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https://www.readbyqxmd.com/read/28329598/successful-treatment-of-melkersson-rosenthal-syndrome-with-dapsone-a-case-report-and-review-of-the-literature
#1
Nazan Emiroglu, Ozlem Su, Fatma Pelin Cengiz, Nahide Onsun
Melkersson-Rosenthal syndrome (MRS) is a rare disease characterized by a triad of relapsing or persistent orofacial edema, recurrent lower motor neuron facial nerve palsy and fissured tongue. Acute, painless, non-erythematosus orofacial edema is observed in all patients. We report a case of a 13-year-old girl who presented with a 2-year history of swelling of the upper lip, facial paralysis, and fissured tongue; she was treated successfully with dapsone.
October 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28299356/an-exome-sequencing-study-of-moebius-syndrome-including-atypical-cases-reveals-an-individual-with-cfeom3a-and-a-tubb3-mutation
#2
Ronak M Patel, David Liu, Claudia Gonzaga-Jauregui, Shalini Jhangiani, James T Lu, V Reid Sutton, Susan D Fernbach, Mahshid Azamian, Lisa White, Jane C Edmond, Evelyn A Paysse, John W Belmont, Donna Muzny, James R Lupski, Richard A Gibbs, Richard Alan Lewis, Brendan H Lee, Seema R Lalani, Philippe M Campeau
Moebius syndrome is characterized by congenital unilateral or bilateral facial and abducens nerve palsies (sixth and seventh cranial nerves) causing facial weakness, feeding difficulties, and restricted ocular movements. Abnormalities of the chest wall such as Poland anomaly and variable limb defects are frequently associated with this syndrome. Most cases are isolated; however, rare families with autosomal dominant transmission with incomplete penetrance and variable expressivity have been described. The genetic basis of this condition remains unknown...
March 2017: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/28296237/inpatient-treatment-of-patients-with-acute-idiopathic-peripheral-facial-palsy-a-population-based-healthcare-research-study
#3
Katharina Plumbaum, Gerd Fabian Volk, Daniel Boeger, Jens Buentzel, Dirk Esser, Andreas Steinbrecher, Katrin Hoffmann, Peter Jecker, Andreas Mueller, Gerald Radtke, Otto W Witte, Orlando Guntinas-Lichius
OBJECTIVES: To determine the inpatient management for patients with acute idiopathic facial palsy (IFP) in Thuringia, Germany. DESIGN: Population-based study. SETTING: All inpatients with IFP in all hospitals with departments of otolaryngology and neurology in 2012 in the German federal state Thuringia. MAIN OUTCOME MEASURES: Patients' characteristics and treatment were compared between departments, and the probability of recovery was tested...
March 10, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28293537/a-rare-case-of-concomitant-sicca-keratopathy-and-ipsilateral-central-facial-palsy-in-wallenberg-s-dorsolateral-medullary-syndrome
#4
Deborah De Bruyn, Elisabeth Van Aken, Kristien Herman
Objective: To describe a patient with a right-sided supranuclear facial palsy and concomitant sicca keratopathy of the right eye following right-sided dorsolateral medullary infarction. Methods: Our patient underwent a complete ophthalmologic and neurologic examination including biomicroscopy, fundus examination, cranial nerve examination, Shirmer I test, and magnetic resonance imaging of the brain. Results: A 61-year-old woman presented in emergency with a central facial nerve palsy on the right side and truncal ataxia...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28291204/-staged-complex-treatment-of-paralytic-lagophthalmos-case-report
#5
M B Gushchina, S A Mal'kov, E V Kovshun, N S Yuzhakova
Paralytic lagophthalmos, resulting from facial nerve palsy, is a difficult medical and social issue that requires cooperation of different specialists. Complications that arise in paralytic lagophthalmos may cause significant vision loss and even eye loss. Various techniques of paralytic lagophthalmos correction are used to protect the cornea and restore eyelid anatomy and functions. These comprise palliative (conservative), surgical, and alternative treatments (such as botulinum toxin type A therapy). Surgical treatment of paralytic lagophthalmos patients often has to be staged and complex...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28283471/unilateral-facial-nerve-palsy-as-an-early-presenting-symptom-of-relapse-in-a-paediatric-patient-with-acute-lymphoblastic-leukaemia
#6
Leslie Y Chiang, John Ross Crawford, Dennis John Kuo
No abstract text is available yet for this article.
March 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28274058/evaluation-of-efficacy-of-intraligamentary-injection-technique-for-extraction-of-mandibular-teeth-a-prospective-study
#7
Raunak Pradhan, Deepak Kulkarni, Lakshmi Shetty
INTRODUCTION: Fear of dental pain is one of the most common reasons for delaying dental treatment. Local Anaesthesia (LA) is the most commonly employed technique of achieving pain control in dentistry. Pterygomandibular Nerve Block (PNB), for achieving mandibular anaesthesia has been the traditional technique used and is associated with a few set of complications which include pain, nerve injury, trismus, and rarely facial nerve palsy, and sustained soft tissue anaesthesia. These complications have resulted in a rapid need for research on alternative local anaesthetic techniques...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28268107/prosthetic-bypass-for-restenosis-after-endarterectomy-or-stenting-of-the-carotid-artery
#8
Giulio Illuminati, Romain Belmonte, Fabrice Schneider, Giulia Pizzardi, Francesco G Calió, Jean-Baptiste Ricco
OBJECTIVE: The objective of this study was to evaluate the results of prosthetic carotid bypass (PCB) with polytetrafluoroethylene (PTFE) grafts as an alternative to carotid endarterectomy (CEA) in treatment of restenosis after CEA or carotid artery stenting (CAS). METHODS: From January 2000 to December 2014, 66 patients (57 men and 9 women; mean age, 71 years) presenting with recurrent carotid artery stenosis ≥70% (North American Symptomatic Carotid Endarterectomy Trial [NASCET] criteria) were enrolled in a prospective study in three centers...
March 4, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28254601/electromyographically-guided-nerve-combing-makes-microvascular-decompression-more-successful-in-hemifacial-spasm-with-persistent-abnormal-muscle-response
#9
Xin Zhang, Jin Zhu, Yin-Da Tang, Hua Zhao, Ting-Ting Ying, Yan Yuan, Shi-Ting Li
BACKGROUND: Microvascular decompression (MVD) of the facial nerve monitored intra-operatively by abnormal muscle response (AMR) activity is a common treatment for hemifacial spasm. However, AMR frequently persists after MVD, for which electromyographically (EMG)-guided nerve combing is sometimes recommended. Because no research regarding the success of EMG-guided nerve combing has been published, we compared the effectiveness of nerve combing after MVD with simple MVD in cases including persistent AMR...
February 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28248607/multivariate-analysis-of-factors-influencing-facial-nerve-outcome-following-microsurgical-resection-of-vestibular-schwannoma
#10
Renato Torres, Yann Nguyen, Antoine Vanier, Mustapha Smail, Evelyne Ferrary, Olivier Sterkers, Michel Kalamarides, Daniele Bernardeschi
Objective To assess through multivariate analysis the clinical pre- and intraoperative factors of facial nerve outcomes at day 8 and 1-year recovery of facial palsy, as compared with day 8 status among patients who underwent total resection of unilateral vestibular schwannoma. Study Design Case series with chart review. Setting Tertiary referral center. Subjects and Methods This study included 229 patients with preoperative normal facial function and anatomic preservation of the facial nerve. Clinical, radiologic, and intraoperative factors were assessed according to facial nerve function at day 8 and 1 year...
March 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28246588/intermittent-facial-spasms-as-the-presenting-sign-of-a-recurrent-pleomorphic-adenoma
#11
Rosalie A Machado, Sami P Moubayed, Azita Khorsandi, Juan C Hernandez-Prera, Mark L Urken
The intimate anatomical relationship of the facial nerve to the parotid parenchyma has a significant influence on the presenting signs and symptoms, diagnosis and treatment of parotid neoplasms. However, to our knowledge, hyperactivity of this nerve, presenting as facial spasm, has never been described as the presenting sign or symptom of a parotid malignancy. We report a case of carcinoma arising in a recurrent pleomorphic adenoma of the left parotid gland (i.e., carcinoma ex pleomorphic adenoma) that presented with hemifacial spasms...
February 10, 2017: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28219164/-a-combination-use-of-endoscope-and-microscope-in-cerebral-pontine-angle-surgery
#12
Z Y Wang, H Jia, J Yang, H Y Tan, H Wu
Objective: To evaluate the application of combination use of microscope and endoscope in cerebral pontine angle (CPA) surgery. Methods: A total of 72 patients undergone lateral skull base surgeries via endoscope under microscopic control from January 2006 to January 2015 was reviewed respectively. The patients including 35 males and 37 females were composed of 22 cases of vestibular swannnomas, 45 cases of cranial neuropathy and 5 cases of CPA chelesteatoma. Twenty cases of vestibular swannnomas, 15 cases of cranial neuropathy and 2 cases of CPA chelesteatoma undergone the surgery via retrosigmoid approach, while other cases undergone the surgery via retrolabyrinthine approach...
February 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28218014/bilateral-otoneurological-pathology-to-operate-or-not
#13
Shivun Khosla, Matthew Elliot, Neil Donnelly
OBJECTIVE: To illustrate our experience when managing a complex patient with potentially life-threatening bilateral otological disease facing multisensory compromise including complete loss of audiovestibular function and visual disturbance Clinical presentation: A 67 year old lady, presented with a large left vestibular schwannoma and extensive right cholesteatoma encircling the otic capsule. She underwent translabyrinthine resection of the vestibular schwannoma, resulting in profound sensorineural hearing loss, vestibular hypofunction and corneal scarring following an initial temporary facial palsy...
March 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/28217155/acute-bulbar-palsy-plus-syndrome-a-rare-variant-of-guillain-barre-syndrome
#14
Sanghamitra Ray, Prakash Chand Jain
Guillain-Barre syndrome (GBS) is the most common cause of acute flaccid paralysis worldwide both in adult and pediatric population. Although flaccid paralysis is the hallmark of this disease, there are some rare variants which may be easily missed unless suspected. Here, we present a very rare variant of GBS - acute bulbar palsy plus syndrome in a pediatric patient. A 13-year-old female child presented with right-sided lower motor neuron type of facial palsy and palsy of bilateral glossopharyngeal and vagus nerve of 2 weeks duration...
October 2016: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28211985/a-girl-with-developmental-delay-ataxia-cranial-nerve-palsies-severe-respiratory-problems-in-infancy-expanding-ndst1-syndrome
#15
Linlea Armstrong, Maja Tarailo-Graovac, Graham Sinclair, Kimberly I Seath, Wyeth W Wasserman, Colin J Ross, Clara D M van Karnebeek
NDST1 encodes an enzyme involved in the first steps in the synthesis of heparan sulfate chains, proteoglycans that are regulators found on the cell surface and in the extracellular matrix. Eight individuals homozygous for one of four family-specific missense mutations in the sulfotransferase domain of the enzyme have been described. They have intellectual disability. Some additionally had hypotonia, ataxia. seizures, and/or short stature, but none had history of respiratory problems. No humans with homozygous null mutations are known...
March 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28197706/efficacy-of-the-red-blood-cell-distribution-width-for-predicting-the-prognosis-of-bell-palsy-a-pilot-study
#16
Yuichiro Horibe, Tohru Tanigawa, Rei Shibata, Hiroshi Nonoyama, Fumiya Kano, Satoshi Yamaguchi, Kenta Murotani, Takaki Ogawa, Hiromi Ueda
The aim of this study was to investigate the association between RDW values and the prognosis of patients with Bell palsy in an effort to find a prognostic biomarker that predicts recovery from Bell palsy. We measured RDW and evaluated facial movement in 61 patients with Bell palsy aged 50 years and less. All patients were treated with a steroid plus an antiviral agent. Seven patients underwent surgery for facial nerve decompression. During the post-treatment period, patients with a Yanagihara grading score of 36 or more were regarded as having a satisfactory recovery...
February 14, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28193257/bell-s-palsy-in-children-bellpic-protocol-for-a-multicentre-placebo-controlled-randomized-trial
#17
Franz E Babl, Mark T Mackay, Meredith L Borland, David W Herd, Amit Kochar, Jason Hort, Arjun Rao, John A Cheek, Jeremy Furyk, Lisa Barrow, Shane George, Michael Zhang, Kaya Gardiner, Katherine J Lee, Andrew Davidson, Robert Berkowitz, Frank Sullivan, Emily Porrello, Kim Marie Dalziel, Vicki Anderson, Ed Oakley, Sandy Hopper, Fiona Williams, Catherine Wilson, Amanda Williams, Stuart R Dalziel
BACKGROUND: Bell's palsy or acute idiopathic lower motor neurone facial paralysis is characterized by sudden onset paralysis or weakness of the muscles to one side of the face controlled by the facial nerve. While there is high level evidence in adults demonstrating an improvement in the rate of complete recovery of facial nerve function when treated with steroids compared with placebo, similar high level studies on the use of steroids in Bell's palsy in children are not available. The aim of this study is to assess the utility of steroids in Bell's palsy in children in a randomised placebo-controlled trial...
February 13, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28192771/miescher-s-cheilitis-surgical-management-and-long-term-outcome-of-an-extremely-severe-case
#18
Alessandro Innocenti, Marco Innocenti, Cecilia Taverna, Dario Melita, Francesco Mori, Francesco Ciancio, Vincenzo De Giorgi, Paola Parronchi, Alessandra Vultaggio, Andrea Matucci
INTRODUCTION: Miescher's cheilitis is clinically characterized by persistent swelling of the lip(s). Its pathogenesis is still unknown. Histopathologically is characterized by sub-epithelial edema, increased number of dilated lymphatic vessels and an inflammatory infiltrate and/or non-caseating/non- necrotic granulomas. Even if the disorder must be controlled by medical therapy, surgery may be required to treat most severe cases. PRESENTATION OF THE CASE: We report a 30-year-old man who presented a persistent swelling of both lips since 8 years, previously treated with intralesional steroid and immunosuppressive therapy...
January 30, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28178096/relative-location-of-fundus-meatus-acustici-interni-via-porus-acusticus-internus-in-facial-nerve-decompression
#19
Xu Liu, Haodong Wang, Kailiang Cheng, Youqiong Li
Facial neural edema is the pathophysiological base of Bell's palsy. The middle cranial fossa approach is used to relieve the oppression of facial nerve at its most narrow course in the facial canal. In this research, the authors mainly discussed the internal auditory canal segment of facial nerve, completely in the shadow of the bony structure, which is inconvenient for transmastoid decompression. Therefore, the objective was to explore the definite position of the fundus meatus acustici interni from internal acoustic pore...
February 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28168888/cutaneous-sensibility-changes-in-bell-s-palsy-patients
#20
Carlos Andrés Cárdenas Palacio, Francisco Alejandro Múnera Galarza
Objective Bell's palsy is a cranial nerve VII dysfunction that renders the patient unable to control facial muscles from the affected side. Nevertheless, some patients have reported cutaneous changes in the paretic area. Therefore, cutaneous sensibility changes might be possible additional symptoms within the clinical presentation of this disorder. Accordingly, the aim of this research was to investigate the relationship between cutaneous sensibility and facial paralysis severity in these patients. Study Design Prospective longitudinal cohort study...
February 1, 2017: Otolaryngology—Head and Neck Surgery
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