous melanoma (stage III and IV, AJCC 2009) have been treated with dendritic cell (DC)-based vaccines at our hospital. Three out of these patients were diagnosed with sarcoidosis after or during long-term DC vaccination therapy (1.20%). Metastatic disease was initially suspected based on the radiographic manifestation of lung masses or bilateral hilar lymphadenopathy...
June 2017: Anticancer Research
https://www.readbyqxmd.com/read/28551249/effect-of-ultrasound-irradiation-on-the-evolution-of-color-properties-and-major-phenolic-compounds-in-wine-during-storage
#7
Qing-An Zhang, Ting-Ting Wang
In this paper, the effects of ultrasound irradiation were investigated on the evolution of color properties and major phenolic compounds during wine storage. The results indicate that the changing trends of color parameters are very similar in both the ultrasonically-treated and untreated wines, meanwhile the evolutions of malvidin-3-O-glucoside, monomeric flavan-3-ols and phenolic acids also demonstrate some similar patterns in all wines during storage, respectively. In summary, the ultrasound irradiation does not only temporally influence the color characteristics and phenolic compounds of wine, but also have a longer effect on their evolutions during wine storage...
November 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28551005/electronic-health-record-use-in-an-affluent-region-in-india-findings-from-a-survey-of-chandigarh-hospitals
#8
Adam C Powell, Jasmine K Ludhar, Yuri Ostrovsky
OBJECTIVES: To characterize the electronic health record (EHR) systems in use in an affluent region of India in order to understand the state-of-the-art within the Indian market. METHODS: A survey on EHR features was created by combining an instrument developed by the Organisation for International Cooperation and Development and an instrument developed by an American team of researchers. An interviewer directly administered the survey to leaders from hospitals in greater Chandigarh which possessed electronic health information systems...
July 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28550919/evaluation-of-a-smoking-cessation-service-in-elective-surgery
#9
Jennifer Saxony, Lis Cowling, Leanne Catchpole, Natalie Walker
BACKGROUND: No best practice service models exist for promoting preoperative smoking cessation support, despite smokers experiencing more perioperative complications than nonsmokers. A novel specialist stop smoking service for patients undergoing elective surgery (called 'ELECT') was established in 2012 in Auckland, New Zealand (NZ). An evaluation of the service was undertaken in 2014. MATERIALS AND METHODS: The ELECT service involved regular staff training and the development of setting-specific and easy-to-use referral procedures...
May 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28550855/summary-of-evidence-about-complications-of-computer-engineered-complete-dentures-is-not-useful-for-informing-clinical-practice
#10
Romina Brignardello-Petersen
No abstract text is available yet for this article.
June 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28550795/thrombocytopenia-associated-with-tavi-the-summary-of-possible-causes
#11
REVIEW
Maciej Mitrosz, Malgorzata Chlabicz, Katarzyna Hapaniuk, Karol A Kaminski, Bozena Sobkowicz, Jaroslaw Piszcz, Slawomir Dobrzycki, Wlodzimierz J Musial, Tomasz Hirnle, Agnieszka M Tycinska
Thrombocytopenia (TP) following transcatheter aortic valve implantation (TAVI) procedure is a common phenomenon but the underlying mechanisms are neither well known nor described. Postinterventional severe TP is related to worse early and late outcome. Moreover, the statement of enhanced platelet and coagulation activation might justify even stronger antiplatelet and anticoagulation therapy following TAVI procedure. Thus, the examination of the pathomechanisms responsible for TP post TAVI seems to be crucial...
May 24, 2017: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28550701/patient-centred-care-in-canada-key-components-and-the-path-forward
#12
Terrence Montague, Amédé Gogovor, John Aylen, Lisa Ashley, Sara Ahmed, Lesli Martin, Bonnie Cochrane, Owen Adams, Joanna Nemis-White
Canadians' health and its care continue to evolve. Chronic diseases affect more than 50% of our aging population, but the majority of public and professional stakeholders retain a sense of care quality. An emergent issue, however, is generating an increasingly wide debate. It is the concept of patient-centred care, including its definition of key components, and efficacy. To advance the evidence base, the 2013-2014 and 2016 Health Care in Canada (HCIC) surveys measured pan-stakeholder levels of support and implementation priorities for frequently proposed components of patient centricity in healthcare...
2017: Healthcare Quarterly
https://www.readbyqxmd.com/read/28550700/optimizing-transitions-of-care-hospital-to-community
#13
Emily Sheridan, Christine Thompson, Tania Pinheiro, Nicole Robinson, Karen Davies, Nancy Whitmore
Discharging patients from the hospital is a complex process, and preventing avoidable readmissions has the potential to improve both the quality of life for patients and the financial sustainability of the healthcare system (Alper et al. 2016). Improving the discharge process is one method to mitigate readmission to the hospital. Historically, St. Thomas Elgin General Hospital (STEGH) consistently experienced higher-than-expected readmission rates, and only 41% of discharge summaries were sent from the hospital to the community primary care within 48 hours...
2017: Healthcare Quarterly
https://www.readbyqxmd.com/read/28550684/long-noncoding-rna-ccat2-knockdown-suppresses-tumorous-progression-by-sponging-mir-424-in-epithelial-ovarian-vancer
#14
Fu Hua, Chang-Hua Li, Xiao-Gang Chen, Xiao-Ping Liu
Epithelial ovarian cancer (EOC) is the one of most common gynecological malignant tumor with highest mortality, meanwhile, series of lncRNAs have been validated to play vital role in EOC tumorigenesis. Colon cancer-associated transcript 2 (CCAT2) has been verified as oncogenic lncRNA in multiple tumors, however, the role of CCAT2 in EOC genesis is still unclear. The purpose of present study is to probe the function of CCAT2 on EOC. Preliminary experiments found that CCAT2 expression was significantly up-regulated in EOC tissue and cell lines compared to noncancerous tissue and cells...
May 21, 2017: Oncology Research
https://www.readbyqxmd.com/read/28550682/long-noncoding-rna-anril-promotes-cervical-cancer-development-by-acting-as-a-sponge-of-mir-186
#15
Jun-Jun Zhang, Dan-Dan Wang, Chen-Xiang Du, Yan Wang
Cervical cancer is a common malignancy of female reproductive system. Long non-coding RNA (lncRNA) has been reported tomodulate tumor progression in multiple cancers. The lncRNA antisense non-coding RNA in the INK4 locus (ANRIL) has been testified as oncogenic molecular in series tumors, however, the function and underlying mechanism involved in cervical cancer oncogenesis is still unclear. In present study, RT-PCR showed that ANRIL expression was significantly up-regulated in cervical cancer tumors and cell lines...
May 22, 2017: Oncology Research
https://www.readbyqxmd.com/read/28550647/genetic-variation-in-the-adipoq-gene-adiponectin-concentrations-and-risk-of-colorectal-cancer-a-mendelian-randomization-analysis-using-data-from-three-large-cohort-studies
#16
Katharina Nimptsch, Mingyang Song, Krasimira Aleksandrova, Michail Katsoulis, Heinz Freisling, Mazda Jenab, Marc J Gunter, Konstantinos K Tsilidis, Elisabete Weiderpass, H Bas Bueno-De-Mesquita, Dawn Q Chong, Majken K Jensen, Chunsen Wu, Kim Overvad, Tilman Kühn, Myrto Barrdahl, Olle Melander, Karin Jirström, Petra H Peeters, Sabina Sieri, Salvatore Panico, Amanda J Cross, Elio Riboli, Bethany Van Guelpen, Robin Myte, José María Huerta, Miguel Rodriguez-Barranco, José Ramón Quirós, Miren Dorronsoro, Anne Tjønneland, Anja Olsen, Ruth Travis, Marie-Christine Boutron-Ruault, Franck Carbonnel, Gianluca Severi, Catalina Bonet, Domenico Palli, Jürgen Janke, Young-Ae Lee, Heiner Boeing, Edward L Giovannucci, Shuji Ogino, Charles S Fuchs, Eric Rimm, Kana Wu, Andrew T Chan, Tobias Pischon
Higher levels of circulating adiponectin have been related to lower risk of colorectal cancer in several prospective cohort studies, but it remains unclear whether this association may be causal. We aimed to improve causal inference in a Mendelian Randomization meta-analysis using nested case-control studies of the European Prospective Investigation into Cancer and Nutrition (EPIC, 623 cases, 623 matched controls), the Health Professionals Follow-up Study (HPFS, 231 cases, 230 controls) and the Nurses' Health Study (NHS, 399 cases, 774 controls) with available data on pre-diagnostic adiponectin concentrations and selected single nucleotide polymorphisms in the ADIPOQ gene...
May 26, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28550628/giovanni-verga-1879-1923-author-of-a-pioneering-treatise-on-pituitary-surgery-the-foundations-of-this-new-field-in-europe-in-the-early-1900s
#17
REVIEW
José M Pascual, Lorenzo Mongardi, Ruth Prieto, Inés Castro-Dufourny, María Rosdolsky, Sewan Strauss, Rodrigo Carrasco, Eduard Winter, Paolo Mazzarello
The field of pituitary surgery was born in the first decade of the twentieth century in Europe, and it evolved rapidly with the development of numerous innovative surgical techniques by some of the founding fathers of neurosurgery. This study investigates the pioneering Italian treatise on pituitary surgery, La Patologia Chirurgica dell'Ipofisi (Surgical Pathology of the Hypophysis), published in 1911 by Giovanni Verga (1879-1923), a surgeon from Pavía and one of Golgi's disciples. This little-known monograph compiles the earliest experience on pituitary surgery through the analysis of the first 50 procedures performed between 1903 and 1911...
May 27, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28550611/-18-f-fluorodeoxyglucose-positron-emission-tomography-in-the-diagnosis-of-malignancy-in-patients-with-paraneoplastic-neurological-syndrome-a-systematic-review-and-meta-analysis
#18
REVIEW
Ana María García Vicente, Roberto C Delgado-Bolton, Mariano Amo-Salas, Jesús López-Fidalgo, Ana Paula Caresia Aróztegui, José Ramón García Garzón, Javier Orcajo Rincón, María José García Velloso, María de Arcocha Torres, Soledad Alvárez Ruíz
PURPOSE: The detection of occult cancer in patients suspected of having a paraneoplastic neurological syndrome (PNS) poses a diagnostic challenge. The aim of our study was to perform a systematic review and meta-analysis to assess the diagnostic performance of FDG PET for the detection of occult malignant disease responsible for PNS. METHODS: A systematic review of the literature (MEDLINE, EMBASE, Cochrane, and DARE) was undertaken to identify studies published in any language...
May 27, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28550595/clinical-pharmacokinetics-and-pharmacodynamics-of-colistin
#19
REVIEW
Nicolas Grégoire, Vincent Aranzana-Climent, Sophie Magréault, Sandrine Marchand, William Couet
In this review, we provide an updated summary on colistin pharmacokinetics and pharmacodynamics. Colistin is an old molecule that is frequently used as last-line treatment for infections caused by multidrug-resistant Gram-negative bacteria. Colistin is a decapeptide administered either as a prodrug, colistin methanesulfonate (CMS), when used intravenously, or as colistin sulfate when used orally. Because colistin binds to laboratory materials, many experimental issues are raised and studies on colistin can be tricky...
May 26, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28550544/-non-pharmacological-migraine-treatment-a-practice-oriented-summary
#20
REVIEW
Thomas Dresler, Bianca Meyer, Peter Kropp
No abstract text is available yet for this article.
June 2017: MMW Fortschritte der Medizin
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