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https://www.readbyqxmd.com/read/28445978/epidemiological-features-of-lung-giant-cell-carcinoma-and-therapy-for-patients-with-egfr-mutations-based-on-case-reports-and-the-surveillance-epidemiology-and-end-results-seer-database
#1
Shan-Shan Weng, Ying Cao, Xiu-Jun Tang, Li-Zhen Zhu, Yi-Nuo Tan, Cai-Xia Dong, Jia-Qi Chen, Hong Shen, Ying Yuan
Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are the standard first line treatment for advanced non-small cell lung cancer (NSCLC) with sensitive EGFR mutations. Among NSCLC, giant cell carcinoma of the lung (GCCL) is a rare pathological subtype with poor prognosis, with no confirmed evidence about its epidemiological features or therapeutic efficiency of EGFR-TKIs. We present two advanced GCCLs with sensitive EGFR mutations, also collected the cases of GCCL from our hospital and the Surveillance, Epidemiology, and End Results (SEER) program...
April 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28445875/double-incision-approach-and-early-rehabilitation-in-a-complicated-bicondylar-br-tibial-plateau-fracture-a-case-report-br-br
#2
Saverio Affatato, Maurizio Montalti, Claudio Masetti, Federico Giardina, Alessandra Sudanese
OBJECTIVE: The main goal of this case was to report the treatment of bicondylar fractures of the tibial plateau and the restoration of the metaphyseo-diaphyseal dissociation. CLINICAL PRESENTATION AND INTERVENTION: A 54-year old man who was cycling had a road accident that caused a closed fracture of the right tibial plateau and proximal fibula diagnosed by x-rays. Patient had surgical procedure and was immobilized with a long-leg splint for 4 weeks. After immobilization, aggressive rehabilitation was done...
April 26, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/28445623/life-threatening-injury-caused-by-complete-impalement-of-a-toothbrush-case-report
#3
Akiko Umibe, Kazuhiro Omura, Takuya Hachisu, Utaro Anazawa, Yasuhiro Tanaka
Toothbrushes are the most common cause of foreign body injury to the oral cavity in children, but complete impalement by a toothbrush is an extremely rare occurrence and has not been reported previously. This report describes a 28-month girl who fell from a one-meter ledge while brushing her teeth. Her toothbrush penetrated the oral cavity and could not be removed, so she was rushed to the hospital with the toothbrush in place. Contrast-enhanced computed tomography showed penetration of the toothbrush from the oral cavity into and through the right posterior neck at the level of the bifurcation of the common carotid artery...
April 26, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28445318/renal-failure-caused-by-a-partly-calcified-aortic-aneurysm-in-a-patient-with-dabigatran-therapy-a-case-report
#4
Philipp Jud, Thomas Gary, Kurt Tiesenhausen, Rupert Portugaller, Gerald Hackl, Marianne Brodmann
RATIONALE: Abdominal aortic aneurysms (AAAs) are mostly asymptomatic. If aortic aneurysms become symptomatic, complications include peripheral embolization, acute aortic occlusion, and aortic rupture. However, there are also unusual complications caused by aortic aneurysms. PATIENT CONCERNS: An 87-old male with dabigatran therapy presented with newly developed melena and acute renal failure. Radiological imaging revealed an AAA with thrombotic and calcified deposits which affected the renal arteries...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445312/early-progression-of-brain-atrophy-in-patients-with-anti-n-methyl-d-aspartate-receptor-encephalitis-case-reports
#5
Hiroshi Kataoka, Nobuhiro Sawa, Yasuyo Tonomura, Satoshi Ueno
BACKGROUND: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis responds to immunnotherapy, and approximately 80% of patients with this disorder fully recover or have only minor sequelae. Brain magnetic resonance imaging (MRI) does not show a specific abnormality, but some patients have progressive cerebral atrophy. The cerebral atrophy can become reversible after clinical improvement. METHODS: We describe 3 patients with diffuse cerebral atrophy (DCA) on serial brain MRI...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445305/a-case-report-of-painless-type-a-aortic-dissection-with-intermittent-convulsive-syncope-as-initial-presentation
#6
Chun-Hsien Chen, Kuan-Ting Liu
RATIONALE: The initial presenting symptoms and signs of acute aortic dissection are so diverse that it makes early and accurate diagnosis arduous. Painless and convulsive syncope due to cardiac arrhythmia were not typical presentations of acute aortic dissection. PATIENT CONCERNS: A 61-year-old male presenting with transient consciousness loss and suspected seizure attack was sent to emergency room (ER) by ambulance. Consciousness loss accompanying with upward gaze and limb convulsion was noted in ER, and electrocardiogram monitor recorded a transient cardiac asystole then spontaneous recovery of sinus rhythm...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445302/cholestasis-caused-by-panhypopituitarism-and-acquired-cytomegalovirus-infection-in-a-2-month-old-male-infant-a-case-report
#7
U Chan, Wai-Tao Chan, Wei-Hsin Ting, Che-Sheng Ho, Hsi-Che Liu, Hung-Chang Lee
RATIONALE: Septo-optic dysplasia (SOD) is a rare congenital disorder that may cause jaundice in infants. However, it is usually prone to neglect and misdiagnosis in infants with cholestasis because endocrine disorder such as panhypopituitarism is rare in the cause of infantile cholestasis. We report a case of SOD concurrent with acquired cytomegalovirus (CMV) infection, who presented with prolonged jaundice as the first clinical sign. PATIENT CONCERNS: The patient was a 2-month-old male infant who presented with cholestasis, combined with fever and panhypopituitarism...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445300/malignant-phosphaturic-mesenchymal-tumor-with-pulmonary-metastasis-a-case-report
#8
Shui Qiu, Li-Li Cao, Yue Qiu, Ping Yan, Zi-Xuan Li, Jiang Du, Li-Mei Sun, Qing-Fu Zhang
RATIONALE: Phosphaturic mesenchymal tumor (PMT) is a new tumor entity of soft tissue and bone tumor recently accepted by the World Health Organization, which typically causes the paraneoplastic syndrome of tumor-induced osteomalacia (TIO). The majority of PMTs follow a benign clinical course and local recurrence occurs in < 10% of cases, malignant PMTs with distant organ metastasis are extremely uncommon. PATIENT CONCERNS: We reported a 41-year-old woman who was diagnosed with PMT 10 years ago with a repeated recurrence and pulmonary metastasis...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445299/endoscopic-ultrasonography-predicts-early-esophageal-variceal-bleeding-in-liver-cirrhosis-a-case-report
#9
Changjun Men, Guoliang Zhang
RATIONALE: Bleeding esophageal and gastric varices constitute a serious complication in liver cirrhosis. Previous studies have shown that endoscopic ultrasonography (EUS) can be used to predict early esophageal variceal bleeding in liver cirrhosis. PATIENT CONCERNS: We report a case of a 46-year-old man with hepatitis B liver cirrhosis (CTP score, 5; Child-Pugh class, A) who was admitted to our hospital due to a decreased appetite lasting 1 week. DIAGNOSIS: He was initially diagnosed with decompensated hepatitis B cirrhosis; an abdominal computed tomography (CT) scan indicated a diagnosis of liver cirrhosis and portal hypertension (PHT)...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445295/metastatic-breast-cancer-to-the-rectum-a-case-report-with-emphasis-on-mri-features
#10
Li Ching Lau, Bernard Wee, Shi Wang, Yee Liang Thian
RATIONALE: Less than 1% of breast carcinomas metastasize to the gastrointestinal tract. The diagnosis is frequently not recognized especially when the history of breast carcinoma is remote. PATIENT CONCERNS: A 61-year-old female with a remote history of breast carcinoma presented with a 3-month history of change in bowel habits. Colonoscopy showed a circumferential rectal mass with initial impression of primary rectal cancer. MRI of the rectum showed findings that are atypical for primary rectal cancer...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445282/a-case-report-of-sj%C3%A3-gren-syndrome-manifesting-bilateral-basal-ganglia-lesions
#11
Bing Niu, Zhenzhen Zou, Yuqin Shen, Bingzhen Cao
RATIONALE: Peripheral neurological complications in primary Sjögren's syndrome (pSS) seem the most common, however the involvement of central nervous system (CNS) remains unclear. While abnormalities in pSS revealed by brain magnetic resonance imaging (MRI) are usually small discrete hyperintense areas in the white matter on T2-FLAIR weighted MRI, massive brain lesions have been rarely reported, particularly in bilateral basal ganglia. PATIENT CONCERNS: A 51-year-old woman exhibited dizziness, slurred speech and hemiplegia as a manifestation of pSS...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445255/peutz-jeghers-syndrome-with-intermittent-upper-intestinal-obstruction-a-case-report-and-review-of-the-literature
#12
Shou-Xing Duan, Guang-Huan Wang, Jun Zhong, Wen-Hui Ou, Ma-Xian Fu, Fu-Sheng Wang, Shu-Hua Ma, Jian-Hong Li
RATIONALE: Peutz-Jeghers syndrome (PJS) is an autosomal dominant genetic syndrome characterized by a unique type of gastrointestinal hamartomatous polyp associated with oral and anal mucocutaneous pigmentations. Peutz-Jeghers polyps occur most numerously in the small intestine but frequently in the colon and stomach, only a few cases have been reported in the duodenum. PATIENT CONCERN: A further family history survey discovered 10 out of 14 members of the family (in 4 generations) had mucocutaneous pigmentations, but many of them were living in rural areas where they had no access to specialized medical services, so none were checked with endoscopy for polyps of hamartoma...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445254/the-clinical-features-treatment-and-prognosis-of-primary-mediastinal-malignant-melanoma-a-case-report
#13
ZiHai Li, Hui Jia, Baijiang Zhang, Yongming Zhang, Hui Li, Pingping Song
RATIONALE: Primary malignant melanoma (MM) of the mediastinum is exceedingly rare; a review of the English-language literature reveals only a small number of case reports. In this paper, we discuss a case of primary mediastinal MM and present a review of the relevant literature on its clinical features and treatment. PATIENT CONCERNS: A 52-year-old male presenting with back pain was admitted to our hospital for treatment. Imaging examination revealed an anterior mediastinal mass and no evidence of other metastatic or primary lesions...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445175/traumatic-ventral-septal-defect-after-stab-wound-to-the-chest-missed-by-transthoracic-echocardiogram-a-case-report
#14
Abimbola O Faloye, Raphael Y Gershon
Traumatic ventral septal defect may be sustained after either blunt force or penetrating trauma to the chest. Severity ranges from asymptomatic to acute decompensated heart failure. Our patient suffered a stab wound to the chest and was initially taken to the operating room for repair of a lacerated right ventricle. Subsequent postoperative hemodynamic deterioration prompted a bedside transthoracic echocardiogram, which failed to identify causal factors. A transesophageal echocardiogram performed immediately after ventral septal defect was demonstrated...
April 25, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28445174/obstetric-anesthesia-for-a-pregnant-woman-with-brainstem-cavernous-malformations-a-case-report
#15
Misuzu Hayashi, Manabu Kakinohana
There are no well-defined guidelines for obstetric and anesthetic management of pregnant patients with cerebral cavernous malformations (CMs). We need to pay careful attention to the attendant risks of both general and neuraxial anesthesia in this population. Here, we describe the anesthetic management of a pregnant woman with brainstem CMs who underwent cesarean delivery. We selected a general anesthetic technique because of concerns of undesirable effects of neuraxial anesthesia in the presence of cerebral CMs...
April 25, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28445159/invasive-pulmonary-aspergillosis-in-patients-with-chronic-obstructive-pulmonary-disease-a-case-report-and-review-of-the-literature
#16
Zhiyao Bao, Hong Chen, Min Zhou, Guochao Shi, Qingyun Li, Huanying Wan
Invasive pulmonary aspergillosis (IPA) is an infection that often occurs in immunocompromised patients and has a high mortality rate. In recent years, the reported incidence of IPA in the context of chronic obstructive pulmonary disease (COPD) has seemingly increased. The combination of factors such as long-term corticosteroid use, increasing rate of bacterial exacerbations over time, lung immune imbalance, and malnutrition are responsible for the emergence of IPA in COPD patients. A diagnosis of IPA in COPD patients is difficult to make, which explains the delay in antifungal therapy and the high mortality rate...
April 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28445006/equine-atypical-myopathy-in-the-uk-epidemiological-characteristics-of-cases-reported-from-2011-to-2015-and-factors-associated-with-survival
#17
S González-Medina, J L Ireland, R J Piercy, J R Newton, D M Votion
BACKGROUND: Equine atypical myopathy (AM) is a toxic rhabdomyolysis associated with ingestion of hypoglycin A, derived typically in Europe, from Acer pseudoplatanus tree. Despite the wide distribution of this tree species in the UK, the number of cases reported annually varies, and there has been an apparent increase in prevalence in recent years. Although AM was first recognised in the UK, epidemiological studies have never been conducted focused solely on this country. OBJECTIVES: To describe the spatiotemporal distribution, presentation, treatment and outcome of AM cases reported in the UK...
April 26, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28444954/clinical-presentation-and-outcome-of-children-with-central-diabetes-insipidus-associated-with-a-self-limited-or-transient-pituitary-stalk-thickening-diagnosed-as-infundibuloneurohypophysitis
#18
J Schaefers, M Cools, K De Waele, I Gies, V Beauloye, P Lysy, I Francois, D Beckers, J De Schepper
OBJECTIVE: Despite lymphocytic or autoimmune infundibuloneurohypophysitis (INH) is an increasingly recognized etiology in children with central diabetes insipidus, clinical data on epidemiology (clinical evolution, predisposing factors, complications), diagnosis and management of this entity are limited and mostly based on published case reports. The aim of this study was to gain a broader insight in the natural history of this disease by analyzing the clinical presentation, radiological pituitary stalk changes, associated autoimmunity and hormonal deficiencies in children with CDI and a self-limiting or transient stalk thickening (ST), diagnosed as autoimmune INH, during the last 15 years in four Belgian university hospitals...
April 26, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28444812/a-survey-on-abnormal-uterine-bleeding-among-radiographers-with-frequent-mri-exposure-using-intrauterine-contraceptive-devices
#19
A Huss, K Schaap, H Kromhout
PURPOSE: Based on a previous case report of menometrorrhagia (prolonged/excessive uterine bleeding, occurring at irregular and/or frequent intervals) in MRI workers with intrauterine devices (IUDs), it was evaluated whether this association could be confirmed. METHODS: A survey was performed among 381 female radiographers registered with their national association. Logistic regression was used to analyze associations of abnormal uterine bleeding with the frequency of working with MRI scanners, presence near the scanner/in the scanner room during image acquisition, and with scanner strength or type...
April 25, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28444655/bilateral-infiltrative-dacryoadenitis-and-granulomatous-pneumonia-in-an-11-year-old-boy-a-case-report
#20
Susanne C Diesner, Julius Lukas, Eva Stifter, Adalbert Raimann, Edith Nachbaur, Thomas Eiwegger, Sabine Renner, Wolfgang Emminger, Silvana Geleff, Zsolt Szepfalusi
No abstract text is available yet for this article.
March 2017: Klinische Pädiatrie
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