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pulmonary nodule guidelines

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https://www.readbyqxmd.com/read/29780632/management-pathways-for-solitary-pulmonary-nodules
#1
REVIEW
Masaoki Ito, Yoshihiro Miyata, Morihito Okada
Pulmonary nodules are often detected during the clinical course of several diseases or through routine screening. Various guidelines have proposed management algorithms for suspicious solitary nodules in lung cancer. Generally, solitary pulmonary nodules are managed according to nodule appearance and risk of lung cancer using low-dose, thin section computed tomography (CT). Liquid biopsy is promising for diagnosis, therapeutic-monitoring and follow-up in lung cancer; however, diagnosis and management pathways based on genetic examination alone have not been established...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29722490/-ct-scan-in-early-detection-of-lung-cancer-in-patients-with-chronic-obstructive-pulmonary-disease-a-retrospective-monocentric-study
#2
S Takkal, A Van Muylem, P A Gevenois
OBJECTIVE: To explore the possible benefit of detecting lung cancer in COPD patients and to assess the pulmonologist's compliance with the Fleischner Society guidelines for management of pulmonary nodules. METHODS: This monocentric retrospective study was approved by the institutional ethical Committee. Patients with COPD undergoing a CT scan between January 2010 and March 2017 were included. Depending on CT indication (respectively screening or other indications), patients were divided into Group 1 and 2...
2018: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/29708784/lung-cancer-screening-guidelines-how-readable-are-internet-based-patient-education-resources
#3
David Richard Hansberry, Michael D White, Michael D'Angelo, Arpan V Prabhu, Sarah Kamel, Paras Lakhani, Baskaran Sundaram
OBJECTIVE: Following the findings of the National Lung Screening Trial, several national societies from multiple disciplines have endorsed the use of low-dose chest CT to screen for lung cancer. Online patient education materials are an important tool to disseminate information to the general public regarding the proven health benefits of lung cancer screening. This study aims to evaluate the reading level at which these materials related to lung cancer screening are written. MATERIALS AND METHODS: The four terms "pulmonary nodule," "radiation," "low-dose CT," and "lung cancer screening" were searched on Google, and the first 20 online resources for each term were downloaded, converted into plain text, and analyzed using 10 well-established readability scales...
April 30, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29682290/british-thoracic-society-quality-standards-for-the-investigation-and-management-of-pulmonary-nodules
#4
David Baldwin, Matthew Callister, Ahsan Akram, Paul Cane, Jeanette Draffan, Kevin Franks, Fergus Gleeson, Richard Graham, Puneet Malhotra, Philip Pearson, Manil Subesinghe, David Waller, Ian Woolhouse
Introduction: The purpose of the quality standards document is to provide healthcare professionals, commissioners, service providers and patients with a guide to standards of care that should be met for the investigation and management of pulmonary nodules in the UK, together with measurable markers of good practice. Methods: Development of British Thoracic Society (BTS) Quality Standards follows the BTS process of quality standard production based on the National Institute for Health and Care Excellence process manual for the development of quality standards...
2018: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/29672887/young-age-is-associated-with-increased-rates-of-residual-recurrent-pediatric-differentiated-thyroid-carcinoma
#5
Sarah Hampson, Derek Stephens, Jonathan D Wasserman
OBJECTIVE: Differentiated thyroid carcinoma is rare in young children. There are conflicting data as to whether disease in this age group differs from that in adolescents and specifically, if it is more aggressive. Current practice guidelines do not differentiate treatment between these groups, but speculate that differences may exist. We sought to compare clinical features, treatment and outcomes between children (<12 years) and adolescents (12-18 years) with thyroid nodules and thyroid malignancy over a 20 year period...
April 19, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29650547/-in-vivo-growth-of-60-non-screening-detected-lung-cancers-a-computed-tomography-study
#6
Onno M Mets, Kaman Chung, Pieter Zanen, Ernst T Scholten, Wouter B Veldhuis, Bram van Ginneken, Mathias Prokop, Cornelia M Schaefer-Prokop, Pim A de Jong
Current pulmonary nodule management guidelines are based on nodule volume doubling time, which assumes exponential growth behaviour. However, this is a theory that has never been validated in vivo in the routine-care target population. This study evaluates growth patterns of untreated solid and subsolid lung cancers of various histologies in a non-screening setting.Growth behaviour of pathology-proven lung cancers from two academic centres that were imaged at least three times before diagnosis (n=60) was analysed using dedicated software...
April 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29622071/pulmonary-nodule-management-in-lung-cancer-screening-a-pictorial-review-of-lung-rads-version-1-0
#7
REVIEW
Myrna C B Godoy, Erika G L C Odisio, Mylene T Truong, Patricia M de Groot, Girish S Shroff, Jeremy J Erasmus
The number of screening-detected lung nodules is expected to increase as low-dose computed tomography screening is implemented nationally. Standardized guidelines for image acquisition, interpretation, and screen-detected nodule workup are essential to ensure a high standard of medical care and that lung cancer screening is implemented safely and cost effectively. In this article, we review the current guidelines for pulmonary nodule management in the lung cancer screening setting.
May 2018: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/29607803/molecular-imaging-in-oncology-using-positron-emission-tomography
#8
Thorsten Derlin, Viktor Grünwald, Jörg Steinbach, Hans-Jürgen Wester, Tobias L Ross
BACKGROUND: Anatomical and molecular data can be acquired simultaneously through the use of positron emission tomography (PET) in combination with computed tomography (CT) or magnetic resonance imaging (MRI) as a hybrid technique. A variety of radiopharmaceuticals can be used to characterize various metabolic processes or to visualize the expression of receptors, enzymes, and other molecular target structures. METHODS: This review is based on pertinent publications retrieved by a selective search in PubMed, as well as on guidelines from Germany and abroad and on systematic reviews and meta-analyses...
March 16, 2018: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29587931/-management-strategies-of-pulmonary-ground-galss-nodule
#9
Qun Wang
Pulmonary ground glass nodule (GGN) is a term of radiological manifestation, which may be malignant or benign. The management for pulmonary GGN remains controversial. Both Fleischner society and National Comprehensive Cancer Network (NCCN) panel updated the guideline for the management of GGN in 2017. Compared with previous versions, the indication for surgery or biopsy is stricter, and the recommended follow-up interval is prolonged. In clinical practice, the size of GGN component, the size of consolidation component, dynamic change during follow-up and computed tomography (CT) value are the four factors that help surgeons to decide the timing of surgery...
March 20, 2018: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/29587930/-shanghai-pulmonary-hospital-experts-consensus-on-the-management-of-ground-glass-nodules-suspected-as-lung-adenocarcinoma-version-1
#10
Gening Jiang, Chang Chen, Yuming Zhu, Dong Xie, Jie Dai, Kaiqi Jin, Yingran Shen, Haifeng Wang, Hui Li, Lanjun Zhang, Shugeng Gao, Keneng Chen, Lei Zhang, Xiao Zhou, Jingyun Shi, Hao Wang, Boxiong Xie, Lei Jiang, Jiang Fan, Deping Zhao, Qiankun Chen, Liang Duan, Wenxin He, Yiming Zhou, Hongcheng Liu, Xiaogang Zhao, Peng Zhang, Xiong Qin
Background and objective As computed tomography (CT) screening for lung cancer becomes more common in China, so too does detection of pulmonary ground-glass nodules (GGNs). Although anumber of national or international guidelines about pulmonary GGNs have been published,most of these guidelines are produced by respiratory, oncology or radiology physicians, who might not fully understand the progress of modern minimal invasive thoracic surgery, and these current guidelines may overlook or underestimate the value of thoracic surgery in the management of pulmonary GGNs...
March 20, 2018: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/29538730/challenges-in-the-diagnosis-and-treatment-of-mucormycosis
#11
A Skiada, C Lass-Floerl, N Klimko, A Ibrahim, E Roilides, G Petrikkos
The diagnosis and treatment of mucormycosis are challenging. The incidence of the disease seems to be increasing. Hematological malignancies are the most common underlying disease in countries with high income and uncontrolled diabetes in developing countries. Clinical approach to diagnosis lacks sensitivity and specificity. Radiologically, multiple (≥10) nodules and pleural effusion are reportedly associated with pulmonary mucormycosis. Another finding on computerized tomography (CT) scan, which seems to indicate the presence of mucormycosis, is the reverse halo sign...
April 1, 2018: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/29492838/prevalence-and-variability-in-reporting-of-clinically-actionable-incidental-findings-on-attenuation-correction-ct-scans-in-a-veteran-population
#12
B Julie He, Brian J Malm, Michelle Carino, Mehran M Sadeghi
BACKGROUND: Myocardial perfusion imaging (MPI) often employs attenuation-correction computed tomography (CTAC) to reduce attenuation artifacts and improve specificity. While there is no specific guideline on how they should be reported, incidental noncardiac findings identified on these scans may be clinically significant. The prevalence of these findings in veterans is not currently known. In addition, variability in reporting these findings may depend on the interpreting physician's specialty...
February 28, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29492597/preoperative-watchful-waiting-time-and-surgical-outcome-of-patients-with-non-small-cell-lung-cancer-found-by-chest-low-dose-ct-screening
#13
Takaomi Hanaoka, Makoto Kurai, Mitsuyo Okada, Satoshi Ishizone, Fumitoshi Karasawa, Akira Iizuka
BACKGROUNDS: Chest low-dose CT screening (LDCTS) has been finding unprecedented numbers of peripheral non-small cell lung cancers (NSCLC) at an early stage and increased the number of patients with surgical indication. It is important to explore the influence of preoperative watchful-waiting time (WWT) on surgical outcomes. Objective is to clarify relationship between WWT and surgical outcomes of LDCTS-finding NSCLC from the view point of treatment delay. METHODS: Total 283 cases of NSCLC, found by LDCTS and consecutively resected, were surveyed for preoperative WWT and surgical outcomes...
February 28, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29446832/an-assessment-of-18-f-fdg-pet-ct-for-thoracic-screening-and-risk-stratification-of-pulmonary-nodules-in-multiple-endocrine-neoplasia-type-1
#14
Alvin So, Owen Pointon, Richard Hodgson, John Burgess
CONTEXT: Bronchopulmonary neuroendocrine tumours (bpNETs) and thymic carcinoid (ThC) are features of multiple endocrine neoplasia type 1 (MEN 1), and surveillance guidelines recommend periodic thoracic imaging. The optimal thoracic imaging modality and screening frequency remain uncertain as does the prognosis of small lung nodules when identified. OBJECTIVES: To evaluate fluorodeoxyglucose positron emission tomography/computed tomography (18 F-FDG PET/CT) for identification and prognostic assessment of thoracic lesions in MEN 1...
May 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29313653/lung-cancer-screening-and-evaluation-of-patients-with-solitary-pulmonary-nodules
#15
REVIEW
Timothy F Mott
Low-dose computed tomography (CT) scan is the only modality currently considered acceptable for lung cancer screening in high-risk populations. Screening recommendations vary. The US Preventive Services Task Force recommends annual low-dose CT scan to screen high-risk patients (ie, asymptomatic patients ages 55 to 80 years with a 30 pack-year smoking history and who currently smoke or have quit within the previous 15 years). The American Academy of Family Physicians recommends a shared decision-making discussion between the clinician and patient regarding the benefits and potential harms of screening...
January 2018: FP Essentials
https://www.readbyqxmd.com/read/29261826/communication-about-the-probability-of-cancer-in-indeterminate-pulmonary-nodules
#16
Amelia W Maiga, Stephen A Deppen, Pierre P Massion, Carol Callaway-Lane, Rhonda Pinkerman, Robert S Dittus, Eric S Lambright, Jonathan C Nesbitt, Eric L Grogan
Importance: Clinical guidelines recommend that clinicians estimate the probability of malignancy for patients with indeterminate pulmonary nodules (IPNs) larger than 8 mm. Adherence to these guidelines is unknown. Objectives: To determine whether clinicians document the probability of malignancy in high-risk IPNs and to compare these quantitative or qualitative predictions with the validated Mayo Clinic Model. Design, Setting, and Participants: Single-institution, retrospective cohort study of patients from a tertiary care Department of Veterans Affairs hospital from January 1, 2003, through December 31, 2015...
December 20, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29221286/automatic-lung-rads%C3%A2-classification-with-a-natural-language-processing-system
#17
Sebastian E Beyer, Brady J McKee, Shawn M Regis, Andrea B McKee, Sebastian Flacke, Gilan El Saadawi, Christoph Wald
Background: Our aim was to train a natural language processing (NLP) algorithm to capture imaging characteristics of lung nodules reported in a structured CT report and suggest the applicable Lung-RADS™ (LR) category. Methods: Our study included structured, clinical reports of consecutive CT lung screening (CTLS) exams performed from 08/2014 to 08/2015 at an ACR accredited Lung Cancer Screening Center. All patients screened were at high-risk for lung cancer according to the NCCN Guidelines® ...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29196857/pulmonary-subsolid-nodules-value-of-semi-automatic-measurement-in-diagnostic-accuracy-diagnostic-reproducibility-and-nodule-classification-agreement
#18
Hyungjin Kim, Chang Min Park, Eui Jin Hwang, Su Yeon Ahn, Jin Mo Goo
OBJECTIVES: We hypothesized that semi-automatic diameter measurements would improve the accuracy and reproducibility in discriminating preinvasive lesions and minimally invasive adenocarcinomas from invasive pulmonary adenocarcinomas appearing as subsolid nodules (SSNs) and increase the reproducibility in classifying SSNs. METHODS: Two readers independently performed semi-automatic and manual measurements of the diameters of 102 SSNs and their solid portions. Diagnostic performance in predicting invasive adenocarcinoma based on diameters was tested using logistic regression analysis with subsequent receiver operating characteristic curves...
December 1, 2017: European Radiology
https://www.readbyqxmd.com/read/29195841/incidental-pulmonary-nodules-in-emergent-coronary-ct-angiography-for-suspected-acute-coronary-syndrome-impact-of-revised-2017-fleischner-society-guidelines
#19
Jan-Erik Scholtz, Michael T Lu, Sandeep Hedgire, Nina M Meyersohn, George R Oliveira, Anand M Prabhakar, Rajiv Gupta, Mannudeep K Kalra, Jo-Anne O Shepard, Udo Hoffmann, Brian B Ghoshhajra
BACKGROUND: Pulmonary nodules (PN) are frequently detected incidentally during coronary computed tomography angiography (CTA). We evaluated whether the 2017 Fleischner Society guidelines may result in a decrease of follow-up testing of incidental PN as compared to prior guidelines in patients undergoing coronary CTA. METHODS: We conducted a retrospective study of a registry of emergency department patients who underwent coronary CTA for acute coronary syndrome assessment between 2012 and 2017...
January 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29173759/early-detection-of-lung-cancer-using-ultra-low-dose-computed-tomography-in-coronary-ct-angiography-scans-among-patients-with-suspected-coronary-heart-disease
#20
Matheus Zanon, Gabriel Sartori Pacini, Vinicius Valério Silveiro de Souza, Edson Marchiori, Gustavo Souza Portes Meirelles, Gilberto Szarf, Felipe Soares Torres, Bruno Hochhegger
OBJECTIVES: To assess whether an additional chest ultra-low-dose CT scan to the coronary CT angiography protocol can be used for lung cancer screening among patients with suspected coronary artery disease. METHODS: 175 patients underwent coronary CT angiography for assessment of coronary artery disease, additionally undergoing ultra-low-dose CT screening to early diagnosis of lung cancer in the same scanner (80kVp and 15mAs). Patients presenting pulmonary nodules were followed-up for two years, repeating low-dose CTs in intervals of 3, 6, or 12 months based on nodule size and growth rate in accordance with National Comprehensive Cancer Network guidelines...
December 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
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