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https://www.readbyqxmd.com/read/27912898/a-clinical-prediction-model-for-prolonged-air-leak-after-pulmonary-resection
#1
Adam Attaar, Daniel G Winger, James D Luketich, Matthew J Schuchert, Inderpal S Sarkaria, Neil A Christie, Katie S Nason
OBJECTIVE: Prolonged air leak increases costs and worsens outcomes after pulmonary resection. We aimed to develop a clinical prediction tool for prolonged air leak using pretreatment and intraoperative variables. METHODS: Patients who underwent pulmonary resection for lung cancer/nodules (from January 2009 to June 2014) were stratified by prolonged parenchymal air leak (>5 days). Using backward stepwise logistic regression with bootstrap resampling for internal validation, candidate variables were identified and a nomogram risk calculator was developed...
October 14, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27909682/case-report-of-invasive-disseminated-candidiasis-with-peripheral-nodular-cavitary-lesions-in-the-lung
#2
Hafiza Arshad, Silvia Garcia, Misbahuddin Khaja
We report a case of invasive candidiasis presenting as multiple lung nodules and cavitary lesions with minimal pleural effusion. Candida infections of the lung are rare but can occur after hematologic dissemination of the yeast from other body sites, such as the skin and the gastrointestinal and genitourinary tracts. Here, we describe the case of a 56-year-old female with a history of end-stage renal disease (ESRD) who presented with fever, productive cough, and pulmonary nodules and cavitary lesions seen on a chest computed tomography (CT)...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27909285/-multiple-pulmonary-sclerosing-pneumocytoma-with-abnormal-accumulation-of-fluorodeoxyglucose-positron-emission-tomography-diagnosed-by-surgical-treatment-report-of-a-case
#3
Kantaro Hara, Nobuhiro Izumi, Takuma Tsukioka, Hiroaki Komatsu, Satoshi Okada, Michihito Toda, Ryuichi Ito, Toshihiko Shibata, Noritoshi Nishiyama
A 36-year-old Chinese woman was referred to our hospital for further examination of an abnormal shadow on chest X-ray. Chest computed tomography(CT) revealed a 5 mm circular nodule in diameter in right lung S3 and a 32 mm mass in diameter in right lung S7. The S7 mass showed an abnormal accumulation of SUVmax=4.0 on positron emission tomography( PET)-CT. Transbronchial biopsy was performed, but failed to rule out possible malignancy. Differential diagnoses were multiple lung benign tumor, multiple lung metastases from unknown primary cancer, malignant lymphoma or primary lung cancer, and so on...
December 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27908443/a-retrospective-validation-study-of-three-models-to-estimate-the-probability-of-malignancy-in-patients-with-small-pulmonary-nodules-from-a-tertiary-oncology-follow-up-centre
#4
A Talwar, N M Rahman, T Kadir, L C Pickup, F Gleeson
AIM: To estimate the probability of malignancy in small pulmonary nodules (PNs) based on clinical and radiological characteristics in a non-screening population that includes patients with a prior history of malignancy using three validated models. MATERIALS AND METHODS: Retrospective data on clinical and radiological characteristics was collected from the medical records of 702 patients (379 men, 323 women; range 19-94 years) with PNs ≤12 mm in diameter at a single centre...
November 28, 2016: Clinical Radiology
https://www.readbyqxmd.com/read/27904816/an-unusual-presentation-of-nocardiosis-in-an-allogeneic-transplant-recipient
#5
Uroosa Ibrahim, Amina Saqib, Farhan Mohammad, Terenig Terjanian
Nocardiosis is a rare cause of opportunistic infection post hematopoietic stem cell transplant (HSCT) occurring in about 0.3% of patients. The risk factors include delayed immune reconstitution, prolonged neutropenia, and graft-versus-host disease. The most common site of infection is the lung, followed by the brain and the skin. Concomitant pulmonary and central nervous system (CNS) nocardiosis is an extremely rare entity as presented in our case. We present the case of a 72-year-old male at 137 days post transplant presenting with complaints of headache and slurred speech...
October 17, 2016: Curēus
https://www.readbyqxmd.com/read/27897029/a-method-for-evaluating-the-performance-of-computer-aided-detection-of-pulmonary-nodules-in-lung-cancer-ct-screening-detection-limit-for-nodule-size-and-density
#6
Hajime Kobayashi, Masaki Ohkubo, Akihiro Narita, Janaka C Marasinghe, Kohei Murao, Toru Matsumoto, Shusuke Sone, Shinichi Wada
OBJECTIVES: We propose the application of virtual nodules to evaluate the performance of computer-aided detection (CAD) of lung nodules in cancer screening using low-dose computed tomography (CT). METHODS: The virtual nodules were generated based on the spatial resolution measured for a CT system used in an institution providing cancer screening and were fused into clinical lung images obtained at that institution, allowing site-specificity. First, we validated the virtual nodules as an alternative to artificial nodules inserted into a phantom...
November 29, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27894618/primary-pulmonary-pleural-melanoma-in-a-13-year-old-presenting-as-pleural-effusion
#7
Nick Baniak, Mark Podberezin, Selliah C Kanthan, Rani Kanthan
Melanoma in children, adolescents, and young adults is uncommon and reported almost exclusively as cutaneous melanoma. Melanoma presenting as a pleural effusion is very rare in adults and not reported in the pediatric population. Additionally, primary pulmonary melanoma is overall very rare and undocumented in pediatric patients. Furthermore, the distinction between a primary pulmonary/pleural melanoma versus a regressed cutaneous melanoma with pulmonary/pleural metastases remains extremely challenging. We discuss a case of a previously healthy 13-year-old girl that presented with a left-sided pleural effusion...
November 16, 2016: Pathology, Research and Practice
https://www.readbyqxmd.com/read/27893684/ct-findings-of-small-cell-lung-carcinoma-can-recognizable-features-be-found
#8
Dongjun Lee, Ji Young Rho, Seunghun Kang, Koun Joy Yoo, Hye Jeong Choi
The purpose of this study was to clarify the recognizable computed tomography (CT) features of small cell lung carcinoma (SCLC).Contrast enhanced CT scans were reviewed retrospectively for mass location, mediastinal extension, and other concomitant findings in 142 patients with pathologically proven SCLC. SCLC was classified into hilar mass only (type I), hilar mass with ipsilateral mediastinal extension (type II), hilar mass with bilateral mediastinal extension (type III), and peripheral mass (type IV). When mediastinal lymphadenopathy (m-LAP) was indistinguishable from a hilar mass, we defined it as a mediastinal conglomerate mass (m-CM)...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27890986/correlation-of-chest-computed-tomography-findings-with-dyspnea-and-lung-functions-in-post-tubercular-sequelae
#9
Ananya Panda, Ashu Seith Bhalla, Raju Sharma, Anant Mohan, Vishnu Sreenivas, Umasankar Kalaimannan, Ashish Dutt Upadhyay
AIMS: To study the correlation between dyspnea, radiological findings, and pulmonary function tests (PFTs) in patients with sequelae of pulmonary tuberculosis (TB). MATERIALS AND METHODS: Clinical history, chest computed tomography (CT), and PFT of patients with post-TB sequelae were recorded. Dyspnea was graded according to the Modified Medical Research Council (mMRC) scale. CT scans were analyzed for fibrosis, cavitation, bronchiectasis, consolidation, nodules, and aspergilloma...
November 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27889655/a-prediction-model-based-on-biomarkers-and-clinical-characteristics-for-detection-of-lung-cancer-in-pulmonary-nodules
#10
Jie Ma, Maria A Guarnera, Wenxian Zhou, HongBin Fang, Feng Jiang
Lung cancer early detection by low-dose computed tomography (LDCT) can reduce the mortality. However, LDCT increases the number of indeterminate pulmonary nodules (PNs), whereas 95% of the PNs are ultimately false positives. Modalities for specifically distinguishing between malignant and benign PNs are urgently needed. We previously identified a panel of peripheral blood mononucleated cell (PBMC)-miRNA (miRs-19b-3p and -29b-3p) biomarkers for lung cancer. This study aimed to evaluate efficacy of integrating biomarkers and clinical and radiological characteristics of smokers for differentiating malignant from benign PNs...
November 24, 2016: Translational Oncology
https://www.readbyqxmd.com/read/27875217/automatic-scoring-of-multiple-semantic-attributes-with-multi-task-feature-leverage-a-study-on-pulmonary-nodules-in-ct-images
#11
Sihong Chen, Jing Qin, Xing Ji, Baiying Lei, Tianfu Wang, Dong Ni, Jie-Zhi Cheng
The gap between the computational and semantic features is the one of major factors that bottlenecks the computer-aided diagnosis (CAD) performance from clinical usage. To bridge this gap, we exploit three multi-task learning (MTL) schemes to leverage heterogeneous computational features derived from deep learning models of stacked denoising autoencoder (SDAE) and convolutional neural network (CNN), as well as hand-crafted Haar-like and HoG features, for the description of 9 semantic features for lung nodules in CT images...
November 16, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/27871629/radiography-nomography-utility-of-a-calculator-in-rational-preoperative-decision-making-for-subsolid-pulmonary-nodules
#12
EDITORIAL
Bryan M Burt
No abstract text is available yet for this article.
November 3, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27871249/benign-clear-cell-sugar-tumor-of-the-lung-in-a-patient-with-birt-hogg-dub%C3%A3-syndrome-a-case-report
#13
Yoko Gunji-Niitsu, Toshio Kumasaka, Shigehiro Kitamura, Yoshito Hoshika, Takuo Hayashi, Hitoshi Tokuda, Riichiro Morita, Etsuko Kobayashi, Keiko Mitani, Mika Kikkawa, Kazuhisa Takahashi, Kuniaki Seyama
BACKGROUND: Birt-Hogg-Dubé (BHD) syndrome is a rare inherited autosomal genodermatosis and caused by germline mutation of the folliculin (FLCN) gene, a tumor suppressor gene of which protein product is involved in mechanistic target of rapamycin (mTOR) signaling pathway regulating cell growth and metabolism. Clinical manifestations in BHD syndrome is characterized by fibrofolliculomas of the skin, pulmonary cysts with or without spontaneous pneumothorax, and renal neoplasms. There has been no pulmonary neoplasm reported in BHD syndrome, although the condition is due to deleterious sequence variants in a tumor suppressor gene...
November 21, 2016: BMC Medical Genetics
https://www.readbyqxmd.com/read/27870729/aggressive-digital-papillary-adenocarcinoma-with-multiple-organ-metastases-a-case-report-and-review-of-the-literature
#14
Tadahiro Kobayashi, Azusa Hiura, Kyosuke Oishi, Shintaro Maeda, Andres James Le Pavoux, Kuniaki Ohara, Hironori Uruga
Aggressive digital papillary adenocarcinoma (ADPA) is a rare sweat gland neoplasm with a high recurrence rate and metastatic potential. In this study, the authors describe a case that originally appeared to benign spiradenoma, but took an ominous course eventually resulting in the diagnosis of ADPA. A 73-year-old woman developed a gradually growing nodule on the second toe of her left foot, which she had first noticed 4 years previously. An excisional biopsy was performed followed by histological examination...
December 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27870624/differentiating-between-subsolid-and-solid-pulmonary-nodules-at-ct-what-is-our-main-task
#15
Hongliang Sun, Wu Wang
No abstract text is available yet for this article.
December 2016: Radiology
https://www.readbyqxmd.com/read/27867557/clinical-analysis-of-non-aids-patients-pathologically-diagnosed-with-pulmonary-cryptococcosis
#16
Kaixiong Liu, Haibo Ding, Bing Xu, Ruixiong You, Zhen Xing, Jianfeng Chen, Qichang Lin, Jieming Qu
BACKGROUND: Pulmonary cryptococcosis (PC) was not a rare infectious disease in non-AIDS patients. However, data on the immune status were lacking in southern China for comparative analysis of differences between immunocompromised and immunocompetent hosts. This study was to investigate the epidemiological, clinical, radiological, and treatment profiles for patients with PC. METHODS: We performed a retrospective review of 88 patients diagnosed with tissue-confirmed PC who were not HIV-infected from 2003 to 2013...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27865474/tubeless-uniportal-thoracoscopic-wedge-resection-for-peripheral-lung-nodules
#17
Shun-Mao Yang, Man-Ling Wang, Ming-Hui Hung, Hsao-Hsun Hsu, Ya-Jung Cheng, Jin-Shing Chen
BACKGROUND: Endotracheal intubation and chest tube drainage are considered mandatory for thoracoscopic pulmonary resection. The management of peripheral lung nodules by tubeless uniportal thoracoscopic surgical repair has not been reported previously. METHODS: From October 2015 through January 2016, 30 consecutive patients with peripheral lung nodules underwent uniportal thoracoscopic wedge resection without endotracheal intubation and chest tube drainage (tubeless group)...
November 16, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27865146/a-case-report-of-successful-diagnosis-of-a-pulmonary-nodule-by-a-survey-of-oncogenic-mutations-primary-lung-carcinoma-or-pulmonary-metastasis
#18
Akira Haro, Erina Kuramitsu, Ichiro Yamamoto, Yasuro Fukuyama
INTRODUCTION: The number of patients diagnosed with solid carcinomas is increasing, and the most common site of metastasis is the lungs. It is often difficult to make a differential diagnosis between primary lung carcinoma and metastatic lung tumor in using histological examination and by determining their immunohistological status. PRESENTATION: A 64-years-old man presented with dyspnea with chest computed tomography (CT) findings of a pulmonary tumor, and afterwards suffered from a sudden bowel hemorrhaged due to colorectal carcinoma...
November 3, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27856118/computer-aided-detection-of-pulmonary-nodules-using-dynamic-self-adaptive-template-matching-and-a-flda-classifier
#19
Jing Gong, Ji-Yu Liu, Li-Jia Wang, Bin Zheng, Sheng-Dong Nie
Improving the performance of computer-aided detection (CAD) system for pulmonary nodules is still an important issue for its future clinical applications. This study aims to develop a new CAD scheme for pulmonary nodule detection based on dynamic self-adaptive template matching and Fisher linear discriminant analysis (FLDA) classifier. We first segment and repair lung volume by using OTSU algorithm and three-dimensional (3D) region growing. Next, the suspicious regions of interest (ROIs) are extracted and filtered by applying 3D dot filtering and thresholding method...
November 14, 2016: Physica Medica: PM
https://www.readbyqxmd.com/read/27843764/management-of-asymptomatic-pulmonary-vein-aneurysm
#20
Jason Coffman, Kristi Pence, Puja G Khaitan, Edward Y Chan, Min P Kim
Aneurysm of a pulmonary vein is a rare vascular anomaly that is usually discovered incidentally as a pulmonary nodule or mediastinal mass. Most patients do not have any symptoms but some patients can present with dyspnea, hemoptysis, or cerebral thromboembolism. Proper diagnosis is crucial as to avoid unnecessary testing or surgical procedures. We highlight a case of an asymptomatic 59-year-old female with a pulmonary vein aneurysm presenting as a 1.5 cm right infrahilar nodule on contrast-enhanced CT during evaluation for acute cholecystitis...
2017: Respiratory Medicine Case Reports
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