Caixia Ye, Hongyan Duan, Mengyuan Liu, Jianqiang Liu, Jingwen Xiang, Yizhen Yin, Qiong Zhou, Dan Yang, Ruiling Yan, Ruiman Li
PURPOSE: This study aimed to investigate the performance, cost-effectiveness and additional findings of combined detailed ultrasound and biochemical screening for risks of major fetal trisomies in the first-trimester. METHODS: This is a retrospective analysis study, we estimated the risk of trisomies 21, 18 and 13 based on maternal age, fetal nuchal translucency thickness, nasal bone, ductus venosus pulsatility index velocity, tricuspid regurgitation, fetal heart rate, free beta-human chorionic gonadotropin, and pregnancy-associated plasma protein A in singleton pregnant women, and performed non-invasive prenatal testing for women with risks of trisomy 21 between 1:500 and 1:300...
November 8, 2023: Archives of Gynecology and Obstetrics